Segmented evaluation method for morphological change development of abdominal aortic aneurysm

Abstract

The invention discloses a segmented evaluation method for morphological change development of abdominal aortic aneurysm, which comprises the following steps of: 1, performing three-dimensional modeling on the abdominal aortic aneurysm based on a clinical image; 2, determining the positions of the proximal end tumor neck and the telecentric end tumor neck of the aneurysm through a clinical image or a three-dimensional model, obtaining the midpoints of the proximal end tumor neck and the telecentric end tumor neck of the aneurysm, and extracting the vertical distance between the two midpoints as the vertical length (L) of the aneurysm; 3, on the basis of the obtained vertical length L of the aneurysm, obtaining n-1 sections (Slice) which equally divide the abdominal aortic aneurysm into n sections, and the length of each section is L / n; 4, obtaining various morphological parameters at different sections; and 5, quantitatively monitoring and evaluating the morphological change development of each section of the abdominal aortic aneurysm in combination with the result of the step 4.

Description

Technical Field

[0001] The invention belongs to the field of abdominal aortic aneurysm assessment, and in particular relates to a segmented assessment method for the morphological change and development of abdominal aortic aneurysm. Background Art

[0002] Clinically, since the rupture of abdominal aortic aneurysm (AAA) is accompanied by a very high mortality rate, the prediction of the rupture risk of patients with abdominal aortic aneurysm is often extremely important. Among them, monitoring the development of AAA and assessing the risk of aneurysm rupture based on morphological parameters have been widely used in clinical practice. The maximum size of the aneurysm is currently the most common morphological indicator for assessing the risk of AAA rupture. By measuring the maximum diameter (MaximumDiameter) of the entire aneurysm and comparing it with the critical value in the current medical guidelines, the clinical conservative treatment or surgical intervention can be guided. According to a large sample clinical survey in the relevant field, when the maximum diameter of female AAA is greater than 5cm or the size of male AAA is greater than 5.5cm, it is usually considered that such patients have a greater risk of aneurysm rupture and should undergo surgical intervention. However, it must be mentioned that the method of morphological monitoring of AAA rupture is not limited to this. Other morphological parameters, including aneurysm neck size, aneurysm eccentricity, aneurysm growth rate, etc., have also been proposed as indicators for monitoring the risk of aneurysm rupture, but the application of these parameters is not as extensive as the maximum size of the aneurysm.

[0003] On the other hand, while the maximum size of AAA is widely used in clinical practice, a large number of clinical investigations and studies have observed that aneurysm rupture does not only occur when the size is large, but also in some patients whose maximum AAA size has not yet reached the surgical intervention indicator. This makes the accuracy of assessing aneurysm rupture by the maximum size of the aneurysm questionable, and some studies even believe that the risk of aneurysm rupture assessed by the maximum size of the aneurysm is not reliable. In fact, the maximum size of AAA can only focus on a specific position in the overall morphology of AAA, but cannot effectively monitor the morphological changes of other parts of the aneurysm. The morphological development of the rest of the AAA cannot be fully reflected by this method of monitoring the morphology of the aneurysm. This single parameter cannot fully describe other relevant morphological information of the aneurysm. Aneurysm rupture often occurs only at a local point, but the rupture location does not necessarily occur at the maximum size of AAA. Therefore, clinical monitoring of the maximum size of AAA alone will make it difficult to capture local morphological changes in other parts of the aneurysm, and thus cannot effectively predict the risk of aneurysm rupture. Summary of the invention

[0004] In order to solve the above problems existing in the prior art, the present invention slices the AAA and then monitors the morphological parameters of each slice, quantitatively evaluates the changes in the morphological parameters of the slices at different positions of the AAA, so as to effectively grasp the morphological development of each slice position of the aneurysm, and provide a useful supplement for clinical monitoring of AAA growth changes and rupture risks. The technical solution adopted by the present invention is:

[0005] A segmented evaluation method for the morphological changes and development of abdominal aortic aneurysm comprises the following steps:

[0006] Step 1: 3D modeling of abdominal aortic aneurysm based on clinical images;

[0007] Step 2: Obtain the location of the proximal neck and the distal neck of the aneurysm through clinical images or three-dimensional models, determine the midpoint of the proximal neck and the distal neck of the aneurysm, and extract the vertical distance between the two midpoints.

[0008] as the vertical length of the aneurysm (L);

[0009] Step 3: Based on the obtained vertical length L of the aneurysm, obtain n-1 slices that divide the abdominal aortic aneurysm into n segments, and the length of each segment is L / n;

[0010] Step 4: Obtain various morphological parameters at different sections;

[0011] Step 5: Combined with the results of step 4, quantitative monitoring and evaluation of the morphological changes and development of each segment of the abdominal aortic aneurysm are performed.

[0012] Further, the step 4 comprises the following steps:

[0013] Step 41: Since the shape of the aneurysm section is not a regular circle, we define the calculation formula of the equivalent diameter based on the cross-sectional area of ​​the section as follows:

[0014]

[0015] Where i represents the i-th slice among n-1 slices, CSA i (Cross Section Area) represents the cross-sectional area at section i, and its dimension is cm 2 , E.D. i (Equivalent Diameter) is the equivalent diameter at the i-th section, and its dimension is cm;

[0016] Step 42: Calculate the cross-sectional area change value VCSA at the i-th section of the abdominal aortic aneurysm a-b,i(Variation of CSA), the ratio of the cross-sectional area of ​​the i-th section of the abdominal aorta RCSA a-b,i (Ratio of CSA), annual change in cross-sectional area of ​​abdominal aortic aneurysm at the i-th section between two follow-up visits VCSAY a-b,i (Variation of CSA per Year):

[0017] VCSA a-b,i =CSA b,i -CSA a,i

[0018]

[0019] Among them, a and b represent two different follow-up visits, VCSA a-b,i (Variation of CSA) means the change in cross-sectional area of ​​the abdominal aortic aneurysm at the i-th section during the two follow-up periods a and b, and its dimension is cm 2 . When the value is greater than 0, it indicates that the cross-sectional area of ​​the AAA section is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when the value is less than 0, it indicates that the cross-sectional area of ​​the AAA section is decreasing, the aneurysm is shrinking, the risk of aneurysm rupture is correspondingly decreasing, and the patient's condition is improving; the larger the absolute value of the value, the more unstable the patient's aneurysm is, and the more obvious the morphological changes are; the smaller the absolute value of the value, the more stable the patient's aneurysm is, and the less obvious the morphological changes are.

[0020] In addition, RCSA a-b,i (Ratio of CSA) represents the ratio of the cross-sectional area of ​​the i-th section of the abdominal aorta between the two follow-up visits a and b, which is a dimensionless parameter greater than 0. When the value is greater than 1, it indicates that the cross-sectional area of ​​the AAA section is increasing, the aneurysm wall is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when the value is less than 1, it indicates that the surface area of ​​the AAA section is decreasing, the aneurysm wall is shrinking, the risk of aneurysm rupture is correspondingly decreasing, and the patient's condition is improving; the greater the deviation of the value from 1, the more unstable the patient's aneurysm is, and the more obvious the morphological changes are; when the value is closer to 1, the more stable the patient's aneurysm is, and the less obvious the morphological changes are.

[0021] Finally, VCSAY a-b,i (Variation of Cross Section Area per Year) means the annual change in the cross-sectional area of ​​the i-th section of the abdominal aortic aneurysm during the two follow-up periods a and b, and its dimension is cm2 / year. When the value is greater than 0, it indicates that the cross-sectional area of ​​AAA at this section is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when the value is less than 0, it indicates that the cross-sectional area of ​​AAA at this section is decreasing, the aneurysm wall is shrinking, the risk of aneurysm rupture is correspondingly decreasing, and the patient's condition is improving; the larger the absolute value of the value, the more unstable the patient's aneurysm is, and the more obvious the morphological changes are; the smaller the absolute value of the value, the more stable the patient's aneurysm is, and the less obvious the morphological changes are.

[0022] Step 43: Calculate the change in equivalent diameter VED of the abdominal aortic aneurysm at the i-th section a-b,i (Variation of ED), the ratio of equivalent diameters of the abdominal aorta at the i-th section RED a-b,i (Ratio of ED), annual change in equivalent diameter of abdominal aortic aneurysm at the i-th section between two follow-up visits VEDY a-b,i (Variation of ED per Year):

[0023] VED a-b,i =ED b,i -ED a,i

[0024]

[0025] Among them, VED a-b,i (Variation of ED) represents the change in the equivalent diameter of the i-th section of the abdominal aortic aneurysm during the two follow-up visits a and b, and its dimension is cm. When this value is greater than 0, it indicates that the equivalent diameter of the AAA at this section is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when this value is less than 0, it indicates that the equivalent diameter of the AAA at this section is decreasing, the aneurysm is shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving; when the absolute value of this value is larger, it indicates that the patient's aneurysm is more unstable and the morphological changes are more obvious; when the absolute value of this value is smaller, it indicates that the patient's aneurysm is more stable and the morphological changes are less obvious.

[0026] In addition, RED a-b,i(Ratio of ED) represents the ratio of the equivalent diameters at the i-th section of the abdominal aorta during the two follow-up periods a and b, which is a dimensionless parameter greater than 0. When the value is greater than 1, it indicates that the equivalent diameter at the section of the AAA is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when the value is less than 1, it indicates that the equivalent diameter at the section of the AAA is decreasing, the aneurysm wall is shrinking, the risk of aneurysm rupture is correspondingly decreasing, and the patient's condition is improving; the greater the deviation of the value from 1, the more unstable the patient's aneurysm is, and the more obvious the morphological changes are; when the value is closer to 1, the more stable the patient's aneurysm is, and the less obvious the morphological changes are.

[0027] Finally, VEDY a-b,i (Variation of Equivalent Diameter per Year) means the annual change of equivalent diameter of abdominal aortic aneurysm at the i-th section during the two follow-up periods a and b, and its dimension is cm / year. When this value is greater than 0, it indicates that the equivalent diameter of AAA at this section is increasing, the aneurysm wall is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when this value is less than 0, it indicates that the equivalent diameter of AAA at this section is decreasing, the aneurysm wall is shrinking, the risk of aneurysm rupture is correspondingly decreasing, and the patient's condition is improving; the larger the absolute value of this value, the more unstable the patient's aneurysm is, and the more obvious the morphological changes are; when the absolute value of this value is smaller, it indicates that the patient's aneurysm is more stable, and the morphological changes are less obvious.

[0028] The beneficial effects of the present invention are:

[0029] First, the method introduced in this article is a new method for monitoring changes in aneurysm status that has not been mentioned in previous studies. Secondly, the acquisition of this method is mainly based on the patient's clinical medical images, and no other additional examinations are required. It is a non-invasive analysis technology. Finally, this parameter is very intuitive in clinical use, and its changes can also be directly used to describe the changes in aneurysm status during different follow-up processes, which can effectively provide quantitative morphological references for doctors' clinical decision-making. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 Clinical images and three-dimensional model reconstruction during the follow-up of abdominal aortic aneurysm in the present invention, where (a) is four months before aneurysm rupture, (b) is one day before aneurysm rupture, and (c) is the day of aneurysm rupture.

[0031] Figure 2 It is a schematic diagram of the regional morphological parameters and segmentation method of abdominal aortic aneurysm in the present invention.

[0032] Figure 3 The morphological parameters related to the abdominal aortic aneurysm area during the two follow-up periods were statistically analyzed. DETAILED DESCRIPTION

[0033] The present invention will be further described below with reference to the accompanying drawings and the accompanying drawings.

[0034] In order to more clearly understand the above-mentioned purpose, features and advantages of the present invention, the present invention is described in detail below in conjunction with the accompanying drawings and specific embodiments. It should be noted that the embodiments of the present application and the features in the embodiments can be combined with each other without conflict.

[0035] The terms “first”, “second”, “third”, etc. are only used for distinguishing descriptions and should not be understood as indicating or implying relative importance.

[0036] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0037] The specific implementation of the present invention is described in detail below in conjunction with the accompanying drawings. It should be understood that the specific implementation described here is only used to illustrate and explain the present invention, and is not used to limit the present invention.

[0038] Embodiment 1:

[0039] like Figure 2 As shown, a segmented evaluation method for the morphological changes and development of abdominal aortic aneurysm comprises the following steps:

[0040] Step 1: 3D modeling of abdominal aortic aneurysm based on clinical images;

[0041] Step 2: Obtain the location of the proximal neck and the distal neck of the aneurysm through clinical images or three-dimensional models, determine the midpoint of the proximal neck and the distal neck of the aneurysm, and extract the vertical distance between the two midpoints.

[0042] as the vertical length of the aneurysm (L);

[0043] Step 3: Based on the obtained vertical length L of the aneurysm, obtain n-1 slices that divide the abdominal aortic aneurysm into n segments, and the length of each segment is L / n;

[0044] Step 4: Obtain various morphological parameters at different sections;

[0045] Step 5: Combined with the results of step 4, quantitative monitoring and evaluation of the morphological changes and development of each segment of the abdominal aortic aneurysm are performed.

[0046] First, we will reconstruct an accurate 3D model of the aneurysm area based on clinical medical images such as CTA and MRI during the patient's follow-up period. Figure 1 As shown in the figure, we take a patient who experienced a ruptured abdominal aortic aneurysm as an example. The patient's angiography (CTA) was collected four months before the rupture, one day before the rupture, and on the day of the rupture.

[0047] Then, we determine the location of the neck-proximal and neck-distal of the aneurysm based on clinical images or reconstructed 3D models, while ensuring that the patient's morphological information is not lost. We then extract the vertical distance between the midpoints of the two necks as the vertical length of the aneurysm (L). On this basis, the abdominal aortic aneurysm is divided into n segments by n-1 slices, each of which is L / n in length. The specific slice method is as follows: Figure 2 As shown in Figure 2. The size of n can be determined based on the length of the aneurysm itself, the thickness of the image layer, and the computer processing power. Furthermore, we counted the morphological parameters of each section of the aneurysm at different follow-up periods, and obtained various morphological parameters at different sections through calculation, including the cross-sectional area (CSA) and equivalent diameter at each section.

[0048] Equivalent Diameter (ED) is used to quantitatively monitor and evaluate the morphological changes and development of AAA at various sections.

[0049] Embodiment 2:

[0050] On the basis of Example 1, Figure 1 and 3 The step 4 comprises the following steps:

[0051] Step 41: Since the shape of the aneurysm section is an irregular circle, we define the calculation formula of the equivalent diameter based on the cross-sectional area of ​​the section as follows:

[0052]

[0053] Where i represents the i-th slice among n-1 slices, CSA i (Cross Section Area) represents the cross-sectional area at section i, and its dimension is cm 2 , E.D. i(Equivalent Diameter) is the equivalent diameter at the i-th section, and its dimension is cm;

[0054] Step 42: Calculate the cross-sectional area change value VCSA at the i-th section of the abdominal aortic aneurysm a-b,i (Variation of CSA), the ratio of the cross-sectional area of ​​the i-th section of the abdominal aorta RCSA a-b,i (Ratio of CSA), annual change in cross-sectional area of ​​abdominal aortic aneurysm at the i-th section between two follow-up visits VCSAY a-b,i (Variation of CSA per Year):

[0055] VCSA a-b,i =CSA b,i -CSA a,i

[0056]

[0057] Among them, a and b represent two different follow-up visits, VCSA a-b,i (Variation of CSA) means the change in cross-sectional area of ​​the abdominal aortic aneurysm at the i-th section during the two follow-up periods a and b, and its dimension is cm 2 .

[0058] In addition, RCSA a-b,i (Ratio of CSA) represents the ratio of the cross-sectional area of ​​the i-th section of the abdominal aorta between the two follow-up periods a and b, and is a dimensionless parameter greater than 0.

[0059] Finally, VCSAY a-b,i (Variation of Cross Section Area per Year) means the annual change in the cross-sectional area of ​​the i-th section of the abdominal aortic aneurysm during the two follow-up periods a and b, and its dimension is cm 2 / year.

[0060] Step 43: Calculate the change in equivalent diameter VED of the abdominal aortic aneurysm at the i-th section a-b,i (Variation of ED), the ratio of equivalent diameters of the abdominal aorta at the i-th section RED a-b,i (Ratio of ED), annual change in equivalent diameter of abdominal aortic aneurysm at the i-th section between two follow-up visits VEDY a-b,i (Variation of ED per Year):

[0061] VEDa-b,i =ED b,i -ED a,i

[0062]

[0063] Among them, VED a-b,i (Variation of ED) refers to the change in the equivalent diameter of the abdominal aortic aneurysm at the i-th section during the two follow-up periods a and b, and its dimension is cm.

[0064] In addition, RED a-b,i (Ratio of ED) represents the ratio of the equivalent diameters of the abdominal aorta at the i-th section during the two follow-up periods a and b, which is a dimensionless parameter greater than 0.

[0065] Finally, VEDY a-b,i Variation of Equivalent Diameter per Year means the annual variation of the equivalent diameter of the i-th section of the abdominal aortic aneurysm between the two follow-up periods a and b, and its dimension is cm / year.

[0066] Embodiment 3:

[0067] Based on Example 2, in step 5, when VCSA a-b,i When it is greater than 0, it indicates that the cross-sectional area of ​​the AAA segment is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when VCSA a-b,i When VCSA is less than 0, it indicates that the cross-sectional area of ​​the AAA is decreasing, the aneurysm is shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving. a-b,i The larger the absolute value, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,i The smaller the absolute value, the more stable the patient's aneurysm is and the less obvious the morphological changes are.

[0068] When RCSA a-b,i When it is greater than 1, it indicates that the cross-sectional area of ​​AAA is increasing, the aneurysm wall is growing, the risk of aneurysm rupture is increasing, and the patient's condition is deteriorating. a-b,i When it is less than 1, it indicates that the surface area of ​​the AAA segment is decreasing, the aneurysm wall is shrinking and shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving; when RCSA a-b,i The greater the deviation from 1, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,iThe closer it is to 1, the more stable the patient's aneurysm is and the less obvious the morphological changes are.

[0069] When VCSAY a-b,i When VCSAY is greater than 0, it indicates that the cross-sectional area of ​​AAA is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating. a-b,i When it is less than 0, it indicates that the cross-sectional area of ​​AAA at this section is decreasing, the aneurysm wall is shrinking and shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving; when VCSAY a-b,i The larger the absolute value, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,i The smaller the absolute value, the more stable the patient's aneurysm is and the less obvious the morphological changes are.

[0070] When VED a-b,i When it is greater than 0, it indicates that the equivalent diameter of AAA at this section is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when VED a-b,i When it is less than 0, it indicates that the equivalent diameter of AAA at this section is decreasing, the aneurysm is shrinking and shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving; when VED a-b,i The larger the absolute value, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,i The smaller the absolute value, the more stable the patient's aneurysm is and the less obvious the morphological changes are.

[0071] When RED a-b,i When it is greater than 1, it indicates that the equivalent diameter of AAA at this section is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when RED a-b,i When it is less than 1, it indicates that the equivalent diameter of AAA at this section is decreasing, the aneurysm wall is shrinking and shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving; when RED a-b,i The greater the deviation from 1, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,i The closer it is to 1, the more stable the aneurysm is and the less obvious the morphological changes are.

[0072] When VEDY a-b,i When VEDY is greater than 0, it indicates that the equivalent diameter of the AAA at that section is increasing, the aneurysm wall is growing and enlarging, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating. a-b,iWhen VEDY is less than 0, it indicates that the equivalent diameter of AAA at this section is decreasing, the aneurysm wall is shrinking and shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving. a-b,i The larger the absolute value, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,i The smaller the absolute value, the more stable the patient's aneurysm is and the less obvious the morphological changes are.

[0073] The present invention is not limited to the above-mentioned optional implementation modes. Anyone can derive other various forms of products under the inspiration of the present invention. However, no matter what changes are made in the shape or structure, all technical solutions that fall within the scope defined by the claims of the present invention fall within the protection scope of the present invention.

Claims

1. A segmented evaluation method for the morphological changes and development of abdominal aortic aneurysms, characterized by: The following steps are involved: Step 1: 3D modeling of abdominal aortic aneurysm based on clinical images; Step 2: Obtain the location of the proximal neck and the distal neck of the aneurysm through clinical images or three-dimensional models, determine the midpoint of the proximal neck and the distal neck of the aneurysm, and extract the vertical distance between the two midpoints as the vertical length of the aneurysm (L); Step 3: Based on the obtained vertical length L of the aneurysm, obtain n-1 slices that divide the abdominal aortic aneurysm into n segments, and the length of each segment is L / n; Step 4: Obtain various morphological parameters at different sections; Step 5: Combined with the results of step 4, quantitative monitoring and evaluation of the morphological changes and development of each segment of the abdominal aortic aneurysm are performed.

2. The segmented assessment method for the morphological changes and development of abdominal aortic aneurysm according to claim 1, characterized in that: The step 4 comprises the following steps: Step 41: Since the shape of the aneurysm section is an irregular circle, the calculation formula for defining the equivalent diameter is as follows: Where i represents the i-th slice among n-1 slices, CSA i (Cross Section Area) represents the cross-sectional area at section i, and its dimension is cm 2 , E.D. i (Equivalent Diameter) is the equivalent diameter at the i-th section, and its dimension is cm; Step 42: Calculate the cross-sectional area change value VCSA at the i-th section of the abdominal aortic aneurysm a-b,i (Variation of CSA), the ratio of the cross-sectional area of ​​the i-th section of the abdominal aorta RCSA a-b,i (Ratio of CSA), annual change in cross-sectional area of ​​abdominal aortic aneurysm at the i-th section between two follow-up visits VCSAY a-b,i (Variation of CSA per Year): VCSA a-b,i =CSA b,i -CSA a,i Among them, a and b represent two different follow-up visits, VCSA a-b,i It represents the change in cross-sectional area of ​​the abdominal aortic aneurysm at the i-th section during the two follow-up periods a and b, and its dimension is cm 2 ; RCSA a-b,i That is, it represents the ratio of the cross-sectional area of ​​the i-th section of the abdominal aorta during the two follow-up periods a and b, which is a dimensionless parameter greater than 0; VCSAY a-b,i That is, it represents the annual change in the cross-sectional area of ​​the abdominal aortic aneurysm at the i-th section during the two follow-up periods a and b, and its dimension is cm 2 / year; Step 43: Calculate the change in equivalent diameter VED of the abdominal aortic aneurysm at the i-th section a-b,i (Variation of ED), the ratio of equivalent diameters of the abdominal aorta at the i-th section RED a-b,i (Ratio of ED), annual change in equivalent diameter of abdominal aortic aneurysm at the i-th section between two follow-up visits VEDY a-b,i (Variation of ED per Year): BY a-b,i =ED b,i -OATH a,i Among them, VED a-b,i That is, it represents the change in the equivalent diameter of the abdominal aortic aneurysm at the i-th section during the two follow-up periods a and b, and its dimension is cm; RED a-b,i It represents the ratio of the equivalent diameter of the abdominal aorta at the i-th section during the two follow-up periods a and b, which is a dimensionless parameter greater than 0; VEDY a-b,i That is, it represents the annual change in the equivalent diameter of the abdominal aortic aneurysm at the i-th section during the two follow-up periods a and b, and its dimension is cm / year.

3. The segmented assessment method for the morphological changes and development of abdominal aortic aneurysm according to claim 2, characterized in that: In step 5, when VCSA a-b,i When it is greater than 0, it indicates that the cross-sectional area of ​​the AAA segment is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when VCSA a-b,i When VCSA is less than 0, it indicates that the cross-sectional area of ​​the AAA is decreasing, the aneurysm is shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving. a-b,i The larger the absolute value, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,i The smaller the absolute value, the more stable the patient's aneurysm is and the less obvious the morphological changes are. When RCSA a-b,i When it is greater than 1, it indicates that the cross-sectional area of ​​AAA is increasing, the aneurysm wall is growing, the risk of aneurysm rupture is increasing, and the patient's condition is deteriorating. a-b,i When it is less than 1, it indicates that the surface area of ​​the AAA segment is decreasing, the aneurysm wall is shrinking and shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving; when RCSA a-b,i The greater the deviation from 1, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,i The closer it is to 1, the more stable the aneurysm is and the less obvious the morphological changes are. When VCSAY a-b,i When VCSAY is greater than 0, it indicates that the cross-sectional area of ​​AAA is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating. a-b,i When it is less than 0, it indicates that the cross-sectional area of ​​AAA at that section is decreasing, the aneurysm wall is shrinking and shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving; When VCSAY a-b,i The larger the absolute value, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,i The smaller the absolute value, the more stable the patient's aneurysm is and the less obvious the morphological changes are. When VED a-b,i When it is greater than 0, it indicates that the equivalent diameter of AAA at this section is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when VED a-b,i When it is less than 0, it indicates that the equivalent diameter of AAA at this section is decreasing, the aneurysm is shrinking and shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving; when VED a-b,i The larger the absolute value, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,i The smaller the absolute value, the more stable the patient's aneurysm is and the less obvious the morphological changes are. When RED a-b,i When it is greater than 1, it indicates that the equivalent diameter of AAA at this section is increasing, the aneurysm is growing, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating; when RED a-b,i When it is less than 1, it indicates that the equivalent diameter of AAA at this section is decreasing, the aneurysm wall is shrinking and shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving; when RED a-b,i The greater the deviation from 1, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,i The closer it is to 1, the more stable the aneurysm is and the less obvious the morphological changes are. When VEDY a-b,i When VEDY is greater than 0, it indicates that the equivalent diameter of the AAA at that section is increasing, the aneurysm wall is growing and enlarging, the risk of aneurysm rupture is correspondingly increasing, and the patient's condition is deteriorating. a-b,i When VEDY is less than 0, it indicates that the equivalent diameter of AAA at this section is decreasing, the aneurysm wall is shrinking and shrinking, the risk of aneurysm rupture is correspondingly reduced, and the patient's condition is improving. a-b,i The larger the absolute value, the more unstable the aneurysm is and the more obvious the morphological changes are. a-b,i The smaller the absolute value, the more stable the patient's aneurysm is and the less obvious the morphological changes are.

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