Thrombus aspiration system and control method of thrombus aspiration system

Abstract

The present application relates to a thrombus aspiration system and a control method of the thrombus aspiration system, and relates to the technical field of medical equipment, which can improve the efficiency of thrombus aspiration. The intelligent control module in the system is configured to execute: according to the pressure data collected by the first pressure sensor and the pressure data collected by the second pressure sensor, determine the pressure difference between the proximal end and the distal end, and determine the pressure difference change rate of the pressure difference; according to the flow data collected by the flow sensor, determine the flow change rate of the blood flow in the aspiration catheter; according to the pressure difference change rate and the flow change rate, determine the medium type corresponding to the current aspiration medium of the aspiration catheter; when the aspiration medium is blood, the valve in the air pressure state conversion module is in a closed state and the blood is intermittently aspirated according to a preset frequency; when the aspiration medium includes a target volume of thrombus, determine the target frequency corresponding to the target volume, and while maintaining the aspiration, open and close the valve in the air pressure state conversion module multiple times according to the target frequency.

Description

Technical Field

[0001] The present application relates to the technical field of medical equipment, and in particular to a thrombus aspiration system and a control method for the thrombus aspiration system. Background Art

[0002] With the development of medical technology, thrombosis treatment has received more and more attention. In traditional thrombosis treatment, drug thrombolysis or surgical thrombectomy can be performed, but both methods have certain limitations. In order to optimize thrombosis treatment, thrombus aspiration came into being.

[0003] In the related technology, suction equipment is mainly used to directly suction inside the target object's body. The suction process mainly relies on the negative pressure ability of the vacuum pump to achieve suction. The negative pressure of a common vacuum pump is about 98Kpa, which is close to vacuum and cannot significantly improve performance. When a harder thrombus exists in the target object's body, the suction equipment cannot efficiently complete the thrombus suction. Summary of the invention

[0004] Based on this, it is necessary to provide a thrombus aspiration system and a control method for the thrombus aspiration system to address the above technical issues.

[0005] In a first aspect, the present application provides a thrombus aspiration system, the system comprising an air pressure state conversion module, an intelligent control module and an aspiration catheter, wherein a first pressure sensor and a second pressure sensor are respectively provided at a proximal end of the aspiration catheter close to the aspiration inlet and a distal end away from the aspiration inlet;

[0006] The intelligent control module is configured to perform:

[0007] During the suction process, the pressure difference between the proximal end and the distal end is determined based on the pressure data collected by the first pressure sensor and the pressure data collected by the second pressure sensor, and the pressure difference change rate of the pressure difference is determined; and the flow change rate of the blood flow in the suction catheter is determined based on the flow data collected by the flow sensor for monitoring the flow of the suction catheter;

[0008] Determining a medium type corresponding to a current suction medium of the suction conduit according to the pressure difference change rate and the flow rate change rate;

[0009] When the medium type indicates that the suction medium is blood, the valve in the air pressure state conversion module is in a closed state to intermittently suction the blood at a preset frequency;

[0010] When the medium type indicates that the suction medium includes a target volume of thrombus, a target frequency corresponding to the target volume is determined, and while maintaining suction, the valve in the air pressure state conversion module is opened and closed multiple times according to the target frequency, so that the air pressure state in the suction catheter switches back and forth between positive pressure and negative pressure according to the target frequency.

[0011] In one embodiment, the target volume includes a volume in a first volume range or a volume in a second volume range, and the first volume range is smaller than the second volume range;

[0012] Indicating that the aspirated medium includes a target volume of thrombus in the medium type, determining a target frequency corresponding to the target volume comprises:

[0013] If the medium type indicates that the aspirated medium includes a thrombus with a volume within the first volume range, taking a first frequency corresponding to the first volume as a target frequency;

[0014] If the medium type indicates that the aspirated medium includes a thrombus with a volume within the second volume range, taking a second frequency corresponding to the first volume as a target frequency;

[0015] The first frequency is smaller than the second frequency.

[0016] In one embodiment, the intelligent control module is further configured to execute:

[0017] determining a first force generated when a thrombus of various target volumes blocks a blood vessel;

[0018] Determine the second force generated in the blood vessel by the valve of the air pressure state conversion module when it is opened and closed at multiple frequencies, and obtain the allowed application time of each second force;

[0019] According to the first force, the second force and the allowed application time of the second force, target frequencies corresponding to thrombi of various target volumes are matched; the target frequencies include the first frequency and the second frequency.

[0020] In one embodiment, determining the medium type corresponding to the current suction medium of the suction catheter according to the pressure difference change rate and the flow rate change rate includes:

[0021] Identifying the current suction medium of the suction catheter according to the pressure difference change rate to obtain a first medium type identification result;

[0022] According to the flow rate change rate, the current suction medium of the suction catheter is identified to obtain a second medium type identification result;

[0023] When the medium types indicated by the first medium type identification result and the second medium type identification result are the same, the medium type corresponding to the current suction medium of the suction catheter is obtained.

[0024] In one embodiment, the current suction medium of the suction catheter is identified according to the pressure difference change rate to obtain a first medium type identification result, including:

[0025] Acquire a trained first medium type recognition model; the first medium type recognition model is obtained by supervised training of a neural network model based on a plurality of pressure difference change rate samples carrying medium type labels;

[0026] Inputting the pressure difference change rate into the first medium type identification model to obtain a first medium type identification result output by the model;

[0027] The step of identifying the current suction medium of the suction catheter according to the flow rate change rate to obtain a second medium type identification result includes:

[0028] Acquire a trained second medium type recognition model; the second medium type recognition model is obtained by supervised training of a neural network model based on a plurality of flow rate change samples carrying medium type labels;

[0029] The flow rate change rate is input into the second medium type identification model to obtain a second medium type identification result output by the model.

[0030] In one embodiment, the intelligent control module performs negative pressure suction on the medium in the suction catheter during the suction process; the intelligent control module is further configured to execute:

[0031] determining the total amount of blood aspirated based on flow data collected by a flow sensor for monitoring the flow of the aspiration catheter;

[0032] When the total amount of blood pumped reaches a first threshold, the negative pressure pumping of the medium in the pumping tube is stopped.

[0033] In one embodiment, the system also includes a manual control module for manually controlling the suction process; the manual control module, the air pressure state conversion module and the intelligent control module are respectively provided with lumens, and the suction catheter is sequentially connected to the manual control module, the air pressure state conversion module and the intelligent control module through the lumen, the manual control module is at the proximal end of the suction inlet, and the intelligent control module is at the distal end of the suction inlet.

[0034] In one embodiment, the intelligent control module is provided with an indicator light prompt unit, and the intelligent control module is further configured to execute:

[0035] After determining the medium type corresponding to the current suction medium of the suction catheter, obtaining the indicator light control mode corresponding to the medium type; the indicator light control mode for each medium type is different;

[0036] According to the indicator light lighting control method, the indicator light prompt unit is controlled to light up.

[0037] In one embodiment, the intelligent control module is provided with a sound prompt unit, and the intelligent control module is further configured to execute:

[0038] determining the total amount of blood aspirated based on flow data collected by a flow sensor for monitoring the flow of the aspiration catheter;

[0039] When the total amount of blood drawn reaches a second threshold, the sound prompt unit is controlled to play a prompt sound according to a corresponding prompt sound playing mode.

[0040] In a second aspect, the present application further provides a control method for a thrombus aspiration system, the system comprising an air pressure state conversion module, an intelligent control module and an aspiration catheter, wherein a first pressure sensor and a second pressure sensor are respectively provided at a proximal end of the aspiration catheter close to the aspiration inlet and a distal end away from the aspiration inlet; the method is applied to the intelligent control module, comprising:

[0041] During the suction process, the pressure difference between the proximal end and the distal end is determined based on the pressure data collected by the first pressure sensor and the pressure data collected by the second pressure sensor, and the pressure difference change rate of the pressure difference is determined; and the flow change rate of the blood flow in the suction catheter is determined based on the flow data collected by the flow sensor for monitoring the flow of the suction catheter;

[0042] Determining a medium type corresponding to a current suction medium of the suction conduit according to the pressure difference change rate and the flow rate change rate;

[0043] When the medium type indicates that the suction medium is blood, the valve in the air pressure state conversion module is in a closed state to intermittently suction the blood at a preset frequency;

[0044] When the medium type indicates that the suction medium includes a target volume of thrombus, a target frequency corresponding to the target volume is determined, and while maintaining suction, the valve in the air pressure state conversion module is opened and closed multiple times according to the target frequency, so that the air pressure state in the suction catheter switches back and forth between positive pressure and negative pressure according to the target frequency.

[0045] In the above-mentioned thrombus aspiration system and control method of the thrombus aspiration system, the intelligent control module can determine the pressure difference between the proximal end and the distal end during the aspiration process, and determine the pressure difference change rate of the pressure difference based on the pressure data collected by the first pressure sensor and the pressure data collected by the second pressure sensor, and determine the flow change rate of the blood flow in the aspiration catheter based on the flow data collected by the flow sensor used to monitor the flow of the aspiration catheter; then, the medium type corresponding to the current aspiration medium of the aspiration catheter can be determined based on the pressure difference change rate and the flow change rate; when the medium type indicates that the aspiration medium is blood, the blood is intermittently aspirated at a preset frequency when the valve in the air pressure state conversion module is in a closed state; when the medium type indicates that the aspiration medium includes a target volume of thrombus, the target frequency corresponding to the target volume is determined, and the valve in the air pressure state conversion module is controlled to be opened and closed multiple times according to the target frequency while maintaining the aspiration, so that the air pressure state in the aspiration catheter can be switched back and forth between positive pressure and negative pressure according to the target frequency. In the present embodiment, on the one hand, intermittent suction can be performed when the suction medium is blood, thereby reducing the amount of blood loss during the thrombus suction process; on the other hand, by controlling the valve in the air pressure state conversion module to open and close according to the target frequency, it is possible to provide the suction catheter with a suction force that can destroy the fatigue stress inside the thrombus when the vacuum pump suction capacity is limited, thereby improving the thrombus suction efficiency; on the other hand, by selecting the corresponding target frequency according to the volume of the thrombus and controlling the opening and closing of the valve according to the frequency, it is possible to reduce the impact of the switching of the positive and negative pressure states on the blood vessels while destroying the fatigue stress of the blocked thrombus as quickly as possible, thereby reducing the negative impact on the target object, thereby improving the suction safety while increasing the thrombus suction speed, and significantly improving the thrombus suction efficiency and the recanalization rate of the blood vessels. BRIEF DESCRIPTION OF THE DRAWINGS

[0046] In order to more clearly illustrate the technical solutions in the embodiments of the present application or related technologies, the drawings required for use in the embodiments of the present application or related technical descriptions will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0047] Figure 1 is a schematic structural diagram of a thrombus aspiration system in one embodiment;

[0048] Figure 2 It is a schematic flow chart of a control method of a thrombus aspiration system in one embodiment;

[0049] Figure 3a A schematic diagram of changes in pressure data under different suction media in one embodiment;

[0050] Figure 3b A schematic diagram of a change in pressure ratio under different suction media in one embodiment;

[0051] Figure 4a is a schematic structural diagram of an air pressure state conversion module in one embodiment;

[0052] Figure 4b A schematic diagram of the structure of an intelligent control module in an embodiment;

[0053] Figure 5 is a schematic structural diagram of another thrombus aspiration system in one embodiment;

[0054] Figure 6a is a front view of a manual control module in one embodiment;

[0055] Figure 6b is a top view of a manual control module in one embodiment;

[0056] Figure 7 is a structural block diagram of a control device of a thrombus aspiration system in one embodiment;

[0057] Figure 8 The figure is a diagram of the internal structure of a computer device in one embodiment. DETAILED DESCRIPTION

[0058] In order to make the purpose, technical solution and advantages of the present application more clearly understood, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0059] In order to enable those skilled in the art to better understand the present application, the relevant technology is first introduced below.

[0060] Driven by factors such as the increasing aging population, frequent cardiovascular diseases, unhealthy lifestyles (such as long-term sitting, high-fat diet, etc.), and the increasing proportion of obese people, the incidence of peripheral vascular diseases such as peripheral atherosclerosis and deep vein thrombosis is also increasing. The thrombi formed during the onset of the disease often hinder the normal flow of blood, affect the blood supply and oxygen supply to the organs, and then trigger a series of pathological and physiological changes. In traditional thrombosis treatment, drug thrombolysis or surgical thrombectomy can be performed. However, drug thrombolysis has certain limitations. Drug thrombolysis may have the risk of bleeding, and the dissolution effect on some large thrombi is not good, and the thrombolysis time window is limited; surgical thrombectomy is more traumatic, requires higher physical conditions, and has slow postoperative recovery and relatively more complications. In order to provide a more accurate, efficient and safe means of thrombosis treatment, thrombus aspiration came into being.

[0061] Early suction devices were relatively simple and had a single function. In some cases, suction was performed directly with a syringe. With the development of medical technology, the design of suction devices has been continuously optimized. For example, the diameter of the suction catheter is thinner and more flexible, which can reach more complex blood vessels. At the same time, the negative pressure provided by the suction device is also increasing, which can use greater suction force to suction thrombus.

[0062] In the related art, the suction device includes a thrombus suction negative pressure suction pump, which generates negative pressure to suction thrombus. Specifically, the thrombus suction negative pressure suction pump includes a vacuum pump, a pressure regulating valve, a negative pressure gauge, a collection bottle, etc. It generates a negative pressure source through the vacuum pump, and then adjusts the negative pressure to the target pressure through the pressure regulating valve. The pointer of the negative pressure gauge displays the current negative pressure value, which is connected to a disposable collection bottle through a pipeline, and then connected to a disposable suction connection tube and a suction catheter, thereby achieving suction of thrombus in the blood vessel.

[0063] At present, the negative pressure of common vacuum pumps can reach about 98Kpa, which is close to vacuum and cannot significantly improve performance. When there is a harder thrombus in the target object's body, the suction equipment cannot efficiently complete the thrombus suction.

[0064] Based on this, it is necessary to provide a thrombus aspiration system and a control method for the thrombus aspiration system for the above technical problems. The thrombus aspiration system and a control method for the thrombus aspiration system provided in this application can be applied to medical equipment (devices), medical interventional treatment and other related technical fields, involving multiple cross-fields such as biomedical engineering and materials science.

[0065] In one embodiment, Figure 1 As shown, a thrombus aspiration system is provided, which includes an air pressure state conversion module, an intelligent control module and a suction catheter. The air pressure state conversion module can also be called a vacuum conversion module, which can be used to convert the air pressure state in the suction catheter, for example, the air pressure state in the suction catheter can be converted between positive pressure and negative pressure. The suction catheter is provided with a suction inlet, through which the target object can be suctioned, and the suction medium obtained by suction is guided out of the body through the suction outlet of the suction catheter. The suction catheter is provided with corresponding pressure sensors at the proximal end close to the suction inlet and the distal end away from the suction inlet, respectively. For the convenience of distinction, the pressure sensor provided at the proximal end of the suction inlet is referred to as the first pressure sensor, and the pressure sensor provided at the distal end of the suction inlet is referred to as the second pressure sensor. In some examples, the first pressure sensor may be one or more, and the second pressure sensor may be one or more.

[0066] In this embodiment, if Figure 2 As shown, the intelligent control module is configured to perform the following steps:

[0067] S201, during the suction process, the pressure difference between the proximal end and the distal end is determined based on the pressure data collected by the first pressure sensor and the pressure data collected by the second pressure sensor, and the pressure difference change rate of the pressure difference is determined, and the flow change rate of the blood flow in the suction catheter is determined based on the flow data collected by the flow sensor used to monitor the flow of the suction catheter.

[0068] The aspiration process may be a process from the start of aspiration to the end of aspiration, or may be another time interval specified by the user when aspirating the thrombus.

[0069] In a specific implementation, the suction catheter may include one or more types of suction media, such as blood, thrombus, etc. Since there are differences in the fluidity of the suction medium and the difficulty of suction, a sensor can be set to monitor the suction catheter during the suction process. Specifically, the pressure of the suction catheter can be monitored by the first sensor and the second sensor, and the flow rate in the suction catheter can be monitored by setting a flow sensor, so as to obtain real-time pressure data and flow rate data during the suction process. When the suction medium changes, the pressure inside the suction catheter will also change. For example, Figure 3a The diagram shows the change of pressure recorded by the pressure sensors at the catheter end and the device end under different media, where the horizontal axis is the serial number of the data recorded by the pressure sensor and the vertical axis is the pressure. The data is obtained by testing when the valve in the air pressure state conversion module is in the closed state. During the test, when the medium in the suction catheter changes in order of air, water and blockage, as shown in Figure 3a As shown, the pressure in the suction catheter also continues to rise; Figure 3b It shows the pressure ratio of the pressure data collected by the two sensors at the catheter end and the equipment end when the medium in the suction catheter changes in sequence from air, water to blockage. The pressure ratio is the ratio of the pressure data collected by the two pressure sensors at the same time.

[0070] In this embodiment, during the suction process, on the one hand, the pressure difference between the proximal end and the distal end can be determined based on the pressure data collected by the first pressure sensor and the pressure data collected by the second pressure sensor, and the pressure difference change rate corresponding to the pressure difference can be calculated by determining multiple pressure differences obtained at different time points; on the other hand, the flow change rate of the blood flow in the suction catheter can be determined based on the flow data collected by the flow sensor used to monitor the flow of the suction catheter. In some examples, the flow sensor can be one or more, and the flow sensor can be set in the air pressure state conversion module or in the intelligent control module.

[0071] In some exemplary embodiments, the air pressure state conversion module may be located at the proximal end of the suction inlet, and the intelligent control module may be located at the distal end of the suction inlet. Accordingly, the first pressure sensor may be disposed in the air pressure state conversion module, and the second pressure sensor may be disposed in the intelligent control module.

[0072] For example, Figure 4a and Figure 4b The structures of the air pressure state conversion module and the intelligent control module are shown as examples. Figure 4a As shown, the air pressure state conversion module may include a physiological saline connection pipeline, a control mainboard, a solenoid valve, a liquid pipeline, an electric wire pipeline, a 3-way connector, a flow sensor and a first pressure sensor ( Figure 4a (not shown); wherein the solenoid valve is respectively connected to the pipeline of the suction catheter and the external saline pipeline (accessed through the saline connection pipeline), and the intelligent control module can control the intermittent opening and closing of the solenoid valve in the air pressure state conversion module, so that the entire suction catheter can be switched at a specific frequency in the vacuum environment and the atmospheric environment during the suction process. Figure 4b As shown, the intelligent control module includes a control main board, an indicator light strip, an electrical wire duct, a liquid duct, a three-way connector, a solenoid valve, and a disposable collection bottle connection end. The chip on the control main board has an embedded thrombus aspiration algorithm, which enables the intelligent control module to execute the control processing steps in the embodiments of the present application. In some embodiments, a flow sensor may also be provided in the intelligent control module.

[0073] S202: Determine the medium type corresponding to the current suction medium of the suction catheter according to the pressure difference change rate and the flow rate change rate.

[0074] When the suction medium in the suction catheter changes, for example, from suctioning blood to suction medium or from suctioning large thrombus to suctioning blood and then to suctioning medium thrombus, the pressure difference change rate and flow change rate in the suction catheter will also change accordingly. In this regard, in this embodiment, the pressure difference change rate and flow change rate can be combined at the same time to identify the medium type corresponding to the current suction medium of the suction catheter, wherein the medium type can indicate the type of the current suction medium. In this embodiment, the medium type can include two major categories: blood and thrombus. For thrombus, the embodiment of the present application further classifies the thrombus according to the volume of the thrombus to obtain thrombus of different volumes, such as large thrombus, medium thrombus, etc.

[0075] S203, when the medium type indicates that the pumping medium is blood, the blood is intermittently pumped at a preset frequency while the valve in the air pressure state conversion module is in a closed state.

[0076] One side of the valve is connected to the suction conduit, and the other side is connected to the atmosphere.

[0077] In actual application, when the medium type indicates that the suction medium is blood, the valve in the air pressure state conversion module can be closed to make the valve in a closed state. When the valve in the air pressure state conversion module is closed, the suction catheter can continuously suction the medium in the suction catheter. Compared with the continuous suction of blood in the related art, the blood can be intermittently suctioned at a preset frequency in this embodiment. For example, the blood can be sucked for 1S at a frequency of 0.5HZ and stopped for 1S. The intermittent suction at this time can minimize the patient's blood loss during surgery and reduce the blood that comes with the suction of thrombus. Ultimately, the thrombus in the blood can be sucked out and the target object's blood loss during surgery can be minimized.

[0078] S204, when the medium type indicates that the suction medium is a target volume of thrombus, a target frequency corresponding to the target volume is determined, and while maintaining suction, the valve in the air pressure state conversion module is opened and closed multiple times according to the target frequency, so that the air pressure state in the suction catheter switches back and forth between positive pressure and negative pressure according to the target frequency.

[0079] In the specific implementation, the difficulty of aspirating thrombi of different volumes varies. For example, the volume and hardness of thrombi will affect the difficulty of aspiration. For example, when the aspiration catheter encounters a harder thrombus or a thrombus that adheres to the blood vessel wall, the difficulty of aspiration will be greater. In the related art, aspiration is performed solely by relying on the negative pressure extraction capability of a vacuum pump. There are situations where the aspiration capacity is insufficient and the aspiration flow rate is large. For example, when the aspiration capacity is insufficient, it may be necessary to aspirate the thrombus by extending the aspiration time, which results in a significant increase in the amount of blood loss of the target object, for example, up to 200 ml. In even worse cases, the amount of blood loss can reach more than 300 ml, significantly increasing the risk of complications and causing great inconvenience to the recovery and treatment of the target object.

[0080] In this regard, when the medium type indicates that the suction medium is a thrombus of a target volume, the present embodiment can determine a target frequency corresponding to the target frequency, wherein the target frequency is used to control the switching frequency of the air pressure state in the suction catheter by the air pressure state conversion module. Specifically, when the present embodiment determines that the suction medium is a thrombus of a target volume, a target frequency corresponding to the target volume can be determined from a plurality of candidate frequencies. In some examples, the target frequency can be positively correlated with the target volume, that is, as the target volume of the thrombus increases, the target frequency also increases accordingly.

[0081] In addition, a valve is provided in the air pressure state conversion module. In some examples, the valve is a solenoid valve that can be opened and closed periodically and intermittently according to the set target frequency. Among them, one side of the solenoid valve of the air pressure state conversion module is connected to the external air pressure, for example, the solenoid valve can be connected to the pipeline system and the external physiological saline; the other side of the solenoid valve is connected to the suction catheter. Furthermore, during the suction process, when the valve in the air pressure state conversion module is opened, the pipeline system (such as the suction catheter) filled with negative pressure is connected to the outside world. At this time, the negative pressure state in the pipeline system is destroyed, and the suction catheter inlet loses the suction force. When the valve in the air pressure state conversion module is closed, the suction catheter inlet regains the suction force. By opening and closing the valve back and forth, the suction catheter can be switched back and forth between the reciprocating vacuum breaking and vacuum restoration states, thereby destroying the fatigue stress of the blocked thrombus, and also works on thrombus with a certain hardness, which can significantly improve the suction efficiency of thrombus.

[0082] Furthermore, after determining the target frequency, the valve in the air pressure state conversion module can be opened and closed multiple times according to the target frequency while continuing to perform suction, so that the air pressure state in the suction catheter switches back and forth between positive pressure and negative pressure according to the target frequency. When switching positive and negative pressures at different frequencies, different forces are generated in the suction catheter, and the force generated by high-frequency switching is greater than the force generated by low-frequency switching. In the embodiment of the present application, for thrombi of different volumes, by setting different frequencies respectively and selecting the appropriate frequency to open and close the valve in the air pressure state conversion module according to the volume corresponding to the currently detected thrombus, it is possible to destroy the fatigue stress of the blocked thrombus as quickly as possible while reducing the impact of the switching of positive and negative pressure states on the blood vessels and reducing damage to the target object.

[0083] It is understandable that the identification of the medium type and the determination of the target frequency can be a dynamic process, that is, the medium type corresponding to the suction medium currently being sucked is continuously identified during the suction process. When a change in the medium type is detected, the target frequency can be adjusted in time to dynamically adjust the suction method. Compared with continuous suction in the same manner, this embodiment monitors the real-time data inside the suction pipeline through a sensor, controls the valve to open and close intermittently, and suctions, which can greatly reduce the blood loss of the target object and reduce the postoperative complications of the target object.

[0084] The above-mentioned thrombus aspiration system may include an air pressure state conversion module, an intelligent control module and an aspiration catheter, wherein the proximal end of the aspiration catheter close to the aspiration inlet and the distal end away from the aspiration inlet are respectively provided with a first pressure sensor and a second pressure sensor; the intelligent control module may determine the pressure difference between the proximal end and the distal end, and determine the pressure difference change rate of the pressure difference according to the pressure data collected by the first pressure sensor and the pressure data collected by the second pressure sensor during the aspiration process, and determine the flow change rate of the blood flow in the aspiration catheter according to the flow data collected by the flow sensor for monitoring the flow of the aspiration catheter; then, the medium type corresponding to the current aspiration medium of the aspiration catheter may be determined according to the pressure difference change rate and the flow change rate; when the medium type indicates that the aspiration medium is blood, the valve in the air pressure state conversion module is in a closed state and the blood is intermittently aspirated according to a preset frequency; when the medium type indicates that the aspiration medium includes a target volume of thrombus, a target frequency corresponding to the target volume is determined, and the valve in the air pressure state conversion module is controlled to be opened and closed multiple times according to the target frequency while maintaining the aspiration, so that the air pressure state in the aspiration catheter can be switched back and forth between positive pressure and negative pressure according to the target frequency. In the present embodiment, on the one hand, intermittent suction can be performed when the suction medium is blood, thereby reducing the amount of blood loss during the thrombus suction process; on the other hand, by controlling the valve in the air pressure state conversion module to open and close according to the target frequency, it is possible to provide the suction catheter with a suction force that can destroy the fatigue stress inside the thrombus when the vacuum pump suction capacity is limited, thereby improving the thrombus suction efficiency; on the other hand, by selecting the corresponding target frequency according to the volume of the thrombus and controlling the opening and closing of the valve according to the frequency, it is possible to reduce the impact of the switching of the positive and negative pressure states on the blood vessels while destroying the fatigue stress of the blocked thrombus as quickly as possible, thereby reducing the negative impact on the target object, thereby improving the suction safety while increasing the thrombus suction speed, and significantly improving the thrombus suction efficiency and the recanalization rate of the blood vessels.

[0085] In an exemplary embodiment, the target volume includes a volume in a first volume range or a volume in a second volume range, wherein the first volume range is smaller than the second volume range. For example, a thrombus may be classified into a medium thrombus and a large thrombus, wherein the volume of the medium thrombus is within the first volume range and the volume of the large thrombus is within the second volume range.

[0086] Accordingly, in step S201, when the medium type indicates that the aspirated medium is a thrombus of a target volume, determining a target frequency corresponding to the target volume may include the following steps:

[0087] If the medium type indicates that the aspirated medium includes a thrombus with a volume within a first volume range, the first frequency corresponding to the first volume is used as the target frequency; if the medium type indicates that the aspirated medium includes a thrombus with a volume within a second volume range, the second frequency corresponding to the first volume is used as the target frequency; wherein the first frequency is less than the second frequency.

[0088] In practical applications, when the volume of the thrombus is small, it can be aspirated at a smaller frequency, and when the volume of the thrombus is large, it can be aspirated at a larger frequency, so that the fatigue stress of the blocked thrombus can be destroyed in a gentle manner when the thrombus volume is small, reducing the negative impact on the target object's blood vessels, and when the thrombus volume is large, the fatigue stress of the blocked thrombus can be destroyed in a rapid manner to reduce the blood loss of the target object. For the sake of distinction, the smaller frequency is called the first frequency, and the larger frequency is called the second frequency.

[0089] For example, when it is determined that the medium type of the suction medium is a medium-sized thrombus, the solenoid valve in the intelligent control module continues to remain open to suction the thrombus with the maximum negative pressure, and at the same time, the solenoid valve in the vacuum conversion module opens and closes at a frequency of 2HZ, that is, the valve opens for 0.25S and closes for 0.25S, thereby expelling the thrombus from the body; when it is determined that the medium type of the suction medium is a large thrombus, especially when the thrombus blocks the catheter and the thrombus cannot be smoothly suctioned out, the solenoid valve in the intelligent control module continues to remain open to suction the thrombus with the maximum negative pressure, and at the same time, the solenoid valve in the vacuum conversion module opens and closes at a frequency of 4HZ, that is, the valve opens for 0.125S and closes for 0.125S, thereby expelling the thrombus from the body. It is understandable that in practice, a variety of different frequencies can be configured for suction according to the type of suction. For example, when the medium type of the suction medium is determined to be blood or a small thrombus (such as blood or a mixture of blood and a small thrombus), the solenoid valve in the vacuum conversion module remains closed, and the solenoid valve in the intelligent control module is opened and closed at a frequency of 0.5HZ, that is, the valve is opened for 1S and closed for 1S. At this time, intermittent suction can minimize the patient's blood loss during surgery. The embodiment of the present application adjusts the frequency or flow of negative pressure suction in the suction pipeline through the valve in the intelligent control module to perform intermittent suction, which can reduce the blood that comes with the suction of thrombus, and ultimately can both suck out the thrombus in the blood and minimize the target object's blood loss during surgery.

[0090] In an exemplary embodiment, the intelligent control module is further configured to perform the following steps:

[0091] Determine the first force generated when blood clots of various target volumes block blood vessels; determine the second force generated in the blood vessels when the valve of the air pressure state conversion module is opened and closed at multiple frequencies, and obtain the allowed application time of each second force; match the target frequencies corresponding to blood clots of various target volumes based on the first force, the second force and the allowed application time of the second force.

[0092] The target frequency includes a first frequency and a second frequency.

[0093] In a specific implementation, the effect of the thrombus volume on the blood vessel can be predetermined. The thrombus will affect the degree of blocking the blood vessel at different target volumes, thereby generating different physical forces. For the sake of distinction, the physical force is referred to as the first force; in some examples, the first force may include the pressure of the thrombus on the blood vessel wall, the degree of blood flow obstruction, etc. In some examples, the first force at multiple target volumes can be calculated through clinical data or simulation experiments (such as simulation software testing).

[0094] On the other hand, the air pressure state conversion module changes the air pressure state in the suction catheter by opening and closing the valve, thereby pushing or moving the thrombus. The opening and closing frequency of the valve will affect the speed and intensity of the air pressure change, thereby generating different forces in the blood vessels. For the sake of distinction, this force is called the second force. At the same time, different second forces may have different effects on the target object. For this reason, simulation experiments can be used to determine the safe and effective application time of each second force.

[0095] Furthermore, after determining the first force generated by the thrombus and the second force generated by the air pressure state conversion module and their allowed application time, the first force can be matched with each second force and its corresponding allowed application frequency. The goal is to adjust the opening and closing frequency of the valve so that the second force can destroy or offset the first force, thereby promptly and quickly destroying the fatigue stress of the blocked thrombus, while ensuring that this treatment is carried out within a safe time range.

[0096] In this embodiment, by matching the target frequencies corresponding to thrombi of various target volumes according to the first force, the second force and the allowed application time of the second force, it can be ensured that the intelligent control module effectively takes into account both suction efficiency and suction safety when controlling the opening and closing of the valve.

[0097] In an exemplary embodiment, in step S202, determining the medium type corresponding to the current suction medium of the suction catheter according to the pressure difference change rate and the flow rate change rate may include the following steps:

[0098] According to the pressure difference change rate, the current suction medium of the suction catheter is identified to obtain a first medium type identification result; according to the flow change rate, the current suction medium of the suction catheter is identified to obtain a second medium type identification result; when the medium types indicated by the first medium type identification result and the second medium type identification result are the same, the medium type corresponding to the current suction medium of the suction catheter is obtained.

[0099] In a specific implementation, the suction medium can be identified based on the pressure difference change rate and the flow rate change rate, respectively. In other words, in this embodiment, on the one hand, the current suction medium of the suction catheter can be identified based on one or more pressure difference change rates to obtain a corresponding medium type identification result. On the other hand, the current suction medium of the suction catheter can be identified based on one or more flow rate change rates to obtain a corresponding medium type identification result. For ease of distinction, the medium type identification result obtained based on the pressure difference change rate is referred to as the first medium type identification result, and the medium type identification result obtained based on the flow rate change rate is referred to as the second medium type identification result.

[0100] After obtaining the first medium type identification result and the second medium type identification result, it can be determined whether the medium types indicated by the two results are the same. If so, the medium type corresponding to the current suction medium of the suction catheter can be obtained, for example, the medium type indicated by the first medium type identification result or the second medium type identification result is used as the currently identified medium type. If not, it can be determined that the medium type has not been identified, and identification can be continued according to the pressure difference change rate and the flow rate change rate until the medium types indicated by the two results are the same.

[0101] In this embodiment, by performing medium type identification according to the pressure difference change rate and the flow rate change rate respectively, and when the medium types indicated by the first medium type identification result and the second medium type identification result are the same, the medium type corresponding to the current suction medium of the suction catheter is obtained, and the medium type identification results can be cross-checked through multiple media identification methods, which helps to more accurately identify the inhaled medium and reduce misjudgment.

[0102] In some exemplary embodiments, when the current suction medium of the suction catheter is identified according to the pressure difference change rate and the flow rate change rate, the pressure difference change rate can be compared with the corresponding preset threshold value, and the flow rate change rate can be compared with the corresponding preset threshold value, and the medium type identification result can be determined according to the comparison result. However, in practice, the pressure difference change and flow rate change of the suction catheter may be complex and diverse.

[0103] In this regard, in other exemplary embodiments, the current suction medium of the suction catheter is identified based on the pressure difference change rate to obtain a first medium type identification result, which may include the following steps: obtaining a trained first medium type identification model; the first medium type identification model is obtained by supervised training of a neural network model based on multiple pressure difference change rate samples carrying medium type labels; the pressure difference change rate is input into the first medium type identification model to obtain the first medium type identification result output by the model.

[0104] According to the flow change rate, the current suction medium of the suction catheter is identified to obtain a second medium type identification result, which can include the following steps: obtaining a trained second medium type identification model; the second medium type identification model is obtained by supervised training of a neural network model based on multiple flow change rate samples carrying medium type labels; the flow change rate is input into the second medium type identification model to obtain the second medium type identification result output by the model.

[0105] In a specific implementation, two medium type recognition models can be pre-trained, one medium type recognition model is used to identify the suction medium in the suction duct based on the pressure difference change rate alone, and the other medium type recognition model is used to identify the suction medium in the suction duct based on the flow rate change rate alone. For ease of distinction, the model for identifying the suction medium based on the pressure difference change rate is called the first medium type recognition model, and the model for identifying the suction medium based on the flow rate change rate is called the second medium type recognition model.

[0106] Specifically, on the one hand, a plurality of pressure differential change rate samples carrying medium type labels can be used to perform supervised training on the neural network model, wherein each pressure differential change rate sample may include one pressure differential change rate or multiple pressure differential change rates (such as multiple pressure differential change rate sequences that characterize the change of the pressure differential change rate over time), and each pressure differential change rate sample carries a corresponding medium type label, which is used to indicate the type of suction medium in the suction catheter at the corresponding pressure differential change rate. By using a plurality of pressure differential change rate samples to perform supervised training on the neural network model until the training end condition is met, the model can learn the mapping relationship between multiple pressure differential change rates and suction medium types, and then the first medium type recognition model obtained through training can more accurately identify the suction medium type according to the pressure differential change rate. On the other hand, the neural network model can be supervised and trained using multiple flow change rate samples carrying medium type labels, wherein each flow change rate sample may include one flow change rate or multiple flow change rates (such as multiple flow change rate sequences that characterize the flow change rate over time), and each flow change rate sample carries a corresponding medium type label for indicating the type of suction medium in the suction catheter at the corresponding flow change rate. By using multiple flow change rate samples to supervise and train the neural network model until the training end condition is met, the model can learn the mapping relationship between multiple flow change rates and suction medium types, and then the second medium type recognition model obtained through training can more accurately identify the suction medium type based on the flow change rate.

[0107] After the corresponding pressure difference change rate and flow rate change rate are obtained during the suction process, they are respectively input into the first medium type identification model and the second medium type identification model to obtain the first medium type identification result and the second medium type identification result output by the model.

[0108] In this embodiment, by pre-training the first medium type identification model and the second medium type identification model, and then having the two models output corresponding medium type identification results respectively, the model can more accurately identify the medium types corresponding to different pressure difference change rates and flow rate change rates based on the experience information learned from the samples in the past, thereby improving the accuracy of the medium identification results.

[0109] In an exemplary embodiment, the intelligent control module can perform negative pressure suction on the medium in the suction catheter during the suction process, for example Figure 3bAs shown, a disposable collecting bottle connection end may be provided in the intelligent control module, and the solenoid valve in the intelligent control module may be connected to the suction catheter at one side, and may be connected to the disposable collecting bottle connection end at the other side. During the suction process, the valve may be opened for negative pressure suction, or, when the suction medium is blood and / or small thrombus, the valve may be controlled to open and close according to a preset frequency (such as a frequency of 0.5 Hz), which helps to minimize blood loss through intermittent suction.

[0110] Furthermore, during the suction process, the intelligent control module can also be configured to perform the following steps:

[0111] The total amount of blood suction is determined according to the flow data collected by the flow sensor for monitoring the flow of the suction catheter; when the total amount of blood suction reaches a first threshold, the negative pressure suction of the medium in the suction catheter is stopped.

[0112] In a specific implementation, the flow sensor can be used to monitor the flow of the suction catheter. For example, the flow sensor can be set in the intelligent control module, or in the pressure state conversion module, or in both the intelligent control module and the pressure state conversion module. In the monitoring process, the intelligent control module can determine the total amount of blood suction based on the flow data collected by the flow sensor. When it is detected that the total amount of blood suction reaches a first threshold, the intelligent control module can control the stop of negative pressure suction of the medium in the suction catheter.

[0113] In the related art, thrombus aspiration has no passive safety protection, and the safety of the aspiration operation is highly dependent on the operation and monitoring of the operating user. Accordingly, when the target object loses too much blood, the aspiration can only be stopped manually by the doctor, which places high demands on the operating user. In comparison, this embodiment actively cuts off the negative pressure aspiration by the intelligent control module when the total amount of blood aspirated reaches a first threshold, which can effectively avoid the danger caused by excessive blood loss of the target object and ensure the safety of the target object during the aspiration process. The overall blood loss is controlled by the flow sensor, which can not only greatly improve the safety of the operation but also greatly reduce the difficulty of the surgical operation for the operating user, and is more friendly to both the target object and the operating user.

[0114] In an exemplary embodiment, the system may further include a manual control module for manually controlling the suction process, wherein the manual control module, the air pressure state conversion module and the intelligent control module are respectively provided with lumens, and the suction catheter is connected to the manual control module, the air pressure state conversion module and the intelligent control module in sequence through the lumens, the manual control module is at the proximal end of the suction inlet, and the intelligent control module is at the distal end of the suction inlet.

[0115] For example, Figure 5The intelligent automatic thrombus negative pressure aspiration system shown in the figure includes three modules, namely a manual control module, a vacuum conversion module and an intelligent control module. The three modules can be used together with a negative pressure aspiration pump and a thrombus aspiration catheter for thrombus aspiration. The three modules can be connected through a double-lumen tube, namely an intermediate connecting tube and a wire connecting tube. The intermediate connecting tube passes blood and thrombus mixture, and the wire connecting tube passes power lines and signal lines. The manual control module can be connected to the thrombus aspiration catheter through a Luer connector, and the intelligent control module is connected to the disposable collection bottle on the negative pressure aspiration pump through an interference fit. The wires of the intelligent control module are connected to the power output on the negative pressure aspiration pump. In some examples, the structure of the manual control module can be as follows: Figure 6a The main view and Figure 6b As shown in the top view of , the manual control module may include a liquid pipeline, an electric wire pipeline, a manual push block, a suction catheter connecting end, a pressure sensor (ie, a first pressure sensor) and a 3-way connector.

[0116] It can be understood that the manual control module can have the highest control authority, or the control authority of the manual control module can be higher than the control authority of the intelligent control module, so that the operating user can control the entire system and the start and end of the suction process through the manual control module. For example, the manual control module can be provided with a push block that can be used to trigger suction or stop suction. The operating user can activate the suction system by pushing the push block to open the main pipeline, and can also turn off the suction system by pushing back the push block. This helps to ensure the safety of the operation by turning off the push block and then turning off the suction in an emergency.

[0117] In an exemplary embodiment, the intelligent control module is provided with an indicator light prompt unit, for example Figure 3b The intelligent control module shown is provided with a warning light strip. Accordingly, the intelligent control module can also be configured to perform:

[0118] After determining the medium type corresponding to the current suction medium of the suction catheter, the indicator light control mode corresponding to the medium type is obtained; the indicator light control modes of different medium types are different; according to the indicator light control mode, the indicator light prompt unit is controlled to light up.

[0119] Specifically, since negative pressure suction pump products are non-sterile products and are noisy, in actual clinical operations, the relevant equipment is often placed on a trolley far away from the operator (such as the operating user). However, the standard negative pressure gauge is small (the diameter of the negative pressure gauge is about 40mm), and the current negative pressure value is displayed on the negative pressure gauge by a pointer. As a result, it is difficult for the operator to easily and quickly identify the indication numbers of the long-distance negative pressure gauge during the operation, and it is impossible to quickly operate according to the actual negative pressure size, causing inconvenience to the operator's operation.

[0120] In this regard, in this embodiment, after determining the medium type corresponding to the current suction medium of the suction catheter, the indicator light control method corresponding to the medium type can be obtained. Since the indicator light control methods of various medium types are different, by controlling the indicator light prompt unit to light up according to the indicator light control method, the operating user can remotely know the type of suction medium in the suction catheter, so that the operating user can focus more on the target object instead of always paying attention to the use status of the equipment, which helps to greatly reduce the difficulty of surgical operations and help shorten the operation time.

[0121] In an exemplary embodiment, the intelligent control module is provided with a sound prompt unit, and the intelligent control module is further configured to execute:

[0122] The total amount of blood aspirated is determined based on the flow data collected by the flow sensor for monitoring the flow of the aspiration catheter; when the total amount of blood aspirated reaches a second threshold, the sound prompt unit is controlled to play a prompt sound according to the corresponding prompt sound playing mode.

[0123] In a specific implementation, the intelligent control module can determine the total amount of blood drawn in real time based on the flow data, and judge whether the total amount of blood drawn has reached a second threshold value that may cause operational risks, wherein the second threshold value may be the same as or different from the first threshold value. When it is determined that the total amount of blood drawn has reached the second threshold value, the intelligent control module can control the sound prompt unit to play a prompt sound according to the corresponding prompt sound playing mode, so that the operating user can promptly discover that the current total amount of blood drawn may be large, and execute relevant risk prevention measures in advance.

[0124] For example, the intelligent control module can be provided with an indicator light strip and a prompt buzzer at the same time, which can provide light and sound prompts according to the status or results of the system operation. When the indicator light is solid green, it means that the device is powered on and ready; when the indicator light flashes green for 0.5S on and 0.5S off, it means that the device is operating normally and aspirating blood or a mixture of blood and small thrombi; when the indicator light flashes green for 1S on and 1S off, it means that the device is operating normally and aspirating medium-sized thrombi; when the indicator light flashes green for 2S on and 2S off, it means that the device is operating normally and aspirating large thrombi; when the indicator light flashes red, it means that the flow rate has reached 400ml, and the buzzer sounds an alarm; when the indicator light is solid red, it means that the device system has an error and needs to be checked or replaced.

[0125] It can be understood that the intelligent control module provides light indication and sound indication. When in different thrombus aspiration states, such as intermittent aspiration or continuous aspiration, the aspiration catheter contacts the thrombus or blood, and in different modes of the vacuum conversion module, the light and buzzer will present different states, such as always on or flashing at a certain frequency, short sound or sound of a certain frequency, etc. The remote operator can perform quick operations based on these real-time prompt information to improve the efficiency of the operation. The thrombus aspiration system provided in one or more embodiments of the present application can operate intelligently and automatically. The operating user only needs to operate the aspiration catheter for aspiration, without having to control the disposable suction connection tube to control the blood flow at all times; through light and sound prompts, the operating user can quickly and clearly receive information about the current operation status at a long distance, so that the operating user can focus more on the target object to improve the efficiency of the operation.

[0126] In one embodiment, the present application also provides a control method for a thrombus aspiration system, the system comprising an air pressure state conversion module, an intelligent control module and an aspiration catheter, wherein the aspiration catheter is provided with a first pressure sensor and a second pressure sensor at a proximal end close to the aspiration inlet and a distal end away from the aspiration inlet, respectively. The method can be applied to the intelligent control module, and the method may include the following steps:

[0127] S301, during the suction process, the pressure difference between the proximal end and the distal end is determined based on the pressure data collected by the first pressure sensor and the pressure data collected by the second pressure sensor, and the pressure difference change rate of the pressure difference is determined, and the flow change rate of the blood flow in the suction catheter is determined based on the flow data collected by the flow sensor used to monitor the flow of the suction catheter.

[0128] S302, determining the medium type corresponding to the current suction medium of the suction catheter according to the pressure difference change rate and the flow rate change rate;

[0129] S303, when the medium type indicates that the pumping medium is blood, the blood is intermittently pumped at a preset frequency while the valve in the air pressure state conversion module is in a closed state.

[0130] S304, when the medium type indicates that the suction medium includes a target volume of thrombus, a target frequency corresponding to the target volume is determined, and while maintaining suction, the valve in the air pressure state conversion module is opened and closed multiple times according to the target frequency, so that the air pressure state in the suction catheter switches back and forth between positive pressure and negative pressure according to the target frequency.

[0131] In one embodiment, the target volume includes a volume in a first volume range or a volume in a second volume range, the first volume range being smaller than the second volume range;

[0132] Indicating that the aspirated medium includes a target volume of thrombus in the medium type, determining a target frequency corresponding to the target volume comprises:

[0133] If the medium type indicates that the aspirated medium includes a thrombus with a volume within the first volume range, taking a first frequency corresponding to the first volume as a target frequency;

[0134] If the medium type indicates that the aspirated medium includes a thrombus with a volume within the second volume range, taking a second frequency corresponding to the first volume as a target frequency;

[0135] The first frequency is smaller than the second frequency.

[0136] In one embodiment, the method further comprises:

[0137] determining a first force generated when a thrombus of various target volumes blocks a blood vessel;

[0138] Determine the second force generated in the blood vessel by the valve of the air pressure state conversion module when it is opened and closed at multiple frequencies, and obtain the allowed application time of each second force;

[0139] According to the first force, the second force and the allowed application time of the second force, target frequencies corresponding to thrombi of various target volumes are matched; the target frequencies include the first frequency and the second frequency.

[0140] In one embodiment, determining the medium type corresponding to the current suction medium of the suction catheter according to the pressure difference change rate and the flow rate change rate includes:

[0141] Identifying the current suction medium of the suction catheter according to the pressure difference change rate to obtain a first medium type identification result;

[0142] According to the flow rate change rate, the current suction medium of the suction catheter is identified to obtain a second medium type identification result;

[0143] When the medium types indicated by the first medium type identification result and the second medium type identification result are the same, the medium type corresponding to the current suction medium of the suction catheter is obtained.

[0144] In one embodiment, the identifying of the current suction medium of the suction catheter according to the pressure difference change rate to obtain a first medium type identification result includes:

[0145] Acquire a trained first medium type recognition model; the first medium type recognition model is obtained by supervised training of a neural network model based on a plurality of pressure difference change rate samples carrying medium type labels;

[0146] Inputting the pressure difference change rate into the first medium type identification model to obtain a first medium type identification result output by the model;

[0147] The step of identifying the current suction medium of the suction catheter according to the flow rate change rate to obtain a second medium type identification result includes:

[0148] Acquire a trained second medium type recognition model; the second medium type recognition model is obtained by supervised training of a neural network model based on a plurality of flow rate change samples carrying medium type labels;

[0149] The flow rate change rate is input into the second medium type identification model to obtain a second medium type identification result output by the model.

[0150] In one embodiment, the intelligent control module performs negative pressure suction on the medium in the suction catheter during the suction process; the method further includes:

[0151] determining the total amount of blood aspirated based on flow data collected by a flow sensor for monitoring the flow of the aspiration catheter;

[0152] When the total amount of blood pumped reaches a first threshold, the negative pressure pumping of the medium in the pumping tube is stopped.

[0153] In one embodiment, the system also includes a manual control module for manually controlling the suction process; the manual control module, the air pressure state conversion module and the intelligent control module are respectively provided with lumens, and the suction catheter is connected to the manual control module, the air pressure state conversion module and the intelligent control module in sequence through the lumen, the manual control module is at the proximal end of the suction inlet, and the intelligent control module is at the distal end of the suction inlet.

[0154] In one embodiment, the intelligent control module is provided with an indicator light prompt unit, and the method further comprises:

[0155] After determining the medium type corresponding to the current suction medium of the suction catheter, obtaining the indicator light control mode corresponding to the medium type; the indicator light control mode for each medium type is different;

[0156] According to the indicator light lighting control method, the indicator light prompt unit is controlled to light up.

[0157] In one embodiment, the intelligent control module is provided with a sound prompt unit, and the method further comprises:

[0158] determining the total amount of blood aspirated based on flow data collected by a flow sensor for monitoring the flow of the aspiration catheter;

[0159] When the total amount of blood drawn reaches a second threshold, the sound prompt unit is controlled to play a prompt sound according to a corresponding prompt sound playing mode.

[0160] The specific implementation of the control method of the thrombus aspiration system in one or more of the above embodiments can refer to one or more of the above embodiments of the thrombus aspiration system and will not be described in detail here.

[0161] It should be understood that, although the various steps in the flowcharts involved in the above-mentioned embodiments are displayed in sequence according to the indication of the arrows, these steps are not necessarily executed in sequence according to the order indicated by the arrows. Unless there is a clear explanation in this article, the execution of these steps does not have a strict order restriction, and these steps can be executed in other orders. Moreover, at least a part of the steps in the flowcharts involved in the above-mentioned embodiments can include multiple steps or multiple stages, and these steps or stages are not necessarily executed at the same time, but can be executed at different times, and the execution order of these steps or stages is not necessarily to be carried out in sequence, but can be executed in turn or alternately with other steps or at least a part of the steps or stages in other steps.

[0162] Based on the same inventive concept, the embodiment of the present application also provides a control device for a thrombus aspiration system for implementing the control method of the thrombus aspiration system involved above. The implementation scheme for solving the problem provided by the device is similar to the implementation scheme recorded in the above method, so the specific limitations in the embodiments of the control device for one or more thrombus aspiration systems provided below can refer to the limitations of the control method for the thrombus aspiration system above, and will not be repeated here.

[0163] In an exemplary embodiment, Figure 7 As shown, a control device of a thrombus aspiration system is provided, the system comprises an air pressure state conversion module, an intelligent control module and an aspiration catheter, the aspiration catheter is provided with a first pressure sensor and a second pressure sensor at a proximal end close to the aspiration inlet and a distal end away from the aspiration inlet, respectively; the device is applied to the intelligent control module, and the device comprises:

[0164] A monitoring module 601 is used to determine the pressure difference between the proximal end and the distal end and the pressure difference change rate of the pressure difference according to the pressure data collected by the first pressure sensor and the pressure data collected by the second pressure sensor during the suction process, and to determine the flow change rate of the blood flow in the suction catheter according to the flow data collected by the flow sensor for monitoring the flow of the suction catheter;

[0165] A medium determination module 602, configured to determine a medium type corresponding to a current suction medium of the suction catheter according to the pressure difference change rate and the flow rate change rate;

[0166] A blood suction module 603, configured to intermittently suction the blood at a preset frequency when the medium type indicates that the suction medium is blood and the valve in the air pressure state conversion module is in a closed state;

[0167] The valve opening and closing module 604 is used to indicate that the suction medium includes a target volume of thrombus when the medium type indicates, determine the target frequency corresponding to the target volume, and open and close the valve in the air pressure state conversion module multiple times according to the target frequency while maintaining suction, so that the air pressure state in the suction catheter switches back and forth between positive pressure and negative pressure according to the target frequency.

[0168] In one embodiment, the target volume includes a volume in a first volume range or a volume in a second volume range, the first volume range being smaller than the second volume range;

[0169] The frequency determination module 602 is used to:

[0170] If the medium type indicates that the aspirated medium includes a thrombus with a volume within the first volume range, taking a first frequency corresponding to the first volume as a target frequency;

[0171] If the medium type indicates that the aspirated medium includes a thrombus with a volume within the second volume range, taking a second frequency corresponding to the first volume as a target frequency;

[0172] The first frequency is smaller than the second frequency.

[0173] In one embodiment, the device further comprises a frequency setting module, wherein the frequency setting module is configured to:

[0174] Determine the first force generated when a thrombus of various target volumes blocks a blood vessel;

[0175] Determine the second force generated in the blood vessel by the valve of the air pressure state conversion module when it is opened and closed at multiple frequencies, and obtain the allowed application time of each second force;

[0176] According to the first force, the second force and the allowed application time of the second force, target frequencies corresponding to thrombi of various target volumes are matched; the target frequencies include the first frequency and the second frequency.

[0177] In one embodiment, the frequency determination module 602 is used to:

[0178] Identifying the current suction medium of the suction catheter according to the pressure difference change rate to obtain a first medium type identification result;

[0179] According to the flow rate change rate, the current suction medium of the suction catheter is identified to obtain a second medium type identification result;

[0180] When the medium types indicated by the first medium type identification result and the second medium type identification result are the same, the medium type corresponding to the current suction medium of the suction catheter is obtained.

[0181] In one embodiment, the frequency determination module 602 is used to:

[0182] Acquire a trained first medium type recognition model; the first medium type recognition model is obtained by supervised training of a neural network model based on a plurality of pressure difference change rate samples carrying medium type labels;

[0183] Inputting the pressure difference change rate into the first medium type identification model to obtain a first medium type identification result output by the model;

[0184] Acquire a trained second medium type recognition model; the second medium type recognition model is obtained by supervised training of a neural network model based on a plurality of flow rate change samples carrying medium type labels;

[0185] The flow rate change rate is input into the second medium type identification model to obtain a second medium type identification result output by the model.

[0186] In one embodiment, the intelligent control module performs negative pressure suction on the medium in the suction catheter during the suction process; the device also includes a suction total amount monitoring module, and the suction total amount monitoring module is used to:

[0187] determining the total amount of blood aspirated based on flow data collected by a flow sensor for monitoring the flow of the aspiration catheter;

[0188] When the total amount of blood pumped reaches a first threshold, the negative pressure pumping of the medium in the pumping tube is stopped.

[0189] In one embodiment, the system also includes a manual control module for manually controlling the suction process; the manual control module, the air pressure state conversion module and the intelligent control module are respectively provided with lumens, and the suction catheter is connected to the manual control module, the air pressure state conversion module and the intelligent control module in sequence through the lumen, the manual control module is at the proximal end of the suction inlet, and the intelligent control module is at the distal end of the suction inlet.

[0190] In one embodiment, the intelligent control module is provided with an indicator light prompt unit, and the device further comprises a light prompt module, and the light prompt module is used to:

[0191] After determining the medium type corresponding to the current suction medium of the suction catheter, obtaining the indicator light control mode corresponding to the medium type; the indicator light control mode for each medium type is different;

[0192] According to the indicator light lighting control method, the indicator light prompt unit is controlled to light up.

[0193] In one embodiment, the intelligent control module is provided with a sound prompt unit, and the device further comprises a sound prompt module, and the sound prompt module is used to:

[0194] determining the total amount of blood aspirated based on flow data collected by a flow sensor for monitoring the flow of the aspiration catheter;

[0195] When the total amount of blood drawn reaches a second threshold, the sound prompt unit is controlled to play a prompt sound according to a corresponding prompt sound playing mode.

[0196] Each module in the control device of the above-mentioned thrombus aspiration system can be implemented in whole or in part by software, hardware or a combination thereof. Each of the above-mentioned modules can be embedded in or independent of the processor in the computer device in the form of hardware, or can be stored in the memory of the computer device in the form of software, so that the processor can call and execute the operations corresponding to each of the above modules.

[0197] In an exemplary embodiment, a computer device is provided. The computer device may be a terminal, and its internal structure diagram may be as shown in FIG. Figure 7As shown. The computer device includes a processor, a memory, an input / output interface, a communication interface, a display unit and an input device. The processor, the memory and the input / output interface are connected through a system bus, and the communication interface, the display unit and the input device are connected to the system bus through the input / output interface. The processor of the computer device is used to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of the operating system and the computer program in the non-volatile storage medium. The input / output interface of the computer device is used to exchange information between the processor and the external device. The communication interface of the computer device is used to communicate with an external terminal in a wired or wireless manner, and the wireless manner can be implemented through WIFI, a mobile cellular network, near field communication (NFC) or other technologies. When the computer program is executed by the processor, a control method of a thrombus aspiration system is implemented. The display unit of the computer device is used to form a visually visible picture, which can be a display screen, a projection device or a virtual reality imaging device. The display screen can be a liquid crystal display screen or an electronic ink display screen, and the input device of the computer device can be a touch layer covering the display screen, or a button, trackball or touchpad set on the computer device shell, or an external keyboard, touchpad or mouse.

[0198] Those skilled in the art will understand that Figure 7 The structure shown in the figure is only a block diagram of a part of the structure related to the solution of the present application, and does not constitute a limitation on the computer device to which the solution of the present application is applied. The specific computer device may include more or fewer components than those shown in the figure, or combine certain components, or have a different arrangement of components.

[0199] In one embodiment, a computer device is provided, including a memory and a processor, wherein a computer program is stored in the memory, and the processor implements the steps in the above-mentioned method embodiments when executing the computer program.

[0200] In one embodiment, a computer-readable storage medium is provided, on which a computer program is stored. When the computer program is executed by a processor, the steps in the above-mentioned method embodiments are implemented.

[0201] In one embodiment, a computer program product is provided, including a computer program, which implements the steps in the above method embodiments when executed by a processor.

[0202] It should be noted that the user information (including but not limited to user device information, user personal information, etc.) and data (including but not limited to data used for analysis, stored data, displayed data, etc.) involved in this application are all information and data authorized by the user or fully authorized by all parties, and the collection, use and processing of relevant data must comply with relevant regulations.

[0203] A person of ordinary skill in the art can understand that all or part of the processes in the above-mentioned embodiment method can be completed by instructing the relevant hardware through a computer program, and the computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above-mentioned methods. Among them, any reference to the memory, database or other medium used in the embodiments provided in the present application can include at least one of non-volatile memory and volatile memory. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetic random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory can include random access memory (RAM) or external cache memory, etc. As an illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM). The database involved in each embodiment provided in this application may include at least one of a relational database and a non-relational database. Non-relational databases may include distributed databases based on blockchains, etc., but are not limited to this. The processor involved in each embodiment provided in this application may be a general-purpose processor, a central processing unit, a graphics processor, a digital signal processor, a programmable logic device, a data processing logic device based on quantum computing, an artificial intelligence (AI) processor, etc., but are not limited to this.

[0204] The technical features of the above embodiments may be combined arbitrarily. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this application.

[0205] The above-described embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the present application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the present application shall be subject to the attached claims.

Claims

1. A thrombus aspiration system, characterized in that: The system comprises an air pressure state conversion module, an intelligent control module and a suction catheter, wherein a first pressure sensor and a second pressure sensor are respectively arranged at a proximal end of the suction catheter close to the suction inlet and a distal end away from the suction inlet; The intelligent control module is configured to perform: During the suction process, the pressure difference between the proximal end and the distal end is determined based on the pressure data collected by the first pressure sensor and the pressure data collected by the second pressure sensor, and the pressure difference change rate of the pressure difference is determined; and the flow change rate of the blood flow in the suction catheter is determined based on the flow data collected by the flow sensor for monitoring the flow of the suction catheter; Determining a medium type corresponding to a current suction medium of the suction conduit according to the pressure difference change rate and the flow rate change rate; When the medium type indicates that the suction medium is blood, the valve in the air pressure state conversion module is in a closed state to intermittently suction the blood at a preset frequency; When the medium type indicates that the suction medium includes a target volume of thrombus, a target frequency corresponding to the target volume of thrombus is determined, and while maintaining suction, the valve in the air pressure state conversion module is opened and closed multiple times according to the target frequency, so that the air pressure state in the suction catheter switches back and forth between positive pressure and negative pressure according to the target frequency.

2. The system according to claim 1, characterized in that The target volume of thrombus includes a thrombus with a volume in a first volume range or a thrombus with a volume in a second volume range, wherein the first volume range is smaller than the second volume range; When the medium type indicates that the aspirated medium includes a target volume of thrombus, determining a target frequency corresponding to the target volume of thrombus comprises: If the medium type indicates that the aspirated medium includes a thrombus with a volume within the first volume range, taking a first frequency corresponding to the first volume as a target frequency; If the medium type indicates that the aspirated medium includes a thrombus with a volume within the second volume range, taking a second frequency corresponding to the first volume as a target frequency; The first frequency is smaller than the second frequency.

3. The system according to claim 2, characterized in that The intelligent control module is further configured to execute: Determine the first force generated when a thrombus of various target volumes blocks a blood vessel; Determine the second force generated in the blood vessel by the valve of the air pressure state conversion module when it is opened and closed at multiple frequencies, and obtain the allowed application time of each second force; According to the first force, the second force and the allowed application time of the second force, target frequencies corresponding to thrombi of various target volumes are matched; the target frequencies include the first frequency and the second frequency.

4. The system according to claim 1, characterized in that Determining the medium type corresponding to the current suction medium of the suction catheter according to the pressure difference change rate and the flow rate change rate includes: Identifying the current suction medium of the suction catheter according to the pressure difference change rate to obtain a first medium type identification result; According to the flow rate change rate, the current suction medium of the suction catheter is identified to obtain a second medium type identification result; When the medium types indicated by the first medium type identification result and the second medium type identification result are the same, the medium type corresponding to the current suction medium of the suction catheter is obtained.

5. The system according to claim 4, characterized in that The step of identifying the current suction medium of the suction catheter according to the pressure difference change rate to obtain a first medium type identification result includes: Acquire a trained first medium type recognition model; the first medium type recognition model is obtained by supervised training of a neural network model based on a plurality of pressure difference change rate samples carrying medium type labels; Inputting the pressure difference change rate into the first medium type identification model to obtain a first medium type identification result output by the model; The step of identifying the current suction medium of the suction catheter according to the flow rate change rate to obtain a second medium type identification result includes: Acquire a trained second medium type recognition model; the second medium type recognition model is obtained by supervised training of a neural network model based on a plurality of flow rate change samples carrying medium type labels; The flow rate change rate is input into the second medium type identification model to obtain a second medium type identification result output by the model.

6. The system according to any one of claims 1 to 5, characterized in that The intelligent control module performs negative pressure suction on the medium in the suction catheter during the suction process; the intelligent control module is also configured to execute: determining the total amount of blood aspirated based on flow data collected by a flow sensor for monitoring the flow of the aspiration catheter; When the total amount of blood pumped reaches a first threshold, the negative pressure pumping of the medium in the pumping tube is stopped.

7. The system according to any one of claims 1 to 5, characterized in that The system also includes a manual control module for manually controlling the suction process; the manual control module, the air pressure state conversion module and the intelligent control module are respectively provided with lumens, and the suction catheter is connected to the manual control module, the air pressure state conversion module and the intelligent control module in sequence through the lumens, the manual control module is at the proximal end of the suction inlet, and the intelligent control module is at the distal end of the suction inlet.

8. The system according to claim 1, characterized in that The intelligent control module is provided with an indicator light prompt unit, and the intelligent control module is also configured to execute: After determining the medium type corresponding to the current suction medium of the suction catheter, obtaining the indicator light control mode corresponding to the medium type; the indicator light control mode for each medium type is different; According to the indicator light lighting control method, the indicator light prompt unit is controlled to light up.

9. The system according to claim 1 or 8, characterized in that: The intelligent control module is provided with a sound prompt unit, and the intelligent control module is further configured to execute: determining the total amount of blood aspirated based on flow data collected by a flow sensor for monitoring the flow of the aspiration catheter; When the total amount of blood drawn reaches a second threshold, the sound prompt unit is controlled to play a prompt sound according to a corresponding prompt sound playing mode.

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