Methods of nebulized administration, nebulized administration systems, and computer-readable storage media

By using a dosing compensation algorithm and fitting actual test data in the nebulizer, the single dosing time can be precisely controlled, solving the problem of insufficient dosing accuracy in nebulizers and achieving more precise drug dosage control.

CN119524270BActive Publication Date: 2025-12-12SHENZHEN MEIHAO CHUANGYI MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202411900142.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-12-23
Publication Date
2025-12-12
Estimated Expiration
2044-12-23

AI Technical Summary

Technical Problem

Existing nebulizers have errors in drug delivery accuracy, resulting in insufficient or excessive dosage, which affects the treatment effect, may aggravate the patient's condition, and cause drug waste.

Method used

By obtaining the user-set target dosage, and using a pre-set dosing compensation algorithm and an algorithm generated by fitting actual dosing test data from the nebulizer, the actual single dosing time is determined to precisely control the dosing process of the nebulizer.

Benefits of technology

It improves the drug delivery accuracy of nebulizers, ensuring more accurate drug dosage, reducing drug waste, and lowering the risk of harm to patients.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application relates to the technical field of atomization treatment, in particular to an atomization drug delivery method, an atomization drug delivery system and a computer readable storage medium, which comprise the following steps: obtaining a target drug delivery amount set by a user; determining an actual single drug delivery time according to the target drug delivery amount and a preset drug delivery compensation algorithm; and controlling an atomization device to perform atomization drug delivery according to the actual single drug delivery time, wherein the drug delivery compensation algorithm is obtained by fitting actual drug delivery test data of the atomization device. The technical problem of low atomization precision caused by the differences between components of the atomization device can be reduced.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of atomization treatment, in particular to an atomization administration method, an atomization administration system and a computer readable storage medium. BACKGROUND

[0002] Atomization treatment is one of the important treatment methods for treating respiratory diseases such as bronchial asthma, and the administration accuracy of the atomization device is crucial to the treatment effect. The administration accuracy is usually used to represent the difference between the set target administration amount and the actual administration amount.

[0003] The existing atomization device usually includes components such as air pumps and atomization cups. When atomization administration is performed, the air pump is controlled to generate a pressurized airflow, and the pressurized airflow generates an atomized airflow after flowing through the atomization cup, so that the patient inhales to perform atomization treatment. The administration amount of atomization is mainly controlled by controlling the output time of the pressurized airflow, that is, whether the setting of the atomization administration time is accurate is positively related to the administration accuracy.

[0004] The administration system of the lung function provocation test on the market usually uses the theoretically calculated average atomization rate time as the atomization administration time, that is, the ratio of the set amount and the theoretically calculated average atomization rate of the atomization device calibration is used as the atomization administration time. However, this method has obvious problems: the pressurized airflow is generated by controlling the air pump, and the instantaneous atomization airflow is generated after the pressurized airflow flows through the atomization cup, that is, the instantaneous atomization rate has an error problem with the theoretically calculated average atomization rate of long-time atomization. This error ultimately leads to a large error in administration accuracy. If the administration dose is too small, it cannot achieve good diagnostic effect, and if the administration dose is too large, it may cause secondary injury to the patient, aggravate the patient's condition, and cause waste of drugs.

[0005] Therefore, how to make the actual atomization amount of the atomization device further close to the set atomization amount, that is, to improve the accuracy of atomization of the atomization device, is a technical problem to be solved at present. SUMMARY

[0006] The present application aims to at least solve one of the technical problems existing in the prior art. To this end, the present application provides an atomization administration method, an atomization administration system and a computer readable storage medium, which can reduce the technical problem of low atomization accuracy caused by the difference between the components of the atomization device.

[0007] The atomization administration method according to the first aspect of the present application comprises:

[0008] obtaining a target administration amount set by a user;

[0009] determining an actual single administration time according to the target administration amount and a preset administration compensation algorithm;

[0010] The atomization device is controlled to perform atomization administration according to the actual single administration time, wherein the administration compensation algorithm is fitted according to actual administration test data of the atomization device.

[0011] In some possible implementation manners, the actual single administration time can be determined according to the target administration amount and a preset administration compensation algorithm, and specifically can include:

[0012] A theoretical administration time length is determined according to the target administration amount and a theoretical atomization rate of the atomization device;

[0013] The theoretical administration time length is substituted into an atomization rate correction algorithm to determine a corrected atomization rate, wherein the atomization rate correction algorithm is fitted according to actual atomization rate test data of the atomization device under different single administration time lengths;

[0014] The actual single administration time is determined according to the target administration amount and the corrected atomization rate.

[0015] In some possible implementation manners, the actual single administration time can be determined according to the target administration amount and a preset administration compensation algorithm, and specifically can include:

[0016] The actual single administration time is determined according to the target administration amount and a preset first mapping relationship, and the first mapping relationship is used to represent a mapping relationship between administration time and administration amount.

[0017] In some possible implementation manners, before the step of acquiring the target administration amount set by the user, the atomization administration method can further include:

[0018] A plurality of groups of different single administration time lengths are used to control the atomization device to perform atomization administration;

[0019] Actual atomization rates of the atomization device under different single administration time lengths are determined;

[0020] The atomization rate correction algorithm is fitted according to actual atomization rate and administration time length data that are tested and meet technical requirements of the atomization device.

[0021] In some possible implementation manners, after the step of determining the actual atomization rates of the atomization device under different single administration time lengths, the atomization administration method can further include:

[0022] It is judged whether the actual atomization rate is within a calibrated atomization rate range;

[0023] When the actual atomization rate is within the calibrated atomization rate range, it is determined that the actual atomization rate data meet the technical requirements of the atomization device;

[0024] Otherwise, it is determined that the measured atomization rate data is invalid data.

[0025] In some possible implementation manners, before the step of acquiring the target administration amount set by the user, the atomization administration method further includes:

[0026] The atomization device is controlled to perform atomization administration in multiple groups of different single administration durations.

[0027] Actual administration amounts of the atomization device in different single administration durations are determined.

[0028] The first mapping relationship is generated by fitting according to the actual administration amounts and administration duration data that are obtained through testing and meet the technical requirements of the atomization device.

[0029] In some possible implementation manners, the step of generating the first mapping relationship by fitting according to the actual administration amounts and administration duration data that are obtained through testing and meet the technical requirements of the atomization device specifically includes:

[0030] Actual measured atomization rates of the atomization device in different single administration durations are determined, and the atomization rate correction algorithm is generated by fitting according to the measured atomization rates and administration duration data that are obtained through testing and meet the technical requirements of the atomization device.

[0031] The first mapping relationship is determined according to the atomization rate correction algorithm.

[0032] In some possible implementation manners, the atomization device has an atomization amount measurement component, and the atomization administration method further includes:

[0033] After atomization administration is completed, actual administration of the atomization device is acquired through the atomization rate measurement component and is displayed.

[0034] In a second aspect, an embodiment of the present application provides an atomization administration system, including:

[0035] A host computer, which is configured to execute the atomization administration method in the first aspect and any possible implementation manner based on the first aspect.

[0036] An atomization device, which is configured to perform atomization administration according to an instruction of the host computer.

[0037] In a third aspect, an embodiment of the present application provides a computer readable storage medium, which stores a program. The program is executed by a processor to perform the atomization administration method in the first aspect and any possible implementation manner based on the first aspect.

[0038] The atomization administration method, the atomization administration system, and the computer readable storage medium according to the embodiments of the present application have at least the following beneficial effects:

[0039] After the target dosing amount set by the user is acquired, the actual single dosing time is determined through the target dosing amount and the dosing compensation algorithm, and then the nebulization device is controlled to perform nebulization dosing. Since the dosing compensation algorithm is fitted according to the actual dosing test data of the nebulization device, the dosing compensation algorithm can reflect the difference or characteristics of the nebulization device, and thus the single dosing time actually required by the target dosing amount can be more accurately calculated according to the dosing compensation algorithm, thereby improving the nebulization accuracy of the nebulization device.

[0040] Additional aspects and advantages of the application will be set forth in part in the description which follows, and in part will become apparent to those having ordinary skill in the art upon examination of the following or can be learned from practice of the application. BRIEF DESCRIPTION OF DRAWINGS

[0041] The above and / or additional aspects and advantages of the application will become apparent and be readily understood by considering the following detailed description, including the accompanying drawings, in which:

[0042] Figure 1 An embodiment flowchart of the nebulization dosing method shown by the embodiment of the application;

[0043] Figure 2 Another embodiment flowchart of the nebulization dosing method shown by the embodiment of the application;

[0044] Figure 3 Another embodiment flowchart of the nebulization dosing method shown by the embodiment of the application;

[0045] Figure 4 An embodiment schematic diagram of the nebulization dosing system 400 provided by the embodiment of the application. DETAILED DESCRIPTION

[0046] The embodiments of the application are described in detail below, examples of which are shown in the accompanying drawings, in which the same or similar notations represent the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by reference to the drawings are exemplary only, and are used only for explanation of the application, and cannot be understood as a limitation of the application.

[0047] In the description of the application, the meaning of several is one or more, the meaning of multiple is two or more, greater than, less than, more than, etc. are understood as not including the number, above, below, etc. are understood as including the number. If it is described that the first, the second is only used for the purpose of distinguishing technical features, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features or the sequence of indicated technical features.

[0048] In the description of the present application, it needs to be understood that the orientation description, such as the orientation or position relationship indicated by up, down, left, right, front, back and the like, is based on the orientation or position relationship shown in the drawings, and is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as a limitation on the present application.

[0049] In the description of the present application, the description of the terms "one embodiment", "some embodiments", "exemplary embodiment", "example", "specific example" or "some examples" means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present application. In the present description, the exemplary description of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0050] In the description of the present application, it needs to be explained that, unless otherwise explicitly limited, the words such as setting, installing, connecting and the like should be understood in a broad sense, and the person skilled in the art can reasonably determine the specific meaning of the above words in the present application in combination with the specific content of the technical solution. In addition, the identification of the specific steps in the following does not represent the limitation of the order and execution logic of the steps, and the execution order and execution logic between the steps should be understood and inferred with reference to the content expressed in the embodiments.

[0051] The present application aims to at least solve one of the technical problems existing in the prior art. To this end, the present application proposes an atomization administration method, an atomization administration system and a computer readable storage medium, which can improve the atomization administration precision of the atomization device.

[0052] Some terms related to the present application are further explained below.

[0053] Pulmonary function provocation test: It is mainly used to detect whether there is airway spasm after inhaling bronchial constrictor, and is a diagnostic test for detecting airway hyperresponsiveness and bronchial asthma.

[0054] Atomization: Atomization refers to the conversion of a liquid into fine droplets or particles by a certain method, so that it forms a condition similar to mist.

[0055] Atomization rate: The amount of test element in the solution state sucked and sprayed into the flame is compared with the amount of test element atomized into the flame by the atomizer, which is the standard for testing the quality of the system. It can be said that whether the atomization system meets the standard is also the parameter of the standard atomization rate.

[0056] Further, the following is further illustrated based on the drawings.

[0057] Referring to Figure 1 An optional embodiment of the atomization administration method of the present application is shown, which can include but is not limited to the following steps S101 to S103:

[0058] S101, obtaining a target administration amount set by a user;

[0059] S102, determining an actual single administration time according to the target administration amount and a preset administration compensation algorithm;

[0060] S103, controlling an atomization device to perform atomization administration according to the actual single administration time, wherein the administration compensation algorithm is fitted according to actual administration test data of the atomization device.

[0061] In this embodiment, the atomization administration method can run on a host computer or an atomization administration device body, which can have an operation interface or other interactive components. When running on the host computer, it has a communication connection with the atomization device, which can be a wired or wireless communication connection. Thus, the host computer can issue corresponding administration instructions to the atomization device according to the target administration amount set by the user, so that the atomization device performs atomization administration.

[0062] Specifically, after determining the target administration amount set by the user, the target administration amount can be input into the preset administration compensation algorithm, so as to calculate and determine the actual single administration time. Wherein, the administration compensation algorithm is specifically fitted in advance according to the actual administration test data of the atomization device for multiple times. For example, a plurality of different fixed time groups can be set, such as 0.5s, 1s, 1.5s, 2s, 2.5s, 3s, 3.5s, 4s single administration time experimental groups, and the actual atomization rate and atomization rate of each group are measured, so as to fit and determine the algorithm by using time-atomization rate, or time-atomization liquid amount, etc.

[0063] Then, further, the corresponding administration instructions are generated and issued to the atomization device according to the single administration time, so as to control the atomization device to perform atomization administration. Wherein, the atomization device in this embodiment can include a gas flow output component, a connecting gas path, an atomization control component and an atomization interface, etc. The gas flow output component can include an air compressor and a valve, etc. The pressurized gas flow output by the gas flow output component passes through the atomization cup in the atomization control component from the connecting gas path, generates atomized gas flow, and is transmitted to the atomization interface. The user inhales the atomized gas flow from the atomization interface to realize atomization administration. Therefore, the administration instructions can be specifically issued to the gas flow output component, and the output gas flow time of the gas flow output component is controlled to control the atomization administration process.

[0064] The nebulized drug delivery method according to the embodiments of this application has at least the following beneficial effects:

[0065] After obtaining the user-set target dosage, the actual single-dose administration time is determined using the target dosage and the dosing compensation algorithm, thereby controlling the nebulizer to administer the drug. Since the dosing compensation algorithm is derived from fitting actual dosing test data of the nebulizer, it can reflect the differences or characteristics of the nebulizer. Therefore, based on this algorithm, the actual single-dose administration time required for the target dosage can be calculated more accurately, thereby improving the nebulization accuracy of the nebulizer.

[0066] Among some possible implementations, based on Figure 1 The embodiments shown are described in detail below. Figure 2 , Figure 2 A flowchart illustrating another embodiment of the nebulized drug delivery method of this application is shown. Step S102, determining the actual single-dose delivery time based on the target dosage and a preset drug delivery compensation algorithm, may specifically include:

[0067] S201, Determine the theoretical dosing duration based on the target dosage and the theoretical atomization rate of the nebulizer;

[0068] S202, Substitute the theoretical drug administration time into the nebulization rate correction algorithm to determine the corrected nebulization rate. The nebulization rate correction algorithm is obtained by fitting the measured nebulization rate test data under different single drug administration times of the nebulization device.

[0069] S203, determine the actual single-dose time based on the target dosage and the corrected nebulization rate.

[0070] In this embodiment, the theoretical atomization rate A = Δm / 5min, where Δm is the amount of liquid consumed by atomization within 5 minutes through the atomizing cup, in mg. A can be obtained by taking multiple measurements and calculating the average of the measured atomization rates within 5 minutes, in mg / min.

[0071] Assuming the target dosage is Δm′ in mg, and the number of administrations c is generally a fixed amount in terms of frequency, then the theoretical single administration time t′ = 60 * Δm′ / (A * c) in mg / s.

[0072] Then, t′ is substituted into the nebulization rate correction algorithm to determine the corrected nebulization rate A′. This nebulization rate correction algorithm is obtained by fitting measured nebulization rate test data of the nebulizer under multiple sets of different single-dose durations. The algorithm can be expressed as A′=f(t), where t represents time. In other words, this nebulization rate correction algorithm is used to characterize the mapping relationship between different single-dose durations and nebulization rates.

[0073] Finally, the actual single-dose time t" = Δm' / A' can be obtained according to the target dose Δm' and the corrected atomization rate A'.

[0074] In some possible implementation manners, the actual single-dose time is determined according to the target dose and a preset dose compensation algorithm, and specifically includes:

[0075] The actual single-dose time is determined according to the target dose and a preset first mapping relationship, and the first mapping relationship is used to represent a mapping relationship between a dose and a time.

[0076] In this embodiment, the dose compensation algorithm can also be the first mapping relationship, which can be represented as Δm = F(t), t representing time, i.e., a mapping relationship between a dose and a time. The first mapping relationship can be obtained by fitting test data of the measured atomization dose of the atomization device under multiple groups of different single-dose time lengths.

[0077] In some possible implementation manners, in Figure 2 based on the embodiment shown in Figure 3 , Figure 3 Another embodiment of the atomization and dose method is shown in a flowchart. Before the step of obtaining the target dose set by the user in step S101, the atomization and dose method further includes:

[0078] S301, the atomization device is controlled to atomize and dose by using multiple groups of different single-dose time lengths;

[0079] S302, the measured atomization rate of the atomization device under different single-dose time lengths is determined;

[0080] S303, the atomization rate correction algorithm is generated by fitting the measured atomization rate and dose time length data obtained by testing and meeting the technical requirements of the atomization device.

[0081] In this embodiment, it can be known from the calculation formula of the theoretical single-dose time t' that the only control variable of the atomization device is the single-dose time. The single-dose time range is set according to actual application, for example, the actual single-dose time range can be set as 0.5s-4s, and 0.5s, 1s, 1.5s, 2s, 2.5s, 3s, 3.5s, and 4s single-dose time experimental groups are set respectively. The measured atomization rate of each experimental group can be measured multiple times and averaged, so as to measure the measured atomization rate of each experimental group and record the test data. The measured atomization rate = actual dose / single-dose time length.

[0082] After the test, according to the measured atomization rate and the data of the administration time obtained by the test and meeting the technical requirements of the atomization device, data processing and analysis are performed, the atomization rate regular curve corresponding to different administration times is fitted, and the atomization rate correction algorithm is obtained according to the atomization rate and administration time regular curve fitting, that is, the corrected atomization rate A' = f(t), which can be a linear function or a quadratic function, for example, A' = kt + b, (k, b are related parameters). When fitting, try to express the fitting points by a fitting curve or near the fitting curve, so that the fitting result is more accurate. The atomization rate correction algorithm can be obtained by using the least square method or polynomial regression fitting, and specific details are not described here.

[0083] In some possible implementations, after the step of determining the measured atomization rate of the atomization device under different single administration time lengths in step S302, the atomization administration method can further include:

[0084] determining whether the measured atomization rate is within the calibrated atomization rate range; when it is within the calibrated atomization rate range, it is determined that the measured atomization rate data meets the technical requirements of the atomization device; otherwise, it is determined that the measured atomization rate data is invalid data.

[0085] In this embodiment, after measuring the measured atomization rate data each time, the reliability of the test data also needs to be evaluated. When the measured atomization rate is within the calibrated atomization rate range in the technical specification of the atomization device, it is determined that the measured atomization rate data is valid data and is recorded, otherwise it is determined that it is invalid data, at which time it is necessary to detect whether the air compressor and the atomization cup are damaged and whether the air tightness of the air path is good, and the system cannot be further tested if the problem is not excluded.

[0086] In addition, it needs to be noted that in this embodiment, before the test, that is, before step S301, the theoretical atomization rate A of the atomization device also needs to be tested, and whether the atomization device has a fault is determined according to the measured A. Specifically, according to the aforementioned theoretical atomization rate A = Δm / 5min formula, the single administration time is set to 5min, the measured atomization rate is tested multiple times, preferably 4-5 times, and the theoretical atomization rate A is finally obtained by averaging. It is determined whether the theoretical atomization rate A is within the calibrated atomization rate range in the technical specification of the atomization device. If it is within the range, it is determined that the atomization device is fault-free and can normally execute the subsequent test, otherwise it is determined that the atomization device has a problem, and it is necessary to check whether the air compressor and the atomization cup are damaged and whether the air tightness of the air path is good, and the system cannot be further tested if the problem is not excluded.

[0087] In some possible implementations, before the step of obtaining the target administration amount set by the user, the atomization administration method further includes:

[0088] controlling the atomization administration of the atomization device by using multiple groups of different single administration time lengths.

[0089] determining the actual dosing amount of the aerosolization device under different single dosing durations;

[0090] generating the first mapping relationship according to the actual dosing amount and the dosing duration data obtained through the test and meeting the technical requirements of the aerosolization device.

[0091] In this embodiment, the single dosing time range can be set according to actual application, for example, the actual single dosing time range can be set as 0.5s-4s, and 0.5s, 1s, 1.5s, 2s, 2.5s, 3s, 3.5s and 4s single dosing time experimental groups can be set respectively, and multiple measurements can be taken in each group to obtain the average value, so as to measure the actual dosing amount of each experimental group under the corresponding duration and record the test data.

[0092] After the test, the data processing and analysis are performed according to the actual dosing amount and the dosing duration data obtained through the test and meeting the technical requirements of the aerosolization device, and the first mapping relationship Δm=F(t) is determined by fitting. When fitting, the fitting points are preferably represented by a fitting curve or near the fitting curve, so that the fitting result is more accurate. The specific fitting algorithm can be least square method or polynomial regression fitting, and will not be described in detail here.

[0093] In some possible implementation manners, the step of generating the first mapping relationship according to the actual dosing amount and the dosing duration data obtained through the test and meeting the technical requirements of the aerosolization device specifically includes:

[0094] determining the actual dosing amount of the aerosolization device under different single dosing durations;

[0095] generating the first mapping relationship according to the actual dosing amount and the dosing duration data obtained through the test and meeting the technical requirements of the aerosolization device.

[0096] determining the first mapping relationship according to the aerosolization rate correction algorithm.

[0097] Specifically, since the measured aerosolization rate = actual dosing amount / single dosing duration, and the corrected aerosolization rate A' = f(t), the first mapping relationship Δm=F(t) can be represented as Δm=F(t)=A'xt=f(t)*t. The corrected aerosolization rate A' = f(t) can be obtained by referring to the related embodiment content described above, and is not limited here.

[0098] In some possible implementation manners, the aerosolization device has an aerosolization amount measurement assembly, and the aerosolization dosing method further includes:

[0099] After the aerosolization dosing is completed, the actual dosing condition of the aerosolization device is obtained through the aerosolization rate measurement assembly and is displayed.

[0100] In this embodiment, the atomization device can also be provided with an atomization amount measuring assembly, such as a liquid level detection device provided on the cup wall of the atomization cup. The actual atomization rate and the amount of drug administration can be determined by measuring the change in the liquid level of the atomization cup, and the atomization situation can be displayed to facilitate the user to determine the atomization situation.

[0101] With reference to the drawings Figure 4 , Figure 4 An embodiment of the atomization administration system 400 according to the present application is shown in the figure, wherein the atomization administration system 400 comprises:

[0102] The host computer 401 is configured to execute the atomization administration method according to the above Figure 1 embodiment and any possible implementation manner based on the above Figure 1 embodiment.

[0103] The atomization device 402 is configured to perform atomization administration according to the instruction of the host computer.

[0104] The atomization administration system 400 according to the embodiment of the present application has at least the following beneficial effects:

[0105] After the host computer 401 obtains the target administration amount set by the user, the actual single administration time is determined by the target administration amount and the administration compensation algorithm, and then the atomization device 402 is controlled to perform atomization administration. Since the administration compensation algorithm is fitted according to the actual administration test data of the atomization device, the administration compensation algorithm can reflect the difference or characteristics of the atomization device, so that the actual single administration time required by the target administration amount can be more accurately calculated according to the administration compensation algorithm, thereby improving the atomization precision of the atomization device.

[0106] The present application also provides a computer readable storage medium, which stores a program, and the program is executed by a processor to execute the atomization administration method according to the above Figure 1 embodiment and any possible implementation manner based on the above Figure 1 embodiment.

[0107] The device embodiments described above are only schematic, and the units described as separate components can or can not be physically separate, that is, they can be located in one place, or distributed on multiple network units. Part or all of the modules can be selected according to actual needs to achieve the purpose of the present embodiment.

[0108] Those skilled in the art can understand that all or some of the steps in the method disclosed above can be implemented as software, firmware, hardware, and appropriate combinations thereof. Some or all of the physical components can be implemented as software executed by a processor, such as a central processing unit, a digital signal processor, or a microprocessor, or as hardware, or as an integrated circuit, such as an application-specific integrated circuit. Such software can be distributed on a computer readable medium, which can include computer storage media (or non-transitory media) and communication media (or transitory media). As is well known to those skilled in the art, the term computer storage media includes volatile and non-volatile, removable and non-removable media implemented in any method or technology for storage of information such as computer readable instructions, data structures, program modules or other data. Computer storage media includes, but is not limited to, RAM, ROM, EEPROM, flash memory or other memory technology, CD-ROM, digital versatile disks (DVD) or other optical disk storage, magnetic cassettes, magnetic tapes, storage devices storage or other magnetic storage devices, or any other medium which can be used to store the desired information and which can be accessed by a computer. Furthermore, it is common knowledge to those skilled in the art that communication media typically includes computer readable instructions, data structures, program modules or other data in a modulated data signal such as a carrier wave or other transport mechanism, and can include any information delivery media. It should also be understood that various embodiments provided by the present application can be combined in any manner to achieve different technical effects.

[0109] The above is a specific description of the preferred embodiments of the present application, but the present application is not limited to the above embodiments. Those skilled in the art can make various equivalent modifications or replacements without departing from the spirit of the present application, and these equivalent modifications or replacements are included in the scope defined by the claims of the present application.

Claims

1. A nebulized drug delivery system, characterized in that: The nebulized drug delivery system includes a host computer and a nebulizing device, wherein the host computer is used to perform the following steps: Obtain the target dosage set by the user; The actual single dosing time is determined based on the target dosage and the preset dosing compensation algorithm. The nebulization device is controlled to perform nebulized drug delivery based on the actual single drug delivery time, wherein the drug delivery compensation algorithm is obtained by fitting the actual drug delivery test data of the nebulization device; The step of determining the actual single-dose administration time based on the target dosage and a preset dosing compensation algorithm specifically includes: The theoretical dosing duration is determined based on the target dosage and the theoretical atomization rate of the nebulizer. The theoretical drug administration duration is substituted into the nebulization rate correction algorithm to determine the corrected nebulization rate. The nebulization rate correction algorithm is obtained by fitting measured nebulization rate test data under different single drug administration durations of the nebulization device. The nebulization rate correction algorithm includes: ,in This represents the corrected atomization rate, and t represents time. It can be a linear or quadratic function; The actual single-dose administration time is determined based on the target dosage and the corrected nebulization rate.

2. The nebulized drug delivery system according to claim 1, characterized in that, Before the step of obtaining the user-set target dosage, the host computer is also used to perform the following steps: The nebulizer is used to control the nebulization of the drug by employing multiple sets of different single-dose administration durations. Determine the measured atomization rate of the nebulizer under different single-dose durations; Based on the measured atomization rate and drug delivery duration data obtained from the test and meeting the technical requirements of the atomization device, the atomization rate correction algorithm is generated by fitting.

3. The nebulized drug delivery system according to claim 2, characterized in that, After determining the measured nebulization rate of the nebulizer for different single-dose durations, the host computer is further configured to perform the following steps: Determine whether the measured atomization rate is within the calibrated atomization rate range; When the calibrated atomization rate is within the specified range, the measured atomization rate data is determined to meet the technical requirements of the atomization equipment. Otherwise, the measured atomization rate data is determined to be invalid data.

4. A nebulized drug delivery system, characterized in that: The nebulized drug delivery system includes a host computer and a nebulizing device, wherein the host computer is used to perform the following steps: Obtain the target dosage set by the user; The actual single dosing time is determined based on the target dosage and the preset dosing compensation algorithm. The nebulization device is controlled to perform nebulized drug delivery based on the actual single drug delivery time, wherein the drug delivery compensation algorithm is obtained by fitting the actual drug delivery test data of the nebulization device; The step of determining the actual single-dose administration time based on the target dosage and a preset dosing compensation algorithm specifically includes: The actual single dosing time is determined based on the target dosage and the preset first mapping relationship, wherein the first mapping relationship is used to characterize the mapping relationship between dosing time and dosage; Before the step of obtaining the user-set target dosage, the host computer is also used to perform the following steps: The nebulizer is used to control the nebulization of the drug by employing multiple sets of different single-dose administration durations. Determine the actual drug delivery rate of the nebulizer under different single-dose durations; Based on the actual dosage and duration data obtained from the test and meeting the technical requirements of the nebulization device, the first mapping relationship is fitted and generated. The step of fitting and generating the first mapping relationship based on the actual dosage and duration data obtained from testing and meeting the technical requirements of the nebulization device specifically includes: Determine the measured nebulization rate of the nebulizer under different single-dose durations; based on the measured nebulization rate and dosing duration data obtained from the test and meeting the technical requirements of the nebulizer, a nebulization rate correction algorithm is fitted and generated; The first mapping relationship is determined based on the atomization rate correction algorithm.

5. The nebulized drug delivery system according to claim 4, characterized in that, The atomizing device has an atomization quantity measurement component, and the host computer is also used to perform the following steps: After the nebulized drug delivery is completed, the actual drug delivery status of the nebulization device is obtained through the nebulization rate measurement component and displayed.

Citation Information

Patent Citations

  • Atomizer dosage control method, system and equipment and storage medium

    CN118615523A

  • Devices and methods for respiratory variation monitoring by measurement of respiratory volumes, motion and variability

    US20120041279A1