Bone cement injection anti-leakage planning method and system for spine centrum compression fracture

Abstract

The invention provides a bone cement injection anti-leakage planning method, system and device for spine centrum compression fracture and a computer readable storage medium. The bone cement injection anti-leakage planning method for the spine centrum compression fracture comprises the steps that a spine CT image of a patient is acquired; performing identification and segmentation based on the spine CT image to obtain a fracture centrum CT image of the spine centrum compression fracture part; carrying out three-dimensional reconstruction on the fracture centrum CT image to obtain a fracture centrum three-dimensional model; inputting the three-dimensional model of the fractured vertebral body into a preset bone cement anti-leakage planning model, and outputting a bone cement injection anti-leakage planning scheme; wherein the bone cement injection anti-leakage planning scheme at least comprises the viscosity, the injection amount, the injection position, the injection opportunity and the injection rate of the bone cement. According to the embodiment of the invention, the anti-seepage planning of bone cement injection can be carried out quickly and accurately.

Description

Technical Field

[0001] The present application belongs to the field of bone cement injection leakage prevention, and in particular, relates to a bone cement injection leakage prevention planning method, system, device and computer-readable storage medium for spinal vertebral compression fractures. Background Art

[0002] The common method for spinal compression fractures is to inject bone cement into the diseased vertebra through percutaneous puncture using a specific instrument to increase the strength and stability of the vertebra. If the bone cement is injected well, the patient's compression fracture will occur in a short time, and the height of the vertebra can even be restored. If the injection technique is not good, it will lead to extravasation of bone cement, which may cause pulmonary embolism or other complications.

[0003] At present, in the related technology, the injection amount and injection timing of the bone cement injection module are determined by monitoring through a sensor module, so as to achieve the effect of reducing bone cement leakage.

[0004] However, monitoring through sensor modules is complicated and has low accuracy.

[0005] Therefore, how to quickly and accurately plan the anti-leakage of bone cement injection is a technical problem that needs to be solved urgently by those skilled in the art. Summary of the invention

[0006] The embodiments of the present application provide a method, system, device and computer-readable storage medium for planning the prevention of bone cement injection leakage for spinal vertebral compression fractures, which can quickly and accurately perform bone cement injection prevention of leakage planning.

[0007] In a first aspect, an embodiment of the present application provides a method for planning bone cement injection leakage prevention for spinal vertebral compression fractures, comprising:

[0008] Obtain a CT image of the patient's spine;

[0009] Based on the spinal CT image, identification and segmentation are performed to obtain the fractured vertebral CT image of the spinal vertebral compression fracture site;

[0010] Perform three-dimensional reconstruction on the CT image of the fractured vertebra to obtain a three-dimensional model of the fractured vertebra;

[0011] Input the fractured vertebral body three-dimensional model into a preset bone cement anti-leakage planning model, and output a bone cement injection anti-leakage planning scheme;

[0012] The bone cement injection anti-leakage planning scheme includes at least: bone cement viscosity, injection volume, injection position, injection timing and injection rate.

[0013] Optionally, identification and segmentation are performed based on the spinal CT image to obtain a fractured vertebral CT image of the spinal vertebral compression fracture site, including:

[0014] Inputting the spinal CT image into a preset segmentation network model, and outputting the corresponding fractured vertebral CT image of the spinal vertebral compression fracture site;

[0015] Among them, the entire network structure of the segmentation network model adopts a parallel approach of 4 branches, and each time a new branch is generated, the branches are allowed to fuse information through concatenation;

[0016] Of the four branches output by the final model, only the output of the first branch is used as the final output.

[0017] Optionally, the first branch uses convolutional blocks, each of which consists of 2 convolutional operations, 1 batch normalization, and 1 ReLu activation function;

[0018] The image size remains unchanged throughout the branch, which effectively extracts local detail information of the image;

[0019] In all branches except the first branch, the convolution block is replaced by the Transformer Block to effectively extract the global information in the image.

[0020] Optionally, a three-dimensional reconstruction is performed on the CT image of the fractured vertebra to obtain a three-dimensional model of the fractured vertebra, including:

[0021] Perform volume rendering or surface rendering on the fractured vertebral CT image to obtain an initial fractured vertebral three-dimensional model;

[0022] The initial fractured vertebral 3D model is smoothed and filled with holes to obtain the final fractured vertebral 3D model.

[0023] Optional, bone cement leakage prevention planning model, including:

[0024] Convolutional layer, used to perform convolution operation to obtain feature maps;

[0025] The pooling layer is used to further reduce the feature map size through 3x3 maximum pooling with a stride of 2;

[0026] Dense block, contains 6 units, each unit contains a 1x1 convolution and a 3x3 convolution, the growth rate of each unit is 32, and each dense block gradually increases the number of feature maps by cascading feature maps.

[0027] Optionally, the viscosity, injection volume, and injection position of the bone cement are determined, including:

[0028] Select the appropriate bone cement viscosity based on the type of fracture and the condition of the bone;

[0029] Calculate the amount of bone cement to be injected based on the volume and bone quality of the fracture area in the three-dimensional model;

[0030] By analyzing the three-dimensional model, the precise location of the fracture and the direction of the fracture crack are determined, and the center of the fracture or the largest crack is selected as the injection location for bone cement.

[0031] Optionally, the timing and rate of bone cement injection may include:

[0032] Determine the timing of bone cement injection based on the diffusion of bone cement;

[0033] The injection rate of bone cement is determined based on the diffusion of bone cement, the size of the fracture crack and the hardness of the bone.

[0034] In a second aspect, an embodiment of the present application provides a bone cement injection anti-leakage planning system for spinal vertebral compression fractures, comprising:

[0035] An image acquisition module, used for acquiring a spinal CT image of a patient;

[0036] An image segmentation module is used to identify and segment the spinal CT image to obtain a fractured vertebral CT image of the spinal vertebral compression fracture site;

[0037] A three-dimensional reconstruction module is used to perform three-dimensional reconstruction on the CT image of the fractured vertebra to obtain a three-dimensional model of the fractured vertebra;

[0038] A bone cement anti-leakage planning module is used to input the fractured vertebral body three-dimensional model into a preset bone cement anti-leakage planning model and output a bone cement injection anti-leakage planning scheme;

[0039] The bone cement injection anti-leakage planning scheme includes at least: bone cement viscosity, injection volume, injection position, injection timing and injection rate.

[0040] In a third aspect, an embodiment of the present application provides an electronic device, the electronic device comprising: a processor and a memory storing computer program instructions;

[0041] When the processor executes the computer program instructions, a method for planning the prevention of bone cement injection leakage for spinal vertebral compression fractures is implemented.

[0042] In a fourth aspect, an embodiment of the present application provides a computer-readable storage medium having computer program instructions stored thereon, which, when executed by a processor, implements a method for planning anti-leakage of bone cement injection for spinal vertebral compression fractures.

[0043] The bone cement injection anti-leakage planning method, system, device and computer-readable storage medium for spinal vertebral compression fractures according to the embodiments of the present application can quickly and accurately perform bone cement injection anti-leakage planning.

[0044] The bone cement injection anti-leakage planning method for spinal vertebral compression fractures comprises:

[0045] Obtain a CT image of the patient's spine;

[0046] Based on the spinal CT image, identification and segmentation are performed to obtain the fractured vertebral CT image of the spinal vertebral compression fracture site;

[0047] Perform three-dimensional reconstruction on the CT image of the fractured vertebra to obtain a three-dimensional model of the fractured vertebra;

[0048] Input the fractured vertebral body three-dimensional model into a preset bone cement anti-leakage planning model, and output a bone cement injection anti-leakage planning scheme;

[0049] The bone cement injection anti-leakage planning scheme includes at least: bone cement viscosity, injection volume, injection position, injection timing and injection rate. BRIEF DESCRIPTION OF THE DRAWINGS

[0050] In order to more clearly illustrate the specific implementation methods of the present invention or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0051] Figure 1 It is a flow chart of a method for planning anti-leakage of bone cement injection for spinal vertebral compression fractures provided by one embodiment of the present application;

[0052] Figure 2 It is a structural diagram of a segmentation network model provided by an embodiment of the present application;

[0053] Figure 3 It is a structural schematic diagram of a bone cement anti-leakage planning model provided by an embodiment of the present application;

[0054] Figure 4 It is a structural schematic diagram of a bone cement injection anti-leakage planning system for spinal vertebral compression fractures provided by an embodiment of the present application;

[0055] Figure 5 It is a schematic diagram of the structure of an electronic device provided by an embodiment of the present application. DETAILED DESCRIPTION

[0056] The features and exemplary embodiments of various aspects of the present application will be described in detail below. In order to make the purpose, technical solutions and advantages of the present application clearer, the present application will be further described in detail below in conjunction with the accompanying drawings and specific embodiments. It should be understood that the specific embodiments described herein are only intended to explain the present application, rather than to limit the present application. For those skilled in the art, the present application can be implemented without the need for some of these specific details. The following description of the embodiments is only to provide a better understanding of the present application by illustrating the examples of the present application.

[0057] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the statement "include..." do not exclude the presence of other identical elements in the process, method, article or device including the elements.

[0058] In order to solve the problems of the prior art, the embodiments of the present application provide a method, system, device and computer readable storage medium for planning the anti-leakage of bone cement injection for vertebral compression fractures of the spine. The following first introduces the anti-leakage planning method for bone cement injection for vertebral compression fractures of the spine provided by the embodiments of the present application.

[0059] Figure 1 The flowchart of the method for planning the anti-leakage of bone cement injection for spinal vertebral compression fractures provided by one embodiment of the present application is shown. Figure 1 As shown, the method for preventing leakage of bone cement injection for spinal vertebral compression fractures comprises:

[0060] S101, obtaining a spinal CT image of the patient;

[0061] S102, identifying and segmenting the spinal CT image to obtain a fractured vertebral CT image of the spinal vertebral compression fracture site;

[0062] S103, performing three-dimensional reconstruction on the CT image of the fractured vertebra to obtain a three-dimensional model of the fractured vertebra;

[0063] S104, inputting the fractured vertebral three-dimensional model into a preset bone cement anti-leakage planning model, and outputting a bone cement injection anti-leakage planning scheme; wherein the bone cement injection anti-leakage planning scheme at least includes: bone cement viscosity, injection amount, injection position, injection timing and injection rate.

[0064] Figure 2 : is a schematic diagram of the structure of a segmentation network model provided by an embodiment of the present application; in one embodiment, identification and segmentation are performed based on a spinal CT image to obtain a fractured vertebral CT image of a spinal vertebral compression fracture site, including:

[0065] Inputting the spinal CT image into a preset segmentation network model, and outputting the corresponding fractured vertebral CT image of the spinal vertebral compression fracture site;

[0066] Among them, the entire network structure of the segmentation network model adopts a parallel approach of 4 branches, and each time a new branch is generated, the branches are allowed to fuse information through concatenation;

[0067] Of the four branches output by the final model, only the output of the first branch is used as the final output.

[0068] In one embodiment, the first branch uses convolutional blocks, each of which consists of two convolutional operations, one batch normalization, and one ReLu activation function;

[0069] The image size remains unchanged throughout the branch, which effectively extracts local detail information of the image;

[0070] In all branches except the first branch, the convolution block is replaced by the Transformer Block to effectively extract the global information in the image.

[0071] In one embodiment, three-dimensional reconstruction is performed on the fractured vertebral CT image to obtain a three-dimensional model of the fractured vertebra, including:

[0072] Perform volume rendering or surface rendering on the fractured vertebral CT image to obtain an initial fractured vertebral three-dimensional model;

[0073] The initial fractured vertebral 3D model is smoothed and filled with holes to obtain the final fractured vertebral 3D model.

[0074] Figure 3: is a schematic diagram of the structure of a bone cement anti-leakage planning model provided by an embodiment of the present application; in one embodiment, the bone cement anti-leakage planning model includes:

[0075] Convolutional layer, used to perform convolution operation to obtain feature maps;

[0076] The pooling layer is used to further reduce the feature map size through 3x3 maximum pooling with a stride of 2;

[0077] Dense block, contains 6 units, each unit contains a 1x1 convolution and a 3x3 convolution, the growth rate of each unit is 32, and each dense block gradually increases the number of feature maps by cascading feature maps.

[0078] In one embodiment, the determination of the viscosity, injection volume, and injection position of the bone cement includes:

[0079] Select the appropriate bone cement viscosity based on the type of fracture and the condition of the bone;

[0080] Calculate the amount of bone cement to be injected based on the volume and bone quality of the fracture area in the three-dimensional model;

[0081] By analyzing the three-dimensional model, the precise location of the fracture and the direction of the fracture crack are determined, and the center of the fracture or the largest crack is selected as the injection location for bone cement.

[0082] In one embodiment, the determination of the injection timing and injection rate of bone cement includes:

[0083] Determine the timing of bone cement injection based on the diffusion of bone cement;

[0084] The injection rate of bone cement is determined based on the diffusion of bone cement, the size of the fracture crack and the hardness of the bone.

[0085] Figure 4 1 is a schematic diagram of a bone cement injection anti-leakage planning system for spinal vertebral compression fractures provided by an embodiment of the present application; the bone cement injection anti-leakage planning system for spinal vertebral compression fractures comprises:

[0086] An image acquisition module 401 is used to acquire a spinal CT image of a patient;

[0087] An image segmentation module 402 is used to identify and segment the spinal CT image to obtain a fractured vertebral CT image of the spinal vertebral compression fracture site;

[0088] A three-dimensional reconstruction module 403 is used to perform three-dimensional reconstruction on the fractured vertebral CT image to obtain a three-dimensional model of the fractured vertebra;

[0089] The bone cement anti-leakage planning module 404 is used to input the fractured vertebral body three-dimensional model into a preset bone cement anti-leakage planning model and output a bone cement injection anti-leakage planning scheme;

[0090] The bone cement injection anti-leakage planning scheme includes at least: bone cement viscosity, injection volume, injection position, injection timing and injection rate.

[0091] Figure 5 A schematic diagram of the structure of an electronic device provided in an embodiment of the present application is shown.

[0092] The electronic device may include a processor 501 and a memory 502 storing computer program instructions.

[0093] Specifically, the processor 501 may include a central processing unit (CPU), or an application specific integrated circuit (ASIC), or may be configured to implement one or more integrated circuits of the embodiments of the present application.

[0094] The memory 502 may include a large capacity memory for data or instructions. By way of example and not limitation, the memory 502 may include a hard disk drive (HDD), a floppy disk drive, a flash memory, an optical disk, a magneto-optical disk, a magnetic tape, or a universal serial bus (USB) drive or a combination of two or more of these. Where appropriate, the memory 502 may include a removable or non-removable (or fixed) medium. Where appropriate, the memory 502 may be inside or outside the electronic device. In a particular embodiment, the memory 502 may be a non-volatile solid-state memory.

[0095] In one embodiment, the memory 502 may be a read-only memory (ROM). In one embodiment, the ROM may be a mask-programmed ROM, a programmable ROM (PROM), an erasable PROM (EPROM), an electrically erasable PROM (EEPROM), an electrically rewritable ROM (EAROM), or a flash memory, or a combination of two or more of these.

[0096] The processor 501 reads and executes the computer program instructions stored in the memory 502 to implement any one of the bone cement injection anti-leakage planning methods for spinal vertebral compression fractures in the above embodiments.

[0097] In one example, the electronic device may further include a communication interface 503 and a bus 510. Figure 5As shown, the processor 501, the memory 502, and the communication interface 503 are connected via a bus 510 and communicate with each other.

[0098] The communication interface 503 is mainly used to implement communication between various modules, systems, units and / or devices in the embodiments of the present application.

[0099] Bus 510 includes hardware, software or both, and the parts of electronic equipment are coupled to each other. For example, but not limitation, bus may include accelerated graphics port (AGP) or other graphics bus, enhanced industrial standard architecture (EISA) bus, front side bus (FSB), hypertransport (HT) interconnection, industrial standard architecture (ISA) bus, infinite bandwidth interconnection, low pin count (LPC) bus, memory bus, micro channel architecture (MCA) bus, peripheral component interconnection (PCI) bus, PCI-Express (PCI-X) bus, serial advanced technology attachment (SATA) bus, video electronics standard association local (VLB) bus or other suitable bus or two or more of these combinations. In appropriate cases, bus 510 may include one or more buses. Although the present application embodiment describes and shows a specific bus, the application considers any suitable bus or interconnection.

[0100] In addition, in combination with the bone cement injection anti-leakage planning method for spinal vertebral compression fractures in the above embodiments, the present application embodiment can provide a computer-readable storage medium for implementation. The computer-readable storage medium stores computer program instructions; when the computer program instructions are executed by the processor, any one of the bone cement injection anti-leakage planning methods for spinal vertebral compression fractures in the above embodiments is implemented.

[0101] It should be clear that the present application is not limited to the specific configuration and processing described above and shown in the figures. For the sake of simplicity, a detailed description of the known method is omitted here. In the above embodiments, several specific steps are described and shown as examples. However, the method process of the present application is not limited to the specific steps described and shown, and those skilled in the art can make various changes, modifications and additions, or change the order between the steps after understanding the spirit of the present application.

[0102] The functional modules shown in the above-described block diagram can be implemented as hardware, software, firmware or a combination thereof. When implemented in hardware, it can be, for example, an electronic circuit, an application specific integrated circuit (ASIC), appropriate firmware, a plug-in, a function card, etc. When implemented in software, the elements of the present application are programs or code segments that are used to perform the required tasks. Programs or code segments can be stored in machine-readable media, or transmitted on a transmission medium or a communication link by a data signal carried in a carrier wave. "Machine-readable media" can include any medium capable of storing or transmitting information. Examples of machine-readable media include electronic circuits, semiconductor memory devices, ROM, flash memory, erasable ROM (EROM), floppy disks, CD-ROMs, optical disks, hard disks, optical fiber media, radio frequency (RF) links, etc. Code segments can be downloaded via computer networks such as the Internet, intranets, etc.

[0103] It should also be noted that the exemplary embodiments mentioned in this application describe some methods or systems based on a series of steps or systems. However, this application is not limited to the order of the above steps, that is, the steps can be performed in the order mentioned in the embodiment, or in a different order from the embodiment, or several steps can be performed simultaneously.

[0104] The above reference is according to the method of the embodiment of the present application, the flowchart and / or block diagram of the system and computer program product described various aspects of the present application.It should be understood that each square block in the flowchart and / or block diagram and the combination of each square block in the flowchart and / or block diagram can be realized by computer program instructions.These computer program instructions can be provided to the processor of a general-purpose computer, a special-purpose computer or other programmable data processing system, to produce a kind of machine, so that these instructions executed by the processor of the computer or other programmable data processing system enable the realization of the function / action specified in one or more square blocks of the flowchart and / or block diagram.Such a processor can be but is not limited to a general-purpose processor, a special-purpose processor, a special application processor or a field programmable logic circuit.It can also be understood that each square block in the block diagram and / or the flowchart and the combination of the square blocks in the block diagram and / or the flowchart can also be realized by the dedicated hardware that performs the specified function or action, or can be realized by the combination of dedicated hardware and computer instructions.

[0105] The above is only a specific implementation of the present application. Those skilled in the art can clearly understand that for the convenience and simplicity of description, the specific working processes of the systems, modules and units described above can refer to the corresponding processes in the aforementioned method embodiments, and will not be repeated here. It should be understood that the protection scope of the present application is not limited to this. Any technician familiar with the technical field can easily think of various equivalent modifications or replacements within the technical scope disclosed in this application, and these modifications or replacements should be included in the protection scope of this application.

Claims

1. A method for planning anti-leakage of bone cement injection for spinal vertebral compression fractures, characterized in that: include: Obtain a CT image of the patient's spine; Based on the spinal CT image, identification and segmentation are performed to obtain the fractured vertebral CT image of the spinal vertebral compression fracture site; Perform three-dimensional reconstruction on the CT image of the fractured vertebra to obtain a three-dimensional model of the fractured vertebra; Input the fractured vertebral body three-dimensional model into a preset bone cement anti-leakage planning model, and output a bone cement injection anti-leakage planning scheme; The bone cement injection anti-leakage planning scheme includes at least: bone cement viscosity, injection volume, injection position, injection timing and injection rate.

2. The method for planning anti-leakage of bone cement injection for spinal vertebral compression fractures according to claim 1, characterized in that: Based on the spinal CT image, identification and segmentation are performed to obtain the fractured vertebral CT image of the spinal vertebral compression fracture site, including: Inputting the spinal CT image into a preset segmentation network model, and outputting the corresponding fractured vertebral CT image of the spinal vertebral compression fracture site; Among them, the entire network structure of the segmentation network model adopts a parallel approach of 4 branches, and each time a new branch is generated, the branches are allowed to fuse information through concatenation; Of the four branches output by the final model, only the output of the first branch is used as the final output.

3. The method for planning anti-leakage of bone cement injection for spinal vertebral compression fractures according to claim 2, characterized in that: The first branch uses convolution blocks, each of which consists of 2 convolutional operations, 1 batchnormalization, and 1 ReLu activation function; The image size remains unchanged throughout the branch, which effectively extracts local detail information of the image; In all branches except the first branch, the convolution block is replaced by the Transformer Block to effectively extract the global information in the image.

4. The method for planning anti-leakage of bone cement injection for spinal vertebral compression fractures according to claim 1, characterized in that: The fractured vertebrae CT images are reconstructed in three dimensions to obtain a fractured vertebrae three-dimensional model, including: Perform volume rendering or surface rendering on the fractured vertebral CT image to obtain an initial fractured vertebral three-dimensional model; The initial fractured vertebral 3D model is smoothed and filled with holes to obtain the final fractured vertebral 3D model.

5. The method for planning anti-leakage of bone cement injection for spinal vertebral compression fractures according to claim 1, characterized in that: Bone cement anti-leakage planning model, including: Convolutional layer, used to perform convolution operation to obtain feature maps; The pooling layer is used to further reduce the feature map size through 3x3 maximum pooling with a stride of 2; Dense block, contains 6 units, each unit contains a 1x1 convolution and a 3x3 convolution, the growth rate of each unit is 32, and each dense block gradually increases the number of feature maps by cascading feature maps.

6. The method for planning anti-leakage of bone cement injection for spinal vertebral compression fractures according to claim 1, characterized in that: The viscosity, injection volume, and injection location of bone cement are determined, including: Select the appropriate bone cement viscosity based on the type of fracture and the condition of the bone; Calculate the amount of bone cement to be injected based on the volume and bone quality of the fracture area in the three-dimensional model; By analyzing the three-dimensional model, the precise location of the fracture and the direction of the fracture crack are determined, and the center of the fracture or the largest crack is selected as the injection location for bone cement.

7. The method for planning anti-leakage of bone cement injection for spinal vertebral compression fractures according to claim 6, characterized in that: The timing and rate of bone cement injection include: Determine the timing of bone cement injection based on the diffusion of bone cement; The injection rate of bone cement is determined based on the diffusion of bone cement, the size of the fracture crack and the hardness of the bone.

8. A bone cement injection anti-leakage planning system for spinal vertebral compression fractures, characterized in that: The system comprises: An image acquisition module, used for acquiring a spinal CT image of a patient; An image segmentation module is used to identify and segment the spinal CT image to obtain a fractured vertebral CT image of the spinal vertebral compression fracture site; A three-dimensional reconstruction module is used to perform three-dimensional reconstruction on the CT image of the fractured vertebra to obtain a three-dimensional model of the fractured vertebra; A bone cement anti-leakage planning module is used to input the fractured vertebral body three-dimensional model into a preset bone cement anti-leakage planning model and output a bone cement injection anti-leakage planning scheme; The bone cement injection anti-leakage planning scheme includes at least: bone cement viscosity, injection volume, injection position, injection timing and injection rate.

9. An electronic device, characterized in that: The electronic device comprises: a processor and a memory storing computer program instructions; When the processor executes the computer program instructions, the method for planning the prevention of bone cement injection leakage for spinal vertebral compression fractures as described in any one of claims 1-7 is implemented.

10. A computer-readable storage medium, characterized in that: The computer-readable storage medium stores computer program instructions, which, when executed by a processor, implement the bone cement injection anti-leakage planning method for spinal vertebral compression fractures as described in any one of claims 1-7.

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