A plant source sleep-aiding composition, and a preparation method and application thereof

Abstract

The application discloses a plant source sleep-aiding composition and a preparation method and application thereof, relates to the technical field of sleep-aiding products, and comprises the following steps: S1, uniformly mixing, frying and obtaining a first material by taking, according to weight fractions, a combination of spina date seed, poria cocos, wheat, dried ginger and oyster shell; S2, mixing and grinding the first material with hot water to obtain a first slurry; S3, adding deacetylated chitin into the first slurry, and stirring by introducing nitrogen to obtain a second slurry; S4, performing centrifugal treatment on the second slurry, and performing vacuum evaporation concentration on supernatant collected to one third of the original volume to obtain a concentrated solution; and S5, mixing the concentrated solution and aloe extract to obtain the plant source sleep-aiding composition. Through reasonable collocation and processing of medicinal materials, the application can fully release effective components in the medicinal materials, effectively improve the bioavailability of the medicinal materials, and significantly improve the effect of improving sleep quality.

Description

Technical Field

[0001] This invention relates to the field of sleep aid products, specifically to a plant-derived sleep aid composition, its preparation method, and its application. Background Technology

[0002] In today's fast-paced society, individuals face ever-increasing mental stress, leading to increasingly poor sleep quality and severely impacting daytime mental well-being. Consequently, many people resort to traditional Chinese medicine formulas such as Suanzaoren Tang, Guipi Tang, and Wendan Tang to regulate their bodies and improve sleep quality. However, these formulas are primarily consumed as decoctions, leaving many active ingredients in the dregs that remain undissolved. This not only reduces the bioavailability of the herbs but also diminishes the decoction's effectiveness in improving sleep quality. Summary of the Invention

[0003] The purpose of this invention is to overcome the shortcomings of the prior art. This invention provides a plant-derived sleep aid composition, its preparation method and application. By rationally combining and processing medicinal materials, the effective components in the medicinal materials can be fully released, which can not only effectively improve the bioavailability of the medicinal materials, but also significantly improve their effect on improving sleep quality.

[0004] This invention provides a method for preparing a plant-derived sleep-aiding composition, comprising the following steps:

[0005] S1. By weight, take 10-20 parts of jujube seed, 6-9 parts of poria cocos, 6-9 parts of wheat, 3-5 parts of dried ginger and 3-5 parts of oyster shell, mix them evenly, and stir-fry at 60-80℃ for 30-50 minutes to obtain the first material.

[0006] S2. Mix and grind the first material with 2 to 3 times its volume of hot water to obtain the first slurry;

[0007] S3. Add 0.1-0.3 wt% of deacetylated chitosan to the first slurry and stir with nitrogen for at least 1 hour to obtain the second slurry;

[0008] S4. The second slurry is centrifuged, and the collected supernatant is concentrated by vacuum evaporation to one-third of its original volume to obtain a concentrated liquid.

[0009] S5. The concentrated liquid and aloe vera extract are mixed at a volume ratio of 1:5 to 5:1 to obtain a plant-based sleep aid composition.

[0010] Specifically, before step S1, the following steps are also included:

[0011] Moisten Poria cocos with glutinous rice wine, stir-fry until dry at 80-90℃, and let cool before use; and / or

[0012] Soak dried ginger in glutinous rice vinegar, stir-fry until dry at 110-120℃, and let cool before use.

[0013] Specifically, in step S1, before the stir-frying process, the jujube seed, the poria cocos, the wheat, the dried ginger, and the oyster shell are crushed.

[0014] Specifically, in step S2, the temperature of the hot water is greater than 90°C.

[0015] Specifically, in step S3, the flow rate of the nitrogen gas is in the range of 50 to 60 cubic decimeters per hour.

[0016] Specifically, in step S4, the rotation speed range of the centrifugation process is 10,000 to 15,000 rpm.

[0017] Specifically, in step S5, the aloe extract is a Curacao aloe extract with a purity of 92-99%.

[0018] Specifically, step S5 also includes:

[0019] Cherry extract and banana extract are added to the mixture of the concentrate and the aloe vera extract, wherein the amount of cherry extract added is 5-15 wt% of the mass of the concentrate, and the amount of banana extract added is 10-20 wt% of the mass of the concentrate.

[0020] The present invention also provides a plant-derived sleep aid composition, which is prepared by the method described above.

[0021] The present invention also provides the application of the aforementioned plant-derived sleep-aiding composition in the preparation of cosmetics or health products for sleep aiding. When applied to the preparation of cosmetics for sleep aiding, the concentrated liquid and the aloe vera extract are mixed in a volume ratio of 5:1 to 5 in the plant-derived sleep-aiding composition; when applied to the preparation of health products for sleep aiding, the concentrated liquid and the aloe vera extract are mixed in a volume ratio of 1:1 to 5 in the plant-derived sleep-aiding composition.

[0022] Compared with the prior art, the beneficial effects of the present invention are:

[0023] In the preparation method of the plant-derived sleep aid composition of the present invention, the combination of medicinal materials is reasonable. The combination of 10-20 parts of jujube seed, 6-9 parts of poria cocos, 6-9 parts of wheat and 3-5 parts of oyster shell can effectively enhance the calming effect, thereby achieving the effect of sedation and sleep aid, and the effect of sleep aid is excellent. Dried ginger is spicy, and the spiciness of 3-5 parts of dried ginger is more suitable. It can not only promote blood circulation and accelerate the absorption of the plant-derived sleep aid composition by the human body, but also give people a warm sensory feeling, which can effectively promote people to fall asleep.

[0024] By mixing jujube seed, poria cocos, wheat, oyster shell, and dried ginger evenly, and then roasting, grinding with hot water to form a paste, adding deacetylated chitin and stirring with nitrogen, centrifuging to collect the supernatant for concentration, and mixing with aloe vera extract, the effective components in the medicinal materials are fully released. This process can produce a composition with good sleep-aiding effects, which can not only effectively improve the bioavailability of the medicinal materials, but also significantly improve their sleep quality. Attached Figure Description

[0025] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0026] Figure 1 This is a schematic flowchart illustrating the preparation method of the plant-derived sleep-aiding composition in this embodiment of the invention. Detailed Implementation

[0027] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0028] This invention provides a method for preparing a plant-derived sleep-aiding composition. Figure 1 A schematic flowchart illustrating a method for preparing a plant-derived sleep-aiding composition according to an embodiment of the present invention is shown, including the following steps:

[0029] S1. By weight, take 10-20 parts of jujube seed, 6-9 parts of poria cocos, 6-9 parts of wheat, 3-5 parts of dried ginger and 3-5 parts of oyster shell, mix them evenly, and stir-fry at 60-80℃ for 30-50 minutes to obtain the first material.

[0030] Specifically, jujube seed can nourish the heart and liver, improve symptoms such as insomnia, excessive dreaming, and palpitations, and also has a good relieving effect on restlessness; Poria cocos has the effect of nourishing the heart and calming the mind, which helps improve sleep quality and reduce negative emotions such as irritability and anxiety; wheat is sweet and neutral in nature, and has the effect of nourishing the heart and calming the mind, and is suitable for symptoms such as restlessness and insomnia; oyster shell enters the heart meridian, and has the effect of calming the mind and can be used to treat symptoms such as palpitations, insomnia, and restlessness; dried ginger is pungent and hot in nature, and can warm the middle and dispel cold, restore yang and unblock the meridians.

[0031] A combination of 10-20 parts jujube seed, 6-9 parts poria cocos, 6-9 parts wheat, and 3-5 parts oyster shell can effectively enhance the calming effect, thereby achieving a sedative and sleep-inducing effect, and providing excellent sleep aid. Dried ginger is spicy, and 3-5 parts of dried ginger have a suitable spiciness, which can not only promote blood circulation and accelerate the body's absorption of the plant-based sleep aid composition, but also give people a warm sensory experience, which can effectively promote people to fall asleep.

[0032] Furthermore, stir-frying at 60-80℃ for 30-50 minutes can make the active ingredients in the medicinal materials more easily dissolve, which is beneficial to improving the bioavailability of the drugs; it can also reduce some irritating components in the medicinal materials, thereby further improving the aroma of the medicinal materials and adding a pleasant medicinal fragrance to the plant-based sleep aid composition; in addition, this can also sterilize and disinfect, ensuring the quality stability of the slurry obtained by subsequent grinding.

[0033] In some specific embodiments, before step S1, the process further includes: moistening Poria cocos with glutinous rice wine, stir-frying and drying it at 80-90°C, and then cooling it for later use. After being processed with glutinous rice wine, the medicinal efficacy of Poria cocos is enhanced, allowing it to better exert its effects on nourishing the heart and calming the mind. Simultaneously, the processing with glutinous rice wine allows Poria cocos to absorb the sweet aroma of the wine, which helps to add a pleasant sweet fragrance to the resulting plant-based sleep-aiding composition. Preferably, moistening Poria cocos with glutinous rice wine and stir-frying and drying it at 80-83°C provides a gentle temperature, preventing it from burning.

[0034] Specifically, the mass ratio of glutinous rice wine to Poria cocos is in the range of 1:5 to 10, and the alcohol concentration of the glutinous rice wine is in the range of 15% vol to 20% vol, which has a good effect on the processing of Poria cocos. Preferably, the mass ratio of glutinous rice wine to Poria cocos is 1:7, and the alcohol concentration of the glutinous rice wine is 18% vol. The processed Poria cocos has a yellowish-brown surface and a distinct aroma of caramel and sweetness from the wine.

[0035] In some specific embodiments, before step S1, the method further includes: soaking dried ginger in glutinous rice vinegar, stir-frying it at 110-120°C until dry, and then cooling it for later use. After being processed with glutinous rice vinegar, the solubility of the active ingredients in the dried ginger not only increases, but also reduces its irritation, making the spicy flavor milder and less likely to cause a burning sensation while still providing a warming effect. Preferably, soaking the dried ginger in glutinous rice vinegar and stir-frying it at 115-120°C is a high-temperature process that facilitates rapid evaporation of moisture.

[0036] Specifically, the mass ratio of glutinous rice vinegar to dried ginger is in the range of 1:8 to 12, and the acetic acid content of the glutinous rice vinegar is in the range of 3wt% to 8wt%, which has a good effect on the processing of dried ginger. Preferably, the mass ratio of glutinous rice vinegar to dried ginger is 1:10, and the acetic acid content of the glutinous rice vinegar is 6wt%. The processed dried ginger has a brownish-brown surface, a crisp texture, and a special aroma.

[0037] In some specific embodiments, in step S1, before the stir-frying process, the jujube seed, the poria cocos, the wheat, the dried ginger, and the oyster shell are crushed, which helps to improve the processing effect and facilitates subsequent grinding and pulping.

[0038] S2. Mix and grind the first material with 2 to 3 times its volume of hot water to obtain the first slurry;

[0039] During the mixing and grinding process, the calcium carbonate in the oyster shells can adjust the pH value of the slurry, preventing it from becoming acidic and thus improving the quality of the first slurry obtained.

[0040] The volume of hot water is 2 to 3 times that of the first material, which can fully dissolve the effective components of the medicinal materials during the grinding process; at the same time, the amount of water is not too much, which facilitates the subsequent concentration operation.

[0041] In some specific embodiments, the temperature of the hot water is greater than 90°C, which can soften the first material and facilitate grinding and pulping the first material; moreover, 90°C is higher than the discharge temperature of the first material, so it will not weaken the medicinal properties of the first material, and at the same time it can inhibit the reproduction of microorganisms and ensure the quality of the first slurry.

[0042] In some specific embodiments, after obtaining the first slurry, it is ultrasonically treated while still hot for 3-5 minutes. Utilizing the strong cavitation effect, mechanical vibration, disturbance effect, diffusion, and stirring action generated by ultrasound, the effective components in the first slurry are further dissolved, significantly optimizing its properties while ensuring uniform distribution of components and eliminating potential agglomeration or precipitation. Specifically, the ultrasonic frequency range of the ultrasonic treatment is 20-30 kHz, exhibiting a very strong cavitation effect.

[0043] S3. Add 0.1-0.3 wt% of deacetylated chitosan to the first slurry and stir with nitrogen for at least 1 hour to obtain the second slurry;

[0044] Deacetylated chitosan has good antibacterial properties, which can effectively extend the shelf life of plant-based sleep aid compositions. Stirring with nitrogen promotes the dissolution of deacetylated chitosan, cools the slurry, and removes oxygen from the slurry, reducing contact between the slurry and oxygen, which also helps extend the shelf life of the plant-based sleep aid compositions.

[0045] Preferably, 0.2 wt% of deacetylated chitin is added to the first slurry and stirred with nitrogen for 1.7 h to obtain the second slurry. This operation not only ensures the full dissolution and dispersion of deacetylated chitin in the slurry, but also further promotes the cooling and deoxygenation effect of the slurry through long-term nitrogen stirring, thereby maximizing the shelf life of the plant-derived sleep aid composition and ensuring the stability and safety of the product.

[0046] In some specific embodiments, the nitrogen flow rate is in the range of 50-60 cubic decimeters per hour, which can generate a large number of bubbles that are evenly distributed and rise rapidly in the slurry. This not only achieves good stirring but also effectively reduces the oxygen content of the slurry. Specifically, the nitrogen flow rate is 55 cubic decimeters per hour, which will not cause slurry splashing.

[0047] S4. The second slurry is centrifuged, and the collected supernatant is concentrated by vacuum evaporation to one-third of its original volume to obtain a concentrated liquid.

[0048] Specifically, the centrifugation speed range is 10,000 to 15,000 rpm. If the speed is less than 10,000 rpm, the residue cannot be completely precipitated, resulting in the supernatant still containing a lot of impurities, which will reduce the quality of the supernatant. If the speed is greater than 15,000 rpm, some active ingredients may precipitate along with the residue due to excessive centrifugal force, which will also reduce the quality of the supernatant.

[0049] Specifically, the collected supernatant is poured into an evaporator, and the evaporator is evacuated to maintain a vacuum level of 200–400 Pa. This helps to lower the temperature at which water evaporates, improve evaporation efficiency, and reduce the loss of active ingredients. Furthermore, the supernatant is evaporated and concentrated at 70–80°C. This temperature range ensures evaporation efficiency while minimizing the loss of active ingredients.

[0050] Concentrating the supernatant to one-third of its original volume not only increases the concentration of the active ingredients in the supernatant but also provides a high-quality concentrate for subsequent processing or application.

[0051] S5. The concentrated liquid and aloe vera extract are mixed at a volume ratio of 1:5 to 5:1 to obtain a plant-based sleep aid composition.

[0052] Aloe vera extract can be consumed or applied topically, and its inherent viscosity makes it an ideal matrix material, effectively dispersing and carrying the active ingredients in the concentrate. By mixing the concentrate with aloe vera extract, not only can the uniform distribution of the active ingredients in the composition be ensured, but the viscosity of the aloe vera extract can also be used to adjust the overall texture of the composition, making it more suitable for different application scenarios and user needs.

[0053] Aloe vera extract is rich in various nutrients beneficial to the human body, such as polysaccharides, amino acids, and vitamins. These components can further enhance the effects of plant-based sleep aid compositions. When the composition is applied topically, these nutrients in aloe vera extract can nourish the skin and improve its condition, thus providing users with a more comprehensive and comfortable experience. When the composition is taken internally, these nutrients in aloe vera extract can cool and relieve internal heat, strengthen the stomach and intestines, and help improve the body's immunity.

[0054] In some specific embodiments, the aloe extract is a 92-99% pure Aloe barbadensis extract; compared with other aloe extracts, Aloe barbadensis extract is mild and non-irritating, and has good safety.

[0055] In some specific embodiments, step S5 further includes adding cherry extract and banana extract to the mixture of the concentrate and the aloe vera extract. The amount of cherry extract added is 5-15 wt% of the mass of the concentrate, and the amount of banana extract added is 10-20 wt% of the mass of the concentrate. Cherry extract is rich in tryptophan and serotonin, as well as a significant amount of melatonin, which can effectively improve sleep. Banana extract is also rich in tryptophan, which can improve sleep as well. Furthermore, both cherry extract and banana extract are rich in vitamins and trace elements, which are beneficial to human health.

[0056] When the composition is used externally, such as in the form of a face cream or serum, the amount of cherry extract added is 10-15 wt% of the concentrate, and the amount of banana extract added is 15-20 wt% of the concentrate. This amount ensures that the active ingredients in the extracts can fully penetrate the skin and play a role in aiding sleep.

[0057] When the composition is taken orally, such as in the form of oral liquid or capsules, the amount of cherry extract added is 5-10 wt% of the mass of the concentrate, and the amount of banana extract added is 10-15 wt% of the mass of the concentrate. The absorption effect is good when taken orally, so the amount added can be reduced.

[0058] The preparation method of the plant-derived sleep aid composition of the present invention involves uniformly mixing jujube seed, poria cocos, wheat, oyster shell, and dried ginger. The combination of medicinal materials is reasonable. The process includes stir-frying, grinding with hot water to form a slurry, adding deacetylated chitin and stirring under nitrogen, centrifuging to collect the supernatant and concentrating, and mixing with aloe vera extract. This process ensures the full release of the effective components in the medicinal materials, resulting in a composition with good sleep aid effects. It not only effectively improves the bioavailability of the medicinal materials but also significantly enhances their effect on improving sleep quality. Moreover, the prepared plant-derived sleep aid composition has good safety and a long shelf life. It can be taken internally or applied externally, making it suitable for different application scenarios and user needs.

[0059] This invention also provides a plant-based sleep aid composition, which is prepared by the same method used for preparing plant-based sleep aid compositions. The composition can be subjected to irradiation sterilization treatment to extend its shelf life. Specifically, the irradiation sterilization radiation dose is 1–5 kGy, which can effectively eliminate microorganisms in the plant-based sleep aid composition.

[0060] The present invention also provides an application of the aforementioned plant-derived sleep-aiding composition in the preparation of cosmetics or health products that aid sleep. It is convenient to use, and the plant-derived sleep-aiding composition can be directly added to cosmetics or health products, or the plant-derived sleep-aiding composition can be freeze-dried into powder and then added to cosmetics or health products.

[0061] Specifically, when applied to the preparation of cosmetics for aiding sleep, in the plant-based sleep-aiding composition, the concentrate and the aloe vera extract are mixed at a volume ratio of 5:1 to 5 to ensure that the effective ingredients of the concentrate can fully penetrate the skin and exert their sleep-aiding effect. When applied to the preparation of health products for aiding sleep, in the plant-based sleep-aiding composition, the concentrate and the aloe vera extract are mixed at a volume ratio of 1:1 to 5. This method improves the absorption of the concentrate when taken orally, thus reducing the amount of concentrate required.

[0062] Example 1

[0063] (1) By weight, take 15 parts of jujube seed, 8 parts of poria cocos, 7 parts of wheat, 4 parts of dried ginger and 4 parts of oyster shell, mix them evenly, and stir-fry at 70℃ for 40 minutes to obtain the first material.

[0064] (2) The first material is mixed and ground with 2.5 times its volume of hot water to obtain the first slurry;

[0065] (3) Add 0.2 wt% of deacetylated chitin to the first slurry and stir with nitrogen for 1 h to obtain the second slurry;

[0066] (4) Centrifuge the second slurry and concentrate the collected supernatant by vacuum evaporation to one-third of its original volume to obtain a concentrated liquid;

[0067] (5) Mix the concentrate and aloe vera extract at a volume ratio of 1:3 to obtain a plant-derived sleep aid composition.

[0068] Animal experiments:

[0069] Researchers evaluated the effects of the plant-derived sleep aid composition of Example 1 on mouse sleep using a subthreshold dose sodium pentobarbital sleep experiment, a prolonged sodium pentobarbital sleep time experiment, and a sodium barbital sleep latency experiment.

[0070] One hundred and fifty SPF-grade healthy adult male mice (weighing 20 ± 2 g) were randomly divided into three groups: A, B, and C, with 50 mice in each group. Group A underwent a subthreshold dose pentobarbital sodium sleep experiment, group B underwent a pentobarbital sodium prolonged sleep time experiment, and group C underwent a pentobarbital sodium sleep latency experiment. Each group of mice was further randomly divided into a negative control group, a low-dose group, a medium-dose group, a high-dose group, and a positive control group, with 10 mice in each group. The negative control group was given 180 mg / kg bw saline by gavage, the low-dose group was given 60 mg / kg bw of the combination by gavage, the medium-dose group was given 120 mg / kg bw of the combination by gavage, the high-dose group was given 180 mg / kg bw of the combination by gavage, and the positive control group was given 0.01 mg / kg bw melatonin by gavage. All mice were given gavage once a day at a volume of 0.2 mL / 10 g bw for 30 consecutive days.

[0071] (1) Subthreshold dose sleep experiment of sodium pentobarbital: 30 minutes after the last gavage administration of mice in each group of batch A, each group of mice was injected intraperitoneally with sodium pentobarbital at a dose of 30 mg / kg.bw, with an injection volume of 0.1 mL / 10 g.bw. The number of mice falling asleep in each group was observed and recorded and the sleep incidence rate was calculated. The results are shown in Table 1.

[0072]

[0073] Note: Compared with the negative control group, ** indicates P < 0.01, and * indicates P < 0.05.

[0074] As shown in Table 1, although the effects of low-dose, medium-dose, and high-dose groups on improving the incidence of sleep in mice were weaker than those in the positive control group, the incidence of sleep in the medium-dose and high-dose groups was significantly higher than that in the negative control group. This indicates that ingesting a certain amount of plant-derived sleep aid composition can effectively improve the incidence of sleep in mice.

[0075] (2) Experiment on prolonging the sleep time of sodium pentobarbital: 30 minutes after the last gavage administration of each group of mice in batch B, each group of mice was injected intraperitoneally with 50 mg / kg.bw sodium pentobarbital, with an injection volume of 0.1 mL / 10 g.bw. The sleep duration of each group of mice was observed and recorded. The results are shown in Table 2.

[0076]

[0077] Note: Compared with the negative control group, ** indicates P < 0.01, and * indicates P < 0.05.

[0078] As shown in Table 2, although the low-dose, medium-dose, and high-dose groups had a weaker effect on prolonging the sleep duration of mice than the positive control group, the sleep duration of mice in the medium-dose group was significantly higher than that of the negative control group. This indicates that ingesting a certain amount of plant-derived sleep aid composition can effectively prolong the sleep duration of mice.

[0079] (3) Sodium barbital sleep latency experiment: 30 minutes after the last gavage administration of mice in batch C, mice in each group were injected intraperitoneally with sodium barbital at a dose of 280 mg / kg.bw, with an injection volume of 0.1 mL / 10 g.bw. The sleep latency of mice in each group was observed and recorded. The results are shown in Table 3.

[0080]

[0081] Note: Compared with the negative control group, ** indicates P < 0.01, and * indicates P < 0.05.

[0082] As shown in Table 3, although the low-dose, medium-dose, and high-dose groups were less effective than the positive control group in shortening the sleep latency of mice, the sleep latency of mice in the medium-dose group was significantly shorter than that of the negative control group. This indicates that ingesting a certain amount of plant-derived sleep aid composition can effectively shorten the sleep latency of mice.

[0083] in conclusion

[0084] Based on the results of the sodium pentobarbital subthreshold dose sleep experiment, the sodium pentobarbital prolonged sleep time experiment, and the sodium barbital sleep latency experiment, it can be concluded that the plant-derived sleep aid composition of Example 1 can effectively improve the sleep of mice, increase the incidence of sleep in mice, prolong the sleep duration of mice, and shorten the sleep latency of mice.

[0085] Example 2

[0086] (1) By weight, take 15 parts of jujube seed, 8 parts of poria cocos, 7 parts of wheat, 4 parts of dried ginger and 4 parts of oyster shell, mix them evenly, and stir-fry at 70℃ for 40 minutes to obtain the first material.

[0087] (2) The first material is mixed and ground with 2.5 times its volume of hot water to obtain the first slurry;

[0088] (3) Add 0.2 wt% of deacetylated chitin to the first slurry and stir with nitrogen for 1 h to obtain the second slurry;

[0089] (4) Centrifuge the second slurry and concentrate the collected supernatant by vacuum evaporation to one-third of its original volume to obtain a concentrated liquid;

[0090] (5) Mix the concentrate and aloe vera extract at a volume ratio of 3:1 to obtain a plant-derived sleep aid composition.

[0091] The plant-derived sleep aid composition of Example 2 was prepared into a skin softening lotion: 30% of the plant-derived sleep aid composition, 16% of glycerin, 15% of carbomer, 1.3% of butylene glycol, 1.2% of propylene glycol, 0.8% of caprylyl glycol, 0.5% of vitamin D, 0.3% of vitamin E, and deionized water were added to make up to 100% by mass percentage, and the mixture was stirred and mixed evenly to obtain the skin softening lotion.

[0092] We recruited 40 volunteers (whose sleep monitoring score on Xiaomi Mi Band was below 80) to use this toner before bed for 35 consecutive days, and collected 36 valid user feedback responses.

[0093] All volunteers reported that the product produced a warm sensation, which was very comfortable and made them feel lazy.

[0094] No volunteers experienced any abnormalities such as redness, stinging, itching, burning, or peeling during the use of the product.

[0095] After 10 days of continuous use, three-quarters of the volunteers achieved a sleep monitoring score of 85 or higher; after 20 days of continuous use, all volunteers achieved a sleep monitoring score of 90 or higher; and after 30 days of continuous use, all volunteers' sleep monitoring scores stabilized between 92 and 95.

[0096] in conclusion

[0097] The plant-derived sleep aid composition of Example 2, when applied to cosmetics, can effectively improve people's sleep quality; moreover, it is safe, gentle, and non-irritating.

[0098] The above provides a detailed description of a plant-derived sleep-aiding composition, its preparation method, and its application provided by the embodiments of the present invention. Specific examples have been used to illustrate the principles and implementation methods of the present invention. The descriptions of the above embodiments are only for the purpose of helping to understand the method and core ideas of the present invention. At the same time, for those skilled in the art, there will be changes in the specific implementation methods and application scope based on the ideas of the present invention. Therefore, the content of this specification should not be construed as a limitation of the present invention.

Claims

1. A method for preparing a plant-derived sleep-aiding composition, characterized in that, Includes the following steps: S1. By weight, take 10-20 parts of jujube seed, 6-9 parts of poria cocos, 6-9 parts of wheat, 3-5 parts of dried ginger and 3-5 parts of oyster shell, mix them evenly, and stir-fry at 60-80℃ for 30-50 minutes to obtain the first material. S2. Mix and grind the first material with 2 to 3 times its volume of hot water to obtain the first slurry; S3. Add 0.1-0.3 wt% of deacetylated chitosan to the first slurry and stir with nitrogen for at least 1 hour to obtain the second slurry; S4. The second slurry is centrifuged, and the collected supernatant is concentrated by vacuum evaporation to one-third of its original volume to obtain a concentrated liquid. S5. The concentrated liquid and aloe vera extract are mixed at a volume ratio of 1:5 to 5:1 to obtain a plant-based sleep aid composition.

2. The method for preparing the plant-derived sleep-aiding composition as described in claim 1, characterized in that, Before step S1, the following is also included: Moisten Poria cocos with glutinous rice wine, stir-fry until dry at 80-90℃, and let cool before use; and / or Soak dried ginger in glutinous rice vinegar, stir-fry until dry at 110-120℃, and let cool before use.

3. The method for preparing the plant-derived sleep-aiding composition as described in claim 1, characterized in that, In step S1, before the stir-frying process, the jujube seed, the poria cocos, the wheat, the dried ginger, and the oyster shell are crushed.

4. The method for preparing the plant-derived sleep-aiding composition as described in claim 1, characterized in that, In step S2, the temperature of the hot water is greater than 90°C.

5. The method for preparing the plant-derived sleep-aiding composition as described in claim 1, characterized in that, In step S3, the flow rate of the nitrogen gas is in the range of 50 to 60 cubic decimeters per hour.

6. The method for preparing the plant-derived sleep-aiding composition as described in claim 1, characterized in that, In step S4, the rotation speed range of the centrifugation process is 10,000 to 15,000 rpm.

7. The method for preparing the plant-derived sleep-aiding composition as described in claim 1, characterized in that, In step S5, the aloe extract is a Curacao aloe extract with a purity of 92-99%.

8. The method for preparing the plant-derived sleep-aiding composition as described in claim 1, characterized in that, Step S5 also includes: Cherry extract and banana extract are added to the mixture of the concentrate and the aloe vera extract, wherein the amount of cherry extract added is 5-15 wt% of the mass of the concentrate, and the amount of banana extract added is 10-20 wt% of the mass of the concentrate.

9. A plant-derived composition for aiding sleep, characterized in that, The plant-derived sleep aid composition is prepared by the method of any one of claims 1 to 8.

10. The use of the plant-derived sleep-aiding composition as described in claim 9 in the preparation of sleep-aiding cosmetics or health products, characterized in that: When used in the preparation of cosmetics for aiding sleep, in the plant-derived sleep-aiding composition, the concentrate and the aloe vera extract are mixed in a volume ratio of 5:1 to 5. When used in the preparation of health products to aid sleep, the concentrated liquid and the aloe vera extract are mixed in a volume ratio of 1:1 to 5 in the plant-derived sleep-aiding composition.

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