Oil-control anti-dandruff shampoo and preparation method thereof

Abstract

The invention discloses oil-control and anti-dandruff shampoo and a preparation method thereof, and relates to the technical field of cosmetics. The invention relates to an oil-control and anti-dandruff shampoo, which comprises the following components: sodium lauryl sulfate; cocamidopropyl betaine is added; and lauryl hydroxyl sulphobetaine; an alkyl glycoside; glycerol; a hair conditioner; a thickening agent; a chelating agent; a pH adjusting agent; a pigment; pearly slurry; preparing an SF-1 acrylate copolymer solution; a preservative; lactobacillus powder; a plant extract composition; and the balance of deionized water. The plant extract composition comprises a ginseng root extract, an angelica sinensis extract, a lophatherum gracile extract and a mangosteen peel extract. By optimizing the formula components and proportion, the applicability of the shampoo is expanded, scalp microecological balance is adjusted, scalp grease secretion is controlled, pores blocked by grease are reduced, moisture is provided for scalp, and dandruff caused by microbial disorder, pore blockage and scalp dryness of scalp is solved.

Description

Technical Field

[0001] The invention relates to the technical field of cosmetics, and in particular to an oil-controlling and anti-dandruff shampoo and a preparation method thereof. Background Art

[0002] Dandruff is the product of scalp keratin shedding, and the metabolism of the stratum corneum is a normal physiological phenomenon. When the scalp is in a healthy state, the normal shedding of scalp keratin is less, and after daily regular cleaning, there is almost no visible dandruff. When there is a problem with the health of the scalp, the balance between epidermal cell shedding and cell regeneration is destroyed, causing keratinized cells to aggregate into visible shedding, which is dandruff. A healthy scalp ecological environment is maintained by three major balances: oil, flora, and metabolic balance. When the scalp oil secretion is unbalanced, the scalp will become oily; when the scalp flora environment is unbalanced and harmful bacteria breed in large numbers, itching will occur; and the scalp stratum corneum metabolism is too fast, and dandruff is formed when it falls off. It manifests as an abnormal increase in flaky white scales visible to the naked eye, while skin desquamation is usually scales that are difficult to observe with the naked eye. When a large number of such scales gather together, dandruff will appear.

[0003] In modern society, due to various pressures, irregular work and rest, irregular diet, frequent hair dyeing and perming, etc., people have oily hair and dandruff. As people's work and rest are becoming more and more irregular, they often suffer from insomnia, eat oily and spicy food, frequently dye and perm their hair, and use conditioners improperly, and environmental pollution is becoming more and more serious, which seriously affects the health of the scalp, causing it to be severely damaged, excessive oil secretion, and clogging of hair follicles. Common anti-dandruff agents on the market are:

[0004] 1. Antibiotics, such as piroctone olamine (OCT), climbazole (Climbazole), and zinc pyrithione (ZPT), achieve therapeutic effects by inhibiting or killing fungi and bacteria related to dandruff. They have good dandruff removal effects, but long-term use makes Malassezia develop antibacterial properties.

[0005] 2. Scalp cell growth inhibitors, such as selenium disulfide, can improve dandruff problems by inhibiting cell replication and restoring the normal regeneration cycle length of cells. However, they have a strong smell and are highly irritating. Hair may feel rough after use. If not rinsed thoroughly, the hair may become discolored. A small number of users will experience increased hair loss.

[0006] 3. Use acid to peel off the damaged epidermal cells in the stratum corneum to achieve the purpose of removing dandruff. Generally, it will lead to excessive exfoliation, damage to the scalp barrier, and a series of problems.

[0007] 4. Natural green anti-dandruff agents, such as tea tree oil, soapberry, Sophora flavescens extract, Cnidium monnieri extract, dandelion extract, etc., are natural and green and more popular with consumers, but there are problems such as unclear effects and unstable formulas. Summary of the invention

[0008] The purpose of the present invention is to overcome the deficiencies of the prior art and provide an oil-controlling anti-dandruff shampoo and a preparation method thereof. The present invention optimizes the formula components and ratios to expand the applicability of the shampoo, and while regulating the microecological balance of the scalp, controls the oil secretion of the scalp, reduces oil clogging of pores, provides moisture to the scalp, and solves dandruff caused by scalp microbial imbalance, pore clogging, and dry scalp.

[0009] To achieve the above object, the technical solution adopted by the present invention is:

[0010] In a first aspect, the present invention provides an oil-controlling and anti-dandruff shampoo comprising the following components in percentage by weight:

[0011] Phase A: Sodium lauryl sulfate 8-15%; Cocamidopropyl betaine 1-5%; Lauryl hydroxysultaine 0.1-5%; Alkyl glucoside 1-5%; Glycerin 1-10%;

[0012] Phase B: hair conditioning agent 1-3.2%;

[0013] Phase C: thickener 1-3%; chelating agent 0.01-0.2%; pH adjuster 0.01-0.2%; pigment 0.0001-0.001%; ​​pearlescent paste 3-6%;

[0014] Phase D: SF-1 acrylic copolymer solution 1-6%;

[0015] Phase E: preservative 0.8-1.2%;

[0016] Phase F: Lactobacillus powder 0.7-1.5%;

[0017] Phase G: plant extract composition 0.5-3%;

[0018] The balance is deionized water; the total mass percentage is 100%;

[0019] The plant extract composition comprises ginseng root extract, angelica extract, loquat leaf extract and mangosteen fruit peel extract.

[0020] Lactobacillus powder strengthens hair roots, controls oil production, and improves dandruff by increasing good bacteria on the scalp and inhibiting the growth of bad bacteria on the scalp. On the one hand, Lactobacillus powder inhibits the formation of biofilms of Bacillus dandruff and Staphylococcus aureus, adjusts the microecology of the scalp flora, balances the scalp flora, and maintains scalp health; on the other hand, Lactobacillus powder can inhibit scalp aging caused by peroxides, promote skin fibroblasts and skin keratinocytes, and produce hair growth factors, achieving a balance between flora and metabolism.

[0021] Mangosteen is a fruit that is eaten daily. The mangosteen shell contains a variety of active ingredients, including α-mangostin, xanthones, flavonoids, anthraquinones, hydroxycitric acid, sugars, proteins, inorganic elements, etc. Mangosteen peel extract has soothing and anti-inflammatory effects, can reduce scalp inflammation, improve scalp health, regulate oil secretion, control scalp oil secretion, reduce oil clogging pores, and synergize with lactobacillus powder.

[0022] Angelica extract can significantly inhibit the secretion of inflammatory factors and help improve scalp inflammation. In addition, Angelica extract can inhibit the growth of Malassezia, reduce the excessive proliferation of scalp microorganisms, and reduce the oil secretion of the scalp, thereby alleviating the problem of dandruff.

[0023] Ginseng root is rich in ginsenosides, polysaccharides, vitamins, etc., which promote scalp metabolism.

[0024] The extract of bamboo leaves has excellent anti-free radical, anti-oxidation, anti-aging, antibacterial and antiviral effects. It can protect hair follicles and inhibit the aging of the scalp. The flavonoids in the leaves of bamboo leaves have antibacterial effects.

[0025] Therefore, the present invention adopts lactobacillus powder and a compound plant extract composed of ginseng root, angelica, loblolly leaf and mangosteen to synergistically enhance the anti-dandruff effect. The inhibitory effect on Malassezia is significant, which is beneficial to restore the microecological balance of scalp flora, inhibit oil secretion, reduce the growth of harmful bacteria, maintain scalp health, is natural and safe, solves the dandruff problem from the root, and at the same time makes the product have excellent moisturizing and oil-control effects.

[0026] Preferably, the method for preparing the plant extract composition comprises the following steps:

[0027] (1) Mixing ginseng root, angelica sinensis, lophatherum gracile and mangosteen peel uniformly to obtain a mixture, then crushing the mixture and adding it to a mixed alcohol solution and mixing it uniformly, refluxing for 1-2 hours, filtering and obtaining a first filtrate; the weight ratio of the mixture to the mixed alcohol solution is 1:10;

[0028] (2) reflux the residue 2-3 times to obtain a second filtrate, then combine the first filtrate and the second filtrate, and rotary evaporate the filtrate to a dry extract to obtain the plant extract composition.

[0029] Preferably, in step (1), the weight ratio of the ginseng root, angelica sinensis, lophatherum gracile and mangosteen fruit peel is 2:2:1:2.

[0030] Preferably, in step (1), the mixed alcohol solution comprises methanol and ethanol, and the volume ratio of methanol to ethanol is (0.5-3):1. More preferably, it is 2:1.

[0031] Preferably, the hair conditioning agent includes polyquaternium-10, bis-aminopropyl dimethicone, polyquaternium-7, and guar hydroxypropyltrimonium chloride.

[0032] Preferably, the hair conditioner comprises the following components by weight percentage:

[0033] Polyquaternium-10 0.1-0.3%; Bis-aminopropyl dimethicone 0.2-0.6%; Polyquaternium-7 0.6-2%; Guar hydroxypropyltrimonium chloride 0.1-0.3%.

[0034] Preferably, the thickener comprises the following components by weight: 0.9-2% of food-grade refined salt; 0.1-0.4% of hydroxypropyl methylcellulose.

[0035] Preferably, the preservative is NAGO VLC.

[0036] NAGO VLC is a pure plant antibacterial agent with 100% natural origin. Its main antibacterial active ingredients are lemon fruit extract, cinnamon bark extract, and soybean seed extract. It has a wide antibacterial spectrum and has a good inhibitory effect on bacteria and fungi. Among them, soybean seed extract comes from the grain crop soybean, and cinnamon bark extract comes from cinnamon, a medicinal herb with both medicinal and edible properties. Both are green and natural medicinal materials, naturally extracted, and highly safe.

[0037] Preferably, the lactic acid bacteria powder is Lactobacillus paracasei GMNL-653.

[0038] Lactobacillus paracasei GMNL-653 is a heat-killed dead bacteria strain that improves scalp oiliness and dandruff by adjusting the balance of scalp microecology and restoring the microecological balance of scalp flora.

[0039] In a second aspect, the present invention further provides a method for preparing an oil-controlling and anti-dandruff shampoo, comprising the following steps:

[0040] S1: Mix the raw materials in phase A with deionized water, and stir homogenously until they are completely dissolved to obtain a mixed solution 1;

[0041] S2: adding the raw materials in phase B to the mixed solution 1 and mixing evenly to obtain the mixed solution 2;

[0042] S3: respectively add the raw materials in phase C, phase D, phase E, phase F and phase G into the mixed solution 2, stir evenly and then discharge the materials to obtain the oil-controlling anti-dandruff shampoo.

[0043] Preferably, in step S1, the temperature of the homogenizing stirring is 15-80°C.

[0044] Compared with the prior art, the present invention has the following beneficial effects:

[0045] The purpose of the present invention is to meet the current consumer expectations for natural and mild products, to provide an anti-dandruff shampoo using natural raw materials, which has good anti-dandruff effect, good product stability and simple production. At the same time, the traditional anti-dandruff agent is abandoned, and an inactivated probiotic powder: lactobacillus powder compounded with an oil-controlling anti-dandruff plant extract composition is adopted, which is beneficial to maintaining the balance of hair colonies and oil, keeping the scalp in a healthy state, maintaining normal metabolism, thereby reducing the generation of dandruff. At the same time, natural plant extracts are used as preservatives to improve the safety of the product, and the low-temperature mixing method is used to produce the product to well maintain the good anti-dandruff effect of the product. DETAILED DESCRIPTION

[0046] In order to better illustrate the purpose, technical solutions and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments, but the protection scope and implementation methods of the present invention are not limited thereto.

[0047] Unless otherwise specified, the materials and reagents used in the following examples are commercially available.

[0048] Lactobacillus paracasei GMNL-653 was purchased from Jingyue Biotechnology Co., Ltd.

[0049] SF-1 acrylic copolymer solution was purchased from Foshan Mingyan Biotechnology Co., Ltd.

[0050] Preparation Example 1

[0051] A method for preparing a plant extract composition comprises the following steps:

[0052] (1) Ginseng root, Angelica sinensis, Lophatherum gracile and Mangosteen fruit peel are mixed uniformly in a weight ratio of 2:2:1:2 to obtain a mixture, and then the mixture is crushed and added into a mixed alcohol solution of methanol and ethanol, mixed uniformly, refluxed for 1 hour, and filtered to obtain a first filtrate; the weight ratio of the mixture to the mixed alcohol solution is 1:10; the volume ratio of methanol to ethanol is 0.5:1;

[0053] (2) reflux the residue three times to obtain a second filtrate, then combine the first filtrate and the second filtrate, and rotary evaporate the filtrate to obtain a dry extract to obtain the plant extract composition.

[0054] Preparation Example 2

[0055] The difference from Preparation Example 1 is that in step (1), the volume ratio of methanol to ethanol is 1:1, and the rest is the same as Preparation Example 1.

[0056] Preparation Example 3

[0057] The difference from Preparation Example 1 is that in step (1), the volume ratio of methanol to ethanol is 2:1, and the rest is the same as Preparation Example 1.

[0058] Preparation Example 4

[0059] The difference from Preparation Example 1 is that in step (1), the volume ratio of methanol to ethanol is 3:1, and the rest is the same as Preparation Example 1.

[0060] Preparation Example 5

[0061] The difference from Preparation Example 1 is that in step (1), the mixed alcohol solution is methanol and propylene glycol, and the volume ratio of methanol to propylene glycol is 2:1. The rest is the same as Preparation Example 1.

[0062] Preparation Example 6

[0063] The difference from Preparation Example 1 is that in step (1), the mixed alcohol solution is propylene glycol and ethanol, and the volume ratio of propylene glycol to ethanol is 2:1. The rest is the same as Preparation Example 1.

[0064] Preparation Example 7

[0065] The difference from Preparation Example 1 is that in step (1), the weight ratio of the mixture to the mixed alcohol solution is 1:5, and the rest is the same as Preparation Example 1.

[0066] Preparation Example 8

[0067] The difference from Preparation Example 1 is that in step (1), the weight ratio of the mixture to the mixed alcohol solution is 1:20, and the rest is the same as Preparation Example 1.

[0068] Preparation Example 9

[0069] The difference from Preparation Example 1 is that in step (1), no ginseng root is added to the mixture, and the rest is the same as Preparation Example 1.

[0070] Preparation Example 10

[0071] The difference from Preparation Example 1 is that in step (1), no angelica is added to the mixture, and the rest is the same as Preparation Example 1.

[0072] Preparation Example 11

[0073] The difference from Preparation Example 1 is that in step (1), no loblolly leaves are added to the mixture, and the rest is the same as Preparation Example 1.

[0074] Preparation Example 12

[0075] The difference from Preparation Example 1 is that in step (1), the pericarp of Mangosteen fruit is not added to the mixture, and the rest is the same as Preparation Example 1.

[0076] Example 1

[0077] An oil-controlling and anti-dandruff shampoo comprises the following components in percentage by weight:

[0078] Phase A: Sodium Laureth Sulfate 10%; Cocamidopropyl Betaine 3%; Lauryl Hydroxysulfobetaine 3%; Alkyl Glucoside 2%; Glycerin 3%;

[0079] Phase B: Polyquaternium-10 0.2%, Bis-aminopropyl dimethicone 0.5%, Polyquaternium-7 1%, Guar Hydroxypropyltrimonium Chloride 0.2%;

[0080] Phase C: edible grade refined salt 1.5%; Hydroxypropyl methylcellulose 0.2%; Disodium EDTA 0.05%; Citric acid 0.01%; Food coloring brilliant blue 0.0006%; Pearlescent paste 4%;

[0081] Phase D: SF-1 acrylic copolymer solution 4%;

[0082] Phase E: preservative 1%; the preservative is NAGO VLC;

[0083] Phase F: 1% lactobacillus powder; the lactobacillus powder is Lactobacillus paracasei GMNL-653;

[0084] Phase G: 1.7% of the plant extract composition prepared in Preparation Example 3;

[0085] The balance was deionized water.

[0086] This embodiment also discloses a method for preparing an oil-controlling and anti-dandruff shampoo, comprising the following steps:

[0087] S1: Mix the raw materials in phase A with deionized water, and stir homogenously at 35°C until completely dissolved to obtain a mixed solution 1;

[0088] S2: Add the raw materials in phase B to mixed solution 1 and mix evenly at 35°C to obtain mixed solution 2;

[0089] S3: Add the raw materials in phase C, phase D, phase E, phase F and phase G into the mixed solution 2 respectively, stir at 35° C. for 30 minutes and then discharge the materials to obtain the oil-controlling anti-dandruff shampoo.

[0090] Example 2

[0091] An oil-controlling and anti-dandruff shampoo comprises the following components in percentage by weight:

[0092] Phase A: Sodium Laureth Sulfate 8%; Cocamidopropyl Betaine 5%; Lauryl Hydroxysulfobetaine 5%; Alkyl Glucoside 1%; Glycerin 1%;

[0093] Phase B: Polyquaternium-10 0.1%, Bis-aminopropyl dimethicone 0.2%, Polyquaternium-7 0.6%, Guar Hydroxypropyltrimonium Chloride 0.1%;

[0094] Phase C: 0.9% food grade refined salt; 0.1% hydroxypropyl methylcellulose; 0.2% disodium EDTA; 0.01% citric acid; 0.0001% food coloring brilliant blue; 3% pearlescent paste;

[0095] Phase D: SF-1 acrylic copolymer solution 1%;

[0096] Phase E: 1.2% preservative; the preservative is NAGO VLC;

[0097] Phase F: 0.7% lactobacillus powder; the lactobacillus powder is Lactobacillus paracasei GMNL-653;

[0098] Phase G: 0.5% of the plant extract composition prepared in Preparation Example 3;

[0099] The balance was deionized water.

[0100] The preparation method of an oil-controlling and anti-dandruff shampoo is the same as that of Example 1.

[0101] Example 3

[0102] An oil-controlling and anti-dandruff shampoo comprises the following components in percentage by weight:

[0103] Phase A: Sodium lauryl sulfate 15%; Cocamidopropyl betaine 1%; Lauryl hydroxysultaine 0.1%; Alkyl glucoside 5%; Glycerin 10%;

[0104] Phase B: Polyquaternium-10 0.3%, Bis-aminopropyl dimethicone 0.6%, Polyquaternium-7 2%, Guar Hydroxypropyltrimonium Chloride 0.3%;

[0105] Phase C: 2.5% food grade refined salt; 0.5% hydroxypropyl methylcellulose; 0.01% disodium EDTA; 0.2% citric acid; 0.001% food coloring brilliant blue; 6% pearlescent paste;

[0106] Phase D: SF-1 acrylic copolymer solution 6%;

[0107] Phase E: preservative 0.8%; preservative is NAGO VLC;

[0108] Phase F: 1.5% lactobacillus powder; the lactobacillus powder is Lactobacillus paracasei GMNL-653;

[0109] Phase G: 3% of the plant extract composition prepared in Preparation Example 3;

[0110] The balance was deionized water.

[0111] The preparation method of an oil-controlling and anti-dandruff shampoo is the same as that of Example 1.

[0112] Example 4

[0113] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the plant extract composition is prepared by Preparation Example 1, that is, in step (1), the volume ratio of methanol to ethanol is 0.5:1.

[0114] Example 5

[0115] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the plant extract composition is prepared by Preparation Example 2, that is, in step (1), the volume ratio of methanol to ethanol is 1:1.

[0116] Example 6

[0117] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the plant extract composition is prepared by Preparation Example 4, that is, in step (1), the volume ratio of methanol to ethanol is 3:1.

[0118] Example 7

[0119] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the plant extract composition is prepared by Preparation Example 5, that is, in step (1), the volume ratio of methanol to propylene glycol is 2:1.

[0120] Example 8

[0121] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the plant extract composition is prepared by Preparation Example 6, that is, in step (1), the volume ratio of propylene glycol to ethanol is 2:1.

[0122] Example 9

[0123] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the plant extract composition is prepared by Preparation Example 7, that is, in step (1), the weight ratio of the mixture to the mixed alcohol solution is 1:5.

[0124] Example 10

[0125] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the plant extract composition is prepared by Preparation Example 8, that is, in step (1), the weight ratio of the mixture to the mixed alcohol solution is 1:20.

[0126] Embodiment 11

[0127] A method for preparing an oil-controlling and anti-dandruff shampoo is different from that of Example 1 in that, in step S1, the temperature of homogenizing and stirring is 15°C.

[0128] Example 12

[0129] A method for preparing an oil-controlling and anti-dandruff shampoo is different from that of Example 1 in that, in step S1, the temperature of homogenizing and stirring is 50°C.

[0130] Embodiment 13

[0131] A method for preparing an oil-controlling and anti-dandruff shampoo is different from that of Example 1 in that, in step S1, the temperature of homogenizing and stirring is 70°C.

[0132] Embodiment 14

[0133] A method for preparing an oil-controlling and anti-dandruff shampoo is different from that of Example 1 in that, in step S1, the temperature of homogenizing and stirring is 80°C.

[0134] Comparative Example 1

[0135] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that lactobacillus powder and plant extract composition are not added.

[0136] Comparative Example 2

[0137] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that lactobacillus powder is not added.

[0138] Comparative Example 3

[0139] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that no plant extract composition is added.

[0140] Comparative Example 4

[0141] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the SF-1 acrylic acid ester copolymer solution is not added.

[0142] Comparative Example 5

[0143] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the plant extract composition is prepared by Preparation Example 9, that is, no ginseng root is added.

[0144] Comparative Example 6

[0145] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the plant extract composition is prepared by Preparation Example 10, that is, no angelica is added.

[0146] Comparative Example 7

[0147] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the plant extract composition is prepared by Preparation Example 11, that is, no Lophatherum gracile leaves are added.

[0148] Comparative Example 8

[0149] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the plant extract composition is prepared by Preparation Example 12, that is, no Mangosteen fruit peel is added.

[0150] Comparative Example 9

[0151] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the weight percentage of lactobacillus powder is 0.6%, and the weight percentage of the plant extract composition is 0.4%.

[0152] Comparative Example 10

[0153] An oil-controlling and anti-dandruff shampoo is different from Example 1 in that the weight percentage of lactobacillus powder is 1.7% and the weight percentage of the plant extract composition is 3.5%.

[0154] Effect Example 1

[0155] The oil-controlling and anti-dandruff shampoos prepared in Examples 1-14 of the present invention and Comparative Examples 1-10 were subjected to stability tests.

[0156] Stability test method: Test the samples at high temperature (50°C) for 1 month, low temperature (5°C) for 1 month, and high and low temperature cycles for 3 times (50°C for 3 days; -18°C for 3 days; room temperature for 3 days) for 1 month to observe whether there is stratification or taste or color change. Normal appearance means no stratification or taste or color change. The test results are shown in Table 1.

[0157] Effect Example 2

[0158] The oil-controlling and anti-dandruff shampoos prepared in Examples 1-14 of the present invention and Comparative Examples 1-10 were subjected to an antibacterial test.

[0159] Antibacterial rate test method:

[0160] 1) Dilute the sample to 0.1% with sterile water;

[0161] 2) Add 0.1 mL of Malassezia furfur suspension and mix thoroughly. After 20 minutes of timing, dilute appropriately, take 2-3 dilutions, take 1 mL of each and place in two parallel plates, then add the corresponding culture medium, mix well and culture at 30°C for 4 days. Repeat the above experiment three times, take the average, and set up a blank control;

[0162] 3) After culturing at 30°C for 4 days, count the colonies and calculate the inhibition rate.

[0163] The calculation formula is as follows:

[0164] Antibacterial rate = [(AB) / A]*100

[0165] Wherein, A-the average colony count of the control group; B-the average colony count of the test group; the result is rounded to one decimal place.

[0166] The above test results are shown in Table 1.

[0167] Table 1

[0168]

[0169]

[0170] It can be seen from Table 1 that the oil-controlling and anti-dandruff shampoo prepared by the present invention still has high stability after being placed for 6 months.

[0171] By comparing Examples 4-6 with Example 1, it can be found that when the volume ratio of methanol to ethanol in the mixed alcohol solution is 2:1, the product has the best effect in inhibiting Malassezia.

[0172] By comparing Examples 7-8 with Example 1, it can be found that when the mixed alcohol solution is a mixture of methanol and ethanol, the product has the best effect in inhibiting Malassezia.

[0173] By comparing Examples 9-10 with Example 1, it can be found that when the weight ratio of the mixture to the mixed alcohol solution is 1:10, the product has the best effect in inhibiting Malassezia.

[0174] According to the comparison between Examples 11-14 and Example 1, it can be found that the homogenizing stirring temperature of the raw materials and water in Phase A has little effect on the antibacterial rate of the shampoo, so it can be prepared by a low-temperature mixing method, which simplifies the process and reduces the preparation time, while saving energy consumption.

[0175] According to comparative examples 1-8, the present invention can be compared with embodiment 1 respectively, by using lactobacillus powder to compound the plant extracts composed of ginseng root, angelica, bamboo leaf, and mangosteen, the synergistic anti-dandruff effect is achieved, and its inhibitory effect on Malassezia is significant, which is conducive to restoring the microecological balance of scalp flora, inhibiting oil secretion, reducing the breeding of harmful bacteria, maintaining scalp health, and being natural and safe, and solving the dandruff problem from the root. If any of the substances in lactobacillus powder, ginseng root, angelica, bamboo leaf, and mangosteen are lacking, the shampoo cannot have a higher antibacterial effect. In addition, in comparative example 4, SF-1 acrylic ester copolymer is not added, resulting in a decrease in the stability of the shampoo, and under the condition of high temperature and high and low temperature cycles, the lactobacillus powder for anti-dandruff is precipitated, thereby affecting the anti-dandruff effect of the product.

[0176] By comparing Comparative Examples 9-10 with Example 1, it can be found that by controlling the ratio of lactobacillus powder and the plant extract composition within the scope protected by the present invention, the shampoo can have excellent antibacterial effect and high stability.

[0177] Effect Example 3

[0178] The oil-controlling and anti-dandruff shampoos prepared in Example 1 of the present invention and Comparative Examples 1-3 were tested for their hair care efficacy.

[0179] Test method: The hair care efficacy of oil-control and anti-dandruff shampoo products is evaluated by comparing the combability of hair tresses before and after using the product using human hair tresses in vitro. The hair tresses are placed in an instrument (fibra.one multifunctional hair test system) for combing performance testing, and the total work required for combing before using the product and the total work required after using the product according to the instructions are recorded.

[0180] Use SPSS and other data statistical analysis software to perform statistical analysis on each measurement value. Calculate the initial value and the measurement values ​​at other measurement time points respectively. If the test data is normally distributed, use the paired t test for statistical analysis; if the test data is non-normally distributed, use the rank sum test for statistical analysis. The statistical methods all use two-tailed tests, with a level of α = 0.05. There should be no less than 6 valid data in each group before and after the use of the product. When there is a significant difference in the values ​​of each test indicator before and after the use of the product (p < 0.05), it means that the product is effective; when there is no significant difference in the values ​​of each test indicator before and after the use of the product (p > 0.05), it means that the product is not effective.

[0181] The test results are shown in Table 2:

[0182] Table 2

[0183]

[0184] According to Table 2, the hair combing performance of the oil-control anti-dandruff shampoo of Example 1 is compared with that before use. The total work done by combing after using the product is reduced by 64.48% compared with that before use, which is significantly different from that before use (p < 0.05). The hair combing performance after using the product is better than that before use. It can be seen that the oil-control anti-dandruff shampoo of the present invention has excellent hair care effect.

[0185] Effect Example 4

[0186] The oil-controlling and anti-dandruff shampoos prepared in Examples 1-3 of the present invention and Comparative Examples 9-10 were subjected to safety tests.

[0187] Test samples: the oil-control and anti-dandruff shampoos of Examples and Comparative Examples.

[0188] Negative control: blank control.

[0189] Subjects: A total of 120 subjects, including 53 males and 67 females, aged 18 to 56 years old, met the voluntary inclusion criteria.

[0190] Test method: Select qualified patch test equipment and use the closed patch test method. Place 0.025g of test sample in the patch tester and apply it to the flexor side of the subject's forearm with low-allergenic tape. Remove the test sample after 24 hours of testing and observe the skin reaction at 0.5h, 24h, and 48h after removal. Record the results according to the skin reaction grading standards in the "Technical Specifications for Safety of Cosmetics" (2015 edition).

[0191] The test results are shown in Table 3 below.

[0192] Table 3

[0193]

[0194] It can be seen from Table 3 that the oil-controlling and anti-dandruff shampoos prepared in the examples of the present invention and the comparative examples did not cause any adverse skin reactions among 100 people.

[0195] Effect Example 5

[0196] In order to further explore the oil-controlling and anti-dandruff efficacy of the oil-controlling and anti-dandruff shampoo of the present invention, the oil-controlling and anti-dandruff shampoo of Examples 1-3 of the present invention and Comparative Examples 1-3 were subjected to a crowd trial effect evaluation test.

[0197] Crowd trial effect evaluation test method

[0198] Age of trial population: 18 to 56 years old;

[0199] Hair problems: dandruff, oily hair;

[0200] Number of trial participants: 180, including 82 males and 98 females;

[0201] Shampooing cycle: once every 3 days; Trial time: 1 month;

[0202] How to wash your hair: After wetting your hair, apply 10.46g of shampoo and gently massage for 5 minutes, then rinse with clean water. Use once.

[0203] The test results are shown in Table 4.

[0204] Table 4

[0205]

[0206] It can be seen from Table 4 that after using the product of Example 1 for one month, 96.7% of the people felt that the product had an oil control effect; and 96.7% of the people felt that the product had an anti-dandruff effect after using it for one month. It can be seen that the oil control and anti-dandruff shampoo of the present invention has good oil control and anti-dandruff efficacy.

[0207] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention rather than to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the essence and scope of the technical solution of the present invention.

Claims

1. An oil-control anti-dandruff shampoo, characterized in that: The composition includes the following weight percentages: Phase A: Sodium lauryl sulfate 8-15%; Cocamidopropyl betaine 1-5%; Lauryl hydroxysultaine 0.1-5%; Alkyl glucoside 1-5%; Glycerin 1-10%; Phase B: hair conditioning agent 1-3.2%; Phase C: thickener 1-3%; chelating agent 0.01-0.2%; pH adjuster 0.01-0.2%; pigment 0.0001-0.001%; ​​pearlescent paste 3-6%; Phase D: SF-1 acrylic copolymer solution 1-6%; Phase E: preservative 0.8-1.2%; Phase F: Lactobacillus powder 0.7-1.5%; Phase G: plant extract composition 0.5-3%; The balance is deionized water; The plant extract composition comprises ginseng root extract, angelica extract, loquat leaf extract and mangosteen fruit peel extract.

2. The oil-control anti-dandruff shampoo according to claim 1, characterized in that: The preparation method of the plant extract composition comprises the following steps: (1) Mixing ginseng root, angelica sinensis, loblolly leaf, and mangosteen peel uniformly to obtain a mixture, then crushing the mixture and adding it to a mixed alcohol solution to mix uniformly, refluxing for 1-2 hours, filtering, and obtaining a first filtrate; the weight ratio of the mixture to the mixed alcohol solution is 1:(5-20); (2) reflux the residue 2-3 times to obtain a second filtrate, then combine the first filtrate and the second filtrate, and rotary evaporate the filtrate to a dry extract to obtain the plant extract composition.

3. The oil-control anti-dandruff shampoo according to claim 2, characterized in that: In step (1), the weight ratio of the ginseng root, angelica sinensis, lophatherum gracile and mangosteen fruit peel is 2:2:1:

2.

4. The oil-control anti-dandruff shampoo according to claim 2, characterized in that: In step (1), the mixed alcohol solution includes methanol and ethanol, and the volume ratio of methanol to ethanol is (0.5-3):

1.

5. The oil-control anti-dandruff shampoo according to claim 1, characterized in that: The hair conditioning agent includes polyquaternium-10, bis-aminopropyl dimethicone, polyquaternium-7, and guar hydroxypropyltrimonium chloride.

6. The oil-control and anti-dandruff shampoo according to claim 5, characterized in that: The hair conditioner comprises the following components by weight percentage: Polyquaternium-10 0.1-0.3%, bis-aminopropyl dimethicone 0.2-0.6%, polyquaternium-7 0.6-2%, guar hydroxypropyltrimonium chloride 0.1-0.3%.

7. The oil-control anti-dandruff shampoo according to claim 1, characterized in that: The thickener comprises the following components by weight percentage: 0.9-2% of food-grade refined salt and 0.1-0.4% of hydroxypropyl methylcellulose.

8. The oil-control anti-dandruff shampoo according to claim 1, characterized in that: The preservative is NAGO VLC, and the lactic acid bacteria powder is Lactobacillus paracasei GMNL-653.

9. The method for preparing the oil-controlling anti-dandruff shampoo according to any one of claims 1 to 8, characterized in that: The following steps are involved: S1: Mix the raw materials in phase A with deionized water, and stir homogenously until they are completely dissolved to obtain a mixed solution 1; S2: adding the raw materials in phase B to the mixed solution 1 and mixing evenly to obtain the mixed solution 2; S3: respectively add the raw materials in phase C, phase D, phase E, phase F and phase G into the mixed solution 2, stir evenly and then discharge the materials to obtain the oil-controlling anti-dandruff shampoo.

10. The method for preparing the oil-controlling anti-dandruff shampoo according to claim 9, characterized in that: In step S1, the temperature of the homogenizing and stirring is 15-80°C.

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