Cosmetic base

Abstract

The present invention provides a novel cosmetic base which achieves both a feeling of use and a moisturizing effect. A cosmetic base agent comprising a polymer having a structure represented by formula (1) or comprising a polymer having a structure represented by formula (1) in which R1 is a C1-4 alkyl group, R2 and R3 are each independently a hydrogen atom or a C1-4 alkyl group, and m and n are each independently 1-50, the polymer having a number average molecular weight of 10,000 or less, and the polymer having a structure represented by formula (1) in which m and n are each independently a hydrogen atom or a C1-4 alkyl group. And the IOB value of the polymer is 0.4 to 1.8. # imgabs0 #

Description

Technical Field

[0001] The present invention relates to cosmetic bases. Background Art

[0002] In order to maintain healthy skin, moisture retention is indispensable, and a large number of cosmetics have been developed for the purpose of moisturizing. In addition, as a feeling of use of cosmetics, it is required to have a moist feeling and no sticky feeling.

[0003] Hitherto, various cosmetics or cosmetic bases have been developed for the purpose of moisturizing.

[0004] For example, Patent Document 1 discloses a moisturizing agent containing a polyether represented by the general formula (1):

[0005] -[X] m -[Y] n - (1)

[0006] 〔In the formula, m X represents a base (X 1 ) or (X 2 ), n Y represents a source capable of reacting with epoxide (x 1 ) or (x 2 ) is a group of copolymerizable monomers, wherein m and n represent numbers satisfying m / (m+n)=0.2 to 1 and m+n≥12.

[0007]

[0008] (R 1 ~R 3 is H, Me or Et, R 4 H or C1~C 32 A hydrocarbon group, a is 1 or 2, R 5 ~R 8 is H, -COOH, -CH2COOH or a salt thereof. 5 =R 6 =R 7 =R 8 =Except H)

[0009] In addition, Patent Document 2 discloses a skin external preparation containing an oxyalkylene derivative represented by the following general formula (I):

[0010] R 1 O-[(AO) m (EO) n ]-R 2 (I)

[0011] (In the formula, AO is an oxyalkylene group having 3 to 4 carbon atoms, EO is an oxyethylene group, m and n are the average added molar numbers of the above-mentioned oxyalkylene group and oxyethylene group, 1≤m≤70, 1≤n≤70. The ratio of oxyethylene group to the total of oxyalkylene group having 3 to 4 carbon atoms and oxyethylene group is 20 to 80% by weight. The oxyalkylene group having 3 to 4 carbon atoms and oxyethylene group may be added in a block form or randomly. R 1 , R 2 is a hydrocarbon group having 1 to 4 carbon atoms, which may be the same or different, or a hydrogen atom, the number of hydrogen atoms being relative to R 1 and R 2 The ratio of the number of hydrocarbon groups is 0.15 or less.)

[0012] Prior art literature

[0013] Patent Literature

[0014] Patent Document 1: Japanese Patent Application Publication No. 2001-048772

[0015] Patent Document 2: Japanese Patent Application Publication No. 2004-083541 Summary of the invention

[0016] Problems to be solved by the invention

[0017] However, for example, the moisturizing agent disclosed in the above-mentioned Patent Document 1 is according to the above-mentioned general formula (1) (-[X] m -[Y] n -) may not provide satisfactory feeling in use as a cosmetic.

[0018] The present invention aims to improve the above situation, and an object of the present invention is to provide a new cosmetic base that achieves both a good feeling during use and a moisturizing effect.

[0019] Means for solving problems

[0020] The present invention for achieving the above-mentioned object is as follows.

[0021] <Scheme 1>

[0022] A cosmetic base comprising a polymer having a structure represented by the following formula (1) or consisting of a polymer having a structure represented by the following formula (1),

[0023]

[0024] In the above formula (1), R 1 is an alkyl group having 1 to 4 carbon atoms, R 2 and R 3are each independently a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, and m and n are each independently 1 to 50,

[0025] The number average molecular weight of the polymer is 10,000 or less, and

[0026] The IOB value of the above polymer is 0.4 to 1.8.

[0027] <Scheme 2>

[0028] According to the cosmetic base of embodiment 1, the polymer is a random copolymer.

[0029] <Scheme 3>

[0030] According to the cosmetic base of embodiment 1 or 2, in the above formula (1), R 1 It is methyl or ethyl.

[0031] <Scheme 4>

[0032] The cosmetic base according to any one of embodiments 1 to 3, wherein in the above formula (1), R 2 and R 3 At least one of them is methyl.

[0033] <Scheme 5>

[0034] The cosmetic base according to any one of aspects 1 to 4, which is a moisturizing cosmetic base.

[0035] <Scheme 6>

[0036] A cosmetic comprising the cosmetic base according to any one of embodiments 1 to 5.

[0037] Effects of the Invention

[0038] According to the present invention, a new cosmetic base which achieves both good feeling during use and moisturizing effect can be provided. DETAILED DESCRIPTION

[0039] Hereinafter, embodiments of the present invention will be described in detail. It should be noted that the present invention is not limited to the following embodiments, and various modifications can be made within the scope of the gist of the invention.

[0040] 《Cosmetic bases》

[0041] The cosmetic base of the present invention comprises a polymer having a structure represented by the following formula (1) or is composed of a polymer having a structure represented by the following formula (1):

[0042]

[0043] In formula (1), R 1is an alkyl group having 1 to 4 carbon atoms, R 2 and R 3 are each independently a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, and m and n are each independently 1 to 50,

[0044] The number average molecular weight of the polymer is 10,000 or less, and

[0045] The IOB value of the polymer is 0.4 to 1.8.

[0046] Through intensive studies by the present inventors, it has been found that the cosmetic base of the present invention can have both a good feeling during use and a moisturizing effect by containing a polymer having a structure represented by the above formula (1) (hereinafter also referred to as "the polymer of the present invention") or consisting of the polymer of the present invention.

[0047] Although not limited by theory, it is presumed that this is because the polymer of the present invention has a unique structure represented by the above formula (1), a number average molecular weight within a specific range (10,000 or less), and an IOB (Inorganic Organic Balance) value within a specific range (0.4 to 1.8).

[0048] It should be noted that the cosmetic base of the present invention may contain water, antioxidants such as tocopherol, preservatives such as phenoxyethanol, etc. as components other than the polymer of the present invention, or may be composed only of the polymer of the present invention. In the case where the cosmetic base of the present invention contains components other than the polymer of the present invention, the content thereof may be 50% by mass or less, 40% by mass or less, 30% by mass or less, 20% by mass or less, 10% by mass or less, 5% by mass or less, or 1% by mass or less.

[0049] In addition, the feeling of use brought about by the cosmetic base of the present invention was comprehensively judged based on "moist feeling", "sticky feeling", "ease of blending and spreading on the skin", and "slippery feeling".

[0050] It should be noted that, in the following description, unless otherwise specified, the phrases such as "Formula (1)" are not formulas in prior art documents, but refer to chemical formulas related to the present invention.

[0051] The polymer of the present invention has a structure represented by the following formula (1):

[0052]

[0053] In formula (1), R 1 is an alkyl group having 1 to 4 carbon atoms, R 2 and R 3Each independently represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms. In addition, in the present invention, examples of the alkyl group having 1 to 4 carbon atoms include methyl, ethyl, n-propyl, isopropyl, n-butyl, sec-butyl, and tert-butyl. In addition, these alkyl groups may further have a substituent as long as the effect of the present invention is not impaired. As the substituent, there is no particular limitation, and examples thereof include a halo group.

[0054] According to one embodiment of the present invention, in formula (1), R 1 It may be methyl, ethyl, n-propyl, isopropyl, n-butyl, sec-butyl, or tert-butyl.

[0055] According to one embodiment of the present invention, in formula (1), R 1 It is preferably a methyl group or an ethyl group, and more preferably an ethyl group.

[0056] According to one embodiment of the present invention, in formula (1), R 2 and R 3 They may each independently be a hydrogen atom, a methyl group, an ethyl group, an n-propyl group, an isopropyl group, an n-butyl group, a sec-butyl group, or a tert-butyl group.

[0057] According to one embodiment of the present invention, in formula (1), R 2 A hydrogen atom, a methyl group or an ethyl group is preferred, and a methyl group is more preferred.

[0058] According to one embodiment of the present invention, in formula (1), R 2 The hydrogen atom and the alkyl group having 1 to 4 carbon atoms may be present in a mixed state. 2 A part of the group is a hydrogen atom, and the other part is an alkyl group having 1 to 4 carbon atoms. 2 A portion of them are hydrogen atoms, and the other portion are methyl groups.

[0059] According to one embodiment of the present invention, in formula (1), R 3 A hydrogen atom, a methyl group or an ethyl group is preferred, and a methyl group is more preferred.

[0060] According to one embodiment of the present invention, in formula (1), R 2 and R 3 At least one of them is preferably a methyl group.

[0061] In formula (1), m and n represent the average number of added moles of each constituent unit. m and n are each independently 1.0 to 50, more specifically, 1.0 or more, 2.0 or more, 3.0 or more, 4.0 or more, 5.0 or more, 6.0 or more, 7.0 or more, 8.0 or more, 9.0 or more, or 10 or more, and 50 or less, 45 or less, 40 or less, 35 or less, 30 or less, 25 or less, 20 or less, 15 or less, 12 or less, 10 or less, 8.0 or less, or 6.0 or less.

[0062] In formula (1), m is preferably 2.0 to 15, more preferably 3.0 to 10. In formula (1), n ​​is preferably 2.0 to 10, more preferably 2.0 to 6.0.

[0063] According to one embodiment of the present invention, in formula (1), m+n can be greater than 4.0, greater than 5.0, greater than 6.0, greater than 7.0, greater than 8.0, greater than 9.0, greater than 10, greater than 11, greater than 12, greater than 13, greater than 14, or greater than 15, and can also be less than 50, less than 45, less than 40, less than 35, less than 30, less than 25, less than 20, less than 15, or less than 12.

[0064] According to one embodiment of the present invention, in formula (1), n:m may be 1:10 to 10:1.

[0065] The number average molecular weight of the polymer of the present invention is 10,000 or less. More specifically, the number average molecular weight of the polymer of the present invention may be, for example, 10,000 or less, 5,000 or less, 3,500 or less, 3,000 or less, 2,500 or less, 2,000 or less, 1,500 or less, 1,400 or less, 1,300 or less, 1,200 or less, 1,100 or less, 1,000 or less, 900 or less, 800 or less, 700 or less, or 600 or less, and may be 130 or more, 150 or more, 200 or more, 250 or more, 300 or more, 350 or more, 400 or more, 450 or more, or 500 or more. In addition, the number average molecular weight of the polymer of the present invention is preferably 300 or more and 3,500 or less, and more preferably 500 or more and 1,200 or less.

[0066] The IOB value of the polymer of the present invention is 0.4 to 1.8. More specifically, the IOB value of the polymer of the present invention may be, for example, 0.4 or more, 0.5 or more, 0.6 or more, 0.7 or more, 0.8 or more, or 0.9 or more, and may be 1.8 or less, 1.6 or less, 1.4 or less, 1.2 or less, or 1.0 or less. In addition, the IOB value of the polymer of the present invention is preferably 0.7 or more and 1.2 or less.

[0067] Here, the so-called IOB value is an abbreviation of Inorganic / Organic Balance, which is a value indicating the ratio of the inorganic value to the organic value, and becomes an indicator of the degree of polarity of the organic compound. The IOB value is specifically expressed as IOB value = inorganic value / organic value. Regarding the "inorganic value" and "organic value", for example, for one carbon atom in a molecule, its "organic value" is 20, and for one hydroxyl group, its "inorganic value" is 100, the "inorganic value" and "organic value" corresponding to various atoms or functional groups are set, and the "inorganic value" and "organic value" of all atoms and functional groups in the organic compound are accumulated, so that the IOB value of the organic compound can be calculated (see, for example, Yoshio Koda, "Organic Concept Map - Foundation and Application - (Organic Concept Map - Foundation and Application -)", p. 11-17, Sankyo Publishing, published in 1984). In addition, regarding the method of determining the IOB value, reference may be made to the method described in the Examples.

[0068] The polymer of the present invention may be a block copolymer or a random copolymer, but is preferably a random copolymer.

[0069] The method for producing the polymer of the present invention is not particularly limited, and can be carried out, for example, by addition polymerization of epoxides corresponding to the respective constituent units. The addition polymerization may be block polymerization or random polymerization, but random polymerization is preferred.

[0070] One of the characteristics of the polymer of the present invention is that it has both high water solubility and high fat solubility.

[0071] The solubility of the polymer of the present invention in water can be, for example, 10% by mass or more, 20% by mass or more, 30% by mass or more, 40% by mass or more, or 50% by mass or more.

[0072] In addition, as an indicator of the fat solubility of the polymer of the present invention, for example, the solubility in olive oil can be used. The solubility of the polymer of the present invention in olive oil can be, for example, 0.01% by mass or more, 0.05% by mass or more, 0.10% by mass or more, 0.50% by mass or more, or 1.00% by mass or more. It should be noted that the upper limit of the solubility of the polymer of the present invention in olive oil is not particularly limited, and can be, for example, 10% by mass or less.

[0073] Due to the above characteristics of the polymer of the present invention, it can be used as a substitute for the oxyalkylene derivative of, for example, Patent Document 2. That is, the cosmetic base containing the polymer of the present invention can be used for moisturizing.

[0074] "cosmetic"

[0075] The present invention further provides a cosmetic product comprising the cosmetic base according to the invention.

[0076] The content of the cosmetic base of the present invention in the cosmetic of the present invention is not particularly limited. For example, the polymer of the present invention may be in an amount of 0.001 to 90% by mass, 0.1 to 50% by mass, or 0.1 to 20% by mass, or further may be 0.1 to 10% by mass in the entire cosmetic. More specifically, for example, the polymer of the present invention may be 0.001 mass% or more, 0.005 mass% or more, 0.01 mass% or more, 0.05 mass% or more, 0.1 mass% or more, 0.5 mass% or more, 1.0 mass% or more, 1.5 mass% or more, or 2.0 mass% or more, and may be 90 mass% or less, 80 mass% or less, 70 mass% or less, 60 mass% or less, 50 mass% or less, 40 mass% or less, 30 mass% or less, 20 mass% or less, 10 mass% or less, 9.0 mass% or less, 8.0 mass% or less, 7.0 mass% or less, 6.0 mass% or less, 5.0 mass% or less, 4.0 mass% or less, 3.0 mass% or less, 2.0 mass% or less, or 1.0 mass% or less, relative to the entire cosmetic.

[0077] The cosmetic of the present invention may further contain, in addition to the cosmetic base of the present invention, one or more components generally used in external skin preparations such as cosmetics and pharmaceuticals as other components.

[0078] Specific examples of other ingredients include powder components, liquid oils, solid oils, waxes, hydrocarbons, higher fatty acids, higher alcohols, esters, silicones, anionic surfactants, cationic surfactants, amphoteric surfactants, nonionic surfactants, water-soluble polymers, thickeners, film-forming agents, ultraviolet absorbers, metal ion blocking agents, lower alcohols, polyols, sugars, amino acids, organic amines, polymer emulsions, pH modifiers, skin nutrients, vitamins, antioxidants, antioxidant aids, fragrances, water, etc., but are not limited to these.

[0079] The dosage form of the cosmetic of the present invention is not particularly limited, and may be, for example, a solution system, a solubilization system, an emulsion system, a powder dispersion system, a water-oil two-layer system, a water-oil-powder three-layer system, a gel, a mist, a spray, a mousse, a roller ball, or a stick, or may be a preparation impregnated or coated on a sheet such as a non-woven fabric, etc.

[0080] In addition, the product form of the cosmetics of the present invention is not particularly limited, and can be, for example, facial cosmetics such as lotions, emulsions, creams, and facial masks; color cosmetics such as foundations, lipsticks, and eye shadows; sunscreen cosmetics (sunscreen agents); body cosmetics; aromatic cosmetics; skin cleansing materials such as makeup removers and body shampoos; hair cosmetics such as shampoos, hair tonics, conditioners, shampoos, conditioners, and hair growth materials; or ointments, etc.

[0081] Example

[0082] The present invention will be described in further detail below with reference to Examples, but the present invention is not limited to these.

[0083] 《Synthesis Examples 1 and 2》

[0084] The following Synthesis Examples 1 and 2 respectively synthesized polymers having the structure shown in the following formula (1):

[0085]

[0086] It should be noted that in formula (1), [ ] represents a random copolymer.

[0087] <Synthesis example 1>

[0088] Synthesis Example 1: R 1 =CH2CH3, R 2 =H, R 3 =CH3, m=4.0, and n=2.0 polymer 1

[0089] 64 g of methanol and 3.3 g of potassium hydroxide as a catalyst were added to an autoclave, and after replacing the air in the autoclave with dry nitrogen, the catalyst was completely dissolved at 80°C while stirring. Next, a mixture of 817 g of ethyl glycidyl ether and 296 g of glycidol was added dropwise over 30 hours through a dropping device, and then stirred for 5 hours. The reaction composition was taken out of the autoclave, neutralized with hydrochloric acid to a pH of 6 to 7, and reduced to -0.095 MPa (50 mmHg) to remove the contained water, and treated at 100°C for 1 hour. In order to further remove the salt generated after the treatment, filtration was performed to obtain 1120 g of polymer 1.

[0090] Various physical property values ​​of the obtained polymer 1 were determined below.

[0091] (Number average molecular weight)

[0092] The number average molecular weight of the obtained polymer 1 was calculated by gel permeation chromatography (GPC). The system was SHODEX (registered trademark) GPC101 GPC dedicated system, the differential refractometer was SHODEX RI-71s, the protective column was SHODEX KF-G, and as the column, three HODEX KF804L were installed in succession, the column temperature was 40°C, tetrahydrofuran was flowed at a flow rate of 1 ml / min as the developing solvent, 0.1 ml of a 0.1 wt% tetrahydrofuran solution of the obtained reactant was injected, and a chromatogram represented by refractive index intensity and elution time was obtained using the BORWIN GPC calculation program. From the chromatogram, the number average molecular weight was calculated using polyethylene glycol as the standard, and the result was 650.

[0093] (IOB value)

[0094] The IOB value of the obtained polymer 1 was determined as follows and found to be 1.04.

[0095] More specifically, in polymer 1, the organic value was calculated by assuming that carbon was 20 and that iso-branched chain was −10. In addition, the inorganic value was calculated by assuming that hydroxyl group was 100 and that ether bond was 20.

[0096] ·Methanol site: (1 carbon atom, 1 hydroxyl group) x 1

[0097] Organic value: 20

[0098] Inorganicity value: 100

[0099] · Glycidol site: (3 carbon atoms, 1 iso-branch, 1 hydroxyl group, 1 ether bond) × 2

[0100] Organic value: (60-10)×2=100

[0101] Inorganicity value: (100+20)×2=240

[0102] ·Ethyl glycidyl ether part: (carbon atoms 5, iso-branch 1, ether bond 2) × 4

[0103] Organic value: (100-10)×4=360

[0104] Inorganic value: 20×2×4=160

[0105] In the above, since the total organic value is 480 and the total inorganic value is 500, the IOB value is 1.04.

[0106] (Cloud Point)

[0107] A 5 wt % aqueous solution of the obtained polymer 1 was prepared and heated to 85° C. The temperature at which the transparent solution became was 57° C. Therefore, it was found that the cloud point of the polymer 1 was 57° C.

[0108] (Solubility in water)

[0109] The solubility of the obtained polymer 1 in water was determined by the following method and the result was 50% by mass or more.

[0110] Specifically, polymer 1 was mixed with water at a certain concentration, stirred, and left to stand for 1 day to determine whether the mixture was compatible. In the case of polymer 1, it was confirmed that the mixture was compatible with water at a concentration of 50% by mass.

[0111] (Solubility in olive oil)

[0112] The solubility of the obtained polymer 1 in olive oil was determined by the following method and the result was 1.0% by mass.

[0113] That is, polymer 1 was mixed with olive oil at a concentration of 1.0 mass %, stirred, and allowed to stand for 1 day to confirm the appearance by visual observation. If it was uniform, it was set to "0". In this case, the solubility of polymer 1 in olive oil was 1.0 mass %.

[0114] The various physical property values ​​of the polymer 1 measured above are shown in Table 1 below.

[0115] <Synthesis example 2>

[0116] Synthesis Example 2: R 1 =CH2CH3, R 2 =H, R 3 =CH3, m=10, and n=5.0 polymer 2

[0117] 32 g of methanol and 3.3 g of potassium hydroxide as a catalyst were added to an autoclave, and after replacing the air in the autoclave with dry nitrogen, the catalyst was completely dissolved at 80°C while stirring. Next, a mixture of 1021 g of ethyl glycidyl ether and 370 g of glycidol was added dropwise over 30 hours through a dropping device, and then stirred for 5 hours. The reaction composition was taken out of the autoclave, neutralized with hydrochloric acid to a pH of 6 to 7, and reduced to -0.095 MPa (50 mmHg) to remove the contained water, and treated at 100°C for 1 hour. In order to further remove the salt generated after the treatment, filtration was performed to obtain 1351 g of polymer 2.

[0118] Various physical property values ​​of the obtained polymer 2 were determined in the same manner as in the case of the above-mentioned polymer 1. The respective results are shown in Table 1 below.

[0119] Table 1

[0120]

[0121] *1 The synthesized polymer was mixed with olive oil at a concentration of 1.0 mass %, and the appearance was checked.

[0122] Set to "o" if uniform.

[0123] 《Examples 1 and 2, and Comparative Example 1》

[0124] In Examples 1 and 2, cosmetic bases 1 and 2 composed of the above polymers 1 and 2 were used to prepare lotions. The feeling of use and moisturizing effect of each lotion were investigated as follows. The respective results are shown in Table 3.

[0125] In addition, in Comparative Example 1, the feeling during use and the moisturizing effect were investigated in the same manner as in the above-mentioned Examples, except that glycerin was increased in place of the polymer.

[0126] <User experience evaluation>

[0127] The use feeling of each lotion prepared as described above was comprehensively evaluated based on "moist feeling", "sticky feeling", "easy blending and spreading on the skin", and "slippery feeling". It should be noted that the evaluation was performed by applying each lotion on the skin and by two professional panelists according to the criteria shown in Table 2 below.

[0128] Table 2 (Table 2 Evaluation criteria for feeling of use)

[0129]

[0130] 〈Moisturizing effect evaluation〉

[0131] To evaluate the moisturizing effect of each lotion prepared above, the lotion was evenly applied on the skin, and then two professional panelists evaluated the moisturizing feeling of the skin. It should be noted that the evaluation levels are as follows:

[0132] “A”: High moisturizing effect is felt;

[0133] “B”: Some degree of moisturizing effect is felt;

[0134] "C": Although the moisturizing effect is felt, it is slightly insufficient.

[0135] Table 3

[0136]

[0137] As is clear from the results in Table 3, the lotions of Examples 1 and 2 are both excellent in feeling during use and moisturizing effect. In contrast, it is found that the lotion of Comparative Example 1 is inferior in feeling during use and moisturizing effect.

Claims

1. A cosmetic base comprising or consisting of a polymer having a structure represented by the following formula (1), In the formula (1), R 1 is an alkyl group having 1 to 4 carbon atoms, R 2 and R 3 are each independently a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, and m and n are each independently 1 to 50, The number average molecular weight of the polymer is 10,000 or less, and The IOB value of the polymer is 0.4 to 1.

8. The cosmetic base according to claim 1 , wherein the polymer is a random copolymer.

3. The cosmetic base according to claim 1 or 2, wherein in the formula (1), R 1 It is methyl or ethyl.

4. The cosmetic base according to claim 1 or 2, wherein in the formula (1), R 2 and R 3 At least one of them is methyl.

5. The cosmetic base according to claim 1 or 2, which is a moisturizing cosmetic base. A cosmetic comprising the cosmetic base according to claim 1 or 2.

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