Intestinal flora detection device and detection method thereof

Abstract

The intestinal flora detection device comprises a probe main body, a first connecting part, a second connecting part, an enteroscope insertion tube and an expansion cover assembly, a supporting sleeve and an inflation balloon are arranged on the outer side of the second connecting part, the probe main body is provided with a camera structure and multiple groups of air ports, two groups of heating wires are arranged on the inner wall of the probe main body, and the two groups of heating wires are arranged on the inner wall of the probe main body. According to the device, the anus of an examiner can be expanded and fixed through the expansion cover assembly, an enteroscope insertion tube can penetrate into the anus conveniently, meanwhile, by arranging a heating wire, a supporting sleeve, an inner inflation balloon, an air port and an air pipe, temperature-controllable, air-controllable and expandable real-time examination of intestinal flora is achieved, the method is simple and practical, and the examination efficiency is improved. And meanwhile, the probe main body can conveniently, controllably and flexibly inspect the interior of the intestinal tract of an inspector.

Description

Technical Field

[0001] The present invention relates to the technical field related to intestinal flora detection, and in particular to an intestinal flora detection device and a detection method thereof. Background Art

[0002] For anorectal testing, the commonly used testing equipment is a colonoscope. The colonoscope is a slender, flexible tube with a diameter of about 1 cm. The colonoscope enters the rectum through the anus and goes to the large intestine. It is connected to an external computer for inspection and data storage, allowing doctors to observe the internal conditions of the colon and large intestine. There are intestinal flora in the intestine, such as Bacteroides fragilis, Escherichia coli, Streptococcus bovis, Enterococcus faecalis, etc. Once the intestinal flora is out of balance, it will affect the physiological functions of the body and lead to the occurrence of diseases. The above bacteria have been proven to promote the occurrence of CRC disease (colorectal cancer), that is, there is a close connection between the imbalance of intestinal flora and the occurrence and development of CRC disease. Therefore, people cannot ignore the detection of intestinal flora.

[0003] Colonoscopy is the standard for diagnosing intestinal diseases. It can directly observe lesions in the intestine and perform biopsies. Existing technologies for intestinal flora detection mainly rely on sampling or culturing intestinal contents, followed by sequencing methods to obtain the results. This has disadvantages such as long time, low efficiency, and insufficient accuracy in one test.

[0004] In addition, the dynamic changes of intestinal flora also make it difficult for the results of a single examination to reflect the patient's true health status. The existing technology does not have a technology that can be combined with colonoscopy to conduct real-time screening and detection of intestinal flora in the intestine. Therefore, a method is designed to use colonoscopy to check the intestinal conditions in different temperature control states, inflation states or different expansion states in real time to form a real-time intestinal flora detection and screening, so as to further improve the accuracy of intestinal flora sequencing detection, that is, to design to intervene and detect in real time during the colonoscopy with different temperature control states, inflation states or different expansion states or to apply inhibitors to obtain intestinal video and microscopic information for real-time screening and detection, and then determine the specific location in the intestine and the temperature state to collect intestinal content samples, or to take intestinal contents after multiple combined in vivo tests and then provide them for high-throughput sequencing analysis or fluorescent quantitative PCR analysis or other detection analysis to ensure accuracy and improve efficiency;

[0005] Furthermore, the existing colonoscopy cannot be used for the above-mentioned intestinal screening or detection of intestinal flora. First, it cannot perform real-time screening or comparative detection under different temperature states and different expansion states to obtain more accurate detection data (video and microscopic information), and it cannot realize multi-functional means at the same time. Secondly, a larger magnification light microscope is required to have higher stability for the inserted tube endoscope. The existing colonoscopy detection equipment is not convenient for supporting and fixing the inspector's anus and fixing the tube, nor is it convenient for inserting the intestinal insertion tube and flexible penetration of the probe body. It is not possible to input water or other inhibitors for interventional comparative screening or detection. Therefore, we proposed a new temperature-controllable, inflatable and expandable new intestinal flora detection device and a screening or detection method based on the device in the intestine to solve the above-mentioned problems. Summary of the invention

[0006] The purpose of the present invention is to provide an intestinal flora detection device to solve the problems raised in the above background technology.

[0007] To achieve the above object, the present invention provides the following technical solutions:

[0008] An intestinal flora detection device includes a probe body, provided with a first connection portion, which is arranged at one end of the probe body;

[0009] A second connecting part is provided, which is arranged at the other end of the first connecting part; a colonoscope insertion tube is provided, which is arranged at the other end of the second connecting part; an expansion cover assembly is provided, which is used to expand and fix the anus of the inspector when the inspector performs a colonoscopy, and is arranged on the outer side wall of the colonoscope insertion tube. The expansion cover assembly is an adjustable expansion structure.

[0010] As a further solution of the present invention: the expansion cover assembly includes a sleeve, which is sleeved on the outside of the colonoscope insertion tube, and one end of the sleeve is rotatably provided with a first expansion cover and a second expansion cover, and the inner walls of the first expansion cover and the second expansion cover are provided with two groups of connecting blocks, and multiple groups of the connecting blocks are provided with a group of hinge blocks, and multiple groups of the hinge blocks are connected to a group of connecting rings, and multiple groups of the connecting rings are provided with a group of lifting sleeves inside, and the inner walls of the multiple groups of lifting sleeves are threaded with a group of adjusting screws, and the other ends of the multiple groups of adjusting screws are respectively connected to the output ends of the two groups of bidirectional rotating parts.

[0011] As a further solution of the present invention: a support sleeve is arranged on the outer side of the second connecting portion, and an inner inflatable balloon is arranged inside the support sleeve.

[0012] As a further solution of the present invention: the support sleeve is made of a deformable material, such as a soft colloid material.

[0013] As a further solution of the present invention: a camera structure is arranged on the probe body.

[0014] As a further solution of the present invention: two groups of heating wires are arranged on the inner wall of the probe body.

[0015] As a further solution of the present invention: a plurality of groups of gas ports are provided on the probe body.

[0016] As a further solution of the present invention: one end of each of the plurality of groups of air ports is provided with a group of air tubes, and each of the plurality of groups of air tubes passes through the first connecting portion, the second connecting portion and the colonoscope insertion tube, and extends to the outside of the colonoscope insertion tube.

[0017] As a further solution of the present invention: a plurality of water outlets are arranged on one side wall of the first connecting portion, and the water outlet is a structure of outlet flushing and reverse outlet blocking water and objects.

[0018] As a further solution of the present invention: a group of water pipes are provided at one end of the multiple groups of water outlets, and the other ends of the multiple groups of water pipes pass through the first connecting part, the second connecting part and the colonoscope insertion tube, and extend to the outside of the colonoscope insertion tube.

[0019] The detection device is also provided with a controller, which is provided with a control center module, a storage module, a camera and video module, a display module, a heating module, an inflation expansion module 1, an inflation module 2, a water injection module, and an inhibitor injection module. The control center is respectively controlled and connected with the storage module, the camera and video module, the display module, the heating module, the inflation expansion module 1, the inflation module 2, the water injection module, and the inhibitor injection module.

[0020] A detection method or troubleshooting method based on the above detection device, characterized in that the method comprises the following:

[0021] S1. When the probe body is inserted into the intestine of the inspected person, the unexpanded first expansion cover and the second expansion cover are inserted into the anus of the inspected person, and then the two sets of two-way rotating parts are twisted, and the two-way rotating parts drive multiple sets of adjusting screws to rotate, and the multiple sets of adjusting screws drive multiple sets of lifting sleeves to move, and the multiple sets of lifting sleeves drive multiple sets of hinge blocks to move through multiple sets of connecting rings, and the multiple sets of hinge blocks thereby drive multiple sets of connecting blocks to move, and the multiple sets of connecting blocks 9 drive the first expansion cover and the second expansion cover to move, so that the first expansion cover and the second expansion cover can expand the anus of the inspected person, and then the probe body is sent into the body of the inspected person through the enteroscope insertion tube, and the anus of the inspected person is expanded and fixed by setting the expansion cover assembly, and the probe body is inserted into the intestine of the inspected person;

[0022] S2. First, check the intestinal flora in the intestine without heating, water injection or inhibitors, and obtain the first intestinal condition data;

[0023] S3. Air is delivered to the inflatable balloon and the air port through multiple groups of tracheas, so that the inner inflatable balloon can expand the support sleeve 15, inflate the intestine, and partially expand and inflate the intestine for inspection, comparison, and acquisition of video data; the trachea and air port of the inflatable balloon are connected to independent tracheas respectively.

[0024] S4. The heating wire of the probe body is heated to adjust the temperature, and the probe body is used to deeply inspect the intestines of the person to adjust different temperatures for comparative testing, and obtain video and local magnification data;

[0025] S5. Use multiple groups of water pipes to inspect and compare the water and inhibitors delivered at the outlet, and obtain video and local magnification data.

[0026] During real-time testing, if abnormalities in the intestinal flora are found in the intestine or a certain part, S3 to S5 are used simultaneously to perform detection, viewing, and comparison, and obtain video and local magnification data. Finally, the intestinal contents of that part are taken out for sequencing analysis and testing.

[0027] In step S2, when the probe body is obstructed, air is delivered to the inflated balloon through multiple groups of air tubes so that the inner inflated balloon can support the support sleeve, thereby flexibly deepening the probe body, or multiple groups of air ports are used to blow the intestines around the probe body at the same time, or both are performed simultaneously, thereby flexibly deepening the probe body.

[0028] Compared with the prior art, the present invention has the following beneficial effects:

[0029] A temperature-controllable, gas-controllable and expandable real-time detection device for intestinal flora and an intestinal flora detection method based on the device are realized. By setting a heating wire, the temperature of the probe body can be adjusted, so that when the probe body penetrates deeply into the intestine of the inspector, different temperatures can be adjusted at any time for detection, and different temperature detection data can be sampled. At the same time, it can be used to reduce the low temperature difference, avoid the discomfort of the inspector caused by the temperature difference stimulation, and improve the comfort of the inspector during the inspection; at the same time, air can be delivered to the inflatable balloon or air port inwardly through multiple groups of air pipes, so that the inflated balloon can expand the support sleeve, so that the intestinal part can be partially expanded and detected or the probe body can be supported for convenient in-depth detection, and the intestinal tract around the probe body can be blown by multiple groups of air ports for blowing intervention detection, which is also convenient for the probe body to be further flexibly penetrated; at the same time, water can be delivered to the water outlet through multiple groups of water pipes, so that the water outlet can clean the intestine or input water or inhibitors for intervention detection;

[0030] When used for detection, the anus of the inspector can be expanded and fixed by setting the expansion cover assembly, so as to facilitate the insertion of the probe body. At the same time, the support sleeve, the inner inflatable balloon, the air port and the air tube can be provided to support the inside of the inspector's intestine, so that the probe body can be more flexibly inspected inside the inspector's intestine. The overall realization can be achieved by a multifunctional device.

[0031] The device-based intestinal flora detection method or screening method is simple, rapid and effective, and improves the accuracy of detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 It is a structural schematic diagram of the present invention.

[0033] Figure 2 It is a structural schematic diagram of the probe body in the present invention.

[0034] Figure 3 for Figure 2 A is a schematic diagram of the enlarged structure.

[0035] Figure 4 It is a schematic diagram of the structure of the heating wire in the present invention.

[0036] Figure 5 It is a schematic diagram of the structure of the expansion cover assembly in the present invention.

[0037] Figure 6 for Figure 5 B is a schematic diagram of the enlarged structure.

[0038] Figure 7 1 is a structural diagram of a control module of the device of the present invention.

[0039] Among them: 1. Probe body; 2. First connecting part; 3. Second connecting part; 4. Colonoscope insertion tube; 5. Expansion cover assembly; 6. Sleeve; 7. First expansion cover; 8. Second expansion cover; 9. Connecting block; 10. Articulated block; 11. Connecting ring; 12. Lifting sleeve; 13. Adjusting screw; 14. Bidirectional rotating part; 15. Support sleeve; 16. Inflatable balloon; 17. Camera structure; 18. Heating wire; 19. Air port; 20. Air pipe; 21. Water outlet; 22. Water pipe. DETAILED DESCRIPTION

[0040] In one embodiment, Figure 1-Figure 6 As shown, a device for detecting intestinal flora comprises:

[0041] Probe body 1;

[0042] A first connecting portion 2, which is arranged at one end of the probe body 1;

[0043] A second connecting portion 3, which is arranged at the other end of the first connecting portion 2;

[0044] A colonoscope insertion tube 4, which is arranged at the other end of the second connecting portion 3;

[0045] The expansion cover assembly 5 is used to expand and fix the anus of the examiner when the examiner is doing colonoscopy, and is arranged on the outer side wall of the colonoscope insertion tube 4. The expansion cover assembly 5 is an adjustable expansion structure;

[0046] The expansion cover assembly 5 includes a sleeve 6, which is sleeved on the outside of the enteroscope insertion tube 4. One end of the sleeve 6 is rotatably provided with a first expansion cover 7 and a second expansion cover 8. Two groups of connecting blocks 9 are provided on the inner walls of the first expansion cover 7 and the second expansion cover 8. Multiple groups of connecting blocks 9 are provided with a group of hinge blocks 10. Multiple groups of hinge blocks 10 are connected with a group of connecting rings 11. Multiple groups of connecting rings 11 are provided with a group of lifting sleeves 12 inside. Multiple groups of lifting sleeves 12 are threadedly provided with a group of adjusting screws 13 on the inner walls. The other ends of the multiple groups of adjusting screws 13 are respectively connected to the output ends of the two groups of bidirectional rotating members 14.

[0047] Specifically, when in use, the unexpanded first expansion cover 7 and the second expansion cover 8 are inserted into the anus of the inspector, and then the two sets of two-way rotating parts 14 are twisted, the two-way rotating parts 14 drive multiple sets of adjusting screws 13 to rotate, and the multiple sets of adjusting screws 13 drive multiple sets of lifting sleeves 12 to move, and the multiple sets of lifting sleeves 12 drive multiple sets of hinge blocks 10 to move through multiple sets of connecting rings 11, and the multiple sets of hinge blocks 10 thereby drive multiple sets of connecting blocks 9 to move, and the multiple sets of connecting blocks 9 drive the first expansion cover 7 and the second expansion cover 8 to move, so that the first expansion cover 7 and the second expansion cover 8 can expand the anus of the inspector, and then the probe body 1 is sent into the body of the inspector through the colonoscope insertion tube 4; by setting the expansion cover assembly 5, the anus of the inspector can be expanded and fixed, which facilitates the deepening of the colonoscope insertion tube 4, thereby facilitating the probe body 1 to flexibly penetrate into the intestine of the inspector, and facilitating the probe body 1 to inspect the intestine of the inspector.

[0048] like Figure 1-Figure 4As shown, a support sleeve 15 is provided on the outside of the second connection part 3, and an inner inflatable balloon 16 is provided inside the support sleeve 15; the support sleeve 15 is made of a deformable material; a plurality of groups of air ports 19 are provided on the probe body 1; a group of tracheas 20 are provided at one end of the plurality of groups of air ports 19, and the plurality of groups of tracheas 20 pass through the first connection part 2, the second connection part 3 and the colonoscope insertion tube 4, and extend to the outside of the colonoscope insertion tube 4, and the trachea of ​​the inflatable balloon 16 and the trachea of ​​the air port 19 are connected to each other independently; when the probe body 1 is obstructed, the balloon 16 or the air port can be inflated inwardly through the plurality of tracheas. 19 is used to supply air, so that the inner inflatable balloon 16 can expand the support sleeve 15, thereby expanding the inside of the intestine, and the multiple groups of air ports 19 blow the intestine around the probe body 1, thereby facilitating the flexible and in-depth penetration of the probe body 1; by setting the support sleeve 15, the inner inflatable balloon 16, the air ports 19 and the trachea 20, it is convenient to support the inside of the intestine of the inspector, thereby facilitating the probe body 1 to more flexibly inspect the inside of the intestine of the inspector, and at the same time, it is possible to partially expand the inside of the intestine, and perform inspection, comparison and detection of air intervention.

[0049] like Figure 1-Figure 7 As shown, a camera structure 17 is provided on the probe body 1; the camera structure 17 is provided to facilitate viewing the inside of the intestine of the inspector. Two groups of heating wires 18 are provided on the inner wall of the probe body 1; the heating wires 18 facilitate the temperature adjustment of the probe body 1, so as to reduce the temperature difference when the probe body 1 goes deep into the inside of the intestine of the inspector, avoid the temperature difference stimulation from bringing psychological pressure to the inspector, and realize the detection and viewing of different temperature interventions. A plurality of water outlets 21 are provided on one side wall of the first connecting part 2; a group of water pipes 22 are provided at one end of the plurality of water outlets 21, and the other ends of the plurality of water pipes 22 pass through the first connecting part 2, the second connecting part 3 and the colonoscope insertion tube 4, and extend to the outside of the colonoscope insertion tube 4; the plurality of water pipes 22 can transport water to the water outlet 21, so that the water outlet 21 can clean the inside of the intestine, thereby improving the observation effect of the camera structure 17, and at the same time, it can realize the detection, comparison and comparison of input water or inhibitors or other interventions, which is practical. The camera structure 17 is a commonly used structure that can magnify microscopy, take pictures, record videos, and illuminate. It is an existing camera structure 17 with comprehensive functions.

[0050] The above embodiment discloses an intestinal flora detection device. When in use, the unexpanded first expansion cover 7 and the second expansion cover 8 are inserted into the anus of the inspector, and then the two sets of two-way rotating parts 14 are twisted, and the two-way rotating parts 14 drive the multiple sets of adjusting screws 13 to rotate, and the multiple sets of adjusting screws 13 drive the multiple sets of lifting sleeves 12 to move, and the multiple sets of lifting sleeves 12 drive the multiple sets of hinge blocks 10 to move through the multiple sets of connecting rings 11, and the multiple sets of hinge blocks 10 thereby drive the multiple sets of connecting blocks 9 to move, and the multiple sets of connecting blocks 9 drive the first expansion cover 7 and the second expansion cover 8 to move, so that the first expansion cover 7 and the second expansion cover 8 can expand the anus of the inspector, and then the probe is inserted through the colonoscope insertion tube 4. The probe body 1 is inserted into the body of the inspected person, and the temperature of the probe body 1 can be adjusted for detection through the heating wire 18; at the same time, when the probe body 1 is obstructed, air can be sent to the inflated balloon 16 through the trachea, so that the inner inflated balloon 16 can support the support sleeve 15, or the air port 19 can be used to blow the intestinal space around the probe body 1, so as to facilitate the flexible penetration of the probe body 1, or the air port 19 can be used to move objects near the probe for easy viewing; at the same time, water can be transported to the water outlet 21 through multiple groups of water pipes 22, so that the water outlet 21 can clean the inside of the intestine, thereby improving the observation effect and intervention detection of the camera structure 17, which is relatively practical. The air pipe connected to the inflatable balloon 16 is provided with an inflation expansion valve and an air pump control connection, the air pipe connected to the air port 19 is provided with an inflation valve and an air pump connection, one end of the air pipe is connected to the water outlet, and the other end is provided with a double-mouth pipe, the double-mouth pipe is respectively provided with a water injection valve and an inhibitor injection valve, and is respectively connected to the water source pipe and the inhibitor pipe. The inflation expansion valve, air pump, inflation valve, double-mouth pipe, water injection valve, inhibitor injection valve, water source pipe and inhibitor pipe belong to existing structural products and can also be externally connected components. They are not detailed here. During operation, the gas supply, water injection and inhibitor injection in the intestine are all accepted by the intestine and used in trace amounts.

[0051] The detection device is also provided with a controller, and the controller is provided with a control center module, a storage module, a camera and video module, a display module, a heating module, an inflation expansion module 1, an inflation module 2, a water injection module, and an inhibitor injection module. The control center is respectively connected to the storage module, the camera and video module, the display module, the heating module, the inflation expansion module 1, the inflation module 2, the water injection module, and the inhibitor injection module. The camera and video module, the heating module, the inflation expansion module 1, the inflation module 2, the water injection module, and the inhibitor injection module are respectively connected to the above-mentioned camera mechanism 17, the heating wire 18, the external inflation expansion valve connected to the air pipe of the inflatable balloon 16, the inflation valve connected to the air pipe connected to the air port 19, the water injection valve, and the inhibitor injection valve to realize the control operation of the electronic parts. The device can be connected to an external computer to transmit data to realize data storage, real-time control operation and detection comparison. The electronic circuit connection structure of the device belongs to the prior art and does not belong to the scope of innovation, so it is not detailed here.

[0052] The above device can also be used for local cleaning or other inspections, and is an intestinal cleaning device or an intestinal detection device.

[0053] A detection method or troubleshooting method based on the above detection device, characterized in that the method comprises the following:

[0054] S1. The device control center stores the routine intestinal data of healthy people's intestinal flora, and can also be connected to an external computer with stored data.

[0055] When the probe body 1 is inserted into the intestine of the inspected person, the unexpanded first expansion cover 7 and the second expansion cover 8 are inserted into the anus of the inspected person, and then the two sets of two-way rotating parts 14 are twisted, and the two-way rotating parts 14 drive the multiple sets of adjusting screws 13 to rotate, and the multiple sets of adjusting screws 13 drive the multiple sets of lifting sleeves 12 to move, and the multiple sets of lifting sleeves 12 drive the multiple sets of hinge blocks 10 to move through the multiple sets of connecting rings 11, and the multiple sets of hinge blocks 10 thereby drive the multiple sets of connecting blocks 9 to move, and the multiple sets of connecting blocks 9 drive the first expansion cover 7 and the second expansion cover 8 to move, so that the first expansion cover 7 and the second expansion cover 8 can expand the anus of the inspected person, and then the probe body 1 is sent into the body of the inspected person through the enteroscope insertion tube 4, and the anus of the inspected person is expanded and fixed by setting the expansion cover assembly 5, and the probe body 1 is inserted into the intestine of the inspected person;

[0056] S2. First, magnify and inspect the intestine without heating, water injection or inhibitors, and obtain the first intestinal data;

[0057] When the probe body 1 is obstructed, multiple groups of air tubes 20 are used to deliver air to the inflated balloon 16 so that the inflated balloon 16 can support the support sleeve 15, which is convenient for the probe body 1 to be flexibly penetrated, or multiple groups of air ports 19 are used to blow air to the intestines around the probe body 1, or both are performed simultaneously, so as to facilitate the probe body 1 to be flexibly penetrated;

[0058] S3. The inflatable balloon 16 and the air port 19 are supplied with air through the multiple trachea 20, so that the inflatable balloon 16 can expand the support sleeve 15, inflate the intestine, and partially expand and inflate the intestine to detect and obtain video data;

[0059] S4. The heating wire of the probe body is heated to adjust the temperature, and the probe body is used to deeply inspect the intestines of the person to adjust different temperatures for detection, and obtain video data;

[0060] S5. Through multiple groups of water pipes 22, the water outlet 21 is transported to detect the inhibitor and obtain video data;

[0061] During real-time detection, if an abnormality is found in the intestinal flora of a certain part of the intestine, the operations of S3 to S5 are used to simultaneously detect and view, obtain video data, and perform the following temperature difference repeatability test twice:

[0062] Heating and expansion at 38°C, inputting water or inhibitors for detection and comparison;

[0063] Heating and expansion at 39°C, inputting water or inhibitors for detection and comparison;

[0064] Heating and expansion at 40℃, inputting water or inhibitor for testing and comparison;

[0065] The data of the previous S2, S3, S4, S5, repeated S3-S5 operations and temperature difference repeatability tests are compared and stored. Finally, based on the test data, the intestinal content that needs to be tested most is determined to be taken out, so as to predict intestinal flora abnormalities or problem areas. The intestinal contents are used for sequencing analysis and detection, and further specific classification of the intestinal flora is performed. The intestinal contents can be taken out by using other existing structures, which will not be detailed here.

[0066] Through experiments, it was found that the accuracy of intestinal flora was increased by 80% by using conventional testing to directly take intestinal contents for sequencing analysis (high-throughput sequencing analysis or fluorescent quantitative PCR analysis or other detection analysis) compared with taking intestinal contents for high-throughput sequencing analysis or fluorescent quantitative PCR analysis or other detection analysis after the above-mentioned test. This is very effective and practical.

[0067] The above-mentioned method of use is also a method for selective sampling of intestinal flora in different intestinal tracts under different temperature states, different segments, and different expansion states.

[0068] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A device for detecting intestinal flora, characterized in that: The invention comprises a probe body (1), a first connection part (2) arranged at one end of the probe body (1), a second connection part (3) arranged at the other end of the first connection part (2), a colonoscope insertion tube (4) arranged at the other end of the second connection part (3), and an expansion cover assembly (5) used for expanding and fixing the anus of the examiner when the examiner performs colonoscopy, and arranged on the outer side wall of the colonoscope insertion tube (4). The expansion cover assembly (5) is an adjustable expansion structure.

2. The intestinal flora detection device according to claim 1, characterized in that: The expansion cover assembly (5) comprises a sleeve (6), wherein the sleeve (6) is sleeved on the outer side of the colonoscope insertion tube (4), and a first expansion cover (7) and a second expansion cover (8) are rotatably provided on one end of the sleeve (6), and two groups of connecting blocks (9) are provided on the inner walls of the first expansion cover (7) and the second expansion cover (8), and a plurality of groups of connecting blocks (9) are provided with a group of hinge blocks (10), and a plurality of groups of hinge blocks (10) are connected with a group of connecting rings (11), and a group of lifting sleeves (12) are provided inside the plurality of groups of connecting rings (11), and a group of adjusting screws (13) are threadedly provided on the inner walls of the plurality of groups of lifting sleeves (12), and the other ends of the plurality of groups of adjusting screws (13) are respectively connected to the output ends of the two groups of bidirectional rotating members (14).

3. The intestinal flora detection device according to claim 1, characterized in that: A support sleeve (15) is arranged on the outer side of the second connecting portion (3), an inner inflatable balloon (16) is arranged inside the support sleeve (15), and the support sleeve (15) is made of a deformable material.

4. The intestinal flora detection device according to claim 1, characterized in that: The probe body (1) is provided with a camera structure (17), and the inner wall of the probe body (1) is provided with two groups of heating wires (18).

5. The intestinal flora detection device according to claim 1, characterized in that: The probe body (1) is provided with a plurality of groups of air ports (19), one end of each of the plurality of groups of air ports (19) is provided with a group of air tubes (20), and each of the plurality of groups of air tubes (20) passes through the first connecting portion (2), the second connecting portion (3) and the colonoscope insertion tube (4), and extends to the outside of the colonoscope insertion tube (4).

6. The intestinal flora detection device according to claim 1, characterized in that: A plurality of water outlets (21) are arranged on a side wall of the first connecting portion (2), one end of each of the plurality of water outlets (21) is provided with a group of water pipes (22), and the other ends of each of the plurality of water pipes (22) pass through the first connecting portion (2), the second connecting portion (3) and the colonoscope insertion tube (4), and extend to the outside of the colonoscope insertion tube (4).

7. The intestinal flora detection device according to claim 1, characterized in that: The detection device is also provided with a controller, which is provided with a control center module, a storage module, a camera and video module, a display module, a heating module, an inflation expansion module 1, an inflation module 2, a water injection module, and an inhibitor injection module. The control center is respectively controlled and connected with the storage module, the camera and video module, the display module, the heating module, the inflation expansion module 1, the inflation module 2, the water injection module, and the inhibitor injection module.

8. A detection method based on the intestinal flora detection device according to any one of claims 1 to 7, characterized in that: The method comprises the following: S1. When the probe body (1) is inserted into the intestine of the inspected person, the unexpanded first expansion cover (7) and the second expansion cover (8) are inserted into the anus of the inspected person, and then the two sets of bidirectional rotating parts (14) are twisted, and the bidirectional rotating parts (14) drive the multiple sets of adjusting screws (13) to rotate, and the multiple sets of adjusting screws (13) drive the multiple sets of lifting sleeves (12) to move, and the multiple sets of lifting sleeves (12) drive the multiple sets of hinge blocks (10) to move through the multiple sets of connecting rings (11), and the multiple sets of hinge blocks (10) thereby drive the multiple sets of connecting blocks (9) to move, and the multiple sets of connecting blocks (9) drive the first expansion cover (7) and the second expansion cover (8) to move, so that the first expansion cover (7) and the second expansion cover (8) can expand the anus of the inspected person, and then the probe body (1) is sent into the body of the inspected person through the enteroscope insertion tube (4), and the anus of the inspected person is expanded and fixed by setting the expansion cover assembly 5, and the probe body (1) is inserted into the intestine of the inspected person; S2. First, magnify and inspect the intestine without heating, water injection or inhibitors, and obtain the first intestinal data; S3. Air is delivered to the inflatable balloon (16) and the air port (19) through multiple groups of trachea (20), so that the inflatable balloon (16) expands the support sleeve (15), inflates the intestine, and performs partial expansion and inflation comparison detection on the inside of the intestine and obtains video and local magnification data; S4. The heating wire of the probe body is heated to adjust the temperature, and the probe body is used to deeply inspect the intestines of the person to adjust different temperatures for comparative testing, and obtain video and local magnification data; S5. Comparative detection of water and inhibitors delivered to the water outlet 21 is performed through multiple groups of water pipes 22, and video and local magnification data are obtained.

9. A detection method based on an intestinal flora detection device according to claim 8, characterized in that: During real-time detection, when an abnormality is found in a certain part of the intestine, steps S3 to S5 are used to perform re-testing and viewing at the same time, and video data is obtained. Finally, the intestinal contents of that part are taken out for sequencing analysis and detection.

10. A detection method based on an intestinal flora detection device according to claim 8, characterized in that: In step S2, when the probe body (1) is obstructed, air is delivered to the inflated balloon (16) through multiple groups of air tubes (20), so that the inflated balloon (16) can support the support sleeve (15), thereby facilitating the flexible penetration of the probe body (1), or multiple groups of air ports (19) blow air to the intestines around the probe body (1), or both are performed simultaneously, thereby facilitating the flexible penetration of the probe body (1).

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