An automatic blood sample testing device

Through the combined design of magnetic separation assembly and mixing assembly, the problem of long mixing cycle in the prior art is solved, and the rapid mixing of the reaction cup liquid is achieved, and the detection efficiency and reliability of the device are improved.

CN119643848BActive Publication Date: 2025-07-29NINGBO AUCHEER BIOTECHNOLOGY CO LTD

Patent Information

Application Number
CN202510188625.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-02-20
Publication Date
2025-07-29
Estimated Expiration
2045-02-20

AI Technical Summary

Technical Problem

In the prior art, the solution in the reactor is mixed by a mixing mechanism and a stirring rod. The mixing operation is performed for a long period of time, which affects the detection efficiency.

Method used

The combination design of magnetic separation components, waste liquid discharge components and mixing components is adopted. The magnetic separation components are used to adsorb magnetic particles in the reaction cup, and then clean the waste liquid discharge components and shake it with the bottom of the reaction cup for contact and shaking, shortening the mixing cycle.

Benefits of technology

The mixing time of liquid in the reaction cup is shortened, the detection efficiency is improved, and the reaction cup is prevented from rupturing and improper mixing of liquid.

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Abstract

The present application discloses an automatic blood sample testing device, which relates to the technical field of blood sample detection. The device includes a fixing frame, on which a magnetic separation assembly is provided, and a reaction cup is placed on the magnetic separation assembly. A waste liquid discharge assembly is provided above the magnetic separation assembly on the fixing frame, and the waste liquid discharge assembly corresponds to the reaction cup placed on the magnetic separation assembly. Mixing assemblies are provided on both sides of the fixing frame at the positions of the magnetic separation assembly, and the mixing assemblies are in contact with the bottom of the reaction cup. The magnetic separation assembly adsorbs the magnetic particles combined with the antigen in the blood sample in the reaction cup, adds a cleaning solution to the reaction cup for cleaning, discharges the waste liquid after cleaning in the reaction cup through the waste liquid discharge assembly, then adds an acid to the reaction cup for reaction, and the mixing assemblies are in contact with the bottom of the reaction cup to shake the reaction cup in time, so as to mix the liquid in the reaction cup and shorten the mixing time of the mixing assemblies.
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Description

Technical Field

[0001] This application relates to the technical field of blood sample detection, and in particular to an automatic blood sample testing device. Background Art

[0002] In chemiluminescence immunoassay, the magnetic particle complex is a carrier of the signal to be measured. Magnetic separation technology is to perform solid-liquid phase separation on the reaction solution after mixing the magnetic particle complex with the blood sample and the reaction reagent. In order to ensure the effect of magnetic separation, during the separation process, the reaction solution needs to be fully mixed. Thus, accurate test results can be obtained. In the current existing technologies, mainly contact-type paddle mixing and suction and liquid injection mixing structures are used. In an automatic detection device, usually one mixing mechanism and one stirring rod are adopted to stir the solution in one reactor at a time to mix the liquid in the reactor.

[0003] Regarding the above related technologies, the inventor believes that by using one mixing mechanism and one stirring rod to mix the solution in the reactor, the mixing action execution period of the mixing mechanism is relatively long. Summary of the Invention

[0004] The purpose of this application is to provide an automatic blood sample testing device to improve the problem that the mixing action execution period of the mixing mechanism is relatively long when using one mixing mechanism and one stirring rod to mix the solution in the reactor.

[0005] An automatic blood sample testing device provided by this application adopts the following technical solutions:

[0006] An automatic blood sample testing device includes a fixing frame. Above the fixing frame, there is a magnetic separation assembly for placing reaction cups. Above the magnetic separation assembly, there is a waste liquid discharge assembly corresponding to the reaction cups. On both sides of the fixing frame where the magnetic separation assembly is located, there are mixing assemblies that are in contact with the bottom of the reaction cups.

[0007] By adopting the above technical solutions, the reaction cup is placed into the magnetic separation assembly. The magnetic particles combined with the antigen in the blood sample in the reaction cup are adsorbed by the magnetic separation assembly. Cleaning liquid is added to the reaction cup for cleaning. The waste liquid after cleaning in the reaction cup is discharged through the waste liquid discharge assembly located above the magnetic separation assembly. Then, acid is added to the reaction cup for reaction. By making the mixing assemblies arranged on both sides of the magnetic separation assembly contact the bottom of the reaction cup, the reaction cup starts to be shaken to fully mix the liquid in the reaction cup, shortening the mixing period for mixing the reaction cup and shortening the reaction time of the liquid in the reaction cup.

[0008] Optionally, the magnetic separation assembly includes a fixed seat disposed above the fixed frame. The fixed seat is provided with a fixing hole, and a rotating rod is rotatably disposed in the fixing hole. A rotating disk is fixedly connected above the fixed seat on the rotating rod. A first driving member belt-drivenly connected to the rotating rod is connected and disposed below the fixed frame. A first fixing groove corresponding to the reaction cup is formed at the edge of the rotating disk. The first fixing groove is in contact with the edge position of the reaction cup, and a chamfer is formed on one side of the first fixing groove close to the fixed frame.

[0009] By adopting the above technical solution, a fixed seat is installed on the fixed frame, a fixing hole is formed at the central position of the fixed seat, the rotating rod is rotatably disposed in the fixing hole, a first driving member belt-drivenly connected to the rotating rod is connected and disposed on the fixed frame, the rotating disk is fixedly connected to the rotating rod above the fixed seat, and the rotating disk is driven to rotate by driving the rotating rod through the first driving member; a first fixing groove is formed on the rotating disk, and a chamfer is formed on one side of the first fixing groove close to the fixed seat, so that the reaction cup placed in the first fixing groove can shake under the action of the mixing assembly, preventing the reaction cup from having too large a contact area with the side wall of the first fixing groove when the mixing assembly shakes the reaction cup and causing the reaction cup to break.

[0010] Optionally, a first support frame is connected and disposed above the fixed frame on the fixed seat. The first support frame is located on one side of the waste liquid discharge assembly close to the rotating disk. One end of the first support frame is provided with a cleaning liquid adding hole corresponding to the reaction cup, and the other end of the first support frame is provided with an acid adding hole corresponding to the reaction cup. The acid adding hole and the cleaning liquid adding hole are on the same axis as the mixing assembly.

[0011] By adopting the above technical solution, a first support frame is connected and disposed on the fixed frame, so that the first support frame is located above the rotating disk and corresponds to the waste liquid discharge assembly. A cleaning liquid adding hole is provided at one end of the first support frame. When the reaction cup rotates with the rotating disk and is located at the same axis position as the cleaning liquid adding hole, cleaning liquid is added to the reaction cup, and the mixing assembly on the fixed frame starts to shake the reaction cup to mix the liquid in the reaction cup; an acid adding hole is provided at the other end of the first support frame, acid is added to the reaction cup, and the mixing assembly shakes the reaction cup after adding acid, shortening the mixing period of the mixing assembly and fully mixing the liquid in the reaction cup.

[0012] Optionally, a connecting groove is formed in the side wall of the fixed seat, and a magnetic member for adsorbing the antigen combined with the magnetic particles in the reaction cup is connected and disposed in the connecting groove. A groove corresponding to the mixing assembly is formed in the side wall of the fixed seat.

[0013] By adopting the above technical solution, a magnetic member is installed in the connecting groove provided on the fixing seat. When the reaction cup on the rotating disk rotates with the rotating disk, the magnetic member adsorbs the magnetic particles in the reaction cup that are magnetically connected to the antigens in the blood sample. This prevents the waste liquid in the reaction cup from being discharged together with the antigens in the reaction cup when cleaning liquid is subsequently added to the reaction cup for cleaning, thereby preventing the waste liquid in the reaction cup from being discharged together with the antigens in the reaction cup when it is drawn out by the waste liquid discharge component, causing errors in subsequent test results.

[0014] Optionally, the waste liquid discharge assembly includes a waste liquid needle, the fixed frame is connected to an upwardly extending mounting frame, the mounting frame is slidably connected to a connecting frame, the connecting frame is in contact with the mixing assembly, a support frame 2 is connected above the connecting frame, the support frame 2 is located above the support frame 1 and is connected to the waste liquid needle, and a driving member 2 is connected below the fixed frame, the driving rod of the driving member 2 is fixedly connected to a screw rod, and the screw rod is rotatably connected to the connecting frame.

[0015] By adopting the above technical solution, the upwardly extending mounting frame is connected to the fixed frame, the connecting frame is slidably connected to the mounting frame, the connecting screw is rotated on the connecting frame, the driving member 2 is connected to the fixed frame, the driving rod of the driving member 2 is fixedly connected to the screw, and the screw is driven by the driving member 2 to rotate, so that the screw pushes the connecting frame to move on the mounting frame, so that the connecting frame drives the mixing assembly to move and contact the bottom of the reaction cup; the supporting frame 2 is connected to the connecting frame, and the waste liquid needle is connected to the supporting frame 2, so that the waste liquid needle moves toward the reaction cup as the connecting frame moves, and the waste liquid generated after the cleaning liquid is added to the reaction cup is extracted.

[0016] Optionally, a fixed block is connected to one side of support frame 1 close to support frame 2, and the fixed block and support frame 1 are provided with interconnected positioning grooves. The end of the waste liquid needle away from support frame 1 is located in the positioning groove and is on the same axis as the reaction cup placed on the rotating disk.

[0017] By adopting the above technical solution, a fixed block is connected to the support frame one, and interconnected positioning grooves are provided on the fixed block and the support frame one to support the end of the waste liquid needle away from the support frame two, thereby preventing the end of the waste liquid needle from shaking too much when the driving member two drives the connecting frame to move and drives the waste liquid needle close to the reaction cup, thereby preventing the waste liquid in the reaction cup from being discharged due to the excessive deviation from the reaction cup.

[0018] Optionally, an elastic member 1 is connected between the side of the support frame 2 close to the rotating disk and the waste liquid needle, and the elastic member 1 abuts against the fixed block when the driving member 2 drives the waste liquid needle to move toward the reaction cup.

[0019] By adopting the above technical solution, an elastic member I is connected and arranged between one side of the second support frame close to the rotating disc and the waste liquid needle. When the driving member II drives the connecting frame to move towards the fixed frame and the waste liquid needle moves towards the reaction cup, the elastic member I abuts against the fixed block on the first support frame, and the elastic member I contracts, playing a certain buffering role in the waste liquid needle entering the reaction cup, reducing the possibility of the waste liquid needle colliding with the bottom of the reaction cup. At the same time, when the driving member II drives the connecting frame away from the fixed frame, the elastic member I slowly resets, pushing the waste liquid needle to still stay in the reaction cup for a period of time, reducing the possibility of waste liquid residue in the reaction cup.

[0020] Optionally, the mixing assembly includes cams arranged on both sides of the fixed frame. An installation plate is arranged above the fixed frame and overlaps with the connecting frame. The cams are rotatably arranged above the installation plate. A driving member III for driving the cams to rotate is connected and arranged below the installation plate. A fixing groove II in contact with the reaction cup is opened above the cams, and the fixing groove II is arranged deviating from the rotation center of the cams.

[0021] By adopting the above technical solution, an installation plate overlapping with the connecting frame is arranged on the fixed frame, and cams are rotatably connected to the installation plate. The driving member II drives the connecting frame to move on the installation frame to drive the installation plate to move, so that the cams move at positions corresponding to the grooves opened on the fixed seat, preventing the cams from colliding with the fixed seat when moving up and down; a fixing groove II in contact with the reaction cup is opened at a position deviating from the rotation center of the cams, and the fixing groove II on the cams contacts the bottom of the reaction cup as the installation plate moves; a driving member III is connected and arranged on the installation plate, and the driving member III drives the cams to rotate, so that the fixing groove II on the cams drives the reaction cup to rotate around the rotation center of the cams, shaking the reaction cup and mixing the liquid in the reaction cup.

[0022] Optionally, one end of the installation plate close to the connecting frame is connected with a connecting plate I, and both sides of the connecting frame are connected with connecting plates II in contact with the connecting plate I. One ends of the connecting plate I and the connecting plate II close to each other are bent, and the bent part of the connecting plate I is located above the bent part of the connecting plate II and overlaps with the connecting plate II.

[0023] By adopting the above technical solution, a connecting plate I is connected and arranged at one end of the installation plate close to the connecting frame, and a connecting plate II is connected and arranged on the connecting frame. The bent part of the connecting plate I is located above the bent part of the connecting plate II and overlaps with the connecting plate II, enabling the installation plate to move upward with the connecting frame, driving the cams close to the reaction cup, preventing the reaction cup from being unable to contact the cams and affecting the mixing of the liquid in the reaction cup.

[0024] Optionally, the mounting plate and the side wall of the fixing bracket are both connected with protruding members, and an elastic member II is arranged between the protruding members. The elastic member II pulls the mounting plate to move towards the position close to the fixing bracket. The fixing bracket is provided with a communication groove adapted to the driving member III fixed to the mounting plate. The mounting plate is provided with a positioning hole, and a positioning rod connected to the fixing bracket is inserted into the positioning hole.

[0025] By adopting the above technical solution, protruding members are connected to the side walls of the mounting plate and the fixing bracket, and an elastic member II is arranged between the protruding members. When the connecting bracket moves towards the fixing bracket under the drive of the driving member II, the elastic member II contracts and pulls the mounting plate close to the fixing bracket, so that the cam is away from the reaction cup, enabling the reaction cup to continue to rotate with the rotating disk; through the positioning hole opened on the mounting plate and the positioning rod inserted into the positioning hole and connected to the fixing bracket, the mounting plate is positioned to prevent the mounting plate from shifting during the up-and-down movement, causing the cam and the reaction cup to be misaligned and the liquid in the reaction cup to be poorly mixed; a communication groove adapted to the driving member III is opened on the fixing bracket to prevent the driving member III from colliding with the fixing bracket when the mounting plate moves downward, affecting the operation of the device.

[0026] In summary, the present application includes at least one of the following beneficial technical effects:

[0027] 1. A fixing seat is installed on the fixing bracket, a fixing hole is opened at the center position of the fixing seat, the rotating rod is rotatably arranged in the fixing hole, a driving member I connected to the rotating rod by belt drive is connected to the fixing bracket, the rotating disk is fixedly connected to the rotating rod above the fixing seat, and the driving member I drives the rotating rod to drive the rotating disk to rotate; a fixing groove I is opened on the rotating disk, and a chamfer is opened on one side of the fixing groove I close to the fixing seat, so that the reaction cup placed in the fixing groove I can be shaken under the action of the mixing assembly, preventing the contact area between the reaction cup and the side wall of the fixing groove I from being too large when the mixing assembly shakes the reaction cup, causing the reaction cup to break;

[0028] 2. A mounting plate overlapping with the connecting bracket is arranged on the fixing bracket, a cam is rotatably connected to the mounting plate, the driving member II drives the connecting bracket to move on the mounting bracket to drive the mounting plate to move, so that the cam moves at a position corresponding to the groove opened on the fixing seat, preventing the cam from colliding with the fixing seat when moving up and down; a fixing groove II in contact with the reaction cup is opened at a position where the cam deviates from the rotation center, and the cam moves with the mounting plate to make the fixing groove II contact the bottom of the reaction cup; a driving member III is connected to the mounting plate, and the driving member III drives the cam to rotate, so that the fixing groove II on the cam drives the reaction cup to rotate around the rotation center of the cam, shaking the reaction cup and mixing the liquid in the reaction cup;

[0029] 3. A convex member is connected to the side walls of the mounting plate and the fixing frame, and an elastic member II is arranged between the convex members. When the connecting frame moves towards the fixing frame under the drive of the drive member II, the elastic member II contracts and pulls the mounting plate closer to the fixing frame, causing the cam to move away from the reaction cup, enabling the reaction cup to continue to rotate with the rotating disk; the mounting plate is positioned through the positioning holes formed in the mounting plate and the positioning rods inserted into the positioning holes and connected to the fixing frame, preventing the mounting plate from shifting during up and down movement, resulting in misalignment between the cam and the reaction cup and improper mixing of the liquid in the reaction cup. Description of the Drawings

[0030] Figure 1 is an overall schematic diagram of an automatic blood sample testing device in the embodiment;

[0031] Figure 2 is Figure 1 a partial enlarged view of A in

[0032] Figure 3 is Figure 1 a partial schematic diagram of B in

[0033] Figure 4 is a cross-sectional schematic diagram of the mixing component and the magnetic separation component of the blood sample testing device.

[0034] In the figure, 1, fixing frame; 12, support frame I; 121, fixing block; 122, positioning groove; 123, cleaning liquid adding hole; 124, acid adding hole; 13, mounting frame; 14, communication groove; 2, magnetic separation component; 21, fixing seat; 211, fixing hole; 212, connecting groove; 213, groove; 22, rotating rod; 23, rotating disk; 231, fixing groove I; 24, drive component I; 25, magnetic part; 3, reaction cup; 4, waste liquid discharging component; 41, waste liquid needle; 411, elastic member I; 42, connecting frame; 421, connecting plate II; 43, support frame II; 44, drive component II; 45, lead screw; 5, mixing component; 51, cam; 511, fixing groove II; 52, mounting plate; 521, connecting plate I; 522, convex member; 523, elastic member II; 524, positioning hole; 53, drive component III; 54, positioning rod. Detailed Embodiment

[0035] The following will Figure 1 - be described Figure 4 in further detail with reference to the attached drawings

[0036] An automatic blood sample testing device, referring to Figure 1 and Figure 4, including a fixing frame 1. On the fixing frame 1, the metal fixing seat 21 in the magnetic separation assembly 2 is connected and fixed to the fixing frame 1 with bolts. A fixing hole 211 is opened at the center position of the fixing seat 21, and the rotating rod 22 is rotatably connected in the fixing hole 211 through a bearing and a bushing. On the side of the fixing frame 1 away from the fixing seat 21, a first driving member 24 is fixedly connected with bolts. The first driving member 24 is a stepping motor connected to a power source. The driving rod of the first driving member 24 is connected to the rotating rod 22 through a pulley and a belt. At one end of the rotating rod 22 above the fixing seat 21, a rotating disc 23 is fixedly connected with bolts. The first driving member 24 drives the rotating rod 22 to rotate, driving the rotating disc 23 to rotate step by step.

[0037] Refer to Figure 1 and Figure 3 , on the fixing frame 1, an upward-extending mounting frame 13 is fixedly connected with bolts. On the mounting frame 13, a connecting frame 42 is slidably connected through a guide rail and a slider. On the connecting frame 42, a lead screw 45 is rotationally connected through a thread. On the fixing frame 1, a second driving member 44 is fixedly connected with bolts. The second driving member 44 is a driving motor connected to a power source. The driving rod of the second driving member 44 is fixedly connected to the lead screw 45 through a coupling. By driving the lead screw 45 to rotate by the second driving member 44, the connecting frame 42 is pushed to move on the mounting frame 13; on the connecting frame 42, a second support frame 43 is fixedly connected with bolts. On the second support frame 43, a waste liquid needle 41 is clamped, so that the connecting frame 42 drives the waste liquid needle 41 to move towards the direction close to the rotating disc 23; on the fixing frame 1, a first support frame 12 is fixedly connected through a metal vertical rod and bolts. The first support frame 12 is located between the rotating disc 23 and the second support frame 43.

[0038] Refer to Figure 1 and Figure 2 , on the edge position of the rotating disc 23, fixing grooves 231 are evenly opened. A chamfer is opened on the side of the fixing groove 231 close to the fixing seat 21. The reaction cup 3 is placed in the fixing groove 231 on the rotating plate; on the side wall of the metal fixing seat 21, a connecting groove 212 corresponding to the position of the reaction cup 3 is opened. A magnetic member 25 is adsorbed and fixed in the connecting groove 212. The magnetic member 25 is a strong magnet. After the antigen in the blood sample in the reaction cup 3 is combined with the magnetic particles, the magnetic member 25 adsorbs and is fixed in the reaction cup 3.

[0039] Refer to Figure 1 and Figure 3, at one end of the first support frame 12 above the rotating disk 23, a cleaning liquid adding hole 123 for adding cleaning liquid is provided, which is on the same axis as the reaction cup 3 placed on the rotating disk 23, and cleaning liquid is added to the reaction cup 3 for cleaning; at one end of the first support frame 12 far from the cleaning liquid adding hole 123, an acid adding hole 124 for adding acid to the reaction cup 3 is provided, which is on the same axis as the reaction cup 3 placed on the rotating disk 23. After the liquid in the reaction cup 3 is cleaned, acid is added to the reaction cup 3 to make the liquid in the reaction cup 3 react.

[0040] Refer to Figure 1 and Figure 3 , a metal fixing block 121 is fixed on the first support frame 12 by bolts. A positioning groove 122 is provided on the fixing block 121 and the first support frame 12 and is in communication. The waste liquid needle 41 on the second support frame 43 is on the same axis as the positioning groove 122. When the waste liquid needle 41 moves towards the rotating disk 23 with the second support frame 43, the waste liquid needle 41 is supported by the positioning groove 122 to prevent the end of the waste liquid needle 41 close to the reaction cup 3 from being offset from the reaction cup 3; an elastic member 411 is fixed between the side of the second support frame 43 close to the rotating disk 23 and the waste liquid needle 41. The elastic member 411 is a spring. When the waste liquid needle 41 moves towards the reaction cup 3, the spring contracts against the fixing block 121, playing a certain buffering role in the waste liquid needle 41 entering the reaction cup 3 and reducing the possibility of the waste liquid needle 41 colliding with the bottom of the reaction cup 3.

[0041] Refer to Figure 1 , Figure 2 and Figure 4 , two connecting plates 421 are fixed on both sides of the connecting frame 42 by bolts. A first connecting plate 521 is lapped on the connecting plates 421. The bent part of the first connecting plate 521 is above the bent part of the connecting plates 421. At one end of the first connecting plate 521 far from the connecting frame 42, a mounting plate 52 is fixedly connected by bolts. The mounting plate 52 is located below the rotating plate, so that the mounting plate 52 moves towards the side close to the rotating plate with the connecting frame 42; on the mounting plates 52 on both sides of the fixed seat 21, cams 51 are rotatably connected by bearings. A second fixing groove 511 is provided at the eccentric position of the cam 51. The second fixing groove 511 contacts the bottom of the reaction cup 3 when the cam 51 moves upward with the mounting plate 52. A groove 213 is provided at the position of the fixed seat 21 corresponding to the cam 51 to prevent the cam 51 from colliding with the fixed seat 21 when the connecting frame 42 drives the first connecting plate 521 and the mounting plate 52 to move upward through the connecting plates 421; a third driving member 53 is fixed on the side of the mounting plate 52 far from the cam 51 by bolts. The third driving member 53 is a driving motor connected to a power source. The driving rod of the third driving member 53 is fixedly connected to the cam 51 by a flat key. The cam 51 is driven to rotate by the third driving member 53, so that the second fixing groove 511 at the eccentric position of the cam 51 drives the reaction cup 3 to shake.

[0042] Reference Figure 1 and Figure 2 Figure 2

[0043] The implementation principle of the embodiment of this application is as follows:

[0044] Place the reaction cup 3 into the positioning groove 122 on the rotating disk 23. The first driving member 24 drives the rotating rod 22 to drive the rotating disk 23 to rotate, so that the reaction cup 3 and the cleaning liquid adding hole 123 on the first support frame 12 are on the same axis. Add cleaning liquid into the reaction cup 3 through the cleaning liquid adding hole 123. Subsequently, the second driving member 44 drives the connecting frame 42 to move upward, so that the connecting frame 42 drives the first connecting plate 521 and the mounting plate 52 to move upward through the second connecting plate 421, so that the second fixing groove 511 formed in the cam 51 on the mounting plate 52 contacts the bottom of the reaction cup 3. The third driving member 53 drives the cam 51 to rotate to shake the reaction cup 3 to mix the liquid in the reaction cup 3; Subsequently, the second driving member 44 drives the connecting frame 42 to move downward, and the second elastic member 523 between the mounting plate 52 and the fixing frame 1 contracts to pull the mounting plate 52 to move downward, so that the cam 51 moves away from the reaction cup 3. The first driving member 24 drives the rotating disk 23 to continue to rotate, and the magnetic member 25 fixed in the connecting groove 212 on the fixing seat 21 adsorbs and fixes the magnetic particles combined with the antigen in the reaction cup 3 in the reaction cup 3. The reaction cup 3 on the rotating disk 23 and the positioning groove 122 on the first support frame 12 are on the same axis; The second driving member 44 drives the connecting frame 42 to continue to move downward, so that the waste liquid needle 41 on the second support frame 43 fixed on the connecting frame 42 moves toward the reaction cup 3 through the positioning groove 122 on the first support frame 12 to extract the waste liquid generated after cleaning in the reaction cup 3. Subsequently, the second driving member 44 drives the connecting frame 42 to move upward to drive the waste liquid needle 41 away from the reaction cup 3; The first driving member 24 drives the rotating disk 23 to continue to rotate, which is on the same axis as the acid adding hole 124 on the first support frame 12, and adds acid into the reaction cup 3 that has discharged waste liquid after cleaning to react with the remaining antigen combined with the magnetic particles in the reaction cup 3; Subsequently, the second driving member 44 drives the connecting frame 42 to continue to move upward, so that the connecting frame 42 drives the mounting plate 52 to move upward, so that the cam 51 on the mounting plate 52 at the same position as the acid adding hole 124 contacts the bottom of the reaction cup 3 after adding acid. The third driving member 53 drives the cam 51 to rotate to drive the reaction cup 3 to shake and shake the liquid in the reaction cup 3. By driving the second driving member 44 to drive the cam 51 on the mounting plate 52 on the connecting frame 42 to move, after the reaction cup 3 placed on the rotating disk 23 is rotated, it can quickly shake the reaction cup 3 after adding cleaning liquid and the reaction cup 3 after adding acid in time, shortening the mixing cycle for mixing the reaction cup 3.

[0045] The embodiments of this specific implementation manner are all preferred embodiments of this application, and do not limit the protection scope of this application accordingly. The same components are denoted by the same reference numerals. Therefore, all equivalent changes made according to the structure, shape, and principle of this application should be covered within the protection scope of this application.

Claims

1. An automatic blood sample testing device, comprising a fixing frame (1), characterized in that: Above the fixing frame (1), there is a magnetic separation component (2) for placing reaction cups (3). Above the magnetic separation component (2), there is a waste liquid discharge component (4) corresponding to the reaction cups (3). On both sides of the fixing frame (1) where the magnetic separation component (2) is located, there are mixing components (5), and the mixing components (5) are in contact with the bottom of the reaction cups (3). The magnetic separation component (2) includes a fixed seat (21) arranged above the fixing frame (1). The fixed seat (21) is provided with a fixing hole (211). A rotating rod (22) is rotatably arranged in the fixing hole (211). Above the fixed seat (21), the rotating rod (22) is fixedly connected with a rotating disc (23). Below the fixing frame (1), there is a driving member one (24) connected and belt-driven to the rotating rod (22). On the edge of the rotating disc (23), there is a fixing groove one (231) corresponding to the reaction cup (3). The fixing groove one (231) is in contact with the edge position of the reaction cup (3), and a chamfer is provided on one side of the fixing groove one (231) close to the fixing frame (1). Above the fixed seat (21) of the fixing frame (1), there is a support frame one (12) connected. The support frame one (12) is located on one side of the waste liquid discharge component (4) close to the rotating disc (23). One end of the support frame one (12) is provided with a cleaning liquid adding hole (123) corresponding to the reaction cup (3), and the other end of the support frame one (12) is provided with an acid adding hole (124) corresponding to the reaction cup (3). The acid adding hole (124) and the cleaning liquid adding hole (123) are on the same axis as the mixing component (5). The waste liquid discharge component (4) includes a waste liquid needle (41). The fixing frame (1) is connected with an installation frame (13) extending upward. The installation frame (13) is slidably connected with a connecting frame (42). The connecting frame (42) is in contact with the mixing component (5). Above the connecting frame (42), there is a support frame two (43) connected. The support frame two (43) is located above the support frame one (12) and is connected with the waste liquid needle (41). Below the fixing frame (1), there is a driving member two (44) connected. The driving rod of the driving member two (44) is fixedly connected with a lead screw (45). The lead screw (45) is rotatably connected with the connecting frame (42). On one side of the support frame one (12) close to the support frame two (43), there is a fixing block (121) connected. The fixing block (121) and the support frame one (12) are provided with a communicating positioning groove (122). The end of the waste liquid needle (41) far from the support frame one (12) is located in the positioning groove (122) and is on the same axis as the reaction cup (3) placed on the rotating disc (23). Between one side of the support frame two (43) close to the rotating disc (23) and the waste liquid needle (41), there is an elastic member one (411) connected. When the driving member two (44) drives the waste liquid needle (41) to move towards the reaction cup (3), the elastic member one (411) abuts against the fixing block (121).

2. The automatic blood sample testing device according to claim 1, characterized in that: A connecting groove (212) is formed in the side wall of the fixed seat (21), and a magnetic member (25) for adsorbing the antigen combined with magnetic particles in the reaction cup (3) is connected and arranged in the connecting groove (212). A groove (213) corresponding to the mixing assembly (5) is formed in the side wall of the fixed seat (21).

3. An automatic blood sample testing device according to claim 1, characterized in that: The mixing assembly (5) includes cams (51) arranged on both sides of the fixed frame (1). An installation plate (52) lapping with the connecting frame (42) is arranged above the fixed frame (1). The cams (51) are rotatably arranged above the installation plate (52). A third driving member (53) for driving the cams (51) to rotate is connected and arranged below the installation plate (52). A second fixed groove (511) in contact with the reaction cup (3) is formed above the cams (51), and the second fixed groove (511) is arranged deviating from the rotation center of the cams (51).

4. An automatic blood sample testing device according to claim 3, characterized in that: One end of the installation plate (52) close to the connecting frame (42) is connected with a first connecting plate (521). Second connecting plates (421) in contact with the first connecting plate (521) are connected to both sides of the connecting frame (42). One ends of the first connecting plate (521) and the second connecting plates (421) close to each other are bent. The bent part of the first connecting plate (521) is located above the bent part of the second connecting plates (421) and lapped with the second connecting plates (421).

5. An automatic blood sample testing device according to claim 4, characterized in that: Protruding members (522) are connected and arranged on both the installation plate (52) and the side wall of the fixed frame (1). An elastic member two (523) is arranged between the protruding members (522), and the elastic member two (523) pulls the installation plate (52) to move towards the position close to the fixed frame (1). A communication groove (14) adapted to the third driving member (53) fixed to the installation plate (52) is formed in the fixed frame (1). A positioning hole (524) is formed in the installation plate (52), and a positioning rod (54) connected to the fixed frame (1) is inserted into the positioning hole (524).

Citation Information

Patent Citations

  • Magnetic cleaning and separating device and method for chemiluminescence immunity analyzer

    CN113770104A

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