Slide rotation alignment fixture for optical pathology slide scanner

Abstract

The application relates to the technical field of fixing devices, and particularly discloses a slide rotation alignment fixing device of an optical pathological section scanner, which comprises a scanner, the scanner comprises a base and a mirror arm fixedly installed on the top of the base, a lens barrel and an object table distributed upwards and downwards are fixedly installed on the front side of the mirror arm, and a vertical guide alignment unit is arranged on the outer side of the lens barrel. The application is characterized in that the installation frame is used to resist the continued downward movement of the moving frame on the rotating disc, four L-shaped clamping plates are synchronously moved close to each other by extrusion control of the extrusion control assembly, four-point constraint is formed on the slide, uniform pressure from four directions is applied to the slide when the L-shaped clamping plates gradually move close to and contact the slide, the uniform pressure forces the slide to slightly move in the horizontal direction until the slide is centered, thereby realizing rotation alignment, accurate centering and deviation rectification, clamping and fixing of the slide, and enabling the slide to be located directly below the objective lens for scanning.

Description

Technical Field

[0001] This invention relates to the field of fixation device technology, and more specifically, to a slide rotation and alignment fixation device for an optical pathology slide scanner. Background Technology

[0002] Optical pathology slide scanners are used in medical and biological research to convert tissue or cell samples from traditional glass slides into high-resolution digital images, improving the efficiency and accuracy of diagnoses for physicians, researchers, and pathologists. The glass slide is an indispensable part of using an optical pathology slide scanner; it is a small, transparent glass slide used to hold biological samples, typically measuring 76mm x 26mm and approximately 1mm thick. During optical pathology slide scanning, to ensure accurate sample placement, the slide must be aligned and fixed directly beneath the scanner for scanning.

[0003] Currently, the common methods for aligning and fixing glass slides include slot-type fixing, mechanical clamp fixing, magnetic fixing, and vacuum adsorption fixing. Among these, the slot-type fixing is the most widely used. This method involves a dedicated slot on the stage, the length of which matches the standard glass slide, while the width is greater than the standard glass slide. This ensures that the slide can be tightly embedded and fixed within the slot, and the slide can be slid back and forth horizontally for adjustment and alignment. However, this method still has certain drawbacks:

[0004] 1. After the slide is inserted into the placement slot, the placement slot limits the slide in the left and right directions and aligns it in the front and back directions. The slide is kept stable in the front and back and vertical directions by the friction between the slide and the slot wall. However, this fixing method is easily affected by external vibration or impact, which may cause the slide to move slightly in the vertical direction or front and back during scanning. This slight movement may cause the image to be blurred or distorted, especially in the case of high magnification imaging or long-term scanning.

[0005] 2. In the placement slot type fixing method, the staff usually observes the position of the slide through the eyepiece and manually slides the slide to align it. However, even if the staff observes the position of the slide through the eyepiece, the resolution of the human eye is still limited, and it is difficult to accurately judge whether the slide is completely centered. Especially in the case of high magnification imaging, a small offset may cause a significant decrease in image quality, and the human eye may not be able to detect these subtle deviations. Summary of the Invention

[0006] This invention provides a slide rotation, alignment, and fixation device for an optical pathology slide scanner, which solves the technical problems in the prior art where the slotted slide is easily affected by external vibration or impact, and the need to improve the accuracy of slide alignment adjustment.

[0007] This invention provides a slide rotation, alignment, and fixing device for an optical pathology slide scanner, comprising a scanner, the scanner including a base and an arm fixedly mounted on the top of the base, a vertically distributed end tube and stage fixedly mounted on the front side of the end tube, a vertical guide alignment unit disposed on the outer side of the end tube, a rotation alignment unit for carrying and controlling the rotation of the slide and two conveyor belts disposed on the top of the stage, the two conveyor belts being symmetrically distributed on both sides of the rotation alignment unit and respectively used for loading and unloading the slides, a self-aligning clamping unit disposed between the vertical guide alignment unit and the rotation alignment unit, the vertical guide alignment unit including a primary drive assembly and a secondary guide assembly, the self-aligning clamping unit including a movable frame connected to the secondary guide assembly, an alignment clamping assembly, a compression control assembly for controlling the alignment clamping assembly, and a locking and clamping assembly.

[0008] The centering clamping assembly includes several return springs 1 fixedly installed at the bottom of the movable frame. The bottom ends of the several return springs 1 are all mounted on a mounting frame. Four return springs 2 in a rectangular distribution are fixedly installed on the inner side of the mounting frame. L-shaped clamps are fixedly installed at the near ends of the four return springs 2.

[0009] The vertical guide alignment unit moves downward and controls the four L-shaped clamps to move closer to the glass slide synchronously through the extrusion control component. At the same time, the locking and clamping component locks the L-shaped clamps, the mounting frame and the moving frame.

[0010] Furthermore, the top of the platform is provided with an installation groove, and the rotation alignment unit includes a rotating shaft rotatably installed on the top of the installation groove and a rotating disk fixedly installed on the top of the rotating shaft. The top surface of the rotating disk, the top surface of the platform, and the top surfaces of the two conveyor belts are all flush with each other.

[0011] Furthermore, the primary drive assembly includes two guide rails symmetrically mounted on the outer side of the lens barrel and an electric slider slidably connected to the guide rails. The secondary guide assembly includes a guide plate fixedly mounted on the side of the electric slider away from the guide rails. The two guide plates are symmetrical to each other, and the moving frame is fixedly mounted on the bottom of the two guide plates.

[0012] Furthermore, guide sleeves are fixedly installed on the rear side of both guide plates, and four sets of guide rods in a rectangular distribution are fixedly installed on the top of the rotating disk. Each set of guide rods has two symmetrical rods. The inner diameter of the guide sleeve is the same as the diameter of the guide rod. When scanning the glass slide, the two guide sleeves cooperate with the two guide rods located on the rear side at this time.

[0013] Furthermore, the extrusion control assembly includes a slide rod fixedly installed on the side of the L-shaped clamp near the mounting frame and sliding through the mounting frame. A driven wedge rod is fixedly installed at the end of the slide rod away from the L-shaped clamp. Four rectangularly distributed drive wedge rods are fixedly installed at the bottom of the movable frame, and the four drive wedge rods cooperate with the corresponding driven wedge rods.

[0014] Furthermore, the locking and clamping assembly includes four mounting plates fixedly installed inside the mounting frame and arranged in a rectangular shape. The four mounting plates are respectively located above four L-shaped clamps. Two mounting rods are fixedly installed at the bottom of the mounting plates, and L-shaped insertion plates are fixedly installed at the bottom of the mounting rods. The two L-shaped insertion plates are perpendicular to each other. The top of the L-shaped clamps has two perpendicular slots, and the two L-shaped insertion plates cooperate with the corresponding slots.

[0015] Furthermore, four rectangularly distributed locking rods are fixedly installed at the bottom of the movable frame, and four return springs are respectively sleeved on the outside of the corresponding locking rods. A locking circular plate is fixedly installed at the bottom end of the locking rod. The top of the rotating disk has four sets of rectangularly distributed locking grooves, each set of four locking grooves. The diameter of the locking circular plate is the same as the diameter of the locking groove. When scanning the glass slide, the four locking circular plates cooperate with the corresponding locking groove located on the rear side at this time.

[0016] Furthermore, the centering clamping assembly also includes a limiting rod that is fixedly installed on the side of the L-shaped clamping plate near the mounting frame and slides through the mounting frame. The limiting rod plays a limiting role during the movement of the L-shaped clamping plate to prevent the L-shaped clamping plate from twisting.

[0017] Furthermore, four rectangular baffles are fixedly installed on the top of the rotating disk, and four sets of rectangular rollers are rotatably installed on the top of the rotating disk. Each set of rollers has three pairs and is driven by an external power source. The left conveyor belt transports the glass slide to the right, and the slide comes into contact with the baffles under the conveying of the rollers, waiting for rotation and alignment.

[0018] Furthermore, a condenser located below the stage is fixedly installed on the front side of the telescope arm, and the eyepiece and objective lens are fixedly installed at both ends of the telescope tube, with the eyepiece located above the objective lens.

[0019] The beneficial effects of this invention are as follows:

[0020] 1. This application utilizes the downward stroke of the moving frame after the mounting bracket contacts the rotating disk, and controls the four L-shaped clamps to approach synchronously through the compression control component, forming a four-point constraint on the slide. As the L-shaped clamps gradually approach and contact the slide, uniform pressure from four directions is applied to the slide. This uniform pressure forces the slide to make a slight displacement in the horizontal direction until the slide is centered, thereby achieving rotational alignment, precise centering correction, clamping and fixing of the slide, so that the slide can be scanned directly below the objective lens, thus improving the scanning accuracy.

[0021] 2. This application establishes a locking mechanism by inserting a locking disc into the locking slot after clamping the slide. This effectively locks the position of the moving frame, preventing it from moving during scanning due to external vibrations or other factors, thus preventing slide displacement. Simultaneously, the L-shaped clamping plate inserted into the slot presses down on the four corners of the slide, ensuring that the slide does not move or shift even slightly during scanning. This dual clamping mechanism provides omnidirectional fixation and locking of the slide in the XYZ axis directions, offering higher clamping force. It is particularly suitable for scanning scenarios requiring high-precision imaging. Furthermore, the L-shaped clamping plate, after being inserted into the slot, also fixes the position of the L-shaped clamp, preventing it from loosening during scanning due to external vibrations or other factors, thereby further improving the clamping stability of the slide.

[0022] 3. This application provides dual guidance for the moving frame and the mounting frame during the descent of the moving frame. The dual guidance mechanism ensures that the moving frame and the mounting frame maintain a stable movement trajectory during the descent, so that the clamping center of the centering clamping component can always remain concentric with the lens barrel and the objective lens located on the rear side, thereby ensuring that the subsequent centering clamping can be more accurate. Attached Figure Description

[0023] Figure 1 This is a three-dimensional structural diagram of the present invention.

[0024] Figure 2 This is the present invention. Figure 1 A magnified view of part A in the middle.

[0025] Figure 3 This is a three-dimensional structural diagram of the rotating disk, glass slide, locking groove, roller and baffle of the present invention.

[0026] Figure 4 This is an exploded three-dimensional view of the movable frame, mounting frame, reset spring one, reset spring two, and L-shaped clamping plate of the present invention.

[0027] Figure 5 This is a three-dimensional structural diagram of the self-centering clamping unit of the present invention.

[0028] Figure 6This is a three-dimensional structural diagram of the reset spring 1, mounting bracket, reset spring 2, and L-shaped clamping plate of the present invention.

[0029] In the diagram: 1. Scanner; 101. Base; 102. Arm; 103. Stage; 104. Lens tube; 105. Eyepiece; 106. Objective lens; 107. Condenser; 2. Conveyor belt; 3. Baffle; 4. Rotary alignment unit; 5. Vertical guide alignment unit; 6. Self-centering clamp unit; 7. Roller; 8. Slide; 401. Rotating shaft; 402. Rotating disk; 501. Primary drive assembly; 502. Secondary guide assembly; 5011. Guide rail; 5012. Electric slider; 5021. Guide plate; 5022. Guide sleeve; 5023. 601. Guide rod; 602. Moving frame; 603. Centering clamping assembly; 604. Extrusion control assembly; 605. Locking and pressing assembly; 606. Return spring one; 607. Mounting frame; 608. Return spring two; 609. L-shaped clamping plate; 6000. Limiting rod; 6000. Drive wedge rod; 6000. Slide rod; 6000. Driven wedge rod; 6000. Mounting plate; 6000. Mounting rod; 6000. L-shaped insertion plate; 6000. Slot; 6000. Locking rod; 6000. Locking round plate; 6000. Locking groove. Detailed Implementation

[0030] The subject matter described herein will now be discussed with reference to exemplary embodiments. It should be understood that these embodiments are discussed to enable those skilled in the art to better understand and implement the subject matter described herein. Changes may be made to the function and arrangement of the elements discussed without departing from the scope of this specification. Various processes or components may be omitted, substituted, or added as needed in the examples. Furthermore, features described in some examples may be combined in other examples.

[0031] See Figure 1 , Figure 3 and Figure 5This embodiment proposes a slide rotation, alignment, and fixing device for an optical pathology slide scanner, including a scanner 1. The scanner 1 includes a base 101 and a microscope arm 102 fixedly mounted on the top of the base 101. A microscope tube 104 and a stage 103, distributed vertically, are fixedly mounted on the front side of the microscope arm 102. A condenser 107 located below the stage 103 is fixedly mounted on the front side of the microscope arm 102. An eyepiece 105 and an objective lens 106 are respectively provided at both ends of the microscope tube 104, with the eyepiece 105 located above the objective lens 106. A vertical guide alignment unit 5 is provided on the outer side of the microscope tube 104. The top of the stage 103 is provided with... The system includes a rotary alignment unit 4 for carrying and controlling the rotation of the glass slide 8, and two conveyor belts 2. The two conveyor belts 2 are symmetrically distributed on both sides of the rotary alignment unit 4 and are used for loading and unloading the glass slide 8. A self-centering clamping unit 6 is provided between the vertical guide alignment unit 5 and the rotary alignment unit 4. The vertical guide alignment unit 5 includes a primary drive assembly 501 and a secondary guide assembly 502. The self-centering clamping unit 6 includes a movable frame 601 connected to the secondary guide assembly 502, a centering clamping assembly 602, a compression control assembly 603 for controlling the centering clamping assembly 602, and a locking and pressing assembly 604.

[0032] See Figure 1 and Figure 3 The top of the platform 103 is provided with a mounting groove. The rotation alignment unit 4 includes a rotating shaft 401 rotatably mounted on the top of the mounting groove and a rotating disk 402 fixedly mounted on the top of the rotating shaft 401. The rotating shaft 401 is connected to an external power source. The top surfaces of the rotating disk 402, the platform 103, and the two conveyor belts 2 are all flush with each other. Four rectangularly distributed baffles 3 are fixedly mounted on the top of the rotating disk 402, and four rectangularly distributed sets of rollers 7 are rotatably mounted on the top of the rotating disk 402. Each set of rollers 7 is equipped with... There are three pairs of objective lenses 106, which are driven by an external power source. The left conveyor belt 2 transports the glass slide 8 to the right and the slide 8 is brought into contact with the baffle 3 by the roller 7, so that it can wait for rotation and alignment. There are three objective lenses 106 arranged around the circumference and are rotatably connected to the lens barrel 104 through the adjustment disk. The objective lens 106 located on the rear side is concentric with the lens barrel 104. The included angle between two adjacent objective lenses 106 is 120°. The objective lens 106 concentric with the lens barrel 104 can be switched by rotating the adjustment disk. The objective lens 106 concentric with the lens barrel 104 is the objective lens 106 used for scanning.

[0033] See Figure 1 and Figure 3The primary drive assembly 501 includes two guide rails 5011 symmetrically mounted on the outer side of the lens barrel 104 and an electric slider 5012 slidably connected to the guide rails 5011. The secondary guide assembly 502 includes a guide plate 5021 fixedly mounted on the side of the electric slider 5012 away from the guide rails 5011. The two guide plates 5021 are symmetrical to each other. The moving frame 601 is fixedly mounted on the bottom of the two guide plates 5021.

[0034] See Figure 1 , Figure 3 and Figure 5 Guide sleeves 5022 are fixedly installed on the rear side of both guide plates 5021. Four sets of guide rods 5023 with rectangular distribution are fixedly installed on the top of the rotating disk 402. Each set of guide rods 5023 has two symmetrically arranged rods. The inner diameter of the guide sleeve 5022 is the same as the diameter of the guide rod 5023. When scanning the glass slide 8, the two guide sleeves 5022 cooperate with the two guide rods 5023 located on the rear side at this time. The centering clamping assembly 602 includes several return springs 6021 fixedly installed at the bottom of the moving frame 601. The bottom ends of the several return springs 6021 are jointly installed with the mounting bracket 6022.

[0035] In practical use, the pathological slide 8 to be scanned is first transported to the right by the left conveyor belt 2 and moved by the roller 7 until it abuts against the left baffle 3. Then, the rotating shaft 401 is driven by an external power source to rotate 90° clockwise, causing the slide 8, which is abutting against the left baffle 3, to rotate 90° clockwise. This moves the slide 8 to a position below the objective lens 106, which is concentric with the microscope tube 104 (i.e., the objective lens 106 is located at the rear). However, due to the inertial force during rotation, the slide 8 may experience a slight displacement, causing it to deviate from being directly below the rear objective lens 106. Next, the electric slider 5012 is controlled to move downward along the guide rail 5011, causing the two electric sliders 5012 to move downward synchronously, thereby driving the two guide plates 502. 1. Moving downwards causes the movable frame 601 to move downwards, which in turn causes the mounting frame 6022 to move downwards. As the movable frame 601 gradually moves downwards, the guide sleeve 5022 slides and is fitted onto the outside of the guide rod 5023 and continues to move downwards under the guidance of the guide rod 5023. This forms a double guide for the movable frame 601 and the mounting frame 6022. The double guide mechanism ensures that the movable frame 601 and the mounting frame 6022 maintain a stable trajectory during descent, so that the clamping center of the centering clamping assembly 602 can always remain concentric with the lens barrel 104 and the objective lens 106 located on the rear side. This ensures that the subsequent centering clamping can be more accurate. When the mounting frame 6022 abuts against the rotating disk 402, the centering clamping assembly 602 is distributed on the outside of the four right-angled sides of the slide 8.

[0036] See Figure 2, Figure 4 , Figure 5 and Figure 6 The centering clamping assembly 602 also includes four return springs 6023 fixedly installed inside the mounting bracket 6022 and arranged in a rectangular shape. Each of the four return springs 6023 has an L-shaped clamping plate 6024 fixedly installed at one end. The inner side of the L-shaped clamping plate 6024 is provided with a silicone anti-slip pad, which can gently clamp the glass slide 8 when clamping it, avoiding physical damage to the glass slide 8.

[0037] See Figure 2 , Figure 4 , Figure 5 and Figure 6 The centering clamping assembly 602 further includes a limiting rod 6025 fixedly installed on the side of the L-shaped clamping plate 6024 near the mounting frame 6022 and sliding through the mounting frame 6022. The limiting rod 6025 plays a limiting role during the movement of the L-shaped clamping plate 6024 to prevent the L-shaped clamping plate 6024 from twisting.

[0038] See Figure 2 , Figure 4 , Figure 5 and Figure 6 The extrusion control assembly 603 includes a slide rod 6032 fixedly installed on the side of the L-shaped clamp 6024 near the mounting frame 6022 and sliding through the mounting frame 6022. A driven wedge rod 6033 is fixedly installed at the end of the slide rod 6032 away from the L-shaped clamp 6024. Four rectangularly distributed drive wedge rods 6031 are fixedly installed at the bottom of the moving frame 601. The four drive wedge rods 6031 cooperate with the corresponding driven wedge rods 6033.

[0039] In practical use, after the mounting bracket 6022 contacts the rotating disk 402, the moving bracket 601 continues to move and begins to compress the return spring 6021, which in turn drives the drive wedge rod 6031 to continue moving downward and presses the driven wedge rod 6033. This causes the driven wedge rod 6033 to slide the L-shaped clamping plate 6024 towards the side closer to the slide 8 under the limit of the limiting rod 6025, so that the four L-shaped clamping plates 6024 simultaneously approach the slide 8 and stretch the return spring 6023. As the L-shaped clamping plates 6024 gradually approach the slide 8, due to the four... L-shaped clamps 6024 are located on the outer sides of the four right-angled sides of the slide 8, forming a "four-point constraint" system. When the L-shaped clamps 6024 gradually approach and contact the slide 8, they apply uniform pressure from four directions to the slide 8. This uniform pressure forces the slide 8 to make a slight displacement in the horizontal direction until the slide 8 is centered (that is, adjusted to be directly below the rear objective lens 106), thereby realizing the rotational alignment, precise centering correction, clamping and fixing of the slide 8, so that the slide 8 can be scanned directly below the objective lens 106.

[0040] See Figure 2 , Figure 4 , Figure 5 and Figure 6 The locking and clamping assembly 604 includes four mounting plates 6041 fixedly installed inside the mounting bracket 6022 and arranged in a rectangular shape. The four mounting plates 6041 are respectively located above four L-shaped clamping plates 6024. Two mounting rods 6042 are fixedly installed at the bottom of the mounting plates 6041. An L-shaped insertion plate 6043 is fixedly installed at the bottom end of the mounting rod 6042. The two L-shaped insertion plates 6043 are perpendicular to each other. Two mutually perpendicular slots 6044 are opened at the top of the L-shaped clamping plates 6024. The two L-shaped insertion plates 6043 are respectively engaged with the corresponding slots 6044.

[0041] See Figure 2 , Figure 3 , Figure 5 and Figure 6 The bottom of the movable frame 601 is fixedly equipped with four rectangularly distributed locking rods 6045, and four return springs 6021 are respectively sleeved on the outside of the corresponding locking rods 6045. The bottom end of the locking rods 6045 is fixedly equipped with locking circular plates 6046. The top of the rotating disk 402 is provided with four sets of rectangularly distributed locking grooves 6047, each set of locking grooves 6047 consisting of four rectangularly distributed grooves. The diameter of the locking circular plates 6046 is the same as the diameter of the locking grooves 6047. When scanning the glass slide 8, the four locking circular plates 6046 cooperate with the corresponding locking grooves 6047 located on the rear side at this time.

[0042] In practical use, after clamping and fixing the slide 8, the moving frame 601 continues to move downwards, thereby driving the mounting rod 6042 and locking rod 6045 downwards. This causes the L-shaped insertion plate 6043 and locking disc 6046 to continue moving downwards until the L-shaped insertion plate 6043 is inserted into the slot 6044 and the locking disc 6046 is inserted into the locking groove 6047. At this point, the electric slider 5012 stops moving, causing the moving frame 601 to stop moving as well. The locking disc 6046, inserted into the locking groove 6047, forms a locking mechanism, effectively locking the position of the moving frame 601. This ensures that the moving frame 601 remains stationary throughout the scanning process, preventing it from rebounding or moving due to external vibrations or other factors, which could cause the slide 8 to shift. The stability of the slide 8 is particularly crucial in high-magnification imaging or long-duration scanning. Even the slightest displacement can affect image quality. Simultaneously, the L-shaped clamping plate 6043, inserted into the slot 6044, presses down on the four corners of the slide 8, ensuring that the slide 8 does not move or shift during scanning. This dual clamping mechanism (L-shaped clamping plate 6024 and L-shaped clamping plate 6043) provides all-around fixation and locking of the slide 8 along the XYZ axes, offering higher clamping force. It is particularly suitable for scanning scenarios requiring high-precision imaging. Furthermore, after the L-shaped clamping plate 6043 is inserted into the slot 6044, it not only presses down on the slide 8 but also fixes the position of the L-shaped clamping plate 6024, preventing it from loosening due to external vibration or other factors during scanning. This further improves the clamping stability of the slide 8. Finally, the pathological section on top of the slide 8 is scanned through the objective lens 106.

[0043] After scanning, the electric slider 5012 is moved upward to reset. As the electric slider 5012 moves upward, it drives the moving frame 601 to reset. First, the pressure on the reset spring 6021 decreases, and it gradually extends. At the same time, the locking rod 6045, the locking circular plate 6046, and the L-shaped clamping plate 6043 move upward synchronously to reset until the reset spring 6021 is fully reset. During this process, the driving wedge rod 6031 also moves upward synchronously and gradually disengages from the driven wedge rod 6033, causing the reset spring 6023 to gradually reset, driving the L-shaped clamping plate 6024 and... The driven wedge rod 6033 is reset, causing the L-shaped clamp 6024 to release its clamping and fixing of the glass slide 8. Finally, the moving frame 601 continues to move upward, which will drive the mounting frame 6022 to move upward and disengage from the rotating disk 402. Then, the rotating shaft 401 is driven to rotate by an external power source, causing the rotating disk 402 to rotate 90° clockwise, so that the scanned glass slide 8 rotates to the right side of the rotating disk 402. Then, the roller 7 located on the right side is driven to rotate by an external power source, which drives the scanned glass slide 8 to be transported to the top of the right conveyor belt 2, and the glass slide 8 is transported out by the right conveyor belt 2.

[0044] It should be noted that after the moving frame 601 is reset, it will be fitted over the outer side of the rear objective lens 106, and the two front objective lenses 106 will be located outside the moving frame 601. During scanning, the moving frame 601 is located below the three objective lenses 106. If it is necessary to rotate and adjust the objective lenses 106, the moving frame 601 will not cause any obstruction.

[0045] Finally, it should be noted that the above embodiments are merely examples for clearly illustrating the present invention and are not intended to limit the implementation. Those skilled in the art will recognize that other variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations. However, obvious variations or modifications derived therefrom are still within the scope of protection of this invention.

Claims

1. A slide rotation, alignment, and fixation device for an optical pathology slide scanner, characterized in that, include: The scanner (1) includes a base (101) and a mirror arm (102) fixedly installed on the top of the base (101). The front side of the mirror arm (102) is fixedly installed with a mirror tube (104) and a stage (103) distributed vertically. A vertical guide alignment unit (5) is provided on the outside of the mirror tube (104). The top of the stage (103) is provided with a rotation alignment unit (4) for carrying and controlling the rotation of the glass slide (8) and two conveyor belts (2). The two conveyor belts (2) are symmetrically distributed on both sides of the rotation alignment unit (4) and are used to load and unload the glass slide (8) respectively. A self-aligning clamping unit (6) is provided between the vertical guide alignment unit (5) and the rotary alignment unit (4). The vertical guide alignment unit (5) includes a primary drive assembly (501) and a secondary guide assembly (502). The self-aligning clamping unit (6) includes a movable frame (601) connected to the secondary guide assembly (502), an alignment clamping assembly (602), a compression control assembly (603) for controlling the alignment clamping assembly (602), and a locking and pressing assembly (604). The centering clamping assembly (602) includes several return springs (6021) fixedly installed at the bottom of the movable frame (601), and a mounting frame (6022) is installed at the bottom of the several return springs (6021). Four return springs (6023) in a rectangular distribution are fixedly installed on the inner side of the mounting frame (6022). An L-shaped clamp (6024) is fixedly installed at one end of each of the four return springs (6023). The vertical guide alignment unit (5) moves down and controls the four L-shaped clamps (6024) to move closer to the glass slide (8) synchronously through the extrusion control component (603). At the same time, the locking and clamping component (604) locks the L-shaped clamps (6024), the mounting bracket (6022) and the moving bracket (601). The stage (103) has a mounting groove on its top. The rotation alignment unit (4) includes a rotating shaft (401) rotatably mounted on the top of the mounting groove and a rotating disk (402) fixedly mounted on the top of the rotating shaft (401). The primary drive assembly (501) includes two guide rails (5011) symmetrically mounted on the outside of the lens barrel (104) and an electric slider (5012) slidably connected to the guide rails (5011). The secondary guide assembly (502) includes a guide plate (5021) fixedly mounted on the side of the electric slider (5012) away from the guide rails (5011). Guide sleeves (5022) are fixedly mounted on the rear side of both guide plates (5021). The top of (402) is fixedly equipped with four sets of rectangular guide rods (5023), each set of guide rods (5023) has two symmetrical rods, and the inner diameter of the guide sleeve (5022) is the same as the diameter of the guide rod (5023); the front side of the lens arm (102) is fixedly equipped with a condenser (107) located below the stage (103), and the two ends of the lens tube (104) are respectively equipped with an eyepiece (105) and an objective lens (106), and the eyepiece (105) is located above the objective lens (106); the top of the rotating disk (402) is fixedly equipped with four rectangular baffles (3), and the top of the rotating disk (402) is rotatably equipped with four sets of rectangular rollers (7).

2. The slide rotation, alignment, and fixation device for an optical pathology slide scanner according to claim 1, characterized in that, The top surfaces of the rotating disk (402), the platform (103), and the two conveyor belts (2) are all flush with each other.

3. The slide rotation, alignment, and fixation device for an optical pathology slide scanner according to claim 1, characterized in that, The two guide plates (5021) are symmetrical to each other, and the movable frame (601) is fixedly installed at the bottom of the two guide plates (5021).

4. The slide rotation, alignment, and fixation device for an optical pathology slide scanner according to claim 3, characterized in that, The two guide sleeves (5022) cooperate with the two guide rods (5023) located at the rear side when scanning the slide (8).

5. The slide rotation, alignment, and fixation device for an optical pathology slide scanner according to claim 2, characterized in that, The extrusion control assembly (603) includes a slide rod (6032) fixedly installed on the side of the L-shaped clamp (6024) near the mounting frame (6022) and sliding through the mounting frame (6022). A driven wedge rod (6033) is fixedly installed at the end of the slide rod (6032) away from the L-shaped clamp (6024). Four rectangularly distributed drive wedge rods (6031) are fixedly installed at the bottom of the moving frame (601). The four drive wedge rods (6031) cooperate with the corresponding driven wedge rods (6033).

6. The slide rotation, alignment, and fixing device for an optical pathology slide scanner according to claim 5, characterized in that, The locking and clamping assembly (604) includes four mounting plates (6041) fixedly installed inside the mounting bracket (6022) and arranged in a rectangular shape. The four mounting plates (6041) are respectively located above four L-shaped clamps (6024). Two mounting rods (6042) are fixedly installed at the bottom of the mounting plate (6041). An L-shaped insertion plate (6043) is fixedly installed at the bottom end of the mounting rod (6042). The two L-shaped insertion plates (6043) are perpendicular to each other. The top of the L-shaped clamp (6024) is provided with two mutually perpendicular slots (6044). The two L-shaped insertion plates (6043) are respectively engaged with the corresponding slots (6044).

7. The slide rotation, alignment, and fixing device for an optical pathology slide scanner according to claim 5, characterized in that, The bottom of the movable frame (601) is fixedly equipped with four rectangularly distributed locking rods (6045), and four return springs (6021) are respectively sleeved on the outside of the corresponding locking rods (6045). The bottom end of the locking rods (6045) is fixedly equipped with locking round plates (6046). The top of the rotating disk (402) is provided with four sets of rectangularly distributed locking grooves (6047). Each set of locking grooves (6047) consists of four rectangularly distributed grooves. The diameter of the locking round plates (6046) is the same as the diameter of the locking grooves (6047). When scanning the glass slide (8), the four locking round plates (6046) cooperate with the corresponding locking grooves (6047) located on the rear side at this time.

8. The slide rotation, alignment, and fixation device for an optical pathology slide scanner according to claim 5, characterized in that, The centering clamping assembly (602) further includes a limiting rod (6025) fixedly installed on the side of the L-shaped clamp (6024) near the mounting frame (6022) and sliding through the mounting frame (6022). The limiting rod (6025) plays a limiting role during the movement of the L-shaped clamp (6024) to prevent the L-shaped clamp (6024) from twisting.

9. The slide rotation, alignment, and fixing device for an optical pathology slide scanner according to claim 2, characterized in that, Each set of rollers (7) is equipped with three pairs and driven by an external power source. The left conveyor belt (2) transports the glass slide (8) to the right and it comes into contact with the baffle (3) under the conveying of the rollers (7) to wait for rotation and alignment.

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