Composition comprising skin care active ingredient or cellulose compound

Abstract

The present invention relates to a composition comprising: (a) at least one oil; (b) at least one diol having at least one carbon chain comprising 3 or more carbon atoms; (c) (c1) at least one skin care active ingredient or (c2) at least one cellulose compound; and (d) water. The composition according to the present invention can enhance or improve the penetration of the ingredient (c1) into the skin compared to the case in which the ingredient (b) is not used. The composition according to the present invention can enhance the gloss of the skin while providing a fresh texture when used compared to where no ingredient (c2) is used.

Description

Technical Field The present invention relates to a composition, preferably a cosmetic composition, and more preferably a dermocosmetic composition, comprising at least one skin care active ingredient or at least one cellulose compound. Background Art Firstly, there is a wide variety of skin care active ingredients used in the field of cosmetic and dermatological compositions.

[0003] Skin care active ingredients are preferably absorbed by the skin or penetrate into the skin as much as possible. However, due to the barrier function of the skin, skin absorption or skin penetration of such skin care active ingredients is not easy. Therefore, one possible method to enhance the skin penetration of skin care active ingredients may be to use a skin penetration enhancer together with the skin care active ingredients.

[0004] For example, WO 2018 / 097303 uses a combination of a single polyglycerol fatty acid ester and niacinamide in a nanoemulsion or microemulsion containing ceramide to enhance the skin penetration of ceramide.

[0005] Secondly, glowing skin is one of the important demands of consumers found in many countries such as China, Japan, and the United States.

[0006] Oil-based cosmetic products have been used to enhance the radiance of the skin. However, there are technical challenges: Oil-based cosmetic products often provide an unpleasant touch when used, such as a greasy texture. On the other hand, generally speaking, water-based cosmetic products can provide a non-greasy yet refreshing texture. However, it is difficult for water-based cosmetic products to enhance the radiance of the skin.

[0007] JP-B-3774180 discloses (see its Examples section) certain specific dermatological compositions comprising N-acyl sarcosinate alkyl esters, specific diols and 12-hydroxystearic acid. However, JP-B-3774180 does not teach the use of cellulose or cellulose derivatives in order to enhance the radiance of the skin.

[0008] JP-A-2004-75639 also discloses (see its Examples section) some specific dermatological compositions comprising viscous oil, N-acyl sarcosinate alkyl ester and specific diols. However, JP-A-2004-75639 does not teach the use of cellulose or cellulose derivatives in order to enhance the glossiness of the skin.

[0009] Disclosure of the Invention There is a need for compositions comprising skin care actives based on new skin penetration enhancers which can enhance or improve the penetration of the skin care actives into the skin.

[0010] Furthermore, there is an additional need for compositions comprising oils that can enhance skin radiance while providing a refreshing texture upon use.

[0011] It is a first object of the present invention to provide compositions that enhance or improve the penetration of skin care active ingredients into the skin.

[0012] A second object of the present invention is to provide a composition comprising oils which can enhance the radiance of the skin while providing a refreshing texture upon use.

[0013] The above first object or the second object of the present invention can be achieved by using a composition comprising the following components: (a) at least one oil; (b) at least one diol having at least one carbon chain containing 3 or more carbon atoms; (c) (c1) at least one skin care active ingredient or (c2) at least one cellulose compound; and (d) Water.

[0014] (a) The oil may be selected from (i) fatty alcohols, (ii) fatty acids, (iii) monocarboxylic acid monoesters, (iv) dicarboxylic acid diesters, (v) N-acylamino acid esters and (vi) alkyl lactates, provided that: - (i) fatty alcohols and (ii) fatty acids contain branched alkyl groups, or straight or branched alkenyl groups, each of which has 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, - (iii) the monocarboxylic acid monoester contains a branched alkyl group, or a straight or branched alkenyl group, each of which has 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, - (iv) the dicarboxylic acid diester comprises at least one branched alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms; and an alkenyl group having 6 to 18 carbon atoms, preferably 6 to 14 carbon atoms, and more preferably 6 to 10 carbon atoms, -(v) the N-acyl amino acid ester comprises a branched alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms; and a straight or branched acyl group having 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, and - (vi) The alkyl lactate contains a linear or branched alkyl group or a linear or branched alkenyl group, each of which has 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms.

[0015] The (a) oil may be selected from (v) N-acylamino acid esters containing at least a branched alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms, preferably (v) N-acylamino acid esters represented by the following general formula (5): R 2 -N(R 5 )-CH(R 6 )-(CH2) n -COO-R 3 (5) in R 2 represents a straight-chain or branched acyl group having 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, R 3 represents a branched alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms, R 5 represents a hydrogen atom or a straight-chain or branched alkyl group having 1 to 4 carbon atoms, R 6 represents a hydrogen atom or a straight or branched alkyl group having 1 to 4 carbon atoms which may be substituted with a hydroxyl group or a phenyl group, and n represents an integer from 0 to 2, And more preferably, the (a) oil is isopropyl lauroyl sarcosinate.

[0016] The amount of (a) oil in the composition according to the invention may range from 0.5% to 25% by weight, preferably from 1% to 20% by weight and more preferably from 2% to 15% by weight relative to the total weight of the composition.

[0017] (b) The diol having at least one carbon chain containing 3 or more carbon atoms may be selected from propylene glycol, dipropylene glycol, polypropylene glycol, butylene glycol, dibutylene glycol, polybutylene glycol, pentylene glycol, dipentylene glycol, hexylene glycol, dihexylene glycol, and mixtures thereof.

[0018] The weight ratio of the amount of (b) diol having at least one carbon chain containing 3 or more carbon atoms to the amount of (a) oil may be 4 or more, preferably 5 or more, and more preferably 6 or more.

[0019] The (c1) skin care active ingredient may have a Log P value of 4 or less, preferably -4.5 to 4.0, and more preferably -4.0 to 3.5.

[0020] (c1) The skin care active ingredient may be a skin care cosmetic active ingredient, preferably a skin whitening or anti-wrinkle ingredient, and more preferably selected from ascorbyl glucoside, 3-O-ethylascorbic acid, tranexamic acid, hydroxypropyltetrahydropyrantriol, niacinamide, salicylic acid, phenethylresorcinol, and mixtures thereof.

[0021] The amount of (c1) skin care active ingredient in the composition according to the invention may range from 0.01% to 25%, preferably from 0.05% to 20% and more preferably from 0.1% to 15% by weight relative to the total weight of the composition.

[0022] The (c2) cellulose compound may be selected from unmodified cellulose and nonionic cellulose ethers or anionic cellulose ethers.

[0023] (c2) The cellulose compound may be selected from cellulose, cellulose gum, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, sodium carboxymethyl cellulose, and mixtures thereof.

[0024] The amount of (c2) cellulose compound in the composition according to the invention may range from 0.01% to 40%, preferably from 0.05% to 35% and more preferably from 0.1% to 30% by weight relative to the total weight of the composition.

[0025] The composition according to the present invention may have a turbidity of 120 NTU or less, preferably 90 NTU or less and more preferably 60 NTU or less.

[0026] The composition according to the present invention may be a cosmetic composition, preferably a skin cosmetic composition, and more preferably a skin care cosmetic composition.

[0027] The invention also relates to a cosmetic method for treating keratinous materials, preferably the skin, comprising the step of applying a composition according to the invention.

[0028] Best Mode for Carrying Out the Invention After diligent research, the inventors have discovered that it is possible to provide a composition that can enhance or improve the penetration of skin care active ingredients into the skin by using a new skin penetration enhancer, and that it is possible to provide a composition that contains oil and can enhance the radiance of the skin while providing a fresh texture when used.

[0029] Therefore, the present invention relates to a composition comprising: (a) at least one oil; (b) at least one diol having at least one carbon chain containing 3 or more carbon atoms; (c) (c1) at least one skin care active ingredient or (c2) at least one cellulose compound; and (d) Water.

[0030] If the composition according to the invention comprises (c1) at least one skin care active ingredient, the composition according to the invention can enhance or improve the penetration of (c1) skin care active ingredient into the skin compared to the case in which ingredient (b) is not used.

[0031] (b) at least one diol having at least one carbon chain containing 3 or more carbon atoms can act as a skin penetration enhancer for the (c1) skin care active ingredient.

[0032] The composition according to the invention comprises at least one oil. Thus, the composition according to the invention can enhance the radiance of the skin when applied to the skin.

[0033] If the composition according to the invention comprises (c2) at least one cellulose compound, the composition according to the invention can further enhance the radiance of the skin while providing a fresh texture upon use compared to the case where ingredient (c2) is not used.

[0034] (c2) At least one cellulose compound can act as a skin radiance enhancing agent.

[0035] The composition according to the invention may comprise a relatively large amount of oil. Therefore, the composition according to the invention may provide better cosmetic effects resulting from the relatively large amount of oil, such as further enhanced skin radiance.

[0036] The composition according to the invention may also provide a fresh texture upon use. Thus, the composition according to the invention may provide a less greasy texture.

[0037] The compositions according to the invention are stable over time, even under temperature changes (for example from high to low temperatures and vice versa), so that they do not cause any phase separation, while maintaining a homogeneous appearance.

[0038] The composition according to the invention may be transparent or slightly translucent, but is preferably transparent.

[0039] The composition according to the present invention need not contain any surfactant. Therefore, the amount of surfactant in the composition may be limited to, for example, 1 wt % or less, preferably 0.1 wt % or less, and more preferably 0.01 wt % or less, relative to the total weight of the composition. Most preferably, the composition according to the present invention does not contain a surfactant.

[0040] Surfactants are known to provide a greasy texture as well as irritation to the skin.

[0041] Thus, a composition according to the invention may provide an even less greasy texture if the composition according to the invention comprises only a limited amount of surfactant.

[0042] Furthermore, the composition according to the invention may provide less irritation to the skin if the composition according to the invention comprises only a limited amount of surfactant.

[0043] Hereinafter, the composition according to the present invention will be explained in a more detailed manner.

[0044] [Oil] The composition according to the invention may comprise (a) at least one oil. If two or more oils are used, they may be the same or different.

[0045] Here, "oil" means a fatty compound or substance which is in the form of a liquid or paste (not solid) at room temperature (25° C.) under atmospheric pressure (760 mmHg). As the oil, those generally used in cosmetics can be used alone or in combination. These oils may be volatile or nonvolatile.

[0046] (a) The oil may be a non-polar oil such as hydrocarbon oil, silicone oil, etc.; a polar oil such as vegetable oil or animal oil, and ester oil or ether oil; or a mixture thereof.

[0047] (a) The oil may be selected from oils of vegetable or animal origin, synthetic oils, silicone oils, hydrocarbon oils and fatty alcohols.

[0048] As examples of vegetable oils, mention may be made of, for example, linseed oil, camellia oil, macadamia oil, corn oil, mink oil, olive oil, avocado oil, tea oil, castor oil, safflower oil, jojoba oil, sunflower oil, almond oil, rapeseed oil, sesame oil, soybean oil, peanut oil, and mixtures thereof.

[0049] As examples of animal oils, mention may be made of, for example, squalene and squalane.

[0050] As examples of synthetic oils, mention may be made of alkane oils, such as isododecane and isohexadecane, ester oils, ether oils and artificial triglycerides.

[0051] The ester oil is preferably a saturated or unsaturated linear or branched C1-C 26 Aliphatic monobasic or polybasic acids and saturated or unsaturated linear or branched C1-C 26 Liquid esters of aliphatic monohydric or polyhydric alcohols, the total number of carbon atoms in the ester being greater than or equal to 10.

[0052] Preferably, for esters of monohydric alcohols, at least one of the alcohol and the acid from which the esters of the present invention are derived is branched.

[0053] Among the monoesters of monoacids and monoalcohols, mention may be made of ethyl palmitate, ethylhexyl palmitate, isopropyl palmitate, dicaprylyl carbonate; alkyl myristates, for example isopropyl myristate or ethyl myristate; isocetyl stearate, 2-ethylhexyl isononanoate, isononyl isononanoate, isodecyl neopentanoate and isostearyl neopentanoate.

[0054] You can also use C4-C 22 Dicarboxylic or tricarboxylic acids with C1-C 22 Esters of alcohols; and esters of monocarboxylic acids, dicarboxylic acids or tricarboxylic acids with non-sugar C4-C 26 Esters of dihydric alcohols, trihydric alcohols, tetrahydric alcohols or pentahydric alcohols.

[0055] Mention may be made in particular of: diethyl sebacate; isopropyl lauroyl sarcosinate; diisopropyl sebacate; bis(2-ethylhexyl) sebacate; diisopropyl adipate; di-n-propyl adipate; dioctyl adipate; bis(2-ethylhexyl) adipate; diisostearyl adipate; bis(2-ethylhexyl) maleate; triisopropyl citrate; triisocetyl citrate; triisostearyl citrate; glyceryl trilactate; tricaprylin; tri(octyldodecyl) citrate; trioleyl citrate; neopentyl glycol diheptanoate; and diethylene glycol diisononanoate.

[0056] As ester oils, one can use C6-C 30 (and preferably C 12 -C 22 ) Sugar esters and diesters of fatty acids. Recall that the term "sugar" means a hydrocarbon-based compound carrying oxygen, which contains several alcohol functions, with or without aldehyde or ketone functions, and which contains at least 4 carbon atoms. These sugars can be monosaccharides, oligosaccharides or polysaccharides.

[0057] Examples of suitable sugars that may be mentioned include sucrose (saccharose), glucose, galactose, ribose, fucose, maltose, fructose, mannose, arabinose, xylose and lactose, and derivatives thereof, in particular alkyl derivatives, such as methyl derivatives, for example methyl glucose.

[0058] The sugar esters of fatty acids can be selected in particular from the sugars described above and linear or branched saturated or unsaturated C6-C 30 (and preferably C 12 -C 22 ) esters or mixtures of esters of fatty acids. If these compounds are unsaturated, they may have 1 to 3 conjugated or non-conjugated carbon-carbon double bonds.

[0059] The esters according to this variant may also be chosen from monoesters, diesters, triesters, tetraesters and polyesters, and mixtures thereof.

[0060] These esters may be, for example, oleate, laurate, palmitate, myristate, behenate, cocoate, stearate, linoleate, linolenate, caprate and arachidonate, or mixtures thereof, in particular oleyl palmitate, oleostearate and palmitostearate mixed esters, and pentaerythritol tetra(ethylhexanoate).

[0061] More particularly, use is made of the monoesters and diesters, and in particular the mono- or dioleates, stearates, behenates, oleopalmitates, linoleates, linolenates and oleostearates of sucrose, glucose or methylglucose.

[0062] An example that may be mentioned is the product sold by the company Amerchol under the name A product sold by DO which is methyl glucose dioleate.

[0063] As examples of preferred ester oils, mention may be made of, for example, diisopropyl adipate, dioctyl adipate, 2-ethylhexyl hexanoate, ethyl laurate, cetyl octanoate, octyldodecyl octanoate, isodecyl neopentanoate, myristyl propionate, 2-ethylhexyl 2-ethylhexanoate, 2-ethylhexyl octanoate, 2-ethylhexyl octanoate / caprate, methyl palmitate, ethyl palmitate, isopropyl palmitate, dicaprylyl carbonate, isopropyl lauroyl sarcosinate, isononyl isononanoate, ethylhexyl palmitate, isohexyl laurate, hexyl laurate, isocetyl stearate, isopropyl isostearate, isopropyl myristate, isodecyl oleate, glyceryl tri(2-ethylhexanoate), pentaerythritol tetra(2-ethylhexanoate), 2-ethylhexyl succinate, diethyl sebacate, and mixtures thereof.

[0064] As examples of artificial triglycerides, there may be mentioned, for example, capryl caprylylglyceride, trimyristin, tripalmitin, trilinolenic acid, trilaurin, tricaprin, tricaprylin, tri(caprylic acid / caprylic acid)glyceride and tri(capric acid / caprylic acid / linolenic acid)glyceride.

[0065] As examples of silicone oils, there may be mentioned, for example, linear organopolysiloxanes such as dimethylpolysiloxane, methylphenylpolysiloxane, methylhydrogenpolysiloxane and the like; cyclic organopolysiloxanes such as cyclohexasiloxane, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane and the like; and mixtures thereof.

[0066] Preferably, the silicone oil is chosen from liquid polydialkylsiloxanes, in particular liquid polydimethylsiloxane (PDMS); and liquid polyorganosiloxanes comprising at least one aromatic group.

[0067] These silicone oils may also be organomodified.The organomodified silicones that can be used according to the invention are silicone oils as defined above and which contain in their structure one or more organofunctional groups linked via hydrocarbon-based groups.

[0068] Organopolysiloxanes are defined in more detail in Walter Noll, Chemistry and Technology of Silicones (1968) (Academic Press). They can be volatile or nonvolatile.

[0069] When the silicones are volatile, they are more particularly chosen from those having a boiling point between 60° C. and 260° C., and even more particularly from: (i) Cyclic polydialkylsiloxanes containing 3 to 7 silicon atoms and preferably 4 to 5 silicon atoms. These are for example those sold, inter alia, by Union Carbide under the name Volatile 7207 or by Rhodia under the name Octamethylcyclotetrasiloxane sold as 70045 V2; marketed by Union Carbide under the name Volatile 7158, by Rhodia under the name decamethylcyclopentasiloxane sold under the name Silsoft 70045 V5 by Momentive Performance Materials; and dodecamethylcyclopentasiloxane sold under the name Silsoft 1217 by Momentive Performance Materials; and mixtures thereof. Mention may also be made of, for example, cyclic copolymers of the dimethylsiloxane / methylalkylsiloxane type, such as Silicone sold by the company Union Carbide. FZ 3109, which has the following formula: in Mention may also be made of mixtures of cyclic polydialkylsiloxanes with organosilicon compounds, for example a mixture of octamethylcyclotetrasiloxane and tetrakis(trimethylsilyl)pentaerythritol (50 / 50) and a mixture of octamethylcyclotetrasiloxane and oxy-1,1′-bis(2,2,2′,2′,3,3′-hexa(trimethylsiloxy))neopentane; and (ii) a linear volatile polydialkylsiloxane containing 2 to 9 silicon atoms and having a carbonyl group of less than or equal to 5×10 -6 m 2 / s viscosity. An example is decamethyltetrasiloxane, sold in particular by the company Toray Silicone under the name SH 200. Silicones belonging to this class are also described in the article Volatile Silicone Fluids for Cosmetics published by Todd & Byers in Cosmetics and Toiletries (Volume 91, January 1976, pages 27-32). The viscosity of silicones is measured at 25° C. according to ASTM standard 445, Appendix C.

[0070] It is also possible to use nonvolatile polydialkylsiloxanes. These nonvolatile silicones are more particularly chosen from polydialkylsiloxanes, among which mention may mainly be made of polydimethylsiloxanes containing trimethylsilyl end groups.

[0071] Among these polydialkylsiloxanes, mention may be made in a non-limiting manner of the following commercial products: - 47 and 70 047 series sold by Rhodia Oil or Oil, for example oil 70 047V500 000; -Sold by Rhodia Series of oils; - Oils of the 200 series from Dow Corning, e.g. with a viscosity of 60 000 mm 2 / s DC 200; and -From General Electric Oils and certain oils from General Electric's SF series (SF 96, SF 18).

[0072] Mention may also be made of the polydimethylsiloxanes containing dimethylsilanol end groups known under the name dimethiconol (CTFA), for example the oils of the 48 series from the company Rhodia.

[0073] Among the silicones containing aryl groups, mention may be made of polydiarylsiloxanes, in particular polydiphenylsiloxanes and polyalkylarylsiloxanes, such as phenyl silicone oils.

[0074] The phenyl silicone oil can be selected from the phenyl silicones of the following formula: in R1 to R 10 Independently of each other, saturated or unsaturated linear, cyclic or branched C1-C 30 A hydrocarbon group, preferably based on C1-C 12a hydrocarbon group, and more preferably a C1-C6 hydrocarbon-based group, especially methyl, ethyl, propyl or butyl, and m, n, p and q are each independently an integer of 0-900 (inclusive), preferably 0-500 (inclusive), and more preferably 0-100 (inclusive), The constraint is that the sum n+m+q is an integer other than 0.

[0075] Examples which may be mentioned include the products sold under the following names: - 70 641 series from Rhodia Oil; -From Rhodia 70 Oils of the 633 and 763 series; - oil from Dow Corning Dow Corning 556 Cosmetic Grade Fluid; - Silicones from the PK series from Bayer, for example the product PK20; - Certain oils from General Electric's SF series, such as SF 1023, SF 1154, SF 1250 and SF1265.

[0076] As the phenyl silicone oil, phenyl trimethylsiloxane (in the above formula, R1 to R 10 is methyl; p, q and n = 0; m = 1).

[0077] The organomodified liquid silicones may contain in particular polyethyleneoxy and / or polypropyleneoxy groups. Mention may thus be made of silicone KF-6017 proposed by Shin-Etsu, and oils from the company Union Carbide. L722 and L77.

[0078] The hydrocarbon oil may be selected from: - linear or branched, optionally cyclic C6-C 16 Lower alkanes. Examples that may be mentioned include hexane, undecane, dodecane, tridecane and isoparaffins, such as isohexadecane, isododecane and isodecane; and - linear or branched hydrocarbons containing more than 16 carbon atoms, such as liquid paraffin, liquid petroleum jelly, polydecene and hydrogenated polyisobutene (e.g. ); and squalane.

[0079] As preferred examples of hydrocarbon oils, there can be mentioned, for example, linear hydrocarbons or branched hydrocarbons such as isohexadecane, isododecane, squalane; mineral oils such as liquid paraffin, paraffin, vaseline or petrolatum, naphthalene and the like; hydrogenated polyisobutene, isoeicosane, and decene / butene copolymers; and mixtures thereof.

[0080] The term "fatty" in fatty alcohol means that it contains a relatively large number of carbon atoms. Therefore, alcohols having 4 or more carbon atoms, preferably 6 or more carbon atoms, and more preferably 12 or more carbon atoms are included within the scope of fatty alcohol. Fatty alcohols can be saturated or unsaturated. Fatty alcohols can be linear or branched.

[0081] The fatty alcohol may have the structure R-OH, wherein R is selected from saturated and unsaturated linear and branched groups containing 4 to 40 carbon atoms, preferably 6 to 30 carbon atoms, and more preferably 12 to 20 carbon atoms. In at least one embodiment, R may be selected from C 12 -C 20 Alkyl and C 12 -C 20 R may or may not be substituted with at least one hydroxyl group.

[0082] As examples of fatty alcohols, mention may be made of lauryl alcohol, cetyl alcohol, stearyl alcohol, isostearyl alcohol, behenyl alcohol, undecyl alcohol, myristyl alcohol, octyldodecanol, hexyldecanol, oleyl alcohol, linoleyl alcohol, palmitoleyl alcohol, arachidonic acid, erucyl alcohol, and mixtures thereof.

[0083] Preferably, the fatty alcohol is a saturated fatty alcohol.

[0084] Therefore, the fatty alcohol can be selected from linear or branched saturated or unsaturated C6-C 30 Alcohols, preferably linear or branched saturated C6-C 30 Alcohols, and more preferably linear or branched saturated C 12 -C 20 alcohol.

[0085] The term "saturated fatty alcohol" herein refers to an alcohol having a long aliphatic saturated carbon chain. Preferably, the saturated fatty alcohol is selected from any linear or branched saturated C6-C 30 Fatty alcohol. Linear or branched saturated C6-C 30 Among the fatty alcohols, linear or branched saturated C 12 -C 20 Fatty alcohols. Any linear or branched saturated C 16 -C 20 Fatty alcohols. Even more preferably, branched C 16 -C 20 Fatty alcohol.

[0086] As examples of saturated fatty alcohols, mention may be made of lauryl alcohol, cetyl alcohol, stearyl alcohol, isostearyl alcohol, behenyl alcohol, undecyl alcohol, myristyl alcohol, octyldodecanol, hexyldecanol, and mixtures thereof. In one embodiment, cetyl alcohol, stearyl alcohol, octyldodecanol, hexyldecanol, or mixtures thereof (e.g., cetearyl alcohol) and behenyl alcohol may be used as saturated fatty alcohols.

[0087] According to at least one embodiment, the fatty alcohol used in the composition according to the invention is preferably chosen from cetyl alcohol, octyldodecanol, hexyldecanol, and mixtures thereof.

[0088] It is also preferred that (a) the oil is selected from oils having a molecular weight below 600 g / mol.

[0089] Preferably, (a) oil has a low molecular weight, for example less than 600 g / mol, selected from oils having one or more short hydrocarbon chains (C1-C 12 ) ester oils (e.g. isopropyl lauroyl sarcosinate, isopropyl myristate, isopropyl palmitate, isononyl isononanoate and ethylhexyl palmitate), silicone oils (e.g. volatile silicones such as cyclohexasiloxane), hydrocarbon oils (e.g. isododecane, isohexadecane and squalane); branched and / or unsaturated fatty alcohols (C 12 -C 30 ) type oils, such as octyldodecanol and oleyl alcohol; and ether oils, such as dicaprylyl ether.

[0090] Hereinafter, preferred embodiments of (a) oil are described.

[0091] Preferably, under the following conditions, (a) the oil is selected from (i) fatty alcohols, (ii) fatty acids, (iii) monocarboxylic acid monoesters, (iv) dicarboxylic acid diesters, (v) N-acylamino acid esters and (vi) alkyl lactates: - (i) fatty alcohols and (ii) fatty acids contain branched alkyl groups, or straight or branched alkenyl groups, each of which has 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, - (iii) the monocarboxylic acid monoester contains a branched alkyl group, or a straight or branched alkenyl group, each of which has 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, - (iv) the dicarboxylic acid diester comprises at least one (preferably two) branched alkyl groups having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms, and an alkenyl group having 6 to 18 carbon atoms, preferably 6 to 14 carbon atoms, and more preferably 6 to 10 carbon atoms, -(v) the N-acylamino acid ester comprises a branched chain alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms, and a straight chain or branched chain acyl group having 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, and - (vi) The alkyl lactate contains a linear or branched alkyl group, or a linear or branched alkenyl group, each of which has 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms.

[0092] In the present specification, "alkyl" refers to a linear or branched monovalent saturated aliphatic hydrocarbon group.

[0093] As the straight-chain alkyl group having 4 to 30 carbon atoms, there can be mentioned, for example, n-butyl, n-pentyl, n-hexyl, n-heptyl, n-octyl, n-nonyl, n-decyl, n-undecyl, n-dodecyl, n-tridecyl, n-tetradecyl, n-pentadecyl, n-hexadecyl, n-heptadecyl, n-octadecyl, n-nonadecyl and n-eicosyl groups.

[0094] As the branched alkyl group having 4 to 30 carbon atoms, there can be mentioned, for example, an isobutyl group, a sec-butyl group, a tert-butyl group, an isopentyl group, a neopentyl group, an isohexyl group, a neohexyl group, an isoheptyl group, a neoheptyl group, an isooctyl group, an isononyl group, an isodecyl group, an isoundecyl group, an isoundecyl group, an isotridecyl group, an isotetradecyl group, an isopentadecyl group, an isohexadecyl group, an isoheptadecyl group, an isooctadecyl group, an isonadecyl group and an isoeicosyl group.

[0095] As the branched alkyl group having 3 to 10 carbon atoms, there can be mentioned, for example, isopropyl, isobutyl, sec-butyl, tert-butyl, isopentyl, neopentyl, isohexyl, neohexyl, isoheptyl, neoheptyl, isooctyl, isononyl and isodecyl.

[0096] In the present specification, "alkenyl group" refers to a linear or branched monovalent unsaturated aliphatic hydrocarbon group having at least one carbon-carbon double bond.

[0097] As the straight-chain alkenyl group having 4 to 30 carbon atoms, there can be mentioned, for example, butenyl, pentenyl, hexenyl, heptenyl, heptadienyl, heptatrienyl, octenyl, octadienyl, octatrienyl, nonenyl, nonadienyl, nonatrienyl, decenyl, decadienyl, decatrienyl, undecenyl, undecadienyl, undecadienyl, dodecenyl, dodecadienyl, dodecatrienyl, tridecenyl, tridecenyl, tridecadi ... yl, tridecanyl, tetradecanyl, tetradecadienyl, tetradecadienyl, tetradecadienyl, tetradecadienyl, pentadecenyl, pentadecadienyl, pentadecadienyl, pentadecatrienyl, hexadecenyl, hexadecadienyl, hexadecadienyl, hexadecadienyl, heptadecatrienyl, heptadecenyl, heptadecadienyl, heptadecatrienyl, octadecenyl, octadecadienyl, octadecatrienyl, nonadecenyl, nonadecadienyl, nonadecatrienyl and eicosenyl.

[0098] As the branched alkenyl group having 4 to 30 carbon atoms, there can be mentioned, for example, an isobutenyl group, a sec-butenyl group, an isopentenyl group, an isohexenyl group, an isoheptenyl group, an isooctenyl group, an isononenyl group, an isodecenyl group, an isodecadienyl group, an isodecatrienyl group, an isoundecenyl group, an isoundecadienyl group, an isoundectrienyl group, an isododecenyl group, an isododecatrienyl group, an isotridecenyl group, an isotridecadienyl group, an isotridecatrienyl group, an isotetradecenyl group isodecadienyl, isodecadienyl, isodecadienyl, isodecadienyl, isodecadienyl, isodecadienyl, isopentadecenyl, isopentadecadienyl, isopentadectrienyl, isohexadecenyl, isohexadecadienyl, isohexadecatrien ...

[0099] In the present specification, "acyl group" refers to an R-CO- group, wherein R represents a linear or branched monovalent saturated aliphatic hydrocarbon group (alkyl group).

[0100] As the straight-chain or branched acyl group having 4 to 30 carbon atoms, there can be mentioned, for example, butyryl, isobutyryl, sec-butyryl, tert-butyryl, n-valeryl, isovaleryl, pivaloyl, n-hexanoyl, isohexanoyl, neohexanoyl, n-heptanoyl, isoheptanoyl, neoheptanoyl, n-octanoyl, isooctanoyl, n-nonanoyl, isononanoyl, n-decanoyl, isodecanoyl, n-undecanoyl, isoundecanoyl, n-dodecanoyl (lauroyl), isododecanoyl, n-tridecanoyl, isotridecanoyl (isotridecanoyl), and n-decanoyl. group), n-tetradecanoyl (myristoyl), isotetradecanoyl, n-pentadecanoyl, isopentadecanoyl, n-hexadecanoyl (palmitoyl), isohexadecanoyl, n-heptadecanoyl, isohexadecanoyl, n-octadecanoyl (stearoyl), isoctadecanoyl, n-nonadecanoyl, isonadecanoyl, n-eicosanoyl and isoeicosanoyl.

[0101] (i) The fatty alcohol can be represented by the following general formula (1): R 1 -OH(1) in R 1 represents a branched alkyl group, or a straight or branched alkenyl group, each having 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms.

[0102] As examples of the branched alkyl group and the straight or branched alkenyl group each having 4 to 30 carbon atoms, those exemplified above can be mentioned.

[0103] As the (i) fatty alcohol represented by the formula (1), there may be mentioned, for example, 2-ethylhexanol, palmitoleyl alcohol, isostearyl alcohol, elaidic alcohol, oleyl alcohol, linolenyl alcohol, ricinoleyl alcohol, erucyl alcohol, and a mixture thereof.

[0104] Preferably, (i) the fatty alcohol is selected from isostearyl alcohol, oleyl alcohol, and mixtures thereof.

[0105] (ii) The fatty acid can be represented by the following general formula (2): R1-COOH (2) in R 1 represents a branched alkyl group, or a straight or branched alkenyl group, each having 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms.

[0106] As examples of the branched alkyl group and the straight or branched alkenyl group each having 4 to 30 carbon atoms, those exemplified above can be mentioned.

[0107] As the (ii) fatty acid represented by formula (2), there can be mentioned, for example, isocaproic acid, isononanoic acid, crotonic acid, isolauric acid, myristic acid, isopalmitic acid, palmitoleic acid, isostearic acid, elaidic acid, oleic acid, linoleic acid, linolenic acid, arachidonic acid, eicosapentaenoic acid, tetracosapentaenoic acid, docosahexaenoic acid, nervonic acid, and mixtures thereof.

[0108] Preferably, the (ii) fatty acid is selected from isostearic acid, oleic acid, and mixtures thereof.

[0109] (iii) The monocarboxylic acid monoester can be represented by the following general formula (3): R 2 -COO-R 3 (3) in R 2 represents a branched alkyl group, or a straight or branched alkenyl group, each of which has 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, and R 3 represents a branched alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms.

[0110] As examples of the branched alkyl group and the straight or branched alkenyl group each having 4 to 30 carbon atoms, those exemplified above can be mentioned.

[0111] As examples of the branched alkyl group having 3 to 10 carbon atoms, those exemplified above can be mentioned.

[0112] As the (iii) monocarboxylic acid monoester represented by formula (3), there can be mentioned, for example, isopropyl palmitate, isopropyl myristate, isocetyl stearate, 2-ethylhexyl isononanoate, isononyl isononanoate, isodecyl neopentanoate, isostearyl neopentanoate, and mixtures thereof.

[0113] Preferably, (iii) the monocarboxylic acid monoester is isopropyl isostearate.

[0114] (iv) The dicarboxylic acid diester can be represented by the following general formula (4): R 2 -OC(=O)-R 4 -C(=O)OR 3 (4) in R 2 and R 3 independently represents a branched alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms, and R 4 represents a straight or branched alkylene group having 6 to 18 carbon atoms, preferably 6 to 14 carbon atoms, and more preferably 6 to 10 carbon atoms.

[0115] As examples of the branched alkyl group having 3 to 10 carbon atoms, those exemplified above can be mentioned.

[0116] As examples of the linear or branched alkylene group having 2 to 10 carbon atoms, there may be mentioned, for example, ethylene, propylene, butylene, pentylene, hexylene, heptylene, octylene, nonylene and decylene.

[0117] Preferably, the (iv) dicarboxylic acid diester is selected from diisopropyl adipate, diisopropyl sebacate, and mixtures thereof.

[0118] (v) N-acyl amino acid esters can be represented by the following general formula (5): R 2 -N(R 5 )-CH(R 6 )-(CH2) n -COO-R 3 (5) in R 2 represents a straight-chain or branched acyl group having 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, R 3 represents a branched alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms, R 5represents a hydrogen atom or a straight-chain or branched alkyl group having 1 to 4 carbon atoms, R 6 represents a hydrogen atom or a straight or branched alkyl group having 1 to 4 carbon atoms which may be substituted with a hydroxyl group or a phenyl group, and n represents an integer from 0 to 2.

[0119] As examples of the linear or branched acyl group having 4 to 30 carbon atoms, those exemplified above can be mentioned.

[0120] As examples of the branched alkyl group having 3 to 10 carbon atoms, those exemplified above can be mentioned.

[0121] As examples of the straight-chain or branched alkyl group having 1 to 4 carbon atoms, there may be mentioned a methyl group, an ethyl group, a propyl group, an isopropyl group, an n-butyl group, an isobutyl group, a sec-butyl group and a tert-butyl group.

[0122] As the (v) N-acylamino acid ester represented by the formula (5), there can be mentioned, for example, N-octanoylsarcosine isopropyl, N-decanoylsarcosine isopropyl, N-lauroylsarcosine isopropyl, N-coconut oil fatty acid acylsarcosine isopropyl (N-cocoylsarcosine isopropyl), N-myristoylsarcosine isopropyl, N-palmitoylsarcosine isopropyl, N-stearoylsarcosine isopropyl, N-octanoylsarcosine isobutyl, N-decanoylsarcosine isobutyl, N-lauroylsarcosine isobutyl, N-coconut oil fatty acid acylsarcosine isopropyl (N-cocoylsarcosine isopropyl), N-myristoylsarcosine isopropyl, N-palmitoylsarcosine isopropyl, N-stearoylsarcosine isopropyl, N-octanoylsarcosine isobutyl, N-decanoylsarcosine isobutyl, N-lauroylsarcosine isobutyl, N-octanoylglycine isopropyl, N-decanoylglycine isopropyl, N-lauroylsarcosine isobutyl isopropyl glycine, isopropyl N-coconut oil fatty acid acyl glycine (isopropyl N-cocoyl glycine), isopropyl N-myristoyl glycine, isopropyl N-palmitoyl glycine, isopropyl N-stearoyl glycine, isopropyl N-capryloyl alanine, isopropyl N-decanoyl alanine, isopropyl N-lauroyl alanine, isopropyl N-coconut oil fatty acid acyl alanine (isopropyl N-cocoyl alanine), isopropyl N-myristoyl alanine, isopropyl N-palmitoyl alanine, isopropyl N-stearoyl alanine, isopropyl N-lauroyl-β-alanine, isopropyl N-lauroyl-N-methyl-β-alanine, isopropyl N-coconut oil fatty acid acyl-N-methyl-β-alanine (isopropyl N-cocoyl-N-methyl-β-alanine), and the like.

[0123] Preferably, (v) the N-acylamino acid ester is isopropyl lauroyl sarcosinate. As isopropyl lauroyl sarcosinate, for example, Products like SL-205.

[0124] (vi) Alkyl lactate can be represented by the following general formula (6): CH3-C(OH)-COO-R 7 (6) in R 7 represents a straight chain or branched chain alkyl group, or a straight chain or branched chain alkenyl group, each of which has 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms.

[0125] As examples of the straight-chain or branched-chain alkyl group, or the straight-chain or branched-chain alkenyl group each having 4 to 30 carbon atoms, there can be mentioned those exemplified above.

[0126] As examples of (vi) alkyl lactates represented by formula (6), there can be mentioned, for example, decyl lactate, octyl lactate, lauryl lactate, myristyl lactate, palmityl lactate, stearyl lactate, isostearyl lactate, oleyl lactate and linoleyl lactate.

[0127] Preferably, the (vi) alkyl lactate is selected from lauryl lactate, isostearyl lactate, and mixtures thereof.

[0128] The amount of (a) oil in the composition according to the present invention may be 0.5% by weight or more, preferably 1% by weight or more, and more preferably 2% by weight or more, relative to the total weight of the composition.

[0129] On the other hand, the amount of (a) oil in the composition according to the present invention may be 25 wt% or less, preferably 20 wt% or less, and more preferably 15 wt% or less, relative to the total weight of the composition.

[0130] Thus, the amount of (a) oil in the composition according to the invention may be from 0.5% to 25% by weight, preferably from 1% to 20% by weight and more preferably from 2% to 15% by weight relative to the total weight of the composition.

[0131] [Diols] The composition according to the invention comprises at least one (b) diol having at least one carbon chain containing 3 or more carbon atoms. Two or more (b) diols having at least one carbon chain containing 3 or more carbon atoms may be used.

[0132] The term "diol" herein refers to a compound having two alcohol functional groups. In other words, a diol is an alcohol having two hydroxyl groups.

[0133] The number of carbon atoms in the carbon chain may be 10 or less, preferably 8 or less, and more preferably 6 or less. It may be even more preferred that the number of carbon atoms in the carbon chain is 5 or 6.

[0134] The carbon chain containing 3 or more carbon atoms in component (b) may be linear or branched. The carbon chain may not be interrupted by heteroatoms (e.g., oxygen atoms, sulfur atoms, and nitrogen atoms). Thus, the carbon chain may contain continuous carbon atoms.

[0135] It is preferred that the number of carbon chains containing 3 or more carbon atoms in component (b) is 1 or 2.

[0136] The total number of carbon atoms in ingredient (b) may be 5 or more. The total number of carbon atoms in ingredient (b) may be 10 or less, preferably 8 or less, and more preferably 6 or less. It may be even more preferred that the total number of carbon atoms in ingredient (b) is 5 or 6.

[0137] (b) The diol having at least one carbon chain containing 3 or more (preferably 8 or less, and more preferably 6 or less) carbon atoms may have a divalent straight or branched hydrocarbon group. The divalent straight or branched hydrocarbon group that may be present in component (b) may be saturated or unsaturated. Preferably, (b) the diol having at least one carbon chain containing 3 or more carbon atoms contains a divalent straight or branched saturated hydrocarbon group, and more preferably a straight or branched alkylene group, such as propylene, butylene, pentylene and hexylene.

[0138] (b) The diol having at least one carbon chain containing 3 or more carbon atoms may have a linear, branched or cyclic molecular structure as long as it has a carbon chain containing 3 or more carbon atoms.

[0139] (b) The diol having at least one carbon chain containing 3 or more carbon atoms may be a C 3-10 Diol, preferably C 4-8 diols, and more preferably C 5-6 Diols.

[0140] Preferably, (b) the diol having at least one carbon chain containing 3 or more carbon atoms is selected from propylene glycol, dipropylene glycol, polypropylene glycol, butylene glycol, dibutylene glycol, polybutylene glycol, pentylene glycol, dipentylene glycol, hexylene glycol, dihexylene glycol, and mixtures thereof.

[0141] More preferably, (b) the diol having at least one carbon chain containing 3 or more carbon atoms is selected from propylene glycol, dipropylene glycol, butanediol, pentanediol, hexanediol, and mixtures thereof. Most preferably, pentanediol.

[0142] The amount of (b) diol having at least one carbon chain containing 3 or more carbon atoms in the composition according to the present invention may be 20 wt % or more, preferably 25 wt % or more, and more preferably 30 wt % or more, relative to the total weight of the composition.

[0143] On the other hand, the amount of (b) diol having at least one carbon chain containing 3 or more carbon atoms in the composition according to the present invention can be 60 wt % or less, preferably 55 wt % or less, and more preferably 50 wt % or less, relative to the total weight of the composition.

[0144] Thus, the amount of (b) diol having at least one carbon chain containing 3 or more carbon atoms in the composition according to the invention may be 20% to 60% by weight, preferably 25% to 55% by weight and more preferably 30% to 50% by weight relative to the total weight of the composition.

[0145] [Diol / oil weight ratio] The weight ratio of the amount of (b) diol having at least one carbon chain containing 3 or more carbon atoms to the amount of (a) oil may be 4 or more, preferably 5 or more, and more preferably 6 or more.

[0146] On the other hand, the weight ratio of the amount of (b) diol having at least one carbon chain containing 3 or more carbon atoms to the amount of (a) oil may be 20 or less, preferably 15 or less, and more preferably 10 or less.

[0147] Therefore, the weight ratio of the amount of (b) diol having at least one carbon chain containing 3 or more carbon atoms to the amount of (a) oil may be 4-20, preferably 5-15, and more preferably 6-10.

[0148] [Skin Care Actives] In one embodiment, the composition according to the invention comprises (c1) at least one skin care active ingredient. A single type of (c1) skin care active ingredient may be used, but two or more different types of (c1) skin care active ingredients may be used in combination.

[0149] It is preferred that the (c1) skin care active ingredient has a logP value of 4 or less, more preferably in the range of -4.5 to 4.0, and even more preferably -4.0 to 3.5.

[0150] The log P value is the value of the logarithm to base 10 for the apparent octan-1-ol / water partition coefficient. The log P value is known and is determined by a standard test for determining the concentration of the (c1) compound in octan-1-ol and water. The log P can be calculated according to the method described in the article Atom / Fragment contribution method for estimating octanol-water partition coefficients by Meylan and Howard, J. Pharm. Sci., 84: 83-92, 1995. The value can also be calculated using numerous commercially available software packages that determine log P as a function of molecular structure. By way of example, the Epiwin software from the United States Environmental Agency may be mentioned.

[0151] The values ​​can be calculated in particular using the ACD (Advanced Chemistry Development) Solaris software V4.67; they can also be obtained from Exploring QSAR: hydrophobic, electronic and steric constants (ACS Professional Reference Book, 1995). There is also an Internet website that provides estimated values ​​(address: http: / / esc.syrres.com / interkow / kowdemo.htm).

[0152] (c1) The skin care active ingredient may be in the form of a salt. (c1) Salts of the skin care active ingredient include conventional non-toxic salts of the compound, such as those formed from acids or bases.

[0153] Preferably, the (c1) skin care active ingredient is a skin care cosmetic active ingredient, and more preferably a skin whitening ingredient or a skin anti-aging ingredient, such as a skin anti-wrinkle ingredient.

[0154] As (c1) skin care active ingredients, mention may be made of vitamin B3 and derivatives.

[0155] Vitamin B3, also known as vitamin PP, is a compound having the following formula (I): Wherein R can be -CONH2 (nicotinamide), -COOH (nicotinic acid or nicotinic acid), or CH2OH (nicotinyl alcohol), -CO-NH-CH2-COOH (nicotinuric acid) or -CO-NH-OH (nicotinyl hydroxamic acid). Nicotinamide is preferred.

[0156] Vitamin B3 derivatives that may be mentioned include, for example, nicotinic acid esters, such as tocopheryl nicotinate, amides derived from nicotinamide by substitution of the hydrogen group of -CONH2, products from reactions with carboxylic acids and amino acids, esters of nicotinic alcohol with carboxylic acids, such as acetic acid, salicylic acid, glycolic acid or palmitic acid.

[0157] The following derivatives may also be mentioned: 2-chloronicotinamide, 6-methylnicotinamide, 6-aminonicotinamide, N-methylnicotinamide, N,N-dimethylnicotinamide, N-(hydroxymethyl)nicotinamide, quinolinic acid imide, nicotinanilide, N-benzylnicotinamide, N-ethylnicotinamide, nifenazone, nicotinaldehyde, isonicotinic acid, methylisonicotinic acid, thionicotinamide, nyalamid, 2-mercaptonicotinic acid, nicotinamide and nyprazine, methyl nicotinate and sodium nicotinate.

[0158] Other vitamin B3 derivatives that may be mentioned include its inorganic salts, for example chlorides, bromides, iodides or carbonates; and its organic salts, for example salts obtained by reaction with carboxylic acids, such as acetates, salicylates, glycolates, lactates, malates, citrates, mandelates, tartrates, etc.

[0159] As (c1) skin care active ingredients, there may be mentioned ascorbic acid and its derivatives.

[0160] Ascorbic acid is usually in the L form because it is usually extracted from natural products.

[0161] Since its chemical structure (α-ketolactone) makes it very sensitive to certain environmental parameters such as light, heat and aqueous media, it can be advantageous to use ascorbic acid in the form of derivatives or analogs selected from, for example, sugar esters of ascorbic acid or metal salts, alkali metal salts, esters and sugars of phosphoascorbic acid.

[0162] Sugar esters of ascorbic acid that can be used in the present invention are in particular glycosyl derivatives, mannosyl derivatives, fructosyl derivatives, fucosyl derivatives, galactosyl derivatives, N-acetylglucosamine derivatives and N-acetylmuramic acid derivatives of ascorbic acid, and mixtures thereof, and more particularly ascorbyl glucosides, such as ascorbic acid-2 glucoside, 2-O-α-D-pyranosyl glucoside L-ascorbic acid or 6-O-β-D-pyranosyl galactosyl L-ascorbic acid. The latter compounds and their preparation methods are particularly described in documents EP-A-0487404, EP-A-0425066 and JP 05213736.

[0163] As for the metal salt of phosphoascorbic acid, it may be selected from alkali metal salts of ascorbyl phosphate, and in particular sodium ascorbyl phosphate, alkaline earth metal salts of ascorbyl phosphate and transition metal salts of ascorbyl phosphate.

[0164] It is also possible to use ascorbic acid precursors, such as active agent amides and active agent sugar derivatives, which involve proteases or peptidases and glycosidases, respectively, as enzymes that release ascorbic acid in situ. Such compounds are described in patent EP 0 667145.

[0165] The active agent sugar derivatives are particularly selected from C3-C6 sugar derivatives. They are particularly selected from glucosyl derivatives, mannosyl derivatives, fructosyl derivatives, fucosyl derivatives, N-acetylglucosamine derivatives, galactosyl derivatives and N-acetylgalactosamine derivatives, N-acetylmuramic acid derivatives and sialic acid derivatives, and mixtures thereof.

[0166] The second ascorbic acid precursor can be selected from derivatives hydrolyzed by other enzymes, such as derivatives hydrolyzed by esterases, phosphatases, sulfatases, etc. According to the present invention, the second active agent precursor can be selected from, for example, phosphates; sulfates; palmitates; acetates; propionates; ferulates; and generally active agent alkyl esters or acyl esters; acyl ethers or alkyl ethers. Acyl and alkyl groups contain in particular 1 to 30 carbon atoms. As skin care active ingredients, 3-O-ethyl ascorbic acid can be mentioned.

[0167] In particular, the second precursor may be an ester resulting from reaction with an inorganic acid, such as a sulfate or phosphate ester for reaction with a sulfatase or phosphatase upon contact with the skin, and the second precursor may be an acyl ester or alkyl ester for reaction with a specific skin esterase, resulting from reaction with an organic acid such as palmitic acid, acetic acid, propionic acid, nicotinic acid, 1,2,3-propanetricarboxylic acid or ferulic acid.

[0168] Other derivatives are described, for example, in patent EP 1 430883.

[0169] Ascorbic acid analogs are more particularly salts thereof, in particular alkali metal salts, such as sodium ascorbate; esters thereof, such as in particular acetates, propionates or palmitates thereof; or sugars thereof, such as in particular glycosyl ascorbic acids.

[0170] As (c1) skin care active ingredients, resorcinol derivatives may be mentioned.

[0171] The resorcinol derivative may preferably be a 4-substituted derivative, such as 4-alkylresorcinol, more preferably phenethylresorcinol, 4-n-butylresorcinol and 4-(tetrahydro-2H-pyran-4-yl)benzene-1,3-diol, and especially phenethylresorcinol due to its whitening effect. Phenethylresorcinol is also known as 4-(1-phenylethyl)-1,3-benzene and is represented by the following chemical formula. Phenethylresorcinol is available from, for example, Symrise Corp (product name: ).

[0172] As other examples of resorcinol derivatives, mention may be made of: 2-methylresorcinol, 5-methylresorcinol, 4-methylresorcinol, 4-ethylresorcinol, 2,5-dimethylresorcinol, 4,5-dimethylresorcinol, 2,4-dimethyl-1,3-benzene, 3,5-dihydroxybenzylamine, 5-methoxyresorcinol, 3,5-dihydroxybenzyl alcohol, 2-methoxyresorcinol, 4-methoxyresorcinol, 3,5-dihydroxytoluene monohydrate, 4-chlororesorcinol, 2-chlororesorcinol, 2′,4′-dihydroxy Acetophenone, 3',5'-dihydroxyacetophenone, 2,6-dihydroxy-4-methylbenzaldehyde, 4-propylresorcinol, 2,4-dihydroxy-1,3,5-trimethylbenzene, 3,5-dihydroxybenzamide, 2,6-dihydroxybenzamide, 2,4-dihydroxybenzamide, 2,4-dihydroxybenzoic acid, 2,6-dihydroxybenzoic acid, 3,5-dihydroxybenzoic acid, 2,6-dihydroxy-4-methylbenzyl alcohol, 3,5-dihydroxyanisole hydrate, 4-aminoresorcinol hydrochloride, 2-aminoresorcinol hydrochloride, 5- Aminobenzene-1,3-diphenol hydrochloride, 2',4'-dihydroxypropiophenone, 2',4'-dihydroxy-3'-methylacetophenone, (2,4-dihydroxyphenyl)acetone, (3,5-dihydroxyphenyl)acetone, 2,6-dihydroxy-4'-methylacetophenone, 4-n-butylresorcinol, 2,4-diethyl-1,3-benzene, 3,5-dihydroxy-4-methylbenzoic acid, 2,6-dihydroxy-4-methylbenzoic acid, 2,4-dihydroxy-6-methylbenzoic acid, 3,5-dihydroxyphenylacetic acid, 2-ethyl-5-methoxy phenyl-1,3-diol, 4-amino-3,5-dihydroxybenzoic acid, 3,5-dihydroxyacetophenone monohydrate, 3,5-dihydroxybenzylamine hydrochloride, 4,6-dichlororesorcinol, 2′,4′-dihydroxy-3′-methylpropiophenone, 1-(3-ethyl-2,6-dihydroxyphenyl)ethan-1-one, 2′,6′-dihydroxy-4′-methoxyacetophenone, 1-(2,6-dihydroxy-3-methoxyphenyl)ethan-1-one, 3(2,4-dihydroxyphenylpropionic acid and 2,4-dihydroxy-3,6-dimethylbenzoic acid.

[0173] As (c1) skin care active ingredients, there may be mentioned C-glycoside derivatives.

[0174] The C-glycoside derivatives that may be present in the composition according to the invention are chosen from the following compounds of the general formula (II), and also their cosmetically acceptable salts, their solvates (eg hydrates), and their optical isomers: in: R represents unsubstituted straight-chain C1-C4 alkyl and in particular C1-C2 alkyl, especially methyl; S represents a monosaccharide selected from D-glucose, D-xylose, N-acetyl-D-glucosamine and L-fucose, and in particular D-xylose; X represents a group selected from -CO-, -CH(OH)- and -CH(NH2)-, and is preferably a -CH(OH)- group.

[0175] As non-limiting illustration of C-glycoside derivatives more particularly suitable for use in the present invention, mention may be made in particular of the following derivatives, and also of their cosmetically acceptable salts, their solvates (for example hydrates), and their optical isomers: C-β-D-xylopyranoside-n-propan-2-one; C-α-D-xylopyranosyl-n-propan-2-one; C-β-D-xylopyranosyl-2-hydroxypropane; C-α-D-xylopyranosyl-2-hydroxypropane; 1-(C-β-D-glucopyranosyl)-2-hydroxypropane; 1-(C-α-D-glucopyranosyl)-2-hydroxypropane; 1-(C-β-D-glucopyranosyl)-2-aminopropane; 1-(C-α-D-glucopyranosyl)-2-aminopropane; 3′-(acetamido-C-β-D-glucopyranosyl)propan-2′-one; 3′-(acetamido-C-α-D-glucopyranosyl)propan-2′-one; 1-(Acetamido-C-β-D-glucopyranosyl)-2-hydroxypropane; 1-(Acetamido-C-β-D-glucopyranosyl)-2-aminopropane.

[0176] According to a particular embodiment, C-β-D-xylopyranosyl-2-hydroxypropane or C-α-D-xylopyranosyl-2-hydroxypropane, and still better C-β-D-xylopyranosyl-2-hydroxypropane, can advantageously be used for the preparation of the composition according to the invention.

[0177] According to a particular embodiment, the C-glycoside derivative suitable for use in the present invention may advantageously be hydroxypropyltetrahydropyrantriol, also known as C-β-D-xylopyranoside-2-hydroxypropane, in particular as a 30% by weight solution in a water / propylene glycol mixture (60 / 40), available from Chimex under the name Mexoryl According to one embodiment, the C-glycoside derivative is in the form of a solution, wherein it is present in an amount of 30% by weight relative to the total weight of the solution, the remainder being a mixture of water and propylene glycol.

[0178] Salts of C-glycoside derivatives suitable for use in the present invention may include conventional physiologically acceptable salts of these compounds, such as those formed from organic or inorganic acids. Examples that may be mentioned include salts of inorganic acids, such as sulfuric acid, hydrochloric acid, hydrobromic acid, hydroiodic acid, phosphoric acid and boric acid. Salts of organic acids may also be mentioned, and the organic acid may contain one or more carboxylic acid groups, sulfonic acid groups or phosphonic acid groups. They may be linear, branched or cyclic aliphatic acids; or aromatic acids. These acids may also contain one or more heteroatoms selected from O and N (e.g. in the form of hydroxyl groups). Propionic acid, acetic acid, terephthalic acid, citric acid and tartaric acid may be mentioned in particular.

[0179] Acceptable solvents for the compounds described above include conventional solvates, such as those formed during the final steps of the preparation of the compounds due to the presence of solvents. Examples that may be mentioned include solvates due to the presence of water or linear or branched alcohols (such as ethanol or isopropanol).

[0180] The C-glycoside derivatives suitable for use in the present invention can be obtained in particular via the synthesis method described in document WO 02 / 051 828, the content of which is incorporated herein by reference.

[0181] As (c1) skin care active ingredients, salicylic acid and its derivatives may be mentioned. Salicylic acid derivatives may be represented by formula (iii): in The radical R represents a linear, branched or cyclic saturated aliphatic chain containing 2 to 22 carbon atoms; an unsaturated chain containing 2 to 22 carbon atoms, which contains one or more conjugated double bonds; an aromatic nucleus directly linked to the carbonyl group or linked to the carbonyl group via a saturated or unsaturated aliphatic chain containing 2 to 7 carbon atoms; the radical may be substituted by one or more substituents, which may be identical or different, selected from (a) halogen atoms, (b) trifluoromethyl, (c) hydroxyl groups in free form or esterified with acids containing 1 to 6 carbon atoms, or (d) carboxyl functions in free form or esterified with lower alcohols containing 1 to 6 carbon atoms; and R' is a hydroxyl group. The salicylic acid derivative may be in the form of a salt derived from an inorganic base or an organic base.

[0182] As (c1) skin care active ingredients, there may be mentioned tranexamic acid and its derivatives, such as esters and amides of tranexamic acid.

[0183] As examples of the tranexamic acid derivative, there can be mentioned a dimer of tranexamic acid (e.g., trans-4-(trans-aminomethylcyclohexanecarbonyl)aminomethylcyclohexanecarboxylic acid hydrochloride), an ester of tranexamic acid with hydroquinone (e.g., trans-4-aminomethylcyclohexanecarboxylic acid 4′-hydroxyphenyl ester), an ester of tranexamic acid with gentisic acid (e.g., 2-(trans-4-aminomethylcyclohexanecarbonyloxy)-5-hydroxybenzoic acid and a salt thereof), an amide of tranexamic acid (e.g., trans-4-aminomethylcyclohexanecarboxylic acid methylamide and a salt thereof, trans-4-(p-methoxybenzoyl)aminomethylcyclohexanecarboxylic acid and a salt thereof, and trans-4-guanidinomethylcyclohexanecarboxylic acid and a salt thereof), and the like.

[0184] Even more preferably, the (c1) skin care active ingredient is selected from ascorbyl glucoside, 3-O-ethyl ascorbic acid, tranexamic acid, hydroxypropyl tetrahydropyrantriol, niacinamide, salicylic acid, phenethylresorcinol, and mixtures thereof.

[0185] The amount of (c1) skin care active ingredient in the composition according to the present invention may be 0.01 wt% or more, preferably 0.05 wt% or more, and more preferably 0.1 wt% or more, relative to the total weight of the composition.

[0186] On the other hand, the amount of (c1) skin care active ingredient in the composition according to the present invention may be 25 wt% or less, preferably 20 wt% or less, and more preferably 15 wt% or less, relative to the total weight of the composition.

[0187] Thus, the amount of (c1) skin care active ingredient in the composition according to the invention may range from 0.01% to 25% by weight, preferably from 0.05% to 20% by weight, more preferably from 0.1% to 15% by weight, relative to the total weight of the composition.

[0188] [Cellulose compounds] In another embodiment, the composition according to the invention comprises (c2) at least one cellulose compound. Two or more (c2) cellulose compounds may be used.

[0189] The (c2) cellulose compound may be an anionic polymer, a cationic polymer, an amphoteric polymer or a nonionic polymer.

[0190] According to the present invention, the term "cellulose" compound means any polysaccharide compound having in its structure a sequence of glucose residues linked together via β-1,4 bonds, including unsubstituted cellulose, as well as anionic cellulose derivatives, cationic cellulose derivatives, amphoteric cellulose derivatives and nonionic cellulose derivatives.

[0191] Thus, the (c2) cellulose compound may be selected, for example, from unsubstituted cellulose (including in the form of microcrystalline), and cellulose ethers, cellulose esters, cellulose ester ethers and mixtures thereof. Among the cellulose esters, there may be mentioned inorganic esters of cellulose (cellulose nitrate, cellulose sulfate, cellulose phosphate, etc.), organic cellulose esters (cellulose monoacetate, cellulose triacetate, cellulose amidopropionate, cellulose acetate butyrate, cellulose acetate propionate and cellulose acetate trimellitate, etc.), and mixed organic / inorganic esters of cellulose, such as cellulose acetate butyrate sulfate and cellulose acetate propionate sulfate. Among the cellulose ester ethers, there may be mentioned hydroxypropyl methylcellulose phthalate and ethyl cellulose sulfate.

[0192] According to a particular embodiment of the present invention, the (c2) cellulose compound is non-associative. A "non-associative" cellulose compound is one that does not contain any fatty chains in its structure and preferably does not contain any C 10 -C 30 Chain cellulose polymer.

[0193] According to a first variant, the (c2) cellulose compound is nonionic. Mention may be made of (C1-C4) alkylcelluloses, such as methylcellulose and ethylcellulose (e.g. Ethocel standard 100 Premium from Dow Chemical); (poly) hydroxy (C1-C4) alkylcelluloses, such as hydroxymethylcellulose, hydroxyethylcellulose (e.g. Natrosol 250HHR supplied by Aqualon) and hydroxypropylcellulose (e.g. Klucel EF from Aqualon); mixed (poly) hydroxy (C1-C4) alkyl-(C1-C4) alkylcelluloses, such as hydroxypropylmethylcellulose (e.g. Methocel E4M from Dow Chemical); hydroxyethylmethylcellulose, hydroxyethylethylcellulose (e.g. Bermocoll E 481FQ from Akzo Nobel) and hydroxybutylmethylcellulose.

[0194] According to a second variant, the (c2) cellulose compound is anionic. Among the anionic cellulose ethers, mention may be made of (poly)carboxy(C1-C4)alkylcellulose and its salts. Examples that may be mentioned include carboxymethylcellulose, carboxymethylmethylcellulose (for example Blanose 7M from the company Aqualon) and carboxymethylhydroxyethylcellulose, and its sodium salt.

[0195] According to a third variant, the (c2) cellulose compound is cationic. Among the cationic celluloses, mention may be made of cationic cellulose derivatives, for example cellulose copolymers or cellulose derivatives grafted with water-soluble quaternary ammonium monomers and described in particular in US Pat. No. 4,131,576, for example (poly)hydroxy(C1-C4)alkylcelluloses such as hydroxymethylcellulose, hydroxyethylcellulose or hydroxypropylcellulose grafted in particular with methacryloylethyltrimethylammonium, methacrylamidopropyltrimethylammonium or dimethyldiallylammonium salts. Commercial products corresponding to this definition are more particularly those sold under the name CERTAINTY cellulose by the company National Starch. L 200 and Products sold by H 100.

[0196] According to another particular embodiment of the present invention, the (c2) cellulose compound is associative. An "associative" cellulose compound is one that contains any fatty chains in its structure, and preferably contains C 10 -C 30 Chain cellulose polymer.

[0197] The associative cellulose compounds may be cationic. Preferred among these cationic associative cellulose compounds are quaternized (poly)hydroxyethyl celluloses modified with groups containing at least one fatty chain, such as alkyl, aralkyl or alkaryl groups containing at least 8 carbon atoms, or mixtures of these. The alkyl groups carried by the above quaternized cellulose or hydroxyethyl cellulose preferably contain 8 to 30 carbon atoms. Aryl preferably represents phenyl, benzyl, naphthyl or anthracenyl. As the C8-C 30 As examples of quaternized alkylhydroxyethylcelluloses of fatty chains, mention may be made of the products Quatrisoft LM 200a, Quatrisoft LM-X 529-18-Aa, Quatrisoft LM-X 529-18-Ba(C 12 Alkyl) and Quatrisoft LM-X 529-8a (C 18 alkyl); products sold by Croda: Crodacel QMa, Crodacel QLa (C 12 Alkyl) and Crodacel QSa (C 18 alkyl); and the product sold by Aqualon, Softcat SL 100a.

[0198] The associative cellulose compound may be a nonionic one. Preferred among these nonionic associative cellulose compounds are those which are alkyl, aralkyl or alkaryl, or mixtures thereof (wherein the alkyl group is C8-C 30alkyl) or its derivatives, and in particular: nonionic alkylhydroxyethylcelluloses, such as the products Natrosol Plus Grade 330 CS and Polysurf 67 (C 67) sold by Aqualon. 16 nonionic nonoxynyl hydroxyethylcellulose, such as the product Amercell HM-1500 sold by Amerchol; nonionic alkyl cellulose, such as the product Bermocoll EHM100 sold by Berol Nobel.

[0199] The (c2) cellulose compound may preferably be nonionic or anionic and free of fatty chains (non-associative nonionic or anionic alkylcellulose polymers). Preferably, the (c2) cellulose compound useful in the present invention is selected from nonionic cellulose ethers, such as (C1-C4) alkylcelluloses, (poly)hydroxy(C1-C4) alkylcelluloses, (poly)hydroxy(C1-C4) alkyl-(C1-C4) alkylcelluloses, such as hydroxypropyl methylcellulose, hydroxyethyl methylcellulose, hydroxyethyl ethylcellulose, hydroxybutyl methylcellulose, hydroxymethylcellulose, hydroxyethylcellulose and hydroxypropylcellulose; and anionic cellulose ethers, such as carboxymethylcellulose, especially sodium carboxymethylcellulose.

[0200] Preferably, the (c2) cellulose compound is selected from unmodified cellulose and nonionic cellulose ethers or anionic cellulose ethers.

[0201] More preferably, the (c2) cellulose compound is selected from cellulose, cellulose gum, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, sodium carboxymethyl cellulose, and mixtures thereof.

[0202] The amount of (c2) cellulose compound in the composition according to the present invention may be 0.01 wt% or more, preferably 0.05 wt% or more, and more preferably 0.1 wt% or more, relative to the total weight of the composition.

[0203] On the other hand, the amount of (c2) cellulose compound in the composition according to the present invention may be 40 wt% or less, preferably 35 wt% or less, and more preferably 30 wt% or less, relative to the total weight of the composition.

[0204] Therefore, the amount of (c2) cellulose compound in the composition according to the invention may be 0.01% to 40% by weight, preferably 0.05% to 35% by weight and more preferably 0.01% to 30% by weight relative to the total weight of the composition.

[0205] [water] The composition according to the present invention comprises (d) water.

[0206] If the composition according to the invention comprises (c1) a skin care active ingredient, the amount of (d) water is as follows.

[0207] The amount of (d) water in the composition according to the present invention may be 30 wt% or more, preferably 35 wt% or more, and more preferably 40 wt% or more, relative to the total weight of the composition.

[0208] The amount of (d) water in the composition according to the present invention may be 60 wt% or less, preferably 55 wt% or less, and more preferably 50 wt% or less, relative to the total weight of the composition.

[0209] The amount of (d) water in the composition according to the invention may range from 30% to 60% by weight, preferably from 35% to 55% by weight, more preferably from 40% to 50% by weight, relative to the total weight of the composition.

[0210] On the other hand, if the composition according to the present invention contains the (c2) cellulose compound, the amount of (d) water is as follows.

[0211] The amount of (d) water in the composition according to the present invention may be 10 wt% or more, preferably 15 wt% or more, and more preferably 20 wt% or more, relative to the total weight of the composition.

[0212] The amount of (d) water in the composition according to the present invention may be 80 wt% or less, preferably 75 wt% or less, and more preferably 70 wt% or less, relative to the total weight of the composition.

[0213] The amount of (d) water in the composition according to the invention may range from 10% to 80% by weight, preferably from 15% to 75% by weight, more preferably from 20% to 60% by weight, relative to the total weight of the composition.

[0214] [Optional Ingredients] The composition according to the invention may further comprise at least one optional ingredient commonly used in the cosmetic field, for example selected from film-forming polymers, solvents, dyes, pigments, UV filters, antioxidants, preservatives, pH adjusters, and mixtures thereof.

[0215] The composition according to the invention may comprise one or several cosmetically acceptable organic solvents, which may be alcohols: in particular monohydric alcohols, such as ethanol, isopropanol, benzyl alcohol and phenylethyl alcohol; dihydric alcohols other than component (b), such as ethylene glycol; other polyhydric alcohols, such as glycerol, sugars and sugar alcohols; and ethers, such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether and ethylene glycol monobutyl ether, propylene glycol monomethyl ether, propylene glycol monoethyl ether and propylene glycol monobutyl ether, and butylene glycol monomethyl ether, butylene glycol monoethyl ether and butylene glycol monobutyl ether.

[0216] The amount of the organic solvent in the composition according to the present invention may be 0.01 wt % or more, preferably 0.1 wt % or more, and more preferably 1 wt % or more, relative to the total weight of the composition.

[0217] On the other hand, the amount of the organic solvent in the composition according to the present invention may be 30 wt % or less, preferably 20 wt % or less, and more preferably 10 wt % or less, relative to the total weight of the composition.

[0218] Thus, the amount of organic solvent in the composition according to the invention may range from 0.01% to 30% by weight, preferably from 0.1% to 20% by weight and more preferably from 1% to 10% by weight relative to the total weight of the composition.

[0219] (preparation) The composition according to the present invention can be prepared by mixing the essential ingredients as explained above and, if necessary, the optional ingredients as explained above.

[0220] The methods and means for mixing the above essential ingredients and optional ingredients are not limited. Any conventional methods and means may be used to mix the above essential ingredients and optional ingredients to prepare the composition according to the present invention.

[0221] [form] The form of the composition according to the present invention is not limited.

[0222] The composition according to the present invention may be thermodynamically stable and may be considered a single-phase composition.

[0223] The composition according to the invention may be transparent.

[0224] Transparency can be measured by measuring turbidity (for example, turbidity can be measured using a 2100Q (sold by the company Hach) with a circular cell (25 mm diameter and 60 mm height) and a tungsten lamp that emits visible light (between 400 nm and 800 nm, preferably 400-500 nm). The measurement can be carried out on the undiluted composition. A blank can be determined with distilled water.

[0225] The composition according to the present invention has a turbidity of 120 NTU or less, preferably 90 NTU or less and more preferably 60 NTU or less.

[0226] [Methods and Uses] Preferably, the composition according to the invention is a cosmetic or dermatological composition, preferably a skin cosmetic composition and more preferably a skin care cosmetic composition.

[0227] The composition according to the invention can be used in a non-therapeutic method, such as a cosmetic method, for treating the skin by application to the skin.

[0228] The invention therefore also relates to a cosmetic method for treating keratinous materials, such as the skin, comprising the step of applying to the keratinous materials a composition according to the invention.

[0229] The invention may also relate to the use of a composition according to the invention as or in a cosmetic product, such as a skin care product.

[0230] In other words, the composition according to the invention can be used as a cosmetic product as is. Alternatively, the composition according to the invention can be used as an element of a cosmetic product. For example, the composition according to the invention can be added to any other element or combined with any other element to form a cosmetic product.

[0231] Skin care products can be lotions, creams, serums, etc.

[0232] Another aspect of the present invention also relates to a method for preparing the composition, which comprises the steps of mixing the following ingredients: (a) at least one oil; (b) at least one diol having at least one carbon chain containing 3 or more carbon atoms; (c1) at least one skin care active ingredient; and (d) Water.

[0233] Preferably, the mixing step is carried out by a so-called low-energy method without a special mechanical stirrer such as a homogenizer that uses a large amount of energy. The low-energy method can be carried out by only gently stirring the ingredients (a) to (d).

[0234] Another aspect of the present invention relates to the use of (b) at least one diol having at least one carbon chain comprising 3 or more carbon atoms in a composition comprising (a) at least one oil, (c1) at least one skin care active ingredient and (d) water for enhancing or improving the penetration of (c1) the skin care active ingredient.

[0235] The present invention also relates to the use of (b) at least one diol having at least one carbon chain comprising 3 or more carbon atoms as a skin penetration enhancer for (c1) at least one skin care active ingredient in a composition comprising (a) at least one oil and (d) water.

[0236] Another aspect of the present invention also relates to a method for preparing the composition, which comprises the steps of mixing the following ingredients: (a) at least one oil; (b) at least one diol having at least one carbon chain containing 3 or more carbon atoms; (c2) at least one cellulose compound; and (d) Water.

[0237] Preferably, the mixing step is carried out by a so-called low-energy method without a special mechanical stirrer such as a homogenizer that uses a large amount of energy. The low-energy method can be carried out by only gently stirring the ingredients (a) to (d).

[0238] Another aspect of the present invention relates to the use of (c2) at least one cellulose compound in a composition comprising (a) at least one oil, (b) at least one glycol having at least one carbon chain comprising 3 or more carbon atoms and (d) water for enhancing the radiance of the skin to which the composition according to the invention is applied.

[0239] The present invention also relates to the use of (c2) at least one cellulose compound as a skin radiance enhancer for a composition comprising (a) at least one oil, (b) at least one glycol having at least one carbon chain containing 3 or more carbon atoms and (d) water.

[0240] Preferably, the above composition in the uses and methods according to the invention is in the form of a microemulsion (and more preferably an O / W microemulsion).

[0241] The explanations above for the composition according to the invention about components (a) to (d), and optional ingredients, can be applied to those for the uses and methods according to the invention. The explanations about the preparation and form of the composition according to the invention can also be applied to those of the composition described in the above uses and methods. Example The present invention will be described in more detail through examples, however, the examples should not be construed as limiting the scope of the present invention.

[0243] Examples 1A-6A and Comparative Examples 1A-12A The following compositions according to Examples 1A-6A and Comparative Examples 1A-12A shown in Tables 1A-3A were prepared by mixing the ingredients shown in Tables 1A-3A below. Symbols "(a)", "(b)", "(c1)" and "(d)" in Tables 1A-3A correspond to those in the claims. The numerical values ​​for the amounts of the ingredients shown in Tables 1A-3A are all based on "% by weight" of the active raw material. Table 1A Table 2A Table 3A

[0244] [Evaluate] (Active ingredient penetration) On a Strat-M membrane (Merck, surface area: 1.77 cm 2 The permeation test experiment was carried out in a Franz diffusion cell (PermeGear) of a 3000MW RT-PCR apparatus. The apparatus consists of a donor part and a receiver part and a Strat-M membrane between the donor part and the receiver part. The receiver part having a predetermined volume was filled with a receiver solution (0.25 wt % Tween 80 / deionized water) maintained at a temperature of 32° C., and the receiver solution was continuously stirred with a small magnetic bar. The compositions according to Examples 1A-6A and Comparative Examples 1A-12A were each scalded with a spatula at 20 mg / cm 2 The amount of the receiving solution was applied to the membrane of the donor part. After 1 hour, 200 μl of the receiving solution was taken out from the receiving part, and the same amount of new receiving solution was supplied to the receiving part to maintain the same permeation conditions. The taken out receiving solution was analyzed by HPLC to determine the amount of active ingredient in the receiving solution. The percentage of active ingredient that passed through the membrane was calculated by dividing the detected amount of active ingredient in the receiving solution by the amount of active ingredient applied to the membrane.

[0245] The results are shown in the "Permeation of Active Ingredient" row in Tables 1A-3A.

[0246] [Summarize] Tables 1A-3A demonstrate that compositions comprising (a) at least one oil, (b) at least one glycol having at least one carbon chain comprising 3 or more carbon atoms, (c1) at least one skin care active ingredient, and (d) water can provide enhanced skin penetration of the (c1) skin care active ingredient.

[0247] Tables 1A-3A also demonstrate that the use of (b) at least one diol having at least one carbon chain containing 3 or more carbon atoms in a composition comprising (a) at least one oil, (c1) at least one skin care active ingredient, and (d) water can enhance or improve the penetration of the (c1) skin care active ingredient.

[0248] Examples 1B-5B and Comparative Examples 1B-8B The following compositions according to Examples 1B-5B and Comparative Examples 1B-8B shown in Table 1B were prepared by mixing the ingredients shown in Table 1B below. The numerical values ​​for the amounts of the ingredients shown in Table 1B are all based on "weight %" of the active raw materials.

[0249] [Evaluate] (Appearance) Based on the following criteria, the appearance of each of the compositions according to Examples 1B-6B and Comparative Examples 1B-8B was evaluated by visually observing the compositions kept at 55° C. for 2 weeks and at 4° C. for 2 weeks.

[0250] Good: Even Poor: Inhomogeneous (phase separation detected) The results are shown in Table 1B.

[0251] (transparency) Based on the following criteria, the transparency of each of the compositions according to Examples 1B to 6B and Comparative Examples 1B to 8B was evaluated by visually observing the compositions kept at 55° C. for 2 weeks and at 4° C. for 2 weeks.

[0252] Good: Transparent Acceptable: Translucent Poor: Opaque The results are shown in Table 1B.

[0253] (Freshness) The compositions according to Examples 1B-6B and Comparative Examples 1B-8B were each applied to the panelists' forearms in an amount of 100 μm and gently massaged with fingers. The freshness during those steps was evaluated based on the following criteria.

[0254] Very fresh: 5 Freshness: 4 Slightly fresh: 3 Slightly fresh: 2 Not fresh: 1 The average scores tested by 5 skin care assessment experts are shown in Table 1B.

[0255] (luster) The compositions according to Examples 1B-6B and Comparative Examples 1B-8B were each evenly applied in an amount of 45 μm to a 3.0 cm*3.0 cm area (5 μm / cm 2 ) and leave it for 1.5 hours. The gloss of the above area was evaluated based on the following criteria.

[0256] Strong gloss: 5 Gloss: 4 Slightly glossy: 3 Faint Gloss: 2 Matte: 1 The average scores tested by 5 skin care assessment experts are shown in Table 1B.

[0257] [Summarize] The compositions according to Examples 1B-6B can provide enhanced skin radiance while providing a fresh feel upon use.

[0258] The compositions according to Examples 1B-6B were homogeneous and transparent.

[0259] On the other hand, the compositions according to Comparative Examples 1B-8B could not provide enhanced skin radiance. However, they were able to provide a fresh touch upon use.

[0260] In addition, the composition according to Comparative Example 7B was not uniform.

[0261] Table 1B demonstrates that the combination of (a) at least one oil, (b) at least one glycol having at least one carbon chain containing 3 or more carbon atoms, (c2) at least one cellulosic compound, and (d) water is necessary to provide a composition that enhances the radiance of the skin while providing a fresh texture upon use compared to a composition in which ingredient (c2) is not used.

[0262] Table 1B also demonstrates that the use of (c2) at least one cellulosic compound in a composition comprising (a) at least one oil, (b) at least one diol having at least one carbon chain containing 3 or more carbon atoms and (d) water can enhance the radiance of the skin to which the composition according to the invention is applied.

Claims

1. A composition comprising: (a) at least one oil; (b) at least one diol having at least one carbon chain containing 3 or more carbon atoms; (c) (c1) at least one skin care active ingredient or (c2) at least one cellulose compound; and (d) Water.

2. The composition according to claim 1, wherein the (a) oil is selected from the group consisting of (i) fatty alcohols, (ii) fatty acids, (iii) monocarboxylic acid monoesters, (iv) dicarboxylic acid diesters, (v) N-acyl amino acid esters and (vi) alkyl lactates, with the proviso that: - the (i) fatty alcohol and the (ii) fatty acid contain a branched alkyl group, or a straight or branched alkenyl group, each of which has 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, - the (iii) monocarboxylic acid monoester comprises a branched alkyl group, or a straight or branched alkenyl group, each of which has 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, - the (iv) dicarboxylic acid diester comprises at least one branched alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms; and an alkenyl group having 6 to 18 carbon atoms, preferably 6 to 14 carbon atoms, and more preferably 6 to 10 carbon atoms, - the (v) N-acyl amino acid ester comprises a branched alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms; and a straight or branched acyl group having 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, and - The (vi) alkyl lactate contains a linear or branched alkyl group, or a linear or branched alkenyl group, each of which has 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms.

3. The composition according to claim 1 or 2, wherein the (a) oil is selected from (v) N-acyl amino acid esters, which contain at least a branched alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms, preferably (v) N-acyl amino acid esters represented by the following general formula (5): R 2 -N(R 5 )-CH(R 6 )-(CH2) n -COO-R 3 (5) in R 2 represents a straight-chain or branched acyl group having 4 to 30 carbon atoms, preferably 5 to 26 carbon atoms, and more preferably 6 to 22 carbon atoms, R 3 represents a branched alkyl group having 3 to 10 carbon atoms, preferably 3 to 8 carbon atoms, and more preferably 3 to 6 carbon atoms, R 5 represents a hydrogen atom or a straight-chain or branched alkyl group having 1 to 4 carbon atoms, R 6 represents a hydrogen atom or a straight or branched alkyl group having 1 to 4 carbon atoms which may be substituted with a hydroxyl group or a phenyl group, and n represents an integer from 0 to 2, And more preferably, the (a) oil is isopropyl lauroyl sarcosinate.

4. The composition according to any one of claims 1 to 3, wherein the amount of the (a) oil in the composition ranges from 0.5 wt% to 25 wt%, preferably from 1 wt% to 20 wt%, and more preferably from 2 wt% to 15 wt%, relative to the total weight of the composition.

5. The composition of any one of claims 1 to 4, wherein the (b) diol having at least one carbon chain containing 3 or more carbon atoms is selected from propylene glycol, dipropylene glycol, polypropylene glycol, butylene glycol, dibutylene glycol, polybutylene glycol, pentylene glycol, dipentylene glycol, hexylene glycol, dihexylene glycol, and mixtures thereof.

6. The composition according to any one of claims 1 to 5, wherein the weight ratio of the amount of the (b) diol having at least one carbon chain containing 3 or more carbon atoms to the amount of the (a) oil is 4 or more, preferably 5 or more, and more preferably 6 or more.

7. The composition according to any one of claims 1 to 6, wherein the (c1) skin care active ingredient has a Log P value of 4 or less, preferably -4.5 to 4.0, and more preferably -4.0 to 3.

5.

8. The composition according to any one of claims 1 to 7, wherein the (c1) skin care active ingredient is a skin care cosmetic active ingredient, preferably a skin whitening or anti-wrinkle ingredient, and more preferably selected from ascorbyl glucoside, 3-O-ethyl ascorbic acid, tranexamic acid, hydroxypropyl tetrahydropyrantriol, niacinamide, salicylic acid, phenethyl resorcinol, and mixtures thereof.

9. The composition according to any one of claims 1 to 8, wherein the amount of the (c1) skin care active ingredient in the composition ranges from 0.01 wt% to 25 wt%, preferably from 0.05 wt% to 20 wt%, and more preferably from 0.1 wt% to 15 wt%, relative to the total weight of the composition.

10. The composition according to any one of claims 1 to 9, wherein the (c2) cellulose compound is selected from unmodified cellulose and nonionic cellulose ethers or anionic cellulose ethers.

11. The composition according to any one of claims 1 to 10, wherein the (c2) cellulose compound is selected from the group consisting of cellulose, cellulose gum, hydroxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, sodium carboxymethyl cellulose, and mixtures thereof.

12. A composition according to any one of claims 1 to 11, wherein the amount of the (c2) cellulose compound in the composition ranges from 0.01 wt% to 40 wt%, preferably from 0.05 wt% to 35 wt%, and more preferably from 0.1 wt% to 30 wt%, relative to the total weight of the composition.

13. The composition according to any one of claims 1 to 12, wherein the composition has a turbidity of 120 NTU or less, preferably 90 NTU or less and more preferably 60 NTU or less.

14. The composition according to any one of claims 1 to 13, wherein the composition is a cosmetic composition, preferably a skin cosmetic composition, and more preferably a skin care cosmetic composition.

15. A cosmetic method for treating keratinous materials, preferably the skin, comprising the step of applying to said keratinous materials a composition according to any one of claims 1 to 14.

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