Urinary surgery stent with drug release function
By designing a urological stent with drug release function, using activated carbon filter plate and drug storage bag structure, the problems of stent slippage and airbag tube infection are solved, and the effective release of drugs and the degradability of the material are achieved.
Patent Information
- Application Number
- CN202510073157.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-17
- Publication Date
- 2025-03-28
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
When pushing a urological stent, the stent may slip and cause displacement, and the airbag tube is prone to introduce external odor or bacteria when inflated, leading to the risk of infection.
A urological stent with drug release function is designed, including balloons, airbag tubes and stent structures. External gas is filtered through activated carbon filter plates to avoid odors and bacteria entering, and the stent does not detach during the push process through the storage bag and bump structure.
Effectively avoid the risks of stent slippage and airbag tube infection, ensure effective release of drugs at the lesions, and improve the compatibility and degradability of drugs through biodegradable polymer materials.
Smart Images
Figure CN119700389A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of urological stents, in particular to a urological stent with a drug releasing function. Background Art
[0002] Ureteral stenosis is a very common disease in the diagnosis and treatment of clinical diseases in urology. Once it occurs, it often causes symptoms such as ureteral dilatation and hydronephrosis above the stenotic segment, affecting the normal excretion of the ipsilateral kidney, seriously affecting the function of the ipsilateral kidney, and even causing the kidney on that side to lose its function. Early and active treatment should be given after clinical discovery. When urological stents are used, the surface of the stent is usually coated with drugs, so that the drugs can be released during expansion to promote repair.
[0003] However, when the stent is pushed, the stent may slip before reaching the patient, causing the stent to be displaced, and when the balloon tube is inflated by the balloon, external odors or bacteria can easily enter the balloon tube. When the balloon tube is slightly damaged, it can easily cause internal infection in the patient. Therefore, it does not meet the existing needs. In response to this, we have proposed a urological stent with drug release function. Summary of the invention
[0004] The purpose of the present invention is to provide a urological stent with a drug release function to solve the problem raised in the above-mentioned background technology that when the stent is pushed, the stent may slip before reaching the patient's site, causing the stent to be displaced, and when the balloon tube is inflated by a balloon, external odors or bacteria can easily enter the balloon tube, and when the balloon tube is slightly damaged, it can easily cause internal infection in the patient.
[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a urological surgical stent with a drug release function, comprising a balloon, an airbag tube and a stent structure, wherein the balloon and the airbag tube are connected via an air inlet pipe, and the stent structure is arranged on the outer surface of the airbag tube, and a connecting seat is arranged between the connection between the balloon and the air inlet pipe, and a connecting groove is arranged inside the connecting seat, and an activated carbon filter plate is detachably connected to the inside of the connecting groove, and a guide column is connected to the end of the airbag tube away from the air inlet pipe, and a camera and a searchlight are arranged at the end of the guide column away from the airbag tube, and the stent structure comprises a grid stent, a polymer layer and a drug layer, the polymer layer is wrapped around the outer surface of the grid stent, and the drug layer is wrapped around the outer surface of the polymer layer, and a drug storage bag is arranged between the airbag tube and the stent structure, and a plurality of protrusions are fixedly connected to the outer surface of the drug storage bag, and the protrusions penetrate through the interior of the grid stent and are clamped.
[0006] Preferably, one end of the medicine storage bag is threadedly connected to a sealing cover, and a through hole is provided on the surface of each of the protrusions to be connected to the inside of the medicine storage bag.
[0007] Preferably, one end of the balloon away from the air inlet pipe is connected to a one-way valve, and one end of the air inlet pipe close to the balloon is connected to a deflation valve.
[0008] Preferably, driving cavities are provided on both sides of the connecting seat close to the upper end, and movable cavities are provided below the two driving cavities and inside the connecting seat.
[0009] Preferably, one end of the two driving cavities is fixedly connected with an internal thread ring, and both sides of the outer surface of the connecting seat are threadedly connected with a semi-threaded rod extending into the driving cavity through the internal thread ring.
[0010] Preferably, the interiors of the two active cavities are movably connected with a connecting rod extending through the driving cavity, the bottom end of the connecting rod is fixedly connected to a limiting block, a spring is fixedly connected between the upper end of the limiting block and the top end of the inner wall of the active cavity, and the spring is wrapped around the outer surface of the connecting rod.
[0011] Preferably, one end of the semi-threaded rod close to the inside of the driving cavity and the top end of the connecting rod are both arranged in an inclined surface, and the semi-threaded rod is in sliding contact with the inclined surface of the connecting rod, and one end of the limit block movably extends through the inside of the connecting groove.
[0012] Preferably, the outer surface of the activated carbon filter plate is sealed to the inner wall of the connecting groove by a sealing gasket, and limiting grooves are provided on both sides of the upper end of the activated carbon filter plate, and the limiting block extends through one end of the connecting groove and is plugged into the corresponding limiting groove.
[0013] Preferably, the grid stent is a cylindrical structure woven from nickel-titanium alloy wires.
[0014] Preferably, the polymer layer is made of a biodegradable polymer.
[0015] Compared with the prior art, the present invention has the following beneficial effects: 1. The present invention loads the drug body into the drug storage bag, and coats the drug layer on the outer surface of the stent structure. The polymer layer is a biodegradable polymer, so that the drug has better compatibility and degradability, and can be gradually decomposed in the body. Then, the balloon tube is pushed into the ureter, and the bumps on the outer surface of the drug storage bag are clamped on the outer surface of the grid stent, so that the stent structure can be prevented from being detached. 2. When the present invention moves to the patient's site through the balloon tube and the stent structure, the balloon is squeezed to allow external gas to enter the balloon through the one-way valve, and is filtered and adsorbed by the activated carbon filter plate, thereby preventing external odor or bacteria from easily entering the balloon tube. The gas is transported to the inside of the balloon tube through the air inlet pipe, and then the balloon tube is expanded, driving the grid stent support to expand, thereby supporting the stenosis or obstruction, and then the drug layer on the outer surface of the polymer layer is released to the lesion for repair, and the balloon tube is expanded to squeeze the drug storage bag, so that the drug inside the drug storage bag is released through the through hole, thereby preventing the drug on the outer surface from being used up before the balloon tube reaches the lesion; 3. The present invention rotates the semi-threaded rod so that the semi-threaded rod thread rotates with the internal threaded ring, thereby releasing the contact with the connecting rod. Then the spring on the outer surface of the connecting rod releases the elastic force and resets, thereby driving the limit block to disengage from the limit groove and move and shrink back into the active cavity. Then the activated carbon filter plate can be taken out from the inside of the connecting groove for replacement, avoiding over-adsorption of the activated carbon filter plate, which affects the use of the balloon and the airbag tube. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] Figure 1 It is a schematic diagram of the overall structure of the present invention; Figure 2 is a front cross-sectional view of the airbag tube of the present invention; Figure 3 is a front cross-sectional view of the balloon of the present invention; Figure 4 It is a structural schematic diagram of the support structure of the present invention; Figure 5 For the present invention Figure 2 The structural diagram at A in the middle; Figure 6 For the present invention Figure 3 Schematic diagram of the structure at B in the figure.
[0017] In the figure: 1. balloon; 2. balloon tube; 3. air inlet pipe; 4. support structure; 401. grid support; 402. polymer layer; 403. drug layer; 5. one-way valve; 6. connecting seat; 601. connecting groove; 602. driving chamber; 603. movable chamber; 7. deflation valve; 8. guide column; 9. camera; 10. searchlight; 11. drug storage bag; 12. sealing cover; 13. bump; 1301. through hole; 14. activated carbon filter plate; 1401. limiting groove; 15. internal thread ring; 16. semi-threaded rod; 17. connecting rod; 18. limiting block; 19. spring. DETAILED DESCRIPTION
[0018] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.
[0019] See also Figures 1 to 6 An embodiment of the present invention provides a urological stent with drug release function, comprising a balloon 1, an airbag tube 2 and a stent structure 4, wherein the balloon 1 and the airbag tube 2 are connected via an air inlet tube 3, the stent structure 4 is arranged on the outer surface of the airbag tube 2, a connecting seat 6 is arranged between the balloon 1 and the air inlet tube 3, a connecting groove 601 is arranged inside the connecting seat 6, an activated carbon filter plate 14 is detachably connected inside the connecting groove 601, and the filtration and adsorption of the activated carbon filter plate 14 can prevent external odor or bacteria from easily entering the airbag tube 2, a guide column 8 is connected to the end of the airbag tube 2 away from the air inlet tube 3, a camera 9 and a searchlight 10 are arranged on the end of the guide column 8 away from the airbag tube 2, and the searchlight 1 0 and camera 9, can observe the internal condition of the ureter, the support structure 4 includes a mesh support 401, a polymer layer 402 and a drug layer 403, the polymer layer 402 is wrapped on the outer surface of the mesh support 401, the mesh support 401 is a cylindrical structure woven from nickel-titanium alloy wires, and the drug layer 403 is wrapped on the outer surface of the polymer layer 402, a drug storage bag 11 is provided between the balloon tube 2 and the support structure 4, a plurality of protrusions 13 are fixedly connected to the outer surface of the drug storage bag 11, and the protrusions 13 pass through and are clamped in the interior of the mesh support 401, and the protrusions 13 on the outer surface of the drug storage bag 11 are clamped on the outer surface of the mesh support 401, which can prevent the support structure 4 from detaching before reaching the lesion.
[0020] One end of the medicine storage bag 11 is threadedly connected to a sealing cover 12, and the surface of each protrusion 13 is provided with a through hole 1301 that is connected to the inside of the medicine storage bag 11. The medicine body is loaded into the inside of the medicine storage bag 11 and then expanded through the airbag tube 2, thereby squeezing the medicine storage bag 11, so that the medicine inside the medicine storage bag 11 is released through the through hole 1301, thereby preventing the airbag tube 2 from reaching the lesion before the medicine on the outer surface is used up. The polymer layer 402 is made of a biodegradable polymer, and the polymer layer 402 is a biodegradable polymer, so that the drug has better compatibility and degradability, and can be gradually decomposed in the body.
[0021] Both sides of the connecting seat 6 near the upper end are provided with driving cavities 602, and movable cavities 603 are provided below the two driving cavities 602 and inside the connecting seat 6, and one end of the two driving cavities 602 is fixedly connected with an internal thread ring 15, and both sides of the outer surface of the connecting seat 6 are threadedly connected with a semi-threaded rod 16 extending into the driving cavity 602 through the internal thread ring 15, and the interiors of the two movable cavities 603 are movably connected with a connecting rod 17 extending into the driving cavity 602, and the bottom end of the connecting rod 17 is fixedly connected to a limiting block 18, and between the upper end of the limiting block 18 and the top of the inner wall of the movable cavity 603 A spring 19 is fixedly connected and wound around the outer surface of the connecting rod 17. One end of the semi-threaded rod 16 close to the inside of the driving chamber 602 and the top of the connecting rod 17 are both inclined, and the semi-threaded rod 16 is in sliding contact with the inclined surface of the connecting rod 17. One end of the limit block 18 movably extends through the inside of the connecting groove 601. The outer surface of the activated carbon filter plate 14 and the inner wall of the connecting groove 601 are sealed and connected by a sealing gasket. Limiting grooves 1401 are provided on both sides of the upper end of the activated carbon filter plate 14. One end of the limit block 18 extends through the inside of the connecting groove 601 and is plugged into the corresponding limit groove 1401.
[0022] By rotating the semi-threaded rod 16, the semi-threaded rod 16 is threadedly rotated with the internal threaded ring 15, thereby releasing the contact with the connecting rod 17, and then the spring 19 on the outer surface of the connecting rod 17 releases the elastic force and resets, thereby driving the limit block 18 to disengage from the limit groove 1401 and move and retract back into the active cavity 603. Then the activated carbon filter plate 14 can be taken out from the inside of the connecting groove 601 for replacement to avoid over-adsorption of the activated carbon filter plate 14, which affects the use of the balloon 1 and the airbag tube 2.
[0023] Working principle: When the urological stent is used, the medicine body is loaded into the medicine storage bag 11, and the medicine layer 403 is coated on the outer surface of the stent structure 4. The polymer layer 402 is a biodegradable polymer, so that the medicine has better compatibility and degradability, and can be gradually decomposed in the body. Then the balloon tube 2 is pushed into the ureter, and the bump 13 on the outer surface of the medicine storage bag 11 is clamped on the outer surface of the grid stent 401 to prevent the stent structure 4 from detaching. Then, the searchlight 10 and the camera 9 can be used to observe the internal conditions of the ureter. When the balloon tube 2 and the stent structure 4 are moved to the patient's site, the balloon tube 2 and the stent structure 4 are connected to the patient's site. The balloon 1 is squeezed to allow external gas to enter the inside of the balloon 1 through the one-way valve 5, and after being filtered and adsorbed by the activated carbon filter plate 14, the gas is transported to the inside of the balloon tube 2 through the air inlet pipe 3, and then the balloon tube 2 is expanded, and the grid support 401 is driven to support and expand, thereby supporting the stenosis or obstruction, and then the drug layer 403 on the outer surface of the polymer layer 402 is released to the lesion for repair, and the balloon tube 2 is expanded to squeeze the drug storage bag 11, so that the drug inside the drug storage bag 11 is released through the through hole 1301, so as to avoid the balloon tube 2 not reaching the lesion, and the drug on the outer surface is used up; By rotating the semi-threaded rod 16, the semi-threaded rod 16 is threadedly rotated with the internal threaded ring 15, thereby releasing the contact with the connecting rod 17, and then the spring 19 on the outer surface of the connecting rod 17 releases the elastic force and resets, thereby driving the limit block 18 to disengage from the limit groove 1401 and move and retract back into the active cavity 603. Then the activated carbon filter plate 14 can be taken out from the inside of the connecting groove 601 for replacement to avoid over-adsorption of the activated carbon filter plate 14, which affects the use of the balloon 1 and the airbag tube 2.
[0024] It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above and that the invention can be implemented in other specific forms without departing from the spirit or essential features of the invention. Therefore, the embodiments should be considered exemplary and non-limiting in all respects, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations falling within the meaning and scope of the equivalent elements of the claims be included in the invention. Any reference numeral in a claim should not be considered as limiting the claim to which it relates.
Claims
1. A urological stent with a drug release function, comprising a balloon (1), an airbag tube (2) and a stent structure (4), wherein the balloon (1) and the airbag tube (2) are connected via an air inlet tube (3), and the stent structure (4) is arranged on the outer surface of the airbag tube (2), characterized in that: A connection seat (6) is provided between the balloon (1) and the air intake pipe (3), a connection groove (601) is provided inside the connection seat (6), an activated carbon filter plate (14) is detachably connected inside the connection groove (601), a guide column (8) is connected to one end of the airbag tube (2) away from the air intake pipe (3), a camera (9) and a searchlight (10) are provided on one end of the guide column (8) away from the airbag tube (2), the support structure (4) comprises a grid support (401), a polymer layer (402) and a drug layer (403), the polymer layer (402) is wrapped around the outer surface of the grid support (401), and the drug layer (403) is wrapped around the outer surface of the polymer layer (402), a drug storage bag (11) is provided between the airbag tube (2) and the support structure (4), a plurality of protrusions (13) are fixedly connected to the outer surface of the drug storage bag (11), and the protrusions (13) penetrate through and are clamped in the interior of the grid support (401).
2. The urological stent with drug release function according to claim 1, characterized in that: One end of the medicine storage bag (11) is threadedly connected to a sealing cover (12), and a through hole (1301) is provided on the surface of each of the protrusions (13) and is connected to the interior of the medicine storage bag (11).
3. The urological stent with drug release function according to claim 1, characterized in that: The end of the balloon (1) away from the air inlet pipe (3) is connected to a one-way valve (5), and the end of the air inlet pipe (3) close to the balloon (1) is connected to a deflation valve (7).
4. The urological stent with drug release function according to claim 1, characterized in that: The connection seat (6) is provided with driving cavities (602) on both sides close to the upper end, and a movable cavity (603) is provided below the two driving cavities (602) and inside the connection seat (6).
5. The urological stent with drug release function according to claim 4, characterized in that: One end of the interior of the two drive cavities (602) is fixedly connected to an internal threaded ring (15), and both sides of the outer surface of the connection seat (6) are threadedly connected to a semi-threaded rod (16) extending through the interior of the drive cavity (602) via the internal threaded ring (15).
6. The urological stent with drug release function according to claim 5, characterized in that: The interiors of the two movable chambers (603) are movably connected to a connecting rod (17) extending through the interior of the driving chamber (602); the bottom end of the connecting rod (17) is fixedly connected to a limiting block (18); a spring (19) is fixedly connected between the upper end of the limiting block (18) and the top end of the inner wall of the movable chamber (603); and the spring (19) is wound around the outer surface of the connecting rod (17).
7. The urological stent with drug release function according to claim 6, characterized in that: One end of the semi-threaded rod (16) close to the interior of the driving cavity (602) and the top end of the connecting rod (17) are both arranged in an inclined surface, and the semi-threaded rod (16) is in sliding contact with the inclined surfaces of the connecting rod (17), and one end of the limit block (18) movably extends through the interior of the connecting groove (601).
8. The urological stent with drug release function according to claim 7, characterized in that: The outer surface of the activated carbon filter plate (14) is sealed to the inner wall of the connection groove (601) via a sealing gasket, and limiting grooves (1401) are provided on both sides of the upper end of the activated carbon filter plate (14), and one end of the limiting block (18) extends through the interior of the connection groove (601) and is plugged into the corresponding limiting groove (1401).
9. The urological stent with drug release function according to claim 1, characterized in that: The mesh stent (401) is a cylindrical structure woven from nickel-titanium alloy wires.
10. The urological stent with drug release function according to claim 1, characterized in that: The polymer layer (402) is made of biodegradable polymer.