Application of ursodesoxycholic acid in preparation of medicament for improving survival rate of acute hepatopancreatic necrosis disease of prawns

By using ursodeoxycholic acid (UDCA) in the agent for acute hepatopancreatic necrosis of shrimp, the bile acid metabolism of shrimp was solved, and the survival rate and health status of shrimps in the prior art was significantly improved.

CN119700776AActive Publication Date: 2025-03-28SHANDONG ACAD OF MARINE SCI (QINGDAO NAT MARINE SCI RES CENT) +2
7 Cites 0 Cited by

Patent Information

Application Number
CN202510022703.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-07
Publication Date
2025-03-28
Estimated Expiration
2045-01-07

AI Technical Summary

Technical Problem

The prior art is difficult to effectively improve the survival rate of acute hepatopancreatic necrosis in shrimps, and the existing prevention and treatment measures are average and it is difficult to meet production needs.

Method used

Ursodeoxycholic acid (UDCA) is used as the agent component to reduce the damage to shrimp cells by pathogenic Vibrio. UDCA can be fed by intramuscular injection or addition to feed, regulate bile acid metabolism, inhibit excessive reflux and synthesis of bile acids, and maintain bile acid metabolism homeostasis.

Benefits of technology

It significantly alleviated the symptoms and mortality rate after acute hepatopancreatic necrosis infection in shrimp, improved the survival rate of shrimp, and reduced damage to the hepatopancreas and intestinal tract.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The invention provides application of ursodesoxycholic acid in preparation of a medicament for improving the survival rate of acute hepatopancreatic necrosis of prawns, and belongs to the technical field of disease prevention and control in prawn culture. According to the invention, a lipid metabolism regulator ursodesoxycholic acid (UDCA) is adopted, and the damage of pathogenic vibrio infection to prawns is obviously reduced by regulating and controlling the metabolic pathway of infected prawn bodies. Tests prove that no matter the ursodesoxycholic acid is injected or added into the feed for feeding, the symptoms and the death rate of the prawns infected with the acute hepatopancreatic necrosis disease are remarkably reduced, and the ursodesoxycholic acid has a certain prevention and treatment effect in the prevention and treatment of the acute hepatopancreatic necrosis disease of the prawns.
Need to check novelty before this filing date? Find Prior Art