Ganoderma lucidum polysaccharide-astragalus gum-bacterial cellulose medical catheter and preparation method thereof

By using a combination of Ganoderma lucidum polysaccharide, astragalus gum and bacterial cellulose, the biocompatibility and immune response problems of existing catheters when they are left in the body for a long time is solved, and a catheter with high biocompatibility and drug-carrying performance is achieved, meeting the needs of complex medical behaviors.

CN119701102AInactive Publication Date: 2025-03-28南通市中医院(南通市中医研究所)
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Patent Information

Application Number
CN202411835904.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-13
Publication Date
2025-03-28
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

When existing medical catheters are left in the body for a long time, there are problems of biocompatibility and immune response, which is difficult to meet the needs of blood flow monitoring, infusion and intravenous nutritional support under complex medical behaviors.

Method used

Medical catheters are prepared using a combination of Ganoderma lucidum polysaccharide, astragalus gum and bacterial cellulose. A hollowed-in circular tube mesh stent is formed through a specific preparation method, and the mixed solution is loaded to improve biocompatibility and drug-loading performance.

Benefits of technology

It realizes the non-toxicity and immunologic inertia of medical catheters, improves the biocompatibility with blood contact, provides the necessary nutrient delivery pathways and growth space for nerve cell growth, and meets the needs of complex medical behaviors.

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Abstract

The invention discloses a ganoderan-astragalus gum-bacterial cellulose medical catheter. Each 100ml of medical catheter preparation solution is prepared from the following components: 1 to 10g of ganoderan, 1 to 10g of bacterial cellulose, 2 to 30mL of 10 percent astragalus gum solution and 10 to 100mL of aqueous solution. The raw materials in the formula are wide in source and low in price, and have the surface adsorption, interception and grafting functions of medical polymer materials. The medical catheter prepared according to the formula of the invention is non-toxic and immunological inert, and the biocompatibility of a medical polymer material in contact with blood is improved. According to the formula, the catheter prepared through the mold has a rich three-dimensional structure, a necessary way can be provided for conveying nutrient substances needed in the growth process of nerve cells, and a necessary induction effect and a necessary growth space are provided for growth of the nerve cells.
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