Multi-dimensional monitoring satiety and stomach-occupying capsule effect evaluation optimization method
Through multi-dimensional monitoring methods, including collecting satiety scores, tracking the gastric emptying process, and long-term monitoring of changes in food consumption and weight, comprehensively assessing the effect of gastric capsules, and determining whether the use plan is needed based on fuzzy reasoning, the problem of incomplete and accurate evaluation methods in the existing technology is solved, and personalized optimization and optimization of the effect is achieved.
Patent Information
- Application Number
- CN202510220725.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-27
- Publication Date
- 2025-03-28
- Estimated Expiration
- 2045-02-27
AI Technical Summary
The method for evaluating the effect of Zhanwei capsules in the prior art relies on a single subjective feeling or simple quantitative indicators, and cannot comprehensively and accurately monitor and evaluate its actual effect in different usage situations.
The multi-dimensional monitoring method was used to collect the VAS scores of the visual analog scales of gastric capsules taken at different times, and combined with Kaplan-Meier curve analysis, the rate of satiety change was calculated. At the same time, radiotracers were used to track the gastric emptying process, build a satiety model, generate a satiety evaluation coefficient, and long-term monitoring of changes in intake and weight change rate to comprehensively evaluate the effect of gastric capsules, and judge whether the use plan needs to be optimized based on fuzzy reasoning.
A comprehensive and accurate assessment of the effect of Guanwei Capsules has been achieved, personalized optimization suggestions are provided, and the accuracy and personalization of the effect are improved, ensuring that users can obtain the best results during use, and helping users achieve health management goals through long-term effect tracking.
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Figure CN119719690A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the field of evaluation optimization technology, and more specifically, to a multi-dimensional monitoring method for optimizing satiety and stomach-occupying capsule effect evaluation. Background Art
[0002] With the increasing demand for health management in modern society, weight management and appetite control have become the focus of more and more people. As a product for controlling appetite, Zhanwei Capsules fill the stomach cavity to produce a sense of fullness, helping to slow down food intake and improve weight management.
[0003] Deficiencies of existing technologies:
[0004] The existing methods for evaluating the effects of Zhanwei capsules have certain limitations, often relying on a single subjective feeling or simple quantitative indicators, and are unable to comprehensively and accurately monitor and evaluate their actual effects in different usage scenarios. Therefore, the present invention uses a multi-angle monitoring method to comprehensively evaluate the effects of Zhanwei capsules on producing satiety, and continuously optimizes the evaluation process to ensure the best effect.
[0005] In view of the above problems, the present invention proposes a solution. Summary of the invention
[0006] In order to overcome the above-mentioned defects of the prior art, an embodiment of the present invention provides a multi-dimensional monitoring method for satiety and stomach-satisfying capsule effect evaluation and optimization method. Through a multi-angle monitoring method, the effect of the stomach-satisfying capsule on producing satiety is comprehensively evaluated, and the evaluation process is continuously optimized to solve the problems raised in the above-mentioned background technology.
[0007] To achieve the above object, the present invention provides the following technical solutions:
[0008] A multi-dimensional monitoring method for satiety and the optimization of the effect evaluation of Zhanwei capsules, comprising: collecting the satiety scores of Zhanwei capsule users at different times according to the visual analog scale (VAS), analyzing them through the Kaplan-Meier curve, and calculating the satiety change rate of the users; using a radioactive tracer to track the gastric emptying process, and obtaining the concentration of the radioactive tracer in the stomach based on the gastric emptying process based on the gastric emptying curve model, and calculating the gastric emptying time of the radioactive tracer according to the concentration of the radioactive tracer;
[0009] A satiety model is constructed through the rate of change of satiety and gastric emptying time to generate a satiety evaluation coefficient, and the short-term effects after taking the Zhanwei Capsule are analyzed. The changes in food intake and weight change rate of the users are monitored over a long period of time, and the long-term effects after taking the Zhanwei Capsule are analyzed based on the changes in food intake and weight change rate. Based on the short-term and long-term effects after taking the Zhanwei Capsule, fuzzy reasoning is used to determine whether the Zhanwei Capsule taking process needs to be optimized, and a personalized optimization plan is generated by optimizing the frequency, dosage and method of use of the Zhanwei Capsule.
[0010] In a preferred embodiment, the specific process of analyzing and calculating the change rate of satiety of the user by Kaplan-Meier curve is as follows: analyzing by Kaplan-Meier curve, when the change of VAS score is greater than a predetermined critical value, the satiety reaches a significant change, and the VAS score at which the satiety reaches a significant change is recorded; and the time from the start of taking the Zhanwei capsule to the time when the user reaches the predetermined critical value is obtained by the curve; the change rate of satiety of the user is calculated according to the change of VAS score and the time from the start of taking the Zhanwei capsule to the time when the user reaches the predetermined critical value;
[0011] In a preferred embodiment, the specific steps of obtaining the concentration of the radioactive tracer in the stomach based on the gastric emptying process and the gastric emptying curve model are as follows: measuring the concentration of the radioactive tracer in the stomach at regular intervals; plotting the measured radioactive tracer concentration data at different time points into a gastric emptying curve, in which the vertical axis represents the concentration of the tracer and the horizontal axis represents time, reflecting the emptying characteristics of the stomach; fitting a mathematical model of the gastric emptying curve by the nonlinear least squares method to calculate the concentration of the radioactive tracer in the stomach; and calculating the gastric emptying time of the radioactive tracer based on the concentration of the radioactive tracer.
[0012] In a preferred embodiment, the specific process of analyzing the short-term effect after taking Zhanwei Capsule is as follows: according to the satiety assessment coefficient, the short-term effect after taking Zhanwei Capsule is analyzed, and the satiety assessment coefficient is compared with a preset satiety assessment threshold; if the satiety assessment coefficient is greater than the preset satiety assessment threshold, the short-term effect after taking Zhanwei Capsule is good; if the satiety assessment coefficient is less than the preset satiety assessment threshold, the short-term effect after taking Zhanwei Capsule is not good, and the short-term effect after taking Zhanwei Capsule is enhanced by delaying gastric emptying and reducing food intake.
[0013] In a preferred embodiment, the specific process of obtaining the change in food intake is as follows: regularly monitoring the food intake and frequency of the user in different time periods, and calculating the calories consumed before and after taking the medicine within a predetermined time period; calculating the change in food intake for long-term users based on the calories consumed before and after taking the medicine.
[0014] In a preferred embodiment, the specific process of obtaining the weight change rate is as follows: obtaining the weight of the user before and after taking the Zhanwei Capsule, and calculating the weight change within a predetermined time period; calculating the weight change rate of the user based on the weight change and the time period.
[0015] In a preferred embodiment, it is characterized in that the process of analyzing the long-term effect after taking Zhanwei Capsule according to the change in food intake and the change rate of body weight is as follows: a long-term effect evaluation coefficient is generated according to the change in food intake and the change in body weight, and the long-term effect evaluation coefficient is compared with a preset long-term effect evaluation threshold value. If the long-term effect evaluation coefficient is greater than the preset long-term effect evaluation threshold value, the long-term effect after taking Zhanwei Capsule is better; if the long-term effect evaluation coefficient is less than the preset long-term effect evaluation threshold value, the long-term effect after taking Zhanwei Capsule is not good, and the long-term effect after taking Zhanwei Capsule is enhanced by reducing food intake.
[0016] In a preferred embodiment, the short-term effect and long-term effect after taking the Zhanwei Capsule are judged based on fuzzy reasoning whether the Zhanwei Capsule taking process needs to be optimized, and the specific process is as follows:
[0017] The satiety evaluation coefficient and the long-term effect evaluation coefficient are defined as input variables and divided into different fuzzy sets respectively; whether the Zhanwei Capsule taking process needs to be optimized is defined as the output variable and divided into fuzzy sets; fuzzy rules are formulated to describe the influence of the satiety evaluation coefficient and the long-term effect evaluation coefficient on whether the Zhanwei Capsule taking process needs to be optimized; fuzzy reasoning is performed based on the fuzzy rules to determine whether the Zhanwei Capsule taking process needs to be optimized.
[0018] The technical effects and advantages of the multi-dimensional monitoring satiety and stomach-occupying capsule effect evaluation optimization method of the present invention are as follows:
[0019] 1. The present invention can comprehensively evaluate the effect of Zhanwei Capsule through multi-dimensional data monitoring, rather than relying solely on single subjective feedback, thereby increasing the accuracy and comprehensiveness of the evaluation; the method can provide personalized optimization suggestions based on the specific circumstances of different users, so that the effect of Zhanwei Capsule can better meet the needs of each user, and can automatically adjust the usage plan based on real-time data feedback, so that users can obtain the best effect during use; it provides a long-term effect tracking function to help users gradually achieve health management goals, such as weight control, appetite management, etc.; by monitoring the physiological reactions of individuals after using Zhanwei Capsule, it can accurately judge the changes in each user's satiety and its effect on stomach occupancy, thereby providing tailored solutions for the needs of different individuals.
[0020] 2. The present invention can optimize the design and application of capsules by collecting data on satiety and gastric occupancy in real time, such as adjusting the release rate of the capsule, the ratio of ingredients, and the interaction with the stomach; by monitoring and analyzing various data, the effect of the gastric occupancy capsule can be accurately adjusted to avoid excessive gastric occupancy or other side effects while satisfying the sense of fullness, thereby improving its safety and effectiveness; according to the physiological characteristics and feedback of different individuals, the dosage and usage of the capsule can be adjusted in time to avoid excessive satiety or stomach discomfort and reduce the burden on the gastrointestinal tract; through multi-dimensional monitoring, potential adverse reactions can be captured in real time, thereby intervening in advance to avoid serious side effects or discomfort symptoms. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] Figure 1 It is a schematic diagram of the structure of a multi-dimensional monitoring satiety and stomach-occupying capsule effect evaluation optimization method of the present invention. DETAILED DESCRIPTION
[0022] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0023] Embodiment 1, Figure 1 The present invention provides a multi-dimensional monitoring method for satiety and stomach-occupying capsule effect evaluation optimization method.
[0024] S10, collecting the satiety scores of the patients who took the capsule at different times according to the visual analogue scale (VAS), and analyzing them with the Kaplan-Meier curve to calculate the satiety change rate of the patients;
[0025] The visual analogue scale (VAS) was used to measure the degree of satiety, usually a scale of 0-10, where 0 means no satiety at all and 10 means extreme satiety; patients scored their satiety at the initial stage, and after taking the Zhanwei capsule, each subject scored their satiety at the same time intervals;
[0026] The Kaplan-Meier curve was used for analysis. When the VAS score change was greater than a certain predetermined critical value, the satiety was considered to have changed significantly.
[0027] The time from when the user starts taking the Zhanwei capsule to when the predetermined critical value is reached is obtained through the curve.
[0028] The change rate of satiety of the user is calculated based on the change of VAS score and the time from starting to take the Zhanwei capsule to reaching the predetermined critical value. The specific calculation formula is as follows: ; Wherein, B is the satiety change rate, t is the time from the start of taking the stomach capsule to reaching the predetermined critical value, is the change in VAS score, is the VAS score before taking the medicine, It is the VAS score when the satiety reaches a significant change after taking the medicine.
[0029] S20, using a radioactive tracer to track the gastric emptying process, and obtaining the concentration of the radioactive tracer in the stomach based on a gastric emptying curve model according to the gastric emptying process, and calculating the gastric emptying time of the radioactive tracer according to the concentration of the radioactive tracer;
[0030] Radioactive tracers are usually some safe radioactive isotopes that can emit gamma rays (such as chlorine-36, cesium-137, etc.). They are added to liquid or solid food (such as capsules, after-meal food, etc.). After the patient eats the food containing radioactive tracers, a special gamma camera or other radioactive detection equipment is used to regularly monitor the distribution and concentration of the tracers in the stomach, so as to obtain the emptying process of the gastric substances;
[0031] The specific steps for obtaining the concentration of radioactive tracers in the stomach based on the gastric emptying curve model according to the gastric emptying process are as follows:
[0032] During the experiment, the concentration of the tracer in the stomach was recorded at regular intervals, and the activity values of the radioactive tracer in the stomach at different time points were obtained regularly by scanning equipment;
[0033] The radioactivity intensity of the radiotracer in the stomach was measured at each time point, and its concentration was calculated based on the radioactivity intensity;
[0034] The radioactive tracer concentration data measured at different time points are plotted into a gastric emptying curve, with the vertical axis representing the tracer concentration or relative radioactivity intensity and the horizontal axis representing time;
[0035] Typically, the gastric emptying curve shows a rapid emptying phase (early phase) followed by a slower emptying phase (late phase), and the shape of this curve reflects the emptying characteristics of the stomach;
[0036] According to the experimental data, the mathematical model of the gastric emptying curve is fitted by the nonlinear least square method or other numerical fitting methods. The concentration of the radioactive tracer in the stomach is calculated by the fitted mathematical model. The specific calculation formula is as follows: ; In the formula is the concentration of radioactive tracer in the stomach, is the concentration of the radiotracer at the initial time, k is the gastric emptying rate constant, and t is time;
[0037] The gastric emptying time of the radioactive tracer is calculated based on the concentration of the radioactive tracer. The specific calculation formula is as follows: ; In the formula is the gastric emptying time, is the concentration of radioactive tracer in the stomach, is the concentration of the radioactive tracer at the initial time.
[0038] S30, constructing a satiety model through the satiety change rate and gastric emptying time, generating a satiety evaluation coefficient, and analyzing the short-term effects after taking the Zhanwei capsule;
[0039] The satiety change rate and gastric emptying time are used to construct a satiety model, and the specific calculation formula for generating the satiety evaluation coefficient is as follows: ; In the formula, is the satiety assessment coefficient, B is the satiety change rate, is the gastric emptying time, is the satiety assessment constant, greater than 0.
[0040] According to the satiety assessment coefficient, the short-term effect after taking Zhanwei Capsule is analyzed, and the satiety assessment coefficient is compared with the preset satiety assessment threshold. If the satiety assessment coefficient is greater than the preset satiety assessment threshold, the short-term effect after taking Zhanwei Capsule is better. If the satiety assessment coefficient is less than the preset satiety assessment threshold, the short-term effect after taking Zhanwei Capsule is not good. The short-term effect after taking Zhanwei Capsule is enhanced by delaying gastric emptying and reducing food intake.
[0041] S40, long-term monitoring of the food intake and weight change rate of the user, and analyzing the long-term effect of taking the Zhanwei Capsule based on the food intake and weight change rate;
[0042] Regularly monitor the food intake and frequency of the user at different time periods, and calculate the calories consumed before and after taking the medicine within a predetermined time period, and calculate the changes in the food intake of the user based on the calories consumed before and after taking the medicine, wherein the predetermined time period includes a one-month period;
[0043] The specific calculation formula for the change in food intake is as follows: 00%; where H is the change in food intake, The calories you take in at each meal before taking it. Is the calorie intake per meal after taking it, is the number of meals per day before taking the medicine, is the number of meals per day after taking the medicine, T is the predetermined time period in days;
[0044] Obtain the user's weight before and after taking the Zhanwei Capsule, and calculate the weight change within a predetermined time period. Calculate the user's weight change rate based on the weight change and time period. The specific formula is as follows: ; Where L is the weight change rate, T is the predetermined time period, is the weight of the user after taking the Zhanwei capsule. is the user's weight before taking the Zhanwei capsule;
[0045] The long-term effect evaluation coefficient is generated based on the change in food intake and weight change. The specific formula is as follows: ; Where X is the long-term effect evaluation coefficient, H is the change in food intake, and L is the rate of change in body weight. is the weight factor for changes in food intake, is the weight factor for the rate of change of body weight;
[0046] The long-term effect evaluation coefficient is compared and analyzed with the preset long-term effect evaluation threshold. If the long-term effect evaluation coefficient is greater than the preset long-term effect evaluation threshold, the long-term effect after taking Zhanwei Capsule is better. If the long-term effect evaluation coefficient is less than the preset long-term effect evaluation threshold, the long-term effect after taking Zhanwei Capsule is not good. The long-term effect after taking Zhanwei Capsule can be enhanced by reducing food intake.
[0047] S50, judging whether the process of taking the Zhanwei Capsule needs to be optimized based on fuzzy reasoning according to the short-term and long-term effects after taking the Zhanwei Capsule; if the process of taking the Zhanwei Capsule needs to be optimized, generating a personalized optimization plan by optimizing the frequency, dosage and method of use of the Zhanwei Capsule.
[0048] The short-term and long-term effects after taking the Zhanwei Capsule are judged based on fuzzy reasoning whether the Zhanwei Capsule taking process needs to be optimized, and the specific process is as follows:
[0049] Step C1, defining the satiety evaluation coefficient and the long-term effect evaluation coefficient as input variables, and dividing them into different fuzzy sets respectively.
[0050] For example, "Low", "High" for satiety evaluation coefficient, "Low", "High" for long-term effect evaluation coefficient.
[0051] Step C2, defining whether the process of taking the Zhanwei capsule needs to be optimized as an output variable, and dividing it into fuzzy sets, for example, "No", "Yes", for whether the process of taking the Zhanwei capsule needs to be optimized.
[0052] Step C3, formulate a set of fuzzy rules to describe the impact of different input variables on output variables. The definition of rules can be based on professional knowledge or obtained through data analysis and experiments. For example:
[0053] The satiety evaluation coefficient is marked as D, the long-term effect evaluation coefficient is marked as X, and whether the process of taking the Zhanwei capsule needs to be optimized is marked as P.
[0054] Rule 1: If (D is Low) and (X is Low) then (P is Yes)
[0055] Rule 2: If (D is High) and (X is High) then (P is No) ...
[0057] Step C4, performing fuzzy reasoning according to fuzzy rules to determine whether the process of taking the stomach-stomach capsule needs to be optimized.
[0058] It should be noted that the division of fuzzy sets can be adjusted according to actual conditions. For example, although the present embodiment takes three fuzzy sets as examples, in fact, the satiety evaluation coefficient, the long-term effect evaluation coefficient, and whether the stomach capsule taking process needs to be optimized can be divided into more than three sets to facilitate better and more accurate identification.
[0059] Furthermore, for the satiety evaluation coefficient and the long-term effect evaluation coefficient, the threshold value can be set according to the actual situation for judgment; when the satiety evaluation coefficient is higher than the preset satiety evaluation threshold value, it is marked as "High", and when the long-term effect evaluation coefficient is higher than the preset long-term effect evaluation threshold value, it is marked as "High", and so on. I will not go into details here.
[0060] If the process of taking Zhanwei Capsules needs to be optimized, a personalized optimization plan will be generated by optimizing the frequency, dosage and method of use of Zhanwei Capsules.
[0061] The optimization of the frequency of use should take into account the individual's eating habits and gastrointestinal digestion speed:
[0062] Daily use before meals: Usually taking Zhanwei Capsules 30 minutes to 1 hour before meals can help increase satiety and reduce food intake during meals. Generally speaking, it is taken 1-2 times a day, and it is most effective for breakfast and dinner.
[0063] Avoid overdose: Too many capsules may cause stomach discomfort (such as bloating or constipation), so it is recommended to gradually adjust the frequency according to personal constitution, and no more than 3 times.
[0064] Adjust according to the amount of exercise: If you exercise a lot in a day, you may need to take it less frequently to avoid not being able to meet the body's energy needs due to reducing food intake.
[0065] Dosage is a key factor affecting the effect of the stomach capsule. Too high a dose may cause side effects, while too low a dose may not have a significant effect. The following points should be considered to optimize the dose:
[0066] Starting dose: When you first start, it is recommended to start with a small dose, such as 1 capsule each time (depending on the specific product) and observe your body's reaction.
[0067] Gradually adjust: Depending on personal response, the dose can be gradually increased. The common dosage range is generally 2 capsules (about 1-2 grams) each time, but it is recommended to follow the package instructions or consult a doctor.
[0068] Reasonable use can enhance the effect of Zhanwei Capsule and reduce side effects:
[0069] 30 minutes before meals: Most stomach-spanning capsules are recommended to be taken half an hour before meals, so that they have enough time to expand and occupy space in the stomach.
[0070] Use with water: When using Zhanwei capsules, a large amount of water (usually about 200-300 ml) is required to help the capsules swell and increase satiety, otherwise, the capsules may not work optimally.
[0071] Avoid using with other drugs: Zhanwei Capsules may interact with certain drugs (such as antibiotics, hypoglycemic drugs, etc.), so it is recommended to take other drugs at least 1 hour apart.
[0072] The above formulas are all dimensionless and numerical calculations. The formula is a formula for the most recent real situation obtained by collecting a large amount of data and performing software simulation. The preset parameters in the formula are set by technicians in this field according to actual conditions.
[0073] The above embodiments may be implemented in whole or in part by software, hardware, firmware or any other combination. When implemented by software, the above embodiments may be implemented in whole or in part in the form of a computer program product.
[0074] Those of ordinary skill in the art will appreciate that the modules and algorithm steps of each example described in conjunction with the embodiments disclosed herein can be implemented in electronic hardware, or a combination of computer software and electronic hardware. Whether these functions are performed in hardware or software depends on the specific application and design constraints of the technical solution. Professional and technical personnel can use different methods to implement the described functions for each specific application, but such implementation should not be considered to be beyond the scope of this application.
[0075] In addition, each functional module in each embodiment of the present application may be integrated into one processing module, or each module may exist physically separately, or two or more modules may be integrated into one module.
[0076] The above is only a specific implementation of the present application, but the protection scope of the present application is not limited thereto. Any person skilled in the art who is familiar with the present technical field can easily think of changes or substitutions within the technical scope disclosed in the present application, which should be included in the protection scope of the present application. Therefore, the protection scope of the present application should be based on the protection scope of the claims.
[0077] Finally: The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.
Claims
1. A multi-dimensional monitoring method for satiety and stomach-occupying capsule effect evaluation optimization, characterized in that: The following steps are involved: The scores of satiety based on the visual analogue scale (VAS) were collected from the patients who took the capsule at different times, and the results were analyzed by Kaplan-Meier curve to calculate the change rate of satiety of the patients. Using a radioactive tracer to track the gastric emptying process, and obtaining the concentration of the radioactive tracer in the stomach based on the gastric emptying curve model according to the gastric emptying process, and calculating the gastric emptying time of the radioactive tracer according to the concentration of the radioactive tracer; A satiety model was constructed through the satiety change rate and gastric emptying time to generate a satiety evaluation coefficient, and the short-term effects after taking the Zhanwei capsule were analyzed; Long-term monitoring of the food intake and weight change rate of the users, and analysis of the long-term effects of taking the Zhanwei Capsule based on the food intake and weight change rate; According to the short-term and long-term effects after taking Zhanwei Capsules, fuzzy reasoning is used to determine whether the process of taking Zhanwei Capsules needs to be optimized, and a personalized optimization plan is generated by optimizing the frequency, dosage and method of use of Zhanwei Capsules.
2. A multi-dimensional monitoring satiety and stomach capsule effect evaluation optimization method according to claim 1, characterized in that: The specific process of analyzing and calculating the change rate of satiety of the user through the Kaplan-Meier curve is as follows: The Kaplan-Meier curve was used for analysis. When the VAS score change was greater than the predetermined critical value, the satiety achieved a significant change, and the VAS score at which the satiety achieved a significant change was recorded. The time from when the user starts taking the Zhanwei capsule to when the predetermined critical value is reached is obtained through the curve; The change rate of satiety of the users was calculated based on the change of VAS score and the time from the start of taking the Zhanwei capsule to reaching the predetermined critical value; The specific calculation formula of the satiety change rate is as follows: ; Wherein, B is the satiety change rate, t is the time from the start of taking the stomach capsule to reaching the predetermined critical value, is the change in VAS score, is the VAS score before taking the medicine, It is the VAS score when the satiety reaches a significant change after taking the medicine.
3. A multi-dimensional monitoring satiety and stomach capsule effect evaluation optimization method according to claim 2, characterized in that: The specific steps of obtaining the concentration of the radioactive tracer in the stomach based on the gastric emptying curve model according to the gastric emptying process are as follows: The concentration of radioactive tracer in the stomach is measured at regular intervals; The radioactive tracer concentration data measured at different time points are plotted into a gastric emptying curve, with the vertical axis representing the tracer concentration and the horizontal axis representing time, reflecting the emptying characteristics of the stomach; The mathematical model of gastric emptying curve was fitted by nonlinear least square method to calculate the concentration of radioactive tracer in the stomach; The gastric emptying time of the radioactive tracer was calculated based on the concentration of the radioactive tracer.
4. A multi-dimensional monitoring satiety and stomach capsule effect evaluation optimization method according to claim 3, characterized in that: The specific calculation formula for the intragastric radioactive tracer concentration is as follows: ; In the formula is the concentration of radioactive tracer in the stomach, is the concentration of the radiotracer at the initial time, k is the gastric emptying rate constant, and t is time; The specific calculation formula of the gastric emptying time is as follows: ; In the formula is the gastric emptying time, is the concentration of radioactive tracer in the stomach, is the concentration of the radioactive tracer at the initial time.
5. A multi-dimensional monitoring satiety and stomach capsule effect evaluation optimization method according to claim 4, characterized in that: The satiety model is constructed by using the satiety change rate and gastric emptying time to generate the specific calculation formula for the satiety evaluation coefficient as follows: ; In the formula, is the satiety assessment coefficient, B is the satiety change rate, is the gastric emptying time, is the satiety assessment constant, greater than 0.
6. A multi-dimensional monitoring satiety and stomach capsule effect evaluation optimization method according to claim 5, characterized in that: The specific process of analyzing the short-term effects after taking Zhanwei Capsules is as follows: According to the satiety evaluation coefficient, the short-term effect after taking Zhanwei Capsule was analyzed, and the satiety evaluation coefficient was compared with the preset satiety evaluation threshold; If the satiety assessment coefficient is greater than the preset satiety assessment threshold, the short-term effect after taking the Zhanwei capsule is better; If the satiety assessment coefficient is less than the preset satiety assessment threshold, the short-term effect after taking the Zhanwei Capsule is poor. The short-term effect after taking the Zhanwei Capsule can be enhanced by delaying gastric emptying and reducing food intake.
7. A multi-dimensional monitoring satiety and stomach capsule effect evaluation optimization method according to claim 6, characterized in that: The specific process of obtaining the change in food intake is as follows: Regularly monitor the amount and frequency of food intake of the user at different time periods, and calculate the calories consumed before and after taking the medicine within a predetermined time period; Changes in food intake for long-term users were calculated based on pre- and post-dose calories intake; The specific calculation formula for the change in food intake is as follows: 00%; where H is the change in food intake, The calories you take in at each meal before taking it. Is the calorie intake per meal after taking it, is the number of meals per day before taking the medicine, is the number of meals per day after taking the drug, and T is the predetermined time period in days.
8. A multi-dimensional monitoring satiety and stomach-occupying capsule effect evaluation optimization method according to claim 7, characterized in that: The specific process of obtaining the weight change rate is as follows: Obtaining the body weight of the user before and after taking the Zhanwei capsule, and calculating the weight change within a predetermined time period; The weight change rate of the user is calculated based on weight change and time period. The specific formula is as follows: ; Where L is the weight change rate, T is the predetermined time period, is the weight of the user after taking the Zhanwei capsule. It is the weight of the user before taking the capsule.
9. A multi-dimensional monitoring satiety and stomach capsule effect evaluation optimization method according to claim 7, characterized in that: The long-term effect of taking Zhanwei Capsule was analyzed based on the change of food intake and weight change rate as follows: The long-term effect evaluation coefficient is generated based on the change in food intake and weight change. The specific formula is as follows: ; where X is the long-term effect evaluation coefficient, H is the change in food intake, and L is the rate of change in body weight. is the weight factor for changes in food intake, is the weight factor for the rate of change of body weight; Compare and analyze the long-term effect evaluation coefficient with the preset long-term effect evaluation threshold. If the long-term effect evaluation coefficient is greater than the preset long-term effect evaluation threshold, the long-term effect after taking the Zhanwei capsule is better. If the long-term effect evaluation coefficient is less than the preset long-term effect evaluation threshold, the long-term effect after taking the Zhanwei Capsule is not good, and the long-term effect after taking the Zhanwei Capsule can be enhanced by reducing food intake.
10. The method for optimizing the evaluation of satiety and stomach-occupying capsule effect by multi-dimensional monitoring according to claim 7, characterized in that: The short-term and long-term effects after taking the Zhanwei Capsule are judged based on fuzzy reasoning whether the Zhanwei Capsule taking process needs to be optimized, and the specific process is as follows: The satiety evaluation coefficient and the long-term effect evaluation coefficient are defined as input variables, and they are divided into different fuzzy sets respectively; Whether the process of taking the stomach-sucking capsule needs to be optimized is defined as the output variable, and it is divided into fuzzy sets; Formulate fuzzy rules to describe the influence of satiety evaluation coefficient and long-term effect evaluation coefficient on whether the process of taking Zhanwei capsule needs to be optimized; Fuzzy reasoning is performed based on fuzzy rules to determine whether the process of taking the Zhanwei capsule needs to be optimized.
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