A pediatric intelligent atomization method and system

Abstract

The present invention discloses an intelligent atomization method and system for pediatrics, and relates to the field of intelligent atomization technology. The intelligent atomization method for pediatrics obtains physiological state data before a child to be treated undergoes atomization treatment, and the physiological state data includes disease state data and respiratory state data; and performs data analysis respectively to obtain the disease state index and respiratory state index of the child to be treated, and performs comprehensive analysis to obtain the comprehensive atomization treatment index of the child to be treated; and takes corresponding preliminary atomization treatment measures based on the comprehensive atomization treatment index of the child to be treated. The present invention obtains atomization treatment data in real time when atomization is performed on the child to be treated, performs monitoring and analysis, and optimizes and adjusts preliminary atomization treatment measures based on the monitoring and analysis results, thereby timely discovering problems that occur during the treatment process, and adjusting preliminary treatment measures according to the data, thereby ensuring the safety and comfort of the child.

Description

Technical Field

[0001] The present invention relates to the field of intelligent atomization technology, and in particular to an intelligent atomization method and system for pediatrics. Background Art

[0002] With the continuous advancement of modern medical technology, atomization therapy has become an important means of treating respiratory diseases, especially in the field of pediatric internal medicine. Atomization therapy is widely used in the treatment of airway diseases, pneumonia, bronchitis, asthma and other diseases. In recent years, with the development of sensing technology, artificial intelligence technology and intelligent medical equipment, intelligent atomization treatment systems have emerged. Intelligent atomization can adjust treatment parameters according to the specific needs of patients to provide personalized and accurate treatment plans. However, intelligent atomization still faces problems such as insufficient real-time monitoring accuracy, poor adaptability, and lack of optimized design for children. Children are more sensitive to treatment than adults. Therefore, how to achieve personalized intelligent atomization treatment plans for different diseases has become a technical problem that needs to be solved urgently.

[0003] Prior art, such as a patent application with announcement number: CN109107006B, discloses an intelligent atomizer and its use method and atomization management system, including: atomizer body, an interaction module, a control module and a display module; the interaction module is used to output a first voice prompt information when receiving a voice start command, and send a start signal to the control module to make it pop out the atomization cup in the atomizer body; when receiving the voice atomization information, repeat the voice atomization information, convert it into text atomization information and display it through the display module; when receiving the voice atomization instruction, send the text atomization information and the time when the voice atomization information is received as the atomization time to at least one external intelligent terminal, and send an atomization signal to the control module to make it detect whether the atomization cup is in place, and if so, control the atomization of the atomizer body, wherein the voice atomization information includes: user information, drug name and drug dosage. This solution can reduce the fear of children when atomizing.

[0004] Based on the above solution, it is found that the limitations of the existing technology include at least the following problems. First, the existing technology lacks a comprehensive treatment evaluation of the specific symptoms of child patients, which leads to the treatment plan not being targeted, and then leads to poor treatment effect. Second, during the atomization treatment process, children are more sensitive to treatment than adults. The existing technology fails to make dynamic adjustments based on real-time treatment data, resulting in the treatment plan being not accurate enough and difficult to respond to the patient's physical changes, thereby affecting the effectiveness of the treatment, and then it is difficult to effectively improve the treatment effect. Summary of the invention

[0005] In view of the deficiencies of the prior art, the present invention provides an intelligent atomization method and system for pediatrics, which solves the problems that the prior art lacks comprehensive treatment evaluation of the specific symptoms of child patients and fails to make dynamic adjustments based on real-time treatment data, thereby affecting the effectiveness of treatment.

[0006] To achieve the above objectives, the present invention is implemented through the following technical solutions: an intelligent nebulization method for pediatrics, comprising the following steps: before the child to be treated undergoes nebulization treatment, obtaining physiological state data, the physiological state data including disease state data and respiratory state data; performing data analysis on the physiological state data of the child to be treated, respectively, obtaining the disease state index and respiratory state index of the child to be treated, and performing comprehensive analysis to obtain the comprehensive nebulization treatment index of the child to be treated; taking corresponding preliminary nebulization treatment measures based on the comprehensive nebulization treatment index of the child to be treated, and when the child to be treated undergoes nebulization, obtaining nebulization treatment data in real time, performing monitoring and analysis, and optimizing and adjusting the preliminary nebulization treatment measures based on the monitoring and analysis results; wherein, the specific formula for calculating the comprehensive nebulization treatment index of the child to be treated is as follows: ;in, is the comprehensive aerosol therapeutic index of the child to be treated. is the disease status index of the child to be treated, is the disease coefficient stored in the database, is the respiratory status index of the child to be treated, is the breathing coefficient stored in the database, is the interaction coefficient stored in the database.

[0007] Furthermore, the disease status data include blood oxygen saturation value, body temperature value, reactive protein level value, arterial blood gas index, and oxygenation index; the respiratory status data include tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value; and the nebulization treatment data include nebulized drug deposition rate value, airway mucus level value, ventilation ratio value, nebulized particle diameter value, nebulized drug concentration value, and drug concentration gradient index.

[0008] Furthermore, the specific steps for obtaining the disease state index of the child to be treated are as follows: obtain the reference value of oxygen partial pressure and carbon dioxide partial pressure of the child to be treated, and perform standardization processing, and perform weighted processing based on the reference value of oxygen partial pressure and carbon dioxide partial pressure of the child to be treated after standardization to obtain the reference index of arterial blood gas analysis of the child to be treated; and obtain the reference value of blood oxygen saturation and body temperature of the child to be treated, and perform comprehensive analysis based on the blood oxygen saturation value, body temperature value and arterial blood gas index to obtain the infection index of the child to be treated; standardize the infection index, reactive protein level value and oxygenation index of the child to be treated; and perform comprehensive analysis on the infection index, reactive protein level value and oxygenation index of the child to be treated after standardization to obtain the disease state index of the child to be treated.

[0009] Furthermore, the specific formula for calculating the infection index and disease state index of the child to be treated is as follows: ;in, is the infection index of children to be treated, is the blood oxygen saturation value of the child to be treated, is the reference value of blood oxygen saturation for children to be treated, is the blood oxygen coefficient stored in the database, is the temperature of the child to be treated, is the reference value of the temperature of the child to be treated, is the temperature coefficient stored in the database, is the arterial blood gas index of the child to be treated, is the arterial blood gas reference index for children to be treated, is the blood gas coefficient stored in the database, is the disease status index of the child to be treated, is the infection index of the children to be treated after standardized treatment. is the infection coefficient stored in the database, is the level of protein in the children to be treated after standardized treatment. is the protein coefficient stored in the database, is the oxygenation index of the child to be treated after standardized treatment. is the oxygenation coefficient stored in the database, , is a natural constant.

[0010] Furthermore, the specific steps for obtaining the respiratory state index of the child to be treated are as follows: obtain the tidal volume reference value, respiratory ratio reference value, gas exchange frequency reference value, and respiratory airway resistance reference value of the child to be treated, and conduct a comprehensive analysis based on the tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value to obtain the initial respiratory state index of the child to be treated; normalize the tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value of the child to be treated; and conduct a comprehensive analysis of the tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value of the child to be treated after the normalization to obtain the respiratory interaction factor of the child to be treated; and conduct a comprehensive analysis of the initial respiratory state index and the respiratory interaction factor of the child to be treated to obtain the respiratory state index of the child to be treated.

[0011] Furthermore, the specific formulas for calculating the initial respiratory state index, respiratory interaction factor, and respiratory state index of the child to be treated are as follows: ;in, is the initial respiratory status index of the child to be treated, , , , They are the tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value of the child to be treated. , , , These are the tidal volume reference value, respiratory ratio reference value, gas exchange frequency reference value, and respiratory airway resistance reference value of the child to be treated. , , , They are the tidal coefficient, respiratory ratio coefficient, exchange coefficient, and airway resistance coefficient stored in the database. , is the respiratory interaction factor for the child to be treated, , , , They are the tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value of the child to be treated after normalization. , , , They are the tidal interaction coefficient, respiratory ratio interaction coefficient, exchange interaction coefficient, and airway resistance interaction coefficient stored in the database. is the respiratory status index of the child to be treated, , They are the initial coefficient and interaction coefficient stored in the database, , is a natural constant.

[0012] Furthermore, the specific steps for taking corresponding preliminary nebulization treatment measures based on the comprehensive nebulization treatment index of the child to be treated are as follows: the comprehensive nebulization treatment index of the child to be treated is judged and analyzed with the preset comprehensive nebulization treatment index threshold; if the comprehensive nebulization treatment index of the child to be treated is lower than or equal to the preset comprehensive nebulization treatment index threshold, the first preliminary nebulization treatment measure is taken; if the comprehensive nebulization treatment index of the child to be treated is higher than the preset comprehensive nebulization treatment index threshold, the second preliminary nebulization treatment measure is taken.

[0013] Furthermore, when nebulization is performed on the child to be treated, the nebulization treatment data is obtained in real time, monitored and analyzed, and the specific steps for optimizing and adjusting the initial nebulization treatment measures based on the monitoring and analysis results are as follows: obtain the reference value of nebulized drug deposition rate, airway mucus level, ventilation ratio, nebulized particle diameter, and nebulized drug concentration for the child to be treated under the initial nebulization treatment measures; conduct a comprehensive analysis of the reference value of nebulized drug deposition rate, airway mucus level, ventilation ratio, including nebulized drug deposition rate value, airway mucus level value, and ventilation ratio value for the child to be treated under the initial nebulization treatment measures to obtain the drug delivery index of the child to be treated under the initial nebulization treatment measures; obtain the reference value of nebulized particle diameter, nebulized drug concentration, and airway mucus level for the child to be treated under the initial nebulization treatment measures; The drug concentration reference value, aerosol particle diameter value, aerosol drug concentration value, and drug concentration gradient index are standardized; and the aerosol particle diameter reference value, aerosol drug concentration reference value, aerosol particle diameter value, aerosol drug concentration value, and drug concentration gradient index of the children to be treated under the initial aerosol treatment measures after standardization are comprehensively analyzed to obtain the drug absorption index of the children to be treated under the initial aerosol treatment measures; the drug delivery index and drug absorption index of the children to be treated under the initial aerosol treatment measures are comprehensively analyzed to obtain the therapeutic index of the children to be treated under the initial aerosol treatment measures; and the therapeutic index of the children to be treated under the initial aerosol treatment measures is compared and analyzed with the preset therapeutic index threshold, and corresponding aerosol treatment optimization and adjustment measures are taken based on the comparison and analysis results.

[0014] Furthermore, the specific formulas for calculating the drug delivery index, drug absorption index, and therapeutic index of the child to be treated under the initial aerosol treatment measures are as follows: ;in, The drug delivery index for children to be treated under initial nebulized treatment measures, , , They are the aerosol drug deposition rate, airway mucus level, and ventilation ratio of the children to be treated under the initial aerosol treatment measures. , , These are the reference values ​​for the aerosolized drug deposition rate, airway mucus level, and ventilation ratio of the children to be treated under the initial aerosolized treatment measures. , , They are the drug deposition coefficient, airway mucus coefficient, and ventilation coefficient stored in the data, respectively. , is the drug absorption index of the children to be treated under the initial nebulization treatment measures, , , They are the aerosol particle diameter value, aerosol drug concentration value, and drug concentration gradient index of the children to be treated under the initial aerosol treatment measures after standardized treatment. , They are the reference values ​​of aerosol particle diameter and aerosol drug concentration for children to be treated under the initial aerosol treatment measures after standardized treatment. , , They are the particle diameter coefficient, atomization concentration coefficient, and gradient coefficient stored in the data, respectively. , The therapeutic index of the child to be treated under the initial nebulization treatment measures, , They are the transport coefficient and treatment coefficient stored in the data, , is a natural constant.

[0015] A pediatric intelligent nebulization system comprises: a data acquisition module, a data analysis module, a comprehensive analysis module, a preliminary nebulization module, and a monitoring and optimization module; the data acquisition module is used to acquire physiological state data before a nebulization treatment is performed on a child to be treated, wherein the physiological state data includes disease state data and respiratory state data; the data analysis module is used to respectively analyze the physiological state data of the child to be treated to obtain a disease state index and a respiratory state index of the child to be treated; the comprehensive analysis module is used to perform a comprehensive analysis on the disease state index and the respiratory state index of the child to be treated to obtain a comprehensive nebulization treatment index of the child to be treated; the preliminary nebulization module is used to take corresponding preliminary nebulization treatment measures based on the comprehensive nebulization treatment index of the child to be treated; the monitoring and optimization module is used to acquire nebulization treatment data in real time while treating the child to be treated, and to perform monitoring and analysis, and to optimize and adjust the preliminary nebulization treatment measures based on the monitoring and analysis results.

[0016] The present invention has the following beneficial effects:

[0017] (1) The pediatric intelligent nebulization method determines the initial treatment measures based on the child's comprehensive nebulization treatment index, thereby realizing a personalized treatment plan. Before treatment, detailed data analysis of the disease status and respiratory status is performed to ensure that the treatment plan can be designed according to the child's specific condition. For different degrees of illness, the treatment plan is designed to meet the actual needs of the child, thereby effectively improving the treatment effect.

[0018] (2) The intelligent nebulization method for pediatric internal medicine can promptly detect problems that arise during the treatment process through real-time feedback analysis of treatment data during the nebulization treatment process, and adjust the initial treatment measures based on the data to avoid over-treatment or insufficient treatment, thereby maximizing treatment safety. Children are more sensitive to treatment than adults, which effectively reduces the risks during the treatment process.

[0019] (3) This pediatric intelligent nebulization method compares and analyzes the therapeutic index with the preset therapeutic index threshold, and optimizes and adjusts the initial measures of nebulization treatment based on the results, thereby effectively avoiding overtreatment and reducing the side effects experienced by children, thereby ensuring the safety and comfort of children.

[0020] (4) The pediatric intelligent nebulization system, through the efficient operation of the data acquisition module and the data analysis module, enables the physiological status data to be quickly and accurately converted into the index of the disease condition and respiratory status, generates a comprehensive nebulization treatment index, and takes corresponding treatment measures based on the child's comprehensive nebulization treatment index, thereby reducing the possibility of over- or under-treatment, and shortening the treatment cycle while ensuring the efficacy. At the same time, the real-time monitoring and optimization functions of the monitoring optimization module can make optimizations at any time during the treatment process, so as to avoid duplication of treatment or waste of resources, thereby making the treatment process streamlined and efficient, thereby improving the hospital's treatment efficiency.

[0021] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 The present invention is a flow chart of an intelligent atomization method for pediatrics.

[0023] Figure 2 The present invention is a flowchart of the steps of obtaining the disease state index of a child to be treated in a pediatric intelligent atomization method.

[0024] Figure 3 This is a block diagram of an intelligent nebulization system for pediatrics of the present invention. DETAILED DESCRIPTION

[0025] The overall idea of ​​the problem in the embodiment of this application is as follows:

[0026] Before nebulization treatment is performed on the child to be treated, the physiological state data of the child to be treated, including disease state data and respiratory state data, are first collected, and the data are analyzed separately to obtain the disease state index and respiratory state index of the child to be treated, and a comprehensive analysis is performed to obtain the comprehensive nebulization treatment index of the child to be treated, and corresponding preliminary nebulization treatment measures are taken based on the comprehensive nebulization treatment index of the child to be treated, and when nebulization is performed on the child to be treated, the nebulization treatment data is obtained in real time, monitored and analyzed, and the preliminary nebulization treatment measures are optimized and adjusted based on the monitoring and analysis results.

[0027] See also Figure 1 The embodiment of the present invention provides a technical solution: an intelligent nebulization method for pediatrics, comprising the following steps: obtaining physiological state data before a child to be treated undergoes nebulization treatment (e.g., a child suffering from pneumonia needs nebulization treatment), wherein the physiological state data includes disease state data and respiratory state data; performing data analysis on the physiological state data of the child to be treated to obtain the disease state index and respiratory state index of the child to be treated, and performing comprehensive analysis to obtain the comprehensive nebulization treatment index of the child to be treated; taking corresponding preliminary nebulization treatment measures based on the comprehensive nebulization treatment index of the child to be treated, and obtaining nebulization treatment data in real time when the child to be treated undergoes nebulization, performing monitoring and analysis, and optimizing and adjusting the preliminary nebulization treatment measures based on the monitoring and analysis results; wherein, the specific formula for calculating the comprehensive nebulization treatment index of the child to be treated is as follows: ;in, is the comprehensive aerosol therapeutic index of the child to be treated. is the disease status index of the child to be treated, is the disease coefficient stored in the database, is the respiratory status index of the child to be treated, is the breathing coefficient stored in the database, is the interaction coefficient stored in the database.

[0028] It should be explained that the formula This item is used to adjust the superimposed effect of the disease state index and respiratory state index of the child to be treated to prevent the comprehensive nebulization treatment index from being too high or too low.

[0029] , , It can be obtained through the following steps: using the historical monitoring data of the child to be treated, combined with indicators such as the disease state index and the respiratory state index, statistical regression analysis is performed to quantify the specific impact of each factor on the comprehensive nebulization treatment index, thereby fitting the initial weight value; secondly, using the sensitivity analysis method, adjust the value range of each coefficient, observe its impact on the evaluation results of the comprehensive nebulization treatment index, ensure the stability and rationality of the model, and based on the characteristics and actual situation of the child to be treated, correct and optimize the preliminary fitting coefficients, and finally determine the coefficient value applicable to the child to be treated.

[0030] Disease status data include blood oxygen saturation value, body temperature value, (C) reactive protein level value, arterial blood gas index, and oxygenation index. Respiratory status data include tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value. Nebulization treatment data include nebulized drug deposition rate value, airway mucus level value, ventilation ratio value, nebulized particle diameter value, nebulized drug concentration value, and drug concentration gradient index.

[0031] Among them, the reactive protein level value is an acute phase reactive protein in the body, and its level will increase significantly in conditions of inflammation, infection, tissue damage, etc. The reactive protein level value can be obtained through sampling method, that is, fingertip blood collection and measurement using a portable blood analyzer, and is used to reflect the severity of lung infection.

[0032] The arterial blood gas index is the level of oxygen and carbon dioxide in arterial blood, which can be obtained through the following steps: obtaining the oxygen partial pressure value (i.e. the oxygen content in the blood) and the carbon dioxide partial pressure value (the carbon dioxide content in the blood), and performing standardization, and performing weighted processing based on the standardized processing results to obtain the blood gas index. The oxygen partial pressure value and the carbon dioxide partial pressure value can both be obtained through the sampling method, that is, sampling the radial artery and measuring it with a portable blood gas analyzer, and the arterial blood gas index is used to reflect the ventilation function of the lungs.

[0033] The oxygenation index is the oxygenation capacity of the lungs, which can be obtained through the following steps: obtaining the oxygen concentration value (that is, the oxygen concentration in the breathing gas, such as 21% oxygen in indoor air, then the oxygen concentration is 21%), the carbon dioxide partial pressure value (the carbon dioxide content in the blood), and standardizing them, and performing weighted processing based on the standardized processing results to obtain the oxygenation index. The oxygen concentration value can be obtained through a gas analyzer, and the oxygenation index is used to reflect the severity of lung infection.

[0034] The tidal volume value is the average of the amount of gas inhaled during several breaths, and the amount of gas inhaled during each breath can be obtained by the airflow sensor. The tidal volume value is used to reflect the patency of the airway.

[0035] The breathing ratio is the average of the ratios of several inhalation durations to exhalation durations, and each inhalation duration and exhalation duration can be obtained by a respiratory airflow sensor. The breathing ratio is used to reflect whether there is airway obstruction.

[0036] The gas exchange frequency value is the number of gas exchanges per unit time, which can be obtained through a gas exchange analyzer (that is, combining the lung airflow and the changes in oxygen and carbon dioxide concentrations, and using the algorithm inside the device to derive the gas exchange frequency). The gas exchange frequency value is used to reflect the efficiency of gas exchange, that is, the soundness of respiratory function.

[0037] The respiratory airway resistance value refers to the resistance encountered by air when flowing through the respiratory tract. It can be measured by a pulmonary function tester. The respiratory airway resistance value is used to reflect the patency of the airway.

[0038] The aerosolized drug deposition rate value is the ratio of the aerosolized drug deposition in the airway and lung. The airway deposition amount and lung deposition can be obtained by a SPECT scanner (i.e., labeling the drug with a radioactive isotope and scanning it with a scanner to monitor the deposition of the radioactive marker in the airway), which is used to reflect the delivery efficiency of the aerosolized drug.

[0039] The airway mucus level value is the viscosity of the mucus layer in the airway, which can be obtained by a viscosity sensor and is used to reflect the delivery efficiency of the nebulized drug.

[0040] The ventilation ratio is the ratio of lung ventilation (the total amount of air entering and leaving the lungs per unit time) to blood perfusion (the amount of blood flowing through the pulmonary capillaries per unit time). The ventilation volume can be obtained through exhaled gas analysis, and the blood perfusion volume can be obtained through a PET scanner. The ventilation ratio is used to reflect the delivery efficiency of aerosolized drugs.

[0041] The aerosolized drug concentration value is the concentration of the drug diluted into the air during the aerosolization process, which can be obtained by an aerosol concentration meter and is used to reflect the drug absorption effect.

[0042] The atomized particle diameter value is the average diameter of each particle of the drug during the atomization process, which can be obtained by a laser particle counter and is used to reflect the absorption effect of the drug.

[0043] The drug concentration gradient index is the concentration distribution of the drug at multiple monitoring points in the airway, and the concentration of the drug at multiple monitoring points is processed by standard deviation, and the standard deviation processing result is the drug concentration gradient index, wherein the concentration of the drug at each monitoring point in the airway can be obtained by a micro-electrochemical sensor, which is used to reflect the absorption effect.

[0044] Specifically, Figure 2As shown in the figure, the specific steps to obtain the disease state index of the child to be treated are as follows: Obtain the reference values of partial pressure of oxygen and partial pressure of carbon dioxide of the child to be treated, and perform standardization processing (i.e., unit removal processing). Based on the reference values of partial pressure of oxygen and partial pressure of carbon dioxide of the child to be treated after standardization processing, perform weighted processing to obtain the reference index of arterial blood gas analysis of the child to be treated; and obtain the reference value of blood oxygen saturation and reference value of body temperature of the child to be treated, and at the same time, perform comprehensive analysis by combining the blood oxygen saturation value, body temperature value, and arterial blood gas index to obtain the infection index of the child to be treated; perform standardization processing (i.e., unit removal processing) on the infection index, C-reactive protein level value, and oxygenation index of the child to be treated; and perform comprehensive analysis on the infection index, C-reactive protein level value, and oxygenation index of the child to be treated after standardization processing to obtain the disease state index of the child to be treated.

[0045] Among them, the reference values of partial pressure of oxygen, partial pressure of carbon dioxide, blood oxygen saturation, and body temperature of the child to be treated can all be obtained through biomedical literature databases (such as: PubMed, UpToDate, ClinicalKey).

[0046] The specific formulas for calculating the infection index and disease state index of the child to be treated are as follows: ; among them, is the infection index of the child to be treated, is the blood oxygen saturation value of the child to be treated, is the reference value of blood oxygen saturation of the child to be treated, is the blood oxygen coefficient stored in the database, is the body temperature value of the child to be treated, is the reference value of body temperature of the child to be treated, is the temperature coefficient stored in the database, is the arterial blood gas index of the child to be treated, is the reference index of arterial blood gas of the child to be treated, is the blood gas coefficient stored in the database, is the disease state index of the child to be treated, is the infection index of the child to be treated after standardization processing, is the infection coefficient stored in the database, is the C-reactive protein level value of the child to be treated after standardization processing, is the protein coefficient stored in the database, is the oxygenation index of the child to be treated after standardization processing, is the oxygenation coefficient stored in the database, , is the natural constant, and its value is 2.71 in this embodiment.

[0047] It needs to be explained that , , It can be obtained through the following steps: First, based on the historical monitoring data of the child to be treated, the initial impact weight of each variable (such as blood oxygen saturation value, body temperature value, arterial blood gas index, etc.) on the ecological health index is determined through statistical regression analysis. Then, the range of coefficients is adjusted using the sensitivity analysis method to evaluate the stability and applicability of these parameters to the formula output. Next, the weights are further fitted through model optimization (such as multi-objective optimization) to ensure that the formula can accurately reflect the actual disease status index. The coefficients are fine-tuned based on the characteristics of different children to ensure that they are suitable for the specific disease status needs of children.

[0048] and , , It can be obtained through the following steps: read the infection index, reactive protein level value, and oxygenation index of the child to be treated after standardized treatment, and perform sum analysis to obtain the sum of the condition, and perform proportion analysis on the infection index, reactive protein level value, and oxygenation index of the child to be treated after standardized treatment and the sum of the condition, respectively, and use the proportion analysis results as the corresponding coefficients.

[0049] In this implementation scheme, by calculating the disease state index of the child to be treated, the severity of the disease can be quantitatively assessed according to the child's specific pathological state, which helps doctors to formulate treatment plans according to the child's specific situation, so as to achieve precise treatment. Secondly, by comprehensively analyzing multiple key indicators such as infection index, reactive protein level and oxygenation index, a more comprehensive assessment of the disease can be made to avoid missing important factors, thereby providing more scientific data support for the formulation of treatment plans and making more accurate judgments. At the same time, through standardization and sensitivity analysis methods, the deviations and errors between different variables can be reduced, thereby ensuring consistency in data processing, thereby improving the controllability of the treatment plan. Finally, based on the coefficient adjustment of multi-objective optimization, the model can continuously adapt to new patient data and treatment needs during long-term use, further improve its accuracy and effectiveness, and can continuously improve the accuracy of the treatment plan as data accumulates.

[0050] Specifically, the specific steps to obtain the respiratory state index of the child to be treated are as follows: obtain the tidal volume reference value, respiratory ratio reference value, gas exchange frequency reference value, and respiratory airway resistance reference value of the child to be treated, and conduct a comprehensive analysis based on the tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value to obtain the initial respiratory state index of the child to be treated; normalize the tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value of the child to be treated (i.e., remove the unit); and conduct a comprehensive analysis of the tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value of the child to be treated after the normalization to obtain the respiratory interaction factor of the child to be treated; and conduct a comprehensive analysis of the initial respiratory state index and the respiratory interaction factor of the child to be treated to obtain the respiratory state index of the child to be treated.

[0051] Among them, the reference values ​​of tidal volume, respiratory ratio, gas exchange frequency, and respiratory airway resistance of the children to be treated can all be obtained through biomedical literature databases (such as PubMed, UpToDate, and ClinicalKey).

[0052] The specific formulas for calculating the initial respiratory state index, respiratory interaction factor, and respiratory state index of the child to be treated are as follows: ;in, is the initial respiratory status index of the child to be treated, is the tidal volume value of the child to be treated, is the reference value of tidal volume for children to be treated, is the moisture coefficient stored in the database, is the respiratory ratio of the child to be treated, is the reference value of the respiratory ratio for the child to be treated, is the moisture coefficient stored in the database, is the gas exchange frequency value of the child to be treated, is the reference value of gas exchange frequency for children to be treated, is the exchange coefficient stored in the database, is the airway resistance value of the child to be treated, is the reference value of airway resistance for the child to be treated. is the airway resistance coefficient stored in the database, , is the respiratory interaction factor for the child to be treated, is the normalized tidal volume of the child to be treated, is the moisture interaction coefficient stored in the database, Normalized respiratory ratio of the children to be treated, is the respiratory ratio interaction coefficient stored in the database, Normalized gas exchange frequency values ​​for children to be treated, is the exchange interaction coefficient stored in the database, is the normalized airway resistance value of the child to be treated, is the airway resistance interaction coefficient stored in the database, is the respiratory status index of the child to be treated, are the initial coefficients stored in the database, is the interaction coefficient stored in the database, , is a natural constant and in this embodiment takes a value of 2.71.

[0053] It needs to be explained that , , , It can be obtained through the following steps: read the tidal volume reference value, respiratory ratio reference value, gas exchange frequency reference value, and respiratory airway resistance reference value of the child to be treated, and perform normalization processing, perform sum analysis based on the normalization processing results to obtain the respiratory sum value, perform ratio analysis on the normalization processing results and the respiratory sum value, and use the ratio analysis results as the corresponding coefficients.

[0054] , , , It can be obtained through the following steps: using historical monitoring data, evaluating the degree of interaction of various variables (such as tidal volume, respiratory ratio, gas exchange frequency, respiratory airway resistance, etc.) on the respiratory state index through statistical modeling and regression analysis, so as to fit the initial weight value, and then adjusting the value range of these coefficients based on sensitivity analysis to ensure that the formula has good adaptability to changes in the respiratory state index of different children to be treated, and then using scenario simulation technology (such as prediction models under different environments) to further optimize the applicability of the coefficient, and reasonably modify the weight coefficient according to the specific children and environmental characteristics.

[0055] , It can be obtained through the following steps: read the initial respiratory state index and respiratory interaction factor of the child to be treated (it should be noted that the initial respiratory state index and respiratory interaction factor are dimensionless values, so they can be directly calculated), perform sum analysis to obtain the respiratory sum value, and perform proportion analysis on the initial respiratory state index and respiratory interaction factor of the child to be treated and the respiratory sum value, and use the proportion analysis results as the corresponding coefficients.

[0056] In this implementation scheme, the respiratory state index of the child to be treated is calculated to quantitatively evaluate its respiratory function status, thereby providing accurate data support, which is helpful to formulate targeted treatment plans. Secondly, through comprehensive analysis of multiple respiratory parameters such as tidal volume, respiratory ratio, gas exchange frequency, respiratory airway resistance, etc., the respiratory function of the child to be treated is fully understood, and effective intervention measures are taken. At the same time, through normalization and comprehensive analysis, the influence of different units and dimensions is eliminated, ensuring that various indicators are compared and analyzed on the same scale, so that the calculated respiratory state index has stronger accuracy and comparability, thereby enhancing the accuracy of the treatment plan and avoiding treatment errors caused by data differences. Finally, through statistical regression analysis and sensitivity analysis, the influence of each respiratory parameter on the final result can be evaluated, and the coefficient can be optimized to ensure that the model has strong adaptability and good robustness, thereby improving the stability of treatment.

[0057] Specifically, the specific steps for taking corresponding preliminary aerosol treatment measures based on the comprehensive aerosol treatment index of the child to be treated are as follows: the comprehensive aerosol treatment index of the child to be treated is judged and analyzed with the preset comprehensive aerosol treatment index threshold; if the comprehensive aerosol treatment index of the child to be treated is lower than or equal to the preset comprehensive aerosol treatment index threshold, the first preliminary aerosol treatment measure is taken (i.e., low-intensity aerosol treatment is taken, with a small aerosol dose and a short aerosol time to reduce the side effects of drug use; aerosol drugs, using some milder drugs, such as salbutamol or drugs containing ambroxol and other detoxifying agents); sputum-clearing drugs to help relieve mild respiratory symptoms; low-frequency nebulization equipment, choose a milder nebulization equipment, such as a low-frequency nebulizer); if the comprehensive nebulization therapeutic index of the child to be treated is higher than the preset comprehensive nebulization therapeutic index threshold, take the second preliminary nebulization treatment measure (i.e. high-intensity nebulization, consider high-intensity nebulization treatment, such as increasing the nebulization dose and treatment time; strong drugs, such as formoterol, loratadine or hormone drugs to relieve severe respiratory inflammatory reactions; high-frequency nebulization equipment, use high-frequency nebulization equipment to help more effectively deliver drugs deep into the airways and improve lung ventilation).

[0058] In this implementation scheme, through the comprehensive nebulization treatment index, the intensity of treatment can be quantitatively adjusted according to the specific condition of the child, thereby effectively avoiding side effects caused by overtreatment, thereby ensuring the accuracy of treatment. The comprehensive nebulization treatment index can reflect the overall condition of the child to be treated and formulate a personalized initial plan to avoid fixed treatment plans that lead to poor results or delays in the disease. Secondly, when the treatment index is low, the use of low-frequency nebulization equipment and low-dose drugs can effectively save resources and avoid unnecessary waste of drugs and high-efficiency equipment. When the condition is more serious, high-frequency nebulization equipment and more potent drugs are selected to ensure the rational allocation of treatment resources and avoid overtreatment. Finally, by comparing and analyzing the treatment index with the threshold, more scientific and accurate treatment decisions can be made, thereby effectively improving the treatment effect of the children to be treated.

[0059] Specifically, when nebulization is performed on the child to be treated, the nebulization treatment data is obtained in real time, and monitoring and analysis are performed. The specific steps for optimizing and adjusting the initial nebulization treatment measures based on the monitoring and analysis results are as follows: obtain the reference value of nebulized drug deposition rate, airway mucus level, ventilation ratio, nebulized particle diameter, and nebulized drug concentration for the child to be treated under the initial nebulization treatment measures; conduct a comprehensive analysis of the reference value of nebulized drug deposition rate, airway mucus level, ventilation ratio, including nebulized drug deposition rate value, airway mucus level value, and ventilation ratio value for the child to be treated under the initial nebulization treatment measures to obtain the drug delivery index for the child to be treated under the initial nebulization treatment measures; obtain the reference value of nebulized particle diameter, nebulized drug concentration reference value for the child to be treated under the initial nebulization treatment measures The reference values, aerosol particle diameter values, aerosol drug concentration values ​​and drug concentration gradient index of the children to be treated under the preliminary aerosol treatment measures are standardized (i.e., the units are removed); and the reference values ​​of aerosol particle diameter, aerosol drug concentration, aerosol particle diameter values, aerosol drug concentration values ​​and drug concentration gradient index of the children to be treated under the standardized treatment are comprehensively analyzed to obtain the drug absorption index of the children to be treated under the preliminary aerosol treatment measures; the drug transport index and drug absorption index of the children to be treated under the preliminary aerosol treatment measures are comprehensively analyzed to obtain the therapeutic index of the children to be treated under the preliminary aerosol treatment measures; and the therapeutic index of the children to be treated under the preliminary aerosol treatment measures is compared and analyzed with the preset therapeutic index threshold value, and corresponding aerosol treatment optimization and adjustment measures are taken based on the comparison and analysis results.

[0060] Among them, the specific process of taking corresponding optimization and adjustment measures for atomization treatment based on the comparison and analysis results is as follows:

[0061] If the therapeutic index of the child to be treated under the initial nebulization treatment measure is lower than or equal to the preset therapeutic index threshold, the initial nebulization treatment measure is adjusted (if the initial nebulization treatment measure is the first initial nebulization treatment measure, the drug dose is increased, the dose of the nebulized drug is increased, or the drug combination is changed; the nebulization time is extended, the time of nebulization treatment is extended to ensure that the drug can be fully delivered to the respiratory tract of the child; the nebulization frequency is increased, and the nebulization frequency is increased to ensure that the lesion area can be continuously treated; use a stronger nebulization device, and select a device with a stronger nebulization effect to improve the drug delivery effect and help the drug reach the lungs of the child faster and better;

[0062] If the initial nebulization treatment measure is the second initial nebulization treatment measure, reduce the drug dosage. If the condition does not improve significantly, it may be caused by drug overdose or over-stimulation. Therefore, it is necessary to reduce the dosage of nebulized drugs to avoid unnecessary side effects; adjust the drug combination and consider using a milder drug combination to reduce the side effects of treatment; change the nebulization equipment and replace it with a more efficient equipment to improve the drug delivery efficiency and ensure that the drug can reach the child's lungs deeply);

[0063] If the therapeutic index of the child to be treated under the initial nebulization treatment measure is higher than the preset therapeutic index threshold, the initial nebulization treatment measure will not be adjusted, that is, the initial nebulization treatment measure will be maintained.

[0064] In addition, the reference values ​​of nebulized drug deposition rate, airway mucus level, ventilation ratio, nebulized particle diameter, and nebulized drug concentration for children under initial nebulized treatment measures can be obtained through biomedical literature databases (such as PubMed, UpToDate, and ClinicalKey).

[0065] The specific formulas for calculating the drug delivery index, drug absorption index, and therapeutic index of children to be treated under initial aerosol treatment measures are as follows: ;in, The drug delivery index for children to be treated under initial nebulized treatment measures, is the aerosol drug deposition rate value of the child to be treated under the initial aerosol treatment measures, It is the reference value of the aerosol drug deposition rate of the children to be treated under the initial aerosol treatment measures. is the drug deposition coefficient stored in the data, is the airway mucus level of the child to be treated under the initial nebulization treatment measures, The reference value of airway mucus level in children to be treated under initial nebulization treatment measures. is the airway mucus coefficient stored in the data, is the ventilation ratio of the child to be treated under the initial nebulization treatment measures, It is the reference value of ventilation ratio for children to be treated under the initial nebulization treatment measures. is the ventilation coefficient stored in the data, , is the drug absorption index of the children to be treated under the initial nebulization treatment measures, The diameter of the aerosol particles of the children to be treated after the standardized treatment under the initial aerosol treatment measures, It is the reference value of the aerosol particle diameter of the children to be treated under the initial aerosol treatment measures after standardized treatment. is the particle diameter coefficient stored in the data, It is the concentration value of the nebulized drug in the children to be treated under the initial nebulized treatment measures after standardized treatment. It is the reference value of the nebulized drug concentration for the children to be treated under the initial nebulized treatment measures after standardized treatment. is the atomization concentration coefficient stored in the data, It is the drug concentration gradient index of the children to be treated under the initial nebulization treatment measures after standardized treatment. is the gradient coefficient stored in the data, , The therapeutic index of the child to be treated under the initial nebulization treatment measures, is the transport coefficient stored in the data, is the treatment coefficient stored in the data, , is a natural constant and in this embodiment takes a value of 2.71.

[0066] It needs to be explained that , , It can be obtained through the following steps: read the reference value of the nebulized drug deposition rate, the reference value of the airway mucus level, and the reference value of the ventilation ratio of the child to be treated under the initial nebulized treatment measures, and perform standardization processing, perform sum analysis based on the results after standardization processing to obtain the delivery sum value, and perform proportion analysis on the results after standardization processing and the delivery sum value, and use the proportion analysis results as the corresponding coefficients.

[0067] , , It can be obtained through the following steps: read the aerosol particle diameter value, aerosol drug concentration value, and drug concentration gradient index of the children to be treated under the initial aerosol treatment measures after standardized treatment, and perform sum analysis to obtain the absorption sum value, and perform proportion analysis on the aerosol particle diameter value, aerosol drug concentration value, and drug concentration gradient index of the children to be treated under the initial aerosol treatment measures after standardized treatment and the absorption sum value, and use the proportion analysis results as the corresponding coefficients.

[0068] , It can be obtained through the following steps: read the drug delivery index and drug absorption index of the child to be treated under the initial nebulizer treatment measures (it should be noted that the drug delivery index and drug absorption index are dimensionless values, so they can be directly calculated), perform sum analysis to obtain the treatment sum value, and perform proportion analysis on the drug delivery index and drug absorption index of the treated child under the initial nebulizer treatment measures and the treatment sum value, and use the proportion analysis results as the corresponding coefficients.

[0069] The specific example of calculating the therapeutic index of a child to be treated under the initial aerosol treatment measure is as follows, and the following data are available:

[0070] The aerosol drug deposition rate value of the children to be treated under the initial aerosol treatment measures is: 0.15.

[0071] The airway mucus level of the children to be treated under initial nebulization treatment measures is (unit: mg / L): 60.00.

[0072] The ventilation ratio of the children to be treated under initial nebulization treatment measures is: 1.10.

[0073] The diameter value of aerosol particles under initial aerosol treatment measures for children to be treated is (unit: µm): 3.50.

[0074] The nebulized drug concentration value of the children to be treated under the initial nebulized treatment measures is (unit: mg / mL): 2.30.

[0075] The drug concentration gradient index of the children to be treated under the initial nebulization treatment measures is (unit: mg / mL): 0.52.

[0076] The reference value of aerosol drug deposition rate for children under initial aerosol treatment measures is: 0.20.

[0077] The reference value of airway mucus level for children to be treated under initial nebulization treatment measures is (unit: mg / L): 50.00.

[0078] The reference value of the ventilation ratio for children under initial nebulization treatment measures is: 1.00.

[0079] The reference value of aerosol particle diameter for children under initial aerosol treatment measures is (unit: µm): 3.00.

[0080] The reference value of nebulized drug concentration for children to be treated under initial nebulized treatment measures is (unit: mg / mL): 1.50.

[0081] The aerosol particle diameter value, aerosol drug concentration value, drug concentration gradient index, aerosol particle diameter reference value, and aerosol drug concentration reference value of the children to be treated under the initial aerosol treatment measures were standardized to obtain:

[0082] The diameter value of the aerosol particles in the children to be treated after standardized treatment under the initial aerosol treatment measures is: 0.45.

[0083] The nebulized drug concentration value of the children to be treated under the initial nebulized treatment measures after standardized treatment is: 0.38.

[0084] The drug concentration gradient index of the children to be treated under the initial nebulizer treatment measures after standardized treatment is: 0.54.

[0085] The reference value of aerosol particle diameter for children to be treated under initial aerosol treatment measures after standardized treatment is: 0.39.

[0086] The reference value of nebulized drug concentration for children to be treated under initial nebulized treatment measures after standardized treatment is: 0.31.

[0087] The drug deposition coefficient stored in the data is approximately: 0.42.

[0088] The airway mucus coefficient stored in the data is approximately: 0.34.

[0089] The ventilation coefficient stored in the data is approximately: 0.24.

[0090] The particle diameter coefficient stored in the data is approximately: 0.32.

[0091] The atomization concentration coefficient stored in the data is approximately: 0.28.

[0092] The gradient coefficient stored in the data is approximately: 0.40.

[0093] The transport coefficient stored in the data is approximately: 0.38.

[0094] The treatment coefficient stored in the data is approximately: 0.62.

[0095] Substitute the above data into the specific formulas of drug delivery index, drug absorption index and therapeutic index of the children to be treated under the initial aerosol treatment measures to calculate:

[0096] Drug delivery index for children to be treated under initial aerosol treatment measures = exp 0.42 *|1-（0.15 / 0.20）|+0.34*|1-（60.00 / 50.00）|+0.24*|1-（1.10 / 1.00）| ≈0.54.

[0097] The drug absorption index of the children to be treated under the initial nebulization treatment measures = 0.32*(0.45 / 0.39)+0.28*(0.38 / 0.31)+0.40*(1 / (0.54+1))≈0.97.

[0098] The therapeutic index of the child to be treated under the initial nebulization treatment measures = exp （（0.38*0.54+0.62*0.97） / （2.71-1）） ≈1.14.

[0099] In this embodiment, by real-time monitoring and analysis of the drug delivery and absorption of the children to be treated during nebulization treatment, the treatment effect is timely evaluated and adjusted, thereby ensuring that the treatment plan is always maintained at the optimal level, thereby avoiding possible inefficient or ineffective drug delivery during the treatment process. Secondly, by comprehensively analyzing multiple parameters such as drug deposition, airway mucus levels, ventilation ratio, etc. in the initial treatment of children, the specific treatment needs of the children can be accurately evaluated, thereby improving the treatment effect. By standardizing and comprehensively analyzing various indicators (such as aerosol particle diameter, drug concentration, etc.), the differences in units and dimensions can be eliminated, thereby providing a more accurate drug absorption index and therapeutic index. Accurate drug delivery and absorption help ensure the effectiveness of treatment, thereby reducing drug waste. Finally, by comparing the therapeutic index with the preset threshold, problems that arise during the treatment process can be discovered in a timely manner, thereby improving the safety and effectiveness of the treatment.

[0100] See also Figure 3 The embodiment of the present invention provides a technical solution: an intelligent nebulization system for pediatrics, comprising: a data acquisition module, a data analysis module, a comprehensive analysis module, a preliminary nebulization module, and a monitoring and optimization module; the data acquisition module is used to acquire physiological state data before the child to be treated undergoes nebulization therapy, and the physiological state data includes disease state data and respiratory state data; the data analysis module is used to perform data analysis on the physiological state data of the child to be treated, respectively, to obtain the disease state index and respiratory state index of the child to be treated; the comprehensive analysis module is used to perform comprehensive analysis on the disease state index and respiratory state index of the child to be treated, to obtain the comprehensive nebulization treatment index of the child to be treated; the preliminary nebulization module is used to take corresponding preliminary nebulization treatment measures based on the comprehensive nebulization treatment index of the child to be treated; the monitoring and optimization module is used to acquire nebulization treatment data in real time while treating the child to be treated, and to perform monitoring and analysis, and to optimize and adjust the preliminary nebulization treatment measures based on the monitoring and analysis results.

[0101] In summary, this application has at least the following effects:

[0102] Initial treatment measures are determined based on the child's comprehensive nebulizer treatment index to achieve a personalized treatment plan. Before treatment, detailed data analysis of the disease status and respiratory status is conducted to ensure that the treatment plan is designed for the child's specific condition. For different degrees of illness, the treatment plan meets the actual needs of the child, thereby effectively improving the treatment effect.

[0103] Through real-time feedback analysis of treatment data during nebulizer treatment, problems that arise during treatment can be discovered in a timely manner, and initial treatment measures can be adjusted based on the data to avoid overtreatment or insufficient treatment, thereby maximizing treatment safety. Children are more sensitive to treatment than adults, thereby effectively reducing risks during treatment.

[0104] By comparing and analyzing the therapeutic index with the preset therapeutic index threshold, the initial measures of nebulizer treatment are optimized and adjusted according to the results, thereby effectively avoiding overtreatment and reducing the side effects experienced by children, thereby ensuring the safety and comfort of children.

[0105] Through the efficient operation of the data acquisition module and the data analysis module, the physiological status data can be quickly and accurately converted into the index of the disease condition and respiratory status, and a comprehensive nebulization treatment index can be generated. Based on the comprehensive nebulization treatment index of the child, corresponding treatment measures can be taken, reducing the possibility of excessive or insufficient treatment, and shortening the treatment cycle while ensuring the efficacy. At the same time, the real-time monitoring and optimization functions of the monitoring optimization module can make optimizations at any time during the treatment process, so as to avoid duplication of treatment or waste of resources, thereby making the treatment process streamlined and efficient, thereby improving the hospital's treatment efficiency.

[0106] Although the preferred embodiments of the present invention have been described, those skilled in the art may make other changes and modifications to these embodiments once they have learned the basic creative concept. Therefore, the appended claims are intended to be interpreted as including the preferred embodiments and all changes and modifications that fall within the scope of the present invention.

[0107] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A pediatric intelligent atomization system, characterized in that: include: Data acquisition module, data analysis module, comprehensive analysis module, preliminary atomization module and monitoring optimization module; The data acquisition module is used to acquire physiological state data before the child to be treated undergoes aerosol treatment, wherein the physiological state data includes disease state data and respiratory state data; The data analysis module is used to analyze the physiological status data of the child to be treated, and obtain the disease status index and respiratory status index of the child to be treated; The comprehensive analysis module is used to conduct a comprehensive analysis of the disease state index and the respiratory state index of the child to be treated to obtain a comprehensive atomization treatment index of the child to be treated; The preliminary atomization module is used to take corresponding preliminary atomization treatment measures based on the comprehensive atomization treatment index of the child to be treated; The monitoring and optimization module is used to obtain aerosol treatment data in real time while treating the child to be treated, and to perform monitoring and analysis, and to optimize and adjust the preliminary aerosol treatment measures based on the monitoring and analysis results; Among them, the specific formula for calculating the comprehensive aerosol therapeutic index of children to be treated is as follows: ； in, is the comprehensive aerosol therapeutic index of the child to be treated. is the disease status index of the child to be treated, is the disease coefficient stored in the database, is the respiratory status index of the child to be treated, is the breathing coefficient stored in the database, is the interaction coefficient stored in the database.

2. The pediatric intelligent atomization system according to claim 1, characterized in that: The disease status data include blood oxygen saturation value, body temperature value, reactive protein level value, arterial blood gas index and oxygenation index; the respiratory status data include tidal volume value, respiratory ratio value, gas exchange frequency value and respiratory airway resistance value; the nebulization treatment data include nebulized drug deposition rate value, airway mucus level value, ventilation ratio value, nebulized particle diameter value, nebulized drug concentration value and drug concentration gradient index.

3. The pediatric intelligent atomization system according to claim 2, characterized in that: The specific steps for obtaining the disease state index of the child to be treated are as follows: Obtaining a reference value of oxygen partial pressure and a reference value of carbon dioxide partial pressure of the child to be treated, and performing standardization processing, and performing weighted processing based on the standardized reference value of oxygen partial pressure and the reference value of carbon dioxide partial pressure of the child to be treated to obtain a reference index of arterial blood gas analysis of the child to be treated; The blood oxygen saturation reference value and body temperature reference value of the child to be treated are obtained, and the blood oxygen saturation value, body temperature value, and arterial blood gas index are combined for comprehensive analysis to obtain the infection index of the child to be treated; Standardize the infection index, reactive protein level, and oxygenation index of the children to be treated; The infection index, reactive protein level and oxygenation index of the children to be treated after standardized treatment are comprehensively analyzed to obtain the disease status index of the children to be treated.

4. The pediatric intelligent atomization system according to claim 3, characterized in that: The specific formula for calculating the infection index and disease status index of children to be treated is as follows: ； in, is the infection index of the child to be treated, is the blood oxygen saturation value of the child to be treated, is the reference value of blood oxygen saturation for children to be treated, is the blood oxygen coefficient stored in the database, is the temperature of the child to be treated, is the reference value of the temperature of the child to be treated, is the temperature coefficient stored in the database, is the arterial blood gas index of the child to be treated, is the arterial blood gas reference index for children to be treated, is the blood gas coefficient stored in the database, is the disease status index of the child to be treated, is the infection index of the children to be treated after standardized treatment. is the infection coefficient stored in the database, is the level of protein in the children to be treated after standardized treatment. is the protein coefficient stored in the database, is the oxygenation index of the child to be treated after standardized treatment. is the oxygenation coefficient stored in the database, , is a natural constant.

5. The pediatric intelligent atomization system according to claim 2, characterized in that: The specific steps to obtain the respiratory status index of the child to be treated are as follows: Obtaining the reference value of tidal volume, respiratory ratio, gas exchange frequency, and respiratory airway resistance of the child to be treated, and performing a comprehensive analysis based on the tidal volume value, respiratory ratio, gas exchange frequency value, and respiratory airway resistance value to obtain the initial respiratory state index of the child to be treated; Normalize the tidal volume, respiratory ratio, gas exchange frequency, and respiratory airway resistance values ​​of the children to be treated; The normalized tidal volume, respiratory ratio, gas exchange frequency, and respiratory airway resistance of the children to be treated were comprehensively analyzed to obtain the respiratory interaction factor of the children to be treated. The initial respiratory state index and respiratory interaction factor of the child to be treated are comprehensively analyzed to obtain the respiratory state index of the child to be treated.

6. The pediatric intelligent atomization system according to claim 5, characterized in that: The specific formulas for calculating the initial respiratory state index, respiratory interaction factor, and respiratory state index of the child to be treated are as follows: ； in, is the initial respiratory status index of the child to be treated, , , , They are the tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value of the child to be treated. , , , These are the tidal volume reference value, respiratory ratio reference value, gas exchange frequency reference value, and respiratory airway resistance reference value of the child to be treated. , , , They are the tidal coefficient, respiratory ratio coefficient, exchange coefficient, and airway resistance coefficient stored in the database. , is the respiratory interaction factor for the child to be treated, , , , They are the tidal volume value, respiratory ratio value, gas exchange frequency value, and respiratory airway resistance value of the child to be treated after normalization. , , , They are the tidal interaction coefficient, respiratory ratio interaction coefficient, exchange interaction coefficient, and airway resistance interaction coefficient stored in the database. is the respiratory status index of the child to be treated, , They are the initial coefficient and interaction coefficient stored in the database, , is a natural constant.

7. The pediatric intelligent atomization system according to claim 1, characterized in that: The specific steps for taking corresponding preliminary nebulizer treatment measures based on the comprehensive nebulizer treatment index of the child to be treated are as follows: The comprehensive aerosol treatment index of the child to be treated is judged and analyzed with the preset comprehensive aerosol treatment index threshold; If the comprehensive aerosol therapeutic index of the child to be treated is lower than or equal to the preset comprehensive aerosol therapeutic index threshold, the first preliminary aerosol treatment measure is taken; If the comprehensive nebulization treatment index of the child to be treated is higher than the preset comprehensive nebulization treatment index threshold, the second preliminary nebulization treatment measure is taken.

8. The pediatric intelligent atomization system according to claim 2, characterized in that: When atomizing a child, the specific steps for obtaining atomizing treatment data in real time, conducting monitoring and analysis, and optimizing and adjusting the initial atomizing treatment measures based on the monitoring and analysis results are as follows: Obtain reference values ​​for aerosolized drug deposition rate, airway mucus level, ventilation ratio, aerosolized particle diameter, and aerosolized drug concentration for children to be treated under initial aerosolized treatment measures; Comprehensively analyze the reference values ​​of aerosolized drug deposition rate, airway mucus level, ventilation ratio, aerosolized drug deposition rate, airway mucus level, and ventilation ratio of the children to be treated under the initial aerosolized treatment measures to obtain the drug delivery index of the children to be treated under the initial aerosolized treatment measures; Standardize the reference values ​​of aerosol particle diameter, aerosol drug concentration, aerosol particle diameter, aerosol drug concentration, and drug concentration gradient index for children under initial aerosol treatment measures; A comprehensive analysis was conducted on the reference values ​​of aerosol particle diameter, aerosol drug concentration, aerosol particle diameter, aerosol drug concentration, and drug concentration gradient index of the children to be treated under the initial aerosol treatment measures after standardized treatment to obtain the drug absorption index of the children to be treated under the initial aerosol treatment measures; Comprehensively analyzing the drug delivery index and drug absorption index of the children to be treated under the initial aerosol treatment measures, to obtain the therapeutic index of the children to be treated under the initial aerosol treatment measures; The therapeutic index of the children to be treated under the initial nebulizer treatment measures will be compared and analyzed with the preset therapeutic index threshold, and corresponding nebulizer treatment optimization and adjustment measures will be taken based on the comparison and analysis results.

9. The pediatric intelligent atomization system according to claim 8, characterized in that: The specific formulas for calculating the drug delivery index, drug absorption index, and therapeutic index of children to be treated under initial aerosol treatment measures are as follows: ; in, The drug delivery index for children to be treated under initial nebulized treatment measures, , , They are the aerosol drug deposition rate, airway mucus level, and ventilation ratio of the children to be treated under the initial aerosol treatment measures. , , These are the reference values ​​for the aerosolized drug deposition rate, airway mucus level, and ventilation ratio of the children to be treated under the initial aerosolized treatment measures. , , They are the drug deposition coefficient, airway mucus coefficient, and ventilation coefficient stored in the data, respectively. , is the drug absorption index of the children to be treated under the initial nebulization treatment measures, , , They are the aerosol particle diameter value, aerosol drug concentration value, and drug concentration gradient index of the children to be treated under the initial aerosol treatment measures after standardized treatment. , These are the reference values ​​of aerosol particle diameter and aerosol drug concentration for children to be treated under the initial aerosol treatment measures after standardized treatment. , , They are the particle diameter coefficient, atomization concentration coefficient, and gradient coefficient stored in the data, respectively. , The therapeutic index of the child to be treated under the initial nebulization treatment measures, , They are the transport coefficient and treatment coefficient stored in the data, , is a natural constant.

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