Cryopreservation device

Abstract

The embodiment of the invention relates to the technical field of low-temperature storage equipment, in particular to a cryopreservation device. According to the cryopreservation device provided by the embodiment of the invention, the first pick-and-place opening is formed, so that the sample box can enter and exit from the buffer cavity through the first pick-and-place opening; the first taking and placing opening is opened and closed by arranging the first heat preservation door. By arranging the sample taking and placing mechanism, the sample box is input into or output from the cache cavity through the first taking and placing opening. The sample taking and placing mechanism is provided with a bearing part for accommodating a sample box; the sealing component is arranged and used for sealing the first taking and placing opening; the driving part is configured to drive the bearing part and the sealing part to move towards the first heat preservation door at the same time, and when the sealing part seals the first taking and placing opening, the bearing part is driven to move relative to the sealing part and enter and exit the buffering cavity through the first taking and placing opening. The cold air in the buffer cavity cannot be greatly leaked through the first taking and placing opening, so that the stability of the temperature in the buffer cavity is ensured, the temperature fluctuation in the buffer cavity is reduced, and the storage quality of the sample is ensured.

Description

Technical Field

[0001] The embodiments of the present application relate to the technical field of low-temperature storage equipment, and in particular to a freezing device. Background Art

[0002] In order to keep biological tissues such as stem cells, blood, and immune cells active for a long time, samples are usually stored in sample tubes, and then a sample box containing multiple sample tubes is stored in a freezing device.

[0003] The storage temperature in the cryopreservation device is usually relatively low, such as -80°C. Even in the buffer area of ​​the cryopreservation device, the temperature is below zero. For traditional cryopreservation devices, when storing or taking out biological samples, the door needs to be opened to put the biological samples in or out. During this process, the temperature in the cryopreservation device is prone to fluctuations, affecting the stability and safety of the biological samples. In addition, moisture in the outside air is prone to condensation at the door, affecting the closure of the door. Summary of the invention

[0004] The embodiment of the present application provides a cryopreservation device to solve the technical problem of temperature fluctuation caused by opening the door when storing and taking out biological samples.

[0005] In a first aspect, an embodiment of the present application provides a freezing device, comprising:

[0006] Box assembly, structure formed:

[0007] a buffer chamber configured to store a sample cartridge;

[0008] A first access opening is configured to connect the cache cavity with the outside atmosphere;

[0009] a first heat-insulating door configured to open and close the first access opening;

[0010] A sampling mechanism is configured to input or output the sample box into or out of the cache cavity through the first access port; the sampling mechanism comprises:

[0011] A carrying component configured to accommodate the sample box;

[0012] A sealing component, sleeved on the outer side of the bearing component;

[0013] A driving component connected to the bearing component;

[0014] Wherein, when the sample box is input into the cache cavity, the driving component is configured to drive the supporting component and the sealing component to move toward the first thermal insulation door at the same time, and when the sealing component seals the first access port, drive the supporting component to move so that part of the supporting component drives the sample box to enter the cache cavity through the first access port.

[0015] The freezing device provided in the embodiment of the present application stores samples by setting a cache cavity. By setting a first access port, the sample box can enter and exit the cache cavity through the first access port; the first access port is opened and closed by setting a first heat preservation door. A sampling mechanism is also set to input or output the sample box from the cache cavity through the first access port. Among them, the sampling mechanism is configured to accommodate the sample box by setting a bearing component; a sealing component is provided to seal the first access port; the driving component is configured to drive the bearing component and the sealing component to move toward the first heat preservation door at the same time, and when the sealing component seals the first access port, the bearing component is driven to move relative to the sealing component to enter and exit the cache cavity through the first access port.

[0016] Therefore, when the sample box is input into the cache cavity, the first access port is first sealed by the sealing component, and then the first thermal insulation door is driven to open the first access port, so that part of the bearing component and the sample box enter the cache cavity through the first access port. The cold air in the cache cavity cannot leak out in large quantities through the first access port, which is conducive to ensuring the stability of the temperature in the cache cavity, reducing the temperature fluctuation in the cache cavity, and ensuring the storage quality of the sample. Moreover, there is no large amount of outside air entering the cache cavity, which is conducive to reducing condensation or even ice at the edge of the first access port, which can ensure the reliability of the first thermal insulation door closing the first access port, and ensure the smoothness of the first thermal insulation door opening and closing the first access port.

[0017] In some embodiments of the present application, the box assembly includes a box plate, and the box plate is provided with the first access opening;

[0018] The first heat-insulating door is located in the buffer cavity and covers the top surface of the box board;

[0019] The sampling mechanism is located below the box plate; the driving component drives the bearing component to push the first thermal insulation door to move, so that the first thermal insulation door opens the first sampling port.

[0020] In some embodiments of the present application, the box body assembly is provided with a box plate, and a first access opening is provided on the box plate, and the first thermal insulation door contacts the box plate to close the first access opening. The first thermal insulation door cover is provided on the top surface of the box plate. In this arrangement, the weight of the first thermal insulation door can be used to press the box plate to seal the first access opening; and the downward gravity of the first thermal insulation door can also be used to make the first thermal insulation door close the first access opening. Moreover, the taking and placing mechanism is provided below the box plate, and the first thermal insulation door is pushed open by the taking and placing mechanism. The first thermal insulation door does not need to be provided with an additional driving mechanism, which is conducive to simplifying the structure of the first thermal insulation door.

[0021] In some embodiments of the present application, the bearing component includes:

[0022] A carrying platform, configured to form a receiving cavity for receiving the sample box;

[0023] A connecting member connected to a side of the supporting platform away from the accommodating cavity; an end of the connecting member away from the supporting platform is connected to the driving component;

[0024] The sealing component is sleeved on the outer side of the connecting member.

[0025] In some embodiments of the present application, the carrying component is provided with a carrying platform to accommodate the sample box; the carrying platform and the driving component are respectively connected by a connecting member, and the sealing component is sleeved on the outer side of the connecting member. In this way, the driving component drives the connecting component to move through the connecting member, and drives the sealing component to move; the driving component is away from the carrying platform, and thus away from the sample box, which can reduce the vibration generated by the operation of the driving component and affect the stability of the sample box transportation.

[0026] In some embodiments of the present application, the connecting member includes:

[0027] A hollow shaft, the hollow shaft being connected to the bearing platform and the driving component respectively;

[0028] A heating element is arranged inside the hollow shaft; the heating element is configured to heat the hollow shaft.

[0029] The connecting components of some embodiments of the present application connect the support platform and the driving component by setting a hollow shaft, and a heating element is set inside the hollow shaft to heat the hollow shaft, increase the temperature of the hollow shaft, reduce the possibility of condensation and formation of water droplets on the outer surface of the hollow shaft, which is beneficial to improve the dryness of the hollow shaft and facilitate the continuous entry and exit of the portion of the hollow shaft in the cache cavity without easy freezing.

[0030] In some embodiments of the present application, the end portion of the hollow shaft away from the supporting platform is structured to form a first arc-shaped surface;

[0031] The sampling mechanism further includes a connecting structure, which includes:

[0032] a first connecting seat, configured to form a second arcuate surface that matches the first arcuate surface, so that the end of the hollow shaft can rotate relative to the first connecting seat;

[0033] A second connecting seat is connected to the output end of the driving component; the second connecting seat is structured to form a connecting groove to accommodate the first connecting seat; the second connecting seat is structured to limit the position of the first connecting seat along a first direction, and has a gap between the second connecting seat and the first connecting seat in a first plane; wherein the first direction is parallel to the axial direction of the hollow shaft, and the first plane is perpendicular to the axial direction of the hollow shaft.

[0034] In some embodiments of the present application, a first curved surface is constructed at the end of the hollow shaft and aligned with the second curved surface of the first connecting seat, so that the end of the hollow shaft can rotate relative to the first connecting seat; a gap is set between the second connecting seat and the first connecting seat, so that the first connecting seat can move within the first plane within the second connecting seat, thereby offsetting processing errors, installation errors, and stresses and strains caused by over-constraints, thereby extending the service life of the hollow shaft.

[0035] In some embodiments of the present application, a sealing structure is provided between the sealing component and the connecting member.

[0036] Some embodiments of the present application provide a sealing structure between the sealing component and the connecting member to achieve a seal between the sealing component and the connecting member, thereby improving the reliability of the sealing component on the first loading and unloading port and reducing the possibility of cold air in the cache cavity leaking out through the sealing component and the connecting member.

[0037] In some embodiments of the present application, the sealing component includes:

[0038] A main body, sleeved on the outer side of the connecting member;

[0039] A sealing portion is disposed on the main body; the sealing portion is configured to seal the first loading and unloading opening.

[0040] In some embodiments of the present application, the sealing component is provided with a main body portion sleeved on the outer side of the connecting member, and the sealing portion is provided to seal the first access opening, so as to improve the reliability of the sealing component sealing the first access opening.

[0041] In some embodiments of the present application, a first guide structure is provided between the sealing component and the bearing component, so that the bearing component moves toward the first thermal insulation door along the first guide structure.

[0042] In some embodiments of the present application, a first guiding structure is arranged between the sealing component and the carrying component to guide the movement of the carrying component, thereby improving the linear movement accuracy of the carrying component, reducing the situation where the inclination of the carrying component affects the stability of sample box transportation, and reducing the situation where the inclination of the carrying component causes increased friction between the carrying component and the sealing component.

[0043] In some embodiments of the present application, the driving component includes:

[0044] A first driving mechanism connected to the bearing component; the first driving mechanism is configured to drive the bearing component to move relative to the sealing component;

[0045] The second driving mechanism is connected to the first driving mechanism; the second driving mechanism is configured to drive the first driving mechanism to move, so as to drive the sealing component and the bearing component to move toward the first thermal insulation door, so that the sealing component moves to seal the first loading and unloading port.

[0046] In some embodiments of the present application, the driving component is independently controlled by setting up two driving mechanisms, the first driving mechanism is configured to independently drive the bearing component to move relative to the sealing component, and the second driving mechanism is configured to drive the first driving mechanism to move toward the first thermal insulation door, thereby driving the bearing component and the sealing component to move toward the first thermal insulation door together, so that the movement of the sealing component and the independent movement of the bearing component can be controlled more precisely.

[0047] In some embodiments of the present application, the driving component includes:

[0048] An elastic member, sleeved on the outer side of the bearing member and located between the sealing member and the connecting end of the bearing member;

[0049] The third driving mechanism is connected to the connecting end of the supporting component, and is configured to drive the sealing component and the supporting component to move toward the first thermal insulation door through the elastic member; and when the sealing component seals the first access port, the third driving mechanism drives the supporting component to move, so that part of the supporting component drives the sample box to enter and exit the cache cavity through the first access port.

[0050] In some embodiments of the present application, the driving component can drive the sealing component and the bearing component to move vertically simultaneously by setting a driver and cooperating with an elastic member, and can also drive the bearing component alone to move vertically relative to the sealing component, which is beneficial to simplify the structure of the driving component and reduce the cost of the driving component.

[0051] In a second aspect, an embodiment of the present application provides a freezing device, comprising:

[0052] a buffer chamber configured to store a sample cartridge;

[0053] A first access opening is configured to connect the cache cavity with the outside atmosphere;

[0054] A first heat-insulating door, configured to open and close the first access opening; the first heat-insulating door is located in the cache cavity;

[0055] The sampling mechanism is configured to input or output the sample box into or out of the cache cavity through the first access port; and is configured to first seal the first access port, and then drive the first thermal insulation door to open the first access port to input or output the sample box into or out of the cache cavity.

[0056] The freezing device provided in the embodiment of the present application stores samples by setting a cache cavity. By setting a first access port, the sample box can enter and exit the cache cavity through the first access port; the first access port is opened and closed by setting a first thermal insulation door. The sample box is also input or output from the cache cavity through the first access port by setting a sampling mechanism. Among them, the sampling mechanism is configured to first seal the first access port, and then drive the first thermal insulation door to open the first access port. As a result, the cold air in the cache cavity cannot leak out in large quantities through the first access port, which is conducive to ensuring the stability of the temperature in the cache cavity, reducing the temperature fluctuation in the cache cavity, and ensuring the storage quality of the sample. Moreover, there is no large amount of outside air entering the cache cavity, which is conducive to reducing condensation or even ice on the edge of the first access port, which can ensure the reliability of the first thermal insulation door closing the first access port, and ensure the smoothness of the first thermal insulation door opening and closing the first access port.

[0057] In a third aspect, an embodiment of the present application provides a freezing device, comprising:

[0058] Box assembly, structure formed:

[0059] a buffer chamber configured to store a sample cartridge;

[0060] A first access opening is configured to connect the cache cavity with the outside atmosphere;

[0061] a first heat-insulating door configured to open and close the first access opening;

[0062] A sampling mechanism is configured to input or output the sample box into or out of the cache cavity through the first access port; the sampling mechanism comprises:

[0063] A carrying component configured to accommodate the sample box;

[0064] A sealing component, sleeved on the outer side of the bearing component;

[0065] A driving component connected to the bearing component;

[0066] Wherein, when the sample box in the cache cavity is output,

[0067] The driving component is first configured to drive the bearing component and the sealing component to move toward the first heat preservation door at the same time; and when the sealing component seals the first access opening, the bearing component is driven to move so that part of the bearing component enters the cache cavity through the first access opening and receives the sample box;

[0068] The driving component is further configured to drive the carrying component to move so that part of the carrying component and the sample box thereon are moved out of the cache cavity through the first access port; and when the first thermal insulation door closes the first access port, the carrying component and the sealing component are driven to move away from the first thermal insulation door at the same time.

[0069] The freezing device provided in some embodiments of the present application stores samples by setting a cache cavity. A first access port is set so that the sample box can enter and exit the cache cavity through the first access port; the first access port is opened and closed by setting a first heat preservation door. A sample taking and placing mechanism is also set to input or output the sample box from the cache cavity through the first access port. The sample taking and placing mechanism is provided by setting a bearing component to accommodate the sample box; and a sealing component is provided to seal the first access port.

[0070] In the process of outputting the sample box from the cache cavity, when part of the bearing component enters the cache cavity, the sealing component is first used to seal the first access port, and then the first thermal insulation door opens the first access port; when the bearing component drives the sample box out of the cache cavity, the first thermal insulation door is first used to close the first access port, and then the sealing component is driven to open the first access port. With such an arrangement, the cold air in the cache cavity cannot leak out in large quantities through the first access port, which is beneficial to ensuring the temperature stability in the cache cavity, reducing the temperature fluctuation in the cache cavity, and ensuring the storage quality of the sample. Moreover, there is no large amount of outside air entering the cache cavity, which is beneficial to reducing condensation or even ice at the edge of the first access port, which can ensure the reliability of the first thermal insulation door closing the first access port, and ensure the smoothness of the first thermal insulation door opening and closing the first access port. BRIEF DESCRIPTION OF THE DRAWINGS

[0071] In order to more clearly illustrate the implementation methods in the embodiments of the present application or the related technologies, the following is a brief introduction to the drawings required for use in the embodiments or the related technology descriptions. Obviously, the drawings described below are some embodiments of the present application, and a person skilled in the art can also obtain other drawings based on these drawings.

[0072] Figure 1 A schematic diagram of the structure of a freezing device provided in some embodiments of the present application;

[0073] Figure 2 A schematic diagram of the internal structure of a freezing device provided in some embodiments of the present application;

[0074] Figure 3 A schematic diagram of the internal structure of a freezing device provided in some embodiments of the present application;

[0075] Figure 4 A schematic diagram of a portion of the structure in the cache cavity when the first thermal insulation door is opened provided in some embodiments of the present application;

[0076] Figure 5 A schematic diagram of a portion of the structure in the cache cavity when the first thermal insulation door is closed provided in some embodiments of the present application;

[0077] Figure 6 A cross-sectional view of a sealing component and a bearing component provided in some embodiments of the present application;

[0078] Figure 7 A schematic diagram of the cooperation between the sealing component and the carrier platform provided in some embodiments of the present application;

[0079] Figure 8 A schematic diagram of a first access opening closed in some embodiments of the present application;

[0080] Fig. 9 A schematic diagram of a sealing component of a sampling mechanism provided in some embodiments of the present application sealing a first sampling port;

[0081] Fig.10 A schematic diagram of a first access opening provided in some embodiments of the present application when it is opened;

[0082] Fig.11 for Figure 6 Enlarged schematic diagram of the middle P region;

[0083] Fig.12 for Figure 6 Enlarged schematic diagram of the middle Q region;

[0084] Fig.13 A schematic diagram of the structure of a sampling mechanism and a first sampling port provided in some embodiments of the present application;

[0085] Fig.14 A cross-sectional view of a sampling mechanism provided in some other embodiments of the present application;

[0086] Fig.15 A schematic diagram of a first access opening closed provided in some other embodiments of the present application;

[0087] Fig.16 A schematic diagram of a sealing component of a sampling mechanism provided in some other embodiments of the present application sealing a first sampling port;

[0088] Fig.17 Schematic diagram of the first access opening when open provided in some other embodiments of the present application.

[0089] Description of reference numerals:

[0090] 10: sample box;

[0091] 20: storage mechanism; 21: annular cage; 22: transfer manipulator;

[0092] 30: Taking and placing mechanism;

[0093] 40: tube picking mechanism; 50: scanning mechanism;

[0094] 60: Transfer station;

[0095] 100: box assembly; 101: storage cavity; 102: cache cavity; 103: first access opening; 104: second access opening; 110: first box; 111: first box liner; 120: second box; 121: second box liner; 122: display device; 130: first heat preservation door; 131: second slider; 132: top member; 140: second heat preservation door; 150: box board; 151: second guide rail; 160: mounting plate; 161: second sleeve;

[0096] 200: bearing component; 210: bearing platform; 211: accommodating cavity; 220: connecting member; 221: hollow shaft; 2211: inner ring of bearing; 222: heating element; 223: connecting rod;

[0097] 300: sealing component; 310: main body; 311: base; 312: heat insulation; 320: sealing; 330: receiving groove; 340: sealing structure; 341: sealing ring; 351: first end cover; 352: second end cover; 360: first sleeve;

[0098] 400: driving component; 410: first driving mechanism; 420: second driving mechanism; 430: elastic member; 440: third driving mechanism;

[0099] 500: connection structure; 510: first connection seat; 520: second connection seat; 521: connection groove; 522: seat body; 523: third end cover; 524: fourth end cover;

[0100] 600: First guide structure. DETAILED DESCRIPTION

[0101] In order to make the purpose, implementation mode and advantages of the present application clearer, the exemplary implementation mode of the present application will be clearly and completely described below in conjunction with the drawings in the exemplary embodiments of the present application. Obviously, the described exemplary embodiments are only part of the embodiments of the present application, rather than all the embodiments.

[0102] It should be noted that the brief description of terms in this application is only for the convenience of understanding the embodiments described below, and is not intended to limit the embodiments of this application. Unless otherwise specified, these terms should be understood according to their common and usual meanings.

[0103] In addition, the terms "include" and "have" and any variations thereof are intended to cover but not exclude inclusion, for example, a product or device comprising a list of components is not necessarily limited to those components expressly listed but may include other components not expressly listed or inherent to such products or devices.

[0104] In the description of the present application, it should be understood that the terms "center", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0105] The terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, unless otherwise specified, "plurality" means two or more.

[0106] In the description of this application, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0107] The storage temperature in a cryogenic device is usually relatively low, such as -80°C. Even in the buffer area of ​​a cryogenic device, the temperature is below zero, such as -40°C.

[0108] For traditional cryopreservation devices, when storing or taking out biological samples, the door needs to be opened to put the biological samples in or out. During this process, the temperature inside the cryopreservation device is prone to fluctuations, affecting the stability and safety of the biological samples. Moreover, the temperature fluctuations caused by each opening and closing of the door require additional cooling by the refrigeration system, which increases energy consumption. The moisture in the outside air is easy to condense at the door, or even freeze, affecting the closing and sealing of the door.

[0109] In view of this, the cryopreservation device of the embodiment of the present application is provided with a sampling mechanism to transport or output the sample box into the cache chamber. When inputting and outputting the sample box, the sampling mechanism first seals the access port, and then opens the door at the access port to prevent the cache chamber from being directly connected to the outside atmosphere, thereby reducing the impact of sample input and output on the temperature in the cache chamber, improving the storage quality of the cryopreservation device, and reducing energy consumption; reducing the possibility of condensation at the access port to form water droplets, and ensuring the normal opening and closing of the door.

[0110] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0111] Combination Figure 1 and Figure 2 Some embodiments of the present application provide a cryopreservation device, which is used to freeze and preserve biological samples.

[0112] The freezing device may include a box assembly 100, which serves as an appearance component of the freezing device and not only forms a storage chamber for storing biological samples, but also forms an installation chamber for a freezing device driving component 400 and the like, and an operation chamber for biological samples.

[0113] In some embodiments, the box assembly 100 is constructed to form a storage cavity 101, and the storage cavity 101 is configured to store the sample box 10. The sample box 10 is a container for storing biological samples, and the drawings of the embodiments of the present application are schematically shown in a rectangular box shape, but this does not limit the shape and structure of the sample box 10.

[0114] Reference Figure 2 and Figure 3 The freezing device may include a storage mechanism 20 , which is installed in the storage cavity 101 and is used to place the sample box 10 .

[0115] The freezing device may include a transfer robot 22 installed in the storage cavity 101 to place the sample box 10 on the storage mechanism 20 , or transfer the sample box 10 of the storage mechanism 20 to outside the storage cavity 101 .

[0116] In some embodiments, the storage mechanism 20 may include an annular cage 21 , and the transfer robot 22 may be located at the center of the annular cage 21 , so as to improve the structural compactness of the freezing device and improve the storage utilization rate in the storage chamber 101 .

[0117] The annular cage 21 may include a plurality of storage racks, which are arranged at intervals along the circumference to provide more storage locations.

[0118] The annular rotating cage 21 can be configured to rotate around its axis; the transfer robot 22 is configured to move vertically and along the sampling direction (corresponding to the Figure 2 The two cooperate to transfer the sample box 10 at any position of the annular rotating cage 21.

[0119] In some embodiments, a plurality of annular rotating cages 21 may be provided, the plurality of annular rotating cages 21 are coaxially arranged, and the plurality of annular rotating cages 21 are sequentially sleeved in the radial direction. In this way, not only the storage capacity of the sample box 10 in the storage cavity 101 can be increased, but also the structure of the storage mechanism 20 is compact, which is conducive to improving the space utilization rate in the storage cavity 101.

[0120] exist Figure 2 and Figure 3 In the structure shown, two annular cages 21 are provided. This is only a schematic representation of the number of annular cages 21, and does not limit the number of annular cages 21. Figure 2 and Figure 3 In the figure, only one storage rack is shown in the annular cage 21, which is for schematic illustration and does not limit the number of storage racks.

[0121] Usually, the temperature in the storage chamber 101 is relatively low, for example, minus 80° C. If the sample box 10 is directly transferred between the storage chamber 101 and the external environment, the sample box 10 is prone to frost, and the temperature difference is large, which is not conducive to the storage quality of the sample and also causes the temperature fluctuation of the storage chamber 101 .

[0122] To this end, in some embodiments, the box assembly 100 is further configured to form a cache chamber 102, which is configured to store the sample box 10. It is understandable that the sample box 10 is stored in the cache chamber 102 for a short time, and mainly performs operations such as scanning and picking the samples in the sample box 10.

[0123] The storage temperature of the cache cavity 102 is higher than the temperature of the storage cavity 101. Of course, the storage temperature of the cache cavity 102 is lower than zero degrees Celsius. Exemplarily, the storage temperature of the cache cavity 102 is minus 30 degrees Celsius, minus 40 degrees Celsius, and the like.

[0124] In some embodiments, the freezing device includes two refrigeration systems, one of which is used to cool the storage cavity 101 and the other is used to cool the cache cavity 102. This arrangement is conducive to accurately controlling the temperatures of the storage cavity 101 and the cache cavity 102.

[0125] The cache chamber 102 is located on the side of the storage chamber 101, so that it is convenient to take and put samples. Figure 2 At this time, the transfer robot 22 is extended and retracted along the sampling direction to realize the transfer of the sample box 10 between the buffer chamber 102 and the storage chamber 101.

[0126] The buffer chamber 102 is configured to be selectively connected to the storage chamber 101, so that the sample box 10 can be transferred between the buffer chamber 102 and the storage chamber 101. In this way, the sample can be operated in the low temperature environment of the buffer chamber 102, avoiding frost on the sample box 10 and affecting the sample operation. Moreover, the sample box 10 enters and exits the storage chamber 101 through the buffer chamber 102, which can reduce the impact of sudden temperature changes on the sample storage quality and the impact on the temperature in the storage chamber 101.

[0127] In some embodiments, in combination Figure 3 and Figure 4 The box assembly 100 is also configured to form a first access opening 103 , which is configured to connect the cache chamber 102 with the outside atmosphere, so that the sample box 10 can enter and exit the cache chamber 102 through the first access opening 103 .

[0128] Exemplarily, the first access opening 103 is located on a side of the cache cavity 102 away from the storage cavity 101 , so that there is sufficient space to access and place the sample box 10 through the first access opening 103 .

[0129] Combination Figure 2 and Figure 3 The freezing device may include a first heat preservation door 130, which is configured to open or close the first access port 103. The first heat preservation door 130 may be opened by an operator; the first heat preservation door 130 may also be an electric door, which is opened or closed under the control of a control device of the freezing device.

[0130] Among them, Figure 2 In the embodiment, the first heat preservation door 130 closes the first access opening 103; Figure 3 In the process, the first heat preservation door 130 is driven to open the first loading and unloading opening 103 .

[0131] In some embodiments, the cryopreservation device may include a sample taking and placing mechanism 30, which is configured to input or output the sample box 10 into or out of the cache chamber 102 through the first access port 103. The sample taking and placing mechanism 30 is located outside the cache chamber 102, so as to facilitate inputting the sample box 10 into the cache chamber 102 through the first access port 103, or outputting the sample box 10 in the cache chamber 102.

[0132] In some embodiments, in combination Figure 4The box assembly 100 is also configured to form a second access port 104 , which connects the cache chamber 102 and the storage chamber 101 . The sample box 10 is transferred between the storage chamber 101 and the cache chamber 102 through the second access port 104 .

[0133] Combination Figure 2 The freezing device may include a second heat preservation door 140, and the second heat preservation door 140 is configured to open or close the second access port 104. The second heat preservation door 140 is an electric door, which can be opened or closed under the control of the control device.

[0134] Continue to refer to Figure 1 In some embodiments, the box assembly 100 includes a first box 110 , and the first box 110 is configured to form a storage cavity 101 .

[0135] The first box body 110 may include a first box shell, and the first box shell is an appearance component of the first box body 110 .

[0136] The first box body 110 may include a first box liner 111, and the first box liner 111 is configured to form a storage chamber 101. The first box liner 111 is fixed inside the first box shell. An installation chamber is formed between the first box liner 111 and the first box shell to install other functional components of the freezing device, such as a refrigeration system, a driving device, etc.

[0137] The first box body 110 may include a first heat-insulating member, which is arranged between the first box shell and the first box liner 111 to keep the storage cavity 101 warm. The first heat-insulating member includes a foaming structure, a heat-insulating board, and the like.

[0138] In some embodiments, the box assembly 100 includes a second box 120, and the second box 120 is configured to form a buffer cavity 102 and a first access opening 103. The second box 120 is located on the side of the first box 110. Figure 1 As shown, the second box body 120 is located on one side of the first box body 110 along the longitudinal direction, wherein the longitudinal direction may correspond to Figure 1 The middle Y axis direction.

[0139] The second box body 120 may include a second box shell, and the second box shell is an appearance component of the second box body 120 .

[0140] The second box body 120 may include a second box liner 121, and the second box liner 121 is configured to form a cache chamber 102. The second box liner 121 is fixed inside the second box shell. An installation cavity is formed between the second box liner 121 and the second box shell to install some other functional components of the freezing device, for example, the sampling mechanism 30.

[0141] The second box body 120 may include a second heat-insulating member, which is arranged between the second box shell and the second box liner 121 to keep the storage cavity 101 warm. The second heat-insulating member includes a foaming structure, a heat-insulating board, and the like.

[0142] Combination Figure 1 In some embodiments, a display device 122 is installed on the second housing to display the storage information of the sample. Currently, the display device 122 may also have a touch function to facilitate the operation of the operator.

[0143] In some embodiments, the second box 120 can be detachably connected to the first box 110. In this way, in an emergency such as a power outage, the first box 110 and the second box 120 can be disassembled and the samples in the first box 110 can be urgently transferred to improve the safety of the freezing device.

[0144] In some embodiments, the first box 110 is further configured to form a first opening, which is in communication with the storage cavity 101. The second cavity is further configured to form at least one second opening, which is configured to be in communication with the cache cavity 102. When the second box 120 is connected to the first box 110, the first opening is opposite to the second opening, and together they form a second access opening 104.

[0145] Continue to refer to Figure 2 and Figure 3 The cache chamber 102 serves as an operating chamber of the sample box 10 . A tube picking mechanism 40 may be disposed in the cache chamber 102 . The tube picking mechanism 40 is configured to select a set sample tube from the sample box 10 .

[0146] A scanning mechanism 50 may be disposed in the buffer chamber 102 , and the scanning mechanism 50 is configured to scan information of the sample tube in the sample box 10 .

[0147] A transfer platform 60 may be disposed in the cache chamber 102 , and the transfer platform 60 is configured to transfer the sample box 10 .

[0148] In some embodiments, the transfer platform 60 is located below the tube picking mechanism 40, and the tube picking mechanism 40 is configured to be arranged along the vertical direction (corresponding to Figure 3 The sample box 10 is raised and lowered (in the Z-axis direction) to select a set sample tube from the sample box 10 on the transfer table 60.

[0149] The scanning mechanism 50, the sample placement mechanism 30 and the second placement port 104 are all located on the side of the transfer platform 60, so that the transfer platform 60 can transfer samples between the scanning station, the first placement port 103 and the second placement port 104. Figure 3 The second loading and unloading opening 104 is located on both sides of the transfer platform 60 along the loading and unloading direction (corresponding to Figure 3 The second direction is perpendicular to the sampling direction.

[0150] exist Figure 4 In the illustrated orientation, the scanning mechanism 50 and the placing mechanism 30 are respectively located on both sides of the transfer platform 60 along the X-axis direction, and the second placing port 104 is located on one side of the transfer platform 60 along the Y-axis direction.

[0151] In some embodiments, the transfer platform 60 is configured to move the sample box 10 in a horizontal plane to transfer the sample box 10 between the sample taking and placing mechanism 30 , the second taking and placing port 104 , the scanning mechanism 50 and the tube picking mechanism 40 .

[0152] The horizontal plane is perpendicular to the vertical plane. The horizontal plane is the plane determined by the lofting direction and the second direction. Figure 4 In the orientation shown, the horizontal plane is the XY plane.

[0153] The transfer platform 60 drives the sample box 10 to move in the horizontal plane, including driving the sample box 10 to move in a certain direction in the horizontal plane, and driving the sample box 10 to rotate in the horizontal plane, that is, to rotate around a rotation axis perpendicular to the horizontal plane.

[0154] In this way, the freezing device of the embodiment of the present application realizes the transfer of the sample box 10 between the four stations of scanning, tube picking, sample taking and placing mechanism 30 and the second taking and placing port 104 by setting up a transfer table 60, which can not only simplify the structural layout in the cache cavity 102, but also improve the transfer efficiency of the sample box 10.

[0155] In some embodiments, the transfer station 60 may include a first moving mechanism configured to drive the sample box 10 to move in a direction within a horizontal plane. Figure 4 In the embodiment, the first moving mechanism is configured to drive the sample box 10 to move along the X-axis direction.

[0156] In some embodiments, the transfer platform 60 may include a rotating mechanism, the output end of which is connected to the first moving mechanism, and the rotating mechanism is configured to drive the first moving mechanism to rotate around a rotation axis, thereby driving the sample box 10 to rotate around the rotation axis, wherein the rotation axis is perpendicular to the horizontal plane.

[0157] Through the above configuration, the transfer platform 60 of some embodiments of the present application drives the sample box 10 to move along one direction of the horizontal plane by setting a first moving mechanism, and drives the first moving mechanism to rotate around the rotation axis by setting a rotating mechanism, thereby driving the sample box 10 to rotate in any direction in the horizontal plane. Through the cooperation of the first moving mechanism and the rotating mechanism, the sample box 10 is driven to move in any direction in the horizontal plane, so as to facilitate the transfer of the sample box 10 between the sample taking and placing mechanism 30, the second taking and placing port 104, the scanning mechanism 50 and the tube picking mechanism 40.

[0158] In some embodiments, the transfer platform 60 may include a second moving mechanism, the output end of the second moving mechanism is connected to the rotating mechanism, and the second moving mechanism is configured to drive the rotating mechanism and the first moving mechanism to move along the sampling direction, thereby driving the sample box 10 to move along the sampling direction. In this way, the moving direction of the second moving mechanism is the same as the telescopic direction of the transfer manipulator 22 in the storage mechanism 20, so that there is a sufficient displacement distance between the transfer platform 60 and the transfer manipulator 22, ensuring that the sample box 10 is smoothly transferred between the transfer platform 60 and the transfer manipulator 22. In addition, the second moving mechanism can also provide sufficient space for the rotation of the rotating mechanism to avoid interference with other components in the cache chamber 102 when the transfer platform 60 rotates.

[0159] The following describes in detail, in conjunction with the accompanying drawings, how the sample box 10 enters and exits the cache chamber 102 through the first access port 103 in some embodiments of the present application.

[0160] The box assembly 100 is structured to form a first access opening 103 so that the sample box 10 can enter and exit the cache chamber 102 through the first access opening 103. The first access opening 103 is opened or closed by providing a first heat preservation door 130.

[0161] In some embodiments, the first thermal insulation door 130 may be located outside the cache cavity 102 , so as to facilitate the opening and closing of the first thermal insulation door 130 and to facilitate setting of the driving structure of the first thermal insulation door 130 .

[0162] Combination Figure 4 and Figure 5 In other embodiments, the first heat preservation door 130 may be located in the cache cavity 102. In this way, the opening of the first heat preservation door 130 does not interfere with the taking and placing of the sample taking and placing mechanism 30.

[0163] In some embodiments, the sampling mechanism 30 is configured to seal the first sampling port 103 first, and then the first heat preservation door 130 opens the first sampling port 103 to input or output the sample box 10 into or out of the buffer chamber 102. This configuration allows the first sampling port 103 to be opened after being sealed by the sampling mechanism 30, thereby ensuring the closedness of the buffer chamber 102, reducing the possibility of cold air leaking out of the buffer chamber 102, and improving the temperature stability of the buffer chamber 102; it can also reduce the possibility of condensation forming water droplets or ice on the edge of the first sampling port 103, and ensure the reliability of opening and closing the first sampling port 103.

[0164] like Figure 5 As shown, the first heat preservation door 130 closes the first access opening 103; Figure 4 , the first heat preservation door 130 opens the first loading and unloading port 103 .

[0165] In some embodiments, the first heat preservation door 130 may be an electric door, and the controller of the freezing device first controls the operation of the sample taking and placing mechanism 30 so that the sample taking and placing mechanism 30 seals the first access opening 103, and then controls the operation of the first heat preservation door 130 to open the first access opening 103. In this way, the first heat preservation door 130 and the sample taking and placing mechanism 30 are independently controlled, which is more accurate.

[0166] In some embodiments, the first heat preservation door 130 has no independent drive, and the sampling mechanism 30 is configured to seal the first access port 103 first, and then drive the first heat preservation door 130 to open the first access port 103. That is, the first heat preservation door 130 is driven by the sampling mechanism 30 to open the first access port 103. In this way, there is no need to set an independent drive for the first heat preservation door 130, which is conducive to cost saving and reducing the installation space occupied by the first heat preservation door 130 in the cache cavity 102; it can also improve the linkage between the sampling mechanism 30 and the first heat preservation door 130, ensure that the first access port 103 is opened after being sealed by the sampling mechanism 30, and improve the stability of the temperature in the cache cavity 102.

[0167] Combine again Figure 4 and Figure 5 The first heat preservation door 130 and the placing mechanism 30 are respectively located at the first placing opening 103 along the vertical direction (corresponding to Figure 4 The first heat preservation door 130 is located above the first access opening 103 on both sides of the first heat preservation door 130 (in the middle Z-axis direction). The first heat preservation door 130 can move downward under its own gravity to close the first access opening 103, which helps to ensure the timeliness of the first heat preservation door 130 closing the first access opening 103. Moreover, the gravity of the first heat preservation door 130 acts on the first access opening 103, which helps to improve the sealing performance of the first heat preservation door 130 for the first access opening 103.

[0168] The sampling mechanism 30 is located below the first access opening 103, and is configured to vertically input or output the sample box 10 into or out of the buffer chamber 102. In this way, the sampling mechanism 30 is located outside the buffer chamber 102, so that the driver of the sampling mechanism 30 does not need to be in a low temperature environment, which is conducive to improving the life of the sampling mechanism 30.

[0169] Of course, this is not a limitation on the arrangement direction of the first heat preservation door 130 and the sample taking and placing mechanism 30. For example, the first heat preservation door 130 and the sample taking and placing mechanism 30 are arranged at intervals on both sides of the first taking and placing opening 103 along the opening and closing direction. Figure 4 and Figure 5 As shown, the switch direction may be the Z-axis direction in the figure; the switch direction may also deviate from the Z-axis direction.

[0170] In some possible implementations, the switching direction may be a direction in a horizontal plane. For example, the switching direction may be along Figure 4 That is, the first heat preservation door 130 and the sample placement mechanism 30 are arranged at intervals on both sides of the first placement opening 103 along the X-axis direction, and the sample placement mechanism 30 is configured to input or output the sample box 10 into or out of the buffer chamber 102 along the X-axis direction.

[0171] Combination Figure 6 In some embodiments, the sample placement mechanism 30 includes a supporting component 200 configured to accommodate the sample box 10 .

[0172] The supporting component 200 may be a recessed structure, which is beneficial to improving the stability of the sample box 10 and reducing the possibility of the sample box 10 falling out during the process of being transported by the sample taking and placing mechanism 30 .

[0173] In some possible embodiments of the present application, combined with Figure 6 and Figure 7 The carrying component 200 includes a carrying platform 210 , and the carrying platform 210 is configured to form a receiving cavity 211 to receive the sample box 10 .

[0174] Continue to refer to Figure 6 The sampling mechanism 30 may further include a sealing component 300, which is sleeved on the outer side of the bearing component 200. The sealing component 300 is configured to seal the first sampling port 103. The sealing component 300 is configured to form a through hole so that the sealing component 300 can be sleeved on the outer side of the bearing component 200.

[0175] The bearing component 200 may further include a connecting member 220, and the connecting member 220 is connected to a side of the bearing platform 210 away from the accommodating cavity 211. Figure 6 In the illustrated orientation, the connecting member 220 is located at the bottom end of the support platform 210 .

[0176] The sealing component 300 is sleeved on the outer side of the connecting member 220 , so that the sealing component 300 can move along with the movement of the bearing component 200 .

[0177] In some embodiments, the support platform 210 may be located above the sealing component 300, that is, the support platform 210 may protrude from the upper surface of the sealing component 300. This arrangement makes the top of the sealing component 300 flat, reducing the possibility of condensation on the sealing component 300 and the first access port 103, which may cause water droplets to gather.

[0178] In other embodiments, in combination Figure 7The upper surface of the sealing component 300 is structured to form a receiving groove 330, so that at least part of the carrier 210 can be received in the receiving groove 330. Such a configuration allows at least part of the carrier 210 to be received in the receiving groove 330 of the sealing component 300, reducing the vertical dimension of the taking and placing mechanism 30 and reducing the installation space occupied by the taking and placing mechanism 30.

[0179] Moreover, when the sealing component 300 seals the first access port 103, at least a portion of the support platform 210 is accommodated in the accommodating groove 330 of the sealing component 300, which can reduce the vertical space occupied by the support platform 210 in the first access port 103, thereby reducing the vertical dimension of the first access port 103 and improving the structural compactness of the cache cavity 102.

[0180] Reference Figure 6 and Figure 7 In some embodiments, the sealing component 300 may include a main body 310, and the main body 310 is sleeved on the outer side of the connecting member 220. Exemplarily, a through hole is provided on the main body 310 so that the main body 310 can be sleeved on the outer side of the connecting member 220.

[0181] The main body 310 may be configured to form a receiving groove 330 to receive the carrier 210 , thereby improving the compactness of the structure of the sample taking and placing mechanism 30 . A through hole is provided on the bottom wall of the receiving groove 330 .

[0182] In some possible implementations, the main body 310 may include a heat insulating portion 312 and a base portion 311, wherein the heat insulating portion 312 is fixed to the top of the base portion 311, and the connection between the two includes but is not limited to screw connection, clamping, bonding, etc. Among them, the heat insulating portion 312 has a large thermal resistance, which is conducive to improving the heat insulating performance of the main body 310; the base portion 311 can improve the structural strength of the main body 310.

[0183] Exemplarily, the heat insulating portion 312 may be a plastic plate, and the base portion 311 may be a metal plate.

[0184] The sealing component 300 may include a sealing portion 320, which is disposed on the main body 310; the sealing portion 320 is configured to seal the first access opening 103. The sealing portion 320 is annular, such as a rectangular ring. The sealing component 300 may be a sealing gasket such as a rubber gasket to improve the reliability of the sealing component 300 sealing the first access opening 103.

[0185] In some embodiments, the top surface of the sealing portion 320 protrudes from the top surface of the main body 310 to ensure that the sealing portion 320 is in contact with the box plate 150 and improve the sealing performance of the sealing component 300 .

[0186] The sample taking and placing member of some embodiments of the present application may further include a driving component 400, and the driving component 400 is connected to the bearing component 200. In some embodiments, the driving component 400 is connected to an end of the connecting member 220 away from the bearing platform 210.

[0187] The driving component 400 is configured to drive the supporting component 200 and the sealing component 300 to move toward the first thermal insulation door 130 at the same time, and when the sealing component 300 seals the first access port 103, drive the supporting component 200 to move so that part of the supporting component 200 drives the sample box 10 to enter and exit the cache cavity 102 through the first access port 103.

[0188] Among them, Figure 5 and Figure 6 In the embodiment, the driving member 400 is configured to drive the bearing member 200 and the sealing member 300 to move vertically toward the first heat preservation door 130 simultaneously.

[0189] When the sealing component 300 seals the first access opening 103 , the driving component 400 is configured to independently drive the supporting component 200 to move vertically, so that a portion of the supporting component 200 enters the cache cavity 102 through the first access opening 103 .

[0190] In some embodiments of the present application, Figures 4 to 6 The box assembly 100 includes a box plate 150, and a first access opening 103 is provided on the box plate 150. For example, the box plate 150 can be arranged on a horizontal plane (corresponding to Figure 5 in the XY plane).

[0191] Combination Figure 4 The first access opening 103 provided on the box plate 150 is a rectangular opening to fit the shape of the sample box 10. This allows the sample box 10 to pass through the first access opening 103 smoothly, and also prevents the first access opening 103 from being too large to affect the reliability of the seal.

[0192] Of course, this is not a limitation on the shape of the first access opening 103 . For example, the first access opening 103 may also be a circular opening.

[0193] In some possible implementations, the first heat-insulating door 130 is covered on the top surface of the box plate 150. In this way, the weight of the first heat-insulating door 130 can be used to press the box plate 150 to seal the first access opening 103; the downward gravity of the first heat-insulating door 130 can also be used to make the first heat-insulating door 130 close the first access opening 103.

[0194] The sample taking and placing mechanism 30 is located below the box plate 150; the driving component 400 drives the bearing component 200 to push the first heat preservation door 130 to move, so that the first heat preservation door 130 opens the first taking and placing opening 103. In this way, the first heat preservation door 130 is pushed open by the sample taking and placing mechanism 30, and the first heat preservation door 130 does not need to be additionally provided with a driving mechanism, which is conducive to simplifying the structure of the first heat preservation door 130.

[0195] Continue to refer to Figure 5 A second guide rail 151 is provided in the buffer chamber 102, and the second guide rail 151 is arranged vertically on the top surface of the box plate 150; a second slider 131 is provided on the first heat preservation door 130, and the second slider 131 is slidably installed on the second guide rail 151. Through the cooperation of the second slider 131 and the second guide rail 151, the first heat preservation door 130 has a high linear motion accuracy when sliding vertically, which is conducive to improving the smoothness of the first heat preservation door 130 sliding vertically.

[0196] Combination Figure 8 and Fig. 9 The first access opening 103 has a first dimension L in the vertical direction. When the sealing component 300 seals the first access opening 103 and the first heat preservation door 130 does not open the first access opening 103 , at least the sample box 10 can be located in the first access opening 103 .

[0197] Combination Fig. 9 and Fig.10 A push piece 132 is provided between the carrying component 200 and the first thermal insulation door 130 so that the carrying component 200 can push open the first thermal insulation door 130 through the push piece 132 to open the first access port 103 ; thereby preventing the sample box 10 and the sample tube from being damaged by abutting against the first thermal insulation door 130 .

[0198] For example, the bottom surface of the first heat preservation door 130 is provided with a resisting member 132. When the first heat preservation door 130 closes the first access opening 103, the resisting member 132 is located in the first access opening 103, and the bottom end of the resisting member 132 is higher than the bottom end surface of the box board 150. Fig. 9 When the sealing component 300 seals the first access opening 103, the support platform 210 has not yet abutted against the abutting member 132. After the support component 200 moves upward for a certain distance, it abuts against the abutting member 132 again, so that the first heat preservation door 130 opens the first access opening 103. In this way, the first access opening 103 can be opened after the sealing component 300 seals the bottom surface of the first access opening 103, thereby improving the reliability of the access mechanism 30.

[0199] The abutting member 132 is configured to abut against the carrier 210, and move upward under the action of the carrier 210 to drive the first heat preservation door 130 to open the first access opening 103. The abutting member 132 abuts against the edge of the carrier 210 to prevent the abutting member 132 from contacting the sample box 10 and damaging the sample box 10 and the sample tube.

[0200] A buffer pad, such as an elastic pad such as a rubber pad or a silicone pad, is arranged between the push member 132 and the supporting platform 210 to ensure soft contact between the push member 132 and the supporting platform 210, which can not only reduce the noise caused by the abutment and collision between the push member 132 and the supporting platform 210, but also help to increase the service life of the push member 132 and the supporting platform 210.

[0201] Combination Figures 8 to 10 , describes the sampling and placing process of the placing mechanism 30 in some embodiments of the present application. Among them, Figures 8 to 10 In the figure, the position above the dotted line is the buffer chamber; the position below the dotted line is the outside atmosphere. The position below the dotted line is connected to the outside atmosphere, which does not mean that the position below the dotted line is located outside the freezing device. The sampling mechanism 30 is installed in the second box 120 and is located in the installation space that is not connected to the buffer chamber.

[0202] like Figure 8 As shown, when the sample box 10 is not taken out or placed, the first heat preservation door 130 contacts the top surface of the box plate 150 to seal the first access opening 103. The cold energy in the cache cavity 102 is isolated from the outside atmosphere to ensure that the temperature in the cache cavity 102 is stable.

[0203] When the sample box 10 needs to be sent into the buffer chamber 102 , the sample box 10 is first placed on the carrying platform 210 .

[0204] Combination Fig. 9 The driving component 400 is configured to drive the bearing component 200 and the sealing component 300 to move toward the first heat preservation door 130, so that the sealing component 300 abuts against the bottom surface of the box plate 150, thereby sealing the first access opening 103. At this time, the top surface of the first access opening 103 is also sealed by the first heat preservation door 130, and the sample box 10 is located in the first access opening 103.

[0205] Combination Fig.10, the driving component 400 is configured to independently drive the bearing component 200 to continue to move upward, and the bearing component 200 abuts against the abutting member 132 to push open the first heat preservation door 130, thereby conveying the sample box 10 into the cache chamber 102. At this time, although the first heat preservation door 130 opens the first access port 103, the sealing component 300 still seals the first access port 103, and the cold air in the cache chamber 102 cannot leak outward in large quantities through the first access port 103, which is conducive to ensuring the stability of the temperature in the cache chamber 102, reducing the temperature fluctuation in the cache chamber 102, and ensuring the storage quality of the sample.

[0206] Moreover, there is not a large amount of outside air entering the cache cavity 102, which is conducive to reducing condensation or even ice on the edge of the first access port 103, and can ensure the reliability of the first insulation door 130 closing the first access port 103, and ensure the smoothness of the first insulation door 130 opening and closing the first access port 103.

[0207] The above Figures 8 to 10 This is the process of transporting the sample box 10 to the buffer chamber 102. When the sample box 10 in the buffer chamber 102 needs to be taken out, the carrier 210 of the sample placement mechanism 30 first enters the buffer chamber 102 and receives the sample box 10; then the carrier 210 is taken out of the buffer chamber 102 with the sample box 10.

[0208] Among them, the sampling mechanism 30 is Figures 8 to 10 During the process, the driving component 400 is first configured to drive the bearing component 200 and the sealing component 300 to move toward the first heat preservation door 130 at the same time; and when the sealing component 300 seals the first access opening 103, the bearing component 200 is driven to move so that the bearing platform 210 of the bearing component 200 enters the cache chamber 102 through the first access opening 103; and then the sample box 10 is transferred from the transfer platform 60 to the bearing platform 210, as shown in FIG. Fig.10 as shown; then follow Fig.10 , Fig. 9 , Figure 8 That is, the driving component 400 is further configured to drive the bearing component 200 to move, so that the bearing platform 210 of the bearing component 200 and the sample box 10 thereon are moved out of the buffer chamber 102 through the first access opening 103; and when the first heat preservation door 130 closes the first access opening 103, the bearing component 200 and the sealing component 300 are driven to move away from the first heat preservation door 130 at the same time.

[0209] Continue to refer to Figure 6 In some embodiments, the connecting member 220 may include: a hollow shaft 221, and the hollow shaft 221 is connected to the supporting platform 210 and the driving component 400 respectively.

[0210] exist Figure 6In the illustrated orientation, the hollow shaft 221 is arranged vertically, and the top end of the hollow shaft 221 is fixedly connected to the support platform 210 , and the connection method includes but is not limited to screw connection, clamping, etc. The bottom end of the hollow shaft 221 is configured to be fixedly connected to the output end of the driving component 400 .

[0211] The connecting member 220 may include a heating element 222 disposed inside the hollow shaft 221 ; the heating element 222 is configured to heat the hollow shaft 221 .

[0212] Combination Fig.10 During the process of taking and placing samples, part of the hollow shaft 221 extends into the cache chamber 102. The temperature in the cache chamber 102 is relatively low. When the carrier 210 is removed from the cache chamber 102, moisture in the outside air is likely to condense on the outer surface of the hollow shaft 221. If the taking and placing mechanism 30 continuously enters the cache chamber 102, the moisture condensed on the outer surface of the hollow shaft 221 will freeze, causing the movement of the carrier 210 relative to the sealing component 300 to be blocked or even unable to move.

[0213] To this end, the connecting component 220 of some embodiments of the present application is provided with a hollow shaft 221 and a heating element 222 is provided inside the hollow shaft 221 to heat the hollow shaft 221 and reduce the water droplets condensed on the outer surface of the hollow shaft 221 .

[0214] Continue to refer to Figure 6 The connecting member 220 may further include a connecting rod 223, on which the heating element 222 is arranged, and the connecting rod 223 is fixed in the hollow shaft 221, so that the heating element 222 can be arranged in the hollow shaft 221 with a larger axial length.

[0215] Exemplarily, the heating element 222 may be a heating wire, and the heating wire is wound around the connecting rod 223 .

[0216] In some possible implementations, the connecting rod 223 can be a screw, which can provide a fixed position for the winding of the heating wire, making the winding of the heating wire more stable, and the screw can also be directly threadedly connected to the structure inside the hollow shaft 221, further improving the convenience of screw installation.

[0217] Combination Figure 6 and Fig.11 In some embodiments, a sealing structure 340 is provided between the sealing component 300 and the connecting member 220 to ensure a seal between the sealing component 300 and the connecting member 220, thereby improving the reliability of the sealing component 300 sealing the first access port 103 and reducing the possibility of cold air in the cache cavity 102 leaking to the outside through the sealing component 300 and the connecting member 220.

[0218] Of course, the sealing component 300 and the connecting member 220 can slide relative to each other in the axial direction, so that the bearing component 200 moves relative to the sealing component 300 after the sealing component 300 seals the first access opening 103 to open the first heat preservation door 130 .

[0219] Exemplarily, the sealing structure 340 includes at least one sealing ring 341 , which is disposed between the sealing component 300 and the connecting member 220 .

[0220] In some embodiments, a first guide structure 600 is disposed between the sealing component 300 and the bearing component 200 , so that the bearing component 200 moves toward the first heat-insulating door 130 along the first guide structure 600 .

[0221] By setting a first guide structure 600 between the sealing component 300 and the supporting component 200, a guiding function is played on the movement of the supporting component 200, thereby improving the linear movement accuracy of the supporting component 200, reducing the situation where the inclination of the supporting component 200 affects the stability of the sample box 10 transportation, and also reducing the situation where the inclination of the supporting component 200 causes the increased friction between the sealing component 300 and the supporting component 200.

[0222] Exemplarily, a linear bearing, such as a flange linear bearing, is provided between the sealing component 300 and the bearing component 200. The linear bearing, as the first guide structure 600, can not only guide the bearing component 200 to move along a straight line, but also simplify the structure of the placing mechanism 30.

[0223] Continue to refer to Fig.11 In some embodiments, the sealing component 300 may further include a first end cover 351, which is fixed to the bottom wall of the accommodating groove 330. The first end cover 351 abuts against the top end of the linear bearing to limit the axial position of the linear bearing.

[0224] In some embodiments, the sealing component 300 may further include a second end cap 352, which is fixed under the bottom wall of the accommodating groove 330. The second end cap 352 abuts against the bottom end of the linear bearing to limit the axial position of the linear bearing.

[0225] In this way, the placement mechanism 30 limits the axial position of the linear bearing by providing the first end cover 351 and the second end cover 352 .

[0226] It can be understood that both the first end cover 351 and the second end cover 352 are provided with through holes so that the connecting member 220 of the bearing component 200 can pass through.

[0227] Continue to refer to Fig.11A sealing ring 341 is disposed between the first end cover 351 and the connecting member 220 to improve the sealing performance between the sealing component 300 and the connecting member 220. The sealing ring 341 is located between the first end cover 351 and the hollow shaft 221.

[0228] A sealing ring 341 is disposed between the second end cover 352 and the connecting member 220 to improve the sealing performance between the sealing component 300 and the connecting member 220. The sealing ring 341 is located between the second end cover 352 and the hollow shaft 221.

[0229] The sealing structure 340 includes a sealing ring 341 disposed between the first end cover 351 and the connecting member 220 , and a sealing ring 341 disposed between the second end cover 352 and the connecting member 220 .

[0230] Continue to refer to Figure 6 and Fig.12 In some embodiments, the end of the hollow shaft 221 away from the carrier 210 is configured to form a first arc surface. The first arc surface allows the bottom end of the hollow shaft 221 to be rotatably connected.

[0231] The sample taking and placing mechanism 30 further includes a connecting structure 500 , which is configured to be connected to an output end of the driving component 400 , so that the driving component 400 can drive the bearing component 200 and the sealing component 300 to move through the connecting structure 500 .

[0232] The connection structure 500 includes: a first connection seat 510 , which is configured to form a second arcuate surface that matches the first arcuate surface, so that the end of the hollow shaft 221 can rotate relative to the first connection seat 510 .

[0233] Exemplarily, the first arc surface is a spherical surface, and the second arc surface is a spherical surface, so that the rotation connection between the hollow shaft 221 and the first connecting seat 510 can be smoother.

[0234] Thus, through the cooperation between the first arc surface and the second arc surface, the bottom end of the hollow shaft 221 can rotate relative to the first connecting seat 510, so as to dynamically adjust the angle between the hollow shaft 221 and the vertical direction and reduce the stress strain at the top end of the hollow shaft 221.

[0235] In some implementations, the bottom end of the hollow shaft 221 is connected to a bearing, such as a spherical bearing, a self-aligning ball bearing, etc. The inner ring 2211 and the outer ring of the bearing are in spherical contact. The inner ring 2211 of the bearing is fixed to the bottom end of the hollow shaft 221, and the outer spherical surface of the inner ring 2211 of the bearing forms a first arc surface. The outer ring of the bearing forms a first connecting seat 510, and the inner spherical surface of the outer ring forms a second arc surface.

[0236] In this way, the bottom end of the hollow shaft 221 is rotated by the bearing to abut against the inclination of the hollow shaft 221 , which is beneficial to reducing the processing cost of the sample taking and placing mechanism 30 and simplifying the structure of the sample taking and placing mechanism 30 .

[0237] Continue to refer to Fig.12 In some embodiments, the connection structure 500 further includes a second connection seat 520 , which is connected to the output end of the driving component 400 , so that the bearing component 200 and the sealing component 300 are moved under the drive of the driving component 400 .

[0238] The second connection seat 520 is configured to form a connection groove 521 to accommodate the first connection seat 510. The second connection seat 520 is configured to limit the position of the first connection seat 510 along the first direction, and has a gap G between the second connection seat 520 and the first connection seat 510 in the first plane.

[0239] The first direction is parallel to the axial direction of the hollow shaft 221, corresponding to Fig.12 The first plane is perpendicular to the axial direction of the hollow shaft 221, and the first plane corresponds to Figure 5 Mid XY plane.

[0240] In the embodiment of the present application, the second connection seat 520 is provided to limit the position of the first connection seat 510 along the first direction, and the first connection seat 510 can move in the connection groove 521 to adjust the position of the hollow shaft 221 .

[0241] In this way, the bottom end of the hollow shaft 221 cooperates with the second arc surface and the first arc surface of the first connecting seat 510, and the movement of the first connecting seat 510 in the first plane offsets the stress and strain caused by processing errors, installation errors, and over-constraints.

[0242] Theoretically, after the assembly of the placement mechanism 30 is completed, the hollow shaft 221 extends vertically. However, due to processing errors, installation errors, and over-constraints, there is a certain angle between the axial direction and the vertical direction of the hollow shaft 221, causing the hollow shaft 221 to tilt. If the bottom end of the hollow shaft 221 is fixedly connected to the second connecting seat 520, due to the vertical constraint of the linear bearing on the hollow shaft 221, there is a large friction force between the hollow shaft 221 and the linear bearing, and a large stress and strain are generated at the bottom end of the hollow shaft 221, affecting the service life of the hollow shaft 221 and the linear bearing.

[0243] To this end, the bottom end of the hollow shaft 221 is provided with a first arc surface and a second arc surface that cooperate with each other, and a gap between the first connecting seat 510 and the second connecting seat 520 in the first plane, so that the bottom end of the hollow shaft 221 floats and rotates relative to the second connecting seat 520, thereby offsetting the stress and strain caused by processing errors, installation errors, and over-constraint, and helping to extend the service life of the hollow shaft 221.

[0244] Continue to refer to Fig.12 The second connection seat 520 includes: a seat body 522; a connection groove 521 is formed on the seat body 522. The seat body 522 is fixedly connected to the output end of the driving component 400.

[0245] The second connection seat 520 further includes a third end cover 523 , which is fixed to the top of the seat body 522 , and the third end cover 523 abuts against the top of the first connection seat 510 to limit the position of the first connection seat 510 along the first direction.

[0246] A limiting step is formed in the connection groove 521 so that the bottom end of the first connection seat 510 abuts against the limiting step. In this way, the limiting step cooperates with the third end cover 523 to limit the position of the first connection seat 510 along the first direction.

[0247] The first connection seat 510 may further include a fourth end cover 524, which is located at the bottom end of the second connection seat 520 and may be fixed to the hollow shaft 221. The fourth end cover 524 is located below the end bearing of the hollow shaft 221 and abuts against the bottom end of the inner ring 2211 of the bearing.

[0248] A limiting shoulder is formed on the hollow shaft 221, and the limiting shoulder abuts against the top end of the inner ring 2211 of the bearing. In this way, the fourth end cover 524 and the limiting shoulder are used to limit the position of the inner ring of the bearing along the first direction.

[0249] Reference Fig.13 In some embodiments, the driving component 400 includes: a first driving mechanism 410 , which is connected to the bearing component 200 ; the first driving mechanism 410 is configured to drive the bearing component 200 to move relative to the sealing component 300 .

[0250] The first driving mechanism 410 may include a first driver, and the first driver provides a driving force for the bearing component 200 to move.

[0251] In some embodiments, the first driving mechanism 410 may be a linear driver, such as a cylinder, a hydraulic cylinder, etc. The first driver drives the bearing component 200 to move vertically relative to the sealing component 300 .

[0252] In other embodiments, the first driving mechanism 410 may be a first motor, which provides driving force for the bearing component 200 to move.

[0253] The first driving mechanism 410 may further include a first transmission assembly, through which the first motor is connected to the bearing component 200. The first transmission assembly is configured to convert the rotation of the first motor into linear movement.

[0254] The first transmission assembly may include a first gear and a first rack that mesh with each other, and the first rack extends vertically. The first gear may be fixedly connected to the output shaft of the first motor, and the first rack may be fixed to the bottom end of the bearing component 200. The first motor drives the bearing component 200 to move vertically through the first gear and the first rack.

[0255] The first transmission assembly may include a first lead screw and a first nut, the first nut being threadedly connected to the first lead screw, and the first lead screw may extend vertically. The first lead screw may be connected to the output shaft of the first motor, and the first nut may be fixed to the bottom end of the bearing member 200. The first motor drives the bearing member 200 to move vertically through the first lead screw and the first nut.

[0256] Continue to refer to Fig.13 In some embodiments, the driving component 400 may include a second driving mechanism 420, which is connected to the first driving mechanism 410; the second driving mechanism 420 is configured to drive the first driving mechanism 410 to move, so as to drive the sealing component 300 and the bearing component 200 to move toward the first thermal insulation door 130, so that the sealing component 300 moves to the sealed first loading and unloading port 103.

[0257] The second driving mechanism 420 may include a second driver, and the second driver provides a driving force for the first driving mechanism 410 to move.

[0258] In some embodiments, the second driving mechanism 420 may be a linear driver, such as a cylinder, a hydraulic cylinder, etc. The second driver drives the first driving mechanism 410 , the sealing component 300 , and the bearing component 200 to move vertically.

[0259] In other embodiments, the second driving mechanism 420 may be a second motor, which provides driving force for the first driving mechanism 410 to move.

[0260] The second driving mechanism 420 may further include a second transmission assembly, through which the second motor is connected to the bearing component 200. The second transmission assembly is configured to convert the rotation of the second motor into linear movement.

[0261] The second transmission assembly may include a second gear and a second rack meshing with each other, the second rack extending vertically. The second gear may be fixedly connected to the output shaft of the second motor, and the second rack may be fixedly connected to the first driving mechanism 410. The second motor drives the first driving mechanism 410 to move vertically through the second gear and the second rack.

[0262] The second transmission assembly may include a second lead screw and a second nut, the second nut being threadedly connected to the second lead screw, and the second lead screw may extend vertically. The second lead screw may be connected to the output shaft of the second motor, and the second nut may be fixedly connected to the first drive mechanism 410. The second motor drives the first drive mechanism 410 to move vertically through the second lead screw and the second nut.

[0263] In some possible implementations of the present application, the placement structure may include a second guide structure to guide the first driving mechanism 410 to move vertically, thereby improving the straightness of the vertical movement of the first driving mechanism 410.

[0264] The second guide structure may include a vertically extending guide rail and a slider cooperating with the guide rail, one of the guide rail and the slider is arranged on the first driving mechanism 410, and the other of the guide rail and the slider may be fixed on a frame or a cavity wall in the cache cavity.

[0265] In some embodiments of the present application, the driving component 400 is independently controlled by setting up two driving mechanisms. The first driving mechanism 410 is configured to independently drive the supporting component 200 to move relative to the sealing component 300, and the second driving mechanism 420 is configured to drive the first driving mechanism 410 to move toward the first thermal insulation door 130, thereby driving the supporting component 200 and the sealing component 300 to move toward the first thermal insulation door 130 together, so that the movement of the sealing component 300 and the independent movement control of the supporting component 200 are more precise.

[0266] Combination Fig.14 In some other embodiments of the present application, the driving component 400 uses a driver to first drive the bearing component 200 and the sealing component 300 to move together, and then drives the bearing component 200 to move alone.

[0267] like Fig.14 As shown, the driving component 400 includes: an elastic member 430 which is sleeved on the outer side of the bearing component 200 and located between the sealing component 300 and the connecting end of the bearing component 200 .

[0268] The elastic member 430 is sleeved on the outer side of the hollow shaft 221. Fig.14 In the figure, the elastic member 430 is schematically illustrated as a spring, but this is not a limitation to the elastic member 430. For example, the elastic member 430 may also be an elastic sleeve.

[0269] The driving component 400 may further include a third driving mechanism 440 , which is connected to the connection end of the bearing component 200 to provide driving force for the movement of the bearing component 200 and the sealing component 300 .

[0270] The third driving mechanism 440 may include a third driver, and the third driver provides a driving force for the bearing member 200 and the sealing member 300 to move.

[0271] In some embodiments, the third driving mechanism 440 may be a linear driver, such as a cylinder, a hydraulic cylinder, etc. The third driver drives the bearing component 200 and the sealing component 300 to move vertically.

[0272] In other embodiments, the third driving mechanism 440 may be a third motor, and the third motor provides driving force for the bearing component 200 and the sealing component 300 to move.

[0273] The third driving mechanism 440 may further include a third transmission assembly, through which the third motor is connected to the bearing component 200. The third transmission assembly is configured to convert the rotation of the third motor into linear movement.

[0274] The third transmission assembly may include a third gear and a third rack meshing with each other, and the third rack extends vertically. The third gear may be fixedly connected to the output shaft of the third motor, and the third rack may be fixed to the bottom end of the bearing component 200. The third motor drives the bearing component 200 to move vertically through the third gear and the third rack.

[0275] The third transmission assembly may include a third lead screw and a third nut, the third nut is threadedly connected to the third lead screw, and the third lead screw may extend vertically. The third lead screw may be connected to the output shaft of the third motor, and the third nut may be fixed to the bottom end of the bearing member 200. The third motor drives the bearing member 200 to move vertically through the third lead screw and the third nut.

[0276] In an embodiment of the present application, the third driving mechanism 440 is configured to drive the sealing component 300 and the supporting component 200 to move toward the first thermal insulation door 130 through the elastic member 430; and when the sealing component 300 seals the first access port 103, the supporting component 200 is driven to move so as to enter the cache cavity 102 through the first access port 103.

[0277] Combination Figures 15 to 17 , describes the sampling and placing process of the placing mechanism 30 in some embodiments of the present application. Among them, Figures 15 to 17In the figure, the position above the dotted line is the buffer chamber; the position below the dotted line is the outside atmosphere. The position below the dotted line is connected to the outside atmosphere, which does not mean that the position below the dotted line is located outside the freezing device. The sampling mechanism 30 is installed in the second box 120 and is located in the installation space that is not connected to the buffer chamber.

[0278] Reference Fig.15 When the sample box 10 is not taken out or placed, the first heat preservation door 130 contacts the top surface of the box plate 150 to seal the first access opening 103. The cold energy in the cache cavity 102 is isolated from the outside atmosphere, ensuring that the temperature in the cache cavity 102 is stable.

[0279] When the sample box 10 needs to be sent into the buffer chamber 102 , the sample box 10 is first placed on the carrying platform 210 .

[0280] Combination Fig.16 , the third driving mechanism 440 is configured to drive the bearing component 200 to move toward the first heat preservation door 130, thereby compressing the elastic member 430, until the elastic force of the elastic member 430 is greater than the sum of the gravity in the sealing component 300 and the friction with other components, and the elastic member 430 moves toward the first heat preservation door 130 against the sealing component 300, until the sealing component 300 abuts against the box plate 150, thereby sealing the first access opening 103. At this time, the top surface of the first access opening 103 is still sealed by the first heat preservation door 130, and the sample box 10 is located in the first access opening 103. The elastic member 430 is in a compressed state.

[0281] Combination Fig.17 The third driving mechanism 440 is configured to continue to drive the supporting component 200 to continue to move upward, and the elastic component 430 is continuously compressed, so that the supporting component 200 can move relative to the sealing component 300 until the supporting component 200 abuts against the abutting component 132 to push open the first thermal insulation door 130, thereby transporting the sample box 10 into the cache chamber 102.

[0282] The above Figures 15 to 17 It is a process of conveying the sample box 10 to the cache chamber 102. When it is necessary to take out the sample box 10 in the cache chamber 102, the sample taking and placing mechanism 30 is operated according to Figures 15 to 17 During the process, the carrier 210 enters the cache chamber 102; then the sample box 10 is transferred from the transfer station 60 to the carrier 210, such as Fig.17 as shown; then follow Fig.17 , Fig.16 , Fig.15 That is, the process of outputting the sample box 10 is opposite to the process of conveying the sample box 10, and will not be described in detail here.

[0283] In some embodiments of the present application, the driving component 400 can drive the sealing component 300 and the supporting component 200 to move vertically simultaneously by setting a driver and cooperating with the elastic member 430, and can also drive the supporting component 200 to move vertically relative to the sealing component 300 alone, which is helpful to simplify the structure of the driving component 400 and reduce the cost of the driving component 400.

[0284] Continue to refer to Fig.14 In some embodiments, the sealing component 300 may further include a first sleeve portion 360, which is connected to a side of the main body 310 away from the sealing component 300. The first sleeve portion 360 is configured to form a channel, and the channel is coaxially arranged with the through hole on the main body 310. The hollow shaft of the connecting member 220 is inserted through the through hole and the first sleeve portion 360.

[0285] In this way, the cooperation between the first sleeve portion 360 and the hollow shaft helps to improve the linear accuracy of the vertical movement of the bearing component 200.

[0286] One end of the first sleeve portion 360 facing away from the main body portion 310 abuts against the elastic member 430 so that the elastic force acts on the sealing component 300 .

[0287] The connection end of the bearing component 200 is configured to form a shoulder, and for example, the bottom end of the hollow shaft is configured to form a shoulder. The shoulder abuts against the bottom end of the elastic member 430 , so that the elastic member 430 is located between the connection end of the bearing component 200 and the first sleeve portion 360 .

[0288] Continue to refer to Fig.14 The box assembly 100 may further include a mounting plate 160 for supporting at least a portion of the sample taking and placing mechanism 30. The mounting plate 160 is disposed in the second box 120 and is located outside the buffer cavity.

[0289] The mounting plate 160 may be disposed parallel to the bottom of the box plate 150 to facilitate supporting the bearing component 200 and the sealing component 300 .

[0290] In some embodiments, a mounting hole is provided on the mounting plate 160 so that the first sleeve portion 360 passes through the mounting hole. The main body 310 and the sealing portion 320 of the sealing component 300 are located above the mounting plate 160, and the main body 310 contacts the top surface of the mounting plate 160, which plays a role in limiting the sealing portion 320 and the main body 310 and the carrier 210 in the vertical direction, and can prevent the sealing portion 320, the main body 310 and the carrier 210 from compressing the elastic member 430 under the action of gravity, thereby affecting the service life of the elastic member 430. In addition, due to the supporting effect of the mounting plate 160 on the main body 310, the carrier 210 is stable, which is convenient for placing the sample box 10.

[0291] In some embodiments, a second sleeve portion 161 is fixed below the mounting plate 160, and the second sleeve portion 161 is coaxially arranged with the mounting hole so that the second sleeve portion 161 can be sleeved on the outside of the first sleeve portion 360. The second sleeve portion 161 is provided to provide a linear guide for the vertical movement of the sealing component 300, thereby improving the linear accuracy of the vertical movement of the sealing component 300.

[0292] In some implementations, in combination Fig.16 and Fig.17 The outer diameter of the elastic member 430 is less than or equal to the inner diameter of the second sleeve portion 161, so that the elastic member 430 can move into the second sleeve portion 161 when compressed, providing guidance for the vertical compression deformation of the elastic member 430 and reducing the instability caused by the vertical skewness of the elastic member 430.

[0293] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit it. Although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present application.

[0294] For the convenience of explanation, the above description has been made in conjunction with specific embodiments. However, the above exemplary discussion is not intended to be exhaustive or limit the embodiments to the specific forms disclosed above. Based on the above teachings, various modifications and variations can be obtained. The selection and description of the above embodiments are to better explain the principles and practical applications, so that those skilled in the art can better use the embodiments and various different variations of the embodiments suitable for specific use considerations.

Claims

1. A freezing device, characterized in that: include: The box assembly (100) is constructed as follows: A buffer chamber (102) configured to store a sample box (10); The first access opening (103) is configured to connect the buffer chamber (102) and the outside atmosphere; A first heat-insulating door (130) configured to open and close the first access opening (103); A sample taking and placing mechanism (30) is configured to input or output the sample box (10) into or out of the buffer chamber (102) through a first taking and placing port (103); The sampling mechanism (30) comprises: A carrying component (200) configured to accommodate a sample box (10); A sealing component (300) sleeved on the outer side of the bearing component (200); A driving component (400) connected to the bearing component (200); When the sample box (10) is input into the cache chamber (102), the driving component (400) is configured to drive the bearing component (200) and the sealing component (300) to move toward the first heat preservation door (130) at the same time, and when the sealing component (300) seals the first access opening (103), the bearing component (200) is driven to move, so that part of the bearing component (200) drives the sample box (10) to enter the cache chamber (102) through the first access opening (103).

2. The freezing device according to claim 1, characterized in that: The box assembly (100) comprises a box plate (150), and a first access opening (103) is provided on the box plate (150); The first heat-insulating door (130) is located in the buffer cavity (102) and covers the top surface of the box plate (150); The sampling mechanism (30) is located below the box plate (150); the driving component (400) drives the bearing component (200) to push the first heat preservation door (130) to move, so that the first heat preservation door (130) opens the first sampling opening (103).

3. The freezing device according to claim 1, characterized in that: The bearing component (200) comprises: A carrying platform (210) is structured to form a receiving cavity (211) for receiving the sample box (10); A connecting member (220) is connected to a side of the supporting platform (210) away from the accommodating cavity (211); an end of the connecting member (220) away from the supporting platform (210) is connected to the driving component (400); The sealing component (300) is sleeved on the outer side of the connecting member (220).

4. The freezing device according to claim 3, characterized in that: The connecting member (220) comprises: A hollow shaft (221), the hollow shaft (221) is connected to the bearing platform (210) and the driving component (400) respectively; The heating element (222) is arranged inside the hollow shaft (221); the heating element (222) is configured to heat the hollow shaft (221).

5. The freezing device according to claim 4, characterized in that: The end portion of the hollow shaft (221) facing away from the bearing platform (210) is structured to form a first arc-shaped surface; The sample taking and placing mechanism (30) further comprises a connecting structure (500), and the connecting structure (500) comprises: A first connecting seat (510) is configured to form a second arc-shaped surface that matches the first arc-shaped surface; The second connecting seat (520) is connected to the output end of the driving component (400); the second connecting seat (520) is structured to form a connecting groove (521) to accommodate the first connecting seat (510); the second connecting seat (520) is structured to limit the position of the first connecting seat (510) along a first direction, and has a gap between the second connecting seat (520) and the first connecting seat (510) in a first plane; wherein the first direction is parallel to the axial direction of the hollow shaft (221), and the first plane is perpendicular to the axial direction of the hollow shaft (221).

6. The freezing device according to claim 3, characterized in that: A sealing structure (340) is provided between the sealing component (300) and the connecting member (220).

7. The freezing device according to claim 3, characterized in that: The sealing component (300) comprises: The main body (310) is sleeved on the outer side of the connecting member (220); The sealing portion (320) is arranged on the main body (310); the sealing portion (320) is configured to seal the first taking-in and putting-out opening (103).

8. The freezing device according to any one of claims 1 to 7, characterized in that: A first guide structure (600) is provided between the sealing component (300) and the bearing component (200) so that the bearing component (200) moves along the first guide structure (600) toward the first heat-insulating door (130).

9. The freezing device according to any one of claims 1 to 7, characterized in that: The driving component (400) comprises: A first driving mechanism (410) connected to the bearing component (200); the first driving mechanism (410) is configured to drive the bearing component (200) to move relative to the sealing component (300); The second driving mechanism (420) is connected to the first driving mechanism (410); the second driving mechanism (420) is configured to drive the first driving mechanism (410) to move, so as to drive the bearing component (200) and the sealing component (300) and the first heat-insulating door (130) to move, so as to move the sealing component (300) to the sealed first loading and unloading port (103).

10. The freezing device according to any one of claims 1 to 7, characterized in that: The driving component (400) comprises: An elastic member (430) is sleeved on the outside of the bearing member (200) and is located between the sealing member (300) and the connection end of the bearing member (200); The third driving mechanism (440) is connected to the connection end of the supporting component (200), and is configured to drive the sealing component (300) and the supporting component (200) to move toward the first heat-insulating door (130) through the elastic member (430); and when the sealing component (300) seals the first access opening (103), the third driving mechanism (440) drives the supporting component (200) to move, so that a part of the supporting component (200) drives the sample box (10) to enter and exit the cache chamber (102) through the first access opening (103).

11. A freezing device, characterized in that: include: The box assembly (100) is constructed as follows: A buffer chamber (102) configured to store a sample box (10); The first access opening (103) is configured to connect the buffer chamber (102) and the outside atmosphere; A first heat-insulating door (130) configured to open and close the first access opening (103); The sampling mechanism (30) is configured to input or output the sample box (10) into or out of the cache chamber (102) through the first sampling port (103); and is configured to first seal the first sampling port (103), and then drive the first heat preservation door (130) to open the first sampling port (103), so as to input or output the sample box (10) into or out of the cache chamber (102).

12. A freezing device, characterized in that: include: The box assembly (100) is constructed as follows: A buffer chamber (102) configured to store a sample box (10); The first access opening (103) is configured to connect the buffer chamber (102) and the outside atmosphere; A first heat-insulating door (130) configured to open and close the first access opening (103); A sample taking and placing mechanism (30) is configured to input or output the sample box (10) into or out of the buffer chamber (102) through a first taking and placing port (103); The sampling mechanism (30) comprises: A carrying component (200) configured to accommodate a sample box (10); A sealing component (300) sleeved on the outer side of the bearing component (200); A driving component (400) connected to the bearing component (200); When the sample box (10) in the buffer chamber (102) is output, The driving component (400) is first configured to drive the bearing component (200) and the sealing component (300) to move toward the first heat preservation door (130) at the same time; and when the sealing component (300) seals the first access opening (103), the bearing component (200) is driven to move so that a portion of the bearing component (200) enters the cache chamber (102) through the first access opening (103) and receives the sample box (10); The driving component (400) is further configured to drive the bearing component (200) to move, so that part of the bearing component (200) and the sample box (10) thereon are moved out of the cache chamber (102) via the first access opening (103); and when the first thermal insulation door (130) closes the first access opening (103), the bearing component (200) and the sealing component (300) are driven to move away from the first thermal insulation door (130) at the same time.

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