Pseudo-ginseng coffee and preparation method thereof

Abstract

The invention relates to the technical field of natural resource development and utilization, in particular to pseudo-ginseng coffee and a preparation method thereof. The method comprises the following steps: drying a coffee extract, and carrying out dry granulation to obtain coffee extract particles; and mixing the coffee extract particles, the pseudo-ginseng polysaccharide extract and the pregelatinized starch, and performing dry granulation to obtain the pseudo-ginseng coffee. The method comprises the following steps: decocting Yunnan small coffee beans with water to obtain a coffee extract; adding an ethanol solution into the pseudo-ginseng powder, and carrying out hot-dipping extraction to obtain medicine residues; adding a culture solution and bacillus cereus, carrying out fermentation culture, adding ethanol, and carrying out microwave-assisted extraction to obtain medicine residues; and adding purified water, carrying out microwave-assisted extraction, alcohol precipitation treatment and deproteinization treatment, and concentrating to obtain the panax notoginseng polysaccharide extract. According to the technical scheme, the technical problems that in the prior art, panax notoginseng coffee is low in variety richness degree and cannot meet the requirements of consumers can be solved, and the panax notoginseng coffee has ideal application and popularization prospects.

Description

Technical Field

[0001] The invention relates to the technical field of development and utilization of natural resources, and in particular to notoginseng coffee and a preparation method thereof. Background Art

[0003] Chinese patent CN1313013C provides Panax notoginseng instant coffee and its production and preparation method, which is a health food prepared with Panax notoginseng extract and coffee extract as main raw materials, and the composition is 20%-30% coffee extract, 6%-10% Panax notoginseng extract, 5%-10% maltodextrin, 55%-65% sucrose powder, 2%-5% sodium cyclamate, 1%-2% honey, and 0.2%-0.5% coffee essence. The method uses modern extraction technology to extract coffee and Panax notoginseng, and then clarifies the extract in water to remove macromolecular substances such as collagen and crude protein in the extract, which can effectively improve its solubility, so that the human body can better absorb the health and nutritional components therein; and effectively reduce pesticide residues, expand and increase the biological resource utilization of raw materials, reduce production costs, and enhance the efficacy of the product. Panax notoginseng coffee products in the prior art all perform simple extraction operations on Panax notoginseng, and do not further purify the Panax notoginseng components, resulting in a relatively complex composition in the Panax notoginseng extract used for product preparation. The saponins and other effective ingredients in Panax notoginseng can improve the hypoxia of heart and brain tissues and have a good effect in anti-fatigue health care. This patented technology uses the hypoxia resistance of Panax notoginseng and coffee to develop a health food that can improve the hypoxia of heart and brain tissues. However, not all consumer groups have the above needs, and Panax notoginseng also has other active ingredients with other effects. For example, Panax notoginseng polysaccharide is a bioactive ingredient extracted from the traditional Chinese medicine Panax notoginseng. Panax notoginseng polysaccharide can improve the phagocytic function of macrophages, increase the intracellular lysozyme content, enhance the activity of antibody secreting cells, and improve the body's immune function. Therefore, the variety of Panax notoginseng coffee currently on the market is relatively low and cannot meet the needs of consumers. Summary of the invention

[0004] The purpose of the present invention is to provide a method for preparing Panax notoginseng coffee to solve the technical problem that the Panax notoginseng coffee in the prior art has a low variety and cannot meet the needs of consumers.

[0005] To achieve the above purpose, the technical solution adopted by the present invention is as follows:

[0006] A method for preparing Panax notoginseng coffee, comprising drying a coffee extract extract and then performing dry granulation to obtain coffee extract particles; mixing the coffee extract particles, Panax notoginseng polysaccharide extract extract and pregelatinized starch, and then performing dry granulation to obtain Panax notoginseng coffee;

[0007] The coffee extract is prepared by the following method: Yunnan small-grain coffee beans are roasted and crushed into coarse particles, and then boiled and extracted to obtain an extract; the extract is concentrated and allowed to stand, then filtered, and then concentrated to obtain the coffee extract;

[0008] The Panax notoginseng polysaccharide extract is prepared by the following method: adding ethanol solution to Panax notoginseng powder, and obtaining medicinal residue I after hot extraction; adding culture medium and Bacillus cereus to medicinal residue I to obtain a fermentation system, adding ethanol after fermentation culture, and obtaining medicinal residue II after microwave-assisted extraction; adding pure water to medicinal residue II, and obtaining an extract after microwave-assisted extraction; the extract is concentrated into Panax notoginseng polysaccharide extract after alcohol precipitation and protein removal.

[0009] Furthermore, in the preparation process of the coffee extract, the water decoction extraction is performed twice, each time for 1 hour; the amount of water used for each water decoction extraction is 8 times the mass of Yunnan small-grain coffee beans; the extract is concentrated to a quarter of the original volume and then allowed to stand for 4 hours, then filtered through a 300-mesh sieve, and then concentrated to a coffee extract with a relative density of 1.1.

[0010] Furthermore, in the preparation process of Panax notoginseng polysaccharide extract, an ethanol solution with a volume fraction of 80% was added to Panax notoginseng powder, and the dosage ratio of 80% ethanol solution to Panax notoginseng medicinal material was 6L:1kg. After hot soaking extraction at 70°C for 3h, medicinal residue I was obtained.

[0011] Furthermore, in the process of preparing the notoginseng polysaccharide extract, culture solution and Bacillus cereus are added to the medicinal residue I to obtain a fermentation system; the amount of culture solution added is 3L of culture solution per 1kg of notoginseng medicinal material, and the inoculation amount (mass) of Bacillus cereus is 10% of the mass of the fermentation system; the composition of the culture solution is 1.50g / L of diammonium hydrogen citrate, 0.30g / L of magnesium sulfate, 1.50g / L of dipotassium hydrogen phosphate and 4.00g / L of sodium acetate;

[0012] After fermentation and cultivation at 37°C and 100 rpm shaking for 72 hours, ethanol was added until the volume fraction of ethanol was 20%; after microwave-assisted extraction at a power of 200 W and a frequency of 915 MHz for 15 minutes, medicinal residue II was obtained.

[0013] Further, pure water was added to the residue II, and the amount of pure water was 6 L of pure water per 1 kg of Panax notoginseng medicinal material; after microwave-assisted extraction at a power of 200 W and a frequency of 915 MHz for 15 min, an extract was obtained;

[0014] The extract was centrifuged at 8000 rpm for 30 min to obtain the supernatant, and the supernatant was concentrated to one fifth of the original volume by evaporation under reduced pressure, and anhydrous ethanol was added dropwise until the final concentration of ethanol was 80%, and the mixture was placed in a refrigerator at 4°C for 12 h, and then filtered to obtain the crude Panax notoginseng polysaccharide;

[0015] The crude Panax notoginseng polysaccharide was dispersed in water at a solid-liquid ratio of 1g:5mL, and then 3 times the volume of an organic solvent consisting of chloroform and n-butanol in a volume ratio of 5:1 was added. After shaking, the mixture was allowed to stand to separate the layers. After phase separation, the aqueous phase was taken; and then concentrated to a Panax notoginseng polysaccharide extract with a relative density of 1.1.

[0016] Furthermore, the moisture content of the coffee extract after drying is less than 5%.

[0017] Furthermore, the parameters of the two dry granulation processes were: pressure 3.5 T / cm 2 , sieve aperture 80 mesh.

[0018] Furthermore, the mass ratio of coffee extract extract, Panax notoginseng polysaccharide extract extract and pregelatinized starch is 4-6:1:1.

[0019] The technical solution also provides instant Panax notoginseng coffee obtained by a preparation method of Panax notoginseng coffee.

[0020] Furthermore, the angle of repose of instant Panax notoginseng coffee is less than 40°.

[0021] The technical principle and beneficial effects of this technical solution are:

[0022] This technical solution innovatively uses Panax notoginseng polysaccharide and coffee water extract as core raw materials to carefully develop a unique Panax notoginseng coffee. This product can not only dissolve quickly in hot water, retaining the rich and mellow aroma and flavor of coffee, but also has significant health benefits due to its specially added Panax notoginseng polysaccharide. The characteristics of this patented product are:

[0023] Solubility and taste: Sanqi coffee is designed to be instant and can be dissolved instantly in hot water, ensuring that each cup can be prepared quickly while maintaining the original rich aroma of coffee, meeting consumers' dual needs for convenience and deliciousness.

[0024] Health benefits: The notoginseng polysaccharide ingredients added through scientific proportions can effectively enhance the body's immunity. Studies have shown that notoginseng polysaccharide can significantly improve the phagocytic ability of macrophages, increase the content of lysozyme in cells, and activate antibody-secreting cells, thereby strengthening the human immune system in all aspects. This notoginseng coffee is rich in the antioxidant notoginseng polysaccharide, which helps to remove free radicals in the body, delay the cell aging process, protect the body from oxidative stress damage, and maintain overall health.

[0025] Production process advantages: This solution pays special attention to the optimization of the physical properties of the product to ensure that Panax notoginseng coffee has excellent fluidity. This feature makes it very suitable for large-scale industrial production, which not only improves production efficiency but also ensures the consistency of product quality. The key technical points to achieve fluidity enhancement are: the preparation and purification process of Panax notoginseng polysaccharide extract, the reasonable granulation process and the use of pregelatinized starch.

[0026] Quality Assurance: During the research and development process, we strictly follow food safety standards, select high-quality raw materials, and undergo precision processing to ensure that the final product is both safe and effective. Whether it is for daily drinking or as a functional food supplement, Panax notoginseng coffee is an ideal choice.

[0027] In summary, the Panax notoginseng coffee produced by this technical solution combines the essence of traditional Chinese medicinal material Panax notoginseng with the essence of modern coffee culture, not only providing a novel and convenient beverage choice, but also integrating the concept of health and wellness into it, aiming to bring a richer life experience to consumers. This solution also realizes the further development and utilization of Yunnan's unique plant resources. DETAILED DESCRIPTION

[0028] The present invention is further described in detail below in conjunction with examples, but the embodiments of the present invention are not limited thereto. Unless otherwise specified, the technical means used in the following examples and experimental examples are conventional means well known to those skilled in the art, and the materials, reagents, etc. used can be obtained from commercial sources.

[0029] Example 1

[0030] (1) Preparation of coffee extract:

[0031] Take Yunnan small-grain coffee beans, roast them until brown, crush them into coarse particles (pass through a 40-mesh sieve), use 8 times the weight of the coffee beans to decoct and extract the coarse particles twice, each time for 1 hour, and combine the extracts after the extraction is completed. Concentrate the combined extracts to a quarter of the original volume, and then let them stand at room temperature for 4 hours. Take the supernatant and pass it through a 300-mesh sieve, and concentrate it under reduced pressure to a coffee extract with a relative density of about 1.1.

[0032] (2) Preparation of Panax notoginseng polysaccharide extract:

[0033] The extraction of Panax notoginseng polysaccharide was carried out with reference to the inventor's prior patent technology (CN112656829B A method for simultaneously extracting Panax notoginseng saponins, Panax notoginseng flavonoids and Panax notoginseng polysaccharide and its application), but the polysaccharide extraction process was adjusted and improved. The main purpose of adopting this process is to make full use of the various active ingredients of Panax notoginseng medicinal materials and prepare the Panax notoginseng polysaccharide raw materials required for this scheme. The specific operation steps are as follows:

[0034] Take Panax notoginseng medicinal material (dried roots of Panax notoginseng, with moisture content controlled below 10%), crush it and pass it through 40 mesh to obtain Panax notoginseng powder. Add 80% ethanol solution by volume to the Panax notoginseng powder to obtain the first extraction system, and perform hot soaking extraction at 70°C for 3h. The dosage ratio of 80% ethanol solution to Panax notoginseng medicinal material is 6L:1kg. Then filter to obtain extract I and medicinal residue I. Extract I is used to prepare Panax notoginseng total saponins, which is not a required part of this patent and has other uses.

[0035] Take the residue I and add the culture solution and Bacillus cereus 14579), and obtain a fermentation system. The amount of culture solution added is 3L of culture solution for every 1kg of Panax notoginseng medicinal material, and the inoculation amount (mass) of Bacillus cereus is 10% of the mass of the fermentation system (the Bacillus cereus added to the fermentation system is the dry matter of the bacterial cell after the bacterial expansion culture solution is filtered out after expansion culture). The composition of the culture solution is 1.50g / L diammonium hydrogen citrate, 0.30g / L magnesium sulfate, 1.50g / L dipotassium hydrogen phosphate and 4.00g / L sodium acetate. The fermentation system is placed in a 37°C constant temperature shaker (100rpm) and cultured for 72h. After the above fermentation process is completed, ethanol is added to the final fermentation system to obtain a second extraction system. In the second extraction system, the volume fraction of ethanol is 20%. The second extraction system is added to a microwave extraction tank, and microwave-assisted extraction is performed for 15min, with the parameters of: power 200W, frequency 915MHz. Then filter to obtain extract II and medicinal residue II. Extract II is used to prepare Panax notoginseng total flavonoids extract, which is not a required part of this patent and has other uses.

[0036] Purified water was added to the residue II, and the amount of purified water was 6L of purified water per 1kg of Panax notoginseng medicinal materials to obtain the third extraction system. Then the third extraction system was added to the microwave extraction tank, and microwave-assisted extraction was performed for 15 minutes, with the parameters of power 200W and frequency 915MHz. Then the extract III was filtered to obtain the extract, and the extract III was centrifuged (8000rpm, 30min), the supernatant was taken, and the supernatant was evaporated and concentrated to one-fifth of the original volume under reduced pressure, and anhydrous ethanol was added dropwise until the final concentration of ethanol was 80%, and placed in a 4℃ refrigerator for 12h, and then filtered by suction, the filter cake was retained, and the crude Panax notoginseng polysaccharide was obtained. The crude Panax notoginseng polysaccharide was dispersed in water (solid-liquid ratio 1g:5mL), and then 3 times the volume of organic solvent was added to remove protein and other substances. Among them, the organic solvent was chloroform and n-butanol with a volume ratio of 5:1. After shaking, the layers were allowed to stand, and the aqueous phase was taken after phase separation, the protein precipitate was discarded, and then the extract was concentrated under reduced pressure to a Panax notoginseng polysaccharide extract with a relative density of about 1.1. The notoginseng polysaccharide extract was freeze-dried to obtain a dry powder of notoginseng total polysaccharide extract, and the polysaccharide content of the dry powder of notoginseng total polysaccharide extract was detected by anthrone-sulfuric acid method. The extraction rate of notoginseng total polysaccharide = the mass of notoginseng total polysaccharide in notoginseng total polysaccharide extract / the mass of notoginseng medicinal material × 100%. The purity of notoginseng total polysaccharide = the mass of notoginseng total polysaccharide in notoginseng total polysaccharide extract / the mass of notoginseng total polysaccharide extract × 100%. The extraction rate of the notoginseng polysaccharide extract prepared by this method is 5.89%, and the purity is 93.47%.

[0037] (3) Preparation of instant Panax notoginseng coffee:

[0038] The ratio of Panax notoginseng polysaccharide extract to coffee extract is 1:4-6, and in this embodiment, 1:5 is used. The coffee extract is dried to a moisture content of less than 5%, and then the dried coffee extract is added to a dry granulator and granulated at a pressure of 3.5T / cm 2 The dried coffee extract extract was pressed into blocks, and then granulated by a swing granulator with an 80-mesh screen to obtain coffee extract particles. The coffee extract particles, Panax notoginseng polysaccharide extract extract and pregelatinized starch (which complies with the provisions of the four medicinal excipients of the 2020 edition of the Chinese Pharmacopoeia, and is also a common food additive, and its dosage is consistent with that of Panax notoginseng polysaccharide extract) were added to a three-dimensional motion mixer and mixed for 10 minutes. Then, the obtained mixture was dry granulated again (the method is referred to above) to obtain instant Panax notoginseng coffee.

[0039] The antioxidant effect of instant Panax notoginseng coffee was investigated. The free radical scavenging rate experiment specifically adopted the ABTS free radical scavenging method, which is a conventional method in the prior art. Take 0.4 mg of granular instant Panax notoginseng coffee and fully dissolve it in 1 ml of distilled water, and prepare samples for ABTS free radical scavenging rate detection. The free radical scavenging rate of the instant Panax notoginseng coffee obtained in this scheme is 64% (the average value of the measurements of three batches of Panax notoginseng coffee), which has a certain antioxidant effect.

[0040] 10 mg of instant Panax notoginseng coffee was placed in 100 mL of pure water at 60°C. It can be completely dissolved within 30 seconds under stirring conditions (three batches of Panax notoginseng coffee can achieve the above effect), which has an instant effect. Since the instant Panax notoginseng coffee prepared by this scheme will be used for industrial production, the fluidity of the particles is very critical to production efficiency. Therefore, this technical scheme also measures the angle of repose of instant coffee particles. The angle of repose refers to the maximum angle of the natural slope that can be formed by freely stacked granular materials without external interference. The size of the angle of repose reflects the friction and adhesion between particles, and it is an important indicator for evaluating the fluidity of granular materials. A small angle of repose means that the friction between particles is small and the fluidity is good. A large angle of repose means that the friction between particles is large and the fluidity is poor. Materials with an angle of repose between 30° and 40° have good fluidity. Materials with an angle of repose greater than 40° have poor fluidity. If the fluidity of instant coffee is relatively poor, the material is likely to flow poorly during the packaging process, and the amount of packaging may be inconsistent in different packages. According to the test, the angle of repose of the instant coffee particles of the present invention is 38° (the average value of the measurements of three batches of Panax notoginseng coffee), and the fluidity is good, which is suitable for mass production.

[0041] Comparative Example 1

[0042] The technical scheme of this comparative example is basically the same as that of Example 1, except that the difference lies in the preparation method of the notoginseng polysaccharide extract. In this comparative example, after the preparation of the drug residue II, the following treatment method is adopted:

[0043] Purified water was added to the residue II, and the amount of purified water was 6L of purified water per 1kg of Panax notoginseng medicinal materials to obtain the third extraction system. Then the third extraction system was added to the microwave extraction tank, and microwave-assisted extraction was performed for 15 minutes, with the parameters of power 200W and frequency 915MHz. Then the extract III was filtered to obtain the extract, and the extract III was centrifuged (8000rpm, 30min), the supernatant was taken, and the supernatant was evaporated under reduced pressure and concentrated to an extract with a relative density of approximately 1.1, which was used as the Panax notoginseng polysaccharide extract extract for the preparation of Panax notoginseng coffee, and the preparation process of instant Panax notoginseng coffee was the same as that of Example 1. Since the Panax notoginseng polysaccharide extract extract was not subjected to alcohol precipitation and protein removal in this comparative example, the purity of the polysaccharides in the Panax notoginseng polysaccharide extract extract was reduced, and the antioxidant effect of the obtained Panax notoginseng coffee was reduced. In addition, the instant solubility of the obtained Panax notoginseng coffee was slightly poor, and it took about 40s to achieve instant solubility under the same conditions. In addition, the fluidity of the notoginseng coffee was also negatively affected, and the repose angle increased to 46° (the average value of three batches of notoginseng coffee), which was significantly different from the notoginseng coffee obtained in Example 1 (T test, p < 0.05). The extraction and purification method of the notoginseng polysaccharide extract will affect the fluidity of the final instant notoginseng coffee, which was not expected by the inventors before the experiment.

[0044] Comparative Example 2

[0045] The technical solution of this comparative example is basically the same as that of Example 1, except that the difference lies in the preparation method of instant Panax notoginseng coffee. In this comparative example, no pregelatinized starch is added, and the following processing method is used:

[0046] The ratio of Panax notoginseng polysaccharide extract to coffee extract is 1:5. The coffee extract is dried to a moisture content of <5%, and then the dried coffee extract is added to a dry granulator at a pressure of 3.5T / cm 2 The dried coffee extract was pressed into blocks, and then granulated by a swaying granulator with an 80-mesh screen to obtain coffee extract particles. The coffee extract particles and the notoginseng polysaccharide extract were added to a three-dimensional motion mixer and mixed for 10 minutes. Then, the obtained mixture was dry granulated again to obtain instant notoginseng coffee.

[0047] The antioxidant effect and instant solubility of the obtained instant Panax notoginseng coffee are slightly improved compared with the product obtained in Example 1, but the repose angle of the product is greatly increased to 48° (the average value of the three batches of Panax notoginseng coffee), which is significantly different from the Panax notoginseng coffee obtained in Example 1 (T test, p < 0.05). This shows that the addition of pregelatinized starch is very important for ensuring the fluidity of the product. Although the addition of pregelatinized starch will slightly affect the antioxidant performance of the product, the effect is not significant and can be ignored.

[0048] Comparative Example 3

[0049] The technical scheme of this comparative example is basically the same as that of Example 1, except that the difference lies in the preparation method of instant Panax notoginseng coffee. In this comparative example, Panax notoginseng polysaccharide extract, coffee extract and pregelatinized starch are granulated in one step, and the following processing method is adopted:

[0050] The ratio of pregelatinized starch, Panax notoginseng polysaccharide extract and coffee extract was 1:1:5. The coffee extract was dried to a moisture content of <5%, and then the dried coffee extract, pregelatinized starch and Panax notoginseng polysaccharide extract were added to a dry granulator and granulated at a pressure of 3.5 T / cm 2 The dried coffee extract was pressed into blocks, and then granulated by a swing granulator with an 80-mesh screen to obtain instant Panax notoginseng coffee.

[0051] The antioxidant effect and instant effect of the instant notoginseng coffee obtained are consistent with those of the product obtained in Example 1, but the angle of repose of the product is greatly increased to 46° (the average value of three batches of notoginseng coffee), which is significantly different from the notoginseng coffee obtained in Example 1 (T test, p < 0.05). This shows that in the granulation process, it is necessary to divide it into two steps, and cover the pregelatinized starch and notoginseng polysaccharide extract on the outside of the coffee extract particles, so as to ensure the good fluidity of the obtained particles.

[0052] Comparative Example 4

[0053] The inventor initially used a freeze-drying method to make instant Panax notoginseng coffee. The general operating process is: mix the Panax notoginseng polysaccharide extract and the coffee extract extract in proportion, then perform conventional freeze drying, and then crush the freeze-dried product to obtain a freeze-dried powdered product. The antioxidant properties and instant solubility of the obtained product are relatively ideal, but the fluidity of the product is very unsatisfactory, and the angle of repose reaches more than 50°. Due to poor fluidity, the powder may be difficult to evenly fill into a container or mold, resulting in inconsistent product density. During transportation, mixing or filling, the powder is prone to getting stuck or clogging pipes and machine parts. Poor fluidity may lead to dosage deviations, and poor fluidity will increase time and labor costs in the production process. Therefore, dynamic operation is not only costly, but also not suitable for large-scale production. Therefore, the inventor did not adopt this method.

[0054] The above is only an embodiment of the present invention, and the common knowledge such as the known specific structure and characteristics in the scheme is not described in detail here. It should be pointed out that for those skilled in the art, several deformations and improvements can be made without departing from the structure of the present invention, which should also be regarded as the protection scope of the present invention, and these will not affect the effect of the implementation of the present invention and the practicality of the patent. The scope of protection required by this application shall be based on the content of its claims, and the specific implementation methods and other records in the specification can be used to interpret the content of the claims.

Claims

1. A method for preparing Panax notoginseng coffee, characterized in that: The coffee extract extract is dried and then dry-granulated to obtain coffee extract particles; the coffee extract particles, Panax notoginseng polysaccharide extract and pregelatinized starch are mixed and then dry-granulated to obtain Panax notoginseng coffee; The coffee extract is prepared by the following method: Yunnan small-grain coffee beans are roasted and crushed into coarse particles, and then boiled and extracted to obtain an extract; the extract is concentrated and allowed to stand, then filtered, and then concentrated to obtain the coffee extract; The Panax notoginseng polysaccharide extract is prepared by the following method: adding ethanol solution to Panax notoginseng powder, and obtaining medicinal residue I after hot extraction; adding culture medium and Bacillus cereus to medicinal residue I to obtain a fermentation system, adding ethanol after fermentation culture, and obtaining medicinal residue II after microwave-assisted extraction; adding pure water to medicinal residue II, and obtaining an extract after microwave-assisted extraction; the extract is concentrated into Panax notoginseng polysaccharide extract after alcohol precipitation and protein removal.

2. The method for preparing Panax notoginseng coffee according to claim 1, characterized in that: In the preparation process of coffee extract, water decoction extraction is performed twice, each time for 1 hour; the amount of water used for each water decoction extraction is 8 times the mass of Yunnan small-grain coffee beans; the extract is concentrated to a quarter of the original volume and then allowed to stand for 4 hours, then filtered through a 300-mesh sieve, and then concentrated to a coffee extract with a relative density of 1.

1.

3. The method for preparing Panax notoginseng coffee according to claim 1, characterized in that: In the preparation process of Panax notoginseng polysaccharide extract, an ethanol solution with a volume fraction of 80% was added to Panax notoginseng powder, and the dosage ratio of 80% ethanol solution to Panax notoginseng medicinal material was 6L:1kg. After hot soaking extraction at 70°C for 3h, medicinal residue I was obtained.

4. The method for preparing Panax notoginseng coffee according to claim 1, characterized in that: In the process of preparing the notoginseng polysaccharide extract, culture solution and Bacillus cereus are added to the medicinal residue I to obtain a fermentation system; the amount of the culture solution added is 3 L of culture solution per 1 kg of notoginseng medicinal material, and the inoculation amount (mass) of Bacillus cereus is 10% of the mass of the fermentation system; the composition of the culture solution is 1.50 g / L of diammonium hydrogen citrate, 0.30 g / L of magnesium sulfate, 1.50 g / L of dipotassium hydrogen phosphate and 4.00 g / L of sodium acetate; After fermentation and cultivation at 37°C and 100 rpm shaking for 72 hours, ethanol was added until the volume fraction of ethanol was 20%; after microwave-assisted extraction at a power of 200 W and a frequency of 915 MHz for 15 minutes, medicinal residue II was obtained.

5. The method for preparing Panax notoginseng coffee according to claim 1, characterized in that: Purified water was added to the residue II, and the amount of purified water was 6 L for every 1 kg of Panax notoginseng medicinal material; after microwave-assisted extraction at a power of 200 W and a frequency of 915 MHz for 15 min, an extract was obtained; The extract was centrifuged at 8000 rpm for 30 min to obtain the supernatant, and the supernatant was concentrated to one fifth of the original volume by evaporation under reduced pressure, and anhydrous ethanol was added dropwise until the final concentration of ethanol was 80%, and the mixture was placed in a refrigerator at 4°C for 12 h, and then filtered to obtain the crude Panax notoginseng polysaccharide; The crude Panax notoginseng polysaccharide was dispersed in water at a solid-liquid ratio of 1g:5mL, and then 3 times the volume of an organic solvent consisting of chloroform and n-butanol in a volume ratio of 5:1 was added. After shaking, the mixture was allowed to stand to separate the layers. After phase separation, the aqueous phase was taken; and then concentrated to a Panax notoginseng polysaccharide extract with a relative density of 1.

1.

6. The method for preparing Panax notoginseng coffee according to claim 1, characterized in that: The moisture content of the coffee extract after drying is less than 5%.

7. The method for preparing Panax notoginseng coffee according to claim 1, characterized in that: The parameters of the two dry granulation processes are: pressure 3.5T / cm 2 , the sieve aperture is 80 mesh.

8. The method for preparing Panax notoginseng coffee according to claim 7, characterized in that: The mass ratio of the coffee extract extract, the Panax notoginseng polysaccharide extract extract and the pregelatinized starch is 4-6:1:

1.

9. Instant Panax notoginseng coffee obtained according to the preparation method of Panax notoginseng coffee according to any one of claims 1 to 8.

10. The instant Panax notoginseng coffee obtained by the preparation method of Panax notoginseng coffee according to claim 9, characterized in that: The repose angle of instant Panax notoginseng coffee is less than 40°.