Experimental sample grinder for molecular biology

Abstract

The invention discloses an experimental sample grinder for molecular biology, and relates to the technical field of grinders, a switching grinding assembly is arranged on the outer side of a mortar, the top end of a mortar rod is movably clamped to the output shaft end of a grinding motor, the other end of the bottom surface of a horizontal connecting rod is connected with a pull rod, and the bottom end of a guide pipe is fixedly connected to the bottom surface of a supporting seat; the feeding guide rails are installed at the two ends of the feeding hole correspondingly, one end of the feeding plate penetrates through the lifting hole and is connected with the lead screw through a screw hole, the suction cup is installed on one side of the fixed semi-ring in a penetrating mode, the grinding auxiliary assembly is installed in the mortar, and the quantitative cooling assembly is connected to the outer side of the mortar in a sleeving mode. Different structures and processing modes are adopted when the quantity of experimental samples is large or the variety of the experimental samples is large, the quantity is small, the number of used structures is small, carrying and moving are easy, semi-automatic continuous grinding is achieved when the quantity is large, operation is convenient, grinding efficiency is high, and the device is suitable for various different experiments and experimental occasions and wider in application range.

Description

Technical Field

[0001] The invention relates to the technical field of grinders, in particular to a molecular biology experimental sample grinder. Background Art

[0002] Molecular biology experiments are disciplinary practices that study life phenomena and their material basis at the molecular level. They aim to reveal the structure, function and interaction mechanism of biological macromolecules (such as DNA, RNA and protein). When conducting experiments, it is often necessary to extract DNA or RNA from experimental samples. During the extraction process, the experimental samples need to be ground to break up the cells to facilitate subsequent extraction.

[0003] The patent with application number 202321481493.6 mentions "a molecular biology experiment sample grinder". This technical solution can adapt to the grinding of samples of different specifications or quantities, control the uniformity and sufficiency of grinding, reduce sample residue, and thus improve the efficiency of the experiment. However, in actual operation, different samples require different grinding methods, and the amount of samples required for different experiments is also different. The sample amount is small, the above-mentioned device is large in size, not easy to carry, and inconvenient to operate. When grinding different samples continuously, it is necessary to change the grinder multiple times, which is time-consuming and has low grinding efficiency. Summary of the invention

[0004] The present invention provides a molecular biology experimental sample grinder, which can effectively solve the problems raised in the above background technology that different samples need to be ground in different ways in actual operation, and the sample amounts required for different experiments are also different. The sample amount is small, the above device is large in size, not easy to carry, and inconvenient to operate. When continuously grinding different samples, the grinder needs to be changed many times, the operation is time-consuming, and the grinding efficiency is low.

[0005] To achieve the above object, the present invention provides the following technical solutions: A molecular biology experimental sample grinder, comprising a mortar, a switch grinding assembly is arranged on the outer side of the mortar, and the switch grinding assembly comprises a mortar rod;

[0006] The top of the feeding screw is connected to the output shaft end of the grinding motor, the top of the grinding motor is connected to one end of the bottom surface of the horizontal connecting rod, and the other end of the bottom surface of the horizontal connecting rod is connected to a pulling rod, the bottom end of the pulling rod is movably sleeved with a guide tube, and the bottom end of the guide tube is fixedly connected to the bottom surface of the support seat, and the support seat is provided with a feeding hole at the bottom end of the mortar, and feeding guide rails are installed at both ends of the feeding hole. The bottom end of the feeding hole is provided with an embedding groove, and the middle part of the inner side of the feeding hole is provided with a lifting hole. A feeding plate is movably embedded and installed in the embedding groove, one end of the feeding plate passes through the lifting hole and is connected to a feeding screw through a screw hole, and the top end of the feeding screw is connected to the output shaft of the feeding motor, and the feeding motor is installed on one side of the fixed semi-ring, and the fixed semi-ring is fixedly installed on one side of the top of the feeding hole, and a suction cup is installed on one side of the fixed semi-ring;

[0007] A grinding auxiliary component is installed inside the mortar, a quantitative cooling component is sleeved on the outside of the mortar, and an insulating sleeve is sleeved on the outside of the quantitative cooling component. A movable half ring is fixedly installed on one side of the insulating sleeve, a switching tube is fixedly installed in the middle of one side of the movable half ring, a switching rod is movably installed inside the switching tube, the top of the switching rod is fixedly connected to one end of the steering plate, and a clamping tube is movably installed on the other end of the steering plate, and a rotating handle is welded on the top of the clamping tube.

[0008] According to the above technical solution, the grinding auxiliary component includes a grinding head;

[0009] A grinding head is fixedly connected to the bottom end of the mortar rod, an upper baffle is symmetrically fixedly installed on the top of the grinding head, a lower baffle is symmetrically fixedly installed in the middle of the grinding head, grinding balls are placed inside the mortar, a supporting spring is sleeved in the middle of the mortar rod, an end cover is movably sleeved on the top of the mortar rod, a rib is welded on the edge of the end cover, and filling holes are evenly opened on the top surface of the rib.

[0010] According to the above technical solution, the quantitative cooling assembly includes an annular cooling box;

[0011] An annular cooling box is sleeved on the outer side of the mortar, a retaining ring is fixedly installed inside the annular cooling box, extrusion holes are symmetrically opened on the bottom end of the retaining ring, an extrusion ring is movably sleeved on the top end of the retaining ring, a cooling screw is installed on one side of the extrusion ring through a screw hole, the top end of the annular cooling box is abutted against a top cover box, the top end of the cooling screw rotates through the top cover box and is connected to a knob, the bottom surface of the top cover box is aligned with the retaining edge and is provided with an injection hole, a blocking ring is rotatably inlaid on the inner edge of the top end of the top cover box, a right-angle block is fixedly installed at the bottom end of the blocking ring corresponding to the injection hole, a limited position block is provided near the injection hole of the top cover box, and a toggle rod is fixedly installed on one side of the top surface of the blocking ring.

[0012] According to the above technical solution, the inner bottom end of the mortar is rounded, the cross section of the rib is a right angle, and the rib and the top end of the mortar are connected in a transition fit manner.

[0013] According to the above technical solution, the distance between the upper baffle and the lower baffle is smaller than the diameter of the grinding ball, the ends and edges of the upper baffle and the lower baffle are rounded, and the spatial angle between the upper baffle and the lower baffle is 90°.

[0014] According to the above technical solution, a motor tray is installed on one side of the fixed half ring, the feeding motor is installed on the top surface of the motor tray, and the output shaft of the feeding motor movably passes through the motor tray.

[0015] According to the above technical solution, the bottom end of the top cover box cross-section is a hollow right angle, the top end of the retaining ring contacts the inner top surface of the top cover box, the outer side of the shielding ring fits the inner wall of the annular cooling box close to the outer side, and the inner side of the shielding ring fits the outer side of the retaining ring.

[0016] According to the above technical solution, a limiting groove is provided at the bottom of the mortar, an iron strip is embedded at the top of the limiting groove, limiting guide rails are fixedly installed in the middle of the top surface of the feeding guide rail and the feeding plate, and a magnetic strip is bonded to the top surface of the limiting guide rail.

[0017] According to the above technical solution, the input ends of the grinding motor and the feeding motor are electrically connected to the output end of the external power supply respectively, the diameter of the mortar is equal to the diameter of the embedding groove, and the top edge of the embedding groove is chamfered.

[0018] According to the above technical solution, the pull rod is a hexagonal prism, the conduit is a round tube with a regular hexagonal hole in the middle, and the fixed half ring and the movable half ring are spliced ​​into a circular ring shape.

[0019] Compared with the prior art, the present invention has the following beneficial effects:

[0020] 1. A switching grinding component is provided. When the amount to be ground is large or there are many types, the samples are quantitatively distributed and placed in each mortar in turn. The mortars are placed in the feeding guide rail on one side in turn, and the insulation sleeve is placed close to the fixed half ring. The suction cup adsorbs the insulation sleeve on one side to fix the insulation sleeve. The mortar enters the embedding groove, and the feeding plate drives the mortar to be embedded in the annular cooling box. The top end of the mortar rod and the bottom end of the grinding motor are connected and combined. After the grinding is completed, the mortar rod returns to the embedding groove, and the grinding is continuously performed in a semi-automatic manner, which is convenient for the processing of samples with large amounts or many types, and effectively improves the experimental efficiency.

[0021] 2. A grinding auxiliary component is provided. When the amount to be ground is small and cooling is not required, take the mortar and place it on a horizontal operating table, put the experimental sample in the mortar, put in the grinding head and grinding balls, put the end cover on the top of the mortar rod, take the clamping tube, and movably clamp the clamping tube to the top of the mortar rod. Hold the rotating handle and turn it. The grinding head grinds the experimental sample at the bottom of the mortar. During the grinding process, the upper baffle and the lower baffle will alternately hit the grinding balls, and the grinding balls hit the inside of the mortar, vibrating the inside of the mortar. The experimental materials adhered to the inner wall of the mortar slide down to the bottom of the mortar under the multiple effects of impact, vibration and gravity, and continue grinding to ensure sufficient grinding.

[0022] 3. A quantitative cooling component is provided. When cooling is required, an insulating sleeve is sleeved on the outside of the annular cooling box, and liquid nitrogen is poured into the annular cooling box. The rotating cooling screw drives the extrusion ring to move downward, and the extruded liquid nitrogen flows from the extrusion hole at the bottom of the retaining ring, and then is discharged from the injection hole to the top surface of the retaining edge, and flows into the mortar through the filling hole. With the switching rod in the switching tube as the axis, the steering plate is rotated, the clamping tube is aligned with the top end of the mortar rod, and the handle is rotated for grinding. After one grinding is completed, the mortar is pushed out of the annular cooling box, and a new mortar with the experimental sample already placed is put in for grinding again. Quantitative control is convenient for adding liquid nitrogen and saving liquid nitrogen, which improves the convenience of operation;

[0023] In summary, different structures and processing methods can be used according to the needs, when the amount to be ground is small, whether liquid nitrogen cooling is required, and the amount of experimental samples is large, or there are many types. When the amount is small, fewer structures are used and it is easy to carry and move. When the amount is large, semi-automatic continuous grinding is easy to operate and has high grinding efficiency. It is suitable for a variety of different experiments and experimental occasions and has a wider range of applications.

[0024] The grinding auxiliary component relies on the collision of grinding balls to improve the grinding effect while reducing adhesion. The quantitative cooling component facilitates the quantitative addition of liquid nitrogen while reducing the consumption of liquid nitrogen and saving materials. It can be combined with the switching grinding component according to different experimental needs to achieve better and more efficient grinding results. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] The accompanying drawings are used to provide further understanding of the present invention and constitute a part of the specification. They are used to explain the present invention together with the embodiments of the present invention and do not constitute a limitation of the present invention.

[0026] In the attached picture:

[0027] Figure 1 It is a schematic diagram of the structure of the present invention;

[0028] Figure 2 It is a schematic diagram of the structure of the switching grinding assembly of the present invention;

[0029] Figure 3It is a schematic diagram of the installation structure of the suction cup of the present invention;

[0030] Figure 4 It is a schematic diagram of the installation structure of the iron sheet strip of the present invention;

[0031] Figure 5 It is a schematic diagram of the installation structure of the feeding plate of the present invention;

[0032] Figure 6 is a schematic structural diagram of the grinding auxiliary assembly of the present invention;

[0033] Figure 7 It is a schematic diagram of the structure of the quantitative cooling assembly of the present invention;

[0034] Figure 8 It is a schematic diagram of the installation structure of the right-angle stop of the present invention;

[0035] Numbers in the figure: 1, mortar;

[0036] 2. Switching grinding assembly; 201. Bowl rod; 202. Grinding motor; 203. Horizontal connecting rod; 204. Pulling rod; 205. Guide tube; 206. Support seat; 207. Feeding hole; 208. Feeding guide rail; 209. Embedding groove; 210. Lifting hole; 211. Feeding plate; 212. Feeding screw rod; 213. Feeding motor; 214. Fixed half ring; 215. Suction cup; 216. Insulating sleeve; 217. Movable half ring; 218. Switching tube; 219. Switching rod; 220. Steering plate; 221. Card tube; 222. Turning handle;

[0037] 21. Grinding auxiliary assembly; 2101. Grinding head; 2102. Upper baffle; 2103. Lower baffle; 2104. Grinding ball; 2105. Support spring; 2106. End cover; 2107. Retaining edge; 2108. Filling hole;

[0038] 22. Quantitative cooling assembly; 2201. Annular cooling box; 2202. Retaining ring; 2203. Extrusion hole; 2204. Extrusion ring; 2205. Cooling screw; 2206. Top cover box; 2207. Knob; 2208. Injection hole; 2209. Shielding ring; 2210. Right angle stop; 2211. Limit stop; 2212. Toggle lever;

[0039] 3. Motor tray; 4. Limiting groove; 5. Iron strip; 6. Limiting guide rail; 7. Magnetic strip. DETAILED DESCRIPTION

[0040] The preferred embodiments of the present invention are described below in conjunction with the accompanying drawings. It should be understood that the preferred embodiments described herein are only used to illustrate and explain the present invention, and are not used to limit the present invention.

[0041] Example: Figure 1-8As shown, the present invention provides a technical solution of a molecular biology experimental sample grinder, comprising a mortar 1, a switching grinding assembly 2 is arranged on the outer side of the mortar 1, and the switching grinding assembly 2 comprises a mortar rod 201, a grinding motor 202, a horizontal connecting rod 203, a pulling rod 204, a guide tube 205, a support seat 206, a loading hole 207, a feeding guide rail 208, an embedding groove 209, a lifting hole 210, a feeding plate 211, a feeding screw rod 212, a feeding motor 213, a fixed half ring 214, a suction cup 215, a grinding auxiliary assembly 21, a quantitative cooling assembly 22, a heat insulation sleeve 216, a movable half ring 217, a switching tube 218, a switching rod 219, a steering plate 220, a clamping tube 221 and a rotating handle 222;

[0042] A mortar rod 201 is placed inside the mortar 1. The top of the mortar rod 201 is movably connected to the output shaft end of the grinding motor 202. The top of the grinding motor 202 is connected to one end of the bottom surface of the horizontal connecting rod 203. The other end of the bottom surface of the horizontal connecting rod 203 is connected to a pull rod 204. The bottom end of the pull rod 204 is movably sleeved with a guide tube 205. The bottom end of the guide tube 205 is fixedly connected to the bottom surface of a support seat 206. The support seat 206 is located at the bottom end of the mortar 1 and is provided with a feeding hole 207. Both ends of the feeding hole 207 are equipped with feeding guide rails 208. The input ends of the grinding motor 202 and the feeding motor 213 are electrically connected to the output ends of the external power supply respectively. The diameter of the mortar 1 is equal to the diameter of the embedding groove 209. The top edge of the embedding groove 209 is chamfered to facilitate the mortar 1 to enter the embedding groove 209. The bottom end of the feeding hole 207 is provided with an embedding groove 209, and the middle part of the inner side of the feeding hole 207 is provided with a lifting hole 210. A feeding plate 211 is movably embedded in the groove 209, a limiting groove 4 is provided at the bottom end of the mortar 1, an iron strip 5 is inlaid at the top of the limiting groove 4, a limiting guide rail 6 is fixedly installed in the middle of the top surface of the feeding guide rail 208 and the feeding plate 211, a magnetic strip 7 is bonded to the top surface of the limiting guide rail 6, so as to smoothly push the mortar 1 to move, one end of the feeding plate 211 passes through the lifting hole 210 and is connected with a feeding screw rod 212 through a screw hole, the top of the feeding screw rod 212 is connected to the output shaft of the feeding motor 213, a motor tray 3 is installed on one side of the fixed semi-ring 214, the feeding motor 213 is installed on the top surface of the motor tray 3, and the output shaft of the feeding motor 213 movably passes through the motor tray 3, so as to facilitate the installation of the feeding motor 213, the feeding motor 213 is installed on one side of the fixed semi-ring 214, the fixed semi-ring 214 is fixedly installed on one side of the top of the feeding hole 207, and a suction cup 215 is installed through one side of the fixed semi-ring 214;

[0043] A grinding auxiliary component 21 is installed inside the mortar 1, a quantitative cooling component 22 is sleeved on the outside of the mortar 1, and an insulating sleeve 216 is sleeved on the outside of the quantitative cooling component 22. A movable semi-ring 217 is fixedly installed on one side of the insulating sleeve 216. The pull rod 204 is a hexagonal prism, and the guide tube 205 is a round tube with a regular hexagonal hole in the middle. The fixed semi-ring 214 and the movable semi-ring 217 are spliced ​​into a circular ring to prevent the pull rod 204 from rotating freely in the guide tube 205, so as to ensure that the grinding motor 202 is aligned with the center position of the fixed semi-ring 214 and the movable semi-ring 217. A switching tube 218 is fixedly installed in the middle of one side of the movable semi-ring 217, and a switching rod 219 is movably installed inside the switching tube 218. The top of the switching rod 219 is fixedly connected to one end of a steering plate 220, and a clamping tube 221 is movably installed on the other end of the steering plate 220, and a rotating handle 222 is welded on the top of the clamping tube 221.

[0044] The grinding auxiliary assembly 21 includes a grinding head 2101, an upper baffle 2102, a lower baffle 2103, grinding balls 2104, a support spring 2105, an end cover 2106, a rib 2107 and a filling hole 2108;

[0045] The bottom end of the mortar rod 201 is fixedly connected to a grinding head 2101, an upper baffle 2102 is symmetrically fixedly installed on the top of the grinding head 2101, and a lower baffle 2103 is symmetrically fixedly installed in the middle of the grinding head 2101. A grinding ball 2104 is placed inside the mortar 1, and the distance between the upper baffle 2102 and the lower baffle 2103 is smaller than the diameter of the grinding ball 2104. The ends and edges of the upper baffle 2102 and the lower baffle 2103 are rounded, and the spatial angle between the upper baffle 2102 and the lower baffle 2103 is 90°, which is convenient for the upper baffle 2 102 and the lower baffle 2103 push the grinding ball 2104 to continuously collide to assist grinding. A support spring 2105 is sleeved in the middle of the bowl rod 201, and an end cover 2106 is movably sleeved on the top of the bowl rod 201. A rib 2107 is welded on the edge of the end cover 2106. The bottom end of the inner side of the mortar 1 is rounded, and the cross-section of the rib 2107 is a right angle. The rib 2107 and the top of the mortar 1 are connected in a transition fit, which is convenient for embedding the rib 2107 in the mortar 1, and filling holes 2108 are evenly opened on the top surface of the rib 2107.

[0046] The quantitative cooling assembly 22 includes an annular cooling box 2201, a retaining ring 2202, an extrusion hole 2203, an extrusion ring 2204, a cooling screw 2205, a top cover box 2206, a knob 2207, an injection hole 2208, a shielding ring 2209, a right-angle stop 2210, a limit stop 2211 and a toggle rod 2212;

[0047] An annular cooling box 2201 is sleeved on the outside of the mortar 1, a retaining ring 2202 is fixedly installed inside the annular cooling box 2201, and extrusion holes 2203 are symmetrically opened at the bottom of the retaining ring 2202. An extrusion ring 2204 is movably sleeved on the top of the retaining ring 2202, and a cooling screw 2205 is installed on one side of the extrusion ring 2204 through a screw hole. The top of the annular cooling box 2201 is abutted against a top cover box 2206, and the bottom end of the top cover box 2206 has a hollow right angle, the top of the retaining ring 2202 contacts the inner top surface of the top cover box 2206, and the outer side of the extrusion ring 2204 fits the inner wall of the annular cooling box 2201 close to the outside. 04 The inner side fits the outer side of the retaining ring 2202 to facilitate the extrusion ring 2204 to extrude and add liquid nitrogen. The top end of the cooling screw 2205 rotates and passes through the top cover box 2206, which is connected to the knob 2207. The bottom surface of the top cover box 2206 is aligned with the retaining edge 2107 and is provided with an injection hole 2208. The inner edge of the top of the top cover box 2206 is rotatably inlaid with a shielding ring 2209. The bottom end of the shielding ring 2209 is fixedly installed with a right-angle block 2210 corresponding to the injection hole 2208. The top cover box 2206 is provided with a limited stop 2211 near the injection hole 2208, and a toggle rod 2212 is fixedly installed on one side of the top surface of the shielding ring 2209.

[0048] The working principle and use process of the present invention are as follows: select an appropriate grinding structure according to the needs of use. When the amount to be ground is small and does not need to be cooled, take the mortar 1 and place it on a horizontal operating table, put the experimental sample in the mortar 1, put in the grinding head 2101 and the grinding ball 2104, sleeve the end cover 2106 on the top of the mortar rod 201, take the clamping tube 221, and movably clamp the clamping tube 221 on the top of the mortar rod 201, hold the rotating handle 222 and rotate it, the grinding head 2101 grinds the experimental sample at the bottom end of the mortar 1, during the grinding process, the upper baffle 2102 and the lower baffle 2103 will alternately hit the grinding ball 2104, the grinding ball 2104 hits the inner side of the mortar 1, vibrates the inner side of the mortar 1, and the experimental material adhered to the inner wall of the mortar 1 slides down to the bottom end of the mortar 1 under the multiple effects of impact, vibration and gravity, and continues to grind to ensure sufficient grinding;

[0049] When the amount to be ground is small and cooling is required, after the experimental sample, grinding head 2101, grinding head 2101, grinding balls 2104 and end cover 2106 are placed in the mortar 1, the annular cooling box 2201 is sleeved on the outside of the mortar 1, the outer side of the annular cooling box 2201 is sleeved with the insulating sleeve 216, and liquid nitrogen is poured into the annular cooling box 2201, and the top cover box 2206 is quickly installed on the top of the annular cooling box 2201 to slow down the volatilization of liquid nitrogen, the toggle rod 2212 drives the rotating shielding ring 2209 to remove the right-angle block 2210 blocking the injection hole 2208, and the knob 2207 is turned. The rotating cooling screw 2205 drives the extrusion ring 2204 to move downward, and the extruded liquid nitrogen flows from the extrusion hole 2203 at the bottom of the retaining ring 2202, and then is discharged from the injection hole 2208 to the top surface of the retaining edge 2107, and flows into the mortar 1 through the filling hole 2108. To freeze the sample, push the toggle rod 2212 again until the right-angle stop 2210 is blocked by the limit stop 2211 and the injection hole 2208 is closed, so as to facilitate the next freezing of the experimental sample. With the switching rod 219 in the switching tube 218 as the axis, turn the steering plate 220, align the clamping tube 221 with the top of the mortar rod 201, and turn the handle 222 to grind. After one grinding is completed, push the mortar 1 out of the annular cooling box 2201, and put the new mortar 1 equipped with the experimental sample into it for grinding again. The quantitative control is convenient for adding liquid nitrogen and saving liquid nitrogen, and the convenience of operation is improved. The annular cooling box 2201, the retaining ring 2202, the extrusion ring 2204, the cooling screw 2205, the top cover box 2206, the shielding ring 2209, the right-angle stop 2210, the limit stop 2211 and the toggle rod 2212 are all made of glass fiber reinforced plastics.

[0050] When the amount to be ground is large or there are many types, the samples are quantitatively distributed and placed in each mortar 1 in turn, and the grinding head 2101, grinding head 2101, grinding ball 2104 and end cover 2106 are placed in turn, and the mortar 1 is placed in turn in the feeding guide rail 208 on one side, and the limit groove 4 is embedded in the limit guide rail 6, the iron strip 5 adsorbs the magnetic strip 7 for temporary limit, and the outer side of the annular cooling box 2201 is connected to the heat insulation sleeve 216, and the heat insulation sleeve 216 is close to the cooling box 2201. The fixed half ring 214 is put in, and the fixed half ring 214 and the movable half ring 217 are combined into a circle. The suction cup 215 is pressed, and the suction cup 215 absorbs the insulation sleeve 216 on one side to fix the insulation sleeve 216, and pushes the mortar 1 at the end, and the mortars 1 arranged in sequence slide along the feeding guide rail 208 until the mortar 1 at the end enters the embedded groove 209, and the feeding motor 213 is started, and the feeding motor 213 drives the feeding screw 212 to rotate, and pulls the feeding plate 211 to drive the embedded groove 209 The mortar 1 in the container moves up and is gradually embedded in the annular cooling box 2201. During this process, the top of the mortar rod 201 will be connected and assembled with the bottom of the grinding motor 202, and the grinding motor 202 and the horizontal connecting rod 203 will be lifted up, and the pulling rod 204 will rise along the guide tube 205. If cooling and grinding are required, the liquid nitrogen is added in the same way as the above-mentioned liquid nitrogen addition. The grinding motor 202 is started to drive the mortar rod 201 to rotate and grind. After the grinding is completed, the feeding motor 213 drives the feeding screw 212 to rotate in the opposite direction, and the feeding plate 211 moves down. Under the action of gravity, the feeding motor 213 will also push the mortar rod 201 and the mortar 1 out of the annular cooling box 2201 until the mortar rod 201 returns to the embedding groove 209, and continue to push the mortar 1 at the end, and push another mortar 1 to the top surface of the feeding plate 211, and repeat the above steps for grinding. The grinding is continuously performed in a semi-automatic manner, which is convenient for the sample processing of large quantities or a large number of types, and effectively improves the experimental efficiency.

[0051] Different structures and processing methods can be used according to the needs, when the amount to be ground is small, whether liquid nitrogen cooling is required, and the amount of experimental samples is large, or there are many types. When the amount is small, fewer structures are used and it is easy to carry and move. When the amount is large, semi-automatic continuous grinding is easy to operate and has high grinding efficiency. It is suitable for a variety of different experiments and experimental occasions and has a wider range of applications.

[0052] The grinding auxiliary component 21 relies on the collision of the grinding balls 2104 to improve the grinding effect while reducing adhesion. The quantitative cooling component 22 facilitates the quantitative addition of liquid nitrogen while reducing the consumption of liquid nitrogen and saving materials. It can be coordinated with the switching grinding component 2 under different experimental needs to achieve better and more efficient grinding results.

[0053] Finally, it should be noted that the above description is only a preferred example of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A molecular biology experimental sample grinder, comprising a mortar (1), characterized in that: A switchable grinding assembly (2) is arranged on the outside of the mortar (1), and the switchable grinding assembly (2) comprises a mortar rod (201); A mortar rod (201) is placed inside the mortar (1), the top end of the mortar rod (201) is movably connected to the output shaft end of the grinding motor (202), the top end of the grinding motor (202) is connected to one end of the bottom surface of the horizontal connecting rod (203), the other end of the bottom surface of the horizontal connecting rod (203) is connected to a pull rod (204), the bottom end of the pull rod (204) is movably sleeved with a guide tube (205), the bottom end of the guide tube (205) is fixedly connected to the bottom surface of a support seat (206), the support seat (206) is provided with a feeding hole (207) at the bottom end of the mortar (1), and both ends of the feeding hole (207) are installed with feeding guide rails (208), the An embedding groove (209) is provided at the bottom end of the feeding hole (207), a lifting hole (210) is provided at the middle part of the inner side of the feeding hole (207), a feeding plate (211) is movably embedded and installed inside the embedding groove (209), one end of the feeding plate (211) passes through the lifting hole (210) and is connected to a feeding screw rod (212) through a screw hole, the top end of the feeding screw rod (212) is connected to the output shaft of a feeding motor (213), the feeding motor (213) is installed on one side of a fixed half ring (214), the fixed half ring (214) is fixedly installed on one side of the top end of the feeding hole (207), and a suction cup (215) is installed through one side of the fixed half ring (214); A grinding auxiliary component (21) is installed inside the mortar (1), a quantitative cooling component (22) is sleeved on the outside of the mortar (1), a heat insulating sleeve (216) is sleeved on the outside of the quantitative cooling component (22), a movable half ring (217) is fixedly installed on one side of the heat insulating sleeve (216), a switching tube (218) is fixedly installed in the middle of one side of the movable half ring (217), a switching rod (219) is movably installed inside the switching tube (218), the top end of the switching rod (219) is fixedly connected to one end of a steering plate (220), the other end of the steering plate (220) is movably installed with a clamping tube (221), and a rotating handle (222) is welded to the top end of the clamping tube (221).

2. A molecular biology experimental sample grinder according to claim 1, characterized in that: The grinding auxiliary component (21) comprises a grinding head (2101); The bottom end of the mortar rod (201) is fixedly connected to a grinding head (2101); an upper baffle (2102) is symmetrically fixedly installed on the top of the grinding head (2101); a lower baffle (2103) is symmetrically fixedly installed in the middle of the grinding head (2101); a grinding ball (2104) is placed inside the mortar (1); a support spring (2105) is sleeved in the middle of the mortar rod (201); an end cover (2106) is movably sleeved on the top of the mortar rod (201); a retaining edge (2107) is welded to the edge of the end cover (2106); and filling holes (2108) are evenly opened on the top surface of the retaining edge (2107).

3. A molecular biology experimental sample grinder according to claim 2, characterized in that: The quantitative cooling component (22) comprises an annular cooling box (2201); The outer side of the mortar (1) is sleeved with an annular cooling box (2201), a retaining ring (2202) is fixedly installed inside the annular cooling box (2201), the bottom end of the retaining ring (2202) is symmetrically provided with extrusion holes (2203), the top end of the retaining ring (2202) is movably sleeved with an extrusion ring (2204), one side of the extrusion ring (2204) is installed with a cooling screw (2205) through a screw hole, the top end of the annular cooling box (2201) is abutted against a top cover box (2206), the top end of the cooling screw (2205) rotates through the top cover box (2206) ) is connected with a knob (2207), the bottom surface of the top cover box (2206) is aligned with the retaining edge (2107) and is provided with an injection hole (2208), the inner edge of the top end of the top cover box (2206) is rotatably inlaid with a blocking ring (2209), the bottom end of the blocking ring (2209) is fixedly installed with a right-angle block (2210) corresponding to the injection hole (2208), the top cover box (2206) is provided with a limit block (2211) near the injection hole (2208), and a toggle rod (2212) is fixedly installed on one side of the top surface of the blocking ring (2209).

4. A molecular biology experimental sample grinder according to claim 2, characterized in that: The inner bottom end of the mortar (1) is rounded, the cross section of the retaining edge (2107) is a right angle, and the retaining edge (2107) and the top end of the mortar (1) are connected in a transition fit manner.

5. The molecular biology experimental sample grinder according to claim 2, characterized in that: The distance between the upper baffle plate (2102) and the lower baffle plate (2103) is smaller than the diameter of the grinding ball (2104); the ends and edges of the upper baffle plate (2102) and the lower baffle plate (2103) are rounded; and the spatial angle between the upper baffle plate (2102) and the lower baffle plate (2103) is 90°.

6. The molecular biology experimental sample grinder according to claim 2, characterized in that: A motor tray (3) is mounted on one side of the fixed half ring (214), the feeding motor (213) is mounted on the top surface of the motor tray (3), and the output shaft of the feeding motor (213) movably passes through the motor tray (3).

7. The molecular biology experimental sample grinder according to claim 3, characterized in that: The top cover box (2206) has a hollow right angle opening at the bottom end of the cross section, the top end of the retaining ring (2202) contacts the inner top surface of the top cover box (2206), the outer side of the extrusion ring (2204) fits the inner wall of the annular cooling box (2201) close to the outer side, and the inner side of the extrusion ring (2204) fits the outer side of the retaining ring (2202).

8. The molecular biology experimental sample grinder according to claim 3, characterized in that: A limiting groove (4) is provided at the bottom end of the mortar (1), an iron strip (5) is embedded at the top end of the limiting groove (4), a limiting guide rail (6) is fixedly installed in the middle of the top surface of the feeding guide rail (208) and the feeding plate (211), and a magnetic strip (7) is bonded to the top surface of the limiting guide rail (6).

9. The molecular biology experimental sample grinder according to claim 1, characterized in that: The input ends of the grinding motor (202) and the feeding motor (213) are electrically connected to the output end of an external power supply respectively. The diameter of the mortar (1) is equal to the diameter of the embedding groove (209), and the top edge of the embedding groove (209) is chamfered.

10. The molecular biology experimental sample grinder according to claim 1, characterized in that: The pulling rod (204) is a hexagonal prism, the conduit (205) is a circular tube with a regular hexagonal hole in the middle, and the fixed half ring (214) and the movable half ring (217) are spliced ​​into a circular ring shape.

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