Application of hydroxytyrosol in growth performance of meat geese

Abstract

The invention discloses an application of hydroxytyrosol in growth performance of meat geese, which is characterized in that hydroxytyrosol is microencapsulated to prepare a synergistic regulator, and the synergistic regulator is added into a meat goose feed; the synergistic regulator is prepared from the following raw materials: hydroxytyrosol, an auxiliary agent a, an auxiliary agent b, an auxiliary agent c and a wall material. The feed can significantly improve the growth performance of meat geese, reduce the feed conversion ratio, reduce the breeding cost and improve the economic benefits.

Description

Technical Field

[0001] The invention belongs to the technical field of breeding, and in particular relates to application of hydroxytyrosol in the growth performance of meat geese. Background Art

[0002] Hydroxytyrosol is a natural phenolic compound. Its chemical name is 3,4-dihydroxyphenylethanol and its molecular formula is C8H 10 O3, its structure contains a benzene ring, with hydroxyl groups (-OH) connected to the 3rd and 4th positions of the benzene ring, and an ethanol (-CHCHOH) side chain structure. Hydroxytyrosol mainly comes from olives (Oleaeuropaea). It is abundant in olive fruits and olive oil. When olives are processed into olive oil, hydroxytyrosol is extracted along with other ingredients in the olives. It is one of the most important bioactive ingredients in olive oil.

[0003] Hydroxytyrosol has antioxidant, cardiovascular protection, and neuroprotective effects. Hydroxytyrosol is widely used in food, medicine, agriculture, and aquaculture. In aquaculture, adding hydroxytyrosol to animal feed can improve the health of animals. For poultry and livestock, it can enhance the immunity of animals and reduce the occurrence of diseases. For example, adding hydroxytyrosol to broiler feed can improve the antioxidant capacity of chickens, reduce the decline in meat quality caused by oxidative stress, and help the growth of chickens, making the quality of chicken better, such as brighter color and more tender taste. At the same time, in aquaculture, hydroxytyrosol can also be used in feed for fish and shrimp to improve the stress resistance of aquatic animals and promote their growth and reproduction.

[0004] Hydroxytyrosol plays many roles in goose farming. In terms of goose growth performance, hydroxytyrosol can promote goose growth. Since goose growth requires a lot of nutrients and energy, and has a fast metabolism, this will lead to more free radicals in the body. The antioxidant properties of hydroxytyrosol can remove these free radicals and reduce the inhibitory effect of oxidative stress on goose growth. By reducing oxidative stress, it helps maintain the normal metabolism and physiological function of goose cells, so that goose can more effectively utilize the nutrients in the feed and achieve faster growth.

[0005] At the same time, hydroxytyrosol can improve the feed conversion rate of meat geese and protect the nutrients in the feed, such as preventing the oxidative decomposition of fat, protein and vitamins. At the same time, it plays an antioxidant and physiological function regulating role in the meat goose, so that the meat goose can better absorb and utilize the nutrients in the feed, reduce feed waste, and improve the efficiency of converting feed into weight gain of meat geese.

[0006] In terms of meat quality, the fat content in goose meat is relatively high, and it is easy to oxidize during storage and processing, producing unpleasant odors. Hydroxytyrosol can prevent fat oxidation and reduce the generation of odors. At the same time, it helps to maintain the stability of pigments such as myoglobin in goose meat, making the color of goose meat more vivid. At the same time, from a nutritional point of view, hydroxytyrosol itself has certain health functions, such as anti-oxidation and anti-inflammatory. When goose meat ingests feed containing hydroxytyrosol, these beneficial ingredients may accumulate to a certain extent in goose meat, or improve its nutritional value by changing the nutritional composition of goose meat.

[0007] In terms of immunity and disease resistance, meat geese are vulnerable to various pathogens such as viruses, bacteria and parasites during the breeding process. Hydroxytyrosol can regulate the immune system of meat geese and enhance the activity of immune cells. For example, it may stimulate the proliferation of lymphocytes in meat geese, increase antibody levels, and enhance the nonspecific and specific immune functions of meat geese. By enhancing immunity, meat geese can better resist diseases, reduce the frequency of diseases, and reduce mortality during breeding. At the same time, meat geese face a variety of stress factors in the breeding environment, such as temperature changes, stocking density, water quality, etc. The antioxidant and physiological regulation effects of hydroxytyrosol help meat geese better cope with these stresses. It can reduce oxidative damage and physiological dysfunction caused by stress and maintain the physiological balance of meat geese. For example, in a high temperature environment, meat geese are prone to heat stress. Hydroxytyrosol can alleviate the adverse effects of heat stress on meat geese and improve the survival ability and production performance of meat geese.

[0008] However, in the prior art, hydroxytyrosol is usually directly added to feed ingredients, which cannot maximize the efficacy of hydroxytyrosol and has insufficient utilization, resulting in insufficient effect of hydroxytyrosol on improving the growth performance of meat geese. Summary of the invention

[0009] The purpose of the present invention is to provide application of hydroxytyrosol in the growth performance of meat geese, so as to solve the technical problems in the above-mentioned prior art.

[0010] In order to achieve the above object, the present invention adopts the following technical solutions:

[0011] Application of hydroxytyrosol in the growth performance of goose: hydroxytyrosol is microencapsulated and prepared into a synergistic regulator, which is added to goose feed;

[0012] The synergistic regulator is made of the following raw materials: hydroxytyrosol, auxiliary agent a, auxiliary agent b, auxiliary agent c and wall material.

[0013] Furthermore, the synergistic regulator comprises the following raw materials in parts by weight: 10-30 parts of hydroxytyrosol, 5-10 parts of auxiliary agent a, 10-20 parts of auxiliary agent b, 8-18 parts of auxiliary agent c, and 20-40 parts of wall material.

[0014] Furthermore, the auxiliary agent a is curcumin; the auxiliary agent b is taurine; and the auxiliary agent c is glutathione.

[0015] Furthermore, the wall material is gelatin or gum arabic.

[0016] Furthermore, the preparation method of the synergistic regulator comprises the following steps:

[0017] S1 core material preparation: hydroxytyrosol, curcumin, taurine and glutathione are prepared into core material solution;

[0018] S2 wall material preparation: place the soaked wall material in a water bath, heat it in a water bath at 50-60°C to dissolve it, and obtain a wall material solution;

[0019] S3 mixing: slowly add the core material solution to the wall material solution, stir and react for 5-10 minutes to obtain a mixed solution;

[0020] S4 emulsification: pour the mixed solution into the container of the emulsifier, emulsify at a temperature of 40-60°C and a speed of 4000-8000 r / min for 10-30 minutes to form an emulsion;

[0021] S5 microcapsule solidification molding: adjust the pH of the emulsion while stirring, and cool it after adjustment to solidify the capsule;

[0022] S6 post-treatment: Use a filter to separate the solidified microcapsules from the emulsion, wash the microcapsules with deionized water for multiple times, and the amount of water used for each washing is 3-5 times the volume of the microcapsules; transfer the washed microcapsules to a vacuum drying oven, dry them at a vacuum degree of 0.08-0.1MPa and a temperature of 40-60°C for 12-24h to obtain a synergistic regulator.

[0023] Furthermore, in S1, the preparation method of the core material is: hydroxytyrosol and curcumin are put into a container, an ethanol-water solution is added, and the mixture is stirred at a speed of 300-500 r / min for 30-60 min at room temperature; in another container, taurine and glutathione are added into deionized water, and the mixture is stirred at a speed of 400-600 r / min for 20-40 min at room temperature; the aqueous solution of taurine and glutathione is slowly added into the mixed solution of hydroxytyrosol and curcumin, while stirring, and stirring is continued for 10-20 minutes after the addition is completed, to obtain a core material solution.

[0024] Furthermore, in the ethanol-water solution, ethanol:water is prepared in a volume ratio of 1:1-3.

[0025] Furthermore, in S5, the curing method is: slowly adding acetic acid solution to the emulsion under stirring to adjust the pH to 4.0-4.5; quickly transferring the emulsion with adjusted pH to an ice bath for cooling, and maintaining stirring for 30-60 minutes to solidify the microcapsules.

[0026] Furthermore, the meat goose feed is made from the following raw materials: corn, wheat, protein, minerals, vitamins, and synergistic regulators.

[0027] Furthermore, the preparation method of the meat goose feed is: putting the synergistic regulator, corn and wheat bran into a blender, stirring and mixing for 5-10 minutes; then putting the mixed synergistic regulator, corn and wheat bran mixture into the mixer together, stirring and mixing for 10-15 minutes, to obtain the meat goose feed.

[0028] Compared with the prior art, the present invention has the following beneficial effects:

[0029] 1. The present invention prepares a synergistic regulator from hydroxytyrosol and adds the synergistic regulator to goose feed, thereby significantly improving the growth performance of goose, reducing feed-to-meat ratio, reducing breeding costs, and improving economic benefits.

[0030] 2. In the synergistic regulator adopted by the present invention, curcumin, taurine and sodium glutcysteine ​​can work together to synergistically enhance the effect of hydroxytyrosol in meat goose feed.

[0031] 3. The present invention microencapsulates the synergistic regulator to enable sustained release of the synergistic regulator, so that its components continue to exert synergistic effects over a long period of time, thereby improving the effect on the growth performance of meat geese.

[0032] 4. The present invention premixes the synergistic regulator with corn and wheat bran, so that the synergistic regulator can be better attached to the surface thereof, and with the help of the dispersion effect of corn and wheat bran in the subsequent mixing process, the synergistic regulator is more evenly distributed in the entire feed system, thereby improving fluidity and operability. DETAILED DESCRIPTION

[0033] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, preferred embodiments are given below to further describe the present invention in detail. However, it should be noted that many details listed in the specification are only for the purpose of enabling the reader to have a thorough understanding of one or more aspects of the present invention, and these aspects of the present invention can be implemented even without these specific details.

[0034] An application of hydroxytyrosol in the growth performance of meat geese, specifically comprising: preparing hydroxytyrosol into a synergistic regulator after microencapsulation, and adding the hydroxytyrosol into meat goose feed;

[0035] The synergistic regulator comprises the following raw materials in parts by weight: 10-30 parts of hydroxytyrosol, 5-10 parts of auxiliary agent a curcumin, 10-20 parts of auxiliary agent b taurine, 8-18 parts of auxiliary agent c glutathione and 20-40 parts of wall material.

[0036] The wall material is gelatin or gum arabic.

[0037] The preparation method of the synergistic regulator comprises the following steps:

[0038] S1 core material preparation: hydroxytyrosol and curcumin are placed in a container, and an ethanol-water solution prepared by ethanol: water in a volume ratio of 1:1-3 is added, and stirred at a speed of 300-500r / min for 30-60min at room temperature; in another container, taurine and glutathione are added to deionized water, and stirred at a speed of 400-600r / min for 20-40min at room temperature; the aqueous solution of taurine and glutathione is slowly added to the mixed solution of hydroxytyrosol and curcumin, while stirring, and stirring is continued for 10-20 minutes after the addition is completed to obtain a core material solution;

[0039] S2 wall material preparation: place the soaked wall material in a water bath, heat it in a water bath at 50-60°C to dissolve it, and obtain a wall material solution;

[0040] S3 mixing: slowly add the core material solution to the wall material solution, stir and react for 5-10 minutes to obtain a mixed solution;

[0041] S4 emulsification: pour the mixed solution into the container of the emulsifier, emulsify at a temperature of 40-60°C and a speed of 4000-8000 r / min for 10-30 minutes to form an emulsion;

[0042] S5 microcapsule solidification molding: slowly add acetic acid solution to the emulsion under stirring to adjust the pH to 4.0-4.5; quickly transfer the emulsion with adjusted pH value to an ice bath for cooling and keep stirring for 30-60 minutes to solidify the microcapsules;

[0043] S6 post-treatment: Use a filter to separate the solidified microcapsules from the emulsion, wash the microcapsules with deionized water for multiple times, and the amount of water used for each washing is 3-5 times the volume of the microcapsules; transfer the washed microcapsules to a vacuum drying oven, dry them at a vacuum degree of 0.08-0.1MPa and a temperature of 40-60°C for 12-24h to obtain a synergistic regulator.

[0044] The meat goose feed is made from the following raw materials: 50-70 parts of corn, 10-20 parts of wheat bran, 15-25 parts of protein, 1-5 parts of minerals, 0.1-0.3 parts of vitamins, and 2-8 parts of synergistic regulators.

[0045] The preparation method of the meat goose feed is as follows: putting the synergistic regulator, corn and wheat bran into a mixer, stirring and mixing for 5-10 minutes; then putting the mixed synergistic regulator, corn and wheat bran mixture together with protein, minerals and vitamins into the mixer, stirring and mixing for 10-15 minutes to obtain the meat goose feed.

[0046] Corn and wheat bran are the main ingredients in goose feed, and have a large specific surface area and good adsorption. When the synergistic regulator is premixed with corn and wheat bran, it can better adhere to their surface, and with the help of the dispersion effect of corn and wheat bran in the subsequent mixing process, the synergistic regulator is more evenly distributed in the entire feed system. And the premix formed after the synergistic regulator is premixed with corn and wheat bran will have improved fluidity and operability. Compared with direct blending, the premix is ​​easier to operate when blended with other ingredients, and can be mixed with other ingredients more quickly and more fully, reducing mixing time and mixing energy consumption, and improving production efficiency. And good fluidity and operability help to ensure the uniform distribution of the premix in the entire feed, avoiding the unstable effect of the synergistic regulator due to uneven mixing or excessive or insufficient intake of some meat geese, thereby improving the overall effect of the synergistic regulator in meat goose feed.

[0047] The following is a more specific example.

[0048] Example 1

[0049] Application of hydroxytyrosol in the growth performance of goose: hydroxytyrosol is microencapsulated and prepared into a synergistic regulator, which is added to goose feed;

[0050] The synergistic regulator comprises the following raw materials in parts by weight: 27 parts of hydroxytyrosol, 6 parts of curcumin, 20 parts of taurine, 8 parts of glutathione and 34 parts of gelatin wall material.

[0051] The preparation method of the synergistic regulator comprises the following steps:

[0052] Preparation of S1 core material: Hydroxytyrosol and curcumin were placed in a container, and an ethanol-water solution prepared by ethanol: water in a volume ratio of 1:3 was added, and stirred at room temperature at a speed of 450r / min for 60min; in another container, taurine and glutathione were added to deionized water, and stirred at room temperature at a speed of 500r / min for 40min; the aqueous solution of taurine and glutathione was slowly added to the mixed solution of hydroxytyrosol and curcumin, while stirring, and continued to stir for 10 minutes after the addition was completed to obtain the core material solution;

[0053] S2 wall material preparation: place the soaked wall material in a water bath, heat it in a water bath at 52°C to dissolve it, and obtain a wall material solution;

[0054] S3 mixing: slowly add the core material solution to the wall material solution, stir and react for 10 minutes to obtain a mixed solution;

[0055] S4 emulsification: pour the mixed solution into the container of the emulsifier, emulsify at a temperature of 43°C and a speed of 6000r / min for 20min to form an emulsion;

[0056] S5 microcapsule solidification molding: under stirring, slowly add acetic acid solution to the emulsion to adjust the pH to 4.0; the emulsion with adjusted pH value is quickly transferred to an ice bath for cooling, and kept stirring for 55 minutes to solidify the microcapsules;

[0057] S6 post-treatment: Use a filter to separate the solidified microcapsules from the emulsion, wash the microcapsules with deionized water for multiple times, and the amount of water used for each wash is 3 times the volume of the microcapsules; transfer the washed microcapsules to a vacuum drying oven, dry them at a vacuum degree of 0.1 MPa and a temperature of 40°C for 17 hours to obtain a synergistic regulator.

[0058] The meat goose feed is made from the following raw materials: corn, wheat, protein, minerals, vitamins and synergistic regulators.

[0059] The preparation method of the meat goose feed is as follows: putting the synergistic regulator, corn and wheat bran into a mixer, stirring and mixing for 10 minutes; then putting the mixed synergistic regulator, corn and wheat bran mixture into the mixer together, stirring and mixing for 15 minutes, and obtaining the meat goose feed.

[0060] Example 2

[0061] Application of hydroxytyrosol in the growth performance of goose: hydroxytyrosol is microencapsulated and prepared into a synergistic regulator, which is added to goose feed;

[0062] The synergistic regulator is made of the following raw materials in parts by weight: 10 parts of hydroxytyrosol, 5 parts of curcumin, 14 parts of taurine, 12 parts of glutathione and 27 parts of arabic gum wall material.

[0063] The preparation method of the synergistic regulator comprises the following steps:

[0064] Preparation of S1 core material: Hydroxytyrosol and curcumin were placed in a container, and an ethanol-water solution prepared by ethanol: water in a volume ratio of 1:2 was added, and stirred at room temperature at a speed of 500 r / min for 50 minutes; in another container, taurine and glutathione were added to deionized water, and stirred at room temperature at a speed of 400 r / min for 20 minutes; the aqueous solution of taurine and glutathione was slowly added to the mixed solution of hydroxytyrosol and curcumin, while stirring, and continued to stir for 15 minutes after the addition was completed to obtain the core material solution;

[0065] S2 wall material preparation: place the soaked wall material in a water bath, heat it in a water bath at 50°C to dissolve it, and obtain a wall material solution;

[0066] S3 mixing: slowly add the core material solution into the wall material solution, stir and react for 6 minutes to obtain a mixed solution;

[0067] S4 emulsification: pour the mixed solution into the container of the emulsifier, emulsify at a temperature of 48°C and a speed of 8000r / min for 15min to form an emulsion;

[0068] S5 microcapsule solidification molding: slowly add acetic acid solution to the emulsion under stirring to adjust the pH to 4.5; quickly transfer the emulsion with adjusted pH to an ice bath for cooling and keep stirring for 60 minutes to solidify the microcapsules;

[0069] S6 post-treatment: Use a filter to separate the solidified microcapsules from the emulsion, wash the microcapsules with deionized water for multiple times, and the amount of water used for each wash is 3.4 times the volume of the microcapsules; transfer the washed microcapsules to a vacuum drying oven, dry them at a vacuum degree of 0.09 MPa and a temperature of 54°C for 24 hours to obtain a synergistic regulator.

[0070] The meat goose feed is made from the following raw materials: corn, wheat, protein, minerals, vitamins and synergistic regulators.

[0071] The preparation method of the meat goose feed is as follows: putting the synergistic regulator, corn and wheat bran into a mixer, stirring and mixing for 5 minutes; then putting the mixed synergistic regulator, corn and wheat bran mixture into the mixer together, stirring and mixing for 15 minutes, and obtaining the meat goose feed.

[0072] Example 3

[0073] Application of hydroxytyrosol in the growth performance of goose: hydroxytyrosol is microencapsulated and prepared into a synergistic regulator, which is added to goose feed;

[0074] The synergistic regulator is made of the following raw materials in parts by weight: 18 parts of hydroxytyrosol, 10 parts of curcumin, 18 parts of taurine, 15 parts of glutathione, and 22 parts of gum arabic wall material.

[0075] The preparation method of the synergistic regulator comprises the following steps:

[0076] Preparation of S1 core material: Hydroxytyrosol and curcumin were placed in a container, and an ethanol-water solution prepared by ethanol: water in a volume ratio of 1:2 was added, and stirred at room temperature at a speed of 300 r / min for 40 minutes; in another container, taurine and glutathione were added to deionized water, and stirred at room temperature at a speed of 600 r / min for 30 minutes; the aqueous solution of taurine and glutathione was slowly added to the mixed solution of hydroxytyrosol and curcumin, while stirring, and continued to stir for 20 minutes after the addition was completed to obtain the core material solution;

[0077] S2 wall material preparation: place the soaked wall material in a water bath, heat it in a water bath at 58°C to dissolve it, and obtain a wall material solution;

[0078] S3 mixing: slowly add the core material solution to the wall material solution, stir and react for 5 minutes to obtain a mixed solution;

[0079] S4 emulsification: pour the mixed solution into the container of the emulsifier, emulsify at a temperature of 60°C and a speed of 4000r / min for 10min to form an emulsion;

[0080] S5 microcapsule solidification molding: under stirring, slowly add acetic acid solution to the emulsion to adjust the pH to 4.5; the emulsion with adjusted pH value is quickly transferred to an ice bath for cooling, and kept stirring for 30 minutes to solidify the microcapsules;

[0081] S6 post-treatment: Use a filter to separate the solidified microcapsules from the emulsion, wash the microcapsules with deionized water for multiple times, and the amount of water used for each washing is 4.8 times the volume of the microcapsules; transfer the washed microcapsules to a vacuum drying oven, dry them at a vacuum degree of 0.08 MPa and a temperature of 42°C for 15 hours to obtain a synergistic regulator.

[0082] The meat goose feed is made from the following raw materials: corn, wheat, protein, minerals, vitamins and synergistic regulators.

[0083] The preparation method of the meat goose feed is as follows: putting the synergistic regulator, corn and wheat bran into a mixer, stirring and mixing for 8 minutes; then putting the mixed synergistic regulator, corn and wheat bran mixture into the mixer together, stirring and mixing for 10 minutes, and obtaining the meat goose feed.

[0084] Example 4

[0085] Application of hydroxytyrosol in the growth performance of goose: hydroxytyrosol is microencapsulated and prepared into a synergistic regulator, which is added to goose feed;

[0086] The synergistic regulator comprises the following raw materials in parts by weight: 25 parts of hydroxytyrosol, 9 parts of curcumin, 10 parts of taurine, 18 parts of glutathione and 40 parts of gelatin.

[0087] The preparation method of the synergistic regulator comprises the following steps:

[0088] Preparation of S1 core material: Hydroxytyrosol and curcumin were placed in a container, and an ethanol-water solution prepared by ethanol: water in a volume ratio of 1:1 was added, and stirred at room temperature at a speed of 450r / min for 60min; in another container, taurine and glutathione were added to deionized water, and stirred at room temperature at a speed of 550r / min for 40min; the aqueous solution of taurine and glutathione was slowly added to the mixed solution of hydroxytyrosol and curcumin, while stirring, and continued to stir for 12 minutes after the addition was completed to obtain the core material solution;

[0089] S2 wall material preparation: place the soaked wall material in a water bath, heat it in a water bath at 54°C to dissolve it, and obtain a wall material solution;

[0090] S3 mixing: slowly add the core material solution into the wall material solution, stir and react for 8 minutes to obtain a mixed solution;

[0091] S4 emulsification: pour the mixed solution into the container of the emulsifier, emulsify at a temperature of 55°C and a speed of 5000r / min for 30min to form an emulsion;

[0092] S5 microcapsule solidification molding: under stirring, slowly add acetic acid solution to the emulsion to adjust the pH to 4.5; the emulsion with adjusted pH value is quickly transferred to an ice bath for cooling, and kept stirring for 35 minutes to solidify the microcapsules;

[0093] S6 post-treatment: Use a filter to separate the solidified microcapsules from the emulsion, wash the microcapsules with deionized water for multiple times, and the amount of water used for each washing is 5 times the volume of the microcapsules; transfer the washed microcapsules to a vacuum drying oven, dry them at a vacuum degree of 0.08 MPa and a temperature of 60°C for 20 hours to obtain a synergistic regulator.

[0094] The meat goose feed is made from the following raw materials: corn, wheat, protein, minerals, vitamins and synergistic regulators.

[0095] The preparation method of the meat goose feed is as follows: putting the synergistic regulator, corn and wheat bran into a mixer, stirring and mixing for 6 minutes; then putting the mixed synergistic regulator, corn and wheat bran mixture into the mixer together, stirring and mixing for 11 minutes, and obtaining the meat goose feed.

[0096] Example 5

[0097] Application of hydroxytyrosol in the growth performance of goose: hydroxytyrosol is microencapsulated and prepared into a synergistic regulator, which is added to goose feed;

[0098] The synergistic regulator comprises the following raw materials in parts by weight: 30 parts of hydroxytyrosol, 7 parts of curcumin, 16 parts of taurine, 10 parts of glutathione and 200 parts of gum arabic.

[0099] The preparation method of the synergistic regulator comprises the following steps:

[0100] Preparation of S1 core material: Hydroxytyrosol and curcumin were placed in a container, and an ethanol-water solution prepared by ethanol: water in a volume ratio of 1:3 was added, and stirred at 350 r / min for 30 min at room temperature; in another container, taurine and glutathione were added to deionized water, and stirred at 450 r / min for 20 min at room temperature; the aqueous solution of taurine and glutathione was slowly added to the mixed solution of hydroxytyrosol and curcumin, while stirring, and continued to stir for 18 minutes after the addition was completed to obtain the core material solution;

[0101] S2 wall material preparation: place the soaked wall material in a water bath, heat it in a water bath at 60°C to dissolve it, and obtain a wall material solution;

[0102] S3 mixing: slowly add the core material solution to the wall material solution, stir and react for 5 minutes to obtain a mixed solution;

[0103] S4 emulsification: pour the mixed solution into the container of the emulsifier, emulsify at a temperature of 40°C and a speed of 7000r / min for 25min to form an emulsion;

[0104] S5 microcapsule solidification molding: under stirring, slowly add acetic acid solution to the emulsion to adjust the pH to 4.0; the emulsion with adjusted pH value is quickly transferred to an ice bath for cooling, and kept stirring for 45 minutes to solidify the microcapsules;

[0105] S6 post-treatment: Use a filter to separate the solidified microcapsules from the emulsion, wash the microcapsules with deionized water for multiple times, and the amount of water used for each wash is 4.2 times the volume of the microcapsules; transfer the washed microcapsules to a vacuum drying oven, dry them at a vacuum degree of 0.1 MPa and a temperature of 55°C for 12 hours to obtain a synergistic regulator.

[0106] The meat goose feed is made from the following raw materials: corn, wheat, protein, minerals, vitamins and synergistic regulators.

[0107] The preparation method of the meat goose feed is as follows: putting the synergistic regulator, corn and wheat bran into a mixer, stirring and mixing for 8 minutes; then putting the mixed synergistic regulator, corn and wheat bran mixture into the mixer together, stirring and mixing for 13 minutes, and obtaining the meat goose feed.

[0108] Comparative Example 1

[0109] The method is basically the same as Example 1, except that curcumin, taurine and glutathione are not added to the synergistic regulator.

[0110] Comparative Example 2

[0111] The method is basically the same as Example 1, except that taurine and glutathione are not added to the synergistic regulator.

[0112] Comparative Example 3

[0113] The method is basically the same as Example 1, except that curcumin and glutathione are not added to the synergistic regulator.

[0114] Comparative Example 4

[0115] The method is basically the same as Example 1, except that taurine and glutathione are not added to the synergistic regulator.

[0116] Comparative Example 5

[0117] The same as Example 1, except that no wall material was added to the synergistic regulator for microencapsulation

[0118] 1. Meat goose breeding experiment

[0119] 60 healthy, 4-week-old Guangxi Hepu grey geese of similar weight were selected and divided into 10 groups, each with 30 geese, and the geese were fed with the goose feeds of Examples 1-5 and Comparative Examples 1-5 for 70 days. The average daily weight gain and feed-to-meat ratio of the geese were calculated.

[0120]

[0121]

[0122] It can be seen from Table 1 that:

[0123] (1) In Examples 1-5 of the present invention, the average daily weight gain of the geese was 72.2 g, 71.4 g, 70.8 g, 68.7 g, and 69.6 g, respectively, and the feed-to-meat ratio was 3.07, 3.14, 3.21, 3.30, and 3.37, respectively. Among them, the average daily weight gain of the geese in Example 1 reached 72.2 g, and the feed-to-meat ratio reached 3.07, while in Comparative Examples 1-4 where the adjuvant in the synergistic regulator of the present application was not used or the adjuvant in the present application was not fully used, the geese The average daily weight gain was 55.7g, 63.0g, 60.3g and 58.5g respectively, and the feed-to-meat ratio was 4.25, 4.03, 4.11 and 3.97 respectively, which were all inferior to Examples 1-5 of the present application, indicating that in the synergistic regulator of the present application, curcumin, taurine and glutathione can interact with each other, synergistically enhance the effect of hydroxytyrosol in meat goose feed, thereby significantly improving the growth performance of meat geese, reducing the feed-to-meat ratio, reducing costs and improving breeding efficiency.

[0124] This is because: curcumin has a certain antioxidant capacity, which reduces the damage of oxidative stress to meat goose cells, and works together with hydroxytyrosol to enhance the antioxidant effect, providing a more favorable intracellular environment for the growth of meat geese, so that meat goose cells can metabolize and physiological activities more normally, thereby promoting the absorption and utilization of nutrients by meat geese, increasing weight gain rate and reducing feed-to-meat ratio. At the same time, curcumin can regulate various signal pathways in meat geese, affect cell proliferation, differentiation and metabolism, and work together with hydroxytyrosol to promote the growth and development of meat goose muscle cells, thereby increasing the weight gain rate of meat geese.

[0125] As a sulfur-containing amino acid, taurine has the functions of regulating osmotic pressure and stabilizing cell membranes. It also participates in the body's antioxidant defense system, can enhance the activity of antioxidant enzymes, and synergizes with hydroxytyrosol and curcumin to further remove free radicals, reduce oxidative stress, and reduce the waste of energy and nutrients caused by oxidative damage during the growth of meat geese, improve feed utilization, promote weight gain and reduce feed-to-meat ratio. At the same time, taurine can participate in the synthesis of bile acids, promote fat digestion and absorption, and synergize with hydroxytyrosol to enable meat geese to better utilize the fat components in feed, improve energy supply, promote growth, and reduce feed waste caused by fat indigestion and reduce feed-to-meat ratio.

[0126] Glutathione can work together with hydroxytyrosol and curcumin to maintain the redox balance in cells, protect cells from oxidative damage, ensure normal cell function and metabolism, help meat geese better digest and absorb nutrients in feed, improve the efficiency of converting feed into body weight, thereby increasing the weight gain rate of meat geese and reducing the feed-to-meat ratio.

[0127] Therefore, the combined use of curcumin, taurine and glutathione can synergistically improve the effect of hydroxytyrosol in meat goose feed, significantly improve the growth performance of meat geese, and reduce the feed-to-meat ratio.

[0128] (2) In comparative example 5, the synergistic regulator was not microencapsulated and added to goose feed. The average weight gain of the goose was 66.1 g, and the feed-to-meat ratio was 3.64, which was not as good as that of Examples 1-5 of the present application. This shows that the present application can improve the growth performance of goose and reduce the feed-to-meat ratio by adding the microencapsulated synergistic regulator to goose feed.

[0129] This is due to:

[0130] Microencapsulated synergistic regulators can control the slow release of hydroxytyrosol and adjuvants under specific conditions, prolonging their action time in the body or in the action environment. If hydroxytyrosol and adjuvants are released in large quantities at one time, they may be metabolized or excreted from the body in a short period of time and cannot fully exert their effects. However, slow release through microencapsulation can enable its ingredients to continue to exert synergistic effects for a longer period of time, thereby improving the effect on the growth performance of meat geese.

[0131] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. The application of hydroxytyrosol in the growth performance of meat geese is characterized by: The hydroxytyrosol is microencapsulated to prepare a synergistic regulator, which is added to goose feed; The synergistic regulator is made of the following raw materials: hydroxytyrosol, auxiliary agent a, auxiliary agent b, auxiliary agent c and wall material.

2. The application of hydroxytyrosol in the growth performance of meat geese according to claim 1, characterized in that: The synergistic regulator comprises the following raw materials in parts by weight: 10-30 parts of hydroxytyrosol, 5-10 parts of auxiliary agent a, 10-20 parts of auxiliary agent b, 8-18 parts of auxiliary agent c and 20-40 parts of wall material.

3. The application of hydroxytyrosol in the growth performance of meat geese according to claim 2, characterized in that: The auxiliary agent a is curcumin; the auxiliary agent b is taurine; and the auxiliary agent c is glutathione.

4. The use of hydroxytyrosol in the growth performance of meat geese according to claim 3, characterized in that: The wall material is gelatin or gum arabic.

5. The use of hydroxytyrosol in the growth performance of meat geese according to any one of claims 1 to 4, characterized in that: The preparation method of the synergistic regulator comprises the following steps: S1 core material preparation: hydroxytyrosol, curcumin, taurine and glutathione are prepared into core material solution; S2 wall material preparation: place the soaked wall material in a water bath, heat it in a water bath at 50-60°C to dissolve it, and obtain a wall material solution; S3 mixing: slowly add the core material solution to the wall material solution, stir and react for 5-10 minutes to obtain a mixed solution; S4 emulsification: pour the mixed solution into the container of the emulsifier, emulsify at a temperature of 40-60°C and a speed of 4000-8000 r / min for 10-30 minutes to form an emulsion; S5 microcapsule solidification molding: adjust the pH of the emulsion while stirring, and cool it after adjustment to solidify the capsule; S6 post-treatment: Use a filter to separate the solidified microcapsules from the emulsion, wash the microcapsules with deionized water for multiple times, and the amount of water used for each washing is 3-5 times the volume of the microcapsules; transfer the washed microcapsules to a vacuum drying oven, dry them at a vacuum degree of 0.08-0.1MPa and a temperature of 40-60°C for 12-24h to obtain a synergistic regulator.

6. The use of hydroxytyrosol in the growth performance of meat geese according to claim 5, characterized in that: In S1, the preparation method of the core material is: hydroxytyrosol and curcumin are put into a container, an ethanol-water solution is added, and the mixture is stirred at a speed of 300-500 r / min for 30-60 min at room temperature; in another container, taurine and glutathione are added into deionized water, and the mixture is stirred at a speed of 400-600 r / min for 20-40 min at room temperature; the aqueous solution of taurine and glutathione is slowly added into the mixed solution of hydroxytyrosol and curcumin, while stirring, and stirring is continued for 10-20 minutes after the addition is completed, to obtain a core material solution.

7. The use of hydroxytyrosol in the growth performance of meat geese according to claim 6, characterized in that: In the ethanol-water solution, ethanol:water is prepared in a volume ratio of 1:1-3.

8. The use of hydroxytyrosol in the growth performance of meat geese according to claim 5, characterized in that: In S5, the curing method is: slowly adding acetic acid solution to the emulsion under stirring to adjust the pH value to 4.0-4.5; quickly transferring the emulsion with adjusted pH value to an ice bath for cooling, and keeping stirring for 30-60 minutes to solidify the microcapsules.

9. The use of hydroxytyrosol in the growth performance of meat geese according to any one of claims 1 to 4, characterized in that: The meat goose feed is made from the following raw materials: corn, wheat, protein, minerals, vitamins and synergistic regulators.

10. The use of hydroxytyrosol in the growth performance of meat geese according to claim 9, characterized in that: The preparation method of the meat goose feed is as follows: putting the synergistic regulator, corn and wheat bran into a mixer, stirring and mixing for 5-10 minutes; then putting the mixed synergistic regulator, corn and wheat bran mixture together with other ingredients into a mixer, stirring and mixing for 10-15 minutes to obtain the meat goose feed.

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