Microwave energy-gathering thermal therapy device and system for tumor treatment

Abstract

The invention provides a microwave energy-gathering thermal therapy device and system for tumor treatment, and the system comprises a microwave transmitting module of which a transmitting port is used for transmitting microwaves to tumor tissues so as to heat the tumor tissues; the energy-gathering and wave-guiding module is arranged in front of the emission port and is used for gathering microwaves in a tumor area; the cooling module is arranged around the emission port so as to form a cooling channel on the periphery of the emission port; the information acquisition module is used for acquiring induction information and image information of the tumor tissue; the control module is in communication connection with the microwave emission module, the cooling module and the information acquisition module and is used for generating microwave frequency information, temperature adjustment information and a target area according to induction information and image information sent by the information acquisition module before the microwave emission module emits microwaves to the tumor tissue, and the target area is located in the tumor tissue and is used for adjusting the temperature of the tumor tissue. And controlling the microwave emission module to emit microwaves to the target area according to the microwave frequency information, and adjusting the power of the cooling module according to the temperature adjustment information.

Description

Technical Field

[0001] The present application relates to the technical field of radiotherapy using microwaves, and in particular to a microwave focused thermal therapy device and system for tumor treatment. Background Art

[0002] Microwave hyperthermia is a medical technology that uses electromagnetic waves to interact with tissues to concentrate energy on the lesion to ablate or destroy tumor cells. Currently, microwave hyperthermia is widely used in tumor treatment due to its advantages in efficacy, safety and non-invasiveness.

[0003] Traditional microwave hyperthermia devices often produce "scattering" phenomena due to the difficulty in accurately focusing energy, resulting in damage to healthy tissue. In addition, if there is a lack of effective cooling mechanism during microwave hyperthermia, it may cause local overheating and increase the risk of complications. At the same time, most traditional microwave hyperthermia devices rely on manual parameter setting and adjustment, which makes it difficult to quickly respond to complex clinical needs.

[0004] Therefore, there is an urgent need for a microwave focused thermal therapy device and system for tumor treatment to solve at least one of the above problems. Summary of the invention

[0005] The present application provides a microwave energy-focusing hyperthermia device and system for tumor treatment, which aims to solve the problem that traditional microwave hyperthermia devices often produce "scattering" due to the difficulty in accurately focusing energy, resulting in damage to healthy tissue. In addition, if there is a lack of an effective cooling mechanism during microwave hyperthermia, it may cause local overheating and increase the risk of complications. At the same time, traditional microwave hyperthermia equipment mostly relies on manual parameter setting and adjustment, which makes it difficult to quickly respond to complex clinical needs.

[0006] In a first aspect, the present application provides a microwave focused thermal therapy system for tumor treatment, comprising:

[0007] A microwave transmitting module, wherein the microwave transmitting module is arranged toward the tumor tissue to be treated, and a transmitting port of the microwave transmitting module is used to transmit microwaves toward the tumor tissue, and the microwaves are used to heat the tumor tissue;

[0008] An energy-focusing waveguide module, which is arranged in front of the emission port and is used to focus the microwaves on the tumor area;

[0009] A cooling module, the cooling module is arranged around the launch port to form a cooling channel around the launch port;

[0010] An information acquisition module, the information acquisition module is used to acquire sensing information and image information of the tumor tissue;

[0011] A control module, wherein the control module is respectively connected to the microwave transmitting module, the cooling module and the information acquisition module for communication, and the control module is used to generate microwave frequency information, temperature adjustment information and a target area according to the sensing information and image information sent by the information acquisition module before the microwave transmitting module transmits the microwave to the tumor tissue, wherein the target area is located in the tumor tissue; and the control module is used to control the microwave transmitting module to transmit the microwave toward the target area according to the microwave frequency information, and to adjust the power of the cooling module according to the temperature adjustment information.

[0012] In some embodiments, the sensing information includes temperature information and pressure information, and the image information includes tissue image information and medical imaging information; the information acquisition module includes: a temperature sensing component, which is used to monitor the temperature information of the tumor tissue; a pressure sensing component, which is used to monitor the pressure information of the tumor tissue; an image acquisition component, which is set toward the tumor tissue and is used to acquire tissue image information of the tumor tissue; an image acquisition component, which is set toward the tumor tissue and is used to acquire medical imaging information corresponding to the tumor tissue; wherein the image acquisition component includes at least an ultrasound device and / or a magnetic resonance imaging device.

[0013] Exemplarily, the control module obtains tumor boundary information and tumor morphology information based on the tissue image information and the medical imaging information, so as to determine the target area in the tumor tissue based on the tumor boundary information, tumor morphology information and pressure information; the control module also generates the microwave frequency information based on the area information, tumor morphology information and temperature information of the target area; the control module also determines the temperature change information after the microwave emission based on the microwave frequency information, temperature information and tumor morphology information, so as to generate the temperature adjustment information based on the temperature change information and a preset target temperature.

[0014] Exemplarily, the control module further obtains the tissue thermal conductivity value, dielectric constant and morphological factor corresponding to the tumor tissue according to the tissue image information and tumor morphological information; the control module generates a thermal conductivity correction coefficient according to the tissue thermal conductivity value; the control module generates the microwave frequency information according to a preset target temperature, thermal conductivity correction coefficient, temperature information, dielectric constant, morphological factor, area information of the target area and a preset basic frequency, wherein the basic frequency is the lowest starting frequency corresponding to microwave focused thermal therapy; the expression of the microwave frequency information includes:

[0015] ;

[0016] Wherein, F is the value corresponding to the microwave frequency information, is the fundamental frequency, is the value corresponding to the area information, is the morphological factor, is the target temperature, is the value corresponding to the temperature information, is the dielectric constant, is the thermal conductivity correction coefficient, is the first adjustment coefficient, is the second adjustment coefficient.

[0017] Exemplarily, the temperature sensing component is also used to monitor the peripheral temperature information of the surrounding tissue corresponding to the tumor tissue, and the cooling module is also arranged toward the surrounding tissue; wherein, the control module receives the peripheral temperature information sent by the temperature sensing component, and if the peripheral temperature information is greater than or equal to a preset maximum temperature, the control module controls the cooling module to adjust the temperature of the surrounding tissue until the peripheral temperature information is less than the maximum temperature.

[0018] In some embodiments, the microwave transmitting module includes: a solid-state microwave generator, which is used to generate the microwave; a frequency control circuit, which is electrically connected to the solid-state microwave generator and is also communicatively connected to the control module, and is used to adjust the frequency of the solid-state microwave generator according to the microwave frequency information sent by the control module; a power amplifier, which is electrically connected to the solid-state microwave generator and is used to increase the power of the microwave; a transmitting antenna, which is used to transmit the amplified microwave to the target tissue through the energy focusing waveguide module; wherein the transmitting antenna includes any one of a horn antenna or a patch antenna; an antenna matching network, which is electrically connected to the solid-state microwave generator and the transmitting antenna, and is used to obtain the impedance information of the solid-state microwave generator, so as to adjust the impedance of the transmitting antenna according to the impedance information, and ensure that the impedance of the transmitting antenna matches the impedance of the solid-state microwave generator.

[0019] In some embodiments, the energy focusing waveguide module includes: a conical waveguide component, the conical waveguide component includes a circular entrance and a conical exit, the circular entrance is connected to the emission port, and the conical exit is arranged toward the target tissue, and when the microwave enters the circular entrance, a waveguide channel is formed inside the conical waveguide component; a dielectric mirror, the dielectric mirror is located in the middle position of the waveguide channel and / or close to the conical exit, and is used to focus the microwave; wherein the conical waveguide component is made of polytetrafluoroethylene material or ferrite material.

[0020] In some embodiments, the system further includes: a rotation module, which is connected to the microwave transmitting module and is used to control the direction of the transmitting port of the microwave transmitting module; wherein the rotation module is also communicatively connected to the control module, and the control module is used to generate adjustment position information according to the position information corresponding to the target area and the position information corresponding to the microwave transmitting module, so as to control the rotation module to rotate according to the adjustment position information so that the transmitting port faces the target area.

[0021] In a second aspect, an embodiment of the present application provides a method for microwave focused thermal therapy for tumor treatment, which is applied to a control module of a microwave focused thermal therapy system for tumor treatment provided in any embodiment of the present application; the method comprises:

[0022] Before the microwave transmitting module transmits microwaves to the tumor tissue, the sensing information and image information sent by the information collecting module are obtained;

[0023] generating microwave frequency information, temperature regulation information and a target area according to the sensing information, wherein the target area is located in the tumor tissue;

[0024] Controlling the microwave transmitting module to transmit microwaves toward the target area according to the microwave frequency information;

[0025] The power of the cooling module is adjusted according to the temperature adjustment information to complete the microwave focused heat therapy for the tumor tissue.

[0026] In a third aspect, an embodiment of the present application provides a microwave focused energy thermal therapy device for tumor treatment, which is applied to a control module of a microwave focused energy thermal therapy system for tumor treatment provided in any embodiment; the device comprises:

[0027] An information acquisition unit, used for acquiring the sensing information and image information sent by the information acquisition module before the microwave emission module emits microwaves to the tumor tissue;

[0028] an information generating unit, configured to generate microwave frequency information, temperature adjustment information and a target area according to the sensing information, wherein the target area is located in the tumor tissue;

[0029] A microwave transmitting unit, used for controlling the microwave transmitting module to transmit the microwave toward the target area according to the microwave frequency information;

[0030] The thermal therapy completion unit is used to adjust the power of the cooling module according to the temperature adjustment information to complete the microwave focused thermal therapy of the tumor tissue.

[0031] The present application provides a microwave energy-concentrating thermal therapy device and system for tumor treatment, the system includes a microwave transmitting module, an energy-concentrating waveguide module, a cooling module, an information acquisition module and a control module. The microwave transmitting module is arranged toward the tumor tissue to be treated, and the transmitting port of the microwave transmitting module is used to transmit microwaves to the tumor tissue, and the microwaves are used to heat the tumor tissue; the energy-concentrating waveguide module is arranged in front of the transmitting port, and is used to concentrate the microwaves in the tumor area; the cooling module is arranged around the transmitting port to form a cooling channel at the periphery of the transmitting port; the information acquisition module is used to collect the sensing information and image information of the tumor tissue; the control module is respectively connected to the microwave transmitting module, the cooling module and the information acquisition module for communication, and the control module is used to generate microwave frequency information, temperature adjustment information and target area according to the sensing information and image information sent by the information acquisition module before the microwave transmitting module transmits microwaves to the tumor tissue, and the target area is located in the tumor tissue; the control module is used to control the microwave transmitting module to transmit microwaves toward the target area according to the microwave frequency information, and adjust the power of the cooling module according to the temperature adjustment information.

[0032] The microwave transmitting module directly faces the tumor tissue to be treated and transmits microwaves through its transmitting port. These microwaves are used to heat the tumor tissue and play a therapeutic role. At the same time, the energy-gathering waveguide module is arranged in front of the microwave transmitting port, and its function is to gather the emitted microwaves in the tumor area, improve the utilization efficiency of microwaves, and enhance the heating effect on the tumor. The cooling module is arranged around the microwave transmitting port to form a cooling channel. The function of this module is to protect normal tissues from thermal damage by controlling the temperature of the cooling channel. The information acquisition module is used to collect the sensing information and image information of the tumor tissue and provide data support for subsequent operations. The control module is the core of the entire device and is responsible for communicating with the microwave transmitting module, the cooling module and the information acquisition module. Its functions include: before transmitting microwaves, according to the sensing information and image information provided by the information acquisition module, generating microwave frequency information, temperature adjustment information and determining the target area. Control the microwave transmitting module to transmit microwaves to the target area according to the generated microwave frequency information. According to the temperature adjustment information, adjust the power of the cooling module to ensure the safety and effectiveness of the treatment.

[0033] The system provided thereby has at least the following beneficial effects:

[0034] 1. Precision treatment: Through the real-time data provided by the information acquisition module, the control module can accurately locate the target area of ​​the tumor and achieve more accurate microwave thermal therapy.

[0035] 2. High safety: The addition of the cooling module and the real-time power adjustment by the control module can effectively protect normal tissues and reduce side effects.

[0036] 3. Improved efficiency: The setting of the energy-focusing waveguide module significantly improves the microwave focusing effect and enhances the thermal therapeutic efficiency on tumors.

[0037] 4. Intelligent control: The control module automatically adjusts the microwave frequency and cooling power to simplify operation and improve treatment effect and safety.

[0038] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0040] Figure 1 This is a schematic block diagram of the structure of a microwave focused thermal therapy system for tumor treatment shown in an embodiment of the present application;

[0041] Figure 2 This is a schematic flow chart of the steps of a microwave focused thermal therapy method for tumor treatment according to an embodiment of the present application;

[0042] Figure 3 This is a schematic diagram of the structure of a microwave focused thermal therapy device for tumor treatment shown in an embodiment of the present application;

[0043] Figure 4 This is a schematic block diagram of the structure of a control module shown in an embodiment of the present application.

[0044] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application. DETAILED DESCRIPTION

[0045] In the following description, specific details such as specific system structures, technologies, etc. are provided for the purpose of illustration rather than limitation, so as to provide a thorough understanding of the embodiments of the present application. However, it should be clear to those skilled in the art that the present application may also be implemented in other embodiments without these specific details. In other cases, detailed descriptions of well-known systems, systems, circuits, and methods are omitted to prevent unnecessary details from obstructing the description of the present application.

[0046] It should be understood that when used in the present specification and the appended claims, the term "comprising" indicates the presence of described features, wholes, steps, operations, elements and / or components, but does not exclude the presence or addition of one or more other features, wholes, steps, operations, elements, components and / or combinations thereof.

[0047] It should also be understood that the term “and / or” used in the specification and appended claims refers to any and all possible combinations of one or more of the associated listed items, and includes these combinations.

[0048] As used in the specification and appended claims of this application, the term "if" can be interpreted as "when" or "uponce" or "in response to determining" or "in response to detecting", depending on the context. Similarly, the phrase "if it is determined" or "if [described condition or event] is detected" can be interpreted as meaning "uponce it is determined" or "in response to determining" or "uponce [described condition or event] is detected" or "in response to detecting [described condition or event]", depending on the context.

[0049] In addition, in the description of the present application specification and the appended claims, the terms "first", "second", "third", etc. are only used to distinguish the descriptions and cannot be understood as indicating or implying relative importance.

[0050] References to "one embodiment" or "some embodiments" etc. described in the specification of this application mean that one or more embodiments of the present application include specific features, structures or characteristics described in conjunction with the embodiment. Therefore, the statements "in one embodiment", "in some embodiments", "in some other embodiments", "in some other embodiments", etc. that appear in different places in this specification do not necessarily refer to the same embodiment, but mean "one or more but not all embodiments", unless otherwise specifically emphasized in other ways. The terms "including", "comprising", "having" and their variations all mean "including but not limited to", unless otherwise specifically emphasized in other ways.

[0051] The technical solution of the embodiment of the present application is introduced below.

[0052] Microwave hyperthermia is a medical technology that uses electromagnetic waves to interact with tissues to concentrate energy on the lesion to ablate or destroy tumor cells. Currently, microwave hyperthermia is widely used in tumor treatment due to its advantages in efficacy, safety and non-invasiveness.

[0053] Traditional microwave hyperthermia devices often produce "scattering" phenomena due to the difficulty in accurately focusing energy, resulting in damage to healthy tissue. In addition, if there is a lack of effective cooling mechanism during microwave hyperthermia, it may cause local overheating and increase the risk of complications. At the same time, most traditional microwave hyperthermia devices rely on manual parameter setting and adjustment, which makes it difficult to quickly respond to complex clinical needs.

[0054] Therefore, there is an urgent need for a microwave focused thermal therapy device and system for tumor treatment to solve at least one of the above problems.

[0055] Please refer to Figure 1 , Figure 1 FIG. 1 is a schematic block diagram of the structure of a microwave focused thermal therapy system 10 for tumor treatment according to an embodiment of the present application. Figure 1 As shown, the provided microwave energy-concentrating thermal therapy system 10 includes a microwave transmitting module 11, an energy-concentrating waveguide module 12, a control module 13, an information acquisition module 14 and a cooling module 15. The microwave transmitting module 11 is arranged toward the tumor tissue to be treated, and the transmitting port of the microwave transmitting module 11 is used to transmit microwaves to the tumor tissue, and the microwaves are used to heat the tumor tissue; the energy-concentrating waveguide module is arranged in front of the transmitting port, and is used to concentrate the microwaves in the tumor area; the cooling module 15 is arranged around the transmitting port to form a cooling channel at the periphery of the transmitting port; the information acquisition module 14 is used to collect the sensing information and image information of the tumor tissue; the control module 13 is respectively connected to the microwave transmitting module 11, the cooling module 15 and the information acquisition module 14 for communication, and the control module 13 is used to generate microwave frequency information, temperature adjustment information and target area according to the sensing information and image information sent by the information acquisition module 14 before the microwave transmitting module 11 transmits microwaves to the tumor tissue, and the target area is located in the tumor tissue; the control module 13 is used to control the microwave transmitting module 11 to transmit microwaves toward the target area according to the microwave frequency information, and adjust the power of the cooling module 15 according to the temperature adjustment information.

[0056] Specifically, the provided microwave energy focused hyperthermia system 10 is a medical device for improving the accuracy and safety of microwave hyperthermia. Its microwave transmitting module 11 is used to transmit microwaves to tumor tissues, and the microwaves heat the tumor tissues through thermal effects. The transmitting module is designed to accurately target the tumor area. Through accurate microwave emission, the damage to surrounding healthy tissues is reduced, and the accuracy of treatment is improved.

[0057] The energy-gathering waveguide module 12 is located in front of the microwave emission port (such as Figure 1 The cone part in the center of the tumor is used to gather and guide microwave energy to ensure that the energy is concentrated in the tumor area. This can avoid the dispersion of microwave energy, maximize energy utilization, improve treatment effects and reduce the impact on surrounding healthy tissues.

[0058] The control module 13 is in communication with the microwave emission module 11, the cooling module 15 and the information acquisition module 14. According to the data provided by the information acquisition module, microwave frequency information and temperature adjustment information are generated, and the target area is determined. Intelligent control of microwave emission and cooling is achieved to ensure that the temperature is appropriate during the treatment process, optimize the treatment parameters, and improve the automation and response speed of the operation.

[0059] The information acquisition module 14 acquires the sensing information and image information of the tumor tissue, which is used to evaluate the characteristics of the diseased tissue and the treatment position, so as to provide data support for the adjustment of treatment parameters in real time and improve the pertinence and safety of the treatment.

[0060] The cooling module 15 surrounds the microwave emission port to form a cooling channel. The cooling intensity is adjusted according to the instruction of the control module 13. It can effectively prevent local overheating, reduce the risk of surrounding tissue damage and complications, and improve the safety and comfort of patients.

[0061] In actual use, the modules of the system work together: the information acquisition module first captures and transmits real-time data of the tumor, and the control module 13 intelligently calculates and sets the frequency and path of the microwave based on this data, while adjusting the temperature of the cooling module to prevent overheating. The microwave emission module 11 accurately focuses and transmits microwave energy to the tumor area, achieving the best treatment effect through an efficient energy concentration mechanism. This integrated design not only improves the accuracy and safety of microwave hyperthermia, but also reduces manual intervention through automatic adjustment functions, quickly responds to clinical needs, and improves the overall intelligence level of the equipment.

[0062] In some embodiments, the sensing information includes temperature information and pressure information, and the image information includes tissue image information and medical imaging information; the information acquisition module 14 includes: a temperature sensing component, which is used to monitor the temperature information of the tumor tissue; a pressure sensing component, which is used to monitor the pressure information of the tumor tissue; an image acquisition component, which is set toward the tumor tissue and is used to acquire tissue image information of the tumor tissue; an image acquisition component, which is set toward the tumor tissue and is used to acquire medical imaging information corresponding to the tumor tissue; wherein the image acquisition component at least includes an ultrasound device and / or a magnetic resonance imaging device.

[0063] This embodiment aims to obtain the real-time status of tumor tissue more accurately through the design of the composition and function of the information acquisition module 14, so as to guide the decision-making during the thermal treatment process. The temperature sensing component is used to monitor the real-time temperature information of the tumor tissue. Devices such as thermocouples or infrared temperature sensors can be used to accurately record the temperature changes of the tissue.

[0064] The pressure sensing component is used to monitor the pressure information of tumor tissue. A micro pressure sensor can be used to detect internal or external pressure changes in tumor tissue.

[0065] The image acquisition component collects tissue image information of tumor tissue. Clear tissue images can be obtained through high-definition camera equipment, microscope imaging system and other equipment.

[0066] Image acquisition component: Obtain medical image information corresponding to tumor tissue. Including ultrasound equipment and / or magnetic resonance imaging (MRI) equipment, providing high-resolution medical images. Ultrasound equipment uses sound waves to quickly obtain soft tissue information; MRI provides more detailed soft tissue pairs to achieve fine structural mapping.

[0067] Then, through the real-time data feedback of temperature and pressure, the microwave emission parameters and cooling process can be adjusted more accurately to avoid overheating or tissue damage. The combination of tissue image information and medical imaging information provides doctors with detailed tumor anatomical structure and position relationship, assists in judging the treatment plan and achieves precise positioning during the treatment process. At the same time, during the thermal therapy process, it can obtain instant feedback on the treatment effect, and adjust the treatment strategy in time when necessary to improve the efficacy. During the treatment process, the temperature sensing component in the system monitors the temperature of the tumor area in real time. When the temperature is higher than the set threshold, the control module can automatically adjust the microwave intensity or start the cooling module. Through ultrasound equipment, the internal dynamic changes of tumor tissue can be observed in real time, which not only assists in confirming the treatment position, but also monitors whether the tissue response during the treatment process is normal. The use of MRI equipment provides high-contrast images for preoperative planning and intraoperative confirmation, especially in the treatment of cancerous tissue in complex or deep parts, providing important imaging guidance.

[0068] Through the above-mentioned technical implementations and functions, this embodiment not only improves the accuracy and safety of operation in the microwave focused thermal therapy device, but also enhances the flexibility in clinical application and comprehensively optimizes the tumor treatment effect.

[0069] Exemplarily, the control module 13 obtains tumor boundary information and tumor morphology information based on the tissue image information and the medical imaging information, so as to determine the target area in the tumor tissue based on the tumor boundary information, tumor morphology information and pressure information; the control module 13 also generates the microwave frequency information based on the area information, tumor morphology information and temperature information of the target area; the control module 13 also determines the temperature change information after the microwave emission based on the microwave frequency information, temperature information and tumor morphology information, so as to generate the temperature adjustment information based on the temperature change information and a preset target temperature.

[0070] The control module 13 uses multiple information sources to accurately determine the treatment target area and optimize the microwave emission parameters. The optimization process corresponding to this example can greatly improve the accuracy and safety of microwave thermal therapy.

[0071] First, the control module 13 accurately identifies the boundary and morphology of the tumor based on the tissue image information and medical image information. This may involve complex image processing algorithms, such as edge detection and 3D reconstruction technology. Combined with the obtained tumor boundary information, tumor morphology information and pressure information, the target area in the tumor that needs to be heated is accurately located. This process requires the fusion and analysis of the above data to identify the most suitable treatment area.

[0072] At the same time, based on the size of the target area, combined with the tumor morphology and real-time temperature data, the most suitable microwave frequency is automatically generated. This process may involve calculating the wavelength that meets the specific heating depth and range. Based on the microwave frequency, temperature information and tumor morphology, the possible temperature changes after microwave emission are predicted, and the corresponding temperature adjustment information is generated based on the comparison between the actual changes and the preset target temperature.

[0073] Through the integration of multi-dimensional information, the actual boundaries and morphology of the tumor can be accurately defined, helping to formulate personalized treatment strategies. At the same time, the system automatically adjusts the microwave frequency and temperature according to real-time data, making the treatment process more intelligent, reducing human operating errors and improving treatment effects. By predicting and adjusting the temperature changes after microwave emission, overheating and damage to surrounding healthy tissues can be prevented, increasing the safety of treatment.

[0074] It should be noted that, since the tumor boundary is rough and irregular, the control module 13 determines the precise boundary of the tumor through image data analysis. Even in the case of irregular shape, it can accurately identify the target area to be treated and adjust the microwave frequency to best adapt to the depth and characteristics of different areas.

[0075] At the same time, during the thermal treatment process, the control module 13 monitors the temperature changes in the target area in real time and automatically adjusts the microwave output and cooling intensity. For example, when the temperature rises too quickly, the system can immediately reduce the microwave power or increase the cooling to ensure effective thermal treatment within a safe range.

[0076] Accordingly, in response to dynamic adjustments under different tissue resistance conditions, the control module 13 uses pressure information to detect resistance changes in different tissues and predict the conduction of microwaves in these tissues to adjust microwave frequency and power distribution, thereby improving the effectiveness of treatment.

[0077] Through the content of this example, the entire microwave thermal therapy process becomes more precise and controllable, and can better adapt to various complex clinical situations, significantly improving the effect of tumor treatment and the patient's safety experience.

[0078] It should be noted that, in some embodiments, determining the target area through tumor boundary information, tumor morphology information and pressure information is a multi-factor comprehensive analysis process. For example, medical imaging technologies such as CT, MRI or ultrasound are used to obtain tumor boundary data. Image processing algorithms (such as edge detection and segmentation algorithms) are used to extract accurate tumor boundaries.

[0079] Secondly, through three-dimensional reconstruction technology, a complete tumor morphology model is formed to extract morphological features such as volume, surface area, shape complexity, etc.

[0080] Pressure information may come from pressure sensors within the tissue or from predictive models based on tissue properties. By analyzing the pressure distribution map, pressure differences in different areas can be identified, with special attention paid to high pressure and its adjacent areas.

[0081] Combining the three types of information, the control module 13 determines the correlation between different parameters and the impact on the definition of the target area through multivariate analysis methods, such as machine learning algorithms, statistical models, etc. The three-dimensional model is used to spatially locate each point in the tumor, and the potential target area is preliminarily screened out in combination with the boundary and morphological information. In the preliminary area, the pressure information is used as the weight to further subdivide and adjust the position and range of the target area, especially considering the pressure difference between the inside and outside of the tumor. Finally, an optimization algorithm (such as a genetic algorithm, simulated annealing, etc.) is used to further optimize the area selection to ensure that the selection of the target area is as effective as possible for treatment and protects healthy tissue. It may also be compared with historical data, and revised and improved using expert systems or manual annotation experience. Using computer simulation technology, a virtual treatment simulation is performed on the selected target area to ensure that the expected treatment effect can be achieved. The simulation may include detailed analysis of heat conduction, tissue reaction and peripheral influences. In the actual treatment process, with the help of real-time feedback data, the target area is modified as necessary using a dynamic adjustment algorithm to adapt to physiological changes that may occur at any time. Through these steps, the system can combine the morphological characteristics and biomechanical characteristics of the tumor to complete the precise positioning of the target area in the tumor, which is crucial for subsequent effective treatment.

[0082] At the same time, the target area obtains the scoring information of each point in the tumor tissue and determines whether the point is located in the target area according to the scoring information. The expression of the scoring information includes:

[0083] ;

[0084] ;

[0085] ;

[0086] ;

[0087] in, For each of the points, the scoring information corresponding to the are the coordinates of the point, is the boundary factor corresponding to the point, is the morphological factor corresponding to the point, is the pressure factor corresponding to the point, , , The distribution is boundary threshold, morphological threshold and pressure threshold, Indicate point The distance to the nearest tumor border, is a constant that prevents the denominator from being zero. Indicate point The curvature of and Respectively represent the average curvature and standard deviation of multiple points in the tumor area, represents the gradient operator, Indicate point pressure value.

[0088] By calculating for each point in the tumor area , select the area with the highest score as the key target area for hyperthermia. Adjust the , , The value of the MRI scan can be adjusted to suit specific pathological characteristics. By integrating multiple physical characteristics to support multi-dimensional comprehensive decision-making, it helps to improve the precise positioning and execution efficiency of treatment plans.

[0089] Exemplarily, the control module 13 further obtains the tissue thermal conductivity value, dielectric constant and morphological factor corresponding to the tumor tissue according to the tissue image information and the tumor morphological information; the control module 13 generates a thermal conductivity correction coefficient according to the tissue thermal conductivity value; the control module 13 generates the microwave frequency information according to the preset target temperature, thermal conductivity correction coefficient, temperature information, dielectric constant, morphological factor, area information of the target area and a preset basic frequency, wherein the basic frequency is the lowest starting frequency corresponding to microwave concentrated energy thermal therapy; the expression of the microwave frequency information includes:

[0090] ;

[0091] Wherein, F is the value corresponding to the microwave frequency information, is the fundamental frequency, is the value corresponding to the area information, is the morphological factor, is the target temperature, is the value corresponding to the temperature information, is the dielectric constant, is the thermal conductivity correction coefficient, is the first adjustment coefficient, is the second adjustment coefficient.

[0092] This example describes in detail how to dynamically adjust the microwave frequency to optimize the thermal therapy effect by comprehensively considering multiple physical parameters. The tissue thermal conductivity value reflects the ability of the tissue to conduct heat, which is usually obtained through experimental data or known literature values. The dielectric constant involves the tissue's ability to respond to electromagnetic waves, and the morphological factor describes the effect of the tumor shape on the thermal therapy effect. The control module 13 generates a correction coefficient based on the tissue thermal conductivity value to adjust the thermal conduction effect in the calculation. During this calculation process, the control module 13 integrates the influence of different parameters through the above expression and generates the optimal microwave frequency information.

[0093] Then, by introducing parameters such as thermal conductivity and dielectric constant, the device can be adjusted according to the characteristics of different individual tissues to achieve personalized treatment. In the context of high thermal conductivity around the tumor, by adjusting the thermal conductivity correction coefficient, the system can effectively reduce the upper limit of microwave frequency and reduce the impact of heat diffusion on surrounding tissues. By using dynamically adjusted microwave frequency, microwave energy can be more effectively concentrated in the target area, reducing the impact on surrounding healthy tissues. At the same time, by comprehensively considering thermal and electromagnetic properties, the setting of microwave frequency is optimized, making the treatment effect more significant and less side effects. If the tumor is irregular in shape, the morphological factor will reflect the complexity of the shape. The control module 13 optimizes the microwave concentration effect by adjusting the influence of the morphological factor to ensure uniform heating of all areas. At the same time, during the treatment process, if the external temperature changes or the internal temperature fluctuates greatly, the microwave frequency can be dynamically adjusted by adjusting the influence of the temperature difference to maintain the stability of the treatment. In general, the above example realizes the fine adjustment of microwave frequency by integrating multiple influencing factors, which significantly improves the accuracy, safety and effectiveness of microwave energy-concentrated thermal therapy.

[0094] Exemplarily, the temperature sensing component is also used to monitor the peripheral temperature information of the surrounding tissue corresponding to the tumor tissue, and the cooling module 15 is also set toward the surrounding tissue; wherein, the control module 13 receives the peripheral temperature information sent by the temperature sensing component, and if the peripheral temperature information is greater than or equal to a preset maximum temperature, the control module 13 controls the cooling module 15 to adjust the temperature of the surrounding tissue until the peripheral temperature information is less than the maximum temperature.

[0095] The above example embodies a dynamic cooling mechanism for protecting healthy tissue around the tumor, further improving the safety and accuracy of thermal therapy. In addition to monitoring the temperature of the tumor tissue itself, the temperature sensing component is also responsible for monitoring the temperature information of the tissue around the tumor. Non-contact infrared temperature sensors or contact multi-point thermocouple sensors can be used to provide comprehensive temperature monitoring around the tumor.

[0096] At the same time, cooling support is provided for the surrounding tissues to prevent the surrounding healthy tissues from being damaged due to excessive temperature. The cooling module 15 may include a liquid circulation cooling system or a compressed air cooling device, which is directly directed to the surrounding tissues that need to be protected. The control module 13 implements dynamic cooling management by continuously receiving and analyzing the surrounding temperature information sent by the temperature sensing component. Once it is detected that the surrounding temperature is equal to or exceeds the preset maximum safe temperature, the control module 13 immediately activates the cooling module 15 and adjusts the temperature until it drops back to a safe level.

[0097] Through dynamic monitoring and rapid response, it is ensured that the healthy tissue around the tumor will not be damaged due to excessive temperature during the thermal treatment process. The coordinated work of the cooling module 15 and the control module makes the entire process without manual intervention, and maintains the normal temperature more reliably and efficiently. This technology can adapt to different tissue characteristics and complex lesion environments, and is widely used in clinical situations with high requirements for surrounding tissues.

[0098] For example, during thermal therapy, if the tumor is located close to important organs (such as the heart or nervous system), the temperature sensing component can quickly monitor temperature changes in the area and accurately control the temperature through the cooling module to avoid accidental injury.

[0099] At the same time, when it is necessary to treat a larger area or multiple small tumor clusters, peripheral tissue temperature management is particularly important. The precise control of the cooling module ensures that the peripheral temperature is always within a safe range during large-area heating. During the treatment process, if the control module 13 detects a sudden rise in temperature at a certain moment or area, the cooling module will immediately intervene to ensure that the temperature drops rapidly. This rapid response mechanism can significantly reduce potential treatment complications.

[0100] Through the above examples, the system can not only effectively concentrate thermal energy to treat tumors, but also protect surrounding healthy tissues, avoid the negative effects caused by heat diffusion, and effectively improve the safety of treatment and the comfort of patients.

[0101] In some embodiments, the microwave transmitting module 11 includes: a solid-state microwave generator, which is used to generate the microwave; a frequency control circuit, which is electrically connected to the solid-state microwave generator and is also communicatively connected to the control module 13, and is used to adjust the frequency of the solid-state microwave generator according to the microwave frequency information sent by the control module 13; a power amplifier, which is electrically connected to the solid-state microwave generator and is used to increase the power of the microwave; a transmitting antenna, which is used to transmit the amplified microwave to the target tissue through the energy focusing waveguide module 12; wherein the transmitting antenna includes any one of a horn antenna or a patch antenna; an antenna matching network, which is electrically connected to the solid-state microwave generator and the transmitting antenna, and is used to obtain the impedance information of the solid-state microwave generator, so as to adjust the impedance of the transmitting antenna according to the impedance information, and ensure that the impedance of the transmitting antenna matches the impedance of the solid-state microwave generator.

[0102] This embodiment is a basic component design for realizing a microwave therapeutic device, with a particular focus on the entire process of microwave generation, frequency control, power amplification and effective emission.

[0103] The solid-state microwave generator is responsible for generating the required microwave signal. Compared with the traditional electron tube microwave source, the solid-state microwave generator has higher reliability, stability and smaller size.

[0104] The frequency control circuit is electrically connected to the solid-state microwave generator, and adjusts the microwave frequency in real time according to the microwave frequency information sent by the control module, such as through a phase-locked loop (PLL) circuit or a voltage-controlled oscillator (VCO), to achieve precise frequency control and ensure stable signal output.

[0105] The power amplifier is used to increase the output power of microwaves to reach the energy level required for treatment. High-efficiency power amplification technology, such as GaN (Gallium Nitride) or LDMOS (Laterally Diffused Metal Oxide Semiconductor) amplifiers, is used to achieve high efficiency and high linearity.

[0106] The transmitting antenna includes either a horn antenna or a patch antenna, which is used to effectively transmit the microwave after power amplification to the target tissue through the energy-focusing waveguide module. The horn antenna is suitable for applications that require greater coverage and directivity, while the patch antenna is conducive to smaller integration and can be selected according to needs.

[0107] The antenna matching network obtains the impedance information of the solid-state microwave generator and dynamically adjusts the impedance of the transmitting antenna to ensure impedance matching between the two. The design of the matching network can maximize energy transmission efficiency, reduce reflection loss, and improve system performance.

[0108] Then, through the coordinated action of the solid-state microwave generator and the frequency control circuit, a microwave output with stable frequency and controllable power is achieved. The power amplifier and antenna matching network improve the efficiency of power transmission and RF energy utilization, ensuring less energy loss and higher treatment efficiency. The frequency control and impedance matching functions enable the system to adapt to different tissue characteristics and treatment needs.

[0109] For example, in tumor ablation applications, this system can be used to adjust the required microwave frequency and power to accurately destroy tumor cells and minimize the impact on surrounding healthy tissues. In laboratory tests, the system's effective thermal effect and efficient energy transfer capabilities for different prostheses and tissue samples were demonstrated by adjusting the frequency and antenna impedance. The system can be used in a variety of microwave treatment scenarios, such as in vitro cosmetic treatments for eliminating local fat and for combating microbial disinfection, because it can finely control microwave parameters to adapt to different treatment needs. This embodiment integrates a solid-state microwave generator and an efficient antenna transmission system to construct an efficient, stable, and flexible microwave treatment platform that can meet diverse clinical needs.

[0110] In some embodiments, the energy focusing waveguide module 12 includes: a conical waveguide component, the conical waveguide component includes a circular entrance and a conical exit, the circular entrance is connected to the emission port, and the conical exit is arranged toward the target tissue, and when the microwave enters the circular entrance, a waveguide channel is formed inside the conical waveguide component; a dielectric mirror, the dielectric mirror is located in the middle position of the waveguide channel and / or close to the conical exit, and is used to focus the microwave; wherein the conical waveguide component is made of polytetrafluoroethylene material or ferrite material.

[0111] This embodiment focuses on the design and application of an energy-gathering waveguide module for microwave therapy. The tapered waveguide has a circular inlet and a tapered outlet. The geometric deformation of the tapered structure from the circular inlet to the tapered outlet gradually gathers and guides microwaves to ensure more efficient energy transfer. By using polytetrafluoroethylene (PTFE) material or ferrite material, their excellent dielectric properties and high temperature resistance are utilized to improve the waveguide efficiency.

[0112] Microwaves enter from the circular inlet and form a waveguide channel in the conical structure. As the conical structure gradually converges, the microwave energy is gathered and directed toward the target tissue through the conical outlet.

[0113] The dielectric mirror is located in the middle of the waveguide channel and / or at the conical exit, and its function is to focus the microwaves.

[0114] By making use of its dielectric properties, the phase and amplitude of the microwaves are adjusted so that the microwave energy is more concentrated after leaving the conical outlet, thereby improving the treatment efficiency.

[0115] The conical waveguide effectively focuses microwave energy through its geometric structure, reduces energy loss, and enhances microwave penetration. The addition of dielectric mirrors optimizes the microwave propagation path and energy focus, improving the pertinence and effectiveness of target tissue during treatment. PTFE and ferrite materials are used, which have excellent dielectric constants and magnetic permeabilities, helping to achieve higher waveguide efficiency and durability. By adjusting the position of the dielectric mirror and the design of the conical waveguide, the system can flexibly adapt to target areas of different sizes and depths.

[0116] For example, in deep tumor ablation treatment, this waveguide design allows microwaves to be focused more accurately on the lesion area, reducing the impact on surrounding healthy tissue. Through experiments, the size and intensity of the microwave focus point under different configurations were measured, and the results showed that the adjustment of the dielectric mirror can significantly increase the energy density in the thermal effect area. In the entire microwave treatment system, combined with the microwave transmission module of the first embodiment, this waveguide module can further improve the transmission efficiency and focusing accuracy of microwaves, providing synergy for different types of microwave treatments. This embodiment achieves more efficient and controllable microwave energy transfer by optimizing the waveguide design, and is suitable for treatment processes that require high-precision positioning, such as tumor ablation and local high-precision heat treatment.

[0117] In some embodiments, the system further includes: a rotation module, which is connected to the microwave transmitting module 11 and is used to control the direction of the emission port of the microwave transmitting module 11; wherein the rotation module is also communicatively connected to the control module 13, and the control module 13 is used to generate adjustment position information according to the position information corresponding to the target area and the position information corresponding to the microwave transmitting module 11, so as to control the rotation module to rotate according to the adjustment position information so that the emission port faces the target area.

[0118] This embodiment describes in detail the rotation module in the system, which is used to accurately control the emission direction of the microwave emission module to ensure that the microwave energy can be accurately transmitted to the target area. The rotation module is directly connected to the microwave emission module and is responsible for adjusting the direction of its emission port. This module adjusts the directivity of the microwave by processing the instructions provided by the control module. The module can achieve precise angle adjustment through motor drive, and a stepper motor or servo motor is often used to provide accuracy and flexibility. The rotation module is connected to the control module 13 in communication. The control module 13 obtains the position information of the target area and the microwave emission module, and generates corresponding adjustment position information to accurately guide the rotation module to position. Through sensor data or preset parameters, the relative position of the current microwave emission device and the target is calculated in real time, and control instructions are automatically generated. With the help of position sensors and image processing algorithms, the specific position and shape of the target area are identified, and the optimal emission angle is calculated. In dynamic surgery or treatment, the emission direction is automatically tracked and adjusted in time to ensure that the energy is continuously and stably directed to the target area.

[0119] By introducing the rotating module, the emission direction of microwaves can be adjusted in real time to ensure that the treatment energy is effectively concentrated on the diseased tissue and reduce the impact on the surrounding healthy tissue. Microwave treatment can be performed on difficult-to-reach deep locations in the body, improving the accessibility and effectiveness of treatment. It reduces manual operation errors and improves operational convenience and fault tolerance. The system can adapt to different treatment plans, especially for complex treatment scenarios in multiple directions and angles.

[0120] For example, during microwave ablation of a tumor, the rotating module can adjust the emission direction in real time to cover the tumor boundary, thereby achieving full coverage ablation. With the assistance of real-time imaging, the control module 13 can track and adjust the emission direction in real time during the operation, and maintain high-precision energy input even when the patient's position or organ position changes. At the same time, in a group of phantom experiments, the system equipped with a rotating module can significantly improve the coverage of microwaves to the designated target area and reduce the energy loss caused by the fixed emission direction.

[0121] This embodiment introduces an intelligent rotation adjustment mechanism to make the microwave treatment device highly adaptable and accurate, and is suitable for various treatment projects that require multi-directional microwave access, such as ablation surgery and local heating of deep tissues in the body.

[0122] The provided system has at least the following beneficial effects:

[0123] 1. Precision treatment: Through the real-time data provided by the information acquisition module, the control module can accurately locate the target area of ​​the tumor and achieve more accurate microwave thermal therapy.

[0124] 2. High safety: The addition of the cooling module and the real-time power adjustment by the control module can effectively protect normal tissues and reduce side effects.

[0125] 3. Improved efficiency: The setting of the energy-focusing waveguide module significantly improves the microwave focusing effect and enhances the thermal therapeutic efficiency on tumors.

[0126] 4. Intelligent control: The control module automatically adjusts the microwave frequency and cooling power to simplify operation and improve treatment effect and safety.

[0127] Please refer to Figure 2 , Figure 2 A schematic flow chart of the steps of a microwave focused energy thermal therapy method for tumor treatment provided in an embodiment of the present application. The microwave focused energy thermal therapy method for tumor treatment in an embodiment of the present application can be applied to a control module of a microwave focused energy thermal therapy device for tumor treatment provided in any embodiment of the present application, and the control module can be an MCU. Figure 2 As shown, the microwave focused thermal therapy method for tumor treatment in this embodiment includes steps S101 to S104, which are described in detail as follows:

[0128] Step S101, before the microwave emission module emits microwaves to the tumor tissue, the sensing information and image information sent by the information acquisition module are acquired.

[0129] Specifically, the information acquisition module is used to obtain sensing information (such as physical parameters detected by sensors) and image information (such as real-time images or scanned images) from the treatment area. The sensing information may include data such as the size, location, and characteristics of the surrounding tissues of the tumor, while the image information provides visual assistance to support the precise positioning of the target area. By providing accurate tissue characteristics and positioning information before treatment, a data basis is provided for the setting of subsequent microwave treatment parameters. The risk of accidental injury to normal tissues during treatment is reduced, and the accuracy and safety of treatment are improved.

[0130] Step S102, generating microwave frequency information, temperature adjustment information and a target area according to the sensing information, wherein the target area is located in the tumor tissue.

[0131] Specifically, based on the sensing information obtained in step S101, specific microwave frequency information and temperature adjustment information are generated. The target area in the tumor tissue is determined as the focus of microwave energy concentration to optimize the thermal therapy effect. By customizing the microwave frequency and temperature adjustment, personalized treatment for different tumor characteristics is achieved, and the energy utilization efficiency is improved. The targeted treatment is improved, not only tumor cells are accurately attacked, but also the temperature of the treatment area can be adjusted as needed, providing more effective treatment plans for different tumor types.

[0132] Step S103, controlling the microwave emission module to emit microwaves toward the target area according to the microwave frequency information.

[0133] Specifically, the control module adjusts the output parameters of the microwave emission module based on the generated microwave frequency information to accurately align it with the target area. This includes adjusting the microwave power, frequency, and emission angle to ensure that microwave energy is effectively transmitted to the target area. This improves the focusing accuracy and transmission efficiency of microwave energy, allowing the maximum energy to be concentrated in the tumor area, reducing energy waste and damage to surrounding healthy tissues. This ensures the continuity and stability of microwave treatment and improves the treatment effect.

[0134] Step S104, adjusting the power of the cooling module according to the temperature adjustment information to complete the microwave focused heat therapy for the tumor tissue.

[0135] Specifically, according to the temperature adjustment information, the power of the cooling module is dynamically adjusted to ensure that the temperature of the treatment area remains within the preset safety and efficacy range. The flexible adjustment of the cooling module helps manage the heat generated by microwaves to protect surrounding tissues and avoid the risk of overheating. By achieving real-time temperature management, a safe treatment environment is provided to prevent damage caused by overheating of tissues. Through temperature control, the comfort and safety of treatment are guaranteed, and the patient's treatment tolerance and overall effect are increased. Through the above steps, this microwave focused thermal therapy method provides a systematic, precise and safe tumor treatment plan, which not only improves the thermal effect on the target tumor, but also strengthens the ability to protect tissues and manage temperature during treatment.

[0136] The above-mentioned microwave focused heat therapy method for tumor treatment can implement any function implemented in the control module 14 of the above-mentioned system embodiment. The optional items in the above-mentioned system embodiment are also applicable to this embodiment and will not be described in detail here. The rest of the contents of the embodiment of this application can refer to the contents of the above-mentioned method embodiment, and will not be repeated in this embodiment.

[0137] In order to implement the microwave focused thermal therapy method for tumor treatment corresponding to the above method embodiment, to achieve the corresponding functions and technical effects. Figure 3 , Figure 3 The structure block diagram of a microwave focused energy thermal therapy device 200 for tumor treatment provided in an embodiment of the present application is shown. The system is applied to a control module of a microwave focused energy thermal therapy device for tumor treatment provided in any embodiment of the present application. For ease of description, only the parts related to the present embodiment are shown. The microwave focused energy thermal therapy device 200 for tumor treatment provided in an embodiment of the present application includes:

[0138] The information acquisition unit 201 is used to acquire the sensing information and image information sent by the information acquisition module before the microwave emission module emits microwaves to the tumor tissue;

[0139] An information generating unit 202, configured to generate microwave frequency information, temperature adjustment information and a target area according to the sensing information, wherein the target area is located in the tumor tissue;

[0140] A microwave transmitting unit 203, used for controlling the microwave transmitting module to transmit the microwave toward the target area according to the microwave frequency information;

[0141] The thermal therapy completion unit 204 is used to adjust the power of the cooling module according to the temperature adjustment information to complete the microwave focused thermal therapy of the tumor tissue.

[0142] The above-mentioned microwave concentrated energy thermal therapy device 200 for tumor treatment can implement the microwave concentrated energy thermal therapy method for tumor treatment in the above-mentioned method embodiment. The options in the above-mentioned method embodiment are also applicable to this embodiment and will not be described in detail here. The rest of the contents of the embodiment of this application can refer to the contents of the above-mentioned method embodiment, and will not be repeated in this embodiment.

[0143] Figure 4 This is a schematic diagram of the structure of a control module provided in one embodiment of the present application. Figure 4 As shown, the control module 13 of this embodiment includes: at least one processor 130 ( Figure 4 Only one is shown in the figure), a memory 131 and a computer program 132 stored in the memory 131 and executable on the at least one processor 130, wherein the processor 130 implements the steps of any of the above method embodiments when executing the computer program 132.

[0144] The control module 13 may be a microcontroller mounted on a smart phone, a tablet computer, a desktop computer, or a cloud server. The control module may include, but is not limited to, a processor 130 and a memory 131. Those skilled in the art will appreciate that Figure 4 This is only an example of the control module 13 and does not constitute a limitation on the control module 13 , which may include more or fewer components than shown in the figure, or a combination of certain components, or different components, for example, may also include input and output devices, network access devices, etc.

[0145] The processor 130 may be a central processing unit (CPU), or other general-purpose processors, digital signal processors (DSP), application-specific integrated circuits (ASIC), field-programmable gate arrays (FPGA) or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components, etc. A general-purpose processor may be a microprocessor or any conventional processor, etc.

[0146] In some embodiments, the memory 131 may be an internal storage unit of the control module 13, such as a hard disk or memory of the control module 13. In other embodiments, the memory 131 may also be an external storage device of the control module 13, such as a plug-in hard disk, a smart media card (SMC), a secure digital (SD) card, a flash card, etc. equipped on the control module 13. Further, the memory 131 may also include both an internal storage unit of the control module 13 and an external storage device. The memory 131 is used to store an operating system, an application program, a boot loader (BootLoader), data, and other programs, such as the program code of the computer program. The memory 131 may also be used to temporarily store data that has been output or is to be output.

[0147] In addition, an embodiment of the present application further provides a computer-readable storage medium, wherein the computer-readable storage medium stores a computer program, and when the computer program is executed by a processor, the steps in any of the above method embodiments are implemented.

[0148] An embodiment of the present application provides a computer program product. When the computer program product runs on a control module, the control module implements the steps in the above-mentioned method embodiments when executed.

[0149] In several embodiments provided in the present application, it is understood that each box in the flow chart or block diagram can represent a module, a program segment or a part of a code, and the module, a program segment or a part of a code contains one or more executable instructions for realizing the specified logical function. It should also be noted that in some alternative implementations, the functions marked in the box can also occur in a different order from that marked in the accompanying drawings. For example, two consecutive boxes can actually be executed substantially in parallel, and they can sometimes be executed in the opposite order, depending on the functions involved.

[0150] If the function is implemented in the form of a software function module and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on this understanding, the technical solution of the present application can essentially or in other words, the part that contributes to the prior art or the part of the technical solution can be embodied in the form of a software product. The computer software product is stored in a storage medium and includes several instructions for a control module to execute all or part of the steps of the method described in each embodiment of the present application. The aforementioned storage medium includes: U disk, mobile hard disk, read-only memory (ROM, Read-Only Memory), random access memory (RAM, Random Access Memory), disk or optical disk and other media that can store program codes.

[0151] The specific embodiments described above further describe the purpose, technical solutions and beneficial effects of the present application in detail. It should be understood that the above description is only a specific embodiment of the present application and is not intended to limit the scope of protection of the present application. It is particularly pointed out that for those skilled in the art, any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application should be included in the scope of protection of the present application.

Claims

1. A microwave focused thermal therapy system for tumor treatment, characterized in that: include: A microwave transmitting module, wherein the microwave transmitting module is arranged toward the tumor tissue to be treated, and a transmitting port of the microwave transmitting module is used to transmit microwaves toward the tumor tissue, and the microwaves are used to heat the tumor tissue; An energy-focusing waveguide module, which is arranged in front of the emission port and is used to focus the microwaves on the tumor area; A cooling module, the cooling module is arranged around the launch port to form a cooling channel around the launch port; An information acquisition module, the information acquisition module is used to acquire sensing information and image information of the tumor tissue; a control module, the control module being in communication with the microwave transmitting module, the cooling module and the information acquisition module respectively, and the control module being used to generate microwave frequency information, temperature adjustment information and a target area according to the sensing information and image information sent by the information acquisition module before the microwave transmitting module transmits microwaves to the tumor tissue, wherein the target area is located in the tumor tissue; The control module is used to control the microwave transmitting module to transmit the microwave toward the target area according to the microwave frequency information, and to adjust the power of the cooling module according to the temperature adjustment information.

2. The system according to claim 1, characterized in that The sensing information includes temperature information and pressure information, and the image information includes tissue image information and medical imaging information; the information acquisition module includes: A temperature sensing component, wherein the temperature sensing component is used to monitor the temperature information of the tumor tissue; A pressure sensing component, wherein the pressure sensing component is used to monitor pressure information of the tumor tissue; An image acquisition component, the image acquisition component is arranged toward the tumor tissue, and the image acquisition component is used to acquire tissue image information of the tumor tissue; An image acquisition component is arranged toward the tumor tissue, and is used to acquire medical image information corresponding to the tumor tissue; wherein the image acquisition component at least includes an ultrasound device and / or a magnetic resonance imaging device.

3. The system according to claim 2, characterized in that The control module obtains tumor boundary information and tumor morphology information based on the tissue image information and the medical imaging information, so as to determine the target area in the tumor tissue based on the tumor boundary information, the tumor morphology information and the pressure information; the control module also generates the microwave frequency information based on the area information, the tumor morphology information and the temperature information of the target area; the control module also determines the temperature change information after the microwave is emitted based on the microwave frequency information, the temperature information and the tumor morphology information, so as to generate the temperature adjustment information based on the temperature change information and the preset target temperature.

4. The system according to claim 2, characterized in that The control module also obtains the tissue thermal conductivity value, dielectric constant and morphological factor corresponding to the tumor tissue according to the tissue image information and tumor morphological information; the control module generates a thermal conductivity correction coefficient according to the tissue thermal conductivity value; the control module generates the microwave frequency information according to the preset target temperature, thermal conductivity correction coefficient, temperature information, dielectric constant, morphological factor, area information of the target area and a preset basic frequency, wherein the basic frequency is the lowest starting frequency corresponding to microwave focused thermal therapy; The expression of the microwave frequency information includes: ； Wherein, F is the value corresponding to the microwave frequency information, is the fundamental frequency, is the value corresponding to the area information, is the morphological factor, is the target temperature, is the value corresponding to the temperature information, is the dielectric constant, is the thermal conductivity correction coefficient, is the first adjustment coefficient, is the second adjustment coefficient.

5. The system according to claim 2, characterized in that The temperature sensing component is also used to monitor the peripheral temperature information of the surrounding tissue corresponding to the tumor tissue, and the cooling module is also arranged toward the surrounding tissue; Among them, the control module receives the peripheral temperature information sent by the temperature sensing component. If the peripheral temperature information is greater than or equal to a preset maximum temperature, the control module controls the cooling module to adjust the temperature of the peripheral tissue until the peripheral temperature information is less than the maximum temperature.

6. The system according to claim 1, characterized in that The microwave transmitting module comprises: A solid-state microwave generator, wherein the solid-state microwave generator is used to generate the microwaves; A frequency control circuit, the frequency control circuit is electrically connected to the solid-state microwave generator, and the frequency control circuit is also in communication connection with the control module, and is used to adjust the frequency of the solid-state microwave generator according to the microwave frequency information sent by the control module; A power amplifier, the power amplifier is electrically connected to the solid-state microwave generator and is used to increase the power of the microwave; A transmitting antenna, the transmitting antenna is used to transmit the amplified microwave to the target tissue through the energy focusing waveguide module; wherein the transmitting antenna includes any one of a horn antenna or a patch antenna; An antenna matching network is electrically connected to the solid-state microwave generator and the transmitting antenna, and is used to obtain impedance information of the solid-state microwave generator, so as to adjust the impedance of the transmitting antenna according to the impedance information, and ensure that the impedance of the transmitting antenna matches the impedance of the solid-state microwave generator.

7. The system according to claim 1, characterized in that The energy focusing waveguide module comprises: A conical waveguide, wherein the conical waveguide comprises a circular inlet and a conical outlet, wherein the circular inlet is connected to the emission port, and the conical outlet is arranged toward the target tissue, and when the microwave enters the circular inlet, a waveguide channel is formed inside the conical waveguide; A dielectric mirror, which is located in the middle of the waveguide channel and / or close to the conical outlet and is used to focus the microwave; Wherein, the tapered waveguide is made of polytetrafluoroethylene material or ferrite material.

8. The system according to claim 1, characterized in that The system further comprises: A rotating module, the rotating module is connected to the microwave transmitting module and is used to control the direction of the transmitting port of the microwave transmitting module; Among them, the rotation module is also communicatively connected to the control module, and the control module is used to generate adjustment position information according to the position information corresponding to the target area and the position information corresponding to the microwave transmission module, so as to control the rotation module to rotate according to the adjustment position information so that the transmission port faces the target area.

9. A method for microwave focused thermal therapy for tumor treatment, characterized in that: A control module applied to a microwave focused thermal therapy system for tumor treatment according to any one of claims 1 to 8; the method comprising: Before the microwave transmitting module transmits microwaves to the tumor tissue, the sensing information and image information sent by the information collecting module are obtained; generating microwave frequency information, temperature adjustment information and a target area according to the sensing information, wherein the target area is located in the tumor tissue; Control the microwave emission module to emit microwaves toward the target area according to the microwave frequency information; The power of the cooling module is adjusted according to the temperature adjustment information to complete the microwave focused heat therapy for the tumor tissue.

10. A microwave focused thermal therapy device for tumor treatment, characterized in that: A control module for a microwave focused thermal therapy system for tumor treatment as claimed in any one of claims 1 to 8; the device comprises: An information acquisition unit, used for acquiring the sensing information and image information sent by the information acquisition module before the microwave emission module emits microwaves to the tumor tissue; an information generating unit, configured to generate microwave frequency information, temperature adjustment information and a target area according to the sensing information, wherein the target area is located in the tumor tissue; A microwave transmitting unit, used for controlling the microwave transmitting module to transmit the microwave toward the target area according to the microwave frequency information; The thermal therapy completion unit is used to adjust the power of the cooling module according to the temperature adjustment information to complete the microwave focused thermal therapy of the tumor tissue.

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