Preparation method and application of cold-dampness dispelling massage cream

Abstract

The preparation method comprises the following steps: S1, preparing 150 parts by weight of folium artemisiae argyi, 100 parts by weight of dried ginger, 50 parts by weight of Chinese prickly ash, 50 parts by weight of cinnamon and 100 parts by weight of radix angelicae pubescentis into an extract (phase A); s2, crushing and sieving matrix raw materials, and fully mixing vaseline and olive oil to prepare an oil phase (phase B); the matrix raw materials comprise 250 parts of fresh ginger, and the raw materials are juiced and blended with the medicines in the step S1; s3, fully swelling hydroxypropyl methyl cellulose (HPMC) and sodium hyaluronate in water to obtain a water phase (phase C); s4, adding the extract and the water phase into the oil phase at the same time, heating, softening and uniformly mixing to form ointment; and S5, the ointment is heated and softened, and the heated and softened ointment is packaged, sealed and stored. The massage cream prepared by the invention has the effects of dispelling cold-dampness and improving cold-dampness constitution, and is convenient to use and easy to carry and store.

Description

Technical Field

[0001] The invention belongs to the technical field of production technology of traditional Chinese medicine compositions, and relates to a preparation method and application of a massage cream for removing cold and dampness. Background Art

[0002] Cold and dampness is an important pathological state in traditional Chinese medicine theory and is considered to be one of the root causes of many diseases. The basic theory of traditional Chinese medicine emphasizes that the human body is an organic whole, and the organs, meridians, qi and blood are interconnected. When cold and dampness invade the human body, it will affect the circulation of qi and blood and the function of the organs, leading to the occurrence of various diseases.

[0003] There are many discussions on cold and dampness in the Yellow Emperor's Classic of Internal Medicine. For example, Suwen · Tiaojinglun mentions that "people who are affected by cold and dampness have skin that does not contract, muscles that are tight, blood that cries, and defensive qi that leaves, so they are called weak", which explains that after the cold and dampness invade the human body, it will lead to pathological changes in the skin and muscles and abnormalities in qi and blood. Suwen · Bilun records that "the three qi of wind, cold and dampness come together and form bi", pointing out that cold and dampness can cause bi syndrome, leading to symptoms such as joint pain and limb numbness. These classic discussions provide a theoretical basis for us to understand cold and damp constitution and related diseases.

[0004] In contemporary society, due to the influence of various factors such as living environment, eating habits and lifestyle, the number of people with cold and damp constitution is gradually increasing. From the perspective of living environment, long-term exposure to damp and cold environment, such as living in a basement and frequent contact with cold water, can easily invade the human body. In terms of eating habits, excessive consumption of raw and cold food, such as drinking a lot of iced drinks and eating sashimi, can damage the spleen and stomach yang energy, leading to endogenous cold and dampness. In addition, people in modern society have a fast pace of life and high work pressure. Long-term mental stress and fatigue can also affect the body's yang energy, reducing the body's ability to resist cold and dampness.

[0005] People with cold and damp constitution are prone to a series of clinical symptoms. In terms of joints, cold and dampness stagnate in joints, which can cause joint pain, swelling, and difficulty in flexion and extension, which are common in diseases such as rheumatoid arthritis and osteoarthritis. In the digestive system, cold and dampness can affect the spleen and stomach's transportation and transformation functions, resulting in symptoms such as indigestion, loss of appetite, abdominal distension, and diarrhea. In the cardiovascular system, cold and dampness can block the heart yang, leading to symptoms such as palpitations, chest tightness, and chest pain. These symptoms not only affect the patient's physical health, but also reduce the patient's quality of life.

[0006] Clinical studies in recent years have further confirmed the correlation between cold-damp constitution and a variety of diseases. For example, a clinical study on patients with rheumatoid arthritis found that most patients had the characteristics of cold-damp constitution. By adjusting the cold-damp constitution of patients, such as taking Chinese medicine internally or externally, the patients' conditions have improved to a certain extent. For another example, in the study of some digestive system diseases, it was found that cold-dampness trapped in the spleen is one of the important factors leading to the occurrence and development of the disease. The treatment method of warming yang and removing dampness can effectively relieve the symptoms of patients.

[0007] In summary, cold and damp constitution is more common in contemporary society and is closely related to the occurrence and development of various diseases. Therefore, improving cold and damp constitution is of great significance for the prevention and treatment of related diseases. At present, there are many kinds of products for removing cold and dampness on the market, but massage cream is relatively rare and may be insufficient in composition and efficacy. Therefore, it is of great practical significance to develop an efficient, safe and easy-to-use massage cream for removing cold and dampness. Summary of the invention

[0008] In view of this, the present invention provides a preparation method of a massage cream for removing cold and dampness, so as to achieve the purpose of effectively removing cold and dampness and improving cold and dampness constitution.

[0009] To achieve the above object, the present invention provides the following technical solutions:

[0010] A method for preparing a massage cream for removing cold and dampness, comprising the following steps by weight:

[0011] S1. Prepare an extract (phase A) from 150 parts of wormwood leaves, 100 parts of dried ginger, 50 parts of prickly ash, 50 parts of cinnamon bark and 100 parts of angelica dahurica.

[0012] S2, crushing and sieving the matrix raw materials, fully mixing vaseline and olive oil to prepare an oil phase (phase B); the matrix raw materials include 250 parts of ginger, squeezed juice, and blended with the drugs in step S1;

[0013] S3, fully dissolving hydroxypropyl methylcellulose (HPMC) and sodium hyaluronate in water to obtain an aqueous phase (phase C);

[0014] S4, adding the extract and the water phase into the oil phase at the same time, softening and mixing evenly to form an ointment;

[0015] S5, heating and softening the ointment, and packaging the heated and softened ointment and sealing it for storage.

[0016] Furthermore, in step S5, the heated and softened ointment is packaged in a light-proof plastic bottle or a glass bottle.

[0017] The present invention also provides application of the prepared massage cream for removing cold and dampness in preparing medicine for removing cold and dampness.

[0018] Properties and efficacy of the Chinese medicine used:

[0019] Artemisia argyi is bitter, pungent and warm in nature and flavor. It enters the liver, spleen and kidney meridians. It has the effects of warming the meridians and dispelling cold, removing dampness and relieving itching, stopping bleeding and stabilizing pregnancy. Its pungent and warm nature can dispel cold and dampness and warm the meridians and blood. The Compendium of Materia Medica records that Artemisia argyi can "warm the middle, expel cold and remove dampness". Modern clinical studies have shown that Artemisia argyi contains volatile oils, flavonoids and other ingredients. The main ingredients in volatile oils, such as eucalyptol and camphor, have antibacterial, anti-inflammatory and analgesic effects. They can effectively relieve symptoms such as joint pain and skin itching caused by cold and dampness, and have a good regulating effect on the poor blood circulation caused by cold and dampness.

[0020] Dried ginger is hot in nature and pungent in taste. It enters the spleen, stomach, kidney, heart and lung meridians. Dried ginger can warm the middle and dispel cold, restore yang and dredge meridians, and dry dampness and eliminate phlegm. It is hot in nature and pungent in taste. It is an important medicine for warming the middle and dispelling cold. "Shennong's Herbal Materia Medica" records that dried ginger "treats chest fullness, cough, reverse breathing, warms the middle, stops bleeding, sweats, expels wind and rheumatism, and diarrhea". Modern research has found that dried ginger contains gingerol and other ingredients, which have anti-inflammatory, antioxidant, and gastrointestinal motility-promoting effects. It has a significant improvement effect on the symptoms of spleen and stomach dysfunction caused by cold and dampness in the spleen, such as indigestion, loss of appetite, abdominal distension, diarrhea, etc., and can effectively enhance the spleen and stomach yang and dispel cold and dampness.

[0021] Zanthoxylum bungeanum is pungent and hot in nature, and enters the spleen, stomach, and kidney meridians. Zanthoxylum bungeanum has the effects of warming the middle and relieving pain, killing insects and relieving itching. The warm nature of Zanthoxylum bungeanum can be used to dispel cold and dampness, especially for digestive system symptoms caused by cold and dampness, such as abdominal pain, diarrhea, abdominal distension, etc. It contains volatile oils, alkaloids and other ingredients. Modern clinical studies have shown that Zanthoxylum bungeanum volatile oil has antibacterial, anti-inflammatory, analgesic and other effects, can enhance the body's immunity, resist the invasion of cold and dampness, and at the same time has a direct effect on removing cold and dampness in the gastrointestinal tract.

[0022] Cinnamon is pungent and sweet, and is very hot in nature. It enters the kidney, spleen, heart, and liver meridians. Cinnamon can replenish fire and yang, dispel cold and relieve pain, warm and dredge the meridians, and guide fire back to its origin. Its hot nature can strongly dispel cold and dampness, and has significant therapeutic effects on cardiovascular system symptoms such as palpitations and chest tightness caused by cold and dampness blocking the heart yang, as well as joint pain and flexion and extension difficulties caused by cold and dampness stagnation in joints. "Compendium of Materia Medica" records that cinnamon "treats cold arthralgia, wind arthralgia, yin carbuncle, liushui, and amenorrhea." Modern research shows that cinnamon contains volatile oils, cinnamaldehyde and other ingredients, which have the effects of dilating blood vessels, promoting blood circulation, anti-inflammatory, analgesic, etc., which helps to improve the circulation of qi and blood in patients with cold and damp constitution and restore the normal function of internal organs.

[0023] Duhuo tastes pungent and bitter, is slightly warm in nature, and enters the kidney and bladder meridians. Duhuo has the effects of dispelling wind and dampness, relieving numbness and relieving pain. Duhuo is often used for wind-cold-dampness arthralgia, waist and knee pain and other symptoms. Its pungent, dispersing, bitter and dry nature can effectively dispel cold and dampness, and has a good therapeutic effect on symptoms such as joint pain and limb numbness caused by cold and dampness. Modern research shows that Duhuo contains volatile oils, coumarins and other ingredients, which have anti-inflammatory, analgesic, sedative and other effects, can relieve the invasion of cold and dampness on joints and muscles, and restore the normal activity function of joints.

[0024] The beneficial effects of the present invention are:

[0025] The wormwood leaf, dried ginger, pepper, cinnamon and angelica root in the massage cream Chinese medicine formula all have the effects of warming yang, dispelling cold, removing dampness and relieving pain. They are compatible with each other and have significant synergistic effects. For example, when cinnamon is paired with dried ginger, the fire-replenishing and yang-boosting effects of cinnamon and the warming and cold-dispelling effects of dried ginger reinforce each other, and the symptoms of cold and dampness blocking the spleen are more significantly improved; wormwood leaf and angelica root cooperate to promote each other in dispelling wind and dampness, relieving numbness and relieving pain, and can better relieve symptoms such as joint pain and limb numbness caused by cold and dampness. At the same time, the pharmacological effects of these drugs such as anti-inflammatory and analgesia also overlap with each other, thereby more effectively improving the clinical symptoms of patients with cold and damp constitution.

[0026] The Chinese medicine formula of the massage cream has effects on multiple systemic symptoms related to cold and damp constitution. For the joint system, it can relieve symptoms such as joint pain, swelling, and difficulty in flexion and extension; for the digestive system, it can improve symptoms such as indigestion, loss of appetite, abdominal distension, and diarrhea; for the cardiovascular system, it can relieve symptoms such as palpitations, chest tightness, and chest pain. This multi-system effect makes the massage cream suitable for a variety of diseases caused by cold and damp constitution, and has broad application prospects.

[0027] As a transdermal drug delivery method, massage cream avoids possible gastrointestinal irritation and first-pass effect of oral drugs on the liver, and has relatively few toxic side effects. It can act directly on the affected area, reduce systemic drug distribution, and reduce the impact on other organs, making it particularly suitable for local treatment. Massage cream can be made at home, is easy to use, and is easy to carry and store. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings in the following description are only embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying creative work.

[0029] Figure 1 The present invention provides a flow chart of a method for preparing a massage cream for removing cold and dampness according to an embodiment of the present invention. DETAILED DESCRIPTION

[0030] The technical scheme in the embodiment of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiment of the present invention. It should be noted that the following detailed description is illustrative and is intended to provide further explanation of the present invention. Unless otherwise specified, all technical and scientific terms used in the present invention have the same meanings as those generally understood by ordinary technicians in the technical field to which the present invention belongs.

[0031] like Figure 1 As shown, a method for preparing a massage cream for removing cold and dampness comprises the following steps:

[0032] S1. Prepare an extract (phase A) with 150 g of mugwort leaves, 100 g of dried ginger, 50 g of pepper, 50 g of cinnamon bark and 100 g of angelica dahurica.

[0033] S2, crushing and sieving the matrix raw materials, fully mixing vaseline and olive oil to prepare an oil phase (phase B); the matrix raw materials include 250g ginger, squeezed juice, and blended with the drugs in step S1;

[0034] S3, fully dissolving hydroxypropyl methylcellulose (HPMC) and sodium hyaluronate in water to obtain an aqueous phase (phase C);

[0035] S4, adding the extract prepared in step S1 and the aqueous phase prepared in step S3 to the oil phase prepared in step S2 at the same time, softening and mixing evenly to form an ointment;

[0036] S5, heating and softening the ointment, and packaging the heated and softened ointment in a light-proof plastic bottle or glass bottle and sealing it for storage.

[0037] The present invention also provides application of the prepared massage cream for removing cold and dampness in preparing medicine for removing cold and dampness.

[0038] The transdermal administration of massage cream is more stable than oral medication and directly enters the blood, avoiding the first-pass effect of the liver and irritation to the intestines. It acts directly on the affected area, which can enhance the efficacy and reduce the impact on other organs. The drug with the effect of removing dampness and dispersing cold is prepared into a massage cream, which has the functions of being easy to carry and use, and can better achieve the effect of dispelling dampness in the human body.

[0039] The above is a detailed introduction to the preparation method of a massage cream for removing cold and dampness provided by the present invention. Specific examples are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only applicable to help understand the method of the present invention and its core idea. It should be pointed out that for ordinary technicians in this technical field, without departing from the principle of the present invention, the present invention can also be improved and modified in a number of ways, and these improvements and modifications also fall within the scope of protection of the claims of the present invention.

Claims

1. A method for preparing a massage cream for removing cold and dampness, characterized in that: By weight, the method comprises the following steps: S1. Prepare an extract (phase A) from 150 parts of wormwood leaves, 100 parts of dried ginger, 50 parts of prickly ash, 50 parts of cinnamon bark and 100 parts of angelica dahurica. S2, crushing and sieving the matrix raw materials, fully mixing vaseline and olive oil to prepare an oil phase (phase B); the matrix raw materials include 250 parts of ginger, squeezed juice, and blended with the drugs in step S1; S3, fully dissolving hydroxypropyl methylcellulose (HPMC) and sodium hyaluronate in water to obtain an aqueous phase (phase C); S4, adding the extract and the water phase into the oil phase at the same time, softening and mixing evenly to form an ointment; S5, heating and softening the ointment, and packaging the heated and softened ointment and sealing it for storage.

2. The method for preparing the massage cream for removing cold and dampness according to claim 1, characterized in that: In step S5, the heated and softened ointment is packaged in a light-proof plastic bottle or a glass bottle.

3. Use of the cold-dampness-removing massage cream obtained according to the preparation of the cold-dampness-removing massage cream according to claim 1 or 2 in the preparation of a medicine for removing cold-dampness.

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