Novel bladder perfusion device

Abstract

The invention relates to the technical field of medical instruments, in particular to a novel bladder perfusion device which comprises a perfusion catheter, an injector, a first connecting portion and a second connecting portion. The injection needle cylinder is detachably connected with the medicine extraction needle, the piston is arranged in the injection needle cylinder in a pluggable mode, the interface module is arranged at the front end of the injection needle cylinder, and the interface module is made of a flexible silica gel material with certain flexibility and flexibility so as to ensure that the interface module can be tightly connected with the medicine extraction needle or the tail end of a catheter. A locking ring is arranged on the outer wall of the interface module; the first connecting part is arranged on the inner wall of a needle tube of the medicine extraction needle and is detachably matched with the locking ring so as to realize seamless connection between the needle tube and the interface module; the second connecting part is arranged on the inner wall of the interface end of the tube body of the perfusion catheter and is detachably matched with the locking ring, so that seamless connection between the perfusion catheter and the interface module is realized.

Description

Technical Field

[0001] The invention belongs to the technical field of medical devices, and in particular relates to a novel bladder instillation device. Background Art

[0002] Bladder cancer is one of the most common malignant tumors in the urinary system, especially in the elderly. For patients with non-muscle-invasive bladder cancer, intravesical instillation therapy is a common and effective treatment method after bladder cancer surgery. Injecting drugs directly into the bladder through a catheter can kill residual tumors after surgery, prevent tumor recurrence, and have little systemic toxicity and side effects. The success of intravesical instillation therapy depends largely on the design and use of the instillation device.

[0003] At present, bladder instillation devices include standard double-lumen catheters (F16), 50ml syringes and needles, and bladder irrigators. However, these tools have some significant defects in actual use. One of the main problems is the mismatch between the diameter of the end aperture of the catheter and the diameter of the syringe, which requires medical staff to transfer the drug solution to the bladder irrigator before instillation, which not only increases the complexity of the operation, but also may cause the instability of the interface, the risk of drug leakage, and affect the instillation treatment operation. Specifically, at present, the common bladder instillation devices on the market usually use a standard double-lumen catheter (F16), a 50ml syringe and a bladder irrigator in combination. This type of catheter is usually made of medical silicone or latex material, has a certain degree of flexibility, and is easy to insert into the patient's bladder. However, the end aperture design of this catheter often cannot fully match the outlet diameter of the standard syringe, resulting in the need to transfer the drug solution to the bladder irrigator before use to ensure a smooth connection. The adjustment method is usually: the medical staff inhales the drug solution through a 50ml syringe, transfers it to the bladder irrigator, connects the catheter, and injects it into the patient's bladder.

[0004] In summary, the existing bladder instillation devices have the following disadvantages: Poor interface matching: The end aperture of the current catheter does not match the diameter of the standard syringe. When dispensing medicine, medical staff need to first use a 50ml syringe to absorb the liquid medicine in the ampoule, then transfer it to a bladder irrigator (usually 70ml), and then connect the catheter through the bladder irrigator, insert the catheter into the patient's bladder, and complete the injection. This operation is cumbersome and time-consuming, increasing the complexity of clinical operations.

[0005] Unstable connection: The ends of the bladder irrigator and the catheter are not naturally anastomosed, and the outlet of the bladder irrigator is fixed by the elastic expansion of the end of the catheter. During the process of injecting drugs into the bladder, if the speed is too fast or the connection is not tight, the interface between the catheter and the bladder irrigator is prone to loosening or falling off, causing drug leakage, affecting the infusion operation and treatment effect. It may also contaminate the treatment area and even cause harm to medical staff and patients, posing safety risks and increasing medical costs.

[0006] Poor patient experience: Due to the complicated operation process and unstable connection, the operation time is prolonged, which can easily lead to contamination and cause urinary tract infection in patients, reducing the tolerance and satisfaction of treatment.

[0007] High dependence on operating technology: Existing technical solutions have high requirements on the experience and skills of operators. Differences in operating levels among different operators may lead to differences in perfusion efficiency and effect, increasing the subjectivity and uncertainty of the operation.

[0008] 201820856724.X discloses a disposable silicone catheter for bladder infusion, which includes: a tube body, an infusion inlet at the upper end of the tube body, a front connector of the catheter designed as a Luer cone connector, a fixed wing, a length scale, and a diameter mark at the bottom, and a side outlet hole and a straight outlet hole at the lower end of the tube body. The tube wall at the lower end of the tube body is blunt and obliquely designed from outside to inside. The scale mark 7 can indicate the insertion depth. When the device is implemented, the diameter of the catheter is relatively thin, and the hardness meets the requirements for insertion into the bladder. The blunt design of the head end can avoid excessive stimulation of the urethra during catheterization, and the scale mark can avoid excessive insertion. The setting of the fixed wing is conducive to the placement and fixation of the catheter. It can be seen from the figure that it is difficult to connect the head of the infusion inlet of the front end of the infusion catheter tightly with the syringe.

[0009] The Second Affiliated Hospital of the Army Medical University of the Chinese People's Liberation Army disclosed a bladder instillation device in 202410071818.6, including a syringe, a sealing connector and a catheter. The syringe includes an injection syringe, a piston and a hollow needle nipple arranged on one end of the injection syringe. The outlet end of the catheter is sleeved on the hollow needle nipple. The sealing connector comprises an upper pressure syringe sleeve and a lower pressure syringe sleeve, both of which are semicircular sleeves, one end of which is provided with a semicircular baffle, an upper pressure catheter sleeve is provided on the semicircular baffle at one end of the upper pressure syringe sleeve, and a lower pressure catheter sleeve is provided on the semicircular baffle 23 at one end of the lower pressure syringe sleeve, the lengths of the upper pressure catheter sleeve and the lower pressure catheter sleeve are both greater than the length of the empty needle nipple, and one side of the upper pressure syringe sleeve and the lower pressure syringe sleeve are connected by a hinge. When in use, the outlet end of the catheter is sleeved on the empty needle nipple and placed on the lower pressure catheter sleeve, and then the upper pressure syringe sleeve is rotated to make the upper and lower pressure syringe sleeves buckled on the injection syringe, and the upper pressure catheter sleeve and the lower pressure catheter sleeve will be pressed on the catheter, so that the catheter and the empty needle nipple are completely fitted and sealed, effectively avoiding the overflow of chemotherapy drugs from the connection point, and ensuring that the drugs enter the bladder according to the precise dosage.

[0010] As can be seen from the above, existing bladder instillation devices need to be provided with a drug extraction channel and an instillation channel respectively, and multiple connections need to be designed for this purpose. The interfaces are prone to loosening or falling off, resulting in drug leakage and affecting the bladder instillation operation. Summary of the invention

[0011] The technical problem to be solved by the present invention is to provide a novel bladder instillation device; the technical solution of the present invention comprises an instillation catheter, a syringe, a first connecting part and a second connecting part, The syringe comprises a medicine extraction needle, a syringe barrel detachably connected to the medicine extraction needle, a piston pluggable in the syringe barrel, and an interface module arranged on the front end of the syringe barrel. The interface module is made of a flexible silicone material with certain elasticity and flexibility to ensure a tight connection with the medicine extraction needle or the end of the catheter. A locking ring is arranged on the outer wall of the interface module. The first connecting portion is arranged on the inner wall of the needle tube of the medicine extraction needle and is detachably matched with the locking ring to achieve seamless connection between the needle tube and the interface module; The second connecting portion is arranged on the inner wall of the interface end of the tube body of the irrigation catheter and is detachably matched with the locking ring to achieve seamless connection between the irrigation catheter and the interface module; The device switches between working modes of drug extraction mode and infusion mode; Medicine extraction mode: the first connection part of the medicine extraction needle cooperates with the locking ring on the outer wall of the interface module, the needle tube of the medicine extraction needle is tightly sleeved on the outer wall of the interface module on the front end of the injection syringe, and the injection liquid is extracted from the medicine extraction needle into the injection syringe of the syringe by piston movement, and then the first connection part is disassembled; the medicine extraction needle, the interface module and the injection syringe form a medicine extraction channel; Infusion mode: The second connection part of the infusion catheter cooperates with the locking ring on the outer wall of the interface module, and the interface end of the infusion catheter is tightly sleeved on the outer wall of the interface module on the front end of the injection syringe, and the injection liquid is introduced into the infusion catheter and then into the target to be infused through the movement of the piston. The syringe, the interface module and the infusion catheter form an infusion channel; The medicine extraction channel and the perfusion channel are coaxially arranged.

[0012] Furthermore, the interface module is shaped as a columnar structure that matches the inner cavity of the perfusion catheter; the locking ring includes a plurality of protruding structures arranged on the outer wall of the interface module, and the protruding structure includes a limiting plate connected to the outer wall of the interface module, and an end of the limiting plate that is not connected to the interface module extends toward the injection syringe to form an arc-shaped fixing plate.

[0013] Furthermore, the first connecting part / the second connecting part is a plurality of hollow grooves arranged on the inner wall of the interface end of the tube body of the medicine withdrawal needle / the perfusion catheter, the cross-sectional shape of the hollow groove matches the locking ring, the maximum arc length of a single hollow groove is at least twice the maximum arc length of the limit plate, and there is no through connection between two adjacent hollow grooves.

[0014] Furthermore, the end of the same side of each of the hollow grooves extends toward the end surface of the interface end to form a guide groove for the locking ring to enter, and the shape and size of the guide groove match the limiting plate.

[0015] Furthermore, the locking ring is made of a high-strength polymer material and the tightness of the interface can be adjusted by rotation.

[0016] Furthermore, the protruding structure of the locking ring is fixed in the hollow groove at one end away from the guide groove and maintains its fixed state, which is a locked state; the protruding structure is rotated out of the hollow groove toward one end of the guide groove and pulled out of the hollow groove to be an unlocked state.

[0017] Furthermore, the first connecting portion and the medicine extraction needle are integrally formed.

[0018] Furthermore, the second connecting portion is integrally formed with the tube body of the perfusion catheter.

[0019] Furthermore, the perfusion catheter is a single-lumen catheter.

[0020] Furthermore, the inner diameter of the input section of the irrigation catheter is smaller than the inner diameter of the output end of the irrigation catheter.

[0021] Furthermore, a one-way valve for preventing backflow is provided on one side of the inner cavity of the input end of the perfusion catheter close to the input section.

[0022] Compared with existing bladder instillation techniques, 1. A new type of bladder infusion device of the present invention has significant advantages in terms of interface matching and connection stability. In the prior art, a common 50ml syringe is configured with liquid medicine and then transferred to a bladder irrigator, and then connected to a common urinary catheter, which not only increases the complexity of the operation, but also leads to unstable interface connection, and there is a risk of falling off and drug leakage. The present invention realizes a seamless connection between the urinary catheter and the syringe by using a flexible silicone material for the interface module on the front end of the injection syringe, and further enhances the firmness of the interface through an adjustable locking ring, which significantly improves the safety and efficiency of the infusion process.

[0023] 2. During bladder instillation, the stability of the interface is the key to ensuring smooth operation. To this end, the present invention designs an adjustable locking ring at the interface, which can further fix the connection between the catheter and the syringe by rotating the locking ring to prevent the interface from loosening or falling off during the instillation process. This design can enhance the stability of the connection, directly improve the safety and efficiency of bladder instillation operations, and enhance the patient's treatment experience.

[0024] After using the locking ring, the connection security between the syringe and the catheter is significantly improved, and the pull-out force (the ability of the connection interface to remain stable when subjected to external force) is improved compared to the traditional method.

[0025] 3. The inner diameter of the input section of the infusion catheter in a novel bladder infusion device of the present invention is smaller than the inner diameter of the output end in the bladder. The thin inner diameter of the input section avoids over-rapid infusion, reduces the drug residue in the thick pipe, and avoids the loss of effective therapeutic drug dosage; in addition, the output end inner diameter is designed to be larger than the input section, which can also effectively avoid the thin drug solution water column from impacting the bladder wall and reduce the patient's discomfort.

[0026] 4. The inner cavity of the input end of the infusion catheter of the present invention is provided with an anti-backflow one-way valve, which can effectively prevent residual urine from overflowing along the catheter due to various reasons such as patient tension, involuntary bladder contraction, etc. after the catheter is placed in the patient's body, and at the same time separate the inner cavity of the catheter from the surrounding environment to avoid patient infection. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] By reading the detailed description of the preferred embodiments below, various other advantages and benefits will become clear to those skilled in the art. The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings: Figure 1 It is a schematic diagram of an explosion of a novel bladder instillation device of the present invention; Figure 2 Schematic diagram of the structure of the first connecting part / second connecting part in a novel bladder instillation device of the present invention, (a) is an end view, and (b) is a perspective view from the end view; Figure 3 This is a schematic diagram of the connection between the first connecting part / the second connecting part and the locking ring of a novel bladder instillation device of the present invention; Figure 4 This is a work flow chart of a novel bladder instillation device of the present invention; Figure 5 A schematic diagram of a syringe opening a one-way valve of a novel bladder instillation device of the present invention; Figure 6 for Figure 1 Detail of the output end of the irrigation catheter at label A.

[0028] Reference numerals 1: Instillation catheter; 2: Syringe; 21: drug extraction needle; 22: injection syringe; 23: piston; 24: interface module; 3: first connecting part; 4: second connecting portion; 5: Locking ring; 51: limit plate; 52: fixed plate; 6: Guide groove; 7: One-way valve; 8: Card holder. DETAILED DESCRIPTION

[0029] The advantages and features of the present invention will become more apparent from the following description and claims.

[0030] In the prior art, the end of the catheter does not match the diameter of the 50ml syringe interface, and the therapeutic liquid needs to be transferred to the bladder irrigator to achieve the connection, which is not reliable. The present invention adopts a flexible silicone material to make the interface, designs a connection device with elasticity and adaptability, and realizes a seamless connection between the catheter and the syringe, which is simple and feasible. This design directly solves the problem of poor interface matching in the prior art and is the primary innovation of the present invention.

[0031] The method of bladder instillation is to insert a catheter into the patient's bladder, and then inject the drug solution into the patient's bladder through the catheter. It is generally suitable for postoperative treatment of bladder tumors. In general, if a patient has a bladder tumor, after the first electroresection surgery, he or she must follow up with bladder instillation chemotherapy or instillation immunotherapy. Common chemotherapy drugs include doxorubicin, epirubicin, gemcitabine, etc., and immunotherapy drugs commonly used are BCG. During the instillation, the patient empties the bladder in advance, then inserts the catheter used for instillation into the bladder, and then injects the diluted therapeutic drug directly into the patient's bladder through the catheter, removes the catheter, and asks the patient to hold his or her urine. After the operation, ask the patient to change his or her position in time so that the drug solution can fully contact the walls of the bladder, and the drug solution can be discharged after half an hour to two hours.

[0032] The present invention provides a novel bladder infusion device comprising an infusion catheter 1, a syringe 2, a first connecting part 3 and a second connecting part 4. The syringe 2 comprises a medicine extraction needle 21, an injection syringe 22 detachably connected to the medicine extraction needle 21, a piston 23 pluggable in the injection syringe 22, and an interface module 24 arranged on the front end of the injection syringe 22, wherein the interface module 24 is made of a flexible silicone material with certain elasticity and flexibility, and a locking ring 5 is arranged on the outer wall of the interface module 24; The first connecting portion 3 is disposed on the inner wall of the needle tube of the medicine extraction needle 21 and is detachably matched with the locking ring 5 to achieve seamless connection between the needle tube and the interface module 24; The second connecting portion 4 is disposed on the inner wall of the interface end of the tube body of the irrigation catheter 1 and is detachably matched with the locking ring 5 to achieve seamless connection between the irrigation catheter 1 and the interface module 24; The device switches between working modes of drug extraction mode and infusion mode; Medicine extraction mode: the first connection part 3 of the medicine extraction needle 21 cooperates with the locking ring 5 on the outer wall of the interface module 24, the needle tube of the medicine extraction needle 21 is tightly sleeved on the outer wall of the interface module 24 on the front end of the injection syringe 22, and the injection liquid is extracted from the medicine extraction needle 21 into the injection syringe 22 of the injector 2 by piston movement, and then the first connection part 3 is disassembled; the medicine extraction needle 21, the interface module 24 and the injection syringe 22 form a medicine extraction channel; Infusion mode: the second connection portion 4 of the infusion catheter 1 cooperates with the locking ring 5 on the outer wall of the interface module 24, the interface end of the infusion catheter 1 is tightly sleeved on the outer wall of the interface module 24 on the front end of the injection syringe 22, the injection liquid is introduced into the infusion catheter 1 by piston movement, and then the catheter 1 is pulled out, and the syringe, the interface module 24 and the infusion catheter 1 form an infusion channel; The medicine extraction channel and the perfusion channel are coaxially arranged.

[0033] The material selection and structural design of the flexible silicone interface is a major innovation of the present invention. The interface design of the present invention adopts a silicone material with elasticity and flexibility, and an annular protrusion structure is designed in the interface to ensure a close match with the end of the catheter and the needle. This design not only solves the problem of poor interface matching in the prior art, but also improves the stability of the connection, and has important innovation and practical value.

[0034] Specifically, the interface module 24 is shaped as a columnar structure that matches the inner cavity of the perfusion catheter 1; the locking ring 5 includes a plurality of raised structures arranged on the outer wall of the interface module 24, and the raised structure includes a limit plate 51 connected to the outer wall of the interface module 24, and an end of the limit plate 51 that is not connected to the interface module 24 extends toward the injection syringe 22 to form an arc-shaped fixing plate 52.

[0035] Specifically, the first connecting portion 3 / the second connecting portion 4 is a plurality of hollow grooves arranged on the inner wall of the interface end of the tube body of the medicine extraction needle 21 / the irrigation catheter 1, the cross-sectional shape of the hollow groove matches the locking ring 5, the maximum arc length of a single hollow groove is at least twice the maximum arc length of the limiting plate 51, and no two adjacent hollow grooves are connected through each other.

[0036] Specifically, the end of the same side of each hollow groove extends toward the end surface of the interface end to form a guide groove 6 for the locking ring 5 to enter, and the shape and size of the guide groove 6 match the limiting plate 51.

[0037] In the specific embodiment, the above contents are described in conjunction with the accompanying drawings. For ease of understanding, the axis of the interface module 24 is referred to as the first axis. Figure 1 -Attached Figure 2As shown, the limiting plates 51 in the several protruding structures are located in the same plane (the plane is parallel to the end face of the drug outlet end of the interface module 24) and are arranged around the periphery of the interface module 24, and the distance D from any point on the arc surface of the limiting plate 51 that is not connected to the interface module 24 to the first axis is equal; the arc-shaped fixing plate 52 is connected to the limiting plate 51, and the distance from any point on the outer wall of the arc-shaped fixing plate 52 to the first axis is D, and the distance from any point on the inner wall of the arc-shaped fixing plate 52 to the first axis is L; in this embodiment, only two protruding structures are drawn as a schematic, but it is not limited to two protruding structures.

[0038] Similarly, the inner wall of the interface end of the drug extraction needle 21 / the infusion catheter 1 is provided with a hollow groove matching the locking ring 5. Figure 2 Two hollow grooves are also drawn as a schematic, but it is not limited to two, and the specific number matches the number of raised structures; taking two as an example, in order to achieve the longest possible rotational connection, the maximum arc length of a single hollow groove is at least twice the maximum arc length of the limit plate 51, and in order to achieve limit rotation to the end, the two adjacent hollow grooves are not connected through.

[0039] Among them, in order to allow the interface module 24 to be first inserted into the inner cavity of the interface end of the tube body of the medicine withdrawal needle 21 / the perfusion catheter 1, the end of the same side of each of the hollow grooves extends toward the end face of the interface end to form a guide groove 6 for the locking ring 5 to enter, and the shape and size of the guide groove 6 match the limit plate 51. The limit plate 51 on the interface module 24 is aligned with the guide groove 6 and then inserted and rotated to achieve snap-in connection.

[0040] Specifically, the locking ring 5 is made of high-strength polymer material, and the tightness of the interface can be adjusted by rotation.

[0041] Specifically, the protruding structure of the locking ring 5 is fixed in the hollow groove at one end away from the guide groove 6 and maintains its fixed state, which is a locked state; the protruding structure is rotated out of the hollow groove toward one end of the guide groove 6 and pulled out of the hollow groove to be an unlocked state.

[0042] Specifically, the first connecting portion 3 and the medicine withdrawing needle 21 are integrally formed.

[0043] Specifically, the second connecting portion 4 is integrally formed with the tube body of the irrigation catheter 1. Figure 6 The output end of the perfusion catheter is evenly provided with three output ports (the ellipse shown by the dotted line is the output port provided on the back), that is, the angle formed by the midline of any two adjacent output ports and the midline of the perfusion catheter is 120°.

[0044] Specifically, the perfusion catheter 1 is a single-lumen catheter.

[0045] In the example, in addition to flexible silicone, other materials with good biocompatibility and elasticity, such as thermoplastic elastomer (TPE), polyurethane (PU), etc., can also be used to manufacture the interface module 24. These materials can also provide sufficient stretchability and flexibility to achieve seamless connection.

[0046] Instead of the fixing method of the locking ring 5, other mechanical fixing devices such as spring buckles, snap-on locking mechanisms, or even adjustable spiral connectors can be used. These alternatives can also ensure the stable connection between the catheter and the syringe 2 to prevent loosening or falling off during the infusion process.

[0047] In addition to the annular protrusion structure, the exterior of the interface module 24 can also be designed as a multi-stage gradual structure or a trapezoidal embedded groove, using designs of different shapes to enhance the friction and sealing between the irrigation catheter 1 and the interface module 24, thereby ensuring the stability of the connection.

[0048] Specifically, the inner diameter of the input section of the irrigation catheter 1 (the middle section of the irrigation catheter for liquid delivery) is smaller than the inner diameter of the output end of the irrigation catheter (the end located in the bladder).

[0049] Specifically, a one-way valve 7 for preventing backflow is provided on one side of the inner cavity of the input end of the perfusion catheter 1 near the input section (the end connected to the syringe 2). Before the syringe 2 is inserted into the input end of the perfusion catheter 1, the inner channel is isolated from the outside world. After the syringe 2 is inserted into the input end of the perfusion catheter 1, the one-way valve 7 is opened unidirectionally toward the inner cavity of the perfusion catheter 1. In a specific implementation, in order to ensure the connection stability between the syringe 2 and the perfusion catheter 1, after the two are connected, the outer wall of the input end of the perfusion catheter 1 can be wrapped and inserted into a C-type ferrule 8 to achieve further fixation (similar to the snap-fit ​​style of a press pump).

[0050] Combined with Figure 4 The method of use of the present invention is as follows: Step 1: When preparing to perform bladder instillation treatment on a patient who has reduced water intake and emptied his bladder in advance before instillation, the medical staff first uses the syringe 2 and needle of the present invention to prepare the treatment solution, and then removes the needle.

[0051] Step 2: Select an irrigation catheter 1 of appropriate specifications and insert it into the patient's bladder.

[0052] Step 3: Connect the new syringe 2 of the present invention to the irrigation catheter 1. Insert the end of the irrigation catheter 1 into the interface of the syringe 2, and use the elasticity of the flexible silicone interface module 24 to ensure seamless connection between the two. Then, rotate the locking ring 5 to further fix the interface to ensure the stability of the connection.

[0053] Step 4: Inject the treatment slowly and evenly into the bladder.

[0054] Step 5: After the infusion is completed, pull out the syringe 2 and the infusion catheter 1 together.

[0055] The embodiments of the present invention are described in detail above in conjunction with the accompanying drawings, but the present invention is not limited to the above embodiments. Even if various changes are made to the present invention, if these changes fall within the scope of the claims of the present invention and their equivalents, they still fall within the protection scope of the present invention.

Claims

1. A novel bladder instillation device, characterized in that: The invention comprises an irrigation catheter, a syringe, a first connecting part and a second connecting part, The syringe comprises a medicine extraction needle, a syringe barrel detachably connected to the medicine extraction needle, a piston pluggable in the syringe barrel, and an interface module arranged on the front end of the syringe barrel. The interface module is made of a flexible silicone material with certain elasticity and flexibility to ensure a tight connection with the medicine extraction needle or the end of the catheter. A locking ring is arranged on the outer wall of the interface module. The first connecting portion is arranged on the inner wall of the needle tube of the medicine extraction needle and is detachably matched with the locking ring to achieve seamless connection between the needle tube and the interface module; The second connecting portion is arranged on the inner wall of the interface end of the tube body of the irrigation catheter and is detachably matched with the locking ring to achieve seamless connection between the irrigation catheter and the interface module; The device switches between working modes of drug extraction mode and infusion mode; Medicine extraction mode: the first connection part of the medicine extraction needle cooperates with the locking ring on the outer wall of the interface module, the needle tube of the medicine extraction needle is tightly sleeved on the outer wall of the interface module on the front end of the injection syringe, and the injection liquid is extracted from the medicine extraction needle into the injection syringe of the syringe by piston movement, and then the first connection part is disassembled; the medicine extraction needle, the interface module and the injection syringe form a medicine extraction channel; Infusion mode: The second connection part of the infusion catheter cooperates with the locking ring on the outer wall of the interface module, and the interface end of the infusion catheter is tightly sleeved on the outer wall of the interface module on the front end of the injection syringe, and the injection liquid is introduced into the infusion catheter and then into the target to be infused through the movement of the piston. The syringe, the interface module and the infusion catheter form an infusion channel; The medicine extraction channel and the perfusion channel are coaxially arranged.

2. The novel bladder instillation device according to claim 1, characterized in that: The interface module is shaped like a columnar structure that matches the inner cavity of the perfusion catheter; the locking ring includes a plurality of raised structures arranged on the outer wall of the interface module, and the raised structure includes a limit plate connected to the outer wall of the interface module, and an end of the limit plate that is not connected to the interface module extends toward the injection syringe to form an arc-shaped fixing plate.

3. The novel bladder instillation device according to claim 2, characterized in that: The first connecting part / the second connecting part is a plurality of hollow grooves arranged in a ring on the inner wall of the interface end of the medicine withdrawal needle / the perfusion catheter, the cross-sectional shape of the hollow groove matches the locking ring, the maximum arc length of a single hollow groove is at least twice the maximum arc length of the limiting plate, and no two adjacent hollow grooves are connected through each other.

4. The novel bladder instillation device according to claim 3, characterized in that: The end of the same side of each hollow groove extends toward the end surface of the interface end to form a guide groove for the locking ring to enter, and the shape and size of the guide groove match the limiting plate.

5. The novel bladder instillation device as claimed in claim 3, characterized in that: The locking ring is made of high-strength polymer material and can be rotated to adjust the tightness of the interface.

6. The novel bladder instillation device according to claim 4, characterized in that: The protruding structure of the locking ring is fixed in the hollow groove at one end away from the guide groove and maintains its fixed state, which is a locked state; the protruding structure is rotated out of the hollow groove toward one end of the guide groove and pulled out of the hollow groove to be an unlocked state.

7. The novel bladder instillation device according to claim 1, characterized in that: The first connecting portion and the medicine withdrawing needle are integrally formed.

8. The novel bladder instillation device according to claim 1, characterized in that: The second connecting portion is integrally formed with the tube body of the irrigation catheter.

9. The novel bladder instillation device according to claim 1, characterized in that: The perfusion catheter is a single-lumen catheter.

10. The novel bladder instillation device according to claim 1, characterized in that: The inner diameter of the input section of the irrigation catheter is smaller than the inner diameter of the output end of the irrigation catheter.

11. The novel bladder instillation device according to claim 9, characterized in that: A one-way valve for preventing backflow is arranged on one side of the inner cavity of the input end of the perfusion catheter close to the input section.

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