Fragrance substance, preparation method thereof and nicotine buccal product

Abstract

The invention provides a fragrant substance, a preparation method thereof and a nicotine buccal product, and the preparation method of the fragrant substance comprises the following steps: S11: uniformly mixing Roibos tea, agave and an extracting agent to obtain a mixture; s12, extracting the mixture, and dissolving the active substances of the Roibos tea and the active substances of the agave in an extracting agent to obtain an extracting solution; and S13, carrying out concentration treatment on the extracting solution to obtain the fragrant substance. The fragrant substance prepared by the method has the advantages of natural fragrance, smooth taste and the like.

Description

Technical Field

[0001] The invention relates to the technical field of nicotine products, in particular to a flavoring substance and a preparation method thereof and a nicotine oral product. Background Art

[0002] Nicotine oral products (including nicotine pouches) are a new type of smokeless tobacco product. Compared with traditional tobacco or electronic cigarettes, they do not burn to produce smoke, so they do not cause secondary harm to the body when used, and they can be smoked in public places (such as on the subway) without affecting other people, making them convenient to use.

[0003] Currently, flavors are generally added to nicotine oral products. Flavors are generally produced through chemical synthesis. The aroma of such chemically synthesized flavors is not natural enough and is prone to have unpleasant smells (similar to the aroma of daily chemical products, which is difficult for some users to accept). It also affects the taste (for example, making the nicotine oral product taste too greasy or pungent), making it difficult for users to keep the product in their mouth until it can be discarded. Summary of the invention

[0004] The purpose of the present invention is to provide a method for preparing a flavor substance. The flavor substance prepared by the method has the advantages of natural fragrance, smooth taste and the like.

[0005] The present invention provides a method for preparing a flavor substance, comprising the following steps:

[0006] S11: mixing rooibos tea, agave and an extractant to obtain a mixture;

[0007] S12: extracting the mixture so that the active substance of the rooibos tea and the active substance of the agave are dissolved in the extractant to obtain an extract;

[0008] S13: The extract is concentrated to obtain aromatic substances.

[0009] In one achievable manner, in the above step S12, the mixture is extracted by at least one of a water bath heating extraction method, an ultrasonic extraction method and a high voltage pulse electric field extraction method.

[0010] In one achievable manner, in the above step S12, the extract is a mixed solution obtained by mixing a plurality of groups of the mixtures after being extracted separately;

[0011] Wherein, at least two groups of the mixtures are extracted by different methods, and / or at least two groups of the mixtures are extracted by different extractants.

[0012] In one achievable manner, in the above step S11, the extractant includes at least one of water and ethanol solution, and the weight ratio of the rooibos tea, the agave and the extractant is (5-10):(3-8):(30-65).

[0013] In one achievable manner, in the above step S13, the extract is concentrated under low temperature and reduced pressure, and the temperature of the low temperature and reduced pressure concentration is controlled at 45°C to 55°C.

[0014] The present invention also provides a flavor substance, which is prepared by the above-mentioned method for preparing the flavor substance.

[0015] The present invention also provides a nicotine oral product, comprising a nicotine mixture, wherein the nicotine mixture comprises nicotine salt and flavor, and the flavor comprises the above-mentioned flavoring substance.

[0016] In one achievable manner, the nicotine mixture further comprises a filler, wherein the filler comprises modified fibers, and the modified fibers are obtained by attaching at least polycaprolactone and chitosan to the surface of plant fibers.

[0017] In a feasible manner, the rooibos tea and the agave form solid residues after extraction, and the plant fiber is prepared from the solid residues.

[0018] In one achievable manner, the nicotine mixture comprises, by weight, 12-30 parts of nicotine salt, 3-10 parts of flavoring agent, 40-60 parts of filler, 0.1-2 parts of dispersant, 1-5 parts of pH adjuster, 10-25 parts of wetting agent and 10-20 parts of flavor.

[0019] The method for preparing flavor substances provided by the present invention comprises extracting rooibos tea and agave, so that the prepared flavor substances contain active substances of rooibos tea and active substances of agave at the same time; wherein the active substances of rooibos tea are rich in various antioxidants, such as flavonoids, phenolic acids and catechins, and the active substances of agave are rich in polyphenols and bioactive components, and these natural components can effectively remove free radicals and reduce the damage of oxidative stress to the body, and at the same time, the antioxidants help to reduce blood lipids and improve blood circulation, thereby reducing the risk of cardiovascular diseases.

[0020] At the same time, the natural ingredients in the flavor substances can give nicotine oral products a unique and natural aroma, and these natural ingredients can improve the taste of nicotine oral products, making them smoother and less irritating. Through the combination of Louis Boss tea and agave for extraction, the flavor substances have the fragrance of plants and the taste of honey, and the taste is fresh and natural. In addition, the agave extract contains sugar, which can bring natural sweetness compared to artificial sweeteners, which can further improve the taste of the product, increase the moistness of the product, and make the nicotine oral products more comfortable when used.

[0021] At the same time, the antioxidants in the flavor substances can protect nicotine and other active ingredients in nicotine oral products, reduce product deterioration caused by factors such as light and temperature changes, and extend the shelf life of the product. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 Schematic diagram of the comparison of nicotine release curves of Example 1, Comparative Example 1 and Comparative Example 2 of the present invention. DETAILED DESCRIPTION

[0023] The specific embodiments of the present invention are described in further detail below. The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention. The terms "first", "second", "third", "fourth", etc. (if any) in the specification and claims of the present invention are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequential order.

[0024] The embodiment of the present invention provides a method for preparing a flavoring substance, wherein the flavoring substance is used in a nicotine oral product (such as a nicotine bag). The method for preparing the flavoring substance comprises the following steps:

[0025] S11: mixing rooibos tea, agave, and an extractant to obtain a mixture;

[0026] S12: extracting the mixture so that the active substance of the rooibos tea and the active substance of the agave are dissolved in the extractant to obtain an extract, that is, the extract includes the extractant and the active substance of the rooibos tea and the active substance of the agave dissolved in the extractant;

[0027] S13: The extract is concentrated to remove at least part of the extractant in the extract (i.e., after the concentration, the extractant in the extract can be completely / almost completely removed, or most of it can be removed, etc.), so as to obtain flavor substances; the flavor substances contain both active substances of Rooibos tea and active substances of agave.

[0028] In the above step S11, the rooibos tea is a common beverage on the market, which is generally made from leguminous shrubs and needle-shaped acid-resistant plants. The agave is generally selected from agave leaves (i.e. leaves of agave).

[0029] The method for preparing flavor substances provided in the embodiment of the present invention extracts rooibos tea and agave, so that the prepared flavor substances contain both active substances of rooibos tea and active substances of agave; wherein the active substances of rooibos tea are rich in various antioxidants, such as flavonoids, phenolic acids and catechins, and the active substances of agave are rich in polyphenols and bioactive ingredients, these natural ingredients can effectively remove free radicals and reduce the damage of oxidative stress to the body, and antioxidants help to lower blood lipids and improve blood circulation, thereby reducing the risk of cardiovascular diseases.

[0030] At the same time, the natural ingredients in the flavor substances can give nicotine oral products a unique and natural aroma, and these natural ingredients can improve the taste of nicotine oral products, making them smoother and less irritating. Through the combination of Louis Boss tea and agave for extraction, the flavor substances have the fragrance of plants and the taste of honey, and the taste is fresh and natural. In addition, the agave extract contains sugar, which can bring natural sweetness compared to artificial sweeteners, which can further improve the taste of the product, increase the moistness of the product, and make the nicotine oral products more comfortable when used.

[0031] At the same time, the antioxidants in the flavor substances can protect nicotine and other active ingredients in nicotine oral products, reduce product deterioration caused by factors such as light and temperature changes, and extend the shelf life of the product.

[0032] As an embodiment, in the above step S11, the rooibos tea is in a powdered structure after being crushed and sifted in sequence, and the agave is in a block structure after being cut, so as to facilitate the uniform mixing of the rooibos tea and agave with the extractant and improve the subsequent extraction efficiency.

[0033] In the specific operation, the rooibos tea can be baked in an oven for a period of time (for example, at a temperature of 50° C.-55° C. for 5-8 hours), then crushed with a grinder, and then sieved (for example, through a 60-80 mesh sieve) to obtain rooibos tea powder. Agave leaves are cut into small pieces to obtain agave blocks for later use.

[0034] As an implementation mode, before the above step S11, the rooibos tea and the agave are first soaked in a soaking liquid for a preset time to improve the subsequent extraction efficiency; the soaking liquid can specifically be water.

[0035] In specific operations, the rooibos tea powder and the cut agave pieces can be added to a proper amount of soaking liquid and soaked for a period of time (eg, 12 hours) to soften the cell walls of the rooibos tea and agave, thereby improving the subsequent extraction efficiency.

[0036] As an implementation manner, the above step S11 may specifically be: adding rooibos tea powder and agave blocks to an appropriate amount of extractant, mixing them evenly, to obtain a mixture.

[0037] As an embodiment, in the above step S11, the extractant includes at least one of water and ethanol solution, and the weight ratio of the rooibos tea, the agave and the extractant is (5-10): (3-8): (30-65). The weight ratio of the rooibos tea, the agave and the extractant can be determined according to the type of the extractant and the extraction method used in step S12.

[0038] As an embodiment, the above-mentioned step S12 specifically includes: extracting the mixture to dissolve the active substances of the rooibos tea and the active substances of the agave in the extractant, and then filtering the mixture to filter out the solid residue formed by the rooibos tea and the agave after extraction (the solid residue is mainly the plant fiber part of the rooibos tea and the agave that is not dissolved in the extractant) to obtain an extract.

[0039] As an embodiment, in the above step S12, when extracting the mixture, the mixture can be extracted by at least one method selected from the group consisting of a water bath heating extraction method, an ultrasonic extraction method, and a high-voltage pulse electric field extraction method.

[0040] The specific steps of the water bath heating extraction method may be: heating the mixture in a water bath at a certain temperature (e.g., 50°C-90°C) for a period of time (e.g., 12 hours), during which the mixture is continuously stirred; after the extraction is completed, the mixture is filtered using filter paper to filter out the solid residue to obtain an extract.

[0041] The specific steps of the ultrasonic extraction method may be: placing the mixture into an ultrasonic cleaner, setting the power and heating temperature of the ultrasonic cleaner (for example, setting the power to 200 W and the heating temperature to 50° C.), and then extracting for a period of time (for example, 23 hours); after the extraction is completed, filtering the mixture with filter paper to filter out the solid residue to obtain an extract.

[0042] The specific steps of the high-voltage pulse electric field extraction method can be: placing the mixture into a high-voltage pulse electric field extraction device, setting the electric field strength and pulse frequency of the high-voltage pulse electric field extraction device (for example, setting the electric field strength to 20-30KV / cm and the pulse frequency to 100-200Hz), and then extracting for a period of time (for example, 12 minutes); after the extraction is completed, using filter paper to filter the mixture to filter out the solid residue to obtain an extract.

[0043] The specific principles and operation steps of the water bath heating extraction method, ultrasonic extraction method and high voltage pulse electric field extraction method can be referred to the prior art, which will not be described in detail here. Of course, in other embodiments, other methods can also be used for extraction.

[0044] As an embodiment, in the above step S12, the extract is a mixed solution obtained by mixing multiple groups (including two groups) of the mixtures after extraction; wherein at least two groups of the mixtures are extracted by different methods, and / or at least two groups of the mixtures use different extractants. In this way, by using a variety of different extraction methods and / or different extractants, the different active ingredients in Rooibos tea and agave can be fully extracted to ensure the diversity and integrity of the extracted ingredients, thereby improving the taste and richness of the aroma of the flavor substances; at the same time, by using different extraction methods, the extraction efficiency can be significantly improved (multiple methods can be performed simultaneously) and the extraction time can be shortened.

[0045] As an embodiment, in the above-mentioned step S12, the extract is a mixed solution obtained by mixing four groups of mixtures after extraction, and the four groups of mixtures are respectively a first group of mixtures, a second group of mixtures, a third group of mixtures and a fourth group of mixtures, and the weight ratio of the first group of mixtures, the second group of mixtures, the third group of mixtures and the fourth group of mixtures can be 1:1:1:1 (or other ratios). Among them, the extractant in the first group of mixtures is water, and the first group of mixtures is extracted by water bath heating extraction to obtain a water extract; the extractant in the second group of mixtures is ethanol solution, and the second group of mixtures is extracted by water bath heating extraction to obtain an ethanol extract; the extractant in the third group of mixtures is ethanol solution, and the third group of mixtures is extracted by ultrasonic extraction to obtain an ultrasonic extract; the extractant in the fourth group of mixtures is ethanol solution, and the fourth group of mixtures is extracted by high-voltage pulse electric field extraction to obtain a high-voltage pulse electric field extract. After the four groups of mixtures are extracted, the water extract, ethanol extract, ultrasonic extract and high-voltage pulse electric field extract are mixed to obtain the extract. Among them, according to the different extraction methods and types of extractants, the weight ratio of rooibos tea, agave and extractant is also different. For example, the ratio of rooibos tea, agave and water in the first group of mixtures can be 5:4:45, the ratio of rooibos tea, agave and ethanol solution in the second group of mixtures can be 5:3:40, the ratio of rooibos tea, agave and ethanol solution in the third group of mixtures can be 5:3:40, and the ratio of rooibos tea, agave and ethanol solution in the fourth group of mixtures can be 8:5:60. Of course, in other embodiments, the extract can also be obtained by extracting using other extraction methods and combinations of extractants.

[0046] As another embodiment, the extract is obtained by extracting the mixture by multiple methods. For example, the mixture is extracted by two or three methods of water bath heating extraction, ultrasonic extraction and high voltage pulse electric field extraction, which can also improve the diversity and integrity of the extracted components.

[0047] As an embodiment, in the above-mentioned step S13, when the extract is concentrated, the extract is concentrated by low temperature and reduced pressure, and the temperature of the low temperature and reduced pressure concentration is controlled at 45°C to 55°C. The low temperature and reduced pressure concentration can reduce the damage to the active substances in the extract and ensure the stability of the active substances in the extract as much as possible. Among them, low temperature and reduced pressure concentration is to reduce the boiling temperature of the extract by vacuuming at a lower temperature, so that the extract evaporates and dries; the specific steps of the low temperature and reduced pressure concentration can refer to the prior art and will not be repeated here.

[0048] As an embodiment, in the above step S13, after the extract is concentrated, the extract is filtered using a microfiltration membrane to remove residues in the extract. Specifically, during the concentration process, a thin film may appear on the surface of the extract, or there may be tiny residues in the extract that are not filtered out; by filtering with a microfiltration membrane, these thin films and tiny residues can be filtered out. The pore size of the micropores on the microfiltration membrane can be selected according to actual needs, for example, 0.45 microns.

[0049] The embodiment of the present invention further provides a flavoring substance, which is prepared by the above-mentioned method for preparing a flavoring substance, that is, the flavoring substance is obtained by extracting active substances from rooibos tea and active substances from agave.

[0050] The present invention also provides a method for preparing a modified fiber, wherein the modified fiber is used for a nicotine oral product. The method for preparing the modified fiber comprises the following steps:

[0051] S21: providing a modification liquid, wherein the modification liquid contains polycaprolactone (PCL) and chitosan;

[0052] S22: immersing the plant fiber in the modification liquid, so that the polycaprolactone and chitosan in the modification liquid adhere to the surface of the plant fiber to obtain a coated fiber;

[0053] S23: Drying the coated fiber to obtain modified fiber.

[0054] The preparation method of the modified fiber provided in the embodiment of the present invention utilizes polycaprolactone and chitin to modify the plant fiber. On the one hand, polycaprolactone and chitin themselves have good water absorption, so polycaprolactone and chitin attached to the surface of the plant fiber can improve the water absorption of the plant fiber; on the other hand, polycaprolactone and chitin can be cross-linked with the plant fiber to form a three-dimensional network structure on the surface of the plant fiber, and the three-dimensional network structure has good water absorption, thereby further improving the water absorption of the plant fiber. Therefore, when the modified fiber is used as a filler for nicotine oral products, the product can have higher water absorption, so that the product can absorb a large amount of saliva in a short time when used, thereby accelerating the dilution and release of nicotine in the product, improving the release efficiency and maximum release of nicotine, and contributing to the uniform release of nicotine, thereby improving the user experience.

[0055] At the same time, the above three-dimensional network structure can improve the structural strength of the plant fiber, so that the modified fiber has good toughness and shape retention ability, reduce the risk of modified fiber breakage during production and transportation, and improve the quality of the product (ordinary plant fibers are weak in strength and are prone to brittle breakage and formation of fragments during production and transportation, thereby affecting the user experience). Moreover, the above three-dimensional network structure can also improve the thermal stability of the plant fiber, thereby increasing the scope of application of the modified fiber. At the same time, this modified fiber is relatively soft compared to certain types of fillers (such as microcrystalline cellulose, which is a crystalline solid with a hard texture). Using it as a filler can improve the softness and comfort of the filler and reduce the user's discomfort when holding the product in the mouth.

[0056] At the same time, the modified fiber uses plant fiber as a matrix, polycaprolactone is a biodegradable polymer, and chitosan is a natural polysaccharide. The use of these materials can make the modified fiber healthier and more natural, and reduce harm to the human body.

[0057] As an embodiment, in the above step S21, in the modified liquid, the weight ratio of the polycaprolactone to the chitosan is (4.5-5.5):(2-3). As an embodiment, the weight ratio of the polycaprolactone to the chitosan is 5:2.5.

[0058] As an embodiment, in the above step S21, the modified solution further contains succinic acid. By adding succinic acid, succinic acid can promote the cross-linking of polycaprolactone and chitin with plant fibers, thereby promoting the formation and stability of a three-dimensional network structure and improving the performance of the modified fiber.

[0059] As an embodiment, in the modified liquid, the weight ratio of the polycaprolactone, the chitosan and the succinic acid is (4.5-5.5):(2-3):(0.5-1.5). As an embodiment, the weight ratio of the polycaprolactone, the chitosan and the succinic acid is 5:2.5:1.

[0060] As an embodiment, in the above-mentioned S21 step, the modified liquid is at least mixed by a first solution and a second solution. The first solution is formed by dissolving polycaprolactone in ethanol, and the ratio of polycaprolactone to ethanol can be set according to actual needs, and it is only necessary to ensure that polycaprolactone can be completely dissolved (for example, 5g of polycaprolactone is dissolved in 500mL of ethanol); the second solution is formed by dissolving chitosan in acetic acid solution, and the ratio of chitosan to acetic acid solution can be set according to actual needs, and it is only necessary to ensure that chitosan can be completely dissolved (for example, 2.5g of chitosan is dissolved in 500mL of 1% acetic acid solution). Among them, polycaprolactone is a biodegradable polymer that can be dissolved in ethanol to form a uniform solution; chitosan is a natural polysaccharide that can be dissolved in acetic acid solution to form a uniform solution. Using ethanol and acetic acid solution as dissolving liquid can reduce the harm to the human body.

[0061] Specifically, the specific preparation steps of the modified liquid can be:

[0062] (1) Add polycaprolactone to ethanol, ensure that the polycaprolactone is completely immersed in the ethanol, and then heat and stir at a certain temperature for a period of time (for example, place in a constant temperature water bath, heat and stir at 60° C. for 12 hours) until the polycaprolactone is completely dissolved to form a transparent polycaprolactone solution.

[0063] (2) Add chitosan to the acetic acid solution, and then stir for a period of time (for example, using a magnetic stirrer to stir for 23 hours) until the chitosan is completely dissolved to form a transparent chitosan solution.

[0064] (3) The polycaprolactone solution and the chitosan solution are mixed and stirred for a period of time (for example, using a magnetic stirrer to stir for 10 minutes) to ensure that the two solutions are evenly mixed to obtain a mixed solution.

[0065] (4) Add succinic acid to the mixed solution and continue stirring for a period of time (for example, using a magnetic stirrer to stir for 10 minutes) to ensure that the succinic acid is completely dissolved and evenly dispersed, thereby obtaining a modified solution.

[0066] As an embodiment, in the above step S22, the length of the plant fiber is 11 mm to 13 mm. The length of the plant fiber should not be too long or too short, which is not conducive to the combination of polycaprolactone and chitin with the plant fiber, and is not convenient for subsequent bagging. As an embodiment, the length of the plant fiber is 12 mm.

[0067] As an embodiment, in the above step S22, the plant fiber is prepared from the solid residue formed after rooibos tea and agave are extracted (i.e., rooibos tea and agave form solid residue after extraction, and the solid residue is mainly the plant fiber part of rooibos tea and agave that is not dissolved in the extractant, and the plant fiber is prepared from the solid residue). In this way, not only can the waste of raw materials be reduced, the utilization rate of raw materials be improved, and costs be saved, but also the preparation efficiency of plant fibers can be improved (if the solid residue of rooibos tea and agave is not used when preparing plant fibers, but other plant bodies are additionally used as raw materials, then the plant bodies also need to go through steps such as extraction and separation, thereby increasing costs and reducing production efficiency).

[0068] Specifically, the steps of preparing the plant fiber may be:

[0069] (a) washing the solid residues of the rooibos tea and agave to remove impurities on the surface of the solid residues;

[0070] (b) soaking the solid residue in an alkali solution for a period of time (e.g., soaking in a sodium hydroxide solution for 12 hours) to remove lignin and hemicellulose in the solid residue;

[0071] (c) soaking the solid residue in a bleaching agent for a period of time (e.g., soaking in a sodium hypochlorite solution for 12 hours) to remove the pigment in the solid residue;

[0072] (d) washing the solid residue to remove residual alkali solution and bleaching agent;

[0073] (e) crushing and drying the solid residue to obtain the plant fiber.

[0074] Specifically, the above step (a) may be: putting the solid residues of Rooibos tea and agave into clean water, stirring gently with a stirrer to remove impurities on the surface of the solid residues; and then separating the washed solid residues from the water with a filter.

[0075] The above step (b) may specifically be: placing the washed solid residue in a 12% sodium hydroxide solution, stirring gently with a stirrer to ensure that the sodium hydroxide solution is evenly distributed, and soaking for 12 hours; then filtering the soaked solid residue to remove the sodium hydroxide solution.

[0076] The above step (c) may specifically be: placing the solid residue in an 8% sodium hypochlorite solution, gently stirring with a stirrer to ensure that the sodium hypochlorite solution is evenly distributed, and soaking for 12 hours; then filtering the soaked solid residue to remove the sodium hypochlorite solution. Then, treating the solid residue with dilute hydrochloric acid to neutralize the sodium hypochlorite to ensure that the solid residue is neutral.

[0077] The above step (d) may specifically be: placing the solid residue in clean water and rinsing it multiple times to ensure that the residual sodium hydroxide and sodium hypochlorite are completely removed; after rinsing, using a filter to separate the solid residue and water.

[0078] The above step (e) may specifically be: using a pulverizer to crush the solid residue into small pieces of a preset length (e.g., 12 mm); then using an oven to dry the solid residue to reduce the water content of the solid residue to below a preset value (e.g., 10%) for later use.

[0079] As another embodiment, in the preparation of plant fiber, if the solid residues of Rooibos tea and agave are not used as raw materials, for example, plant bodies are used as raw materials (the plant bodies include but are not limited to Rooibos tea, agave, etc.), the plant bodies need to first be processed through extraction and separation steps (the specific operation steps can refer to the extraction steps of Rooibos tea and agave mentioned above, which are not repeated here) to obtain solid residues, and then the solid residues are processed through the above steps (a) to (e).

[0080] As an embodiment, in the above step S22, after immersing the plant fiber in the modifying liquid, the plant fiber and the modifying liquid are also subjected to ultrasonic treatment to ensure that the modifying liquid is fully immersed in the surface of the plant fiber, thereby ensuring that polycaprolactone and chitosan are evenly distributed on the surface of the plant fiber.

[0081] Specifically, the S22 step may be: placing the plant fiber in the modification liquid, ensuring that the plant fiber is completely immersed in the modification liquid, using an ultrasonic cleaner to perform ultrasonic treatment on the plant fiber and the modification liquid for 10-15 minutes, ensuring that the modification liquid is fully immersed in the surface of the plant fiber to obtain coated fibers.

[0082] As an embodiment, in the above step S23, the coated fiber is dried, specifically comprising:

[0083] S231: placing the coated fiber in a microwave drying device for a first drying treatment;

[0084] S232: washing the coated fiber to remove the residual modification liquid on the surface of the coated fiber;

[0085] S233: performing a second drying process on the coated fiber.

[0086] Among them, step S231 is to perform microwave drying on the coated fiber in order to dry and solidify the polycaprolactone and chitosan on the surface of the plant fiber; and the use of microwave heating can ensure the uniformity of heating, avoid the problem of the coated fiber being dry outside and wet inside, and improve the drying rate. Step S232 is to wash the coated fiber in order to remove the excess modification liquid that is not attached to the surface of the plant fiber and avoid the modification liquid causing odor.

[0087] Step S231 may specifically be: use filter paper to absorb excess modification liquid on the surface of the coated fiber, then evenly spread the coated fiber on the tray of the microwave drying equipment, place the tray into the microwave drying equipment, set the power to medium-high power (e.g. 800W), and dry for 10-15 minutes to ensure that the ethanol on the surface of the coated fiber is completely removed.

[0088] Step S232 may specifically be: placing the dried coated fiber into a beaker, adding a certain amount of distilled water, stirring gently with a glass rod to ensure that the coated fiber is completely soaked, treating with an ultrasonic cleaner for a period of time (e.g., 5 minutes) to remove the residual modification liquid on the surface of the coated fiber; repeating the above steps three times to ensure that the surface of the coated fiber is clean.

[0089] Step S233 may specifically be: use filter paper to absorb moisture on the surface of the coated fiber, then evenly spread the coated fiber on a tray of the oven, put the tray into the oven and heat it for a period of time (for example, drying at 60°C for 12 hours) to ensure that the moisture is completely removed (of course, other drying methods can also be used during the second drying process).

[0090] The embodiment of the present invention further provides a modified fiber, which is made by the modified fiber preparation method as described above, that is, the modified fiber is obtained by at least polycaprolactone and chitosan attached to the surface of plant fiber.

[0091] In order to verify the performance of the modified fiber, the following comparative tests were designed:

[0092] 1. Preparing solid residue: mixing rooibos tea, agave and an extractant to obtain a mixture, extracting and separating the mixture to obtain a solid residue (the steps for preparing the solid residue may refer to the steps for preparing the aroma substances described above).

[0093] 2. Preparation of modified fiber:

[0094] 1. Preparation of plant fiber:

[0095] Put the solid residues of Rooibos tea and agave into clean water and stir gently with a blender to remove impurities on the surface of the solid residues; then use a filter to separate the cleaned solid residues from the water.

[0096] The cleaned solid residue is placed in a 12% sodium hydroxide solution, gently stirred with a stirrer to ensure that the sodium hydroxide solution is evenly distributed, and soaked for 12 hours; then the soaked solid residue is filtered to remove the sodium hydroxide solution.

[0097] Place the solid residue in an 8% sodium hypochlorite solution, stir gently with a stirrer to ensure that the sodium hypochlorite solution is evenly distributed, and soak for 12 hours; then filter the soaked solid residue to remove the sodium hypochlorite solution. Then treat the solid residue with dilute hydrochloric acid to neutralize the sodium hypochlorite and ensure that the solid residue is neutral.

[0098] Place the solid residue in clean water and rinse it several times to ensure that the residual sodium hydroxide and sodium hypochlorite are completely removed; after rinsing, use a filter to separate the solid residue and water.

[0099] The solid residue is crushed by a pulverizer into small pieces of 12 mm. Then, the solid residue is dried in an oven to reduce the water content of the solid residue to less than 10%, thereby obtaining plant fibers.

[0100] 2. Preparation of modified liquid:

[0101] Weigh 5 g of polycaprolactone using an electronic balance, add 5 g of polycaprolactone to 500 mL of ethanol, ensure that the polycaprolactone is completely immersed in the ethanol, and then place it in a constant temperature water bath, set the heating temperature to 60°C, and stir with a magnetic stirrer for 12 hours until the polycaprolactone is completely dissolved to form a transparent polycaprolactone solution.

[0102] 2.5 g of chitosan was weighed using an electronic balance, and added into 500 mL of 1% acetic acid solution. The mixture was stirred for 23 hours using a magnetic stirrer until the chitosan was completely dissolved to form a transparent chitosan solution.

[0103] The polycaprolactone solution and the chitosan solution were mixed and stirred for 10 minutes using a magnetic stirrer to ensure that the two solutions were evenly mixed to obtain a mixed solution.

[0104] 1 g of succinic acid was weighed using an electronic balance, and added to the mixed solution. The solution was stirred for 10 minutes using a magnetic stirrer to ensure that the succinic acid was completely dissolved and evenly dispersed to obtain a modified solution.

[0105] 3. Preparation of modified fiber:

[0106] Place 50 g of plant fiber in 500 mL of modification liquid, ensure that the plant fiber is completely immersed in the modification liquid, use an ultrasonic cleaner to perform ultrasonic treatment on the plant fiber and the modification liquid for 12 minutes, ensure that the modification liquid is fully immersed in the surface of the plant fiber, and obtain coated fiber.

[0107] Use filter paper to absorb excess modification liquid on the surface of the coated fiber, then evenly spread the coated fiber on the tray of the microwave drying equipment, put the tray into the microwave drying equipment, set the power to medium-high power (800W), and dry for 10-15 minutes to ensure that the ethanol on the surface of the coated fiber is completely removed.

[0108] Place the dried coated fiber in a beaker, add 500 mL of distilled water, gently stir with a glass rod to ensure that the coated fiber is completely soaked, and treat with an ultrasonic cleaner for 5 minutes to remove the residual modification liquid on the surface of the coated fiber; repeat the above steps three times to ensure that the surface of the coated fiber is clean.

[0109] The moisture on the surface of the coated fiber was absorbed with filter paper, and then the coated fiber was evenly spread on a tray of an oven, and the tray was placed in the oven and dried at 60° C. for 12 hours to ensure that the moisture was completely removed to obtain modified fibers.

[0110] 3. Test:

[0111] 1. Mechanical properties test

[0112] Testing equipment: Universal material testing machine

[0113] Test parameters: tensile strength (MPa), elongation at break (%)

[0114] Test steps:

[0115] (1) A universal material testing machine was used to perform tensile tests on the modified fiber, unmodified fiber (the unmodified fiber specifically refers to the plant fiber prepared as described above; that is, the unmodified fiber has not been impregnated with the modification liquid compared to the modified fiber) and microcrystalline cellulose, and the tensile strength and elongation at break measured each time were recorded.

[0116] (2) Each material was tested multiple times (5 times in this example) and the average value was taken.

[0117] The test results are shown in the following table:

[0118] sample Number of trials Tensile strength(MPa) Elongation at break (%) Modified Fiber 1 178±7 19±3 Modified Fiber 2 182±6 21±2 Modified Fiber 3 180±5 20±2 Modified Fiber 4 181±6 20±3 Modified Fiber 5 180±5 20±2 Unmodified Fiber 1 118±5 9±2 Unmodified Fiber 2 122±6 11±2 Unmodified Fiber 3 119±4 10±1 Unmodified Fiber 4 121±5 10±2 Unmodified Fiber 5 120±4 10±1 Microcrystalline Cellulose 1 148±5 14±2 Microcrystalline Cellulose 2 152±4 15±2 Microcrystalline Cellulose 3 150±5 15±1 Microcrystalline Cellulose 4 151±4 15±2 Microcrystalline Cellulose 5 150±5 15±1

[0119] From the table above, we can see that the average tensile strength of the modified fiber is 180.2MPa, which is significantly higher than the average tensile strength of the unmodified fiber (120.4MPa) and the average tensile strength of microcrystalline cellulose (150.2MPa); the average elongation at break of the modified fiber is 20.0%, which is significantly higher than the average elongation at break of the unmodified fiber (10.0%) and the average elongation at break of microcrystalline cellulose (14.8%). It can be seen that the modified fiber has better structural strength than the unmodified fiber and microcrystalline cellulose.

[0120] 2. Hydrophilicity test

[0121] Testing equipment: Contact angle tester

[0122] Test parameters: Contact angle (°)

[0123] Test steps:

[0124] (1) Place the modified fiber, unmodified fiber and microcrystalline cellulose on the sample stage of the contact angle tester respectively.

[0125] (2) Add a certain amount of water droplets to various materials and record the contact angle between the water droplets and the fiber surface.

[0126] (3) Repeat the test multiple times (5 times in this example) and take the average value.

[0127] The test results are shown in the following table:

[0128] Samples / Times Modified fiber(°) Unmodified fiber(°) Microcrystalline cellulose(°) 1 44±3 83±3 68±3 2 46±2 87±3 72±3 3 45±3 85±2 70±2 4 45±2 84±3 71±3 5 46±3 86±2 70±2

[0129] As can be seen from the table above, the average contact angle of the modified fiber is 45.2°, which is significantly lower than the average contact angle of the unmodified fiber (85.0°) and the average contact angle of microcrystalline cellulose (70.0°). This shows that the modified fiber has better hydrophilicity than the unmodified fiber and microcrystalline cellulose.

[0130] 3. Thermal stability test

[0131] Testing equipment: Thermogravimetric analyzer (TGA)

[0132] Test parameters: Thermal decomposition temperature (℃)

[0133] Test steps:

[0134] (1) Place modified fiber, unmodified fiber and microcrystalline cellulose in the sample pan of a thermogravimetric analyzer.

[0135] (2) Under a nitrogen atmosphere, the temperature of the thermogravimetric analyzer was raised from room temperature to 500°C at a heating rate of 10°C / min, and the thermal decomposition temperature of each material was recorded.

[0136] (3) Repeat the test multiple times (5 times in this example) and take the average value.

[0137] The test results are shown in the following table:

[0138] Samples / Times Modified fiber(℃) Unmodified fiber(℃) Microcrystalline cellulose(℃) 1 318±4 278±5 298±5 2 322±4 282±5 302±5 3 320±3 280±4 300±4 4 321±4 281±5 301±5 5 320±3 280±4 300±4

[0139] As can be seen from the table above, the average thermal decomposition temperature of the modified fiber is 320.2°C, which is significantly higher than the average thermal decomposition temperature of the unmodified fiber of 280.2°C and the average thermal decomposition temperature of microcrystalline cellulose of 300.2°C. This shows that the modified fiber has better thermal stability than the unmodified fiber and microcrystalline cellulose.

[0140] The embodiment of the present invention further provides a nicotine oral product, including a packaging bag and a nicotine mixture arranged in the packaging bag. The nicotine oral product can specifically be a nicotine bag.

[0141] As an embodiment, the nicotine mixture includes nicotine salt and a filler, and the filler includes the modified fiber as described above, that is, the modified fiber is obtained by attaching at least polycaprolactone and chitosan to the surface of plant fiber. As another embodiment, the filler includes one or more of the modified fiber, microcrystalline cellulose, and starch.

[0142] As an embodiment, the nicotine mixture further includes flavors, and the flavors include the above-mentioned flavoring substances, that is, the flavoring substances are obtained by extracting active substances from rooibos tea and active substances from agave. As another embodiment, the flavors include one or more of the above-mentioned flavoring substances, apple flavors, peach flavors, berry flavors, banana flavors, lychee flavors, and watermelon flavors.

[0143] As an embodiment, the rooibos tea and the agave form solid residue after extraction; in the above step S22, the plant fiber is prepared from the solid residue.

[0144] As an embodiment, the nicotine mixture further comprises a flavoring agent, a dispersant, a pH adjusting agent and a wetting agent. In terms of weight, the nicotine mixture comprises 12-30 parts of nicotine salt, 3-10 parts of a flavoring agent, 40-60 parts of a filler, 0.1-2 parts of a dispersant, 1-5 parts of a pH adjusting agent, 10-25 parts of a wetting agent and 10-20 parts of an essence; wherein the flavoring agent comprises a sweetener and a cooling agent, and the weight ratio of the sweetener to the cooling agent is (0.5-1):(8-10).

[0145] As an embodiment, nicotine salts include one or more of nicotine tartaric acid salts, nicotine levulinate salts, nicotine benzoate salts, nicotine lactate salts, and nicotine citric acid salts. Sweeteners include one or more of nutame, advantame, sucralose, stevioside, and xylitol. Cooling agents include one or more of menthol, WS-23 cooling agents, WS-3 cooling agents, WS-5 cooling agents, and WS-27 cooling agents. Dispersants include one or more of guar gum, carrageenan, gum arabic, and sodium alginate. pH regulators include one or more of sodium carbonate, sodium bicarbonate, and sodium chloride. Wetting agents include one or more of deionized water, propylene glycol (PG), and glycerol (VG).

[0146] Among them, flavoring agents can increase the flavor of the product and provide more sensory experience. On the one hand, fillers can act as carriers, that is, other ingredients in the nicotine mixture will be dispersed on the surface of the filler, so that the components are evenly dispersed; on the other hand, they can absorb water. When the user holds the nicotine oral product in the mouth, the filler can absorb the saliva in the mouth, so that the saliva will infiltrate the nicotine mixture, and then release nicotine into the mouth. Dispersants can make the components in the nicotine mixture mix more evenly and maintain the shape of the product. pH regulators can adjust the pH of the nicotine mixture to adapt it to the pH of the human oral environment, and pH regulators can promote the release of nicotine. Wetting agents can prevent the nicotine mixture from drying and cracking, avoid the components in the nicotine mixture from being too dispersed and causing leakage, and can promote the release of nicotine. Flavors can improve the flavor of the product, provide more sensory experience, and mask the chemical smell of the product (such as masking the taste of nicotine).

[0147] As an embodiment, the preparation steps of the nicotine oral product may be:

[0148] Mix and stir 10-20 parts of flavor, 12-30 parts of nicotine salt and 10-25 parts of wetting agent to obtain a mixed liquid;

[0149] 3-10 parts of flavoring agent, 40-60 parts of filler, 0.1-2 parts of dispersant and 1-5 parts of pH adjuster are mixed uniformly to obtain a mixed powder;

[0150] The mixed liquid and the mixed powder are uniformly mixed to obtain a nicotine mixture, and then the nicotine mixture is sieved (for example, through a 40-mesh sieve to make the powder more delicate and prevent agglomeration), and then the nicotine mixture is bagged (for example, 0.3 g of the nicotine mixture is loaded into each packaging bag), and finally sterilized by ultraviolet light to obtain a nicotine oral product (nicotine bag).

[0151] As an implementation method, the packaging bag is generally a medical-grade or food-grade non-woven fabric. When a user uses a nicotine oral product, after putting the nicotine oral product into the mouth, the saliva in the mouth will be sucked into the packaging bag by the filler and other ingredients, and then the saliva will infiltrate the nicotine mixture, so that the nicotine in the nicotine mixture is released into the mouth along with the saliva.

[0152] Example 1

[0153] 1. Preparation of flavor substances:

[0154] 1. Place the Rooibos tea in an oven and bake at 50°C for 6 hours, then crush the Rooibos tea with a grinder, and then sieve the Rooibos tea (through a 60-mesh sieve) to obtain Rooibos tea powder. Cut the agave leaves into small pieces to obtain agave blocks, and set aside.

[0155] 2. Soak the Rooibos tea powder and chopped agave pieces in water for 12 hours to soften the cell walls and improve subsequent extraction efficiency.

[0156] 3. Prepare an aqueous extract: add 30 g of rooibos tea powder and 24 g of agave blocks to 270 g of water, mix well, and obtain a mixture; then heat the mixture in a water bath at 85° C. (specifically, it can be controlled in the range of 80° C.-90° C.) for 12 hours, during which the mixture is continuously stirred; after the extraction is completed, filter the mixture with filter paper to filter out solid residues to obtain an aqueous extract.

[0157] Preparation of ethanol extract: 15 g of rooibos tea powder and 9 g of agave blocks are added to 120 g of 70% ethanol solution, mixed evenly, and a mixture is obtained; the mixture is then heated in a water bath at 55° C. (specifically, it can be controlled in the range of 50° C.-60° C.) for 12 hours, during which the mixture is continuously stirred; after the extraction is completed, the mixture is filtered using filter paper to filter out solid residues to obtain an ethanol extract.

[0158] Preparation of ultrasonic extract: adding 15 g of rooibos tea powder and 9 g of agave blocks to 120 g of 70% ethanol solution, mixing evenly to obtain a mixture; placing the mixture in an ultrasonic cleaner, setting the power to 200 W, the heating temperature to 50° C., and extracting for 23 hours; after the extraction is completed, filtering the mixture with filter paper to filter out solid residues to obtain an ultrasonic extract.

[0159] Preparation of high-voltage pulsed electric field extract: adding 24 g of Rooibos tea powder and 15 g of agave blocks to 180 g of 70% ethanol solution, mixing evenly to obtain a mixture; placing the mixture into a high-voltage pulsed electric field extraction device, setting the electric field strength of the high-voltage pulsed electric field extraction device to 25 KV / cm, the pulse frequency to 120 Hz, and extracting for 12 minutes; after the extraction is completed, filtering the mixture with filter paper to filter out solid residues to obtain a high-voltage pulsed electric field extract.

[0160] 4. Mix the water extract, ethanol extract, ultrasonic extract and high-voltage pulse electric field extract in a weight ratio of 1:1:1:1 to obtain an extract.

[0161] 5. The extract is subjected to low-temperature, reduced-pressure and concentrated treatment at a temperature of 45°C until the extractant (water and ethanol) in the extract is completely evaporated; then the extract is filtered using a microfiltration membrane (with a pore size of 0.45 microns) to obtain 60 g of concentrated solution, which is the aroma substance.

[0162] 2. Preparation of modified fiber:

[0163] 1. Preparation of plant fiber:

[0164] The solid residues of Rooibos tea and agave separated in the above step are placed in clean water, and gently stirred with a stirrer to remove impurities on the surface of the solid residues; and then a filter is used to separate the washed solid residues from the water.

[0165] The cleaned solid residue is placed in a 12% sodium hydroxide solution, gently stirred with a stirrer to ensure that the sodium hydroxide solution is evenly distributed, and soaked for 12 hours; then the soaked solid residue is filtered to remove the sodium hydroxide solution.

[0166] Place the solid residue in an 8% sodium hypochlorite solution, stir gently with a stirrer to ensure that the sodium hypochlorite solution is evenly distributed, and soak for 12 hours; then filter the soaked solid residue to remove the sodium hypochlorite solution. Then treat the solid residue with dilute hydrochloric acid to neutralize the sodium hypochlorite and ensure that the solid residue is neutral.

[0167] Place the solid residue in clean water and rinse it several times to ensure that the residual sodium hydroxide and sodium hypochlorite are completely removed; after rinsing, use a filter to separate the solid residue and water.

[0168] The solid residue is crushed by a pulverizer into small pieces of 12 mm. Then, the solid residue is dried in an oven to reduce the water content of the solid residue to less than 10%, thereby obtaining plant fibers.

[0169] 2. Preparation of modified liquid:

[0170] Weigh 5 g of polycaprolactone using an electronic balance, add 5 g of polycaprolactone to 500 mL of ethanol, ensure that the polycaprolactone is completely immersed in the ethanol, and then place it in a constant temperature water bath, set the heating temperature to 60°C, and stir with a magnetic stirrer for 12 hours until the polycaprolactone is completely dissolved to form a transparent polycaprolactone solution.

[0171] 2.5 g of chitosan was weighed using an electronic balance, and added into 500 mL of 1% acetic acid solution. The mixture was stirred for 23 hours using a magnetic stirrer until the chitosan was completely dissolved to form a transparent chitosan solution.

[0172] The polycaprolactone solution and the chitosan solution were mixed and stirred for 10 minutes using a magnetic stirrer to ensure that the two solutions were evenly mixed to obtain a mixed solution.

[0173] 1 g of succinic acid was weighed using an electronic balance, and added to the mixed solution. The solution was stirred for 10 minutes using a magnetic stirrer to ensure that the succinic acid was completely dissolved and evenly dispersed to obtain a modified solution.

[0174] 3. Preparation of modified fiber:

[0175] Place 50 g of plant fiber in 500 mL of modification liquid, ensure that the plant fiber is completely immersed in the modification liquid, use an ultrasonic cleaner to perform ultrasonic treatment on the plant fiber and the modification liquid for 12 minutes, ensure that the modification liquid is fully immersed in the surface of the plant fiber, and obtain coated fiber.

[0176] Use filter paper to absorb excess modification liquid on the surface of the coated fiber, then evenly spread the coated fiber on the tray of the microwave drying equipment, put the tray into the microwave drying equipment, set the power to medium-high power (800W), and dry for 10-15 minutes to ensure that the ethanol on the surface of the coated fiber is completely removed.

[0177] Place the dried coated fiber in a beaker, add 500 mL of distilled water, gently stir with a glass rod to ensure that the coated fiber is completely soaked, and treat with an ultrasonic cleaner for 5 minutes to remove the residual modification liquid on the surface of the coated fiber; repeat the above steps three times to ensure that the surface of the coated fiber is clean.

[0178] The moisture on the surface of the coated fiber was absorbed with filter paper, and then the coated fiber was evenly spread on a tray of an oven, and the tray was placed in the oven and dried at 60° C. for 12 hours to ensure that the moisture was completely removed to obtain modified fibers.

[0179] 3. Preparation of nicotine bags:

[0180] 18 parts of flavoring material, 12 parts of nicotine salt and 15 parts of wetting agent (the wetting agent includes 3.75 parts of propylene glycol and 11.25 parts of deionized water, that is, the ratio of propylene glycol to deionized water is 1:3) are mixed and stirred to obtain a mixed liquid;

[0181] 9.7 parts of flavoring agents (including 0.7 parts of sucralose, 6.75 parts of WS-23 cooling agents, and 2.25 parts of WS-3 cooling agents), 44 parts of modified fiber, 1 part of sodium alginate, and 3 parts of sodium bicarbonate are mixed uniformly to obtain a mixed powder;

[0182] The mixed liquid and the mixed powder are uniformly mixed to obtain a nicotine mixture, and then the nicotine mixture is passed through a 40-mesh sieve, and then the nicotine mixture is put into a non-woven bag (each non-woven bag is filled with 0.3 g of the nicotine mixture), and finally sterilized by ultraviolet light to obtain a nicotine bag.

[0183] Comparative Example 1

[0184] The difference between Comparative Example 1 and Example 1 is that: Comparative Example 1 uses unmodified fiber as a filler (unmodified fiber specifically refers to the plant fiber prepared as described above; that is, the unmodified fiber is not impregnated with a modification liquid compared to the modified fiber). The other components and steps of Comparative Example 1 are the same as those of Example 1.

[0185] Specifically, the steps for preparing the nicotine bag in Comparative Example 1 include:

[0186] 18 parts of flavoring material, 12 parts of nicotine salt and 15 parts of wetting agent (the wetting agent includes 3.75 parts of propylene glycol and 11.25 parts of deionized water, that is, the ratio of propylene glycol to deionized water is 1:3) are mixed and stirred to obtain a mixed liquid;

[0187] 9.7 parts of flavoring agents (including 0.7 parts of sucralose, 6.75 parts of WS-23 cooling agents, and 2.25 parts of WS-3 cooling agents), 44 parts of unmodified fiber, 1 part of sodium alginate, and 3 parts of sodium bicarbonate were mixed to obtain a mixed powder;

[0188] The mixed liquid and the mixed powder are uniformly mixed to obtain a nicotine mixture, and then the nicotine mixture is passed through a 40-mesh sieve, and then the nicotine mixture is put into a non-woven bag (each non-woven bag is filled with 0.3 g of the nicotine mixture), and finally sterilized by ultraviolet light to obtain a nicotine bag.

[0189] Comparative Example 2

[0190] The difference between Comparative Example 2 and Example 1 is that microcrystalline cellulose is used as a filler in Comparative Example 2. The other ingredients and steps of Comparative Example 2 are the same as those of Example 1.

[0191] Specifically, the steps for preparing the nicotine bag in Comparative Example 2 include:

[0192] 18 parts of flavoring material, 12 parts of nicotine salt and 15 parts of wetting agent (the wetting agent includes 3.75 parts of propylene glycol and 11.25 parts of deionized water, that is, the ratio of propylene glycol to deionized water is 1:3) are mixed and stirred to obtain a mixed liquid;

[0193] 9.7 parts of flavoring agents (including 0.7 parts of sucralose, 6.75 parts of WS-23 cooling agents, and 2.25 parts of WS-3 cooling agents), 44 parts of microcrystalline cellulose, 1 part of sodium alginate, and 3 parts of sodium bicarbonate are mixed uniformly to obtain a mixed powder;

[0194] The mixed liquid and the mixed powder are uniformly mixed to obtain a nicotine mixture, and then the nicotine mixture is passed through a 40-mesh sieve, and then the nicotine mixture is put into a non-woven bag (each non-woven bag is filled with 0.3 g of the nicotine mixture), and finally sterilized by ultraviolet light to obtain a nicotine bag.

[0195] Comparative Example 3

[0196] The difference between Comparative Example 3 and Example 1 is that the flavoring material is replaced with agave flavor and rooibos tea flavor in Comparative Example 3. The other ingredients and steps of Comparative Example 3 are the same as those of Example 1.

[0197] Specifically, the steps for preparing the nicotine bag in Comparative Example 3 include:

[0198] 7 parts of agave flavor, 11 parts of rooibos tea flavor, 12 parts of nicotine salt and 15 parts of wetting agent (the wetting agent includes 3.75 parts of propylene glycol and 11.25 parts of deionized water, that is, the ratio of propylene glycol to deionized water is 1:3) are mixed and stirred to obtain a mixed liquid;

[0199] 9.7 parts of flavoring agents (including 0.7 parts of sucralose, 6.75 parts of WS-23 cooling agents, and 2.25 parts of WS-3 cooling agents), 44 parts of modified fiber, 1 part of sodium alginate, and 3 parts of sodium bicarbonate are mixed uniformly to obtain a mixed powder;

[0200] The mixed liquid and the mixed powder are uniformly mixed to obtain a nicotine mixture, and then the nicotine mixture is passed through a 40-mesh sieve, and then the nicotine mixture is put into a non-woven bag (each non-woven bag is filled with 0.3 g of the nicotine mixture), and finally sterilized by ultraviolet light to obtain a nicotine bag.

[0201] The following comparative tests were performed on Example 1 and Comparative Examples 1-3:

[0202] 1. Hydrophilicity test: water absorption comparison (0-30 minutes)

[0203] Water absorption rate test: The nicotine bags prepared in Example 1, Comparative Example 1 and Comparative Example 2 were immersed in simulated saliva, and the water absorption (mg) was measured every 5 minutes.

[0204] Test time points: 0 minutes, 5 minutes, 10 minutes, 15 minutes, 20 minutes, 25 minutes, 30 minutes.

[0205] The test results are shown in the following table:

[0206]

[0207] As can be seen from the table above, the nicotine bag prepared in Example 1 exhibited significantly higher water absorption at all time points. For example, at 5 minutes, the water absorption of Example 1 was 15 mg, while that of Comparative Example 1 and Comparative Example 2 was 5 mg and 7 mg, respectively. This indicates that the modified fiber can absorb saliva faster, quickly reach a wet state, and improve the user's comfort when initially using the product.

[0208] At 30 minutes, the water absorption of Example 1 reached 50 mg, which is much higher than 18 mg of Comparative Example 1 and 30 mg of Comparative Example 2. Such high water absorption can ensure that the nicotine bag remains moist during the entire use process, prolong the effective use time, and reduce the feeling of dryness.

[0209] Through the comparison of the above water absorption data, we can clearly see the advantage of modified fiber in hydrophilicity. The modified fiber can absorb a large amount of saliva in a short time, ensuring that the nicotine bag remains moist within 30 minutes, extending the effective use time and reducing user discomfort.

[0210] 2. Nicotine release test (0-30 minutes)

[0211] Immersion in simulated saliva: The nicotine bags prepared in Example 1, Comparative Example 1 and Comparative Example 2 were immersed in simulated saliva respectively, and samples were taken regularly within 30 minutes to measure the nicotine concentration in the simulated saliva.

[0212] Nicotine release curve: Draw a curve of nicotine release (%) over time (nicotine release refers to the ratio of the amount of nicotine released by the nicotine bag to the amount of nicotine it originally contained), such as Figure 1 shown.

[0213] The test results are shown in the following table and Figure 1 As shown:

[0214]

[0215] From the above table and Figure 1It can be seen that the nicotine bag prepared in Example 1 showed significantly higher nicotine release at all time points. For example, at 5 minutes, the nicotine release of Example 1 reached 20%, while that of Comparative Example 1 and Comparative Example 2 was 8% and 12%, respectively. This shows that the modified fiber can absorb saliva faster, help nicotine to be released faster, and enhance the user's satisfaction when using the product for the first time.

[0216] At 30 minutes, the nicotine release of Example 1 reached 85%, which is much higher than 48% of Comparative Example 1 and 72% of Comparative Example 2. This means that users can obtain more nicotine in a shorter time, extend the effective use time of the nicotine bag, and reduce the problem of frequent replacement of nicotine bags.

[0217] The above comparison of nicotine release data clearly shows the advantages of modified fibers in nicotine release efficiency. Modified fibers can release a large amount of nicotine in a short period of time, which improves the user's initial satisfaction with the product. In addition, the maximum release of modified fibers is higher, ensuring that the nicotine bag releases most of the nicotine within 30 minutes, extending the effective use time and reducing user discomfort.

[0218] 3. Taste evaluation

[0219] The taste evaluation method is as follows: 10 professional tasters are selected, and they are not allowed to smoke, drink or eat food with strong odor 3 hours before the evaluation, so as not to affect the evaluation results. The nicotine bags prepared in Example 1 and Comparative Example 3 are placed between the inner side of the lower lip and the lower gum of the oral cavity, respectively. The nicotine bag placed in the lip each time is a small bag with a mass of 0.3g, and the standard consumption time is set to 15min; the head feeling, flavor, fragrance, odorlessness, wetness and smoothness of the nicotine bag are evaluated and scored with a full score of 5 points. The final results are shown in the following table with average scores:

[0220] sample Example 1 Comparative Example 3 Headache 4 3 Flavor 4 4 fragrance 5 3 No odor 5 3 Wetness 4 3 Smoothness 4 3

[0221] It can be seen from the above table that the nicotine bag prepared in Example 1 is superior to those in Comparative Example 3 in terms of head feeling, fragrance, odor-free property, wetness and smoothness. Since its wetness is higher than that in Comparative Example 3, nicotine is released faster and the head feeling is stronger. Moreover, the fragrance of Example 1 is brought by pure plant extracts, while the fragrance of Comparative Example 3 is brought by chemically synthesized flavors. The fragrance of pure plant extracts is fresher and more natural than that of chemically synthesized flavors, and can be better accepted by people.

[0222] The above are only specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto. Any person skilled in the art who is familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed by the present invention, which should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims

1. A method for preparing a flavor substance, characterized in that: The following steps are involved: S11: mixing rooibos tea, agave, and an extractant to obtain a mixture; S12: extracting the mixture so that the active substance of the rooibos tea and the active substance of the agave are dissolved in the extractant to obtain an extract; S13: Concentrating the extract to obtain the aromatic substance.

2. The method for preparing a flavor substance according to claim 1, characterized in that: In the above step S12, the mixture is extracted by at least one of a water bath heating extraction method, an ultrasonic extraction method and a high voltage pulse electric field extraction method.

3. The method for preparing a flavor substance according to claim 1, characterized in that: In the above step S12, the extract is a mixed solution obtained by mixing a plurality of groups of the mixtures after being extracted separately; Wherein, at least two groups of the mixtures are extracted by different methods, and / or at least two groups of the mixtures are extracted by different extractants.

4. The method for preparing a flavor substance according to claim 1, characterized in that: In the above step S11, the extractant includes at least one of water and ethanol solution, and the weight ratio of the rooibos tea, the agave and the extractant is (5-10): (3-8): (30-65).

5. The method for preparing a flavor substance according to any one of claims 1 to 4, characterized in that: In the above step S13, the extract is concentrated under low temperature and reduced pressure, and the temperature of the low temperature and reduced pressure concentration is controlled at 45°C to 55°C.

6. A flavoring substance, characterized in that: The aroma substance is prepared by the preparation method of the aroma substance according to any one of claims 1 to 5.

7. A nicotine oral product, characterized in that: The invention comprises a nicotine mixture, wherein the nicotine mixture comprises nicotine salt and flavor, and the flavor comprises the flavoring substance as claimed in claim 6.

8. The nicotine oral product according to claim 7, wherein: The nicotine mixture further comprises a filler, wherein the filler comprises modified fiber, and the modified fiber is obtained by attaching at least polycaprolactone and chitosan to the surface of plant fiber.

9. The nicotine oral product according to claim 8, characterized in that The rooibos tea and the agave form solid residues after extraction, and the plant fiber is prepared from the solid residues.

10. The nicotine oral product according to claim 8 or 9, characterized in that: The nicotine mixture comprises, by weight, 12-30 parts of nicotine salt, 3-10 parts of flavoring agent, 40-60 parts of filler, 0.1-2 parts of dispersant, 1-5 parts of pH regulator, 10-25 parts of wetting agent and 10-20 parts of flavor.

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