Magnetic resonance center frequency determination method and device, electronic equipment and storage medium

Abstract

The invention provides a magnetic resonance center frequency determination method and device, electronic equipment and a storage medium, and the method comprises the steps: carrying out the signal collection of a spin echo sequence and an inversion recovery sequence of a target tissue, and obtaining a spin echo signal and an inversion echo signal; carrying out wave crest data extraction on the spin echo signal to obtain spin wave crest data; and determining the magnetic resonance center frequency of the target tissue according to the spin wave crest data and the inversion echo signal. According to the magnetic resonance center frequency determination method, the center frequency is determined based on two echo signals including a spin echo signal and a reverse echo signal, the reverse echo signal can suppress a fat signal, and the spin echo signal collects an oil-water peak signal which does not suppress the fat signal. The magnetic resonance center frequency of the target tissue determined based on the two echo signals with different properties is more accurate.

Description

Technical Field

[0001] The present application relates to the field of magnetic resonance technology, and in particular to a method, device, electronic device and storage medium for determining a magnetic resonance center frequency. Background Art

[0002] In Magnetic Resonance Imaging (MRI), radio frequency pulses can be used to excite protons to resonate. When the vibration frequency of protons is the same as the center frequency of the radio frequency pulse, energy exchange can take place, and low-energy protons gain energy and enter a high-energy state, which is called nuclear magnetic resonance. The center frequency of the radio frequency pulse is an important parameter in magnetic resonance imaging. If the center frequency is inaccurate, it will directly lead to misalignment of the magnetic resonance image.

[0003] The prior art generally uses a single echo signal (eg, an inversion echo signal) to determine the center frequency of a magnetic resonance system, which has poor accuracy. Summary of the invention

[0004] In view of this, an object of the embodiments of the present application is to provide a method, device, electronic device and storage medium for determining a magnetic resonance center frequency, so as to solve the technical problem of poor accuracy of existing methods for determining a magnetic resonance center frequency.

[0005] In a first aspect, an embodiment of the present application provides a method for determining a magnetic resonance center frequency, the method for determining a magnetic resonance center frequency comprising:

[0006] Performing spin echo sequence signal acquisition on the target tissue to obtain a spin echo signal;

[0007] Performing an inversion recovery sequence signal acquisition on the target tissue to obtain an inversion echo signal;

[0008] Extracting peak data of the spin echo signal to obtain spin peak data;

[0009] The magnetic resonance center frequency of the target tissue is determined according to the spin peak data and the inversion echo signal.

[0010] In the above implementation process, the method for determining the magnetic resonance center frequency obtains spin echo signals and inversion echo signals by performing signal acquisition of the target tissue through a spin echo sequence and an inversion recovery sequence respectively; then extracts the peak data of the spin echo signal to obtain the spin peak data; and determines the magnetic resonance center frequency of the target tissue based on the spin peak data and the inversion echo signal. The method for determining the magnetic resonance center frequency determines the center frequency based on two echo signals, the spin echo signal and the inversion echo signal. Since the inversion echo signal can suppress the fat signal, and the spin echo signal acquires the oil-water peak signal that does not suppress the fat signal, the magnetic resonance center frequency of the target tissue determined based on these two echo signals of different properties is more accurate. This solves the technical problem of poor accuracy of the existing method for determining the magnetic resonance center frequency.

[0011] Optionally, in an embodiment of the present application, the spin peak data includes a spin peak frequency and a spin peak amplitude corresponding to each spin peak; determining the magnetic resonance center frequency of the target tissue based on the spin peak data and the inversion echo signal includes: determining a difference spectrum ratio based on the spin peak amplitude and the inversion echo signal amplitude corresponding to the spin peak frequency; wherein the difference spectrum ratio includes a ratio of an amplitude difference to the spin peak amplitude; the amplitude difference includes a difference between the spin peak amplitude of the same frequency and the inversion echo signal amplitude; and determining the magnetic resonance center frequency based on the difference spectrum ratio.

[0012] In the above implementation process, since the inversion echo signal can suppress the fat signal, and the spin echo signal collects the oil-water peak signal without suppressing the fat signal, the difference between the oil peak signal and the spin echo signal is larger, while the difference between the water peak signal is smaller. Based on the ratio of "the difference between the spin wave peak amplitude and the inversion echo signal amplitude of the same frequency" to the spin wave peak amplitude, the magnetic resonance center frequency of the target tissue can be determined more accurately.

[0013] Optionally, in an embodiment of the present application, determining the difference spectrum ratio based on the spin peak amplitude and the inversion echo signal amplitude corresponding to the spin peak frequency includes: selecting a preset number of quasi-spin peaks from the spin peaks according to the peak amplitudes; determining the difference spectrum ratio based on the quasi-spin peak amplitude of the quasi-spin peak and the inversion echo signal amplitude of the same frequency as the quasi-spin peak.

[0014] In the above implementation process, by selecting a preset number of quasi-spin peaks from the spin peaks according to the peak amplitude, the influence of the interference signal on the magnetic resonance center frequency can be reduced, and the accuracy of the determined "magnetic resonance center frequency of the target tissue" can be further improved.

[0015] Optionally, in an embodiment of the present application, determining the magnetic resonance center frequency based on the difference spectrum ratio includes: performing peak data extraction on the inversion echo signal to obtain inversion peak data; wherein the inversion peak data includes an inversion peak frequency corresponding to each inversion peak; determining the spin peak frequency corresponding to the minimum difference spectrum ratio as an intermediate magnetic resonance frequency; and in the presence of an inversion peak frequency consistent with the intermediate magnetic resonance frequency, determining the intermediate magnetic resonance frequency as the magnetic resonance center frequency.

[0016] In the above implementation process, the intermediate magnetic resonance frequency determined based on the difference spectrum ratio is verified according to the inversion peak data to ensure the accuracy of the determined "magnetic resonance center frequency of the target tissue".

[0017] Optionally, in an embodiment of the present application, after determining the spin peak frequency corresponding to the minimum difference spectrum ratio as the intermediate magnetic resonance frequency, determining the magnetic resonance center frequency of the target tissue based on the spin peak data and the inversion echo signal, further includes: in the absence of the inversion peak frequency consistent with the intermediate magnetic resonance frequency, determining the magnetic resonance center frequency based on the spin peak frequency.

[0018] In the above implementation process, in case of verification failure, the magnetic resonance center frequency of the target tissue is determined according to the spin peak frequency (peak frequency corresponding to the oil-water peak signal) to ensure the accuracy of the determined "magnetic resonance center frequency of the target tissue".

[0019] Optionally, in an embodiment of the present application, in the absence of the inversion peak frequency consistent with the intermediate magnetic resonance frequency, the magnetic resonance center frequency is determined according to the spin peak frequency, including: if the number of the spin peak frequencies is 1, the spin peak frequency is determined as the magnetic resonance center frequency; if the number of the spin peak frequencies is 2, the larger spin peak frequency is determined as the magnetic resonance center frequency; if the number of the spin peak frequencies is greater than or equal to 3, the larger spin peak frequency in the oil-water peak frequency group is determined as the magnetic resonance center frequency; wherein the oil-water peak frequency group includes two spin peak frequencies whose frequency difference is closest to the oil-water peak frequency difference.

[0020] In the above implementation process, since the water peak frequency is greater than the oil peak frequency, when the number of spin peak frequencies is 2, the larger spin peak frequency is determined as the magnetic resonance center frequency; when the number of spin peak frequencies is greater than or equal to 3, the larger frequency in the "oil-water peak frequency group whose two frequency differences are closest to the oil-water peak frequency difference" is determined as the magnetic resonance center frequency to ensure the accuracy of the determined "magnetic resonance center frequency of the target tissue".

[0021] Optionally, in an embodiment of the present application, when the number of the spin peaks is greater than 3, the preset number is 3.

[0022] In the above implementation process, by selecting three quasi-spin peaks from the spin peak according to the peak amplitude, the influence of the interference signal on the magnetic resonance center frequency can be reduced to a greater extent, and the accuracy of the determined "magnetic resonance center frequency of the target tissue" can be further improved.

[0023] In a second aspect, an embodiment of the present application further provides a device for determining a magnetic resonance center frequency, the device for determining a magnetic resonance center frequency comprising:

[0024] A spin echo acquisition module is used to acquire signals of a spin echo sequence of the target tissue to obtain a spin echo signal;

[0025] An inversion echo acquisition module, used for acquiring signals of an inversion recovery sequence for the target tissue to obtain an inversion echo signal;

[0026] A peak data extraction module, used for extracting peak data from the spin echo signal to obtain spin peak data;

[0027] The center frequency determination module is used to determine the magnetic resonance center frequency of the target tissue according to the spin peak data and the inversion echo signal.

[0028] Optionally, in an embodiment of the present application, the spin peak data includes a spin peak frequency and a spin peak amplitude corresponding to each spin peak; the center frequency determination module is specifically used to: determine a difference spectrum ratio according to the spin peak amplitude and an inversion echo signal amplitude corresponding to the spin peak frequency; wherein the difference spectrum ratio includes a ratio of an amplitude difference to the spin peak amplitude; the amplitude difference includes a difference between the spin peak amplitude and the inversion echo signal amplitude of the same frequency; and determine the magnetic resonance center frequency according to the difference spectrum ratio.

[0029] Optionally, in an embodiment of the present application, the center frequency determination module is further specifically used to: select a preset number of quasi-spin peaks from the spin peaks according to the peak amplitude; determine the difference spectrum ratio according to the quasi-spin peak amplitude of the quasi-spin peak and the amplitude of the inversion echo signal with the same frequency as the quasi-spin peak.

[0030] Optionally, in an embodiment of the present application, the center frequency determination module is further specifically used to: extract peak data from the inversion echo signal to obtain inversion peak data; wherein the inversion peak data includes an inversion peak frequency corresponding to each inversion peak; determine the spin peak frequency corresponding to the minimum difference spectrum ratio as an intermediate magnetic resonance frequency; and in the presence of an inversion peak frequency that is consistent with the intermediate magnetic resonance frequency, determine the intermediate magnetic resonance frequency as the magnetic resonance center frequency.

[0031] Optionally, in an embodiment of the present application, the center frequency determination module is further specifically used to: determine the magnetic resonance center frequency according to the spin peak frequency when there is no inversion peak frequency consistent with the intermediate magnetic resonance frequency.

[0032] Optionally, in an embodiment of the present application, the center frequency determination module is specifically used to: if the number of the spin peak frequencies is 1, determine the spin peak frequency as the magnetic resonance center frequency; if the number of the spin peak frequencies is 2, determine the larger spin peak frequency as the magnetic resonance center frequency; if the number of the spin peak frequencies is greater than or equal to 3, determine the larger spin peak frequency in the oil-water peak frequency group as the magnetic resonance center frequency; wherein the oil-water peak frequency group includes two spin peak frequencies whose frequency difference is closest to the oil-water peak frequency difference.

[0033] In a third aspect, an embodiment of the present application further provides an electronic device, comprising: a memory and a processor, wherein the memory stores a computer program executable by the processor, and when the computer program is executed by the processor, the method for determining the magnetic resonance center frequency as described in the first aspect above is performed.

[0034] In a fourth aspect, an embodiment of the present application further provides a computer-readable storage medium having computer program instructions stored thereon. When the computer program instructions are executed by a processor, the method for determining the magnetic resonance center frequency as described in the first aspect above is executed.

[0035] The present application provides a method, device, electronic device and storage medium for determining the center frequency of magnetic resonance. The target tissue is subjected to signal acquisition of a spin echo sequence and an inversion recovery sequence, respectively, to obtain a spin echo signal and an inversion echo signal. The spin echo signal is then subjected to peak data extraction to obtain spin peak data. The magnetic resonance center frequency of the target tissue is determined based on the spin peak data and the inversion echo signal. The method for determining the center frequency of magnetic resonance determines the center frequency based on two echo signals, the spin echo signal and the inversion echo signal. Since the inversion echo signal can suppress the fat signal, and the spin echo signal collects the oil-water peak signal that does not suppress the fat signal, the magnetic resonance center frequency of the target tissue determined based on these two echo signals of different properties is more accurate. This solves the technical problem of poor accuracy of the existing method for determining the center frequency of magnetic resonance. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments of the present application will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0037] Figure 1 A schematic diagram of a flow chart of a method for determining a magnetic resonance center frequency provided in an embodiment of the present application;

[0038] Figure 2 A schematic flow chart of a method for determining the magnetic resonance center frequency of a target tissue provided in an embodiment of the present application;

[0039] Figure 3 A waveform diagram of an echo signal provided in an embodiment of the present application;

[0040] Figure 4 A schematic diagram of the structure of a magnetic resonance center frequency determination device provided in an embodiment of the present application;

[0041] Figure 5 A schematic diagram of the structure of an electronic device provided in an embodiment of the present application. DETAILED DESCRIPTION

[0042] The following embodiments of the technical solution of the present application are described in detail in conjunction with the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present application, and are therefore only used as examples, and cannot be used to limit the scope of protection of the present application.

[0043] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by technicians in the technical field to which this application belongs; the terms used herein are only for the purpose of describing specific embodiments and are not intended to limit this application.

[0044] In the description of the embodiments of the present application, the technical terms "first", "second", etc. are only used to distinguish different objects, and cannot be understood as indicating or implying relative importance or implicitly indicating the number, specific order or primary and secondary relationship of the indicated technical features. In the description of the embodiments of the present application, the meaning of "multiple" is two or more, unless otherwise clearly and specifically defined.

[0045] See also Figure 1 The flowchart of a method for determining a magnetic resonance center frequency provided by an embodiment of the present application is shown. The method for determining a magnetic resonance center frequency may include the following steps:

[0046] Step 101, performing a spin echo sequence signal acquisition on the target tissue to obtain a spin echo signal;

[0047] Step 102, performing an inversion recovery sequence signal acquisition on the target tissue to obtain an inversion echo signal;

[0048] Step 103, extracting the peak data of the spin echo signal to obtain spin peak data;

[0049] Step 104: Determine the magnetic resonance center frequency of the target tissue according to the spin peak data and the inversion echo signal.

[0050] Wherein, in step 101, the target tissue may be the head, neck, spine, heart, lung, joint, abdominal pelvic cavity and blood vessels of the object to be examined. The object to be examined may be a human body or other animal body. A spin echo sequence refers to a pulse sequence in which a 90° pulse is first applied in MRI, then a 180° pulse is applied, and a free induction decay (FID) signal is detected. A spin echo signal refers to the waveform data of a spin echo collected based on a spin echo sequence (including the amplitude of the spin echo corresponding to each magnetic resonance frequency). The spin echo sequence does not attenuate the oil peak signal, and the collected spin echo signal is an oil-water peak signal without suppressing the fat signal.

[0051] Among them, in step 102, the inversion recovery sequence uses a 180° radio frequency pulse as an excitation pulse to flip the proton equilibrium magnetization vector in the selected plane by 180°, and adds a 90° detection pulse during the magnetization vector recovery period (relaxation process), and then detects a pulse sequence of the free induction decay (FID) signal. The inversion echo signal includes the waveform data of the collected inversion echo (including the amplitude of the inversion echo corresponding to each magnetic resonance frequency). The inversion recovery sequence mainly realizes the acquisition of fat suppression signals of the target tissue, and the oil peak signal in the collected inversion echo signal will be greatly attenuated, while the impact on the water peak signal is small.

[0052] Wherein, in step 103, the spin peak data includes the spin peak frequency and the spin peak amplitude corresponding to each spin peak; the spin peak data may also include the spin peak frequency, and the signal amplitude corresponding to each spin peak frequency may be determined according to the spin peak frequency and the spin echo signal.

[0053] Wherein, in step 104, the difference spectrum ratio may be determined according to the spin peak amplitude and the inversion echo signal amplitude corresponding to the spin peak frequency; and the magnetic resonance center frequency may be determined according to the difference spectrum ratio; wherein the difference spectrum ratio includes the ratio of the amplitude difference to the spin peak amplitude; and the amplitude difference includes the difference between the spin peak amplitude and the inversion echo signal amplitude of the same frequency. The amplitude difference may also be determined according to the spin peak amplitude and the inversion echo signal amplitude corresponding to the spin peak frequency; and the magnetic resonance center frequency may be determined according to the amplitude difference; wherein the amplitude difference includes the difference between the spin peak amplitude and the inversion echo signal amplitude of the same frequency.

[0054] It can be seen that the method for determining the magnetic resonance center frequency provided in the embodiment of the present application determines the center frequency through two echo signals, namely the spin echo signal and the inversion echo signal. Since the inversion echo signal can suppress the fat signal, and the spin echo signal collects the oil-water peak signal without suppressing the fat signal, the magnetic resonance center frequency of the target tissue determined based on these two echo signals of different properties is more accurate. This solves the technical problem of poor accuracy of the existing method for determining the magnetic resonance center frequency.

[0055] In addition, by using the magnetic resonance center frequency determination method provided in the present application, doctors can accurately determine the magnetic resonance center frequency of the target tissue to be imaged without having to input relevant information of the patient in advance, thereby improving the overall imaging efficiency.

[0056] Please refer to Figure 2 , Figure 2 A schematic flow chart of a method for determining the magnetic resonance center frequency of a target tissue provided in an embodiment of the present application.

[0057] In some optional embodiments, the spin peak data includes a spin peak frequency and a spin peak amplitude corresponding to each spin peak; step 104, determining the magnetic resonance center frequency of the target tissue according to the spin peak data and the inversion echo signal, including: step 1041, determining a difference spectrum ratio according to the spin peak amplitude and the inversion echo signal amplitude corresponding to the spin peak frequency; wherein the difference spectrum ratio includes a ratio of an amplitude difference to the spin peak amplitude; the amplitude difference includes a difference between the spin peak amplitude of the same frequency and the inversion echo signal amplitude; step 1042, determining the magnetic resonance center frequency according to the difference spectrum ratio.

[0058] Among them, the amplitude difference may be the absolute value of "the difference between the spin peak amplitude and the inversion echo signal amplitude of the same frequency", in which case the difference spectrum ratio may be "the ratio of the amplitude difference to the corresponding spin peak amplitude". Alternatively, the amplitude difference may be "the difference between the spin peak amplitude and the inversion echo signal amplitude of the same frequency", in which case the difference spectrum ratio may be the absolute value of "the ratio of the amplitude difference to the corresponding spin peak amplitude". The amplitude difference may be determined based on "the spin peak frequency and the spin peak amplitude corresponding to each spin peak" and the inversion echo signal. Specifically, the amplitude difference may be obtained by subtracting the spin peak amplitude corresponding to each spin peak frequency from the "amplitude of the inversion echo signal corresponding to the spin peak frequency". Taking the spin peak frequencies of 63.865 MHz and 63.872 MHz as an example, the spin peak amplitude corresponding to 63.865 MHz is subtracted from the “amplitude of the inversion echo signal corresponding to 63.865 MHz” to obtain the amplitude difference corresponding to the spin peak frequency of 63.865 MHz; the spin peak amplitude corresponding to 63.872 MHz is subtracted from the “amplitude of the inversion echo signal corresponding to 63.872 MHz” to obtain the amplitude difference corresponding to the spin peak frequency of 63.872 MHz.

[0059] The "spin peak frequency corresponding to the minimum difference spectrum ratio" can be determined as the magnetic resonance center frequency. The "spin peak frequency corresponding to the minimum difference spectrum ratio" can also be determined as the intermediate magnetic resonance frequency, and the intermediate magnetic resonance frequency is verified. If the verification is passed, the intermediate magnetic resonance frequency is determined as the magnetic resonance center frequency; if the verification is not passed, the magnetic resonance center frequency is determined according to the spin peak frequency.

[0060] In some optional embodiments, step 1041, determining the difference spectrum ratio according to the spin peak amplitude and the inversion echo signal amplitude corresponding to the spin peak frequency, includes: selecting a preset number of quasi-spin peaks from the spin peaks according to the peak amplitudes; determining the difference spectrum ratio according to the quasi-spin peak amplitude of the quasi-spin peak and the inversion echo signal amplitude of the same frequency as the quasi-spin peak.

[0061] The preset number may be 1, 3 or 5. The spin peaks may be sorted from large to small according to the peak amplitude, and a preset number of spin peaks with a higher order may be selected as quasi-spin peaks.

[0062] In some optional embodiments, step 1042, determining the magnetic resonance center frequency according to the difference spectrum ratio, includes: extracting peak data of the inversion echo signal to obtain inversion peak data; wherein the inversion peak data includes an inversion peak frequency corresponding to each inversion peak; determining the spin peak frequency corresponding to the minimum difference spectrum ratio as the intermediate magnetic resonance frequency; in the presence of an inversion peak frequency consistent with the intermediate magnetic resonance frequency, determining the intermediate magnetic resonance frequency as the magnetic resonance center frequency.

[0063] For example, the spin peak frequency corresponding to the minimum difference spectrum ratio is 63.872 MHz. At this time, the intermediate magnetic resonance frequency is 63.872 MHz. If the inversion peak frequency only includes 63.868 MHz and 63.865 MHz, it is considered that "there is no inversion peak frequency consistent with the intermediate magnetic resonance frequency"; if the inversion peak frequency includes 63.872 MHz and 63.868 MHz, it is considered that "there is an inversion peak frequency consistent with the intermediate magnetic resonance frequency". In the case where there is an inversion peak frequency within the frequency range determined based on the intermediate magnetic resonance frequency, it can be considered that "there is an inversion peak frequency consistent with the intermediate magnetic resonance frequency". Specifically, when the intermediate magnetic resonance frequency is 63.871 MHz, if there is an inversion peak frequency within the frequency range of 63.871±0.0001 MHz or 63.871±0.00005 MHz, it can be considered that "there is an inversion peak frequency consistent with the intermediate magnetic resonance frequency". The size of the specific frequency range can be adjusted according to the actual application.

[0064] Please refer to Figure 3 , Figure 3 A waveform diagram of an echo signal provided in an embodiment of the present application. Figure 3The horizontal axis of the waveform diagram of the echo signal shown represents the frequency point, and the vertical axis represents the signal strength obtained by Fourier transforming the original time domain signal, that is, the amplitude of the signal; wherein the initial frequency point 0 has an initial frequency value, and the initial frequency value may be 63.870MHz or 63.800MHz; the frequency difference between two adjacent frequency points may be a set value, for example, 12.5Hz, 50Hz or other reasonable values. Specifically, Figure 3 The initial frequency value is 63.870 MHz, the frequency difference between two adjacent frequency points is 12.5 Hz, and "there is an inversion peak frequency consistent with the intermediate magnetic resonance frequency", and Figure 3 The frequency point corresponding to the magnetic resonance center frequency of the target tissue determined according to the spin peak data and the inversion echo signal is 51, and accordingly, the magnetic resonance center frequency is 63.8706375 MHz.

[0065] In some optional embodiments, after the spin peak frequency corresponding to the minimum difference spectrum ratio is determined as the intermediate magnetic resonance frequency, step 1041, determining the magnetic resonance center frequency of the target tissue according to the spin peak data and the inversion echo signal, also includes: in the absence of the inversion peak frequency consistent with the intermediate magnetic resonance frequency, determining the magnetic resonance center frequency according to the spin peak frequency.

[0066] Among them, the spin echo sequence does not attenuate the oil peak signal, and the collected spin echo signal is an oil-water peak signal without suppressing the fat signal. In the case of "there is no inversion peak frequency consistent with the intermediate magnetic resonance frequency", it means that the collected inversion echo signal may have errors. At this time, the magnetic resonance center frequency is determined based on the spin peak frequency corresponding to the spin echo signal (oil-water peak signal), which can ensure the accuracy of the determined "magnetic resonance center frequency of the target tissue".

[0067] In some optional embodiments, in the absence of the inversion peak frequency consistent with the intermediate magnetic resonance frequency, the magnetic resonance center frequency is determined according to the spin peak frequency, including: if the number of the spin peak frequencies is 1, the spin peak frequency is determined as the magnetic resonance center frequency; if the number of the spin peak frequencies is 2, the larger spin peak frequency is determined as the magnetic resonance center frequency; if the number of the spin peak frequencies is greater than or equal to 3, the larger spin peak frequency in the oil-water peak frequency group is determined as the magnetic resonance center frequency; wherein the oil-water peak frequency group includes two spin peak frequencies whose frequency difference is closest to the oil-water peak frequency difference.

[0068] Among them, since the water peak frequency is greater than the oil peak frequency, by determining the larger spin peak frequency as the magnetic resonance center frequency when the number of spin peak frequencies is 2; and when the number of spin peak frequencies is greater than or equal to 3, determining the magnetic resonance center frequency as the larger frequency in the "oil-water peak frequency group whose two frequency differences are closest to the oil-water peak frequency difference", the accuracy of the determined "magnetic resonance center frequency of the target tissue" can be ensured. The oil-water peak frequency difference is determined according to the actual magnetic field strength of the magnetic resonance system. Magnetic resonance systems with different magnetic field strengths, for example, a 1.5T magnetic resonance system and a 3T magnetic resonance system, have different oil-water peak frequency differences.

[0069] In some optional embodiments, when the number of the spin peaks is greater than 3, the preset number is 3.

[0070] Among them, from Figure 3 As can be seen from the waveform diagram, the collected spin echo signal or inversion echo signal has interference signals. By selecting three quasi-spin peaks from the spin peak according to the peak amplitude, the influence of the interference signal on the determined magnetic resonance center frequency can be greatly reduced.

[0071] Please refer to Figure 4 , Figure 4 A schematic diagram of the structure of a magnetic resonance center frequency determination device provided in an embodiment of the present application. The magnetic resonance center frequency determination device comprises:

[0072] The spin echo acquisition module 201 is used to acquire the signal of the spin echo sequence of the target tissue to obtain the spin echo signal;

[0073] An inversion echo acquisition module 202 is used to acquire signals of the target tissue using an inversion recovery sequence to obtain an inversion echo signal;

[0074] A peak data extraction module 203 is used to extract the peak data of the spin echo signal to obtain spin peak data;

[0075] The center frequency determination module 204 is used to determine the magnetic resonance center frequency of the target tissue according to the spin peak data and the inversion echo signal.

[0076] It should be understood that the magnetic resonance center frequency determination device corresponds to the above-mentioned magnetic resonance center frequency determination method embodiment, and can perform the various steps involved in the above-mentioned method embodiment. The specific functions of the magnetic resonance center frequency determination device can be found in the above description. To avoid repetition, the detailed description is appropriately omitted here. The magnetic resonance center frequency determination device includes at least one software function module that can be stored in a memory in the form of software or firmware or solidified in the operating system (OS) of the device.

[0077] Please refer to Figure 5 , Figure 5 A schematic diagram of the structure of an electronic device provided in an embodiment of the present application. An electronic device 300 provided in an embodiment of the present application includes: a processor 301 and a memory 302, and these components are interconnected and communicate with each other through a communication bus 303 and / or other forms of connection mechanisms (not shown). The memory 302 stores a computer program executable by the processor 301, and when the computer program is executed by the processor 301, the above method for determining the center frequency of magnetic resonance is executed.

[0078] The embodiment of the present application further provides a computer-readable storage medium, on which computer program instructions are stored. When the computer program instructions are executed by the processor 301, the above method for determining the magnetic resonance center frequency is executed.

[0079] Among them, the storage medium can be implemented by any type of volatile or non-volatile storage device or a combination thereof, such as static random access memory (SRAM), electrically erasable programmable read-only memory (EEPROM), erasable programmable read-only memory (EPROM), programmable red-only memory (PROM), read-only memory (ROM), magnetic storage, flash memory, disk or optical disk.

[0080] In several embodiments provided by the embodiments of the present application, it should be understood that the disclosed devices and methods can also be implemented in other ways. The device embodiments described above are merely schematic. For example, the flowcharts and block diagrams in the accompanying drawings show the possible architecture, functions and operations of the devices, methods and computer program products according to the multiple embodiments of the embodiments of the present application. In this regard, each box in the flowchart or block diagram can represent a module, a program segment or a part of the code, and a part of the module, program segment or code contains one or more executable instructions for implementing the specified logical function. It should also be noted that in some alternative implementations, the functions marked in the box can also occur in a different order than the order marked in the accompanying drawings. For example, two consecutive boxes can actually be executed substantially in parallel, and they can sometimes be executed in the opposite order, depending on the functions involved. It should also be noted that each box in the block diagram and / or flowchart, and the combination of boxes in the block diagram and / or flowchart can be implemented with a dedicated hardware-based system that performs a specified function or action, or can be implemented with a combination of dedicated hardware and computer instructions.

[0081] In addition, the functional modules in each embodiment of the present application can be integrated together to form an independent part, or each module can exist separately, or two or more modules can be integrated to form an independent part.

[0082] The above description is only an optional implementation manner of the embodiments of the present application, but the protection scope of the embodiments of the present application is not limited thereto. Any technician familiar with the technical field can easily think of changes or replacements within the technical scope disclosed in the embodiments of the present application, which should be covered within the protection scope of the embodiments of the present application.

Claims

1. A method for determining a magnetic resonance center frequency, characterized in that: The method comprises: Performing signal acquisition of a spin echo sequence on the target tissue to obtain a spin echo signal; Performing an inversion recovery sequence signal acquisition on the target tissue to obtain an inversion echo signal; Extracting peak data of the spin echo signal to obtain spin peak data; The magnetic resonance center frequency of the target tissue is determined according to the spin peak data and the inversion echo signal.

2. The method according to claim 1, characterized in that in, The spin peak data includes a spin peak frequency and a spin peak amplitude corresponding to each spin peak; Determining the magnetic resonance center frequency of the target tissue according to the spin peak data and the inversion echo signal includes: Determine a difference spectrum ratio according to the spin peak amplitude and the inversion echo signal amplitude corresponding to the spin peak frequency; wherein the difference spectrum ratio includes a ratio of the amplitude difference to the spin peak amplitude; and the amplitude difference includes a difference between the spin peak amplitude and the inversion echo signal amplitude of the same frequency; The magnetic resonance center frequency is determined according to the difference spectrum ratio.

3. The method according to claim 2, characterized in that Determining the difference spectrum ratio according to the spin peak amplitude and the inversion echo signal amplitude corresponding to the spin peak frequency includes: Selecting a preset number of quasi-spin peaks from the spin peaks according to the peak amplitudes; The difference spectrum ratio is determined according to the quasi-spin peak amplitude of the quasi-spin peak and the amplitude of the inversion echo signal with the same frequency as the quasi-spin peak.

4. The method according to claim 2, characterized in that: The determining the magnetic resonance center frequency according to the difference spectrum ratio comprises: Extracting the peak data of the inversion echo signal to obtain inversion peak data; wherein the inversion peak data includes the inversion peak frequency corresponding to each inversion peak; Determining the spin peak frequency corresponding to the minimum difference spectrum ratio as the intermediate magnetic resonance frequency; When the inversion peak frequency coincides with the intermediate magnetic resonance frequency, the intermediate magnetic resonance frequency is determined as the magnetic resonance center frequency.

5. The method according to claim 4, characterized in that After determining the spin peak frequency corresponding to the minimum difference spectrum ratio as the intermediate magnetic resonance frequency, determining the magnetic resonance center frequency of the target tissue according to the spin peak data and the inversion echo signal, further includes: In the absence of the inversion peak frequency that coincides with the intermediate magnetic resonance frequency, the magnetic resonance center frequency is determined based on the spin peak frequency.

6. The method according to claim 5, characterized in that The determining the magnetic resonance center frequency according to the spin peak frequency in the absence of the inversion peak frequency consistent with the intermediate magnetic resonance frequency comprises: If the number of the spin peak frequencies is 1, determining the spin peak frequency as the magnetic resonance center frequency; If the number of the spin peak frequencies is 2, the larger spin peak frequency is determined as the magnetic resonance center frequency; If the number of the spin peak frequencies is greater than or equal to 3, the larger spin peak frequency in the oil-water peak frequency group is determined as the magnetic resonance center frequency; wherein the oil-water peak frequency group includes two spin peak frequencies whose frequency difference is closest to the oil-water peak frequency difference.

7. The method according to claim 3, characterized in that in, When the number of the spin peaks is greater than 3, the preset number is 3.

8. A device for determining a magnetic resonance center frequency, characterized in that: The device comprises: A spin echo acquisition module is used to acquire signals of a spin echo sequence of the target tissue to obtain a spin echo signal; An inversion echo acquisition module, used for acquiring signals of an inversion recovery sequence for the target tissue to obtain an inversion echo signal; A peak data extraction module, used for extracting peak data from the spin echo signal to obtain spin peak data; The center frequency determination module is used to determine the magnetic resonance center frequency of the target tissue according to the spin peak data and the inversion echo signal.

9. An electronic device, characterized in that: The electronic device comprises: Memory; processor; The memory stores a computer program executable by the processor, and when the computer program is executed by the processor, the method according to any one of claims 1 to 7 is performed.

10. A computer-readable storage medium, characterized in that: The computer-readable storage medium stores computer program instructions, and when the computer program instructions are executed by a processor, the method according to any one of claims 1 to 7 is executed.

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