Gastroesophageal acid exposure degree analysis method, device and equipment and storage medium

Abstract

The invention discloses a gastroesophageal acid exposure degree analysis method, device and equipment and a storage medium, and relates to the field of gastroesophageal PH data analysis. The method comprises the following steps: acquiring all acid exposure curve segments in a PH data curve corresponding to gastroesophageal PH monitoring; obtaining an acid exposure area according to an area formed between the acid exposure curve segment and an acid exposure PH threshold value, and summing the acid exposure areas corresponding to all the acid exposure curve segments to obtain a total acid exposure area; analyzing the acid exposure degree according to the total acid exposure area; wherein the total acid exposure area is in direct proportion to the acid exposure degree. The acid exposure degree is analyzed through the acid exposure areas corresponding to all the acid exposure curve sections in the PH data curve and the total acid exposure area obtained through summation, the acid exposure degree is used for assisting illness degree analysis, and symptoms of patients with the same acid exposure time percentage can be distinguished.

Description

Technical Field

[0001] The present invention relates to the field of gastroesophageal pH data analysis, and in particular to a gastroesophageal acid exposure degree analysis method, device, equipment and storage medium. Background Art

[0002] Gastroesophageal reflux disease (GERD) refers to a disease in which gastric contents reflux into the esophagus, causing discomfort and / or complications. GERD is usually detected by 24-hour impedance-pH (acidity, PondusHydrogenii) monitoring, pH capsule 48 / 96-hour monitoring, etc., and the condition is analyzed based on the percentage of acid exposure time (AET, Acid Exposure Time) (acid exposure time refers to the time when the esophageal pH value is <4 within 24 hours, and the acid exposure time percentage refers to the percentage of time when the esophageal pH value is <4 within 24 hours). However, the acid exposure time can only reflect the acid exposure state within a certain period of time, and cannot realize the acid exposure degree analysis, that is, the severity of the disease cannot be analyzed based on the acid exposure time. Summary of the invention

[0003] In view of this, the purpose of the present invention is to provide a method, device, equipment and storage medium for analyzing the degree of gastroesophageal acid exposure, which can use the degree of acid exposure to assist in the analysis of the degree of disease and differentiate the symptoms of patients with the same percentage of acid exposure time. The specific scheme is as follows:

[0004] In a first aspect, the present application discloses a method for analyzing gastroesophageal acid exposure, comprising:

[0005] Obtain all acid exposure curve segments in the pH data curve corresponding to gastroesophageal pH monitoring;

[0006] The acid exposure area is obtained according to the area formed between the acid exposure curve segment and the acid exposure pH threshold, and the total acid exposure area is obtained by summing the acid exposure areas corresponding to all acid exposure curve segments;

[0007] The degree of acid exposure is analyzed based on the total acid exposure area; wherein the total acid exposure area is proportional to the degree of acid exposure.

[0008] Optionally, obtaining the acid exposure area according to the area formed between the acid exposure curve segment and the acid exposure pH threshold comprises:

[0009] Dividing the acid exposure curve segment into a plurality of small intervals of equal duration according to a preset duration;

[0010] Obtaining a pH difference according to a difference between the pH value corresponding to the small interval and the acid exposure pH threshold;

[0011] According to the product of the pH difference corresponding to the small interval and the preset time length, the acid exposure sub-area corresponding to the small interval is obtained;

[0012] The acid exposure area is obtained by summing the acid exposure sub-areas corresponding to all small intervals in the acid exposure curve segment and obtaining the area between the acid exposure curve segment and the acid exposure pH threshold.

[0013] Optionally, analyzing the degree of acid exposure according to the total acid exposure area includes:

[0014] If the total acid exposure area is greater than a first preset area threshold, it is determined to be acid exposure abnormality;

[0015] If the total acid exposure area is less than the first preset area threshold and greater than the second preset area threshold, it is determined to be a suspected acid exposure abnormality; the first preset area threshold is greater than the second preset area threshold;

[0016] If the total acid exposure area is smaller than the second preset area threshold, it is determined that the acid exposure is normal.

[0017] Optionally, the gastroesophageal acid exposure degree analysis method further comprises:

[0018] Dividing the acid exposure curve segment into a plurality of small intervals of equal duration according to a preset duration;

[0019] Determine the acid exposure sub-area corresponding to each of the small areas, calculate the sub-area difference of the acid exposure sub-areas between all adjacent small areas, and obtain the total area difference by summing all the sub-area differences;

[0020] The acid clearance capacity is analyzed based on the total area difference; the total area difference is proportional to the acid clearance capacity.

[0021] Optionally, the calculating of the sub-area differences of the acid exposure sub-areas between all adjacent sub-areas and obtaining a total area difference by summing up all the sub-area differences comprises:

[0022] Calculate the absolute value of the difference in acid exposure sub-areas between two adjacent small areas to obtain the sub-area difference between the adjacent small areas;

[0023] According to the sub-area differences corresponding to all small intervals under the acid exposure curve segment, the area difference corresponding to the acid exposure curve segment is obtained;

[0024] The total area difference is obtained by summing up the area differences corresponding to all the acid exposure curve segments.

[0025] Optionally, the calculating of the sub-area differences of the acid exposure sub-areas between all adjacent sub-areas includes:

[0026] Deleting the first small interval and the last small interval of each of the acid exposure curve segments to obtain an updated acid exposure curve segment;

[0027] The sub-area differences of the acid exposure sub-areas between all adjacent small intervals in all the small intervals of the updated acid exposure curve segments are calculated.

[0028] Optionally, analyzing the acid clearance capacity according to the total area difference comprises:

[0029] If the total area difference is greater than a first preset area difference threshold, it is determined that the acid clearance ability is strong;

[0030] If the total area difference is less than the first preset area difference threshold and greater than the second preset area difference threshold, it is determined that the acid clearance capacity is average; the first preset area difference threshold is greater than the second preset area difference threshold;

[0031] If the total area difference is less than the second preset area difference threshold, it is determined that the acid clearance ability is weak.

[0032] In a second aspect, the present application discloses a gastroesophageal acid exposure degree analysis device, comprising:

[0033] An acid exposure curve segment acquisition module, used to acquire all acid exposure curve segments in the pH data curve corresponding to gastroesophageal pH monitoring;

[0034] an acid exposure total area determination module, configured to obtain the acid exposure area according to the area formed between the acid exposure curve segment and the acid exposure pH threshold, and obtain the acid exposure total area by summing the acid exposure areas corresponding to all acid exposure curve segments;

[0035] The acid exposure degree analysis module is used to analyze the acid exposure degree according to the total acid exposure area; wherein the total acid exposure area is proportional to the acid exposure degree.

[0036] In a third aspect, the present application discloses an electronic device, comprising:

[0037] Memory, used to store computer programs;

[0038] A processor is used to execute the computer program to implement the aforementioned gastroesophageal acid exposure degree analysis method.

[0039] In a fourth aspect, the present application discloses a computer-readable storage medium for storing a computer program; wherein the computer program, when executed by a processor, implements the aforementioned gastroesophageal acid exposure degree analysis method.

[0040] In the present application, all acid exposure curve segments in the PH data curve corresponding to gastroesophageal PH monitoring are obtained; the acid exposure area is obtained according to the area formed between the acid exposure curve segment and the acid exposure PH threshold, and the total acid exposure area is obtained by summing the acid exposure areas corresponding to all acid exposure curve segments; the degree of acid exposure is analyzed according to the total acid exposure area; wherein the total acid exposure area is proportional to the degree of acid exposure. It can be seen that the acid exposure area is obtained by calculating the graphic area enclosed by the acid exposure curve segment and the acid exposure PH threshold in a two-dimensional plane. Since the period when the pH value is lower than the acid exposure PH threshold is the acid exposure time, the larger the acid exposure area, the lower the pH value on the acid exposure curve segment. Therefore, the degree of acid exposure is analyzed by summing the acid exposure areas corresponding to all acid exposure curve segments in the PH data curve, and the degree of acid exposure is used to assist in the analysis of the degree of illness, so that the symptoms of patients with the same percentage of acid exposure time can be distinguished. BRIEF DESCRIPTION OF THE DRAWINGS

[0041] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying creative work.

[0042] Figure 1 A flow chart of a method for analyzing gastroesophageal acid exposure provided in this application;

[0043] Figure 2 A schematic diagram of a specific acid exposure curve segment provided for this application;

[0044] Figure 3 Another specific acid exposure curve segment schematic diagram provided for this application;

[0045] Figure 4 A specific schematic diagram of the acid exposure area provided for this application;

[0046] Figure 5 A flow chart of a specific gastroesophageal acid exposure analysis method provided in this application;

[0047] Figure 6 Another specific acid exposure curve segment schematic diagram provided for this application;

[0048] Figure 7 A schematic diagram of the structure of a gastroesophageal acid exposure degree analysis device provided in this application;

[0049] Figure 8 A structural diagram of an electronic device provided for this application. DETAILED DESCRIPTION

[0050] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0051] In the prior art, the condition is analyzed based on the percentage of acid exposure time. However, the acid exposure time can only reflect the acid exposure state within a certain period of time, and cannot realize the acid exposure degree analysis, that is, it is impossible to analyze the severity of the condition based on the acid exposure time. In order to overcome the above technical problems, the present application proposes an esophageal acid exposure degree analysis method, which can use the acid exposure degree to assist the condition severity analysis and distinguish the symptoms of patients with the same acid exposure time percentage.

[0052] The present application discloses a method for analyzing the degree of gastroesophageal acid exposure. Figure 1 As shown, the method may include the following steps:

[0053] Step S11: Acquire all acid exposure curve segments in the pH data curve corresponding to gastroesophageal pH monitoring.

[0054] First, all acid exposure curve segments in the PH data curve corresponding to gastroesophageal PH monitoring are obtained. The PH data curve is a curve of PH change over time corresponding to the entire gastroesophageal PH monitoring process, which can be 24 / 48 / 72 / 96 hours of monitoring. This embodiment does not limit the monitoring time and method. The PH curve corresponding to the period when the PH value in the PH data curve is lower than 4 is the acid exposure curve segment.

[0055] Step S12: obtaining an acid exposure area according to the area formed between the acid exposure curve segment and the acid exposure pH threshold, and obtaining a total acid exposure area by summing up the acid exposure areas corresponding to all acid exposure curve segments.

[0056] After the acid exposure curve segment is obtained, the acid exposure area of ​​the acid exposure curve segment is obtained according to the area enclosed by the acid exposure curve segment and the acid exposure pH threshold in two dimensions, and the total acid exposure area is obtained according to the sum of the acid exposure areas corresponding to all acid exposure curve segments.

[0057] For example Figure 1 and Figure 2 The specific acid exposure curve segment shown is schematically shown in FIG. Figure 1 and Figure 2 The acid exposure time R is equal to R = R2-R1. When R is the same, Figure 1 and Figure 2 The same GERD symptoms may be considered to be present in different situations, leading to a judgment that the GERD symptoms are the same. Figure 1 It is just a minor fall and the patient may only experience mild discomfort; Figure 2 The patient's condition is more serious due to the deep fall, so it cannot be analyzed based on the acid exposure time; that is, even if the acid exposure time percentage is the same, the severity of gastroesophageal reflux in the patient is different. Therefore, this application analyzes by the total acid exposure area; by calculating the acid exposure area, Figure 2 The corresponding acid exposure area is significantly smaller than Figure 3 Corresponding garlic exposure area.

[0058] In some embodiments, the acid exposure area is obtained according to the area formed between the acid exposure curve segment and the acid exposure pH threshold, which may include: dividing the acid exposure curve segment into a plurality of small intervals of the same duration according to a preset duration; obtaining a pH difference according to the difference between the pH value corresponding to the small interval and the acid exposure pH threshold; obtaining an acid exposure sub-area corresponding to the small interval according to the product of the pH difference corresponding to the small interval and the preset duration; obtaining the acid exposure area according to the sum of the acid exposure sub-areas corresponding to all small intervals in the acid exposure curve segment, and obtaining the area between the acid exposure curve segment and the acid exposure pH threshold. That is, the acid exposure area is calculated by calculus, for example Figure 4 As shown in the figure, the acid exposure time R1-R2 is sufficiently subdivided to obtain multiple small intervals of t0, t1, ... tn. The time period represented by each small interval is the same, which is △t. Then the acid exposure sub-area corresponding to the first small interval is Figure 4 The rectangle formed by (t0, t1, p1, p0) is deduced in this way (t1, t2, p2, p1) ..... (tn-1, tn, pn, pn-1) to form n rectangles. The area of ​​each rectangle △s is an acid exposure sub-area. The n acid exposure sub-areas are accumulated in sequence to form a differential area ∑s=△s1+△s2+...+△sn, which is the acid exposure area. A case consists of multiple acid exposure intervals. The differential areas are calculated according to the same algorithm, and then the total acid exposure area is obtained by summing them up, which is recorded as CR.

[0059] Step S13: analyzing the degree of acid exposure according to the total acid exposure area; wherein the total acid exposure area is proportional to the degree of acid exposure.

[0060] In this embodiment, the acid exposure degree is analyzed based on the calculated total acid exposure area. The total acid exposure area is proportional to the acid exposure degree, that is, the larger the total acid exposure area, the higher the total area and the acid exposure degree, and the smaller the total acid exposure area, the lower the total area and the acid exposure degree; that is, the larger the CR, the greater the acid exposure degree, and the smaller the CR, the smaller the acid exposure degree.

[0061] In some embodiments, analyzing the degree of acid exposure based on the total acid exposure area may include: if the total acid exposure area is greater than a first preset area threshold, it is determined that the acid exposure is abnormal; if the total acid exposure area is less than the first preset area threshold and greater than a second preset area threshold, it is determined that the acid exposure is suspected to be abnormal; the first preset area threshold is greater than the second preset area threshold; if the total acid exposure area is less than the second preset area threshold, it is determined that the acid exposure is normal. That is, a range threshold (C1 - C2) can be set for CR; if CR > C2, it is considered that the degree of acid exposure is severe; if CR < C1, it is considered that the degree of acid exposure is acceptable; if CR ∈ (C1, C2), it is considered that the degree of acid exposure is in the suspected range.

[0062] As can be seen from the above, in this embodiment, all acid exposure curve segments in the PH data curve corresponding to the gastroesophageal PH monitoring are obtained; the acid exposure area is obtained based on the area formed between the acid exposure curve segment and the acid exposure PH threshold, and the total acid exposure area is obtained by summing the acid exposure areas corresponding to all acid exposure curve segments; the degree of acid exposure is analyzed based on the total acid exposure area; wherein, the total acid exposure area is proportional to the degree of acid exposure. It can be seen that by calculating the area of the figure enclosed by the acid exposure curve segment and the acid exposure PH threshold in the two-dimensional plane, the acid exposure area is obtained. Since the time period when the PH value is lower than the acid exposure PH threshold is the acid exposure time, the larger the above-mentioned acid exposure area, the lower the PH value on the acid exposure curve segment. Therefore, by analyzing the degree of acid exposure based on the total acid exposure area obtained by summing the acid exposure areas corresponding to all acid exposure curve segments in the PH data curve, and using the degree of acid exposure to assist in analyzing the degree of the disease, the symptoms of patients with the same percentage of acid exposure time can be distinguished.

[0063] An embodiment of the present application discloses a specific method for analyzing the degree of gastroesophageal acid exposure. Refer to Figure 5 As shown, this method may include the following steps:

[0064] Step S21: Obtain all acid exposure curve segments in the PH data curve corresponding to the gastroesophageal PH monitoring.

[0065] Step S22: Divide the acid exposure curve segment into multiple small intervals with the same duration according to a preset duration.

[0066] Step S23: Determine the acid exposure sub-area corresponding to each small interval, calculate the sub-area difference between the acid exposure sub-areas of all adjacent small intervals, and obtain the total area difference by summing all the sub-area differences.

[0067] It can be understood that Figure 2 if it quickly rebounds after the deep fall as shown, it indicates that the patient has a strong acid clearance ability; Figure 6If the acid level drops deeply and does not rise again for a long time, it indicates that the acid clearance capacity is weak, which will lead to more severe GERD symptoms. Therefore, in order to further improve the accuracy of symptom analysis, the acid clearance capacity is analyzed by analyzing the acid exposure curve segment. Figure 6 As shown in Figure 1, it has been in a deep drop state. During the drop period, the pH value has almost no change, and the difference between the acid exposure sub-areas between two adjacent small areas has not changed much. Figure 4 , then it rises again after falling, the pH value changes greatly, and the corresponding difference between the acid exposure sub-areas of two adjacent small areas is also large. Then the cumulative sum of the absolute values ​​of the difference △s between the acid exposure sub-areas of two adjacent small areas ∑fs=|△s2-△s1|+....+|△sn-△sn-1| can be used as an indicator to judge the acid clearance capacity, recorded as CDR.

[0068] In some embodiments, the sub-area difference of the acid exposure sub-area between all adjacent small cells is calculated, and the total area difference is obtained by summing up all the sub-area differences, which may include: calculating the absolute value of the difference of the acid exposure sub-area between two adjacent small cells to obtain the sub-area difference between adjacent small cells; obtaining the area difference corresponding to the acid exposure curve segment according to the sub-area differences corresponding to all small cells under the acid exposure curve segment; and summing up the area differences corresponding to all the acid exposure curve segments to obtain the total area difference. It can be understood that the larger the sub-area difference between adjacent small cells, the greater the pH change amplitude, that is, the stronger the acid clearance ability.

[0069] In some embodiments, calculating the sub-area differences of the acid exposure sub-areas between all adjacent small intervals may include: deleting the first small interval and the last small interval of each of the acid exposure curve segments to obtain an updated acid exposure curve segment; calculating the sub-area differences of the acid exposure sub-areas between all adjacent small intervals in the small intervals of all the updated acid exposure curve segments.

[0070] In order to make the parameter more accurate, consider removing the first small interval at the entrance of R1 and the last small interval at the exit of R2. This can eliminate the influence of the rapid drop in pH at the entrance and the rapid rise in pH at the exit. The total area difference ∑fs=|△s3-△s2|+....+|△sn-1-△sn-2|.

[0071] Step S24: analyzing the acid clearance capacity according to the total area difference; the total area difference is proportional to the acid clearance capacity.

[0072] In this embodiment, analyzing the acid clearance ability based on the total area difference includes: if the total area difference is greater than the first preset area difference threshold, it is determined that the acid clearance ability is strong; if the total area difference is less than the first preset area difference threshold and greater than the second preset area difference threshold, it is determined that the acid clearance ability is average; the first preset area difference threshold is greater than the second preset area difference threshold; if the total area difference is less than the second preset area difference threshold, it is determined that the acid clearance ability is weak. That is, the larger the CDR, the greater the acid clearance ability; the smaller the CDR, the smaller the acid clearance ability. Specifically, a range threshold (D1 - D2) can be set for CDR. If CDR > D2, it is considered that the acid clearance ability is relatively strong; if CDR < C1, it is considered that the acid clearance ability is relatively weak; if CDR ∈ (D1, D2), it is considered that the acid clearance ability is in a suspected interval.

[0073] Among them, for the specific processes of the above steps S21 and S22, reference can be made to the corresponding content disclosed in the foregoing embodiments, and details will not be elaborated here.

[0074] As can be seen from the above, in this embodiment, the acid exposure curve segment is divided into multiple small intervals with the same duration according to the preset duration; the acid exposure sub - area corresponding to each small interval is determined, the sub - area difference between the acid exposure sub - areas of all adjacent small intervals is calculated, and the total area difference is obtained by summing all the sub - area differences; the acid clearance ability is analyzed based on the total area difference; the total area difference is proportional to the acid clearance ability. The judgment of the acid clearance ability is realized, and the diagnostic accuracy is improved. Under the condition that the percentage of acid exposure time is the same, the acid exposure degree and acid clearance ability of the patient can be judged more accurately to assist in diagnosis.

[0075] Correspondingly, an embodiment of the present application also discloses a device for analyzing the degree of gastroesophageal acid exposure. Refer to Figure 7 as shown. The device includes:

[0076] An acid exposure curve segment acquisition module 11, configured to acquire all acid exposure curve segments in the PH data curve corresponding to the gastroesophageal PH monitoring;

[0077] An acid exposure total area determination module 12, configured to obtain the acid exposure area according to the area formed between the acid exposure curve segment and the acid exposure PH threshold, and obtain the total acid exposure area by summing the acid exposure areas corresponding to all acid exposure curve segments;

[0078] An acid exposure degree analysis module 13, configured to analyze the acid exposure degree according to the total acid exposure area; wherein, the total acid exposure area is proportional to the acid exposure degree.

[0079] As can be seen from the above, in this embodiment, all acid exposure curve segments in the PH data curve corresponding to gastroesophageal PH monitoring are obtained; the acid exposure area is obtained according to the area formed between the acid exposure curve segment and the acid exposure PH threshold, and the total acid exposure area is obtained by summing the acid exposure areas corresponding to all acid exposure curve segments; the degree of acid exposure is analyzed according to the total acid exposure area; wherein the total acid exposure area is proportional to the degree of acid exposure. It can be seen that the acid exposure area is obtained by calculating the area of ​​the figure enclosed by the acid exposure curve segment and the acid exposure PH threshold in a two-dimensional plane. Since the period when the PH value is lower than the acid exposure PH threshold is the acid exposure time, the larger the above acid exposure area, the lower the PH value on the acid exposure curve segment. Therefore, the degree of acid exposure is analyzed by summing the acid exposure areas corresponding to all acid exposure curve segments in the PH data curve, and the degree of acid exposure is used to assist in the analysis of the degree of illness, so that the symptoms of patients with the same percentage of acid exposure time can be distinguished.

[0080] In some specific embodiments, the acid exposure total area determination module 12 may specifically include:

[0081] A partitioning unit, used for dividing the acid exposure curve segment into a plurality of small intervals with the same duration according to a preset duration;

[0082] A pH difference determination unit, configured to obtain a pH difference according to a difference between the pH value corresponding to the small interval and the acid exposure pH threshold;

[0083] An exposure sub-area determination unit, configured to obtain the acid exposure sub-area corresponding to the small interval according to the product of the pH difference corresponding to the small interval and the preset time length;

[0084] The acid exposure area determination unit is used to obtain the acid exposure area by obtaining the area between the acid exposure curve segment and the acid exposure pH threshold value according to the sum of the acid exposure sub-areas corresponding to all small intervals in the acid exposure curve segment.

[0085] In some specific embodiments, the acid exposure degree analysis module 13 may specifically include:

[0086] an acid exposure abnormality determination unit, configured to determine that the acid exposure is abnormal if the total acid exposure area is greater than a first preset area threshold;

[0087] a suspected acid exposure abnormality determination unit, configured to determine that the acid exposure total area is a suspected acid exposure abnormality if the acid exposure total area is less than the first preset area threshold and greater than a second preset area threshold; and the first preset area threshold is greater than the second preset area threshold;

[0088] The acid exposure normal determination unit is used to determine that the acid exposure is normal if the total acid exposure area is smaller than the second preset area threshold.

[0089] In some specific embodiments, the gastroesophageal acid exposure degree analysis device may further include:

[0090] A partitioning unit, used for dividing the acid exposure curve segment into a plurality of small intervals with the same duration according to a preset duration;

[0091] a total area difference determination unit, configured to determine the acid exposure sub-area corresponding to each of the small cells, calculate the sub-area differences of the acid exposure sub-areas between all adjacent small cells, and obtain the total area difference by summing up all the sub-area differences;

[0092] The acid clearance capacity analysis unit is used to analyze the acid clearance capacity according to the total area difference; the total area difference is proportional to the acid clearance capacity.

[0093] In some specific embodiments, the total area difference determining unit may specifically include:

[0094] A sub-area difference determination unit, used to calculate the absolute value of the difference in acid exposure sub-areas between two adjacent small cells to obtain the sub-area difference between the adjacent small cells;

[0095] An area difference determination unit, configured to obtain an area difference corresponding to the acid exposure curve segment according to the sub-area differences corresponding to all small intervals under the acid exposure curve segment;

[0096] The total area difference determination unit is used to obtain the total area difference by summing up the area differences corresponding to all the acid exposure curve segments.

[0097] In some specific embodiments, the total area difference determining unit may specifically include:

[0098] An updated acid exposure curve segment acquisition unit is used to delete the first small interval and the last small interval of each acid exposure curve segment to obtain an updated acid exposure curve segment;

[0099] The sub-area difference calculation unit is used to calculate the sub-area differences of the acid exposure sub-areas of all adjacent small intervals in all small intervals of the updated acid exposure curve segment.

[0100] In some specific embodiments, the acid clearance capacity analysis unit may specifically include:

[0101] A strong acid clearance ability determination unit, used for determining that the acid clearance ability is strong if the total area difference is greater than a first preset area difference threshold;

[0102] an acid clearance capacity general determination unit, configured to determine that the acid clearance capacity is general if the total area difference is less than the first preset area difference threshold and greater than the second preset area difference threshold; and the first preset area difference threshold is greater than the second preset area difference threshold;

[0103] The acid clearance ability weak determination unit is used to determine that the acid clearance ability is weak if the total area difference is less than the second preset area difference threshold.

[0104] Furthermore, the present application also discloses an electronic device, see Figure 8 As shown, the contents in the drawings should not be considered as any limitation on the scope of use of the present application.

[0105] Figure 8 The present invention is a schematic diagram of the structure of an electronic device 20 provided in an embodiment of the present application. The electronic device 20 may specifically include: at least one processor 21, at least one memory 22, a power supply 23, a communication interface 24, an input / output interface 25, and a communication bus 26. The memory 22 is used to store a computer program, which is loaded and executed by the processor 21 to implement the relevant steps in the gastroesophageal acid exposure degree analysis method disclosed in any of the aforementioned embodiments.

[0106] In this embodiment, the power supply 23 is used to provide working voltage for each hardware device on the electronic device 20; the communication interface 24 can create a data transmission channel between the electronic device 20 and the external device, and the communication protocol it follows is any communication protocol that can be applied to the technical solution of the present application, and is not specifically limited here; the input and output interface 25 is used to obtain external input data or output data to the outside world, and its specific interface type can be selected according to specific application needs and is not specifically limited here.

[0107] In addition, the memory 22, as a carrier for storing resources, can be a read-only memory, a random access memory, a disk or an optical disk, etc. The resources stored thereon include an operating system 221, a computer program 222, and data 223 including acid exposure curve segments, etc. The storage method can be temporary storage or permanent storage.

[0108] The operating system 221 is used to manage and control the hardware devices and computer programs 222 on the electronic device 20, so as to realize the operation and processing of the massive data 223 in the memory 22 by the processor 21, and it can be Windows Server, Netware, Unix, Linux, etc. In addition to including a computer program that can be used to complete the gastroesophageal acid exposure degree analysis method performed by the electronic device 20 disclosed in any of the aforementioned embodiments, the computer program 222 can further include a computer program that can be used to complete other specific tasks.

[0109] Furthermore, an embodiment of the present application also discloses a computer storage medium, in which computer executable instructions are stored. When the computer executable instructions are loaded and executed by a processor, the steps of the gastroesophageal acid exposure analysis method disclosed in any of the aforementioned embodiments are implemented.

[0110] In this specification, each embodiment is described in a progressive manner, and each embodiment focuses on the differences from other embodiments. The same or similar parts between the embodiments can be referred to each other. For the device disclosed in the embodiment, since it corresponds to the method disclosed in the embodiment, the description is relatively simple, and the relevant parts can be referred to the method part.

[0111] The steps of the method or algorithm described in conjunction with the embodiments disclosed herein may be implemented directly using hardware, a software module executed by a processor, or a combination of the two. The software module may be placed in a random access memory (RAM), a memory, a read-only memory (ROM), an electrically programmable ROM, an electrically erasable programmable ROM, a register, a hard disk, a removable disk, a CD-ROM, or any other form of storage medium known in the art.

[0112] Finally, it should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the presence of other identical elements in the process, method, article or device including the elements.

[0113] The above is a detailed introduction to a gastroesophageal acid exposure analysis method, device, equipment and storage medium provided by the present invention. Specific examples are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core idea. At the same time, for a person skilled in the art, according to the idea of ​​the present invention, there will be changes in the specific implementation method and application scope. In summary, the content of this specification should not be understood as limiting the present invention.

Claims

1. A method for analyzing gastroesophageal acid exposure, characterized in that: include: Obtain all acid exposure curve segments in the pH data curve corresponding to gastroesophageal pH monitoring; The acid exposure area is obtained according to the area formed between the acid exposure curve segment and the acid exposure pH threshold, and the total acid exposure area is obtained by summing the acid exposure areas corresponding to all acid exposure curve segments; The degree of acid exposure is analyzed based on the total acid exposure area; wherein the total acid exposure area is proportional to the degree of acid exposure.

2. The method for analyzing gastroesophageal acid exposure according to claim 1, characterized in that: The step of obtaining the acid exposure area according to the area formed between the acid exposure curve segment and the acid exposure pH threshold comprises: Dividing the acid exposure curve segment into a plurality of small intervals of equal duration according to a preset duration; Obtaining a pH difference according to a difference between the pH value corresponding to the small interval and the acid exposure pH threshold; According to the product of the pH difference corresponding to the small interval and the preset time length, the acid exposure sub-area corresponding to the small interval is obtained; The acid exposure area is obtained by summing the acid exposure sub-areas corresponding to all small intervals in the acid exposure curve segment and obtaining the area between the acid exposure curve segment and the acid exposure pH threshold.

3. The method for analyzing gastroesophageal acid exposure according to claim 1, characterized in that: The analyzing the degree of acid exposure according to the total acid exposure area comprises: If the total acid exposure area is greater than a first preset area threshold, it is determined to be acid exposure abnormality; If the total acid exposure area is less than the first preset area threshold and greater than the second preset area threshold, it is determined to be a suspected acid exposure abnormality; the first preset area threshold is greater than the second preset area threshold; If the total acid exposure area is smaller than the second preset area threshold, it is determined that the acid exposure is normal.

4. The method for analyzing gastroesophageal acid exposure according to any one of claims 1 to 3, characterized in that: Also includes: Dividing the acid exposure curve segment into a plurality of small intervals of equal duration according to a preset duration; Determine the acid exposure sub-area corresponding to each of the small areas, calculate the sub-area difference of the acid exposure sub-areas between all adjacent small areas, and obtain the total area difference by summing all the sub-area differences; The acid clearance capacity is analyzed based on the total area difference; the total area difference is proportional to the acid clearance capacity.

5. The method for analyzing gastroesophageal acid exposure according to claim 4, characterized in that: The calculating of the sub-area differences of the acid exposure sub-areas between all adjacent sub-areas and obtaining the total area difference by summing up all the sub-area differences comprises: Calculate the absolute value of the difference in acid exposure sub-areas between two adjacent small areas to obtain the sub-area difference between the adjacent small areas; According to the sub-area differences corresponding to all small intervals under the acid exposure curve segment, the area difference corresponding to the acid exposure curve segment is obtained; The total area difference is obtained by summing up the area differences corresponding to all the acid exposure curve segments.

6. The method for analyzing gastroesophageal acid exposure according to claim 4, characterized in that: The calculation of the sub-area differences of the acid exposure sub-areas between all adjacent sub-areas includes: Deleting the first small interval and the last small interval of each of the acid exposure curve segments to obtain an updated acid exposure curve segment; The sub-area differences of the acid exposure sub-areas between all adjacent small intervals in all the small intervals of the updated acid exposure curve segments are calculated.

7. The method for analyzing gastroesophageal acid exposure according to claim 4, characterized in that: The analyzing the acid clearance capacity according to the total area difference comprises: If the total area difference is greater than a first preset area difference threshold, it is determined that the acid clearance ability is strong; If the total area difference is less than the first preset area difference threshold and greater than the second preset area difference threshold, it is determined that the acid clearance capacity is average; the first preset area difference threshold is greater than the second preset area difference threshold; If the total area difference is less than the second preset area difference threshold, it is determined that the acid clearance ability is weak.

8. A gastroesophageal acid exposure analysis device, characterized in that: include: An acid exposure curve segment acquisition module, used to acquire all acid exposure curve segments in the pH data curve corresponding to gastroesophageal pH monitoring; an acid exposure total area determination module, configured to obtain the acid exposure area according to the area formed between the acid exposure curve segment and the acid exposure pH threshold, and obtain the acid exposure total area by summing the acid exposure areas corresponding to all acid exposure curve segments; The acid exposure degree analysis module is used to analyze the acid exposure degree according to the total acid exposure area; wherein the total acid exposure area is proportional to the acid exposure degree.

9. An electronic device, characterized in that: include: Memory, used to store computer programs; A processor, configured to execute the computer program to implement the method for analyzing gastroesophageal acid exposure as described in any one of claims 1 to 7.

10. A computer-readable storage medium, characterized in that: Used to store computer programs; wherein when the computer programs are executed by a processor, the method for analyzing gastroesophageal acid exposure as described in any one of claims 1 to 7 is implemented.

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