Hair care composition based on disulfide bond repair, cosmetic and application

Abstract

The invention belongs to the field of new daily chemical materials, and particularly relates to a hair care composition based on disulfide bond repair, which comprises silane modified collagen, cationized silk protein, small molecule keratin, polyhydroxypropyl arginine and derivatives thereof, and pyrrolidone ethanolamine salt. The composition is used for externally repairing hair cuticles, improving the hair strength and improving the fluffy texture of hair and internally repairing the interior of the hair through active disulfide bonds to inhibit moisture / nutrient substance loss and reduce the dry hair problem, and meanwhile, the scalp retention capacity of OCT can be improved through the formula, and the dandruff removing effect can be improved; in addition, the invention also provides a product containing the composition and application.

Description

Technical Field

[0001] The invention relates to the field of new daily chemical materials, and in particular to a hair care composition based on disulfide bond repair, cosmetics and uses. Background Art

[0002] The applicant's supplier, Chenghe Cosmetic Chemicals (Shanghai) Co., Ltd., has applied for a patent application, CN117898967A, the subject of which is a hair care composition based on disulfide bond repair, products acting on hair and uses;

[0003] It discloses a hair care composition based on disulfide bond repair, which is composed of hydrolyzed collagen PG-propylmethylsilanediol and hydrolyzed keratin with an average molecular weight of 400 Daltons; the weight ratio of hydrolyzed collagen PG-propylmethylsilanediol to hydrolyzed keratin with an average molecular weight of 400 Daltons is 0.5:0.15-0.75.

[0004] The mechanism is: it combines hydrolyzed collagen PG-propylmethylsilanediol and hydrolyzed keratin with an average molecular weight of 400 to act on the hair. On the outside, it forms a dense film layer to repair and protect the surface of the hair; on the inside, hydrolyzed collagen PG-propylmethylsilanediol can promote the hydrolyzed keratin with a molecular weight of 400 to enter the interior of the hair and repair the disulfide bonds.

[0005] The present application is still further improved and extended on the basis of the above scheme. In addition to further optimizing the disulfide bond repair function, it is also hoped to solve the scalp residence time of the traditional anti-dandruff agent OCT (octyl ketone ethanolamine salt) and improve the anti-dandruff effect.

[0006] The technical problem to be solved by the present invention is: how to develop a composition that can improve the disulfide bond repair level and improve the anti-dandruff effect. Summary of the invention

[0007] One of the purposes of the present invention is to provide a hair care composition based on disulfide bond repair, which can repair hair scales, improve hair strength, and enhance the fluffy texture of hair. It can also repair the inside of hair through active disulfide bonds to inhibit the loss of moisture / nutrients and reduce the problem of dry hair. At the same time, this formula can also improve the scalp retention ability of OCT and improve the anti-dandruff effect.

[0008] In addition, the present invention also provides cosmetics containing the composition and applications.

[0009] Unless otherwise specified, the molecular weights in the present invention are all in Daltons.

[0010] To achieve the above object, the present invention provides a disulfide bond repair-based hair care composition, comprising silane-modified collagen, cationized silk protein, small molecule keratin, polyhydroxypropyl arginine and its derivatives, and pyroximate ethanolamine salt;

[0011] The brand of the silane-modified collagen is Promois W-52SIGPD;

[0012] The brand of the cationic silk protein is Promois SILK-1000Q;

[0013] The brand of the small molecule keratin is Promois WK-PD.

[0014] The basic principle of the present invention is:

[0015] external:

[0016] 1. Repair the external hair scales through silane-modified collagen (Promois W-52SIGPD) and improve the strength of hair from the outside;

[0017] 2. Through cationic silk protein (Promois SILK-1000Q), the hair scales are smoothed in time, making the hair fluffy and smooth;

[0018] internal:

[0019] 1. Internal repair of damaged hair through the active disulfide bonds in small molecule keratin (Promois WK-PD);

[0020] 2. Use cationic silk protein (Promois SILK-1000Q) to repair the inside of the hair, inhibit the loss of moisture / nutrients, and reduce the problem of dry hair;

[0021] scalp:

[0022] The hydrogen bonding between Amitose R-PD and OCT increases the residence time of OCT on the scalp, enhancing its anti-dandruff effect while moisturizing the scalp for a long time.

[0023] At the same time, Amitose R-PD works together with the above-mentioned proteins to enhance the retention and penetration of active ingredients, thereby improving the internal and external repair effects of hair.

[0024] In the above-mentioned hair care composition based on disulfide bond repair, the weight ratio of the silane-modified collagen, the cationic silk protein, and the small-molecule keratin is 0.5:0.5-3.5:0.15-0.75.

[0025] In the above-mentioned hair care composition based on disulfide bond repair, the weight ratio of the polyhydroxypropyl arginine and its derivatives to pyroximate ethanolamine salt is 0.5-1:0.5-0.75.

[0026] In the above-mentioned disulfide bond repair-based hair care composition, the weight ratio of the silane-modified collagen, polyhydroxypropyl arginine and its derivatives is 0.5:0.5-1.

[0027] In the above-mentioned hair care composition based on disulfide bond repair, the structure of the polyhydroxypropyl arginine and its derivatives is shown in Formula I:

[0028]

[0029] In formula I, X is a hydrogen atom or -CH2CH(OH)CH2(OH); Y is a hydrogen atom, an alkali metal, ammonium, an organic ammonium or -CH2CH(OH)CH2(OH).

[0030] At the same time, the present invention also discloses the use of any of the above hair care compositions in preparing cosmetics.

[0031] In the above-mentioned use, the product is one of shampoo, conditioner, hair mask, wash-free hair conditioner, wash-free hair conditioner essence, and wash-free hair conditioner spray.

[0032] In addition, the present invention also discloses a product for hair, which contains 0.05-10 wt % of any one of the above hair care compositions and the balance of water.

[0033] In the above-mentioned product acting on hair, the product is a rinse-off product or a leave-on product;

[0034] Typical rinse-off products include: shampoo, conditioner, hair mask, etc.;

[0035] Typical leave-in products include: leave-in conditioner, leave-in conditioner essence, leave-in conditioner spray, etc.

[0036] The beneficial effects of the present invention are as follows:

[0037] The composition of the present invention repairs hair scales, improves hair strength, and enhances the fluffy texture of hair. It repairs the inside of hair through active disulfide bonds to inhibit the loss of moisture / nutrients and reduce the problem of dry hair. At the same time, this formula can also improve the scalp retention ability of OCT and improve the anti-dandruff effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0038] Figure 1 Internal penetration of a cross section of hair for marking the composition with a fluorescent dye;

[0039] Figure 2External penetration of the hair surface for marking the composition with the fluorescent dye. DETAILED DESCRIPTION

[0040] The technical solution of the present invention is further described in detail below, but does not constitute any limitation to the present invention.

[0041] Source of raw materials:

[0042] Silane-modified collagen: the trade name is Promois W-52SIGPD, the average molecular weight is 2200 Daltons, the solid content is 10wt%; the rest is solvent, wherein the solvent composition is: water, 1,2-pentanediol; supplier: Japan Seiwa Chemicals;

[0043] Cationic silk protein: the product name is Promois SILK-1000Q, the average molecular weight is 1200 Daltons, the solid content is 6wt%; the rest is solvent, wherein the solvent composition is: water, butylene glycol, methylparaben, propylparaben; supplier: Japan Seiwa Chemical;

[0044] Small molecule keratin: the trade name is Promois WK-PD, the average molecular weight is 400 Daltons, the solid content is 25wt%; the rest is solvent, wherein the solvent composition is: water, 1,2-pentanediol; supplier: Japan Seiwa Chemicals;

[0045] Dihydroxypropyl arginine hydrochloride: the trade name is Amitose R-PD (AR for short), solid content is 30wt%; the rest is solvent, wherein the solvent composition is: water, 1,2-pentanediol; supplier: Japan Seiwa Chemicals.

[0046] Examples 1-5 and Comparative Examples 1 to 5

[0047] A composition, the formula of which is provided in Table 1, is prepared by adding various raw materials into water and stirring evenly.

[0048] Table 1 Formula table Unit: g

[0049]

[0050]

[0051] Performance Testing

[0052] Test item 1: protein fluorescence staining experiment;

[0053] Testing instrument: fluorescence microscope;

[0054] Test range: exposure time / hair section: 100ms, hair side: 200ms;

[0055] Measurement environment: humidity 43±2% temperature 20℃;

[0056] Determination method:

[0057] 1. The test hair was permed 5 times;

[0058] 2. Test the cross-sectional area of ​​the hairs, divide them into 15 groups, 20 hairs in each group, so that the average cross-sectional area of ​​each group is equal;

[0059] 3. The above composition was treated with FL (Fluorescein) fluorescent labeling at 40° C. for 30 minutes;

[0060] 4. After washing and drying, observe the cross section and side of the hair using a fluorescence microscope.

[0061] The test sample is the sample of Example 1, Figure 1 The internal penetration of the hair cross section is shown. Figure 2 External penetration of the hair surface is shown.

[0062] Test item 2: Hair friction coefficient test;

[0063] Testing instrument: friction testing machine;

[0064] Test amplitude: 2cm;

[0065] Speed: 0.5mm / sec.;

[0066] Measurement environment: humidity 43±2% temperature 20℃;

[0067] Determination method:

[0068] 1. Test hair for decolorization;

[0069] 2. Test the cross-sectional area of ​​hair, divide it into 15 groups, each group has 20 hairs, make the average cross-sectional area of ​​each group equal, place 20 hairs in parallel on 8 slides, measure the friction coefficient, and divide the samples into 2 groups with the same average friction coefficient;

[0070] 3. Treat with each group of conditioners (Examples 1 to 5, Comparative Examples 1 to 5) for 10 minutes, wash with running water (40°C, 1 min) and dry; the blank group is treated with clean water;

[0071] 4. Conduct friction coefficient test. The test results can be seen in Table 2.

[0072] Test item 3: Hair strength test;

[0073] Testing instrument: High-sensitivity hair tensile testing machine;

[0074] Test range: 5cm;

[0075] Speed: 1.0mm / sec.;

[0076] Measurement environment: humidity 58±2% temperature 25℃;

[0077] Determination method:

[0078] 1. Test hair for decolorization;

[0079] 2. Test the cross-sectional area of ​​the hairs, divide them into 15 groups, 20 hairs in each group, so that the average cross-sectional area of ​​each group is equal;

[0080] 3. Treat with each group of conditioners (Examples 1 to 5, Comparative Examples 1 to 5) for 10 minutes, wash with running water (40°C, 1 min) and dry; the blank group is treated with clean water;

[0081] 4. Carry out strength test. The test results can be seen in Table 2.

[0082] Test Item 4: Scalp moisturizing, scalp oil and odor improvement, and dandruff control experiments;

[0083] The sensory evaluation test method is as follows:

[0084] 1. Establishment of the evaluation team

[0085] Evaluators: 35 persons, randomly divided into 7 groups, the test samples are shampoos as shown in Table 7, the shampoos are added with the compositions shown in Examples 2 to 5 and Comparative Examples 2, 3 and 5, and the dosage is 5%; the evaluators need to be trained on the evaluation indicators and evaluation principles before the test.

[0086] 2. Implementation of sensory evaluation

[0087] Before the evaluation, use a towel to dry the water on the scalp and hair after washing, enter the evaluation room together, and wait quietly for 3 minutes before starting the test. The test site is the head, and the sensory characteristics of the three stages during the use process are evaluated. See Table 3 for details.

[0088] Table 2 Hair test results

[0089] Strength (kgf / hair) <![CDATA[Average coefficient of friction (*10 -1 )]]> Example 1 191 1.13 Example 2 197 1.06 Example 3 213 1.02 Example 4 189 1.15 Example 5 205 1.05 Comparative Example 1 178 1.26 Comparative Example 2 175 1.13 Comparative Example 3 170 1.31 Comparative Example 4 162 1.35 Comparative Example 5 172 1.28

[0090] Table 3 Scalp test results

[0091]

[0092]

[0093] Result analysis:

[0094] Depend on Figure 1 , Figure 2As is known, the composition of the present invention can effectively penetrate into the damaged hair, be adsorbed onto the surface of the damaged hair, and supplement and repair the hair structure.

[0095] It can be seen from Examples 1 to 5 in Table 2 that the hair strength is maintained above 189 kgf / hair, and the average friction coefficient is maintained at 1.15*10 -1 the following;

[0096] It can be seen from Example 4 and Comparative Example 2 in Table 2 that the average friction coefficient of Comparative Example 2 is similar to that of Example 4; at the same time, it can be seen from Comparative Example 5 in Table 2 that its average friction coefficient is worse than that of Example 4; the above three cases can be combined to prove that: 1. The importance of cationized silk protein in reducing the friction coefficient is greater than that of small molecule keratin; 2. The function of cationized silk protein in reducing the friction coefficient needs to be achieved in conjunction with AR; appropriately increasing the cationized silk protein can further reduce the friction coefficient, as shown in Example 3;

[0097] It can be seen from Example 4, Comparative Example 1, Comparative Example 2 and Comparative Example 3 in Table 2 that small molecule keratin, cationic silk protein and AR are all important for hair strength.

[0098] It can be seen from Table 3 that AR is more important to improve the effect of OCT. In the absence of AR, the health of the scalp will decrease. The combination of AR and OCT can effectively nourish the scalp.

[0099] At the same time, the present invention also provides a rinse-off product and a leave-on product formulation, which can use the composition of any of the above embodiments and comparative examples.

[0100] The specific formula of the rinse-off type (shampoo) product can be found in Table 7, and the formula of the leave-on type (non-rinse hair spray) product can be found in Table 8;

[0101] Table 7 Recipe

[0102]

[0103]

[0104] Table 8 Recipe

[0105]

[0106]

[0107] The above embodiments are preferred implementation modes of the present invention, but the implementation modes of the present invention are not limited to the above embodiments. Any other changes, modifications, substitutions, combinations, and simplifications that do not deviate from the spirit and principles of the present invention should be equivalent replacement methods and are included in the protection scope of the present invention.

Claims

1. A hair care composition based on disulfide bond repair, characterized in that: Including silane-modified collagen, cationic silk protein, small molecule keratin, polyhydroxypropyl arginine and its derivatives, and pyroxetine ethanolamine salt; The brand of the silane-modified collagen is Promois W-52SIGPD; The brand of the cationic silk protein is Promois SILK-1000Q; The brand of the small molecule keratin is Promois WK-PD.

2. The disulfide bond repairing hair care composition according to claim 1, characterized in that: The weight ratio of the silane-modified collagen, the cationic silk protein and the small-molecule keratin is 0.5:0.5-3.5:0.15-0.

75.

3. The disulfide bond repair-based hair care composition according to claim 1, characterized in that: The weight ratio of the polyhydroxypropyl arginine and its derivatives to the pyroximate ethanolamine salt is 0.5-1:0.5-0.

75.

4. The disulfide bond repairing hair care composition according to claim 1, characterized in that: The weight ratio of the silane-modified collagen, polyhydroxypropyl arginine and its derivatives is 0.5:0.5-1.

5. The disulfide bond repairing hair care composition according to claim 1, characterized in that: The structure of polyhydroxypropyl arginine and its derivatives is shown in Formula I: In formula I, X is a hydrogen atom or -CH2CH(OH)CH2(OH); Y is a hydrogen atom, an alkali metal, ammonium, an organic ammonium or -CH2CH(OH)CH2(OH).

6. Use of the hair care composition according to any one of claims 1 to 5 in preparing cosmetics.

7. The use according to claim 6, characterized in that The product is one of shampoo, conditioner, hair mask, no-wash hair conditioner, no-wash hair conditioner essence, and no-wash hair conditioner spray.

8. A cosmetic, characterized in that: The method comprises 0.05 to 10 wt % of the hair care composition according to any one of claims 1 to 5 and the balance of water.

9. The cosmetic according to claim 7, characterized in that: The cosmetic is a wash-off product or a leave-on product.

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