Traditional Chinese medicine composition for early prevention of laying hen salpingitis and preparation method and application thereof

By using traditional Chinese herbal compositions prepared by using traditional Chinese herbal compositions such as yellow vine, savory balm, parsley and sage, the problems of the complexity of preventing and treating fallopian tube inflammation in the prior art and the long time to use the medicine, achieving rapid and effective prevention and treatment effects.

CN119837926APending Publication Date: 2025-04-18WUHAN SUNHY BIOLOGICAL
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Patent Information

Application Number
CN202510011311.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-03
Publication Date
2025-04-18

AI Technical Summary

Technical Problem

The prior art has problems such as complex formulation, long medication time, and unclear mechanism of action in preventing and treating fallopian tube inflammation in laying hens, and long-term use may lead to reduced effect of functional additives.

Method used

Traditional Chinese herbal compositions such as yellow vine, balm, parsley and sage are prepared through steps such as alcohol extraction and water decoction, which are used to prevent and treat fallopian tube inflammation in the laying hen in the early stage.

Benefits of technology

This traditional Chinese medicine composition has the effects of clearing heat and detoxifying, promoting dampness, etc., which can improve the immunity and anti-stress ability of laying hens, promote the development of fallopian tubes, prevent fallopian tube inflammation, and the medication time is short and the effect is significant.

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Abstract

The invention relates to a traditional Chinese medicine composition for early prevention of laying hen salpingitis as well as a preparation method and application thereof. The traditional Chinese medicine composition comprises the following raw material components in parts by weight: 20-30 parts of herba fibraureae recisae, 10-15 parts of melissa officinalis, 5-10 parts of parsley and 5-10 parts of salvia officinalis. The traditional Chinese medicine composition provided by the invention is obtained by reasonable compatibility according to the traditional Chinese medicine syndrome differentiation treatment principle, coordinates and gains the drug effect together, has the effects of clearing away heat and toxic materials, relaxing the bowels and removing dampness, and can improve the immunity and anti-stress ability of laying hens, promote the development of fallopian tubes of the laying hens and prevent fallopian tube inflammation in the peak laying period and the later laying period.
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Description

Technical Field

[0001] The invention relates to the technical field of Chinese herbal medicines for livestock and poultry, and in particular to a Chinese medicine composition for early prevention of oviduct inflammation in laying hens, and a preparation method and application thereof. Background Art

[0002] Fallopian tube inflammation is a common disease in laying hen farming, which has serious harm to the production efficiency and health of laying hens. Fallopian tube inflammation in laying hens can cause depression in sick birds, reduced feed intake and egg production, abnormal egg quality and deformed egg shape. In severe cases, it may cause swelling, congestion, ulceration and other lesions in the fallopian tubes, which in turn cause fallopian tube blockage and increase the risk of pathogenic microorganisms spreading in the chicken house. Frequent fallopian tube inflammation has caused huge economic losses to laying hen farming and affected the healthy development of the laying hen farming industry.

[0003] There are many treatments for oviduct inflammation in laying hens, but starting treatment after symptoms appear will delay egg production efficiency and egg quality. There are also some feed formulas or additives on the market for preventing oviduct inflammation, but they are basically fed throughout the entire breeding cycle. With the increasing popularity of enzyme preparations and feed additives with various functions, long-term feeding of feed or additives for preventing oviduct inflammation may conflict with enzymes or additives with other functions, resulting in a decrease in the effectiveness of various functional additives. Summary of the invention

[0004] In view of the existing technical problems, the present invention provides a traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens, as well as a preparation method and application thereof. The composition has the characteristics of reasonable formulation, fast treatment course and flexible medication time. It can prevent oviduct inflammation in the early stage and also has a certain therapeutic effect on laying hens that have already suffered from oviduct inflammation.

[0005] In order to achieve the above object, the present invention adopts the following technical solutions: A traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens comprises the following raw material components in weight ratio: 20-30 parts of yellow vine, 10-15 parts of lemon balm, 5-10 parts of parsley and 5-10 parts of sage.

[0006] Optionally, the raw material components are included in the following weight ratio: 10-20 parts of yellow vine, 12-14 parts of lemon balm, 6-8 parts of parsley, and 7-8 parts of sage.

[0007] Optionally, the raw material components are included in the following weight ratio: 5 parts of yellow vine, 13 parts of lemon balm, 12 parts of parsley, and 8 parts of sage.

[0008] Based on the above technical solution, the present invention also provides a method for preparing a Chinese medicine composition for early prevention of oviduct inflammation in laying hens, comprising the following steps: 1) Weighing the drug raw materials according to the weight ratio, and drying, crushing, sieving and setting aside the raw materials; 2) extracting the sieved Phellodendron chinense with alcohol to obtain a Phellodendron chinense extract; 3) mixing the Phellodendron chinense extract with other reserved components, decocting with water, and concentrating to obtain a traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens.

[0009] Optionally, step 1) of drying, crushing and sieving the raw materials separately specifically includes: drying the raw materials at 60-70° C. for 6-8 hours, and then crushing them into 18-40 meshes.

[0010] Optionally, step 2) extracting the sieved Phellodendron chinense with alcohol to obtain the Phellodendron chinense extract specifically comprises: soaking the sieved Phellodendron chinense raw material in 40-60% ethanol as a solvent for 3-4 hours and then drying at 60-70°C, wherein the solid-liquid ratio of the Phellodendron chinense raw material to the solvent is 1:(5-7).

[0011] Optionally, the decoction in water in step 3) is concentrated to obtain a traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens, which specifically includes: decocting with water at a ratio of 1: (6-8) over medium heat for 3-5 hours, and concentrating the obtained medicinal solution to 1 / 4-1 / 3 of the volume.

[0012] On the basis of the above technical solution, the present invention also provides the use of the above traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens in the preparation of a medicine for preventing oviduct inflammation in laying hens.

[0013] On the basis of the above technical solution, the present invention also provides a laying hen feed, comprising the above-mentioned traditional Chinese medicine composition for early prevention of laying hen oviduct inflammation.

[0014] Optionally, in the laying hen feed, the mass proportion of the traditional Chinese medicine composition for early prevention of laying hen oviduct inflammation is 0.1% to 0.3%.

[0015] Compared with the prior art, the Chinese medicine composition for early prevention of oviduct inflammation in laying hens provided by the present invention and its preparation method and application have the following advantages: (1) The present invention selects Chinese herbal medicines such as yellow vine, lemon balm, parsley and sage, and uses the principle of traditional Chinese medicine differentiation and treatment to reasonably combine them, which work together to enhance the efficacy of the medicine, have the effects of clearing away heat and detoxifying, relieving constipation and relieving dampness, can improve the immunity and anti-stress ability of laying hens, promote the development of the oviduct of laying hens, and prevent oviduct inflammation during the peak and late egg-laying period.

[0016] (2) The Chinese medicine composition provided by the present invention has a clear therapeutic effect on the early prevention of oviduct inflammation in laying hens. The medication time is short, and a significant preventive effect can be achieved in 2 to 3 weeks. The medication time is flexible and the medication can be used in the early stage of egg production. It is highly versatile and can be used in combination with any laying hen feed.

[0017] (3) The present invention is made of pure Chinese herbal medicine, the raw materials used are widely available, the cost is low, there is no drug residue, no toxic side effects, the preparation process is simple, the application range is wide, and it has a high market value. DETAILED DESCRIPTION

[0018] The principles and features of the present invention are described below in conjunction with specific embodiments. The examples given are only used to explain the present invention and are not intended to limit the scope of the present invention. Unless otherwise defined, all technical and scientific terms used herein belong to the meanings commonly understood by those skilled in the art of the present invention. The terms used in the specification of the present invention herein are only for the purpose of describing specific embodiments and are not intended to limit the present invention.

[0019] It should be noted that, in the absence of conflict, the features in the embodiments of the present invention can be combined with each other. The terms "comprise", "include", "contain" and "have" are non-restrictive, that is, other steps and other components that do not affect the results can be added.

[0020] According to the basic theory of Chinese veterinary medicine, laying hens are susceptible to external evils such as toxins or overwork in laying eggs, which lead to the five internal evils, such as damp-heat caking and difficult to clear, blood stasis and lumps, which lead to poor circulation of qi and blood, dysfunction of internal organs, and inability to remove rot and regenerate new organs in the face of injuries, resulting in dampness stagnation, blood stasis, qi stagnation, cold stagnation, and insufficient positive energy, which aggravates their susceptibility to external evils such as "dampness", thus suffering from salpingitis. The treatment principle is to reduce swelling and dampness, clear away heat and detoxify, soothe the liver and strengthen the spleen, and nourish yin and tonify the kidney.

[0021] Many Chinese herbal medicines have the effects of clearing away heat and detoxification, promoting blood circulation and removing blood stasis, and antibacterial and anti-inflammatory effects, and have certain potential for relieving inflammation in laying hens' oviducts. However, existing Chinese herbal medicine prevention and treatment programs have problems such as complex formulas, long medication time, and unclear mechanisms of action.

[0022] To solve the above problems, an embodiment of the present invention provides a traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens, comprising the following raw material components in weight ratio: 20-30 parts of yellow vine, 10-15 parts of lemon balm, 5-10 parts of parsley, and 5-10 parts of sage.

[0023] The pharmacology of the above Chinese herbal medicine raw materials is as follows: Huangteng: bitter and cold in nature. It enters the heart and liver meridians. It has the effects of attacking stagnation, clearing dampness and heat, purging fire, cooling blood, removing blood stasis, and detoxifying. It is used for internal heat and toxicity, constipation, diarrhea, sore throat, red and swollen eyes, carbuncle and sore.

[0024] Melissa officinalis: pungent and cool in nature. It enters the heart and liver meridians. It has the effects of calming the mind, soothing the liver, relieving depression, and relieving pain. It is used to treat symptoms such as restlessness, insomnia, forgetfulness, palpitations, depression, irritability, anxiety, abdominal pain, toothache, etc. It is widely used to treat mental and central nervous system diseases, cardiovascular diseases, etc., and is also used as an anti-anxiety drug, sleep aid, and detoxification agent.

[0025] Parsley: A non-traditional Chinese medicinal material, it is considered in some Western herbal medicines to have antioxidant, anti-inflammatory, diuretic and detumescent, sedative and tranquilizing effects, and the ability to maintain cardiovascular health.

[0026] Sage: bitter, pungent, neutral in nature. Clears away heat and dampness, promotes blood circulation and regulates menstruation, detoxifies and reduces swelling. Used for jaundice, red and white diarrhea, damp-heat diarrhea, irregular menstruation, dysmenorrhea, sores, furunculosis, and traumatic injuries.

[0027] In the Chinese medicine composition of the present invention, the Radix Phellodendri is used as the main drug, which has the effects of reducing swelling and toxicity, clearing dampness and heat, and the Herba Lysimachiae is used as the assistant drug, which has the effects of clearing heat and dampness, promoting blood circulation and detoxifying, reducing inflammation and relieving pain, and enhancing the effects of the main drug in reducing swelling and removing dampness. Therefore, the present invention is reasonably compatible according to the principle of syndrome differentiation and treatment of traditional Chinese veterinary medicine, gives full play to the effects of each drug, and the combination of the drugs synergistically increases the efficacy, has the effects of clearing heat and detoxifying, relieving urination and dampness, can enhance immunity and relieve symptoms, effectively improve the immunity and anti-stress ability of laying hens, promote the development of the oviduct of laying hens, and prevent the inflammation of the oviduct during the peak and late egg-laying period.

[0028] Preferably, the Chinese medicinal composition for early prevention of oviduct inflammation in laying hens comprises the following raw material components in weight ratio: 10-20 parts of yellow vine, 12-14 parts of lemon balm, 6-8 parts of parsley, and 7-8 parts of sage.

[0029] Furthermore, the Chinese medicinal composition for early prevention of oviduct inflammation in laying hens includes raw material components in the following weight ratio: 5 parts of yellow vine, 13 parts of lemon balm, 12 parts of parsley, and 8 parts of sage.

[0030] Another embodiment of the present invention provides a method for preparing a Chinese medicine composition for early prevention of oviduct inflammation in laying hens, comprising the following steps: 1) Weighing the drug raw materials according to the weight ratio, and drying, crushing, sieving and setting aside the raw materials; 2) extracting the sieved Phellodendron chinense with alcohol to obtain the Phellodendron chinense extract; 3) mixing the Phellodendron chinense extract with other reserved components, decocting with water, and concentrating to obtain the traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens.

[0031] Among them, step 1) drying, crushing and sieving the raw materials respectively, specifically comprising: drying the raw materials at 60-70° C. for 6-8 hours, and then crushing them into 18-40 meshes.

[0032] The invention solves the problem that the traditional Chinese medicine powder has high crude fiber content and the effective components are difficult to dissolve by crushing the Chinese medicine to destroy the plant cell wall to the maximum extent.

[0033] Step 2) extracting the sieved Phellodendron chinense with alcohol to obtain the Phellodendron chinense extract, specifically comprising: soaking the sieved Phellodendron chinense raw material in 40-60% ethanol as a solvent for 3-4 hours and then drying at 60-70° C., wherein the solid-liquid ratio of the Phellodendron chinense raw material to the solvent is 1: (5-7).

[0034] In the present invention, the rhizoma coptidis can remove heat and toxins in the body, reduce inflammatory reactions, play anti-inflammatory and antibacterial roles in preventing and treating inflammation of the oviduct of laying hens, and improve the body resistance of laying hens.

[0035] Among them, step 3) is decocted with water, and after concentration, a traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens is obtained, which specifically includes: decocting with water at a ratio of 1: (6-8) on medium heat for 3-5 hours, and concentrating the obtained medicinal liquid to 1 / 4-1 / 3 of the volume.

[0036] It is understandable that the compatibility principle of Chinese veterinary medicine is "increasing efficacy and reducing toxicity", so the pharmacological effects of different compatibility drugs are also different. The Chinese medicine composition provided by the present invention is scientifically formulated without any toxic side effects, has a significant effect on the early prevention of oviduct inflammation in laying hens, and has a much higher efficacy than single-prescription drugs. In addition, the present invention is made of pure Chinese herbal medicines, the raw Chinese herbal medicines used are widely available, the cost is low, there is no drug residue, no toxic side effects; the preparation process is simple, and the scope of application is wide, and it has a high market value.

[0037] On the basis of the above technical solution, the third embodiment of the present invention further provides the use of the above traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens in the preparation of a medicine for preventing oviduct inflammation in laying hens.

[0038] Preferably, the medicine comprises the above-mentioned early prevention of oviduct inflammation in laying hens and auxiliary materials. Meanwhile, according to actual needs, different dosage forms can be prepared, including but not limited to powders, premixes, tablets, powders, granules, etc.

[0039] On the basis of the above technical solution, the present invention also provides a laying hen feed, comprising the above-mentioned traditional Chinese medicine composition for early prevention of laying hen oviduct inflammation.

[0040] Preferably, the mass proportion of the Chinese medicine composition for early prevention of oviduct inflammation in laying hens in laying hen feed is 0.1% to 0.3%. Specifically, the Chinese medicine composition prepared above is added to ordinary laying hen feed at a ratio of 0.1% to 0.3%, and mixed evenly step by step to obtain laying hen feed for early prevention of oviduct inflammation in laying hens.

[0041] Specifically, the medication time is: when laying hens are 18 to 25 weeks old, add 0.1% to 0.2% of the Chinese medicine composition to the feed, and feed it continuously for 2 to 3 weeks, which can achieve the effect of preventing inflammation of the fallopian tubes during the peak and late egg-laying period. In addition, when the medication is used during the period of 25 to 54 weeks of age, 0.2% to 0.3% of the Chinese medicine composition needs to be added to the feed, and fed continuously for 2 to 3 weeks, which can prevent inflammation of the fallopian tubes and also has a certain therapeutic effect on individuals who have already suffered from inflammation of the fallopian tubes.

[0042] It is understandable that the common laying hen feed can be any commercially available conventional laying hen feed, which will not be listed here one by one.

[0043] Therefore, the Chinese medicine composition for early prevention of oviduct inflammation in laying hens provided in the present application has a short medication time, and only takes 2 to 3 weeks to achieve a significant preventive effect; the medication time is flexible, and it can be used in the early stage of egg laying, and can also be adjusted according to the medication time of other functional additives in the feed; it is highly versatile, and does not clearly specify the feed formula, and can be used with any feed.

[0044] The present invention will be further described below in conjunction with specific examples. It should be understood that these examples are only used to illustrate the present invention and are not intended to limit the scope of the present invention. The experimental methods for which specific conditions are not specified in the following examples are usually based on the conditions recommended by the manufacturer. Unless otherwise stated, percentages and parts are calculated by mass. Example 1 This embodiment provides a method for preparing a Chinese medicine composition for early prevention of oviduct inflammation in laying hens, the steps are as follows: 1) Dry the Psoralea corylifolia, lemon balm, parsley and sage at 65°C for 8 hours, and crush them into 18 mesh for later use; 2) Take 30 parts of the crushed Psoralea corylifolia and soak them in 45% ethanol as a solvent for 3 hours with a solid-liquid ratio of 1:5, and then dry them at 70°C to obtain a Psoralea corylifolia extract for later use; 3) Evenly mix the Psoralea corylifolia extract, 12 parts of lemon balm, 8 parts of parsley and 8 parts of sage, and boil them with water at a ratio of 1:8 over medium heat for 5 hours, and concentrate the resulting medicinal solution to 1 / 4 of its volume to obtain a traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens.

[0045] The Chinese medicinal composition for early prevention of oviduct inflammation in laying hens prepared in Example 1 was added to laying hen feed at a ratio of 0.1%, and mixed evenly step by step to obtain laying hen feed A. The Chinese medicinal composition for early prevention of oviduct inflammation in laying hens prepared in Example 1 was added to ordinary laying hen feed at a ratio of 0.25%, and mixed evenly step by step to obtain laying hen feed B. Among them, ordinary laying hen feed is a conventional laying hen feed available on the market.

[0046] Example 2 This embodiment provides a method for preparing a Chinese medicine composition for early prevention of oviduct inflammation in laying hens, the steps are as follows: 1) Dry the Psoralea corylifolia, lemon balm, parsley and sage at 60°C for 8 hours, and crush them into 40 meshes for later use; 2) Take 25 parts of the crushed Psoralea corylifolia, soak them in 40% ethanol as a solvent for 4 hours, with a solid-liquid ratio of 1:7, and then dry them at 70°C to obtain a Psoralea corylifolia extract for later use; 3) Evenly mix the Psoralea corylifolia extract, 15 parts of lemon balm, 10 parts of parsley and 10 parts of sage, boil them with water at a ratio of 1:6 over medium heat for 3 hours, and concentrate the resulting medicinal solution to 1 / 4 of its volume to obtain a traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens.

[0047] Example 3 This embodiment provides a method for preparing a Chinese medicine composition for early prevention of oviduct inflammation in laying hens, the steps are as follows: 1) Dry the Psoralea corylifolia, lemon balm, parsley and sage at 70°C for 6 hours, and crush them into 30 meshes for later use; 2) Take 20 parts of the crushed Psoralea corylifolia, soak them in 60% ethanol as a solvent for 4 hours, with a solid-liquid ratio of 1:6, and then dry them at 60°C to obtain a Psoralea corylifolia extract for later use; 3) Evenly mix the Psoralea corylifolia extract, 10 parts of lemon balm, 5 parts of parsley and 5 parts of sage, boil them with water at a ratio of 1:6 over medium heat for 5 hours, and concentrate the resulting medicinal solution to 1 / 3 of its volume, thereby obtaining a traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens.

[0048] Test Example 1 Laying hen feed A and laying hen feed B were evaluated through laying hen breeding experiments. The specific method is as follows: 1080 laying hens of the same age were used as test animals and divided into a control group, an early prevention group and a peak prevention group. There were 6 replicates in each group and 60 hens in each replicate. The experiment was started after the egg production rate was adjusted to be consistent. The control group was fed with normal laying hen feed throughout the whole period, the early prevention group was fed with laying hen feed A for 2 consecutive weeks at 21-22 weeks, and the peak prevention group was fed with laying hen feed B for 2 consecutive weeks at 40-41 weeks. In the late egg-laying period (60 weeks of age), the egg production rate, dirty egg rate and blood egg rate of each group were statistically analyzed for 1 week. The results are shown in Table 1. * Indicates significant difference, P<0.05.

[0049] Table 1 Statistics of egg production of 60-week-old laying hens

[0050] As can be seen from Table 1, the egg laying rate of the early prevention group and the peak prevention group was significantly higher than that of the control group, and the dirty egg rate and blood egg rate were significantly lower than those of the control group, which indicates that the Chinese medicine composition for early prevention of oviduct inflammation in laying hens provided by the present invention has the effect of reducing the incidence of oviduct inflammation in the early stage and during the peak egg-laying period.

[0051] Test Example 2 Laying hen feed A and laying hen feed B were evaluated by modeling oviduct inflammation in laying hens. The specific method is as follows: 360 laying hens of the same age were used as experimental animals and divided into a control group, a modeling group, an early prevention group and a peak prevention group, with 5 replicates in each group and 18 hens in each replicate. The experiment was started after the egg production rate was adjusted to be consistent. Among them, the control group and the modeling group were fed with normal laying hen feed throughout the whole period, the early prevention group was fed with laying hen feed A for 2 consecutive weeks at 21-22 weeks, and the peak prevention group was fed with laying hen feed B for 2 consecutive weeks at 40-41 weeks. At 45 weeks of age, individuals in the modeling group, early prevention group and peak prevention group were modeled for oviduct inflammation with phenol slurry, and the control group was treated with 0.75% normal saline, and the egg production situation was counted 1 week before and 1 week after modeling. The results are shown in Table 2. In the table * Indicates significant difference, P<0.05 Table 2 Statistics of egg laying in laying hens before and after 45 weeks of age

[0052] As can be seen from Table 2, there was no significant change in the egg production rate of the control group after modeling, but the egg production rate of the modeling group, early prevention group and peak prevention group decreased significantly one week after modeling, and the dirty egg rate and blood egg rate increased significantly, but the egg production rate of the early prevention group and peak prevention group decreased to a lower degree, and the dirty egg rate and blood egg rate increased to a lower degree. The results show that the Chinese medicine composition for early prevention of oviduct inflammation in laying hens has the effect of preventing the occurrence of oviduct inflammation and relieving oviduct inflammation in the early stage and during the peak egg-laying period.

[0053] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A Chinese medicine composition for early prevention of oviduct inflammation in laying hens, characterized in that: The invention comprises the following raw material components in weight ratio: 20-30 parts of yellow rattan, 10-15 parts of lemon balm, 5-10 parts of parsley and 5-10 parts of sage.

2. The Chinese medicinal composition for early prevention of oviduct inflammation in laying hens according to claim 1, characterized in that: The invention comprises the following raw material components in weight ratio: 10-20 parts of yellow rattan, 12-14 parts of lemon balm, 6-8 parts of parsley and 7-8 parts of sage.

3. The Chinese medicine composition for early prevention of oviduct inflammation in laying hens according to claim 2, characterized in that: The invention comprises raw material components in the following weight ratio: 5 parts of yellow vine, 13 parts of lemon balm, 12 parts of parsley and 8 parts of sage.

4. A method for preparing the Chinese medicine composition for early prevention of oviduct inflammation in laying hens according to any one of claims 1 to 3, characterized in that: The following steps are involved: 1) Weighing the drug raw materials according to the weight ratio, and drying, crushing, sieving and setting aside the raw materials; 2) extracting the sieved Phellodendron chinense with alcohol to obtain a Phellodendron chinense extract; 3) mixing the Phellodendron chinense extract with other reserved components, decocting with water, and concentrating to obtain a traditional Chinese medicine composition for early prevention of oviduct inflammation in laying hens.

5. The method for preparing the Chinese medicine composition for early prevention of oviduct inflammation in laying hens according to claim 4, characterized in that: Step 1) drying, crushing and sieving the raw materials separately specifically comprises: drying the raw materials at 60-70° C. for 6-8 hours, and then crushing them into 18-40 meshes.

6. The method for preparing the Chinese medicine composition for early prevention of oviduct inflammation in laying hens according to claim 4, characterized in that: Step 2) extracting the sieved Phellodendron chinense with alcohol to obtain the Phellodendron chinense extract specifically comprises: soaking the sieved Phellodendron chinense raw material in 40-60% ethanol as a solvent for 3-4 hours and then drying at 60-70°C, wherein the solid-liquid ratio of the Phellodendron chinense raw material to the solvent is 1:(5-7).

7. The method for preparing the Chinese medicinal composition for early prevention of oviduct inflammation in laying hens according to claim 4, characterized in that: Step 3) decocting with water and concentrating to obtain a Chinese medicine composition for early prevention of oviduct inflammation in laying hens specifically comprises: decocting with water at a ratio of 1: (6-8) over medium heat for 3-5 hours, and concentrating the obtained medicinal solution to 1 / 4-1 / 3 of the volume.

8. Use of the Chinese medicinal composition for early prevention of oviduct inflammation in laying hens according to any one of claims 1 to 3 in the preparation of a drug for preventing oviduct inflammation in laying hens.

9. A laying hen feed, characterized in that: A Chinese medicinal composition for early prevention of oviduct inflammation in laying hens comprising the Chinese medicinal composition according to any one of claims 1 to 3.

10. The laying hen feed according to claim 9, characterized in that: In the laying hen feed, the mass proportion of the traditional Chinese medicine composition for early prevention of laying hen oviduct inflammation is 0.1% to 0.3%.

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