Special film blowing unit for powder liquid film

Abstract

The invention relates to the field of powder-liquid film blowing machines, particularly discloses a special film blowing unit for powder-liquid films, and solves the technical problems that no special equipment exists, the production cost is high, the compatibility with multiple varieties is poor, and the film quality is unstable in the current powder-liquid film blowing process. The special film blowing unit for the powder liquid film comprises a feeding unit, a blowing unit and a blowing unit, the extrusion unit comprises a plurality of extruders, and the extruders are connected with the feed hoppers in a one-to-one correspondence manner; the film blowing unit is provided with a die head connected to the discharge end of the extruder; the coiling unit is provided with a film collecting roller located at the film outlet end of the die head; and the cooling unit comprises an air cooling assembly and a water cooling assembly which are arranged between the film collecting roller and the die head, is special equipment for blowing the powder liquid film, and is low in production cost, good in compatibility with multiple varieties and stable in film material quality.

Description

Technical Field

[0001] The invention relates to the technical field of powder-liquid film blowing machines, and in particular to a special film blowing machine unit for powder-liquid films. Background Art

[0002] Powder-liquid dual chamber bag film, i.e., matched powder-liquid dual chamber bag, as an innovative form of pharmaceutical packaging, has brought significant convenience and efficiency to clinical medication. It not only simplifies the drug preparation process, allowing medical staff to quickly and accurately administer drugs in emergency situations, but also greatly reduces the possibility of human errors, thereby improving the safety and accuracy of medication. This packaging form is particularly suitable for drugs that require solid powder and liquid to be mixed immediately before use, such as certain antibiotics or special therapeutic agents.

[0003] Membrane material is one of the core technologies of powder-liquid dual-chamber bags. It needs to have high strength, good flexibility and chemical stability in the face of multiple drug ingredients. In addition, the membrane material must ensure absolute sealing between the two independent chambers to prevent cross-contamination, while ensuring that it can be safely broken under specified conditions (such as temperature and pressure) to achieve rapid mixing of the two substances. However, at present, there is still a lack of production equipment specifically designed for powder-liquid dual-chamber bags on the domestic market. Although the existing general-purpose film blowing units can be used to produce such film materials, firstly, since non-dedicated equipment cannot achieve the optimal process parameters, the manufacturing cost per unit product is relatively high; secondly, different drug varieties have different requirements for film materials, and existing equipment is difficult to meet the high requirements of multi-variety production, which affects the quality consistency of drugs and increases the risk of clinical application. Summary of the invention

[0004] The purpose of the present invention is to provide a special powder-liquid film blowing machine unit to solve the technical problems in the current powder-liquid film blowing process, such as lack of special equipment, high production cost, poor compatibility with multiple varieties, and unstable film material quality.

[0005] The present invention provides a special film blowing machine unit for powder-liquid film, comprising: a feeding unit, provided with a plurality of feeding hoppers; an extrusion unit, comprising a plurality of extruders, wherein the extruders and the feeding hoppers are connected one by one; a film blowing unit, provided with a die head connected to the discharge end of the extruder; a winding unit, provided with a film collecting roller located at the film discharge end of the die head; and a cooling unit, comprising an air cooling component and a water cooling component arranged between the film collecting roller and the die head.

[0006] According to one embodiment of the present invention, the die head is a multi-layer stacked die head, which is formed by stacking a plurality of disc-shaped sheets, and each layer of the disc-shaped sheets is provided with two feed ports.

[0007] According to one embodiment of the present invention, each layer of the disc-shaped sheet includes a feed channel, an upper flow channel and a lower flow channel, the feed channel is connected to the feed port, the feed channel extends into the disc-shaped sheet and is divided into an upper flow channel and a lower flow channel, and the upper flow channel and the lower flow channel converge into a die discharge channel.

[0008] According to one embodiment of the present invention, a heat insulation layer is provided between the layers of disc-shaped sheets.

[0009] According to one embodiment of the present invention, the die head is made of 38CrMoAIA material.

[0010] According to one embodiment of the present invention, the die gap of the die head is 2.5-3.0 mm.

[0011] According to one embodiment of the present invention, the extruder is provided with a planetary screw having a length-to-diameter ratio of 30:1 to 36:1.

[0012] According to one embodiment of the present invention, the extruder is connected to a melt pump via a melt distributor, and the melt pump is connected to a die head.

[0013] According to one embodiment of the present invention, an online thickness gauge is further provided between the cooling unit and the coiling unit.

[0014] The technical solution of the present invention has at least the following advantages and beneficial effects: The present invention provides a powder liquid film blowing unit, which aims to solve the problems of lack of equipment, high production cost, poor variety compatibility and unstable film quality in the current powder liquid film blowing process. The present invention is composed of a feeding unit, an extrusion unit, a film blowing unit, a winding unit and a cooling unit, wherein: (1) The feeding unit of the present invention is different from the popular multi-component batch feeding and continuous screw feeding on the market; the present invention adopts the feeding method controlled by the extruder screw speed vector, that is, the instantaneous feeding amount of raw materials depends on the speed of the screw and the extrusion processing temperature. The prerequisite is that the three melt pumps extract equal values ​​of melt from the melt distributor according to the pre-set value. The melt distributor controls the screw speed when the instantaneous demand of the three melt pumps is met, thereby driving the instantaneous feeding amount of raw materials.

[0015] (2) The extruder system of the present invention is different from the popular single-screw extruder on the market. It adopts an ultra-long aspect ratio of 30:1 to 36:1, so that a variety of polymers with melting points that differ by more than 50°C can be well plasticized. No crystal points or black spots are generated, especially for making infusion bags, reducing the generation of waste products (crystal points and black spots on the film surface), saving quality risks in the upstream granulation process, and reducing costs.

[0016] (3) The feed channel of the multi-layer superimposed die head of the present invention extends into the feed pipe and is divided into an upper flow channel and a lower flow channel, that is, two layers of film can be extruded, thereby increasing the film production efficiency.

[0017] (4) The heat-insulating layer is added between the disc-shaped sheets of the present invention, and the temperature of each layer of die head can be controlled individually. The temperature difference between adjacent layers can be as high as 80°C. According to different production requirements, the die heads of each layer can be removed, added or rearranged, which is easy to increase or decrease and saves costs.

[0018] (5) The entire die head of the present invention is made of 38CrMoAIA material, which has good thermal stability, ensures the strength of the film, saves raw materials, improves plasticizing properties, and improves product quality. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments are briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work.

[0020] Figure 1 This is a right side view of the structure of a powder-liquid film blowing machine unit provided in Example 1 of the present invention.

[0021] Figure 2 This is a structural front view of a special powder-liquid film blowing machine unit provided in Example 1 of the present invention.

[0022] Figure 3 This is a top view of the structure of a powder-liquid film blowing machine unit provided in Example 1 of the present invention.

[0023] Figure 4 This is a schematic diagram of the die head structure of a powder-liquid film blowing machine unit provided in Example 1 of the present invention.

[0024] Figure 5 for Figure 4 Enlarged view of point A in the middle; Figure 6 This is a schematic structural diagram of a feed hopper and an extruder of a powder-liquid film blowing machine unit provided in Example 2 of the present invention.

[0025] Reference numerals: 110. Feed hopper; 210, extruder; 211, planetary screw; 212, melt distributor; 213, melt pump; 214, Screen changer; 310, die head; 311, inner layer; 312, sub-inner layer; 313, core layer; 314, sub-outer layer; 315, outer layer; 316, feed channel; 317, upper flow channel; 318, lower flow channel; 319, discharge channel; 400, coiling unit; 510, traction roller group; 520, driving motor; 600, Online thickness gauge; 700, membrane road. DETAILED DESCRIPTION

[0026] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Generally, the components of the embodiments of the present invention described and shown in the drawings here can be arranged and designed in various different configurations.

[0027] Example 1 Embodiment 1 of the present invention provides a special film blowing machine unit for powder-liquid film to improve product quality and reduce costs.

[0028] See also Figure 1 , Figure 2 as well as Figure 3 , the powder liquid film blowing machine unit provided in the embodiment of the present invention comprises: a feeding unit, provided with a plurality of feeding hoppers 110 for feeding materials; An extrusion unit, comprising a plurality of extruders 210, wherein the extruders 210 are connected to the feed hoppers 110 in a one-to-one correspondence; A film blowing unit, provided with a die head 310 connected to the discharge end of the extruder 210; The winding unit 400 is provided with a film-receiving roller located at the film-exiting end of the die head 310. In this embodiment, the film-receiving roller is driven by a film-receiving driving motor to rotate. The cooling unit includes an air cooling component and a water cooling component disposed between the film collection roller and the die head 310. The extrusion unit is disposed on the support frame. The air cooling component and the water cooling component cool the film. In this embodiment, the air cooling component has a reference publication number of CN118478508A, which is an automatic film blowing machine air ring. In this embodiment, the water cooling component includes a primary water ring and a secondary water ring located below the primary water ring, the primary water ring includes a ring wall, an annular water storage chamber is formed around the ring wall, a water inlet is opened on the outer wall of the annular water storage chamber, a detachable water storage chamber cover is installed above the annular water storage chamber, an overflow port is formed between the water storage chamber cover and the ring wall, an annular vacuum chamber is arranged below the annular water storage chamber, and the annular vacuum chamber is connected to the inside of the ring wall, the secondary water ring includes an inner ring wall and an outer ring wall, a water accumulation chamber is formed between the inner ring wall and the outer ring wall, and a wiper ring is arranged at the top of the inner ring wall.

[0029] In this embodiment, a circular ring-shaped spoiler is provided in the annular water storage chamber.

[0030] In this embodiment, a plurality of partition plates are arranged in the annular vacuum chamber, and the plurality of partition plates divide the annular vacuum chamber into a plurality of independent vacuum areas, and each of the vacuum areas is respectively connected to the inside of the annular wall.

[0031] In this embodiment, a vacuum ring groove is provided on the inner wall of the ring wall, and a plurality of water holes are opened on the vacuum ring groove. Each of the vacuum areas is connected to the inside of the ring wall through the water holes, and each of the vacuum areas is provided with a suction port connected to the outside.

[0032] In this embodiment, an atomizer is provided at the bottom of the annular wall, and the atomizer is connected to an external water source.

[0033] In this embodiment, an annular groove is provided on the top of the water storage chamber cover.

[0034] In this embodiment, a water ring bracket plate is provided at the bottom of each of the primary water ring and the secondary water ring, and the two water ring bracket plates are connected by a water ring screw.

[0035] In this embodiment, the annular vacuum chamber includes an outer wall of the vacuum chamber, a top plate fixedly connected to the outer wall of the vacuum chamber, a bottom plate detachably connected to the outer wall of the vacuum chamber, and an annular wall fixedly connected to the top plate and the bottom plate respectively, and the outer wall of the annular water storage chamber is detachably connected to the outer wall of the vacuum chamber.

[0036] The annular water storage chamber in the primary water ring in this embodiment can temporarily store clean water under external pressure to release the pressure. The water storage chamber cover can prevent foreign matter from falling into the water ring to avoid contaminating the product. The annular vacuum chamber can extract the water from the inside of the ring wall after cooling the product, and the extracted water can be recycled after treatment. The scraper ring in the secondary water ring can remove an appropriate amount of cooling water from the surface of the bubble to prevent the weight of the water curtain attached to the surface of the bubble from being too heavy and affecting the downward movement of the bubble, avoid wrinkling and deformation of the bubble, and improve the quality of the bubble. The cooling water scraped off by the scraper ring is stored in the water accumulation chamber, discharged from the water outlet of the water accumulation chamber, and recycled after treatment. It is suitable for medical infusion membrane blowing.

[0037] In the present embodiment, a rotary traction unit is further provided between the cooling unit and the winding unit 400, and the rotary traction unit includes a traction roller group 510 provided below the die head 310, and the traction roller group 510 includes two traction rollers arranged at intervals and connected by a synchronous belt. In the present embodiment, the two traction rollers are non-contact clamped and are two mirror stainless steel rollers of the same diameter. In the present embodiment, any traction roller is driven to rotate by a driving motor 520. Since the two traction rollers are connected by a synchronous belt, the two traction rollers move synchronously, and the film surface is wrapped around the large wrap angle of the two rollers, which can trap the air in the film and is not squeezed by the rollers. In the present embodiment, the rotary traction unit drives the traction rollers to rotate by the driving motor 520, so that the film bubble rotates slowly and uniformly at ±180° relative to the die head 310, so that the trace thickness points of the film are evenly distributed on the film roll, thereby obtaining a smoother film roll, greatly improving the appearance quality of the film roll.

[0038] See also Figure 4 In this embodiment, the die head 310 is a multi-layer stacking die head 310, which is composed of a plurality of disc-shaped pieces stacked together. Each layer of the disc-shaped pieces is provided with two feed ports, and each disc-shaped piece is spaced apart in the vertical direction, and has a compact structure. Compared with the conical stacking die head 310 in the prior art, the actual height is only 60% of the conical stacking die head 310, thereby increasing the effective height of the tower.

[0039] In this embodiment, a heat insulation layer is provided between each disc-shaped piece. In this embodiment, the heat insulation layer is a ceramic fiber heat insulation layer. The temperature of each layer of the die head can be controlled individually, and the temperature difference between adjacent layers can be as high as 80°C. According to different production requirements, the die heads of each layer can be removed, added or rearranged, which is easy to increase or decrease and saves costs.

[0040] In this embodiment, the feed channel 316 of each disc-shaped piece is arranged perpendicular to the overall central axis of the die head 310, and the material is fed from the side. There are few turning points in the flow channel in the die head, no dead points, and no sticking phenomenon during frequent shutdown and startup.

[0041] In this embodiment, the die head 310 is made of 38CrMoAIA material to ensure good thermal stability; the die gap of the die head 310 is set to 2.5-3.0 mm, which is suitable for the production of high-quality films.

[0042] In this embodiment, a bubble control system is provided at the film outlet of the die head 310, and the bubble control system is an optical fiber controller. When the bubble is smaller than the grating line, the pneumatic solenoid valve opens to inflate the bubble, and when the bubble is larger than the grating line, the pneumatic solenoid valve is disconnected and the air supply stops. The system operates reciprocatingly.

[0043] See also Figure 5 In this embodiment, each of the disc-shaped pieces includes a feed channel, an upper flow channel 317 and a lower flow channel 318. The feed channel is connected to the feed port. The feed channel extends into the disc-shaped piece and is divided into an upper flow channel 317 and a lower flow channel 318. The upper flow channel 317 and the lower flow channel 318 converge to the die discharge channel 319. The material introduced from one feed port passes through the feed channel 316 and is separated and moved to the upper flow channel 317 and the lower flow channel 318 arranged around the disc-shaped piece. That is, the material is separated by the upper flow channel 317 and the lower flow channel 318 to form two layers of membrane, and the two layers of membrane are discharged through the discharge channel 319, which enhances the strength of the membrane material and saves raw materials at the same time.

[0044] In this embodiment, the disc-shaped piece is provided with multiple layers in sequence from top to bottom along the vertical direction, including: an inner layer 311, a middle layer and an outer layer 315; wherein the middle layer is provided with multiple layers, and the middle layer includes a sub-inner layer 312, a core layer 313 and a sub-outer layer 314 arranged in sequence from top to bottom along the vertical direction, that is, in this embodiment, 5 screws are used to realize an 11-layer interface membrane structure, and the characteristics under a microscope show a 22-layer membrane structure, which increases the strength of the membrane material and improves the production line yield.

[0045] In this embodiment, the die gap of the die head 310 is 2.5-3.0 mm.

[0046] In this embodiment, the die diameter of the die head 310 is 140-160 mm.

[0047] In this embodiment, an online thickness gauge 600 is also provided between the cooling unit and the winding unit 400 to monitor and adjust the film thickness in real time to ensure product quality. The online thickness gauge 600 uses a capacitive inductive transverse scanning thickness gauge and adopts non-contact capacitance to measure the thickness of the film. The distance between the sensor and the film surface is measured by induction technology, and the thickness value of the insulator is measured more accurately by using a capacitive sensor. First, the distance between the measuring probe and the roller surface is calibrated, and then the distance from the thick film surface to the measuring probe is measured. The difference between the two is the actual thickness of the film. Because it is a real-time online measurement, the thickness data of the film can be tracked in real time and transmitted to the central control system to produce a real-time curve profile of the film. It is convenient for users to record and analyze process quality. The central control system is mainly composed of industrial control computers and communication modules, heating output modules, solid-state heating output and other components. It generates real-time curves and profiles and records them by receiving real-time thickness data from the thickness measuring system. Then it is compared with the set value and the size of the heating power is automatically output to the actuator. To adjust the thickness profile in real time to meet the user's requirements.

[0048] Example 2 Embodiment 2 of the present invention provides a special film blowing machine unit for powder-liquid film to improve product quality and reduce costs.

[0049] See also Figure 6 The powder liquid film blowing machine unit provided in the embodiment of the present invention is different from the embodiment 1 only in that, please refer to Figure 5 In this embodiment, the extruder 210 is provided with a planetary screw 211 with a length-to-diameter ratio of 30:1 to 36:1 to ensure good plasticization of a variety of polymers. The raw material feed amount is adjusted according to the screw speed and the processing temperature. The melt pump 213 extracts an equal amount of melt from the melt distributor 212 to ensure precise control.

[0050] In this embodiment, the extruder 210 is connected to the melt pump 213 through the melt distributor 212, and the melt pump 213 is connected to the die head 310. The melt pump 213 extracts equal value of melt from the melt distributor 212 according to the pre-set value. The melt distributor 212 controls the speed of the screw when the instantaneous demand of the three melt pumps 213 is met, thereby driving the instantaneous discharge amount of the raw material. The melt distributor 212 and the melt pump 213 are controlled by the PLC system. In this embodiment, a screen changer 214 is provided at the end of the screw rod of the extruder 210, and the screen changer 214 is connected to the melt pump 213 through the melt distributor 212.

[0051] The following is a detailed description of the use of the powder liquid film special film blowing machine unit of the present invention: See also Figure 1The film circuit 700 is shown in the figure. When in use, the material is passed into the extruder 210 through the feed hopper 110, and the extruder 210 feeds the die head 310. The material is discharged by controlling the speed of the screw of the discharge machine in a vector-controlled manner. The three melt pumps 213 extract equal amounts of melt from the melt distributor 212 according to the preset value. The melt distributor 212 controls the speed of the screw when the instantaneous demand of the three melt pumps 213 is met, thereby driving the instantaneous discharge amount of the raw material. The die head 310 performs the demoulding operation. By rotating the traction unit, the drive motor 520 drives any traction roller to rotate. Then the two traction rollers move synchronously, and the film surface is wrapped around the two rollers with a large wrap angle, which traps the air in the film without being squeezed by the rollers, so that the film bubble rotates slowly and evenly at ±180° relative to the die head 310, so that the slight thickness points of the film are evenly distributed on the film roll, thereby obtaining a smoother film roll and greatly improving the appearance quality of the film roll. After being cooled by the cooling unit, the film is rolled up by the winding unit 400.

[0052] The embodiments of the present invention have at least the following advantages: The present invention provides a powder liquid film blowing unit, which aims to solve the problems of lack of equipment, high production cost, poor variety compatibility and unstable film quality in the current powder liquid film blowing process. The present invention is composed of a feeding unit, an extrusion unit, a film blowing unit, a winding unit and a cooling unit, wherein: (1) The feeding unit of the present invention is different from the popular multi-component batch feeding and continuous screw feeding on the market; the present invention adopts the feeding method controlled by the extruder screw speed vector, that is, the instantaneous feeding amount of raw materials depends on the speed of the screw and the extrusion processing temperature. The prerequisite is that the three melt pumps extract equal values ​​of melt from the melt distributor according to the pre-set value. The melt distributor controls the screw speed when the instantaneous demand of the three melt pumps is met, thereby driving the instantaneous feeding amount of raw materials.

[0053] (2) The extruder system of the present invention is different from the popular single-screw extruder on the market. It adopts an ultra-long aspect ratio of 30:1 to 36:1, so that a variety of polymers with melting points that differ by more than 50°C can be well plasticized. No crystal points or black spots are generated, especially for making infusion bags, reducing the generation of waste products (crystal points and black spots on the film surface), saving quality risks in the upstream granulation process, and reducing costs.

[0054] (3) The feed channel of the multi-layer superimposed die head of the present invention extends into the feed pipe and is divided into an upper flow channel and a lower flow channel, that is, two layers of film can be extruded, thereby increasing the film production efficiency.

[0055] (4) The heat-insulating layer is added between the disc-shaped sheets of the present invention, and the temperature of each layer of die head can be controlled individually. The temperature difference between adjacent layers can be as high as 80°C. According to different production requirements, the die heads of each layer can be removed, added or rearranged, which is easy to increase or decrease and saves costs.

[0056] (5) The entire die head of the present invention is made of 38CrMoAIA material, which has good thermal stability, ensures the strength of the film, saves raw materials, improves plasticizing properties, and improves product quality.

[0057] (6) Compared with the conical stacking die head, under the same conditions, the die head of the present invention has a compact structure and its actual height is only 60% of that of the conical stacking die head, thereby increasing the effective height of the tower.

[0058] (7) The die head is a flat superposition type, which adopts side feeding. There are few turning points in the flow channel of the die head, no dead points, and no sticking phenomenon during frequent shutdown and startup.

[0059] (8) The winding unit uses a sector gear motion pair to make the entire traction system (including the herringbone plate) rotate slowly and evenly at ±180° relative to the die head and the film bubble, so that the slight thickness points of the film are evenly distributed on the film roll, thereby obtaining a smoother film roll and greatly improving the appearance quality of the film roll.

[0060] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A powder liquid film blowing machine unit, characterized in that: include: A feeding unit, provided with a plurality of feeding hoppers; An extrusion unit, comprising a plurality of extruders, wherein the extruders and the feed hoppers are connected one by one; a film blowing unit, provided with a die head connected to the discharge end of the extruder; A winding unit is provided with a film-collecting roller located at the film-discharging end of the die head; The cooling unit comprises an air cooling component and a water cooling component which are arranged between the film collecting roller and the die head.

2. The powder-liquid film blowing machine unit according to claim 1 is characterized in that: The die head is a multi-layer superimposed die head, which is formed by superimposing a plurality of disc-shaped sheets, and each layer of the disc-shaped sheets is provided with two feed ports.

3. The powder-liquid film blowing machine unit according to claim 1 is characterized in that: Each layer of the disc-shaped sheet comprises a feed channel, an upper flow channel and a lower flow channel. The feed channel is connected to the feed port. The feed channel extends into the disc-shaped sheet and is divided into an upper flow channel and a lower flow channel. The upper flow channel and the lower flow channel converge into a die discharge channel.

4. The powder-liquid film blowing machine unit according to claim 2 or 3, characterized in that: A heat insulation layer is arranged between the layers of disc-shaped sheets.

5. The powder-liquid film blowing machine unit according to claim 1 is characterized in that: The die head is made of 38CrMoAIA material.

6. The powder-liquid film blowing machine unit according to claim 1, characterized in that: The die gap of the die head is 2.5-3.0 mm.

7. The powder-liquid film blowing machine unit according to claim 1, characterized in that: The extruder is provided with a planetary screw with a length-to-diameter ratio of 30:1 to 36:

1.

8. The powder-liquid film blowing machine unit according to claim 1, characterized in that: The extruder is connected to a melt pump via a melt distributor, and the melt pump is connected to a die head.

9. The powder-liquid film blowing machine unit according to claim 1, characterized in that: An online thickness gauge is also provided between the cooling unit and the coiling unit.

Images