Low-temperature anti-freezing efficient disinfectant
By formulating a low-temperature antifreeze-efficient disinfectant containing disinfectants, antifreeze and other additives, the problem of disinfectant inactivation in low-temperature environments is solved, and the disinfection effect that is still effective in environments below -35°C is achieved.
Patent Information
- Application Number
- CN202510223499.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-27
- Publication Date
- 2025-04-25
AI Technical Summary
In low temperature environments, the disinfectant loses its activity and cannot be used normally, which affects the disinfection effect.
Ensure that the disinfectant is still effective in a low-temperature antifreeze environment by formulating a high-efficiency disinfectant including disinfectants, antifreeze, water hardness regulators, anticorrosion agents, additives, stabilizers, thickeners and benzalkonium chloride.
The disinfectant still has a disinfection effect in a low temperature environment of -35°C, avoiding the problem of disinfectant inactivation caused by low temperature, and improving the disinfection effect and convenience of use through thickeners and stabilizers.
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of disinfectants, and in particular to a low-temperature antifreeze and high-efficiency disinfectant. Background Art
[0002] Disinfectants, as daily-use medicines, can be used in various environments, such as utensils, pens, equipment and means of transportation, all of which can be used for disinfection. Currently, disinfectants are used at room temperature in daily life, because the activity of disinfectants is more active at room temperature and the disinfection effect is better. However, when used in actual scenarios, such as disinfecting pens in winter, the temperature is very low in winter, and the temperature is lower in the north. In this case, when disinfecting the pens, the disinfectant will lose its activity directly because the temperature is too low, resulting in the disinfectant being unable to be used normally and failing to play a disinfection role, affecting its use. Summary of the invention
[0003] In order to make up for the above deficiencies, the present invention provides a low-temperature antifreeze high-efficiency disinfectant that overcomes the above technical problems or at least partially solves the above problems.
[0004] The present invention is achieved in that:
[0005] The invention provides a low-temperature antifreeze high-efficiency disinfectant, which is characterized by comprising 10-40 parts of a disinfectant, 20-30 parts of an antifreeze agent, 40-50 parts of a water hardness regulator, 10-30 parts of an anticorrosive agent, 5-15 parts of an auxiliary agent, 30-40 parts of a stabilizer, 10-25 parts of a thickener and 30-50 parts of benzalkonium chloride.
[0006] In a preferred embodiment, the disinfectant is selected from one or more of sodium dichloroisocyanurate, sodium hypochlorite, hydrogen peroxide and peracetic acid.
[0007] In a preferred embodiment, the antifreeze agent is selected from one or more of acetic acid, propylene glycol, sodium chloride, calcium chloride and sodium formate to prevent freezing and allow the liquid to be used normally.
[0008] In a preferred embodiment, the water hardness regulator is selected from one or more of ion exchange resin, trisodium phosphate, and chelating agent.
[0009] In a preferred embodiment, the corrosion inhibitor is selected from one or more of chromate, phosphate, cyclohexyl carbonate and dicyclohexyl ammonium nitrite.
[0010] In a preferred embodiment, the auxiliary agent includes a pH regulator and water. When preparing, the water is room temperature water, and the temperature is set at 20°C-25°C.
[0011] In a preferred embodiment, the stabilizer is selected from one or more of propylene glycol, glycerol, disodium ethylenediaminetetraacetate and borax.
[0012] In a preferred embodiment, the thickener is selected from one or more of hydroxyethyl cellulose and xanthan gum, and the viscosity of the xanthan gum will decrease when subjected to external force.
[0013] In a preferred embodiment, the disinfectant may also be glutaraldehyde, which reacts with amino, carboxyl, sulfhydryl and other groups in microbial protein to coagulate and denature the protein.
[0014] In a preferred embodiment, the concentration of glutaraldehyde is set to 2%-10%.
[0015] The invention provides a low-temperature antifreeze efficient disinfectant, which has the following beneficial effects:
[0016] By setting the disinfectant and antifreeze, the disinfectant can be used in a low-temperature environment and still has a disinfection effect in an environment with a temperature of -35°C. The device is also provided with a water hardness regulator in the matching table. The water hardness regulator can adjust the water hardness in the product to avoid freezing so that the product can be used normally. The product is also provided with a thickener and a stabilizer to increase the disinfection effect of the product and improve the use effect. DETAILED DESCRIPTION
[0017] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in combination with the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0018] Embodiment 1
[0019] The invention provides a technical solution: a low-temperature antifreeze high-efficiency disinfectant, comprising 10 parts of a disinfectant, 20 parts of an antifreeze agent, 40 parts of a water hardness regulator, 10 parts of an anticorrosive agent, 5 parts of an auxiliary agent, 30 parts of a stabilizer, 10 parts of a thickener and 30 parts of benzalkonium chloride.
[0020] In a preferred embodiment, the disinfectant is sodium dichloroisocyanurate, which decomposes hypochlorous acid in water to exert a disinfecting effect. It has the characteristics of a broad bactericidal spectrum and strong bactericidal ability. Under low temperature conditions, it can still maintain good disinfection performance and is a relatively ideal low-temperature disinfectant.
[0021] In a preferred embodiment, the antifreeze agent is acetic acid, which is used to prevent ice formation and allow the liquid to be used normally. The freezing point of ethanol is -114.1°C. It also lowers the freezing point by forming hydrogen bonds with water molecules. Ethanol is a relatively safe antifreeze agent. Propylene glycol is a diol, which has two isomers, 1,2-propylene glycol and 1,3-propylene glycol. 1,2-propylene glycol is commonly used. Its freezing point is relatively low, about -60°C. Propylene glycol can effectively lower the freezing point of the solution when mixed with water.
[0022] In a preferred embodiment, the water hardness regulator is an ion exchange resin. The ion exchange resin is a polymer material with exchangeable ions, which is divided into cation exchange resin and anion exchange resin. The cation exchange resin contains acidic groups (such as sulfonic acid group -SO3H) and can exchange with calcium and magnesium ions in water.
[0023] The corrosion inhibitor is selected from chromate, which is an effective corrosion inhibitor, such as sodium chromate (Na2CrO4) and potassium chromate (K2CrO4). This film is very dense and can prevent corrosive media such as oxygen and water from further contacting the metal, thereby playing an anti-corrosion role; phosphate corrosion inhibitors such as sodium phosphate (Na3PO4), sodium tripolyphosphate (Na5P3O 10 ) etc., which can form an insoluble phosphate protective film.
[0024] The auxiliary agent includes a pH regulator and water. When preparing, water is selected to be room temperature water, and its temperature is set at 20°C-25°C. In a low temperature environment, the activity of the disinfectant may be affected by changes in pH value. The pH regulator includes phosphate, and the phosphate buffer can maintain the pH value of the disinfectant solution within a relatively stable range, thereby ensuring the effectiveness of the disinfectant.
[0025] The stabilizer is propylene glycol. In low-temperature disinfectants, polyols can be used as effective stabilizers. Taking propylene glycol as an example, it not only has certain antifreeze properties, but also can stabilize the active ingredients in the disinfectant. Under low-temperature conditions, some ingredients in the disinfectant (such as peroxides or chlorine-containing ingredients) may become unstable due to the decrease in temperature. Propylene glycol can maintain its stability by interacting with these ingredients. It can reduce the activity of the ingredients, reduce the decomposition or reaction rate at low temperatures, and also prevent the components from condensing or precipitating due to temperature changes.
[0026] The thickener is hydroxyethyl cellulose, which is a commonly used thickener. When added in an appropriate amount, it can increase the consistency of the disinfectant, but will not make it completely impossible to spray. When a small amount of HEC is added, the fluidity of the disinfectant will be slightly worse, but it can still be sprayed through equipment such as a sprayer.
[0027] The disinfectant can also be glutaraldehyde, which reacts with amino, carboxyl, sulfhydryl and other groups in microbial proteins to coagulate and denature the proteins. The concentration of the glutaraldehyde is set to 2%-10%. Glutaraldehyde is a highly effective disinfectant that has a good killing effect on bacteria, viruses, spores, etc. Its disinfection mechanism is to coagulate and denature the proteins by reacting with amino, carboxyl, sulfhydryl and other groups in microbial proteins. In the sterilization of pens, a 2% glutaraldehyde solution is generally used. It can be used to immerse and disinfect metal utensils (such as feeders, waterers, etc.) in pens, and can also be used to disinfect other surfaces by spraying.
[0028] Embodiment 2
[0029] A low-temperature antifreeze high-efficiency disinfectant comprises 40 parts of disinfectant, 30 parts of antifreeze, 50 parts of water hardness regulator, 30 parts of corrosion inhibitor, 15 parts of auxiliary agent, 40 parts of stabilizer, 25 parts of thickener and 50 parts of benzalkonium chloride.
[0030] In a preferred embodiment, the disinfectant is hydrogen peroxide. The disinfection principle of hydrogen peroxide is that it has strong oxidizing properties and can produce hydroxyl free radicals with bactericidal ability. In a low temperature environment, the reaction rate of hydrogen peroxide will slow down, but it still has a disinfecting effect. It can be used in a low temperature environment of about -30°C.
[0031] In a preferred embodiment, the antifreeze agent is propylene glycol, which is a diol with two isomers, 1,2-propylene glycol and 1,3-propylene glycol, of which 1,2-propylene glycol is commonly used. It has a low freezing point of about -60°C. When mixed with water, propylene glycol can effectively lower the freezing point of the solution.
[0032] In a preferred embodiment, the water hardness regulator is trisodium phosphate, which will ionize into phosphate ions (PO4 3- Phosphate ions react with calcium and magnesium ions to form insoluble calcium phosphate (Ca3(PO4)2) and magnesium phosphate (Mg3(PO4)2) precipitates. These precipitates can be removed from the water, thereby reducing the hardness of the water.
[0033] The corrosion inhibitor is selected from phosphate, such as sodium phosphate (Na3PO4), sodium tripolyphosphate (Na5P3O 10 ) etc., which can form an insoluble phosphate protective film.
[0034] The auxiliary agent includes a pH regulator and water. When preparing, water is selected to be room temperature water, and its temperature is set at 20°C-25°C. In a low temperature environment, the activity of the disinfectant may be affected by changes in pH value. The pH regulator includes phosphate, and the phosphate buffer can maintain the pH value of the disinfectant solution within a relatively stable range, thereby ensuring the effectiveness of the disinfectant.
[0035] The stabilizer is glycerol, which has multiple hydroxyl groups in its molecular structure and can form hydrogen bonds with other components in the disinfectant. This hydrogen bonding can fix the position of the components to a certain extent and maintain the uniformity of the solution.
[0036] The thickener is xanthan gum, and the viscosity of the xanthan gum is reduced when it is subjected to external force. The xanthan gum thickener can make the disinfectant have good rheological properties at low temperatures. At a suitable concentration, it can make the disinfectant present the characteristics of a pseudoplastic fluid, that is, it is relatively viscous when stationary, but when subjected to a certain external force (such as the pressure of a sprayer), its viscosity is reduced, so that it can be sprayed out smoothly.
[0037] The disinfectant can also be glutaraldehyde, which reacts with amino, carboxyl, sulfhydryl and other groups in microbial proteins to coagulate and denature the proteins. The concentration of the glutaraldehyde is set to 2%-10%. Glutaraldehyde is a highly effective disinfectant that has a good killing effect on bacteria, viruses, spores, etc. Its disinfection mechanism is to coagulate and denature the proteins by reacting with amino, carboxyl, sulfhydryl and other groups in microbial proteins. In the sterilization of pens, a 2% glutaraldehyde solution is generally used. It can be used to immerse and disinfect metal utensils (such as feeders, waterers, etc.) in pens, and can also be used to disinfect other surfaces by spraying.
[0038] Embodiment 3
[0039] The invention provides a technical solution: a low-temperature antifreeze high-efficiency disinfectant, comprising 20 parts of disinfectant, 25 parts of antifreeze, 45 parts of water hardness regulator, 20 parts of corrosion inhibitor, 11 parts of auxiliary agent, 35 parts of stabilizer, 18 parts of thickener and 40 parts of benzalkonium chloride.
[0040] In a preferred embodiment, the disinfectant is peracetic acid, which is a highly effective disinfectant with a stronger bactericidal ability than hydrogen peroxide. It destroys the cell wall, cell membrane, and intracellular nucleic acid, protein and other biological macromolecules of microorganisms through oxidation to achieve disinfection.
[0041] In a preferred embodiment, the antifreeze agent is sodium chloride, which is a common salt antifreeze agent. When sodium chloride is dissolved in water, it will ionize sodium ions (Na + ) and chloride ions (Cl -), these ions will interact with water molecules to form hydrated ions. The formation of this hydrated ion prevents the water molecules from forming the normal lattice structure of ice crystals. According to the freezing point depression formula, the freezing point of the solution will decrease as the molar fraction of the solute (sodium chloride) increases. For example, when the concentration of sodium chloride solution reaches 23.3% (mass fraction), its freezing point can be reduced to -21.13℃.
[0042] In a preferred embodiment, the water hardness regulator is a chelating agent, which is a chemical substance that can form a stable ring structure (chelate) with metal ions. Common chelating agents include ethylenediaminetetraacetic acid (EDTA) and its sodium salt (such as EDTA-disodium). EDTA molecules contain multiple coordination atoms (nitrogen atoms and carboxyl oxygen atoms), which can form multiple coordination bonds with calcium and magnesium ions, wrapping calcium and magnesium ions inside its molecular structure, so that these ions lose the ability to react with other substances to form scale.
[0043] The anti-corrosion agent is cyclohexyl carbonate, which is also a vapor phase corrosion inhibitor. Its vapor can form a protective film on the metal surface to achieve a corrosion inhibition effect.
[0044] The auxiliary agent includes a pH regulator and water. When preparing, water is selected to be room temperature water, and its temperature is set at 20°C-25°C. In a low temperature environment, the activity of the disinfectant may be affected by changes in pH value. The pH regulator includes phosphate, and the phosphate buffer can maintain the pH value of the disinfectant solution within a relatively stable range, thereby ensuring the effectiveness of the disinfectant.
[0045] The stabilizer is disodium ethylenediaminetetraacetate, which is a commonly used metal ion chelating agent and plays an important role in low-temperature disinfectants. In a low-temperature environment, even trace amounts of metal ions (such as iron, copper, manganese, etc.) may catalyze the decomposition of disinfectant components, and they will preferentially combine with metal ions to ensure that the effective chlorine in the disinfectant can be stably present at low temperatures, thereby improving the durability of the disinfection effect.
[0046] The thickener is xanthan gum, and the viscosity of the xanthan gum is reduced when it is subjected to external force. The xanthan gum thickener can make the disinfectant have good rheological properties at low temperatures. At a suitable concentration, it can make the disinfectant present the characteristics of a pseudoplastic fluid, that is, it is relatively viscous when stationary, but when subjected to a certain external force (such as the pressure of a sprayer), its viscosity is reduced, so that it can be sprayed out smoothly.
[0047] The disinfectant can also be glutaraldehyde, which reacts with amino, carboxyl, sulfhydryl and other groups in microbial proteins to coagulate and denature the proteins. The concentration of the glutaraldehyde is set to 2%-10%. Glutaraldehyde is a highly effective disinfectant that has a good killing effect on bacteria, viruses, spores, etc. Its disinfection mechanism is to coagulate and denature the proteins by reacting with amino, carboxyl, sulfhydryl and other groups in microbial proteins. In the sterilization of pens, a 2% glutaraldehyde solution is generally used. It can be used to immerse and disinfect metal utensils (such as feeders, waterers, etc.) in pens, and can also be used to disinfect other surfaces by spraying.
[0048] Embodiment 4
[0049] A low-temperature antifreeze high-efficiency disinfectant comprises 30 parts of disinfectant, 27 parts of antifreeze, 47 parts of water hardness regulator, 25 parts of corrosion inhibitor, 10 parts of auxiliary agent, 32 parts of stabilizer, 16 parts of thickener and 42 parts of benzalkonium chloride.
[0050] In a preferred embodiment, the disinfectant is hydrogen peroxide. The disinfection principle of hydrogen peroxide is that it has strong oxidizing properties and can produce hydroxyl radicals with bactericidal ability. In a low temperature environment, the reaction rate of hydrogen peroxide will slow down, but it still has a disinfecting effect. It can be used in a low temperature environment of about -30°C.
[0051] In a preferred embodiment, the antifreeze agent is sodium formate, which is also an organic acid salt antifreeze agent. Its freezing point is relatively low. In antifreeze applications, it can form a dual effect of hydrogen bonds and ionic bonds with water molecules, effectively lowering the freezing point of the solution.
[0052] In a preferred embodiment, the water hardness regulator is an ion exchange resin, which is a polymer material with exchangeable ions, and is divided into cation exchange resin and anion exchange resin. Cation exchange resin contains acidic groups (such as sulfonic acid group -SO3H), which can exchange with calcium and magnesium ions in water.
[0053] The corrosion inhibitor is chromate, which is an effective corrosion inhibitor, such as sodium chromate (Na2CrO4) and potassium chromate (K2CrO4). This film is very dense and can prevent corrosive media such as oxygen and water from further contacting the metal, thereby playing an anti-corrosion role.
[0054] The auxiliary agent includes a pH regulator and water. When preparing, water is selected to be room temperature water, and its temperature is set at 20°C-25°C. In a low temperature environment, the activity of the disinfectant may be affected by changes in pH value. The pH regulator includes phosphate, and the phosphate buffer can maintain the pH value of the disinfectant solution within a relatively stable range, thereby ensuring the effectiveness of the disinfectant.
[0055] The stabilizer is disodium ethylenediaminetetraacetate, which is a commonly used metal ion chelating agent and plays an important role in low-temperature disinfectants. In a low-temperature environment, even trace amounts of metal ions (such as iron, copper, manganese, etc.) may catalyze the decomposition of disinfectant components, and they will preferentially combine with metal ions to ensure that the effective chlorine in the disinfectant can be stably present at low temperatures, thereby improving the durability of the disinfection effect.
[0056] The thickener is hydroxyethyl cellulose, which is a commonly used thickener. When added in an appropriate amount, it can increase the consistency of the disinfectant, but will not make it completely impossible to spray. When a small amount of HEC is added, the fluidity of the disinfectant will be slightly worse, but it can still be sprayed through equipment such as a sprayer.
[0057] The disinfectant can also be glutaraldehyde, which reacts with amino, carboxyl, sulfhydryl and other groups in microbial proteins to coagulate and denature the proteins. The concentration of the glutaraldehyde is set to 2%-10%. Glutaraldehyde is a highly effective disinfectant that has a good killing effect on bacteria, viruses, spores, etc. Its disinfection mechanism is to coagulate and denature the proteins by reacting with amino, carboxyl, sulfhydryl and other groups in microbial proteins. In the sterilization of pens, a 2% glutaraldehyde solution is generally used. It can be used to immerse and disinfect metal utensils (such as feeders, waterers, etc.) in pens, and can also be used to disinfect other surfaces by spraying.
[0058] This product uses 5 sets of experimental data during testing. Different concentrations can be used in different environments. See the table below.
[0059] concentration 5％ 10％ 15％ 20％ 25％ Antifreeze temperature -5℃ -11℃ -14℃ -22℃ -35℃
[0060] It can be seen from the table that the higher the concentration of this product, the lower the temperature in which it can be used.
[0061] The disinfection effect of this product on bacteria at different experimental concentrations at -20℃ is shown in the table below.
[0062] concentration 10％ 20％ 25％ Sterilization rate 40％ 50％ 65％
[0063] It can be seen from the table that in an environment of minus 20℃, the higher the concentration of this product, the more obvious the disinfection effect on bacteria, which means that it can still have a disinfection effect in a low temperature environment.
[0064] In summary, this product can be used normally for disinfectants in low-temperature environments, and the disinfectants can still have a bactericidal effect, meeting people's usage needs.
Claims
1. A low-temperature antifreeze efficient disinfectant, characterized in that: The invention comprises 10-40 parts of disinfectant, 20-30 parts of antifreeze agent, 40-50 parts of water hardness regulator, 10-30 parts of anticorrosive agent, 5-15 parts of auxiliary agent, 30-40 parts of stabilizer, 10-25 parts of thickener and 30-50 parts of benzalkonium chloride.
2. A low-temperature antifreeze efficient disinfectant according to claim 1, characterized in that: The disinfectant is selected from one or more of sodium dichloroisocyanurate, sodium hypochlorite, hydrogen peroxide and peracetic acid.
3. A low-temperature antifreeze efficient disinfectant according to claim 2, characterized in that: The antifreeze agent is selected from one or more of acetic acid, propylene glycol, sodium chloride, calcium chloride and sodium formate, and is used to prevent freezing so that the liquid can be used normally.
4. A low-temperature antifreeze efficient disinfectant according to claim 3, characterized in that: The water hardness regulator is selected from one or more of ion exchange resin, trisodium phosphate and chelating agent.
5. A low-temperature antifreeze efficient disinfectant according to claim 4, characterized in that: The corrosion inhibitor is selected from one or more of chromate, phosphate, cyclohexyl carbonate and dicyclohexyl ammonium nitrite.
6. A low-temperature antifreeze efficient disinfectant according to claim 5, characterized in that: The auxiliary agent includes a pH regulator and water. When preparing, the water is selected to be room temperature water, and the temperature is set at 20°C-25°C.
7. A low-temperature antifreeze efficient disinfectant according to claim 6, characterized in that: The stabilizer is selected from one or more of propylene glycol, glycerol, disodium ethylenediaminetetraacetate and borax.
8. A low-temperature antifreeze efficient disinfectant according to claim 7, characterized in that: The thickener is selected from one or more of hydroxyethyl cellulose and xanthan gum. The viscosity of the xanthan gum will decrease when subjected to external force.
9. A low-temperature antifreeze efficient disinfectant according to claim 8, characterized in that: The disinfectant can also be glutaraldehyde, which reacts with amino, carboxyl, sulfhydryl and other groups in microbial protein to coagulate and denature the protein.
10. A low-temperature antifreeze high-efficiency disinfectant according to claim 9, characterized in that: The concentration of glutaraldehyde is set to 2%-10%.