An anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol and its preparation method

Abstract

The present invention discloses an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol and a preparation method thereof, belonging to the daily chemical technology field. Cocamidopropyl betaine, sodium cocoyl glycinate, modified selenium disulfide powder, sodium lauryl polyether sulfate, polydimethylsiloxane, glycerin, preservative, sodium chloride, zinc pyrrolidone carboxylate and deionized water are added to a stirring kettle, stirred evenly at 60-80 °C, cooled to 35-45 °C, and natural extract and hinokitiol are added to the stirring kettle and stirred evenly to obtain an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol. The modified selenium disulfide and hinokitiol are used in combination to synergistically improve the anti-dandruff effect of the shampoo. The modified selenium disulfide uses zeolite powder particles as the matrix and has a unique porous structure, which can effectively adsorb oils, dirt, etc. on the scalp, making the scalp more refreshing. Then, a layer of polydopamine is coated on the outer layer, which helps to reduce the irritation to the scalp and improve the hydrophilicity and dispersion stability of the modified selenium disulfide.

Description

Technical Field

[0001] The present invention belongs to the technical field of daily chemical products, and particularly relates to an anti-dandruff, oil-control and anti-hair-loss shampoo containing hinokitiol and a preparation method thereof. Background Art

[0002] Shampoo is a kind of cosmetic product specially used for basic care of hair and scalp, which is mainly composed of a solvent, a surfactant and other auxiliary agents. The surfactant is a key component in shampoo, which can remove dirt and clean hair, keeping the scalp fresh and clean. Common surfactants include sulfonates, amino acids, soap bases and natural surfactants, etc. Auxiliary agents generally include thickeners, chelating agents, conditioners, preservatives and fragrances, etc., while the solvent is mainly deionized water, serving as a carrier for other components.

[0003] Hinokitiol is usually added to products as an active ingredient in cosmetics. It has broad-spectrum antibacterial and antifungal effects, and has a significant inhibitory effect on a variety of bacteria and fungi. This enables it to play an important anti-corrosion role in cosmetics, extend the shelf life of products, and reduce skin problems caused by microbial contamination.

[0004] Hinokitiol can replace zinc pyrithione (ZPT) in anti-dandruff shampoo to make a transparent anti-dandruff shampoo without turbidity and precipitation, and is also applicable to products such as bath soap and hand sanitizer. However, using a shampoo containing only hinokitiol as the anti-dandruff ingredient has limited effect on stubborn dandruff. Therefore, it generally needs to be added together with other anti-dandruff ingredients. Common ones are selenium disulfide, but selenium disulfide is insoluble in shampoo, has slightly poor dispersibility, and is prone to precipitation after a long storage time, resulting in unstable anti-dandruff effect of the shampoo. Summary of the Invention

[0005] The purpose of the present invention is to provide an anti-dandruff, oil-control and anti-hair-loss shampoo containing hinokitiol and a preparation method thereof. By adding modified selenium disulfide with good dispersion stability and cooperating with hinokitiol, the anti-dandruff effect of the shampoo is synergistically improved.

[0006] The purpose of the present invention can be achieved by the following technical solutions:

[0007] An anti-dandruff, oil-control and anti-hair-loss shampoo containing hinokitiol includes the following components by mass percentage:

[0008] Cocamidopropyl betaine 28 - 32%, Sodium cocoyl glycinate 28 - 32%, Modified selenium disulfide powder 0.2 - 0.3%, Sodium lauryl polyether sulfate 1.5 - 2%, Polydimethylsiloxane 1 - 1.5%, Glycerol 1 - 1.5%, Preservative 0.1%, Natural extract 0.02 - 0.08%, Hinokitiol 0.02 - 0.03%, Sodium chloride 0.02 - 0.03%, Zinc pyrrolidone carboxylate 0.01%, The balance is deionized water.

[0009] Further, the preservative is sodium citrate or sodium salicylate.

[0010] Further, the natural extract is prepared by mixing one or more of Polygonum multiflorum root extract, Moringa oleifera seed extract and Zingiber officinale root extract in any ratio.

[0011] Further, the modified selenium disulfide powder is prepared by the following steps:

[0012] Step 1: Add deionized water, sodium hydroxide and 1,6 - hexanediamine as a template agent into a reaction kettle, stir and mix, then add an aluminum source, stir at 40 - 50 °C and 200 - 300 r / min for 30 - 40 min, then add silica sol with a silica content of 20% and ZSM - 48 molecular sieve raw powder as seeds into the reaction kettle, continue to stir and react for 3 - 4 h, then transfer the reaction solution to a crystallization kettle, stir and crystallize at 100 - 110 °C and 300 - 500 r / min for 20 - 24 h, raise the temperature to 160 - 170 °C, continue to crystallize for 20 - 24 h, filter by suction, wash the filter cake with deionized water until the last washing liquid is neutral, dry in vacuum, transfer to a muffle furnace, calcine at 600 - 650 °C for 8 - 10 h, grind and crush to obtain zeolite powder with a particle size of 1 - 3 μm.

[0013] Step 2: Add sodium sulfide nonahydrate, sulfur, selenium powder and deionized water into a reaction kettle, stir at 200 - 300 r / min for 40 - 60 min to obtain sodium diselenide solution, then add zeolite powder into the reaction kettle, continue to stir for 60 - 80 min, then add hydroiodic acid and ascorbic acid, stir and react at 100 - 110 °C for 60 - 80 min, centrifuge and filter, wash the filter cake with deionized water until the last washing liquid is neutral, dry in vacuum to obtain supported selenium disulfide powder.

[0014] Step 3: Add the supported selenium disulfide powder and deionized water into a reaction kettle, ultrasonically disperse for 20 - 30 min to obtain a supported selenium disulfide dispersion liquid, then adjust the pH value to 8.5 with tris (hydroxymethyl) aminomethane. Under nitrogen protection, add dopamine monomer into the reaction kettle, and stir at 20 - 25 °C and 200 - 300 r / min for 30 - 60 min. Since the zeolite matrix in the supported selenium disulfide powder is negatively charged and the amino group on the surface of the dopamine monomer is positively charged at a pH value of 8.5, the dopamine monomer is adsorbed on the surface of the supported selenium disulfide powder due to π-π stacking. Then, introduce air and continue to stir for 12 - 16 h. The dopamine monomer undergoes oxidative self-polymerization under the action of oxygen to form a layer of polydopamine on the surface of the supported selenium disulfide powder. Centrifuge and filter, wash the filter cake until the last washing liquid is neutral, dry it under vacuum, grind and crush it, and pass through a 2000-mesh sieve to obtain the modified selenium disulfide powder. Further, the mass ratio of deionized water, sodium hydroxide, 1,6-hexanediamine, aluminum source, silica sol, and ZSM-48 molecular sieve raw powder is 380 - 400:1.9 - 2:11 - 12:0.52 - 0.58:300:14.

[0015] Further, the aluminum source is aluminum hydroxide monohydrate or sodium metaaluminate.

[0016] Further, the dosage ratio of sodium sulfide nonahydrate, sulfur, selenium powder, deionized water, zeolite powder, hydroiodic acid, and ascorbic acid is 52.8 mg:7.04 mg:17.38 mg:15 mL:40 - 60 mg:70 mg:50 mg.

[0017] Further, the mass ratio of the supported selenium disulfide powder, deionized water, and dopamine monomer is 15 - 20:100:0.1.

[0018] A preparation method of an anti-dandruff, oil-control, and anti-hair-loss shampoo containing hinokitiol, comprising the following steps:

[0019] Add cocamidopropyl betaine, sodium cocoyl glycinate, modified selenium disulfide powder, sodium lauryl polyether sulfate, polydimethylsiloxane, glycerol, preservative, sodium chloride, zinc pyrrolidone carboxylate, and deionized water into a stirring kettle, stir evenly at 60 - 80 °C, then cool down to 35 - 45 °C, add natural extract and hinokitiol into the stirring kettle, and stir evenly to obtain an anti-dandruff, oil-control, and anti-hair-loss shampoo containing hinokitiol, thus completing the preparation method of the anti-dandruff, oil-control, and anti-hair-loss shampoo containing hinokitiol.

[0020] The beneficial effects of the present invention:

[0021] 1. The anti-dandruff, oil-control, and anti-hair-loss shampoo containing hinokitiol of the present invention is added with modified selenium disulfide, and the modified selenium disulfide and hinokitiol are used together to improve the anti-dandruff effect of the shampoo.

[0022] The modified selenium disulfide uses zeolite powder particles as the matrix, and then a layer of polydopamine is coated on the outer layer. The zeolite powder uses the ZSM-48 molecular sieve raw powder as the seed crystal and has a unique porous structure, which can effectively adsorb oils, dirt, etc. on the scalp, making the scalp more refreshing. The prepared supported selenium disulfide powder particles have a large specific surface area, which helps to improve the stability of the selenium disulfide component, increase the contact area between selenium disulfide per unit mass and the scalp, helps to reduce the dosage of selenium disulfide, reduce the irritation to the scalp, and improve its antibacterial and antidandruff effects. The polydopamine coating layer is natural and mild, which helps to reduce the irritation to the scalp, improve the hydrophilicity and dispersion stability of the modified selenium disulfide, and thus improve the quality of the shampoo product.

[0023] 2. The shampoo of the present invention also contains natural extracts, which helps to promote blood circulation in the scalp, thus contributing to the healthy growth of hair, reducing hair loss, and zinc pyrrolidone carboxylate can also play an oil control effect, helping to improve the anti-hair loss effect of the shampoo. Detailed implementation mode

[0024] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts belong to the scope of protection of the present invention.

[0025] Example 1: This example provides an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol, which is prepared by the following method:

[0026] S1: Add 380 kg of deionized water, 1.9 kg of sodium hydroxide and 11 kg of 1,6-hexanediamine as a template agent to the reaction kettle and stir to mix. Then add 0.52 kg of aluminum oxide monohydrate, stir at 40 °C and 200 r / min for 30 min. Then add 300 kg of silica sol with a silica content of 20% and 14 kg of ZSM-48 molecular sieve raw powder as a seed crystal to the reaction kettle, continue to stir and react for 3 h. Then transfer the reaction solution to the crystallization kettle, stir and crystallize at 100 °C and 300 r / min for 20 h, raise the temperature to 160 °C, continue to crystallize for 20 h, filter by suction, wash the filter cake with deionized water until the last washing solution is neutral, dry in vacuum, transfer to a muffle furnace, calcine at 600 °C for 8 h, grind and crush to obtain zeolite powder with a particle size of 1-3 μm.

[0027] S2: Add 52.8 g of sodium sulfide nonahydrate, 7.04 g of sulfur, 17.38 g of selenium powder, and 15 L of deionized water into a reaction kettle, stir for 40 min under the condition of 200 r / min to obtain a sodium diselenide disulfide solution. Then add 40 g of zeolite powder into the reaction kettle, continue to stir for 60 min, add 70 g of hydroiodic acid and 50 g of ascorbic acid, stir and react for 60 min under the condition of 100 °C, centrifuge and filter, wash the filter cake with deionized water until the last washing liquid is neutral, and dry it under vacuum to obtain supported selenium disulfide powder.

[0028] S3: Add 15 g of supported selenium disulfide powder and 100 g of deionized water into a reaction kettle, ultrasonically disperse for 20 min to obtain a supported selenium disulfide dispersion. Then adjust the pH value to 8.5 with tris (hydroxymethyl) aminomethane. Under nitrogen protection, add 0.1 g of dopamine monomer into the reaction kettle, stir for 30 min under the conditions of 20 °C and 200 r / min, introduce air, continue to stir for 12 h, centrifuge and filter, wash the filter cake until the last washing liquid is neutral, dry it under vacuum, grind and crush it, and pass through a 2000-mesh sieve to obtain modified selenium disulfide powder.

[0029] S4: Stir cocamidopropyl betaine, sodium cocoyl glycinate, modified selenium disulfide powder, sodium lauryl polyether sulfate, polydimethylsiloxane, glycerol, preservative, sodium chloride, zinc pyrrolidone carboxylate, and deionized water in a stirring kettle, stir evenly at 60 °C, then cool down to 35 °C, add natural extract and hinokitiol into the stirring kettle, and stir evenly to obtain an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol.

[0030] Example 2: This example provides an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol, which is prepared by the following method:

[0031] S1: Add 390 kg of deionized water, 1.95 kg of sodium hydroxide, and 11.5 kg of 1,6-hexanediamine as a template agent into a reaction kettle, stir and mix, then add 0.54 kg of aluminum hydroxide monohydrate, stir for 35 min under the conditions of 45 °C and 250 r / min. Then add 300 kg of silica sol with a silica content of 20% and 14 kg of ZSM-48 molecular sieve raw powder as a seed crystal into the reaction kettle, continue to stir and react for 3.5 h. Then transfer the reaction solution to a crystallization kettle, stir and crystallize at 105 °C and 400 r / min for 22 h, raise the temperature to 165 °C, continue to crystallize for 22 h, filter by suction, wash the filter cake with deionized water until the last washing liquid is neutral, dry it under vacuum, transfer it to a muffle furnace, and calcine at 620 °C for 9 h, grind and crush it to obtain zeolite powder with a particle size of 1 - 3 μm.

[0032] S2: Add 52.8 g of sodium sulfide nonahydrate, 7.04 g of sulfur, 17.38 g of selenium powder and 15 L of deionized water into a reaction kettle, stir for 50 min under the condition of 250 r / min to obtain a sodium diselenide disulfide solution. Then add 50 g of zeolite powder into the reaction kettle, continue to stir for 70 min, add 70 g of hydroiodic acid and 50 g of ascorbic acid, stir and react for 70 min under the condition of 105 °C, centrifuge and filter, wash the filter cake with deionized water until the last washing liquid is neutral, and dry it in vacuum to obtain supported selenium disulfide powder.

[0033] S3: Add 18 g of supported selenium disulfide powder and 100 g of deionized water into a reaction kettle, ultrasonically disperse for 25 min to obtain a supported selenium disulfide dispersion. Then adjust the pH value to 8.5 with tris(hydroxymethyl)aminomethane. Under nitrogen protection, add 0.1 g of dopamine monomer into the reaction kettle, stir for 40 min under the conditions of 22 °C and 250 r / min, introduce air, continue to stir for 14 h, centrifuge and filter, wash the filter cake until the last washing liquid is neutral, dry it in vacuum, grind and crush it, and pass through a 2000-mesh sieve to obtain modified selenium disulfide powder.

[0034] S4: Add cocamidopropyl betaine, sodium cocoyl glycinate, modified selenium disulfide powder, sodium lauryl polyether sulfate, polydimethylsiloxane, glycerol, preservative, sodium chloride, zinc pyrrolidone carboxylate and deionized water into a stirring kettle, stir evenly at 70 °C, then cool down to 40 °C, add natural extract and hinokitiol into the stirring kettle, and stir evenly to obtain an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol.

[0035] Example 3: This example provides an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol, which is prepared by the following method:

[0036] S1: Add 390 kg of deionized water, 1.95 kg of sodium hydroxide and 11.5 kg of 1,6-hexanediamine as a template agent into a reaction kettle, stir and mix, then add 0.56 kg of sodium aluminate, stir for 35 min under the conditions of 45 °C and 250 r / min. Then add 300 kg of silica sol with a silica content of 20% and 14 kg of ZSM-48 molecular sieve raw powder as seeds into the reaction kettle, continue to stir and react for 3.5 h. Then transfer the reaction solution to a crystallization kettle, stir and crystallize at 105 °C and 400 r / min for 22 h, raise the temperature to 165 °C, continue to crystallize for 22 h, filter by suction, wash the filter cake with deionized water until the last washing liquid is neutral, dry it in vacuum, transfer it to a muffle furnace, calcine at 630 °C for 9 h, grind and crush it to obtain zeolite powder with a particle size of 1 - 3 μm.

[0037] S2: Add 52.8 g of sodium sulfide nonahydrate, 7.04 g of sulfur, 17.38 g of selenium powder, and 15 L of deionized water into a reaction kettle, stir for 50 min under the condition of 250 r / min to obtain a sodium diselenide disulfide solution. Then add 50 g of zeolite powder into the reaction kettle, continue to stir for 70 min, add 70 g of hydroiodic acid and 50 g of ascorbic acid, stir and react for 70 min under the condition of 105 °C, carry out centrifugal filtration, wash the filter cake with deionized water until the last washing liquid is neutral, and dry it under vacuum to obtain supported selenium disulfide powder.

[0038] S3: Add 18 g of supported selenium disulfide powder and 100 g of deionized water into a reaction kettle, disperse ultrasonically for 25 min to obtain a supported selenium disulfide dispersion. Then adjust the pH value to 8.5 with tris (hydroxymethyl) aminomethane. Under nitrogen protection, add 0.1 g of dopamine monomer into the reaction kettle, stir for 50 min under the conditions of 22 °C and 250 r / min, introduce air, continue to stir for 14 h, carry out centrifugal filtration, wash the filter cake until the last washing liquid is neutral, dry it under vacuum, grind and crush it, and sieve it through a 2000-mesh sieve to obtain modified selenium disulfide powder.

[0039] S4: Add cocamidopropyl betaine, sodium cocoyl glycinate, modified selenium disulfide powder, sodium lauryl polyether sulfate, polydimethylsiloxane, glycerol, preservative, sodium chloride, zinc pyrrolidone carboxylate, and deionized water into a stirring kettle, stir evenly at 70 °C, then cool down to 40 °C, add natural extract and hinokitiol into the stirring kettle, and stir evenly to obtain an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol.

[0040] Example 4: This example provides an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol, which is prepared by the following method:

[0041] S1: Add 400 kg of deionized water, 2 kg of sodium hydroxide, and 12 kg of 1,6-hexanediamine as a template agent into a reaction kettle, stir and mix, then add 0.58 kg of sodium aluminate, stir for 40 min under the conditions of 50 °C and 300 r / min. Then add 300 kg of silica sol with a silica content of 20% and 14 kg of ZSM-48 molecular sieve raw powder as a seed crystal into the reaction kettle, continue to stir and react for 4 h. Then transfer the reaction solution to a crystallization kettle, stir and crystallize at 110 °C and 500 r / min for 24 h, raise the temperature to 170 °C, continue to crystallize for 24 h, carry out suction filtration, wash the filter cake with deionized water until the last washing liquid is neutral, dry it under vacuum, transfer it to a muffle furnace, and calcine it at 650 °C for 10 h, grind and crush it to obtain zeolite powder with a particle size of 1 - 3 μm.

[0042] S2: Add 52.8 g of sodium sulfide nonahydrate, 7.04 g of sulfur, 17.38 g of selenium powder and 15 L of deionized water into a reaction kettle, stir for 60 min under the condition of 300 r / min to obtain a sodium diselenide disulfide solution. Then add 60 g of zeolite powder into the reaction kettle, continue to stir for 80 min, add 70 g of hydroiodic acid and 50 g of ascorbic acid, stir and react for 80 min under the condition of 110 °C, centrifuge and filter, wash the filter cake with deionized water until the last washing liquid is neutral, and dry it under vacuum to obtain supported selenium disulfide powder.

[0043] S3: Add 20 g of supported selenium disulfide powder and 100 g of deionized water into a reaction kettle, ultrasonically disperse for 30 min to obtain a supported selenium disulfide dispersion. Then adjust the pH value to 8.5 with tris (hydroxymethyl) aminomethane. Add 0.1 g of dopamine monomer into the reaction kettle under nitrogen protection, stir for 60 min under the conditions of 25 °C and 300 r / min, introduce air, continue to stir for 16 h, centrifuge and filter, wash the filter cake until the last washing liquid is neutral, dry it under vacuum, grind and crush it, and pass through a 2000-mesh sieve to obtain modified selenium disulfide powder.

[0044] S4: Add cocamidopropyl betaine, sodium cocoyl glycinate, modified selenium disulfide powder, sodium lauryl polyether sulfate, polydimethylsiloxane, glycerol, preservative, sodium chloride, zinc pyrrolidone carboxylate and deionized water into a stirring kettle, stir evenly at 80 °C, then cool down to 45 °C, add natural extract and hinokitiol into the stirring kettle, and stir evenly to obtain an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol.

[0045] In Examples 1-4, for the anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol, the specific ratios of each component are shown in Table 1 by mass percentage:

[0046] Table 1

[0047] Component Name Example 1 Example 2 Example 3 Example 4 Cocamidopropyl Betaine 28% 29% 30% 32% Sodium Cocoyl Glycinate 32% 31% 30% 28% Modified Selenium Disulfide Powder 0.2% 0.25% 0.25% 0.3% Sodium Laureth Sulfate 1.5% 1.8% 1.8% 2% Polydimethylsiloxane 1% 1.2% 1.2% 1.5% Glycerin 1% 1.2% 1.2% 1.5% Preservative Sodium Citrate 0.1% Sodium Citrate 0.1% Sodium Salicylate 0.1% Sodium Salicylate 0.1% Natural Extract Polygonum Multiflorum Root Extract 0.04% Moringa Seed Extract 0.02% Ginger Root Extract 0.06% Polygonum Multiflorum Root Extract 0.02%, Moringa Seed Extract 0.02%, Ginger Root Extract 0.04% Platycladiol 0.02% 0.025% 0.03% 0.03% Sodium Chloride 0.02% 0.025% 0.025% 0.03% Zinc Pyrrolidonecarboxylate 0.01% 0.01% 0.01% 0.01% Deionized Water 36.11% 35.47% 35.325% 34.45

[0048] The raw materials in the examples are all commercially available products.

[0049] Comparative Example 1: On the basis of Example 4, without going through the treatment of step S3, directly use the supported selenium disulfide powder with the same mass in step S2 to replace the modified selenium disulfide powder in step S4, and keep the rest of the steps unchanged to prepare a shampoo.

[0050] Comparative Example 2: On the basis of Example 4, directly use commercially available selenium disulfide powder with a particle size of about 5 μm and the same mass to replace the modified selenium disulfide powder in step S3 in step S4 to prepare a shampoo.

[0051] Comparative Example 3: On the basis of Example 4, without adding hinokitiol, keep the rest of the steps unchanged to prepare a shampoo.

[0052] Performance tests were carried out on Examples 1 - 4 and Comparative Examples 1 - 3. Referring to the suspension quantitative method in QB / T 2738 - 2012, the antibacterial effects of the shampoos in different examples were examined. If the antibacterial rate > 90%, it can be considered that the shampoo has a strong antibacterial effect. In the experimental group, the shampoo components were added, and the shampoo was stored in a long test tube and left standing vertically at room temperature for 90 days. One group added the surface shampoo stock solution, and the other group added the bottom shampoo stock solution. The control group did not add shampoo components. The strain used was Malassezia furfur (ATCC 44344), and the action time was 1 min. The results of the antibacterial effects are shown in the following table:

[0053] Table 2 Results of antibacterial effects of shampoos in each group

[0054]

[0055] As can be seen from Table 1, the shampoos in the examples have good antibacterial effects on Malassezia furfur, and the antibacterial rate > 99.9%. In Comparative Example 1, the antibacterial effect of the bottom shampoo stock solution on Malassezia furfur is better than that of the surface shampoo stock solution because the selenium disulfide component in Comparative Example 1 settled to the bottom of the test tube, indicating that the dispersion stability of the modified selenium disulfide was improved after being coated with polydopamine. The results of Comparative Example 2 show that not only can the dispersion stability of the selenium disulfide component be improved by zeolite loading and polydopamine coating, but also its antibacterial effect can be improved. It may be that the zeolite particles played an adsorption role and increased the contact rate between the modified selenium disulfide and the bacteria. Comparative Example 3 shows that hinokitiol also has a certain antibacterial effect on Malassezia furfur. In the examples of the present invention, the modified selenium disulfide and hinokitiol synergistically play an antibacterial and anti-dandruff role.

[0056] It should be noted that in this article, terms such as "including", "comprising" or any other variant thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements but also includes other elements not explicitly listed, or also includes elements inherent to such a process, method, article or device.

[0057] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A dandruff-removing, oil-control and anti-hair loss shampoo containing hinokitiol, characterized in that It comprises the following components by mass percentage: Cocamidopropyl betaine 28 - 32%, Sodium cocoyl glycinate 28 - 32%, Modified selenium disulfide powder 0.2 - 0.3%, Sodium lauryl polyether sulfate 1.5 - 2%, Polydimethylsiloxane 1 - 1.5%, Glycerol 1 - 1.5%, Preservative 0.1%, Natural extract 0.02 - 0.08%, Hinokitiol 0.02 - 0.03%, Sodium chloride 0.02 - 0.03%, Zinc pyrrolidone carboxylate 0.01%, and the balance is deionized water; The modified selenium disulfide powder is prepared by the following steps: Add the supported selenium disulfide powder and deionized water into a reaction kettle, ultrasonically disperse for 20 - 30 min, then adjust the pH value to 8.5 with tris(hydroxymethyl)aminomethane. Under nitrogen protection, add dopamine monomer into the reaction kettle, stir at 20 - 25 °C and 200 - 300 r / min for 30 - 60 min, then continue to stir for 12 - 16 h by introducing air, centrifuge and filter, wash the filter cake until the last washing liquid is neutral, dry in vacuum, grind and crush, and pass through a 2000 - mesh sieve to obtain the modified selenium disulfide powder; The supported selenium disulfide powder is prepared by the following steps: Add deionized water, sodium hydroxide and 1,6 - hexanediamine into a reaction kettle, stir and mix, then add an aluminum source, stir at 40 - 50 °C and 200 - 300 r / min for 30 - 40 min, then add silica sol with a silica content of 20% and ZSM - 48 molecular sieve raw powder, continue to stir and react for 3 - 4 h, transfer the reaction solution to a crystallization kettle, stir and crystallize at 100 - 110 °C and 300 - 500 r / min for 20 - 24 h, raise the temperature to 160 - 170 °C, continue to crystallize for 20 - 24 h, filter by suction, wash the filter cake with deionized water until the last washing liquid is neutral, dry in vacuum, transfer to a muffle furnace, calcine at 600 - 650 °C for 8 - 10 h, grind and crush to obtain zeolite powder with a particle size of 1 - 3 μm; Add sodium sulfide nonahydrate, sulfur, selenium powder and deionized water into a reaction kettle, stir at 200 - 300 r / min for 40 - 60 min, then add zeolite powder, continue to stir for 60 - 80 min, then add hydroiodic acid and ascorbic acid, stir and react at 100 - 110 °C for 60 - 80 min, centrifuge and filter, wash the filter cake with deionized water until the last washing liquid is neutral, dry in vacuum to obtain the supported selenium disulfide powder.

2. The anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol according to claim 1, wherein The preservative is sodium citrate or sodium salicylate.

3. The anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol according to claim 1, characterized in that, The natural extract is prepared by mixing one or more of polygonum multiflorum root extract, moringa seed extract and ginger root extract in any ratio.

4. The anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol according to claim 1, wherein, The mass ratio of the supported selenium disulfide powder, deionized water and dopamine monomer is 15 - 20:100:0.

1.

5. The anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol according to claim 1, characterized in that, The dosage ratio of sodium sulfide nonahydrate, sulfur, selenium powder, deionized water, zeolite powder, hydroiodic acid and ascorbic acid is 52.8 mg:7.04 mg:17.38 mg:15 mL:40 - 60 mg:70 mg:50 mg.

6. The anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol according to claim 1, wherein The mass ratio of the deionized water, sodium hydroxide, 1,6-hexanediamine, aluminum source, silica sol and ZSM-48 molecular sieve raw powder is 380-400: 1.9-2: 11-12: 0.52-0.58: 300:

14.

7. A dandruff-removing, oil-control and anti-hair loss shampoo containing hinokitiol according to claim 1, characterized in that, The aluminum source is aluminum hydroxide monohydrate or sodium aluminate.

8. The preparation method of an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol according to claim 1, characterized in that, It includes the following steps: Put cocamidopropyl betaine, sodium cocoyl glycinate, modified selenium disulfide powder, sodium lauryl polyether sulfate, polydimethylsiloxane, glycerin, preservative, sodium chloride, zinc pyrrolidone carboxylate and deionized water into a stirring kettle, stir evenly at 60-80 °C, cool down to 35-45 °C and add natural extract and hinokitiol, stir evenly to obtain an anti-dandruff, oil-control and anti-hair loss shampoo containing hinokitiol.

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