Method and system for monitoring ESWL treatment effect in real time

Abstract

The invention discloses a method and a system for monitoring an ESWL treatment effect in real time. The method comprises the following steps: S1, generating shock waves by using a stone crusher, focusing the shock waves on a target stone, and inducing to generate a specific sound pressure waveform signal; and S2, capturing the sound pressure waveform signal by using a hydrophone, and converting the sound pressure waveform signal into an electric signal. Then, the electric signal is transmitted to a data acquisition module, and preliminary signal receiving and conversion are completed; and S3, the stone crusher sends a trigger signal to the data acquisition module through a special trigger line. At the rising edge moment of the trigger signal, the data acquisition module is activated and starts to receive electric signal data converted by the hydrophone; and S4, establishing connection between the data acquisition module and a computer, and then processing and analyzing the data by the computer so as to evaluate the treatment effect of the ESWL. The ESWL treatment effect can be monitored in real time, the treatment effect is fed back, and then a doctor can judge the treatment progress and effect.

Description

Technical Field

[0001] The present invention relates to the field of medical technology, and in particular to a method and system for real-time monitoring of ESWL treatment effects. Background Art

[0002] Extracorporeal shock wave lithotripsy is a non-invasive treatment method mainly used to treat urinary stones, especially for kidney stones and ureteral stones. Currently, ESWL has become the standard method for treating kidney stones with a diameter of less than 2.0 cm or a surface area of ​​less than 300 mm2. With the further exploration of the stone-free rate of ESWL treatment, real-time monitoring of the treatment effect of ESWL has also received increasing attention.

[0003] In the prior art, X-ray or ultrasound B-scan imaging is used to locate the stone and check whether it remains at the focus of the lithotripter during treatment, but both imaging methods are not very effective in monitoring the treatment effect during treatment. Therefore, it is difficult for ESWL operators to judge the progress and effect of the treatment, and thus it is impossible to determine whether to continue treatment or adjust the treatment plan, thereby prolonging the patient's treatment cycle and reducing their stone-free rate.

[0004] In summary, in view of the fact that real-time monitoring of the therapeutic effect of extracorporeal shock wave lithotripsy is of great value to improving its stone-free rate, the present invention proposes a method and system for real-time monitoring of the therapeutic effect of ESWL, which uses the correlation between acoustic parameters in the ESWL process and the therapeutic effect, and uses corresponding methods and systems to monitor the therapeutic effect of ESWL in real time to help ESWL operators make decisions. Summary of the invention

[0005] In view of the problems existing in the prior art, the purpose of the present invention is to provide a method and system for real-time monitoring of the ESWL treatment effect, so as to provide the ESWL operator with relevant information on the treatment effect, thereby helping the ESWL operator to make decisions and improve the stone-free rate of ESWL.

[0006] In order to achieve the above object, the present invention provides the following scheme:

[0007] A method for real-time monitoring of ESWL treatment effects, comprising the following steps:

[0008] S1. Use the lithotripsy machine to generate shock waves of preset times, frequencies and energy levels, and precisely focus on the target stone to induce a specific sound pressure waveform signal.

[0009] S2, using a hydrophone device to capture the above sound pressure waveform signal and convert it into an electrical signal. Subsequently, the electrical signal data is transmitted to a data acquisition module to complete preliminary signal reception and conversion.

[0010] S3, the lithotripter sends a trigger signal to the data acquisition module through the trigger line. At the rising edge of the trigger signal, the data acquisition module is activated and starts to receive the electrical signal data converted by the hydrophone.

[0011] S4. Use the universal interface bus to achieve a stable connection between the data acquisition module and the computer. The data acquisition module transmits the acquired electrical signal data to the computer in real time. The computer processes and analyzes the data, including steps such as feature value extraction, to evaluate the therapeutic effect of ESWL.

[0012] The present invention is beneficial in that:

[0013] The present invention can achieve real-time monitoring of the ESWL treatment effect and feedback of the treatment effect, so that doctors can judge the progress and effect of the treatment, thereby adjusting the treatment strategy to ensure that the best treatment effect is achieved in the shortest time. This efficient treatment method helps to shorten the patient's treatment cycle and reduce the patient's pain and economic burden. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 A flow chart of a method for real-time monitoring of ESWL treatment effects according to the present invention;

[0015] Figure 2 A schematic diagram of a system for real-time monitoring of ESWL treatment effects according to the present invention. DETAILED DESCRIPTION

[0016] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0017] like Figure 1 As shown, the embodiment of the present application provides a method for real-time monitoring of ESWL treatment effect, the method comprising the following steps:

[0018] S1. Use the lithotripsy machine to generate shock waves of preset times, frequencies and energy levels, and precisely focus on the target stone to induce a specific sound pressure waveform signal.

[0019] S2, using a hydrophone device to capture the above sound pressure waveform signal and convert it into an electrical signal. Subsequently, the electrical signal data is transmitted to a data acquisition module to complete preliminary signal reception and conversion.

[0020] S3, the lithotripter sends a trigger signal to the data acquisition module through the trigger line. At the rising edge of the trigger signal, the data acquisition module is activated and starts to receive the electrical signal data converted by the hydrophone.

[0021] S4. Use the universal interface bus to achieve a stable connection between the data acquisition module and the computer. The data acquisition module transmits the acquired electrical signal data to the computer in real time. The computer processes and analyzes the data, including steps such as feature value extraction, to evaluate the therapeutic effect of ESWL.

[0022] As an embodiment of the present invention, the shock wave of preset frequency and energy level in S1 is preset according to the type, size, location of the target stone and the physical condition of the patient.

[0023] As an embodiment of the present invention, the hydrophone device in S2 has high sensitivity and can accurately capture the sound pressure waveform signal p(t) induced by the shock wave and convert it into electrical signal data with a high signal-to-noise ratio.

[0024] As an embodiment of the present invention, the electrical signal is subdivided into two specific signal areas: the first area is the stone reflection wave area: the signal in this area is mainly composed of the reflection wave generated when the shock wave acts on the target stone. The second area is the cavitation bubble rupture signal area: the signal in this area originates from the cavitation phenomenon caused by the shock wave propagating in the water, that is, the water molecules are stretched to form tiny bubbles, and then these bubbles rupture under the action of the shock wave to generate the signal.

[0025] As an implementation mode of the present invention, the trigger line in S3 has a low delay characteristic to ensure that the data acquisition module can be immediately activated and start receiving data at the rising edge of the trigger signal.

[0026] As an embodiment of the present invention, the computer described in S4 also includes pre-processing steps such as filtering and denoising the electrical signal data to improve the accuracy of subsequent feature value extraction.

[0027] As an implementation manner of the present invention, the extraction of the characteristic value includes the peak values ​​m1 and m2 of two regions of the electrical signal, and the time difference tc between the two regions.

[0028] As an implementation mode of the present invention, the tc can be calculated by tc=t2-t1. t1 and t2 represent the duration of two regions of the electrical signal respectively.

[0029] Among them, t1, t2 are Calculation can be obtained. i,max and t i,minIndicates the starting point and end point of the corresponding area, i indicates the number of the area, i=1 or 2.

[0030] As an embodiment of the present invention, the I i (t)Through It can be calculated that p(t) represents the sound pressure waveform signal.

[0031] As an embodiment of the present invention, the therapeutic effect of ESWL described in S4 can be judged according to a set of rules based on acoustic parameters developed in clinical medicine. The set of rules based on acoustic parameters developed in clinical medicine is that the effective requirement of a single shock wave is 0.4<m2 / m1<0.8 and tc>100μs, and the requirement for successful treatment is that the number of effective shock waves is greater than or equal to 50% of the preset number of shock waves.

[0032] in Figure 2 This is a schematic diagram of a system for real-time monitoring of ESWL treatment effects of the present invention. The device includes an operating table 1, a lithotripter 2, a shock wave source 3, a fixing assembly 4, a hydrophone 5, a hydrophone cable 6, a trigger line 7, a data acquisition module 8, and a computer 9.

[0033] The operating table is a medical device specially designed to support the patient's body position during extracorporeal shock wave lithotripsy treatment and to ensure the safety and comfort of the treatment process.

[0034] The lithotripsy is used to generate shock waves of preset frequency and energy level and precisely focus on the target stone.

[0035] The hydrophone is used to receive the electrical signal data converted by the hydrophone device.

[0036] The trigger line is connected between the lithotripter and the data acquisition module, and is used to send a trigger signal to the data acquisition module to activate its receiving function.

[0037] The data acquisition module is used to receive the electrical signal data converted by the hydrophone device.

[0038] The computer is connected to the data acquisition module via a universal interface bus and is used to receive and process electrical signal data to evaluate the therapeutic effect of ESWL.

[0039] First, the patient lies flat on the operating table. The ESWL operator sets a certain number of shocks, frequency and energy level of shock waves according to the actual situation. The shock waves will focus on the patient's stones. With each shock, the sound pressure signal is converted into electrical signal data through the hydrophone, completing the initial signal reception and conversion. Then the lithotripter sends a trigger signal to the data acquisition module through the trigger line. At the rising edge of the trigger signal, the data acquisition module is activated and begins to receive the electrical signal data converted by the hydrophone. Finally, the electrical signal data is transmitted to the computer, and then the computer processes and analyzes the data through software. After completing the data processing and analysis, the computer intuitively displays the effect evaluation report of this treatment to the ESWL operator through the user interface. The report may contain key information such as the hitting of the stone, the rupture of the stone, and the treatment effect. Based on these detailed feedback, the ESWL operator can make more accurate and scientific decisions, including whether to continue treatment, adjust shock wave parameters, or take other necessary intervention measures.

[0040] The above description of the disclosed embodiments enables one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A method for real-time monitoring of ESWL treatment effects, characterized in that: The steps include: S1. Use a lithotripter to generate shock waves of preset times, frequencies and energy levels, and precisely focus on the target stone to induce an acoustic pressure waveform signal; S2, using a hydrophone device to capture the above-mentioned sound pressure waveform signal and convert it into an electrical signal form; Subsequently, the electrical signal data is transmitted to the data acquisition module to complete the initial signal reception and conversion; S3, the lithotripter sends a trigger signal to the data acquisition module through the trigger line; at the rising edge of the trigger signal, the data acquisition module is activated and starts to receive the electrical signal data converted by the hydrophone; S4. The data acquisition module transmits the acquired electrical signal data to the computer in real time. The computer processes and analyzes the data, including the extraction of characteristic values, to evaluate the therapeutic effect of ESWL.

2. A method for real-time monitoring of ESWL treatment effect according to claim 1, characterized in that: In step S1, the shock waves of the preset frequency and energy level are preset according to the type, size, location of the target stone and the physical condition of the patient.

3. A method for real-time monitoring of ESWL treatment effect according to claim 1, characterized in that: In step S2, the hydrophone device has high sensitivity and can accurately capture the sound pressure waveform signal p(t) induced by the shock wave and convert it into electrical signal data with a high signal-to-noise ratio.

4. A method for real-time monitoring of ESWL treatment effect according to claim 3, characterized in that: The electrical signal is subdivided into two specific signal regions: The first area is the stone reflection wave area: the signal in this area is mainly composed of the reflection wave generated when the shock wave acts on the target stone; The second area is the cavitation bubble rupture signal area: the signal in this area comes from the cavitation phenomenon caused by the propagation of shock waves in the water, that is, the water molecules are stretched to form tiny bubbles, and then these bubbles burst under the action of shock waves to produce signals.

5. A method for real-time monitoring of ESWL treatment effect according to claim 1, characterized in that: In step S3, the trigger line has a low latency characteristic to ensure that the data acquisition module can be immediately activated and start receiving data at the rising edge of the trigger signal.

6. A method for real-time monitoring of ESWL treatment effects according to claim 1, characterized in that: In step S4, the computer also includes a preprocessing step of filtering and denoising the electrical signal data to improve the accuracy of subsequent feature value extraction.

7. A method for real-time monitoring of ESWL treatment effect according to claim 1 or 4, characterized in that: The feature value extraction includes the peak values ​​m1 and m2 of the two regions of the electrical signal, and the time difference t between the two regions. c .

8. A method for real-time monitoring of ESWL treatment effects according to claim 7, characterized in that: The c By t c =t2-t1, t 1， t2 represents the duration of the two regions of the electrical signal; Among them, t 1， t2 pass Calculation can be obtained; t i,max and t i,min Indicates the starting point and end point of the corresponding area, i indicates the number of the area, i=1 or 2.

9. A method for real-time monitoring of ESWL treatment effects according to claim 8, characterized in that: The I i (t)Through It can be calculated that p(t) represents the sound pressure waveform signal.

10. A method for real-time monitoring of ESWL treatment effects according to claim 1, characterized in that: In step S4, the therapeutic effect of ESWL is evaluated according to a set of rules based on acoustic parameters developed in clinical medicine to further judge the therapeutic effect of ESWL. The rule is that the effective requirement of a single shock wave is 0.4<m2 / m1<0.8 and tic>100μs, and the requirement for successful treatment is that the number of effective shock waves is greater than or equal to 50% of the preset number of shock waves.

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