Traditional Chinese medicine weight-losing formula

Abstract

The invention relates to a traditional Chinese medicine weight-losing formula which comprises the following raw materials: 8-15g of hawthorn; 6 to 12g of semen cassiae; 6-12g of lotus leaf; 10 to 20g of poria cocos; 8 to 12g of rhizoma alismatis; 5-12g of rhizoma atractylodis macrocephalae or pericarpium citri reticulatae; 1-5g of cinnamon; 1 to 15g of dwarf lilyturf tuber; 1-12 g of lily; 1-10 g of coptis chinensis; and 1-5g of radix polygoni multiflori preparata. According to the traditional Chinese medicine formula, the overall weight losing concept is that firstly, the medicine controls appetite, secondly, digestion can be promoted, food retention can be reduced, smooth bowel relaxing and diuresis can be achieved, and meanwhile the traditional Chinese medicine formula can be suitable for special crowds such as a yang-deficiency system, a phlegm-dampness constitution and a yin-deficiency system. The invention provides a traditional Chinese medicine weight-losing formula capable of adapting to individual people.

Description

Technical Field

[0001] The invention relates to a Chinese medicine formula, in particular to a Chinese medicine weight loss formula. Background Art

[0002] With the change of modern lifestyle, obesity has become a global health challenge. Obesity not only affects the appearance of an individual, but is also closely related to a variety of chronic diseases such as cardiovascular disease and diabetes. Traditional weight loss methods, such as dieting and exercise, are often difficult to stick to for a long time and have limited effects. Although some weight loss drugs have significant effects in the short term, long-term use may cause side effects such as liver and kidney damage and intestinal dysfunction. Therefore, developing a safe and effective weight loss method has become an important research direction in the field of medicine and health.

[0003] Although existing weight loss products and methods can solve the problem of obesity to a certain extent, there are still many shortcomings. First, the existing weight loss drugs and health products are often unstable and prone to rebound, and long-term use may lead to side effects such as liver and kidney damage and intestinal dysfunction. Secondly, the existing weight loss methods lack personalization and cannot be adjusted according to individual differences, resulting in limited weight loss effects. In addition, some traditional weight loss methods such as acupuncture and massage, although relatively safe, have limited effects and are difficult to meet the needs of modern people's fast-paced lifestyles. Therefore, the development of a safe, effective, and personalized Chinese medicine weight loss formula has important practical significance and application value. Summary of the invention

[0004] The purpose of the invention is to provide a Chinese medicine weight loss formula that can adapt to different groups of people.

[0005] In order to solve the above technical problems, the technical solution of a Chinese medicine weight loss formula in the present invention is as follows: A Chinese medicine weight loss formula comprises the following raw materials: 8-15g of hawthorn; 6-12g of cassia seed; 6-12g of lotus leaf; 10-20g of tuckahoe; 8-12g of oriental rhizome; 8-12g of atractylodes macrocephala; 1-5g of cinnamon bark; 1-15g of ophiopogon japonicus; 1-12g of lily; 1-10g of coptis root; and 1-10g of processed radix polygoni multiflori.

[0006] Furthermore, the formula includes the following raw materials: 10-15g of hawthorn; 6-8g of cassia seed; 6-12g of lotus leaf; 12-20g of Poria; 10-12g of Alisma; 10-12g of Atractylodes; 3-5g of cinnamon; 1-2g of Ophiopogon; 1-2g of Lilium; 1-10g of Coptis chinensis; and 1-10g of processed Polygonum multiflorum.

[0007] Furthermore, the formula includes the following raw materials: 8-10g of hawthorn; 6-12g of cassia seed; 6-12g of lotus leaf; 10-20g of Poria; 8-12g of Alisma; 8-12g of Atractylodes; 1-5g of cinnamon; 10-15g of Ophiopogon; 8-12g of lily; 1-10g of Coptis chinensis; and 1-10g of processed Polygonum multiflorum.

[0008] The beneficial effects of the present invention are as follows: the overall weight loss concept of the Chinese medicine formula in the present invention is that the medicine first controls appetite, secondly promotes digestion, reduces food accumulation, and also achieves smooth bowel movements and diuresis. At the same time, it is also suitable for special groups of people, such as those with yang deficiency, phlegm-dampness, and yin deficiency. The specific pharmacological effects are as follows: 1) The organic acid in hawthorn can promote gastric juice secretion, enhance digestive enzyme activity, and help digestion. At the same time, the flavonoids in hawthorn have antioxidant and blood lipid regulating effects; 2) Anthraquinone compounds in Cassia seed can stimulate intestinal peristalsis, promote defecation, and reduce intestinal absorption of fat; 3) Nuciferine in lotus leaves can inhibit fat absorption and regulate fat metabolism; 4) Poria cocos has diuretic, sedative, anti-tumor, blood sugar lowering and myocardial contractility increasing effects; 5) Alisma orientalis has the functions of promoting diuresis and dispelling dampness, relieving heat and relieving stranguria, and can reduce serum total cholesterol and triglyceride levels; 6) Atractylodes macrocephala has the effects of strengthening the spleen and replenishing qi, drying dampness and promoting diuresis, stopping sweating, and calming the fetus; 7) Cinnamon bark has the functions of replenishing fire and yang, guiding fire back to its source, dispelling cold and relieving pain, and promoting blood circulation and menstruation; 8) Ophiopogon japonicus has the effects of nourishing yin, promoting body fluid, moistening the lungs and clearing the heart; 9) Lily has the effects of nourishing yin and moistening the lungs, clearing the heart and calming the mind; 10) Coptis chinensis has the effects of clearing away heat and dampness, purging fire and detoxifying, and suppressing appetite. The bitter and cold nature of Coptis chinensis can clear away dampness and heat, while the sour and warm nature of Hawthorn can invigorate the stomach and help digestion. The combination of the two can partially neutralize the coldness of Coptis chinensis and reduce the stimulation of the spleen and stomach by Coptis chinensis. The digestion-promoting and relieving effects of Hawthorn can alleviate the bitterness and coldness of Coptis chinensis, thus forming a complementary relationship. Atractylodes macrocephala can also neutralize the coldness of Coptis chinensis. 11) The processed Polygonum multiflorum has the function of nourishing the liver and kidneys, and improving the essence and blood. It can work together with Atractylodes macrocephala to alleviate the damage caused by Coptis chinensis to the liver and kidneys. DETAILED DESCRIPTION

[0009] In order to facilitate the understanding of the present invention, the present invention will be described in more detail below in conjunction with specific embodiments. However, the present invention can be implemented in many different forms and is not limited to the embodiments described in this specification. On the contrary, the purpose of providing these embodiments is to make the understanding of the disclosure of the present invention more thorough and comprehensive.

[0010] It should be noted that, unless otherwise defined, all technical and scientific terms used in this specification have the same meaning as those commonly understood by those skilled in the art of the present invention. The terms used in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention.

[0011] Embodiment 1 of a Chinese medicine weight loss formula of the present invention: The formula includes the following raw materials: 10g of hawthorn; 11g of cassia seed; 8g of lotus leaf; 15g of Poria; 10g of Alisma orientalis; 8g of Atractylodes macrocephala; 1g of cinnamon bark; 8g of Ophiopogon japonicus; 5g of lily; 7g of Coptis chinensis; and 3g of processed Polygonum multiflorum.

[0012] When prescribing Chinese medicine prescriptions, the individual's physical condition should be evaluated through the Chinese medicine methods of looking, smelling, asking, and palpating, such as yang deficiency constitution, yin deficiency constitution, and phlegm-dampness constitution; the patient's health status should be assessed, including liver and kidney function tests, blood sugar and blood lipid tests, and gastrointestinal function assessments; the patient's living habits should be assessed to understand the individual's dietary preferences, exercise habits, sleep conditions, etc.

[0013] For obese people with yang deficiency and mild liver and kidney damage, the dosage of Cassia seed can be reduced to 6g, the dosage of Atractylodes macrocephala can be increased to 12g, and cinnamon bark can be increased by 3-5g to warm the yang and dispel the cold.

[0014] The corresponding embodiment 2 of a traditional Chinese medicine weight loss formula in the present invention is: the formula includes the following raw materials, hawthorn 10g; cassia seed 6g; lotus leaf 8g; Poria 15g; Alisma orientalis 10g; Atractylodes macrocephala 12g; cinnamon bark 4g; Ophiopogon japonicus 2g; lily 5g; Coptis chinensis 5g; processed Polygonum multiflorum 2g.

[0015] For obese people with phlegm-damp constitution and indigestion symptoms, the dosage of Poria cocos can be increased to 20 grams, the dosage of lotus leaf to 12 grams, and the dosage of hawthorn can be reduced to 8 grams.

[0016] The corresponding embodiment 3 of a Chinese medicine weight loss formula in the present invention is: the formula comprises the following raw materials, Hawthorn 8g; Cassia seed 10g; Lotus leaf 12g; Poria 20g; Alisma orientalis 8g; Atractylodes macrocephala 6g; Cinnamon bark 4g; Ophiopogon japonicus 2g; Lilium 5g; Coptis chinensis 5g; Processed Polygonum multiflorum 2g.

[0017] For obese people with Yin deficiency and poor sleep, the dosage of hawthorn can be reduced to 8 grams, and the dosage of Ophiopogon japonicus can be increased to 10-15 grams and the dosage of lily can be increased to 8-12 grams to nourish Yin, clear heat, nourish the heart and calm the mind.

[0018] The corresponding embodiment 4 of a traditional Chinese medicine weight loss formula of the present invention is: hawthorn 8g; cassia seed 10g; lotus leaf 12g; Poria 10g; Alisma orientalis 8g; Atractylodes macrocephala 6g; cinnamon bark 4g; Ophiopogon japonicus 12g; lily 10g; Coptis chinensis 5g; processed Polygonum multiflorum 2g.

[0019] The overall weight loss mechanism of the present invention is: first, the drug controls appetite to control energy intake; secondly, it can promote digestion, reduce food accumulation, deal with the patient's existing physical burden, and achieve smooth bowel movements and diuresis. At the same time, it must be suitable for special groups of people, such as those with yang deficiency, phlegm-dampness, yin deficiency, etc.

[0020] Animal model test: Rats were selected as animal models and randomly divided into a control group and an experimental group. The control group was given ordinary feed, and the experimental group was given a high-fat feed to establish an obesity model. After the model was successfully established, the experimental group was given the Chinese medicine weight loss formula for intervention. Changes in indicators such as body weight, body fat content, blood sugar, and blood lipids in the rats were observed. The test period was 8-12 weeks, preferably 10 weeks. Take the Chinese medicine formula in Example 1 as an example: Test steps: Step 1: Select 60 healthy male SD rats, and after one week of adaptive feeding, randomly divide them into a control group (20 rats) and an experimental group (40 rats).

[0021] Step 2: The control group was given ordinary feed, and the experimental group was given a high-fat feed (containing 80% ordinary feed, 10% lard, and 10% egg yolk powder) for 8 weeks to establish an obesity model.

[0022] Step 3: After the model was successfully established, the experimental group was randomly divided into a low-dose group (10), a medium-dose group (10) and a high-dose group (20). The low-dose group was given 5 g / kg body weight / day of the Chinese medicine weight loss formula, the medium-dose group was given 10 g / kg body weight / day, and the high-dose group was given 15 g / kg body weight / day, all by gavage, and the control group was given an equal volume of normal saline.

[0023] Step 4: During the dosing period, the rats were weighed weekly, and their body length and waist circumference were measured every 2 weeks to calculate the Lee's index (Lee's index = body weight (g) × 10³ / body length (cm)).

[0024] Step 5: After the experiment, the rats were killed, blood was taken to test blood sugar and blood lipid (total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol) levels, and liver and adipose tissue were taken for pathological section examination.

[0025] Test results: 1) Body weight and body fat content: Compared with the control group, the body weight and body fat content of the rats in the experimental group were significantly reduced in a dose-dependent manner, and the weight loss effect of the high-dose group was the most significant.

[0026] 2) Blood sugar and blood lipids: The blood sugar and blood lipid levels of rats in the experimental group were significantly improved, especially in the high-dose group, the levels of total cholesterol, triglycerides and low-density lipoprotein cholesterol were significantly reduced, and the level of high-density lipoprotein cholesterol was significantly increased.

[0027] 3) Pathological sections: The liver of the rats in the control group showed obvious fatty degeneration and the volume of fat cells increased. The liver fatty degeneration of the rats in the experimental group was alleviated and the volume of fat cells decreased.

[0028] Human clinical trials, Each formulation in Examples 1, 2, 3 and 4 is used in a population with corresponding symptoms, and the population usage of each formulation is not less than 10 people. Before use, all patients are given a comprehensive physical examination, including the detection of height, weight, BMI, waist circumference, hip circumference, blood pressure, blood sugar, blood lipids, liver and kidney function and other indicators. The patient is fed twice a day, 150 ml each time. A treatment course is three months.

[0029] During the period of taking the formula, follow-up visits were conducted every two weeks to measure body weight, body fat percentage, waist circumference, hip circumference and other indicators to observe for adverse reactions. After the trial, a physical examination was conducted here to test various indicators and compare them with those before the trial.

[0030] Four groups of tests corresponding to the four embodiment formulations: 1) Body weight and body fat percentage: The body weight and body fat percentage of the treatment group were significantly reduced, with an average weight loss of 5-8 kg and a body fat percentage reduction of 5%-8%.

[0031] 2) Body circumference: Waist and hip circumferences were significantly reduced, with the average waist circumference reduced by 5-8 cm and the hip circumference reduced by 3-5 cm.

[0032] 3) Health indicators: blood sugar and blood lipid levels are improved, and blood pressure is stable.

[0033] 4) Adverse reactions: Only a few volunteers in the treatment group experienced mild gastrointestinal discomfort, such as nausea and diarrhea. The symptoms were relieved after adjusting the medication, and no serious adverse reactions occurred.

[0034] Through the above animal model tests and human clinical trials, the weight loss effect and safety of this Chinese medicine weight loss formula have been fully verified, providing a strong basis for its clinical application. At the same time, personalized adjustments based on individual physique and health conditions can further improve the weight loss effect and safety and meet the needs of different obese people.

[0035] Through the above animal model tests and human clinical trials, the weight loss effect and safety of this Chinese medicine weight loss formula have been fully verified, providing a strong basis for its clinical application. At the same time, personalized adjustments based on individual physique and health conditions can further improve the weight loss effect and safety and meet the needs of different obese people.

[0036] In the above description of this specification, unless otherwise clearly specified and limited, the terms "fixed", "installed", "connected" or "connected" should be understood in a broad sense. For example, with regard to the term "connection", it can be a fixed connection, a detachable connection, or an integral one; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be the internal connection of two elements or the interaction relationship between two elements. Therefore, unless otherwise clearly defined in this specification, those skilled in the art can understand the specific meanings of the above terms in the present invention according to the specific circumstances.

[0037] According to the above description of this specification, those skilled in the art may also understand the terms used below, such as "up", "down", "front", "back", "left", "right", "length", "width", "thickness", "vertical", "horizontal", "top", "bottom", "inside", "outside", "axial", "radial", "circumferential", "center", "longitudinal", "lateral", "clockwise" or "counterclockwise", etc., which indicate the orientation or position relationship. These terms are only for the purpose of facilitating the explanation of the scheme of the present invention and simplifying the description, rather than explicitly or implicitly indicating that the device or element involved must have the specific orientation, be constructed and operate in a specific orientation. Therefore, the above-mentioned orientation or position relationship terms cannot be understood or interpreted as limitations on the scheme of the present invention.

[0038] In addition, the terms "first" or "second" used in this specification to refer to numbers or ordinals are only used for descriptive purposes and cannot be understood as explicitly or implicitly indicating relative importance or implicitly indicating the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of this specification, the meaning of "plurality" is at least two, such as two, three or more, etc., unless otherwise clearly and specifically defined.

[0039] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A Chinese medicine weight loss formula, characterized in that: The formula includes the following raw materials: 8~15g of hawthorn; 6~12g of cassia seed; 6~12g of lotus leaf; 10~20g of Poria; 8~12g of Alisma; 5~12g of Atractylodes or tangerine peel; 1~5g of cinnamon; 1~15g of Ophiopogon japonicus; 1~12g of lily; 1~10g of Coptis chinensis; and 1~5g of processed Polygonum multiflorum.

2. The Chinese medicine weight loss formula according to claim 1, characterized in that: The formula includes the following raw materials: hawthorn 10~15g; cassia seed 6~8g; lotus leaf 6~12g; Poria 12~20g; Alisma orientalis 10~12g; Atractylodes macrocephala 10~12g; cinnamon bark 3~5g; Ophiopogon japonicus 1~2g; lily 1~2g; Coptis chinensis 1~10g; processed Polygonum multiflorum 1~5g.

3. The Chinese medicine weight loss formula according to claim 1, characterized in that: The formula includes the following raw materials: 8~10g of hawthorn; 6~12g of cassia seed; 6~12g of lotus leaf; 10~20g of Poria; 8~12g of Alisma; 8~12g of Atractylodes; 1~5g of cinnamon; 10~15g of Ophiopogon; 8~12g of lily; 1~10g of Coptis chinensis; and 1~5g of processed Polygonum multiflorum.