Food with effects of improving endurance and reducing weight and preparation method thereof

Abstract

The invention provides a food with the efficacy of improving endurance and reducing weight and a preparation method thereof. The food can be health-care food, beverage, milk tea and the like. The invention aims to solve the problems that in the prior art, a method for improving the endurance of people mainly adopts high-intensity training and nutritional supplement, so that the effect taking is slow, the individual difference is large, and the effect is not obvious. The invention relates to a food with the efficacy of improving endurance and reducing weight. The food comprises ketoglutaric acid and salidroside, the mass ratio of the ketoglutaric acid to the salidroside is 100: (3-6). Ketoglutaric acid and salidroside have a synergistic effect, so that the effects of improving energy metabolism, delaying fatigue and accelerating recovery can be achieved, the exercise tolerance can be enhanced, the body weight after taking can be maintained and even reduced, and the composition has a remarkable effect in the aspects of improving the tolerance and reducing the body weight.

Description

Technical Field

[0001] The invention belongs to the technical field of functional foods, and in particular relates to a food having the effects of improving endurance and reducing weight and a preparation method thereof. Background Art

[0002] In modern life, people are faced with various high-intensity physical and mental labor, which requires people to have higher and higher endurance. Therefore, people's demand for improving endurance, especially the ability to tolerate hypoxia, is also increasing.

[0003] Hypoxia refers to a pathological process in which tissues or cells in the body undergo abnormal changes in their morphological structure, physiological function, and metabolism due to insufficient oxygen supply or oxygen utilization disorders. The impact of hypoxia on the body's organs depends on the duration of hypoxia, the state of the body, and the degree of hypoxia. The body will have a compensatory response to hypoxia. In chronic mild hypoxia, the body's tissues mainly rely on increasing the ability to use oxygen and transport oxygen in the blood to adapt to chronic hypoxia, such as an increase in the number of red blood cells, the number of mitochondria in tissue cells, and the surface area of ​​the membrane. In acute hypoxia, the body's compensatory response is mainly based on the respiratory and circulatory systems, such as increased pulmonary ventilation and increased cardiac output. Clinically, hypoxia is the most common and most important factor causing various diseases and even death, so the problem of hypoxia has gradually received attention and attention.

[0004] The endurance requirements for high-intensity physical exercise may vary depending on individual lifestyle, career demands, health goals, and personal interests and hobbies. Here are some reasons why modern people may need to increase their endurance:

[0005] 1. Improved health awareness: With the improvement of health awareness, more and more people are starting to participate in sports to prevent diseases, improve physical fitness and enhance immunity.

[0006] 2. Weight loss and body shaping: Many people participate in high-intensity exercise to lose weight or shape their body. Endurance training helps burn more calories and achieve these goals.

[0007] 3. Competitive sports: Amateur and professional athletes need to improve their endurance and athletic performance through high-intensity training in order to achieve good results in competitions.

[0008] 4. Psychological stress release: High-intensity exercise can be used as a way to release stress, helping people relieve stress in work and life.

[0009] 5. Social activities: Group sports or fitness classes become new platforms for social interaction, where people build and maintain social relationships by participating in sports together.

[0010] 6. Improve work efficiency: Good physical fitness can improve work efficiency and the ability to handle daily activities, making people more energetic to cope with daily work.

[0011] 7. Elderly health: As they age, it is particularly important for older adults to maintain physical activity and endurance to prevent falls, maintain independent living, and slow cognitive decline.

[0012] In order to meet these needs, the traditional method of improving people's endurance is mainly through high-intensity training and nutritional supplements, but these methods often have certain limitations such as slow effect, large individual differences, and insignificant effects. Summary of the invention

[0013] The present invention provides a food with the effects of improving endurance and reducing weight and a preparation method thereof, aiming to solve the problem that the method for improving people's endurance in the prior art is mainly through high-intensity training and nutritional supplementation, which leads to slow effect, large individual differences and insignificant effect.

[0014] In order to solve the above technical problems, the technical solution adopted by the present invention is:

[0015] In a first aspect, the present invention provides a food having the effects of improving endurance and reducing weight, comprising ketoglutaric acid and salidroside; the mass ratio of the ketoglutaric acid to salidroside is 100:3-6.

[0016] A further solution: the mass ratio of ketoglutaric acid to salidroside is 100:3, 100:4 or 100:6.

[0017] Based on the above technical solution: the above ratio is a preferred ratio, which enables ketoglutaric acid and salidroside to achieve better synergistic effects, thereby enabling the beverage to better produce the effect of improving endurance.

[0018] A further solution: the food is a health food, milk tea or a beverage.

[0019] Based on the above technical solution: the food of the present invention is made into health food, milk tea or beverage, etc., which is conducive to the promotion of the food of the present invention.

[0020] A further solution: when the food is a beverage, the solute of the beverage includes ketoglutaric acid and salidroside; the concentration range of the solute of the beverage is 0.01-1%.

[0021] A further solution: the solvent of the beverage is water.

[0022] A further solution: the solute of the beverage further includes any one, two or three of a sweetener, a sour agent and a preservative.

[0023] Based on the above technical solution: by adding sweeteners and acidulants, the beverage has a good taste; by adding preservatives, the beverage has higher safety and extends the shelf life.

[0024] A further embodiment: when the solute of the beverage includes a sweetener, the sweetener is sucrose and / or high fructose corn syrup.

[0025] A further embodiment: when the solute of the beverage includes an acidulant, the acidulant is citric acid and / or malic acid.

[0026] A further embodiment: when the solute of the beverage includes a preservative, the preservative is potassium sorbate and / or sodium benzoate.

[0027] In a second aspect, the present invention provides a method for preparing a food having the effects of improving endurance and reducing weight, comprising:

[0028] S1. Dissolve salidroside and ketoglutaric acid in an appropriate amount of water and stir evenly;

[0029] S2. Add sweetener, acidulant and preservative, and stir until completely dissolved;

[0030] S3. Add purified water to the required volume and stir evenly;

[0031] S4, filtering and filling, and sterilizing to obtain the finished beverage;

[0032] The food comprises ketoglutaric acid and salidroside; the mass ratio of the ketoglutaric acid to salidroside is 100:3-6.

[0033] The beneficial effects of the present invention are:

[0034] The food of the present invention comprises ketoglutaric acid and salidroside. Firstly, the pharmacological effects of salidroside include anti-oxidation, anti-hypoxia, anti-fatigue, cardiovascular protection, anti-inflammatory, strong immunity and nerve protection. Ketoglutaric acid has the effects of improving energy metabolism, accelerating fat decomposition and consumption, and helping to reduce body weight, and can also play an important role in repairing muscle damage after exercise, can increase the levels of growth hormone and insulin, and inhibit muscle fiber decomposition.

[0035] The combined use of ketoglutaric acid and salidroside can produce a synergistic effect, which is mainly reflected in the following aspects:

[0036] 1. Enhanced energy metabolism: Ketoglutaric acid increases energy production, and salidroside improves oxygen utilization, and the two work together to enhance endurance;

[0037] 2. Anti-fatigue: Ketoglutaric acid can remove metabolic waste, and salidroside can reduce oxidative stress. The two work together to delay fatigue.

[0038] 3. Accelerated recovery: The anti-inflammatory and antioxidant effects of salidroside combined with the energy metabolism of ketoglutaric acid can promote recovery after exercise.

[0039] In summary, ketoglutaric acid and salidroside can enhance energy metabolism, delay fatigue and accelerate recovery through synergistic effects, thereby enhancing exercise endurance, and can maintain or even reduce body weight after taking it. This food has a significant effect in improving endurance and reducing weight. BRIEF DESCRIPTION OF THE DRAWINGS

[0040] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments are briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without paying creative work.

[0041] Figure 1 It is a schematic diagram of the swimming time of mice in the negative control group and each experimental group in the present invention.

[0042] Figure 2 It is a schematic diagram of the weight gain of mice in the negative control group and each experimental group in the present invention. DETAILED DESCRIPTION

[0043] The following will be combined with the accompanying drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative work belong to the protection scope of the present invention.

[0044] Embodiment 1:

[0045] This embodiment provides a food having the effects of improving endurance and reducing weight, comprising ketoglutaric acid and salidroside; the mass ratio of the ketoglutaric acid to salidroside is 100:3-6.

[0046] The mass ratio of ketoglutaric acid to salidroside can be 100:3, 100:4, 100:5 or 100:6, and the preferred ratios are 100:3 and 100:6.

[0047] Wherein, the food can be health food, milk tea or beverage and the like.

[0048] Wherein, when the food is a beverage, the solute of the beverage includes ketoglutaric acid and salidroside; the concentration range of the solute of the beverage is 0.01-1%.

[0049] In order to facilitate the preparation of the beverage and the drinking of the beverage, the solvent of the beverage is water.

[0050] In order to make the beverage taste better, sweeteners and / or acidulants may be added to the beverage.

[0051] The sweetener is sucrose and / or fructose syrup or the like.

[0052] The acidulant is citric acid and / or malic acid.

[0053] In order to make the beverage safer and extend the shelf life, a preservative may be added to the beverage. The preservative may be potassium sorbate and / or sodium benzoate.

[0054] Among them, salidroside has the following pharmacological effects:

[0055] 1. Anti-oxidation, anti-hypoxia and anti-fatigue

[0056] Salidroside has significant antioxidant capacity, can remove free radicals and protect cells from oxidative damage. Salidroside helps improve the body's adaptability to low oxygen environments and has a certain effect on alleviating altitude sickness. Salidroside has an anti-fatigue effect, can improve the body's work efficiency and mental activity, and enhance the response to light and electrical stimulation.

[0057] 2. Cardiovascular protection

[0058] Salidroside has a protective effect on the cardiovascular system, can reduce new fat production and cholesterol biosynthesis, and alleviate atherosclerosis in mice. Studies have shown that salidroside exerts cardiovascular protective effects by regulating blood lipid metabolism and reducing blood cholesterol and triglyceride levels. Salidroside helps improve heart health and reduce the risk of cardiovascular disease.

[0059] 3. Anti-inflammatory, immune-enhancing and neuroprotective

[0060] Salidroside has anti-inflammatory effects and can reduce inflammatory responses. Rhodiola rosea extract can regulate immune system function and enhance immunity. Salidroside has a protective effect on nerve cells and can reduce secondary nerve damage after traumatic brain injury. Its protective effect on the nervous system has been verified in many experiments by regulating the synthesis and release of neurotransmitters, improving nerve function, and relieving depression symptoms. Salidroside supports cognitive function, especially in cases of stress and fatigue.

[0061] Ketoglutaric acid has the following physiological functions:

[0062] 1. Energy metabolism

[0063] Ketoglutaric acid is an important intermediate product of the tricarboxylic acid cycle. It participates in cellular energy metabolism and provides energy for the body. It helps improve athletic ability and can also improve the body's oxygen utilization rate. It can be used as an ingredient in sports nutrition drinks to provide athletes and fitness enthusiasts with additional energy support to help them complete their training better. It can also improve athletic ability and performance.

[0064] 2. Amino Acid Synthesis and Muscle Health

[0065] Ketoglutaric acid is a precursor for the synthesis of various amino acids. It is of great significance to maintain the body's protein balance and promote growth and development. It is very important for muscle recovery and growth. It plays a key role in the biosynthetic pathway, providing raw materials for protein synthesis and promoting body growth. It has been proven to enhance muscle growth and is very suitable for sports and fitness people. It can increase lean body mass, promote muscle growth, and enhance muscle strength. It can promote metabolism, accelerate fat decomposition and consumption, and help lose weight.

[0066] 3. Regulation of nitrogen metabolism

[0067] Ketoglutaric acid participates in multiple cellular energy metabolism and multiple metabolic pathways, and has the function of regulating the body's energy metabolism. It can combine with excess ammonia in the body, reduce the problems caused by ammonia poisoning, and participate in the body's nitrogen metabolism process. It plays an important role in repairing muscle damage after exercise, increasing growth hormone and insulin levels, and inhibiting muscle fiber decomposition.

[0068] The food of the present invention has been experimentally verified to have a mass ratio of ketoglutaric acid to salidroside of preferably 100:3 or 100:6.

[0069] Embodiment 2:

[0070] The present invention provides a method for preparing a food having the effects of improving endurance and reducing weight, comprising:

[0071] S1. Dissolve salidroside and ketoglutaric acid in an appropriate amount of water and stir evenly;

[0072] S2. Add sweetener, acidulant and preservative, and stir until completely dissolved;

[0073] S3. Add purified water to the required volume and stir evenly;

[0074] S4, filtering and filling, and sterilizing to obtain the finished beverage;

[0075] The food comprises ketoglutaric acid and salidroside; the mass ratio of the ketoglutaric acid to salidroside is 100:3-6.

[0076] The present invention is further described below in conjunction with experiments:

[0077] 1. Experimental methods

[0078] 1. Dosage setting of ketoglutaric acid and salidroside:

[0079] 1) Currently, mature ketoglutaric acid supplements on the market are usually sold at a dose of 300 to 1000 mg, but the exact dose and time of taking are still recommended to be determined according to the product instructions; sports support products are more expensive than ordinary health products, and the maximum dose can even reach 15 to 18 g / day. It is recommended to take it in the early morning or about half an hour before or after exercise. It can be taken in multiple doses, on an empty stomach or with meals. Generally speaking, adults can take 500 mg to 1000 mg of ketoglutaric acid per day.

[0080] 2) Recommended dosage of salidroside in the Chinese Pharmacopoeia: According to the 2010 edition of the Chinese Pharmacopoeia, the recommended dosage of rhodiola rosea is 3 to 6 grams. Content of salidroside in health foods: In some specific health foods, such as Tongrentang brand rhodiola rosea capsules, each 100 grams contains 0.5 grams of salidroside. Another product, Beixing brand rhodiola rosea soft capsules, contains 580 mg of salidroside per 100 grams. There are also Jiahuitai brand rhodiola rosea capsules, which contain 1.26 grams of salidroside per 100 grams. Suggestions for use: When soaking rhodiola rosea in water, it is generally controlled within 15-30 grams. If used for physical health, it is recommended that the daily dosage should not exceed 10 grams.

[0081] Since the effect needs to be determined at the animal experiment level, the dosage conversion is as follows:

[0082] 3) Ketoglutaric acid: based on the human content of 0.5-1 gram / 60kg, the mouse dose is set in the range of 100-200 mg / kg.

[0083] 4) The daily dosage of Rhodiola rosea is about 30mg / person*60kg, which is 0.5mg / kg. The mouse dosage is 5.8mg / kg. The experimental range is 3-6mg / kg.

[0084] 2. Experimental animals: Healthy adult mice were selected and randomly divided into a negative control group and an experimental group.

[0085] Table 1 shows the negative control group given only saline and the experimental groups given different doses of salidroside and ketoglutaric acid

[0086]

[0087] 3. Administration method: As shown in Table 1, the mice in the experimental group were given salidroside and ketoglutaric acid every day, the dose of salidroside was 3 mg / kg, and the dose of ketoglutaric acid was different doses within the range of 100-200 mg / kg. Among them, experimental group 5 was given 100 mg / kg of ketoglutaric acid alone, experimental group 6 was given 200 mg / kg of ketoglutaric acid alone, and experimental group 7 was given 3 mg / kg of salidroside alone. The negative control group was given an equal amount of normal saline.

[0088] 4. Endurance test: The swimming test method was used to record the swimming time of mice. Animals were fed adaptively and randomly divided into groups according to body weight. Seven days after drug administration, mice were weighed 1 hour after drug administration, and paper clips were tied to the base of the tail according to their weight. Specifically, the paper clips were loaded with about 10% of their own body weight. Then the mice were put into the swimming box to swim, and the time from the start of swimming to the death of the mice was recorded as the swimming time of the mice.

[0089] 5. Other observation indicators: Measure the animal's weight at a fixed time every week and observe the animal's overall condition.

[0090] (II) Experimental Materials

[0091] 1. Salidroside: purity ≥98%;

[0092] 2. Ketoglutaric acid: purity ≥98%;

[0093] 3. Other reagents: All were of analytical grade.

[0094] (III) Experimental results and analysis

[0095] 1. Endurance test results and analysis: Figure 1 As shown, the swimming time of the negative control group given only saline was less than 200s. Compared with the negative control group, the swimming time of mice in multiple experimental groups was significantly prolonged, and the difference was statistically significant (P < 0.01). In the experimental group, the mice in the group given ketoglutaric acid and salidroside at the same time had a longer swimming time, especially the two groups with a mass ratio of ketoglutaric acid to salidroside of 100:3 and 100:6, the swimming time was close to 600s. The swimming time of mice given ketoglutaric acid or salidroside alone was shorter. It shows that the combination of ketoglutaric acid and salidroside can better improve the endurance of mice, especially the two groups with a mass ratio of ketoglutaric acid to salidroside of 100:3 and 100:6.

[0096] 2. Results and analysis of the effects of the two ingredients on the general condition and body weight of mice: After being given ketoglutaric acid and salidroside, the mice were in good general condition, moved freely, showed no drowsiness, no abnormal excitement, etc., had shiny and smooth fur, and no abnormal secretions. Figure 2As shown, the weight of mice in the negative control group increased significantly over time, while the weight gain of mice in the experimental group given different components alone or in combination was significantly reduced. The weight was significantly different from that of the negative control group at 8 days of administration, and this trend was maintained until 14 days. The results show that mice gained less weight after being given ketoglutaric acid or salidroside alone or both components at the same time.

[0097] (IV) Conclusion

[0098] The experimental results show that when the mass ratio of ketoglutaric acid and salidroside is 100:3 or 100:6, it can effectively improve the endurance of the user, and can maintain or even reduce the body weight after taking it, with no other observable adverse reactions.

[0099] The present invention is not limited to the above-mentioned optional implementation modes. Anyone can derive other various forms of products under the inspiration of the present invention. However, no matter what changes are made in the shape or structure, all technical solutions that fall within the scope defined by the claims of the present invention fall within the protection scope of the present invention.

Claims

1. A food having the effects of improving endurance and reducing weight, characterized in that: The invention comprises ketoglutaric acid and salidroside; the mass ratio of the ketoglutaric acid to salidroside is 100:3-6.

2. The food having the effects of improving endurance and reducing weight according to claim 1, characterized in that: The mass ratio of ketoglutaric acid to salidroside is 100:3, 100:4 or 100:

6.

3. The food having the effects of improving endurance and reducing weight according to claim 1, characterized in that: The food is health food, milk tea or beverage.

4. The food having the effects of improving endurance and reducing weight according to claim 3, characterized in that: When the food is a beverage, the solute of the beverage includes ketoglutaric acid and salidroside; the concentration of the solute of the beverage ranges from 0.01 to 1%.

5. The food having the effects of improving endurance and reducing weight according to claim 4, characterized in that: The solvent of the beverage is water.

6. The food having the effects of improving endurance and reducing weight according to claim 4, characterized in that: The solute of the beverage further comprises any one, two or three of a sweetener, a sour agent and a preservative.

7. The food having the effects of improving endurance and reducing weight according to claim 6, characterized in that: When the solute of the beverage includes a sweetener, the sweetener is sucrose and / or high fructose corn syrup.

8. The food having the effects of improving endurance and reducing weight according to claim 6, characterized in that: When the solute of the beverage includes an acidulant, the acidulant is citric acid and / or malic acid.

9. The food having the effects of improving endurance and reducing weight according to claim 6, characterized in that: When the solute of the beverage includes a preservative, the preservative is potassium sorbate and / or sodium benzoate.

10. A method for preparing a food having the effects of improving endurance and reducing weight, characterized in that: include: S1. Dissolve salidroside and ketoglutaric acid in an appropriate amount of water and stir evenly; S2. Add sweetener, acidulant and preservative, and stir until completely dissolved; S3. Add purified water to the required volume and stir evenly; S4, filtering and filling, and sterilizing to obtain the finished beverage; The food comprises ketoglutaric acid and salidroside; the mass ratio of the ketoglutaric acid to salidroside is 100:3-6.

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