Traditional Chinese medicine composition for treating amazing type insomnia and preparation method of traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition for treating insomnia prone to waking up. The traditional Chinese medicine composition is mainly prepared from the following medicinal materials: cassia twig, poria cocos, codonopsis pilosula, Chinese date, honey-fried licorice root, dried ginger, schisandra chinensis, radix paeoniae alba, ginger processed bamboo shavings, ginger processed pinellia, immature bitter orange, radix bupleuri, vinegar processed rhizoma cyperi, vinegar processed radix curcumae and pericarpium citri reticulatae viride. Research shows that the traditional Chinese medicine composition has the effects of soothing the nerves and helping sleep, can remarkably improve insomnia symptoms, and is relatively light in toxic and side effects and better in combined medication effect of traditional Chinese medicine and western medicine. Therefore, the composition disclosed by the invention is reasonable in formula and remarkable in curative effect, has potential application value in the aspect of preparing medicines for treating insomnia prone to waking up, and can be used as alternative treatment or auxiliary treatment of western medicines to enhance the curative effect of the western medicines, so that the symptoms such as insomnia and waking up due to waking up can be reduced or even replaced by the western medicines, and the toxic and side effects of the western medicines on human bodies are reduced.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating easy-awakening insomnia and a preparation method thereof. Background Art

[0002] With the increase of social, environmental and psychological pressures, the risk of mental illness in the population increases, and most patients suffer from insomnia. Common clinical manifestations of insomnia include difficulty falling asleep, shallow sleep, frequent dreams, easy awakening, early awakening, difficulty falling asleep after waking up, fatigue and tiredness after sleeping, daytime sleepiness, etc. In addition to the above symptoms, patients with anxiety insomnia may also feel anxious emotions such as irritability, persistent restlessness, nervousness, fear, night terrors and panic, or accompanied by autonomic nervous system symptoms such as dry mouth and flushed face, sweating, tension headaches, convulsions and tremors, and physical anxiety symptoms. Long-term anxiety can lead to depression, and depressive symptoms are often manifested as low mood, slow thinking, sleep disorders, physical symptoms, etc.

[0003] At present, the clinical treatment of insomnia mainly relies on Western medicine, and the side effects are obvious, usually manifested as drowsiness, dizziness, and exhaustion. Large doses are prone to ataxia, tremor, urinary retention, jaundice, and a few have rash, photosensitivity, leukopenia, excitement, polyphasia, sleep disorders, hallucinations, dry mouth, lack of concentration, sweating, palpitations, constipation or diarrhea, blurred vision, hypotension, etc. Ultimately, it aggravates the patient's depression and anxiety. In addition, Western medicine is mostly symptomatic treatment, and patients are prone to dependence, and patients cannot recover fundamentally.

[0004] Traditional Chinese medicine believes that insomnia belongs to the category of "insomnia". The Yellow Emperor's Classic of Internal Medicine once recorded insomnia as "cannot sleep", "cannot sleep", and "cannot lie down". Traditional Chinese medicine believes that insomnia is essentially a syndrome of deficiency and excess, which is closely related to dysfunction of the heart, liver, kidney, spleen and other organs, and mental malnutrition or restlessness. Since insomnia patients have a long course of disease, are prone to recurrent attacks, and are difficult to recover quickly, their treatment has always been one of the thorny problems faced by clinicians. In recent years, a large number of clinical practices have confirmed that traditional Chinese medicine has good clinical efficacy in the treatment of insomnia, and has unique advantages that Western medicine does not have, which can enable patients to obtain "twice the result with half the effort" clinical benefits. Therefore, traditional Chinese medicine treatment of insomnia, dreaminess, early awakening, anxiety, and depression has attracted great attention from medical workers. Summary of the invention

[0005] The technical problem to be solved by the present invention is to provide a Chinese medicine composition for treating easy-awakening insomnia with reasonable formula and significant curative effect and a preparation method thereof.

[0006] In order to solve the above technical problems, the present invention adopts the following technical solutions:

[0007] A traditional Chinese medicine composition for treating insomnia caused by easy awakening is mainly made of the following medicinal materials: cinnamon twig, poria, codonopsis pilosula, jujube, roasted licorice, dried ginger, schisandra chinensis, white peony root, ginger bamboo shavings, ginger pinellia, immature bitter orange, bupleurum, vinegar-soaked cyperus rotundus, vinegar-soaked curcuma, and green peel.

[0008] The above-mentioned Chinese medicine composition is mainly made of the following medicinal materials by weight: 10-15 parts of cinnamon twig, 10-15 parts of poria, 10-20 parts of codonopsis pilosula, 6-10 parts of jujube, 5-10 parts of roasted licorice, 10-15 parts of dried ginger, 10-15 parts of schisandra chinensis, 10-20 parts of white peony root, 10-20 parts of ginger bamboo shavings, 10-15 parts of ginger pinellia, 10-20 parts of bitter orange, 12-25 parts of bupleurum, 10-20 parts of vinegar cyperus rotundus, 10-20 parts of vinegar turmeric, and 10-20 parts of green peel.

[0009] The above-mentioned Chinese medicine composition is mainly made of the following medicinal materials by weight: 12 parts of cinnamon twig, 12 parts of Poria cocos, 12 parts of Codonopsis pilosula, 8 parts of jujube, 10 parts of roasted licorice, 12 parts of dried ginger, 12 parts of Schisandra chinensis, 15 parts of white peony root, 15 parts of ginger bamboo shavings, 12 parts of ginger pinellia, 15 parts of Citrus aurantium, 15 parts of bupleurum, 15 parts of vinegar Cyperus rotundus, 15 parts of vinegar Curcuma aromatica, and 12 parts of green peel.

[0010] Application of the above Chinese medicine composition in preparing medicine for treating insomnia caused by easy awakening.

[0011] A medicine for treating insomnia caused by easy awakening, comprising the above-mentioned Chinese medicine composition.

[0012] The above-mentioned medicine for treating insomnia of easy awakening type is an oral preparation.

[0013] Oral preparations are granules, decoctions, powders, capsules, tablets or oral solutions.

[0014] The preparation method of the above-mentioned medicine for treating insomnia caused by easy awakening,

[0015] Weigh the raw materials according to the formula, crush them and mix them; soak the crushed mixture in water; decoct after soaking; filter after decoction, concentrate the filtrate, and spray dry to obtain granules;

[0016] Alternatively, the raw materials are weighed and mixed according to the formula, the mixture is soaked in water, and then boiled after soaking, and the decoction is filtered out to obtain a decoction.

[0017] In the preparation method of granules, the soaking time is 2 hours; the decoction is performed twice, the first time the amount of water added is 12 times the weight of the mixed powder, and the decoction is performed for 1.5 hours, and the second time the amount of water added is 8 times the weight of the mixed powder, and the decoction is performed for 1 hour;

[0018] In the decoction preparation method, the soaking time is 2 hours; the decoction is performed twice, the first time the amount of water added is 8 times the weight of the mixed powder, and the decoction is performed for 1.5 hours, and the second time the amount of water added is 6 times the weight of the mixed powder, and the decoction is performed for 1 hour, and the decoctions are combined.

[0019] In view of the problem of easy awakening type insomnia, the inventor has developed a Chinese medicine composition for treating easy awakening type insomnia with Changzhong Anshen Pill as the base formula combined with clinical practice, which is mainly made of the following medicinal materials: cinnamon twig, Poria, Codonopsis pilosula, jujube, licorice root, dried ginger, Schisandra chinensis, white peony root, ginger bamboo shavings, ginger pinellia, immature bitter orange, bupleurum, vinegar cyperus, vinegar curcuma, green peel. Studies have shown that the present invention has the effect of calming the nerves and helping sleep, can significantly improve the symptoms of insomnia, and has relatively mild toxic and side effects, and the effect of combined Chinese and Western medicine is better. Therefore, the composition of the present invention has a reasonable prescription and significant efficacy, has potential application value in the preparation of drugs for treating easy awakening type insomnia, can be used as an alternative treatment for Western medicine, or as an auxiliary treatment to enhance the efficacy of Western medicine, thereby reducing or even replacing Western medicine to treat symptoms such as insomnia and easy awakening, thereby reducing the toxic and side effects of Western medicine on the human body. DETAILED DESCRIPTION

[0020] 1. Formula Principle and Analysis

[0021] The principle of insomnia treatment is to tonify deficiency and eliminate excess, adjust the yin and yang of the internal organs, and unblock the qi. If the internal organs are not harmonious, the qi will not rise and fall smoothly, and the emotions will be out of balance, which will lead to anxiety and insomnia. The spleen and stomach are the source of qi and blood production and the pivot of qi rise and fall. The "Four Sacred Heart Sources" says: Man and heaven and earth are in harmony; yin and yang are the foundation, and there is ancestral qi, which is the Tai Chi of man; within the ancestral qi, yin and yang are contained, and between yin and yang is the middle qi; the middle is earth, and the earth is divided into Wu and Ji. If the middle qi rotates to the left, it is Ji earth, and if the middle qi rotates to the right, it is Wu earth; Wu earth is the stomach, and Ji earth is the spleen.

[0022] The first reason for insomnia that is easy to wake up is the deficiency of heart and gallbladder qi. The heart governs the mind, and the gallbladder governs decision-making. When the positive qi is insufficient, the heart qi is weak, and the gallbladder qi is deficient, people tend to be timid and timid. In the sleeping state, the slightest movement will cause the mind to be uneasy, leading to easy awakening. Just like some people with weak constitution and timidity, they sleep very lightly and are easily awakened by external disturbances. The second reason is the disharmony between the heart and kidney. The kidney yin is insufficient, and it cannot help the heart fire, resulting in the heart fire being alone. Or the heart yang cannot warm the kidney, resulting in the imbalance of water and fire. In this state of imbalance between yin and yang, the mind cannot be stable, and it is easy to be disturbed and wake up during sleep. For example, people who stay up late for a long time or are overworked may experience this kind of disharmony between the heart and kidney. The third reason is liver depression and blood deficiency. If the liver is depressed, the qi will not flow smoothly. Qi is the leader of blood. If the qi is not smooth, the blood flow will be blocked, leading to blood deficiency. The liver stores blood, and if the blood is insufficient, the soul cannot be stored. The heart stores the spirit, and the spirit is uneasy, so it is easy to wake up at night. For example, people who have been in a bad mood for a long time have liver depression and blood deficiency, and they are easily awakened when sleeping. The fourth is disharmony between the spleen and stomach. The spleen and stomach are the source of Qi and blood production. If the spleen and stomach function is out of balance, on the one hand, they cannot normally transport the essence of water and grain to produce enough Qi and blood to nourish the mind; on the other hand, pathological products such as phlegm and dampness will be produced. These evil qi such as phlegm and dampness will disturb the mind, leading to unstable sleep and easy awakening. For example, people who eat too much before going to bed or have weak spleen and stomach are prone to waking up easily when sleeping.

[0023] This drug combination is based on Changzhong Anshen Pills, which can unclog the three jiaos, regulate emotions, and harmonize the yin and yang organs. Licorice and Poria nourish the earth and replenish the deficiency, while dried ginger is pungent and hot and dispersing. The three drugs are combined to strengthen the yang in the Kan and restore the meaning of the left rotation of the wheel axis. Cinnamon twig warms and unclogs the meridians. Cinnamon twig warms and disperses, and its nature is compatible with the liver, so the internal organs are smooth and the menstrual blood is smooth, so it is good at relieving spleen depression. Dry ginger and jujube are added to harmonize the spleen and stomach. Dry ginger and jujube can accelerate sleep, but jujube alone has no obvious effect. Licorice is used as a messenger to harmonize the drugs. Therefore, the ancestral qi is unblocked in the three jiaos, the power of the middle earth is restored, the growth of the liver is unblocked, blood stasis is not generated, the wood is unblocked, the soul is nourished by blood, and sleep is peaceful at night. Schisandra chinensis, licorice, and peony are combined, acid and sweet transform yin, so that the stomach yin can be nourished, then the earth moves and the lung metal descends. The combination of various drugs can make the power of the middle earth move the axis, the lung and stomach descend to the right, and the qi movement is restored. Codonopsis, Poria and Licorice can benefit the Qi of the heart and gallbladder. If the gallbladder fails to release, Qi stagnation will produce phlegm, and phlegm turbidity will disturb the body. If the gallbladder and stomach are not in harmony, the person will be timid and easily startled, restless and unable to sleep, have many strange dreams at night, and be anxious and uneasy. Pinellia is pungent and warm, can dry out dampness and resolve phlegm, harmonize the stomach and stop vomiting. It is supplemented with Rhizoma Anemarrhenae, which is sweet and slightly cold, can clear away heat and resolve phlegm, relieve restlessness and stop vomiting. Codonopsis, Poria and Licorice can benefit the Qi of the heart and gallbladder. Pinellia is combined with Rhizoma Anemarrhenae, one is warm and the other is cool, and can resolve phlegm and harmonize the stomach, stop vomiting and relieve restlessness; Citrus aurantium is pungent and warm, can regulate Qi and relieve stagnation, dry out dampness and resolve phlegm; Citrus aurantium is pungent and slightly cold, can descend Qi and remove stagnation, and eliminate phlegm and relieve abdominal distension. Citrus aurantium is combined with Citrus aurantium, which is also one warm and one cool, and the power of regulating Qi and resolving phlegm is increased. Therefore, cinnamon twig, bupleurum, cyperus rotundus, and green peel are used as the main ingredients to regulate the qi of the three burners, so that the qi of the internal organs can be regulated; the auxiliary ingredients are tangerine peel, curcuma, pinellia, schisandra, jujube, and codonopsis to relieve chest tightness and regulate qi, nourish the kidney and calm the mind, and coordinate the qi of the three burners; tuckahoe, white peony root, bamboo shavings, and dried ginger are used as the auxiliary ingredients to nourish yin, blood, calm the mind, and prolong sleep time. Roasted licorice is used to harmonize the various medicines.

[0024] in,

[0025] 1) Radix Licorice has the effects of tonifying spleen and stomach, replenishing qi and restoring pulse, relieving cough and asthma, and relieving pain. It is sweet in taste and flat in nature. It belongs to the heart meridian, lung meridian, stomach meridian and spleen meridian. It has the effects of invigorating spleen and replenishing qi, relieving cough and asthma, clearing away heat and detoxifying. It can treat symptoms such as spleen and stomach weakness, sinking of middle qi, qi deficiency and fatigue, and limb fatigue, thereby relieving insomnia symptoms. Radix Licorice can also reconcile the properties of drugs, enhance the efficacy of drugs, and relieve the toxicity and potency of drugs. It can also play a therapeutic effect for patients with some drug poisoning. In addition, Radix Licorice can also play a role in reconciling various drugs and play a soothing role in the prescription.

[0026] 2) Cinnamon twig, harmonizes the Ying and Wei, regulates the Ying and Wei patrols to reconcile Yin and Yang. It has the effects of sweating, relieving muscles, promoting Yang and transforming Qi, warming the meridians and dredges the blood vessels.

[0027] 3) Poria cocos, neutral in nature, sweet and light in taste. It enters the heart meridian, lung meridian, spleen meridian, and kidney meridian. It can promote diuresis and reduce swelling, strengthen the spleen and stop diarrhea, and calm the mind and tranquilize the nerves.

[0028] 4) Jujube, sweet, warm. Enters the spleen, stomach, and heart meridians. Functions and indications: tonifies the middle qi, nourishes blood and calms the mind. Used for spleen deficiency, loss of appetite, and fatigue.

[0029] 5) Codonopsis pilosula, sweet in taste, neutral in nature. It can nourish the middle qi, quench thirst, strengthen the spleen and lungs, nourish blood and produce body fluid. It is used for spleen and lung qi deficiency, poor appetite and fatigue, cough and asthma, qi and blood deficiency, sallow complexion, palpitations and shortness of breath, thirst due to loss of body fluid, and internal heat and thirst.

[0030] 6) Bupleurum, the medicinal part is the dried root of the Umbelliferae plant Bupleurum or Angustifolia, which is bitter and slightly cold in nature. It has the effects of reconciling the exterior and interior, soothing the liver and raising yang. It also has the effects of calming and prolonging sleep time. Experiments have shown that Bupleurum saponins can prolong the sleep time of cats, especially the increase of slow wave sleep stage II (SWS) and rapid eye movement sleep (REM) compared with before administration.

[0031] 7) Curcuma, which has the effects of promoting blood circulation and relieving pain, promoting qi and relieving depression, clearing the heart and cooling blood, and soothing the liver and promoting bile secretion. The turmeric dione in turmeric can significantly prolong sleep time, which shows that turmeric has the effect of inhibiting the central nervous system and achieving a calming effect.

[0032] 8) Schisandra chinensis has the effects of astringing, strengthening qi and promoting body fluid, nourishing the kidney and calming the mind.

[0033] 9) Pinellia ternata is pungent, warm and poisonous. It belongs to the lung, spleen and stomach meridians. It can treat insomnia and fight cancer. Its effect is often better than that of Ziziphus jujuba seed, Polygonum multiflorum, or Phellodendron chinense. Pinellia ternata is one of the shady slope plants. According to current research, shady slope plants can promote sleep.

[0034] 10) Dried ginger warms the middle and dispels cold, restores yang and unclogs the meridians, warms the lungs and eliminates phlegm. Modern research has found that dried ginger combined with jujube can accelerate sleep, while jujube alone has no obvious effect.

[0035] 11) Zhishi: bitter, pungent, slightly sour, slightly warm. Enters the spleen and stomach meridians. Helps digestion, relieves stagnation, resolves phlegm and relieves cough, regulates gastrointestinal smooth muscle, strengthens the heart and raises blood pressure.

[0036] 12) Qingpi, soothes the liver and relieves qi: Qingpi can soothe the liver and regulate qi, and has obvious therapeutic effects on symptoms such as chest and rib pain, breast pain, etc. caused by liver qi stagnation. Improves heart function: Qingpi has a cardiotonic effect, can enhance myocardial contractility, maintain normal heart rate levels, and has a positive effect on regulating heart function.

[0037] 13) Bamboo Shavings, which can clear away heat and relieve restlessness, can relieve depression, insomnia, suspicion, sighing and other symptoms. At the same time, it can also effectively stop nausea and vomiting caused by stomach heat, and is especially suitable for treating pregnancy vomiting. When used, it is often used in combination with tangerine peel, pinellia and other drugs to enhance the efficacy.

[0038] 14) White Peony Root is sour, bitter, slightly cold, and enters the liver and spleen meridians. Its main functions include nourishing blood and consolidating yin, softening the liver and relieving pain, and calming liver yang.

[0039] 15) Vinegar-flavored Cyperus rotundus, pungent, slightly bitter, slightly sweet, neutral, enters the liver meridian, spleen meridian, and triple burner meridian. Main functions: soothing the liver and relieving depression, regulating menstruation and relieving pain, calming the mind, antibacterial and anti-inflammatory, strengthening the heart and lowering blood pressure.

[0040] 2. Clinical Research and Results

[0041] 1Study medication

[0042] Recipe: 12 grams of cinnamon twig, 12 grams of Poria cocos, 12 grams of Codonopsis pilosula, 8 grams of jujube, 10 grams of roasted licorice, 12 grams of dried ginger, 12 grams of Schisandra chinensis, 15 grams of white peony root, 15 grams of Rhizoma Anemarrhenae, 12 grams of Pinellia ternata, 15 grams of Citrus aurantium, 15 grams of Bupleurum, 15 grams of vinegar Cyperus rotundus, 15 grams of vinegar Curcuma aromatica, and 12 grams of Citrus aurantium.

[0043] Preparation method: Weigh the raw materials according to the formula and mix them, soak the mixture in water for 2 hours; decoct after soaking, decoct twice, the first time add water amount of 8 times the weight of the mixture powder and decoct for 1.5 hours, the second time add water amount of 6 times the weight of the mixture powder and decoct for 1 hour; filter and combine the decoction to obtain a decoction (take twice in the morning and evening).

[0044] 2 Study design

[0045] The clinical study followed up 50 cases of insomnia with easy awakening, using a self-controlled before-and-after study. Among them, 10 cases were treated with pure Chinese medicine, 26 cases were treated with pure Western medicine, and 14 cases were treated with a combination of Chinese and Western medicine. The ages of the patients ranged from 14 to 90 years old.

[0046] Reference criteria for inclusion of cases of easy awakening insomnia: 1. Patients report that they are easily awakened during sleep and are easily frightened. 2. It takes more than 30 minutes to fall asleep; the total sleep time is less than 6 hours; 3. Feeling dizzy, listless, and weak when they wake up the next day; 4. The course of the disease lasts for 4 weeks to 6 months; 5. The PSQI scoring scale is used as a reference, and scores between 16 and 21 points are considered poor sleep.

[0047] Dosage: 1 dose of decoction per day, divided into 2 doses for warming. Observation index: PSQI was used to evaluate the therapeutic effect.

[0048] Clinical cure: clinical symptoms and signs of insomnia disappear or almost disappear, and the symptom score decreases by >95%; marked effect: clinical symptoms and signs of insomnia are significantly improved, and the symptom score decreases by 70%; effective: clinical symptoms and signs of insomnia are improved, and the symptom score decreases by 30%; ineffective: clinical symptoms and signs of insomnia are not significantly improved, or even aggravated, and the symptom score decreases by less than 30%. Note: The calculation formula (nimodipine method) is: [(score before treatment + score after treatment) / score before treatment]*100%

[0049] Pure Western medicine treatment was set as the control group, pure Chinese medicine treatment was set as treatment group 1, and combined Chinese and Western medicine treatment was set as treatment group 2.

[0050] In the control group, 70% of the patients took western medicine, mainly trazodone hydrochloride, alprazolam, etc., and the remaining 30% took clonazepam, sertraline, olanzapine, etc. The dosage was given according to the instructions depending on the specific situation of the patient.

[0051] 3 Research results (see Table 1)

[0052] Table 1 Clinical study results of the drug of the present invention

[0053]

[0054] Note: Total effective rate = cure rate + marked effective rate + effective rate.

[0055] Follow-up showed that some patients in the control group developed side effects such as hand tremors, dry mouth, nausea, hiccups, and drowsiness to varying degrees after treatment, while no obvious side effects were observed in the combined Chinese and Western medicine group and the pure Chinese medicine group.

[0056] It can be seen from the above content that the Chinese medicine composition provided by the present invention has the effect of calming the nerves and promoting sleep, can significantly improve the symptoms of insomnia, and has relatively mild toxic and side effects. The effect of combined use of Chinese and Western medicine is better.

Claims

1. A Chinese medicine composition for treating insomnia caused by easy awakening, characterized in that It is mainly made of the following medicinal materials: cinnamon twig, poria, codonopsis pilosula, jujube, roasted licorice, dried ginger, schisandra chinensis, white peony root, ginger bamboo shavings, ginger pinellia, bitter orange, bupleurum, vinegar cyperus, vinegar turmeric, and green peel.

2. The Chinese medicine composition according to claim 1, characterized in that The medicine is mainly prepared from the following medicinal materials by weight: 10-15 parts of cassia twig, 10-15 parts of poria, 10-20 parts of codonopsis pilosula, 6-10 parts of jujube, 5-10 parts of roasted liquorice, 10-15 parts of dried ginger, 10-15 parts of schisandra chinensis, 10-20 parts of white peony root, 10-20 parts of ginger bamboo shavings, 10-15 parts of ginger pinellia, 10-20 parts of immature bitter orange, 12-25 parts of bupleurum, 10-20 parts of vinegar cyperus rotundus, 10-20 parts of vinegar turmeric, and 10-20 parts of green peel.

3. The Chinese medicine composition according to claim 2, characterized in that The invention is mainly prepared from the following medicinal materials by weight: 12 parts of cinnamon twig, 12 parts of poria, 12 parts of codonopsis pilosula, 8 parts of jujube, 10 parts of roasted liquorice root, 12 parts of dried ginger, 12 parts of schisandra chinensis, 15 parts of white peony root, 15 parts of ginger bamboo shavings, 12 parts of ginger pinellia tuber, 15 parts of immature bitter orange, 15 parts of bupleurum, 15 parts of vinegar cyperus rotundus, 15 parts of vinegar turmeric, and 12 parts of green peel.

4. Use of the Chinese medicine composition according to any one of claims 1 to 3 in the preparation of a medicament for treating insomnia caused by easy awakening.

5. A drug for treating insomnia characterized by A Chinese medicine composition comprising any one of claims 1 to 3.

6. The drug for treating insomnia of easy awakening type according to claim 5, characterized in that It is an oral preparation.

7. The drug for treating insomnia of easy awakening type according to claim 6, characterized in that: The oral preparation is granules, decoctions, powders, capsules, tablets or oral liquids.

8. The method for preparing the drug for treating insomnia of easy awakening type according to claim 7, characterized in that: Weigh the raw materials according to the formula, crush them and mix them; soak the crushed mixture in water; decoct after soaking; filter after decoction, concentrate the filtrate, and spray dry to obtain granules; Alternatively, the raw materials are weighed and mixed according to the formula, the mixture is soaked in water, and then boiled after soaking, and the decoction is filtered out to obtain a decoction.

9. The preparation method according to claim 8, characterized in that: In the preparation method of granules, the soaking time is 2 hours; the decoction is performed twice, the first time the amount of water added is 12 times the weight of the mixture powder and the decoction is performed for 1.5 hours, and the second time the amount of water added is 8 times the weight of the mixture powder and the decoction is performed for 1 hour; in the preparation method of decoction, the soaking time is 2 hours; the decoction is performed twice, the first time the amount of water added is 8 times the weight of the mixture powder and the decoction is performed for 1.5 hours, and the second time the amount of water added is 6 times the weight of the mixture powder and the decoction is performed for 1 hour, and the decoctions are combined.

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