Centrifuge with Inner Wall Scraping Structure and Its Application in the Preparation of Bulk Drugs

Abstract

The present invention relates to the technical field of centrifuges, specifically a centrifuge with an inner wall scraping structure and its application in the preparation of bulk drugs. The centrifuge with an inner wall scraping structure includes a frame body and a centrifugal cylinder group arranged on the frame body. The centrifugal cylinder group includes a first cylinder fixedly installed on the frame body and a second cylinder arranged inside the first cylinder. A plurality of filter holes are arranged along the circumference of the second cylinder, and a gap is reserved between the inner wall of the first cylinder and the outer wall of the second cylinder. The second cylinder can rotate inside the first cylinder to perform centrifugal treatment on the materials in the second cylinder; it further includes a centrifugal driving mechanism installed on the frame body and capable of moving along the height direction of the frame body. The centrifugal mechanism can also close the upper end of the first cylinder and drive the second cylinder to rotate; through the cooperation of the ring body and the cutting knife, the cutting knife can pre-cut the crystals, making it smoother for the ring body to scrape the crystals, effectively reducing the load.

Description

Technical Field

[0001] The present invention relates to the technical field of centrifuges, and specifically to a centrifuge with an inner wall scraping structure and its application in the preparation of bulk drugs. Background Art

[0002] Centrifuges play a crucial role in the process of drug preparation. Through their unique physical principles and diverse functions, they efficiently process drugs, ensure drug quality, and promote the modernization and intelligent development of pharmaceutical production.

[0003] Bulk drugs are the starting materials in the drug production process, having a definite chemical structure, content, and purity, and are used in the manufacture of drug preparations. After the synthesis of bulk drugs, crystals and mother liquor are generally separated by a centrifuge. During the operation of the centrifuge, crystals often adhere to its inner wall due to temperature changes. To avoid waste of raw materials and affect subsequent use, it is generally necessary for staff to clean the inner wall of the centrifuge after the work is completed.

[0004] When cleaning the inner wall, it may be necessary for personnel to do it manually, which is too complicated. For this reason, some centrifuges are equipped with scraping mechanisms, usually with a scraper set on the inner wall. However, only by scraping the crystals with the scraper, it is necessary to ensure that the scraper has sufficient force to ensure the scraping effect. For this reason, the load of the scraping mechanism is relatively large, and the scraper is also easily worn and damaged, making it difficult to achieve the desired use effect. Summary of the Invention

[0005] The purpose of the present invention is to provide a centrifuge with an inner wall scraping structure and its application in the preparation of bulk drugs, so as to solve the problems raised in the above background art.

[0006] To achieve the above object, the present invention provides the following technical solution: A centrifuge with an inner wall scraping structure, including a frame body and a centrifuge tube group arranged on the frame body. The centrifuge tube group includes a first tube body fixedly installed on the frame body and a second tube body arranged inside the first tube body. A plurality of filter holes are arranged along the circumference of the second tube body, and a gap is reserved between the inner wall of the first tube body and the outer wall of the second tube body. The second tube body can rotate inside the first tube body to perform centrifugal treatment on the materials in the second tube body; it further includes: a centrifugal driving mechanism, installed on the frame body, capable of moving along the height direction of the frame body, and the centrifugal driving mechanism can also close the upper end of the first tube body and drive the second tube body to rotate; an inner wall scraping structure, including a plurality of cutting knives arranged equidistantly along the circumference in the second tube body and a ring body that is hermetically and slidably attached to the inner wall of the second tube body. The cutting knives are in contact with the inner wall of the second tube body, and the cutting knives and the ring body are connected to a rotation driving mechanism installed on the frame body. The rotation driving mechanism can drive the ring body to rotate and the cutting knives to perform circular motion; a height adjustment mechanism, arranged on the frame body, cooperating with the rotation driving mechanism, the height adjustment mechanism is intermittently triggered during the movement of the cutting knives and can cause the height of the cutting knives to change.

[0007] As a further solution of the present invention: The centrifugal driving mechanism includes a lifting plate member slidably arranged on the frame body and a sealing cover fixedly installed on the lifting plate member and adapted to the first tube body. A hydraulic cylinder is also installed on the frame body, and the movable end of the hydraulic cylinder is fixed to the lifting plate member; wherein, a feed inlet is arranged at the upper end of the second tube body, and the feed inlet cooperates with a power component installed on the sealing cover.

[0008] As a further solution of the present invention: The power component includes a first driving motor installed on the sealing cover and a plugging block fixed to the end of the output shaft of the first driving motor. The plugging block is square and adapted to the feed inlet.

[0009] As a further solution of the present invention: The rotation driving mechanism includes a rotating shaft rotatably installed on the frame body and a sleeve sleeved on the rotating shaft. The sleeve extends into the second tube body and is hermetically and rotatably connected to the first tube body and the second tube body; wherein, the sleeve is connected to the height adjustment mechanism, the ring body is fixed to the sleeve, and the cutting knives are connected to the sleeve through an elastic pressing component. The rotating shaft is also fixedly connected to a second gear, and the second gear meshes with a first gear rotatably installed on the frame body. A second driving motor with an output end connected to the rotating shaft of the first gear is installed on the frame body.

[0010] As a further solution of the present invention: two strip-shaped protruding portions are formed on the outer wall of the rotating shaft, and two strip-shaped grooves are provided on the inner wall of the sleeve. The strip-shaped grooves are adapted to the strip-shaped protruding portions, and both are parallel to the central axis of the rotating shaft and the sleeve.

[0011] As a further solution of the present invention: a plurality of saw teeth are equidistantly arranged along the circumference at the bottom of the ring body. The elastic pressing assembly includes an assembly cylinder fixed on the sleeve and a telescopic rod slidably sleeved on the assembly cylinder. One end of the telescopic rod is fixed to the cutting knife, and the other end is fixedly connected to a boss slidably arranged inside the assembly cylinder. A cylindrical spring is further arranged inside the assembly cylinder, and both ends of the cylindrical spring are respectively connected to the inner wall of the assembly cylinder and the boss.

[0012] As a further solution of the present invention: the height adjustment mechanism includes a threaded drive assembly installed on the frame body and an intermittent matching assembly connected to the threaded drive assembly. The threaded drive assembly is connected to the sleeve and can drive the sleeve to slide on the rotating shaft.

[0013] As a further solution of the present invention: the threaded drive assembly includes a lead screw rotatably installed on the frame body, a threaded sleeve sleeved on the lead screw and threadedly connected to the lead screw, and the threaded sleeve is fixedly connected with a follower plate member. The follower plate member is rotatably connected to the sleeve, and a guide groove adapted to the follower plate member is provided on the frame body.

[0014] As a further solution of the present invention: the intermittent matching assembly includes a third gear fixed on the lead screw, a cross arm fixed on the rotating shaft of the first gear, and an arc-shaped tooth plate fixed at one end of the cross arm far away from the rotating shaft of the first gear. The arc-shaped tooth plate cooperates with the third gear.

[0015] Application of the centrifuge with an inner wall scraping structure in the preparation of bulk drugs.

[0016] Compared with the prior art, the beneficial effects of the present invention are as follows: during the scraping process, the rotary drive mechanism can drive the ring body to rotate and the cutting knife to perform circular motion along the inner wall of the second cylinder. The cutting knife cuts the crystals on the inner wall. When the lifting and regulating mechanism is triggered, it can cause the cutting knife and the ring body to move downward. The cutting knife can then change the cutting route, and the rotating ring body can use the saw teeth to scrape off the crystals that have been cut by the cutting knife; therefore, through the coordinated action of the ring body and the cutting knife, the cutting knife can pre-cut the crystals, making the scraping of the crystals by the ring body smoother, effectively reducing the load and achieving the desired use effect. At the same time, the automatic adjustment of the positions of the cutting knife and the ring body enables the centrifuge to have an automatic inner wall scraping function, improving the efficiency of maintenance work and ensuring the effective operation of the centrifuge; in addition, when the hydraulic cylinder drives the lifting plate to drive the sealing cover to descend and close the upper end of the first cylinder, correspondingly, the blocking block is inserted into the feed port. On the one hand, the blocking block can block the feed port. On the other hand, when the first drive motor operates, since the blocking block is square, the blocking block can drive the second cylinder to rotate through the feed port, and the material located in the second cylinder can be centrifuged. The above two aspects reflect the diverse functions of the centrifuge.

[0017] In summary, the centrifuge with an inner wall scraping mechanism of the present invention can not only avoid waste and improve the yield, but also prevent the crystals adhering to the inner wall from affecting the purity of the crystals in the next batch of centrifugation. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 Isometric view of an embodiment of a centrifuge with an inner wall scraping structure;

[0019] Figure 2 Structural schematic diagram of an embodiment of a centrifuge with an inner wall scraping structure;

[0020] Figure 3 Structural schematic diagram of another angle of an embodiment of a centrifuge with an inner wall scraping structure;

[0021] Figure 4 Structural schematic diagram of yet another angle of an embodiment of a centrifuge with an inner wall scraping structure;

[0022] Figure 5 For Figure 4 Enlarged view of the structure at A in

[0023] Figure 6 Structural schematic diagram of the frame of an embodiment of a centrifuge with an inner wall scraping structure;

[0024] Figure 7 Internal structural schematic diagram of the first cylinder and the second cylinder of an embodiment of a centrifuge with an inner wall scraping structure;

[0025] Figure 8 For Figure 7 Schematic structural diagram from another perspective;

[0026] Figure 9 Schematic diagram showing the cooperation relationship between the rotary drive mechanism and the height adjustment mechanism in an embodiment of a centrifuge with an inner wall scraping structure;

[0027] Figure 10 Exploded view of the structure of the inner wall scraping structure in an embodiment of a centrifuge with an inner wall scraping structure.

[0028] In the figure: 1, frame body; 101, guide groove; 2, first cylinder; 3, assembly ring; 4, second cylinder; 401, feed port; 5, sealing cover; 6, first drive motor; 7, plugging block; 8, ring seat; 801, discharge hole; 9, lifting plate member; 10, hydraulic cylinder; 11, control valve; 12, second drive motor; 13, first gear; 14, cross arm; 15, arc-shaped toothed plate; 16, rotating shaft; 1601, strip-shaped convex portion; 17, sleeve; 1701, strip-shaped groove; 18, ring body; 1801, saw teeth; 19, assembly cylinder; 20, telescopic rod; 21, boss; 22, cutting knife; 23, cylindrical spring; 24, second gear; 25, third gear; 26, lead screw; 27, threaded sleeve; 28, follower plate member. Detailed implementation manners

[0029] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0030] In addition, an element in the present invention is referred to as being "fixed to" or "disposed on" another element, and it can be directly on the other element or there can also be an intermediate element. When an element is considered to be "connected" to another element, it can be directly connected to the other element or there may be an intermediate element at the same time. The terms "vertical", "horizontal", "left", "right" and similar expressions used herein are only for the purpose of illustration and do not represent the only implementation manners.

[0031] Please refer to Figures 1 - 10, in the embodiment of the present invention, a centrifuge with an inner wall scraping structure includes a frame body 1 and a set of centrifuge cylinders disposed on the frame body 1. The set of centrifuge cylinders includes a first cylinder body 2 fixedly installed on the frame body 1 and a second cylinder body 4 disposed inside the first cylinder body 2. A plurality of filter holes are provided along the circumference of the second cylinder body 4, and a gap is reserved between the inner wall of the first cylinder body 2 and the outer wall of the second cylinder body 4. The second cylinder body 4 can rotate inside the first cylinder body 2 to perform centrifugal treatment on the materials in the second cylinder body 4. It further includes: a centrifugal driving mechanism, installed on the frame body 1, capable of moving along the height direction of the frame body 1, and the centrifugal driving mechanism can also close the upper end of the first cylinder body 2 and drive the second cylinder body 4 to rotate; an inner wall scraping structure, including a plurality of cutting knives 22 equidistantly arranged along the circumference in the second cylinder body 4 and a ring body 18 that is hermetically and slidably attached to the inner wall of the second cylinder body 4. The cutting knives 22 are in contact with the inner wall of the second cylinder body 4, and the cutting knives 22 are connected to the ring body 18 and are connected to a rotation driving mechanism installed on the frame body 1. The rotation driving mechanism can drive the ring body 18 to rotate and the cutting knives 22 to perform circular motion; a height adjustment mechanism, disposed on the frame body 1, cooperating with the rotation driving mechanism, and the height adjustment mechanism is intermittently triggered during the movement of the cutting knives 22 and can cause the height of the cutting knives 22 to change.

[0032] It should be added that an assembly ring 3 is fixedly installed inside the first cylinder body 2, and the second cylinder body 4 is rotatably installed on the assembly ring 3. Secondly, a ring seat 8 is fixedly provided on the bottom wall of the first cylinder body 2. The ring seat 8 is hermetically and rotatably connected to the second cylinder body 4, and the lower surface of the ring seat 8 is flat. There is an included angle between the upper surface and the lower surface of the ring seat 8, and the lowest point of the upper surface is provided with a discharge hole 801 extending to the outside of the first cylinder body 2. A control valve 11 is installed at the discharge hole 801. During the centrifugal treatment process, the liquid-phase materials screened out through the filter holes on the second cylinder body 4 enter the gap between the first cylinder body 2 and the second cylinder body 4 and fall onto the upper surface of the ring seat 8, and then gather at the discharge hole 801. By opening the control valve 11, the materials can be discharged. Correspondingly, in order to facilitate the discharge of the materials remaining inside the second cylinder body 4, sealing doors are provided on both the first cylinder body 2 and the second cylinder body 4. After the work is completed, the sealing doors on both the first cylinder body 2 and the second cylinder body 4 are opened in sequence to clean the residual materials inside the second cylinder body 4.

[0033] Furthermore, after the centrifugation process ends and when it is necessary to process the crystals formed on the inner wall of the second cylinder 4, the rotation drive mechanism operates, driving the ring body 18 to rotate and the cutting knife 22 to perform a circular motion. Correspondingly, the cutting knife 22 can cut the crystals on the inner wall of the second cylinder 4. During this process, when the height adjustment mechanism is triggered, the height adjustment mechanism synchronously moves the cutting knife 22 and the ring body 18 downward. As a result, the cutting position of the cutting knife 22 on the crystals changes, and the ring body 18 can move downward while maintaining a rotating state to scrape the split crystals, achieving an effective inner wall scraping function and preventing the centrifugation effect from decreasing due to excessive crystals on the second cylinder 4. During the entire scraping process, the cutting knife 22 and the ring body 18 can gradually move axially along the second cylinder 4 inside the second cylinder 4, ensuring the comprehensiveness of the scraping process. Secondly, through the mutual cooperation of various mechanisms and the automatic adjustment of the positions of the cutting knife 22 and the ring body 18, the centrifuge is equipped with an automatic inner wall scraping function, improving the efficiency of maintenance work and providing guarantee for the effective operation of the centrifuge.

[0034] Please refer to again Figure 7 and Figure 8 , the centrifugal drive mechanism includes a lifting plate member 9 slidably disposed on the frame 1 and a sealing cover 5 fixedly installed on the lifting plate member 9 and adapted to the first cylinder 2. A hydraulic cylinder 10 is also installed on the frame 1, and the movable end of the hydraulic cylinder 10 is fixed to the lifting plate member 9. The upper end of the second cylinder 4 is provided with a feed inlet 401, and the feed inlet 401 cooperates with a power assembly installed on the sealing cover 5.

[0035] When it is necessary to convey the material to be centrifuged into the second cylinder 4, control the hydraulic cylinder 10 to drive the lifting plate member 9 to rise on the frame 1. Then, the lifting plate member 9 will drive the sealing cover 5 to separate from the first cylinder 2. Correspondingly, the feed inlet 401 is exposed, and the staff can convey the material to be centrifuged into the interior of the second cylinder 4 through the feed inlet 401. After the material conveyance is completed, the hydraulic cylinder 10 drives the lifting plate member 9 to drive the sealing cover 5 to descend, and the sealing cover 5 seals the upper end of the first cylinder 2 to create a reasonable centrifugation environment. To ensure the sealing effect between the sealing cover 5 and the first cylinder 2, a plurality of buckles (not shown in the figure) adapted to the sealing cover 5 are equidistantly arranged along the circumference on the first cylinder 2. After the descending process of the sealing cover 5 ends, the staff manually fastens the buckles to the sealing cover 5 to ensure the sealing effect.

[0036] The power assembly includes a first driving motor 6 mounted on the sealing cover 5 and a plugging block 7 fixed to the end of the output shaft of the first driving motor 6. The plugging block 7 is square and is adapted to the feed inlet 401.

[0037] The hydraulic cylinder 10 drives the lifting plate member 9 to drive the sealing cover 5 to descend. After closing the upper end of the first cylinder body 2, correspondingly, the plugging block 7 is inserted into the feed inlet 401. On the one hand, the plugging block 7 can plug the feed inlet 401. On the other hand, when the first driving motor 6 works, since the plugging block 7 is square, the plugging block 7 can drive the second cylinder body 4 to rotate through the feed inlet 401, and the materials in the second cylinder body 4 can be centrifuged.

[0038] Please refer to again Figure 2 、 Figure 8 、 Figure 9 and Figure 10 , the rotary driving mechanism includes a rotating shaft 16 rotatably installed on the frame body 1 and a sleeve 17 sleeved on the rotating shaft 16. The sleeve 17 extends into the second cylinder body 4 and is in sealed rotational connection with the first cylinder body 2 and the second cylinder body 4. Among them, the sleeve 17 is connected to the height adjusting mechanism, the ring body 18 is fixed to the sleeve 17, and the cutter 22 is connected to the sleeve 17 through an elastic pressing assembly. The rotating shaft 16 is also fixedly connected with a second gear 24, and the second gear 24 meshes with a first gear 13 rotatably installed on the frame body 1. A second driving motor 12 with an output end connected to the rotating shaft of the first gear 13 is installed on the frame body 1. Two strip-shaped protrusions 1601 are formed on the outer wall of the rotating shaft 16, and two strip-shaped grooves 1701 are provided on the inner wall of the sleeve 17. The strip-shaped grooves 1701 are adapted to the strip-shaped protrusions 1601, and both are parallel to the central axis of the rotating shaft 16 and the sleeve 17.

[0039] During work, the second driving motor 12 works to drive the first gear 13. The first gear 13 will drive the rotating shaft 16 through the second gear 24. Then, the rotating shaft 16 drives the sleeve 17 through the strip-shaped protrusions 1601 and the strip-shaped grooves 1701. The sleeve 17 drives the cutter 22 to move in a circular motion along the inner wall of the second cylinder body 4 through the elastic pressing assembly, so as to effectively cut the crystals on the second cylinder body 4, ensure the thoroughness of the subsequent scraping of the crystals, make the crystals easier to be scraped off by the ring body 18, and improve the effect of the inner wall scraping treatment.

[0040] A plurality of saw teeth 1801 are equidistantly arranged along the circumference at the bottom of the ring body 18. The elastic pressing component includes an assembly cylinder 19 fixed on the sleeve 17 and a telescopic rod 20 slidably sleeved with the assembly cylinder 19. One end of the telescopic rod 20 is fixed to the cutter 22, and the other end is fixedly connected to a boss 21 slidably arranged inside the assembly cylinder 19. A cylindrical spring 23 is further arranged inside the assembly cylinder 19, and two ends of the cylindrical spring 23 are respectively connected to the inner wall of the assembly cylinder 19 and the boss 21.

[0041] Wherein, the cylindrical spring 23 is in a compressed state. Therefore, under the elastic support of the cylindrical spring 23, it can ensure that the cutter 22 has sufficient pressure on the inner wall of the second cylinder body 4, so as to ensure that when the cutter 22 makes a circular motion, the crystals on the second cylinder body 4 can be effectively cut.

[0042] It should be emphasized that in order to prevent the cutter 22 from deflecting during the movement, a groove for sliding limit of the boss 21 should be arranged inside the assembly cylinder 19 to ensure that the boss 21 can only move along the axial direction of the assembly cylinder 19.

[0043] Please refer to again Figure 4 、 Figure 5 and Figure 9 , the height adjustment mechanism includes a threaded drive assembly installed on the frame body 1 and an intermittent matching assembly connected to the threaded drive assembly. The threaded drive assembly is connected to the sleeve 17 and can drive the sleeve 17 to slide on the rotating shaft 16.

[0044] The threaded drive assembly includes a lead screw 26 rotatably installed on the frame body 1, a threaded sleeve 27 sleeved on the lead screw 26 and threadedly connected to the lead screw 26. The threaded sleeve 27 is fixedly connected with a follower plate member 28. The follower plate member 28 is rotatably connected to the sleeve 17, and a guide groove 101 adapted to the follower plate member 28 is arranged on the frame body 1.

[0045] Specifically, the end of the follower plate member 28 extends into the guide groove 101 and is slidably connected to the frame body 1. The guide groove 101 is used to guide the movement of the follower plate member 28 and improve the stability of the threaded fit between the threaded sleeve 27 and the lead screw 26.

[0046] The intermittent matching assembly includes a third gear 25 fixed on the lead screw 26, a cross arm 14 fixed on the rotating shaft of the first gear 13, and an arc-shaped tooth plate 15 fixed at one end of the cross arm 14 away from the rotating shaft of the first gear 13. The arc-shaped tooth plate 15 is engaged with the third gear 25.

[0047] When the second drive motor 12 drives the first gear 13 to rotate, the cross arm 14 drives the arc-shaped toothed plate 15 to make a circular motion. When the teeth on the arc-shaped toothed plate 15 mesh with the third gear 25, the third gear 25 will drive the screw rod 26 to rotate. Therefore, the threaded sleeve 27 and the screw rod 26 are slidably matched, and the threaded sleeve 27 drives the follower plate 28 to move downward. Correspondingly, the follower plate 28 drives the sleeve 17 to slide downward on the rotating shaft 16, the height of the cutter 22 is reduced, and the ring body 18 is in the second cylinder 4. The ring body 18 keeps rotating and can scrape the crystals cut by the cutter 22 by using the saw teeth 1801; therefore, during the whole movement, the cutter 22 keeps circular motion, the ring body 18 keeps rotating, and the height of the cutter 22 and the ring body 18 is gradually reduced through the intermittent cooperation between the arc-shaped tooth plate 15 and the third gear 25, so as to realize the comprehensive cleaning of the crystals on the inner wall of the second cylinder 4, so that the centrifuge has an automatic inner wall cleaning function, improves the efficiency of maintenance work, and provides guarantee for the effective operation of the centrifuge.

[0048] In addition, in the specific implementation, after the scraping work is completed, the screw 26 needs to be rotated in the opposite direction so that the threaded sleeve 27 drives the cutter 22 and the ring body 18 to move up and reset through the follower plate 28 and the sleeve 17. For this purpose, the second drive motor 12 should use a servo motor with a bidirectional drive at the output end.

[0049] In addition, the circular motion of the cutter 22 includes forward circular rotation and reverse circular rotation. When the cutter 22 rotates in a forward circular motion, it performs a cutting action, and when it rotates in a reverse circular motion, it realizes an upward resetting action. By setting the blade of the cutter 22, the resetting action can be realized, and the cutter 22 will not cause damage to the inner wall of the second cylinder 4 when it rotates in a reverse circular motion.

[0050] As another embodiment of the present invention, the application of the centrifuge with the inner wall scraping structure in the preparation of raw materials is also proposed.

[0051] It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above and that the invention can be implemented in other specific forms without departing from the spirit or essential features of the invention. Therefore, the embodiments should be considered exemplary and non-limiting in all respects, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations falling within the meaning and scope of the equivalent elements of the claims be included in the invention. Any reference numeral in a claim should not be considered as limiting the claim to which it relates.

[0052] In addition, it should be understood that although this specification is described according to embodiments, not every embodiment only contains an independent technical solution. This narrative way of the specification is only for clarity. Those skilled in the art should regard the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A centrifuge with an inner wall scraping structure, comprising a frame and a set of centrifuge cylinders arranged on the frame. The set of centrifuge cylinders includes a first cylinder fixedly installed on the frame and a second cylinder arranged inside the first cylinder. A plurality of filter holes are provided along the circumference of the second cylinder, and a gap is reserved between the inner wall of the first cylinder and the outer wall of the second cylinder. The second cylinder can rotate inside the first cylinder to perform centrifugal treatment on the materials in the second cylinder; It is characterized in that It further includes: A centrifugal drive mechanism, installed on the frame, capable of moving along the height direction of the frame. The centrifugal drive mechanism can also close the upper end of the first cylinder and drive the second cylinder to rotate. The centrifugal drive mechanism includes a lifting plate member slidably arranged on the frame and a sealing cover fixedly installed on the lifting plate member and adapted to the first cylinder. A hydraulic cylinder is also installed on the frame, and the movable end of the hydraulic cylinder is fixed to the lifting plate member; A feed port is provided at the upper end of the second cylinder, and the feed port cooperates with a power assembly installed on the sealing cover. The power assembly includes a first drive motor installed on the sealing cover and a plugging block fixed to the end of the output shaft of the first drive motor; An inner wall scraping structure, including a plurality of cutting knives arranged equidistantly along the circumference in the second cylinder and a ring body in sealing sliding fit with the inner wall of the second cylinder. The cutting knives are in contact with the inner wall of the second cylinder, and the cutting knives are connected to the ring body by a rotary drive mechanism installed on the frame. The rotary drive mechanism can drive the ring body to rotate and the cutting knives to perform circular motion; The rotary drive mechanism includes a rotating shaft rotatably installed on the frame and a sleeve sleeved on the rotating shaft. The sleeve extends into the second cylinder and is in sealing rotary connection with the first cylinder and the second cylinder; A height adjustment mechanism, arranged on the frame, cooperating with the rotary drive mechanism. The height adjustment mechanism is intermittently triggered during the movement of the cutting knives and can cause the height of the cutting knives to change. The sleeve is connected to the height adjustment mechanism. The height adjustment mechanism includes a threaded drive assembly installed on the frame and an intermittent cooperation assembly connected to the threaded drive assembly. The threaded drive assembly is connected to the sleeve and can drive the sleeve to slide on the rotating shaft. The cutting knives are connected to the sleeve through an elastic pressing assembly. A plurality of saw teeth are arranged equidistantly along the circumference at the bottom of the ring body. The elastic pressing assembly includes an assembly cylinder fixed to the sleeve and a telescopic rod slidably sleeved on the assembly cylinder. One end of the telescopic rod is fixed to the cutting knife, and the other end is fixedly connected to a convex platform slidably arranged inside the assembly cylinder. A cylindrical spring is also arranged inside the assembly cylinder, and the two ends of the cylindrical spring are respectively connected to the inner wall of the assembly cylinder and the convex platform.

2. The centrifuge with an inner wall scraping structure according to claim 1, wherein, The plugging block is square and adapted to the feed port.

3. The centrifuge with an inner wall scraping structure according to claim 1, wherein, The ring body is fixed to the sleeve, and the rotating shaft is further fixedly connected with a second gear. The second gear meshes with a first gear rotatably mounted on the frame body, and a second driving motor with an output end connected to the rotating shaft of the first gear is mounted on the frame body.

4. The centrifuge with an inner wall scraping structure according to claim 3, characterized in that, Two strip-shaped protruding portions are formed on the outer wall of the rotating shaft, and two strip-shaped grooves are provided on the inner wall of the sleeve. The strip-shaped grooves are adapted to the strip-shaped protruding portions, and both are parallel to the central axis of the rotating shaft and the sleeve.

5. The centrifuge with an inner wall scraping structure according to claim 3, wherein, The threaded driving assembly includes a lead screw rotatably mounted on the frame body, a threaded sleeve sleeved on the lead screw and threadedly connected to the lead screw. The threaded sleeve is fixedly connected with a follower plate member. The follower plate member is rotatably connected to the sleeve, and a guiding groove adapted to the follower plate member is provided on the frame body.

6. The centrifuge with an inner wall scraping structure according to claim 5, characterized in that, The intermittent matching assembly includes a third gear fixed on the lead screw, a cross arm fixed on the rotating shaft of the first gear, and an arc-shaped tooth plate fixed at one end of the cross arm far away from the rotating shaft of the first gear. The arc-shaped tooth plate cooperates with the third gear.

7. Application of the centrifuge with an inner wall scraping structure according to any one of claims 1-6 in the preparation of bulk drugs.

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