3D printing skull based on PEEK material and repair and reconstruction system thereof

Abstract

The invention discloses a 3D printing skull based on a PEEK material and a repairing and reconstructing system of the 3D printing skull, and belongs to the technical field of skull repairing. The 3D printing skull based on the PEEK material comprises a skull body, the skull body comprises a strength assembly and a biological material assembly, and the biological material assembly is arranged on the outer side wall of the strength assembly; the strength assembly is a blank body, the biological material assembly is a biological material layer, all the outer side walls of the blank body are respectively provided with a biological material layer, and the biological material layers on the different side walls of the blank body are connected together in an integrated forming mode. The skull is prepared in a material combination mode, the manufacturing cost is reduced while it is ensured that the performance of the manufactured skull is ideal, and through efficient combination of the computer aided design technology and skull design and manufacturing, the skull is rapidly prepared, meanwhile, the manufacturing precision is extremely high, and the manufacturing cost is greatly reduced. Therefore, the skull with ideal performance is obtained under the condition that the skull cost is reduced.

Description

Technical Field

[0001] The present invention belongs to the technical field of skull repair, and in particular relates to a 3D printed skull based on PEEK material and a repair and reconstruction system thereof. Background Art

[0002] Skull defects caused by various reasons, such as craniocerebral trauma surgery or brain tumor surgery to remove the skull bone flap, due to the change in the shape of the skull defect area, the scalp is affected by atmospheric pressure, causing it to collapse and compress the brain tissue, seriously affecting brain function, and without the protection of the skull, the brain is very likely to be injured again. Therefore, skull repair surgery needs to be performed 3-6 months after the skull bone flap surgery.

[0003] At present, the commonly used skull repair materials can be divided into two categories: autologous bone and artificial materials. Among them, autologous bone is mainly used for autologous bone transplantation. Although autologous bone has good biocompatibility and no immune rejection reaction, it inevitably has the problem of limited sources; artificial materials include plexiglass, titanium plate, titanium mesh, bone cement, polymer fiber reinforced materials, etc. However, these artificial materials are not well combined in terms of biocompatibility, mechanical strength, and shape matching. For example, plexiglass has a certain tissue reaction, is brittle, and has poor impact resistance. The ideal skull repair implant material should have the following advantages: good individual matching, smooth appearance, and good fit with the skull; good biocompatibility, extremely low or no toxicity, no immunogenicity or low immunogenicity; good tissue compatibility, and the ability to allow bone cells to grow; it has the mechanical strength of real bone, enough to withstand intracranial pressure and possible impact from the outside world to protect the brain; it does not affect general imaging examinations such as CT and magnetic resonance imaging.

[0004] With the development of computer technology, computer-aided three-dimensional cranioplasty is increasingly being used in surgery. However, how to more efficiently combine computer-aided design technology with the design and production of skulls is still a widespread problem in this field. At the same time, PEEK material is the mainstream preparation material for artificial skulls today, but due to the high cost of PEEK material, the cost of artificial skulls is high, which limits the audience.

[0005] The information disclosed in this background technology section is only intended to enhance the understanding of the overall background of the invention and should not be regarded as an acknowledgment or any form of suggestion that the information constitutes the prior art already known to a person skilled in the art. Summary of the invention

[0006] The purpose of the present invention is to provide a 3D printed skull based on PEEK material and a repair and reconstruction system thereof, which can solve the problem of more efficient combination of computer-aided design technology for the design and production of the skull, and the problem of the high cost of the skull prepared by PEEK material resulting in a limited audience.

[0007] In order to achieve the above object, a technical solution provided by a specific embodiment of the present invention is as follows:

[0008] The 3D printed skull based on PEEK material includes a skull body, and the skull body includes a strength component and a biomaterial component, so that the skull body is synthesized by the strength component and the biomaterial component. The strength component can ensure that the prepared skull has sufficient strength to better protect the inside of the skull; the biomaterial component can ensure that when the artificial skull is repaired on the human head, the skull can be well fused with the human tissue, effectively avoiding the rejection between the skull and the human tissue, and improving the experience after the skull repair, so that the patient is comfortable. The biomaterial component is arranged on the outer wall of the strength component, so that the biomaterial component arranged on the outside of the strength component contacts the human tissue, and realizes an organic combination with the human tissue. The strength of the skull during use is ensured by the internal strength component. Specifically:

[0009] The strength component is the blank body. The strength component is the blank body, which greatly improves the processing efficiency of the strength component while meeting the use strength, so that the strength component can be quickly processed, thereby shortening the preparation time of the skull body and reducing the waiting time of the patient. The biomaterial component is a biomaterial layer. A biomaterial layer is provided on all the outer walls of the blank body. By providing the biomaterial layer on all the outer walls of the blank body, the blank body can be wrapped, thereby effectively avoiding the contact between human tissue and the blank body, preventing the components released by the blank body from contacting the human body, and avoiding rejection between human tissue. The biomaterial layers on different side walls of the blank body are connected together by integral molding, so that the biomaterial layer forms a whole to wrap the blank body.

[0010] In one or more embodiments of the present invention, the blank body is configured as a plate, and by bending the plate, it can be quickly made into a shape that matches the skull. The plate is made of titanium alloy material, which is suitable for the production of skulls. At the same time, the cost of titanium alloy material is low and can be quickly formed. The biomaterial layer is made of KEEP material, so that the biomaterial layer formed by the KEEP material contacts the human body, which greatly reduces the rejection between the skull and the human body after the skull repair.

[0011] In one or more embodiments of the present invention, the outer side wall of the blank body needs to be frosted, and the frosting adopts an irregular treatment method so that the outer side wall of the blank body is roughened by frosting. The biomaterial layer is arranged on the outer side wall of the blank body by 3D printing combined with laser cladding, so that the biomaterial layer is arranged on the outer side wall of the blank body by laser cladding and 3D printing, ensuring the mechanical strength of the connection between the blank body and the biomaterial layer. At the same time, due to the rough outer side wall of the blank body, the mechanical strength of the connection between the blank body and the biomaterial layer is better.

[0012] In one or more embodiments of the present invention, a plurality of first through holes are provided on the blank body, and the plurality of first through holes are provided with a plurality of shapes, including a circle and a polygon, and a biomaterial layer is provided on the outer wall of the blank body by 3D printing combined with laser cladding to provide a plurality of corresponding second through holes. The first through holes and the second through holes enable the human tissue to be better fused with the skull after the skull is installed. The first through holes and the second through holes are provided in a circle and a polygon to facilitate better fusion between the skull and the human body. At the same time, a biomaterial layer is provided on the side wall of the first through hole on the blank body for wrapping to ensure that the blank body does not contact the human tissue.

[0013] In one or more embodiments of the present invention, a plurality of mounting grooves are provided at the edge of the biomaterial layer, and screw holes are provided on the plurality of mounting grooves, and the screw holes penetrate the blank body, so that the skull can be fixed on the patient's head through the bone plate. The edges of the biomaterial layer are rounded to ensure better contact between the skull and the patient's head.

[0014] A 3D printed skull repair and reconstruction system based on PEEK material, the repair and reconstruction system comprising:

[0015] A three-dimensional modeling system, including an image acquisition component and a three-dimensional modeling component;

[0016] The manufacturing device body includes an operating table, on which is installed a device for processing the blank body, and the operating table is also installed with a device for arranging a biological material layer on the outer side wall of the blank body;

[0017] Control systems, including 3D modeling software and CAM systems.

[0018] In one or more embodiments of the present invention, the image acquisition component uses a CT device or a three-dimensional scanner to scan the patient's skull, and the three-dimensional modeling component uses the image acquired by the image acquisition component to obtain a three-dimensional image of the patient's skull defect through modeling.

[0019] In one or more embodiments of the present invention, a partition plate is fixedly connected to the operating table, and the partition plate divides the operating table into a blank processing area on the left and a biomaterial production area on the right. The equipment for processing the blank body is installed in the blank processing area, and the equipment for setting the biomaterial layer on the outer wall of the blank body is installed in the biomaterial production area. The equipment for processing the blank body includes a blank processing device, and the blank processing device is installed on the operating table. When the blank body is produced, since the blank body needs to be bent, polished and cut, the bending, polishing and cutting of the blank body are completed by the blank processing device. A first telescopic device is installed on the blank processing device, and a hole opening device is installed on the driving end of the first telescopic device. The first through hole on the blank body can be opened by driving the hole opening device to move through the first telescopic device. The equipment for setting the biomaterial layer on the outer side wall of the blank body includes a 3D printing and cladding integrated equipment. A second telescopic device is installed on the operating table. The 3D printing and cladding integrated equipment is installed on the driving end of the second telescopic device. The 3D printing and cladding integrated equipment is driven to move by the second telescopic device, so that the 3D printing and cladding integrated equipment can set the biomaterial layer on the outer side wall of the processed blank body by laser cladding and 3D printing.

[0020] In one or more embodiments of the present invention, the operating table is provided with a plurality of first waste discharge holes in the blank processing area, and a first waste collection box is installed at the bottom of the operating table below the plurality of first waste discharge holes. When the blank body is processed, the waste generated is collected in the first waste collection box through the first waste discharge holes so as to be recycled for secondary use. The operating table is provided with a plurality of second waste discharge holes in the biomaterial production area, and a second waste collection box is installed at the bottom of the operating table below the plurality of second waste discharge holes. When the biomaterial layer is printed, the waste generated is collected in the second waste collection box through the second waste discharge holes so as to be recycled for secondary use. A robotic arm is installed on the operating table, and the blank body can be moved and fixed by the robotic arm so as to complete processing in the blank processing area and the biomaterial processing area, thereby preparing the desired skull.

[0021] In one or more embodiments of the present invention, the 3D modeling software is connected to the three-dimensional modeling system by signals, the CAM system is connected to the three-dimensional modeling system by signals, and the CAM system is connected to the manufacturing equipment body by signals. The manufacturing equipment body is controlled by the CAM system so that when the blank processing equipment processes the blank body, the blank body is processed into a shape matching the skull according to the skull modeled by the three-dimensional modeling system, and the hole opening device is controlled to open holes in the blank body matching the skull shape. When the processing of the blank body is completed in the blank processing area, the 3D printing and cladding integrated equipment can be controlled to set a biomaterial layer on the outer surface of the blank body by laser cladding and 3D printing, thereby completing the processing of the skull.

[0022] Compared with the prior art, the present invention has the following advantages:

[0023] 1. The skull provided by the present invention is composed of an internal blank body and an external biological material layer, so that the materials used to prepare the skull are mostly titanium alloy materials and a small amount of KEEP materials, thereby reducing the amount of KEEP materials used in skull preparation. Since the cost of titanium alloy materials is relatively low, the cost of skull production is further reduced, so as to facilitate the promotion and use of skulls;

[0024] 2. The present invention obtains a three-dimensional image of the skull through modeling, controls the equipment in the manufacturing equipment body through the control system to process the blank body, so as to process the blank body into a shape matching the skull, and then uses the 3D printing equipment to set the KEEP material on the outside of the blank body through laser cladding and 3D printing, thereby completing the production of the skull;

[0025] 3. The present invention prepares the skull by combining materials, thereby ensuring that the skull has ideal performance while reducing the cost. In addition, by efficiently combining computer-aided design technology with skull design and production, the skull can be prepared quickly and with extremely high production accuracy, thereby obtaining a skull with ideal performance while reducing the cost of the skull. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0027] Figure 1 This is a schematic diagram of a 3D printed skull based on PEEK material in one embodiment of the present invention;

[0028] Figure 2A cross-sectional view of a 3D printed skull based on PEEK material in one embodiment of the present invention;

[0029] Figure 3 For the present invention Figure 2 Schematic diagram at A in the middle;

[0030] Figure 4 A schematic diagram of the blank body in the present invention;

[0031] Figure 5 A schematic diagram of a 3D printed skull repair and reconstruction system based on PEEK material in one embodiment of the present invention;

[0032] Figure 6 This is a stereoscopic diagram of a 3D printed skull repair and reconstruction system based on PEEK material in one embodiment of the present invention.

[0033] Description of main reference numerals:

[0034] 1-skull body, 11-blank body, 12-biomaterial layer, 13-first through hole, 14-second through hole, 15-mounting groove, 16-screw hole, 2-production equipment body, 21-operating table, 22-partition plate, 23-blank processing equipment, 24-first telescopic device, 25-hole opening device, 26-second telescopic device, 27-3D printing equipment, 28-first waste discharge hole, 29-first waste collection box, 210-second waste discharge hole, 211-second waste collection box, 212-robotic arm. DETAILED DESCRIPTION

[0035] In order to enable those skilled in the art to better understand the technical solutions in the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the present invention.

[0036] like Figure 1 and Figure 2 As shown, a 3D printed skull based on PEEK material in one embodiment of the present invention includes a skull body 1.

[0037] Specifically, the skull body 1 includes a strength component and a biomaterial component, so that the skull body 1 is synthesized by the strength component and the biomaterial component. The strength component can ensure that the prepared skull has sufficient strength to better protect the skull; the biomaterial component can ensure that when the artificial skull is repaired on the human head, the skull can be well fused with the human tissue, effectively avoiding the rejection between the skull and the human tissue, and improving the experience after the skull repair, so that the patient is comfortable. The biomaterial component is arranged on the outer wall of the strength component, so that the biomaterial component arranged on the outer side of the strength component contacts the human tissue, and realizes an organic combination with the human tissue, and the strength of the skull during use is ensured by the internal strength component.

[0038] like Figure 1 to Figure 3 As shown, the strength component is the blank body 11. The strength component is the blank body 11, which greatly improves the processing efficiency of the strength component while meeting the use strength, so that the strength component can be quickly processed, thereby shortening the preparation time of the skull body 1 and reducing the waiting time of the patient. The biomaterial component is a biomaterial layer 12. A layer of biomaterial layer 12 is provided on all the outer walls of the blank body 11. By providing the biomaterial layer 12 on all the outer walls of the blank body 11, the blank body 11 can be wrapped, thereby effectively avoiding the contact between human tissue and the blank body 11, preventing the components released by the blank body 11 from contacting the human body, and avoiding rejection between human tissue. The biomaterial layers 12 on different side walls of the blank body 11 are connected together by integral molding, so that the biomaterial layer 12 forms a whole to wrap the blank body 11.

[0039] Specifically, the blank body 11 is set as a plate, and by bending the plate, it can be quickly made into a shape that matches the skull. The plate is made of titanium alloy material, which is suitable for the production of the skull. At the same time, the cost of titanium alloy material is low and can be quickly formed. The biomaterial layer 12 is made of KEEP material, so that the biomaterial layer formed by the KEEP material contacts the human body, which greatly reduces the rejection between the skull and the human body after the repair.

[0040] Preferably, the blank body 11 can be quickly processed into a shape matching the skull by using a titanium alloy plate, and a biological material layer of KEEP material is arranged on the outside of the titanium alloy plate, so that an artificial skull can be manufactured by using the titanium alloy plate arranged inside and the KEEP material layer arranged outside, thereby greatly reducing the amount of KEEP material used and effectively reducing the cost of the artificial skull. At the same time, the rapid processing of the titanium alloy plate greatly shortens the preparation time of the artificial skull, thereby reducing the waiting time for the patient's surgery and reducing the cost of production, thereby further reducing the cost of the artificial skull. In addition, the KEEP material ensures that the skull has good biocompatibility, the titanium alloy plate ensures that the skull has good mechanical strength, and the KEEP material does not affect the imaging examination and has excellent thermal insulation performance, so that the prepared skull has ideal performance.

[0041] Furthermore, the outer wall of the blank body 11 needs to be frosted, and the frosting adopts an irregular processing method so that the outer wall of the blank body 11 is roughened by frosting. The biomaterial layer 12 is arranged on the outer wall of the blank body 11 by 3D printing combined with laser cladding, so that the biomaterial layer 12 is arranged on the outer wall of the blank body 11 by laser cladding and 3D printing, ensuring the mechanical strength of the blank body 11 and the biomaterial layer 12 after connection. At the same time, due to the rough outer wall of the blank body 11, the mechanical strength of the blank body 11 and the biomaterial layer 12 is better.

[0042] like Figure 1 to Figure 4 As shown, a plurality of first through holes 13 are provided on the blank body 11, and the plurality of first through holes 13 are provided with a plurality of shapes, including a circle and a polygon. The biomaterial layer 12 is provided on the outer wall of the blank body 11 by 3D printing combined with laser cladding, and a plurality of corresponding second through holes 14 are provided. The first through holes 13 and the second through holes 14 enable the human tissue to be better fused with the skull after the skull is installed. The first through holes 13 and the second through holes 14 are provided in a circle and a polygon, so as to facilitate a better fusion between the skull and the human body. At the same time, the side wall of the first through hole 13 on the blank body 11 is provided with a biomaterial layer 12 for wrapping to ensure that the blank body 11 does not contact the human tissue.

[0043] like Figure 1 to Figure 4 As shown, a plurality of mounting grooves 15 are provided at the edge of the biomaterial layer 12, and screw holes 16 are provided on the plurality of mounting grooves 15. The screw holes 16 penetrate the blank body 11, and the skull can be fixed on the patient's head through the bone plate through the mounting grooves 15 and the screw holes 16. The edges of the biomaterial layer 12 are rounded to ensure better contact between the skull and the patient's head.

[0044] A 3D printed skull repair and reconstruction system based on PEEK material, the repair and reconstruction system includes a three-dimensional modeling system, a manufacturing device body 2 and a control system.

[0045] Specifically, the three-dimensional modeling system includes an image acquisition component and a three-dimensional modeling component; the image acquisition component uses a CT device or a three-dimensional scanner to scan the patient's skull, and the three-dimensional modeling component uses the image acquired by the image acquisition component to obtain a three-dimensional image of the patient's skull defect through modeling.

[0046] like Figure 5 and Figure 6 As shown, the manufacturing equipment body 2 includes an operating table 21 , on which equipment for processing the blank body 11 is installed. At the same time, the operating table 21 is also equipped with equipment for setting the biomaterial layer 12 on the outer side wall of the blank body 11 .

[0047] like Figure 5 and Figure 6 As shown, a partition plate 22 is fixedly connected to the operating table 21, and the partition plate 22 divides the operating table 21 into a blank processing area on the left and a biomaterial production area on the right. The equipment for processing the blank body 11 is installed in the blank processing area, and the equipment for setting the biomaterial layer 12 on the outer wall of the blank body 11 is installed in the biomaterial production area. The equipment for processing the blank body 11 includes a blank processing device 23, which is installed on the operating table 21. When the blank body 11 is produced, since the blank body 11 needs to be bent, polished and cut, the blank body 11 is bent, polished and cut by the blank processing device 23. A first telescopic device 24 is installed on the blank processing device 23, and a hole opening device 25 is installed at the driving end of the first telescopic device 24. The first through hole 13 on the blank body 11 can be opened by driving the hole opening device 25 to move through the first telescopic device 24. The equipment used to set the biomaterial layer 12 on the outer wall of the blank body 11 includes a 3D printing and cladding integrated equipment 27. A second telescopic device 26 is installed on the operating table 21. The 3D printing and cladding integrated equipment 27 is installed at the driving end of the second telescopic device 26. The 3D printing and cladding integrated equipment 27 is driven to move by the second telescopic device 26, so that the 3D printing and cladding integrated equipment 27 can set the biomaterial layer 12 on the outer wall of the processed blank body 11 by laser cladding and 3D printing.

[0048] like Figure 5 and Figure 6As shown, the operating table 21 is provided with a plurality of first waste discharge holes 28 in the blank processing area, and a first waste collection box 29 is installed at the bottom of the operating table 21 below the plurality of first waste discharge holes 28. When the blank body 11 is processed, the waste generated is collected in the first waste collection box 29 through the first waste discharge holes 28 so as to be recycled for secondary use. The operating table 21 is provided with a plurality of second waste discharge holes 210 in the biomaterial production area, and a second waste collection box 211 is installed at the bottom of the operating table 21 below the plurality of second waste discharge holes 210. When the biomaterial layer 12 is printed, the waste generated is collected in the second waste collection box 211 through the second waste discharge holes 210 so as to be recycled for secondary use. A mechanical arm 212 is installed on the operating table 21, and the blank body 11 can be moved and fixed by the mechanical arm 212 so as to complete the processing in the blank processing area and the biomaterial processing area, thereby preparing the desired skull.

[0049] The control system includes 3D modeling software and CAM system.

[0050] Specifically, the 3D modeling software is connected to the three-dimensional modeling system by signals, the CAM system is connected to the three-dimensional modeling system by signals, and the CAM system is connected to the manufacturing equipment body 2 by signals. The manufacturing equipment body 2 is controlled by the CAM system so that when the blank processing device 23 processes the blank body 11, the blank body 11 is processed into a shape matching the skull according to the skull modeled by the three-dimensional modeling system, and the hole opening device 25 is controlled to open holes in the blank body 11 matching the skull shape. When the processing of the blank body 11 is completed in the blank processing area, the 3D printing and cladding integrated device 27 can be controlled to set the biomaterial layer 12 on the outer surface of the blank body 11 by laser cladding and 3D printing, thereby completing the processing of the skull.

[0051] When in use, the image acquisition component is first used to acquire images of the patient's head part so as to obtain images of the missing part of the patient's skull. Then, the 3D modeling component obtains a 3D image of the patient's skull through the image acquisition component, thereby modeling the size and shape of the skull required for the patient's skull defect. When the 3D modeling system obtains the 3D image of the skull required by the patient, the CAM system obtains the 3D image of the skull, and the CAM system controls the blank processing device 23 to bend, cut and grind the blank body 11 so as to make the blank body 11 into a desired shape. It is made into a shape matching the required skull, and then the CAM system controls the hole-opening device 25 to complete the hole-opening of the blank body 11, so as to complete the processing of the blank body 11; then the blank body 11 is moved to the biomaterial production area by the robot arm 212, and the 3D printing and cladding integrated equipment 27 is controlled by the CAM system. The 3D printing and cladding integrated equipment 27 will set the biomaterial layer 12 on the outer surface of the blank body 11 by laser cladding and 3D printing, so that the required skull can be obtained by the combination of the blank body 11 and the biomaterial layer 12.

[0052] It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above and that the invention can be implemented in other specific forms without departing from the spirit or essential features of the invention. Therefore, the embodiments should be considered exemplary and non-limiting in all respects, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations falling within the meaning and scope of the equivalent elements of the claims be included in the invention. Any reference numeral in a claim should not be considered as limiting the claim to which it relates.

[0053] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A 3D printed skull based on PEEK material, including a skull body, characterized in that: The skull body comprises a strength component and a biomaterial component, wherein the biomaterial component is arranged on the outer side wall of the strength component. Specifically: The strength component is the blank body, the biomaterial component is the biomaterial layer, a biomaterial layer is arranged on all outer side walls of the blank body, and the biomaterial layers on different side walls of the blank body are connected together by integral molding.

2. The 3D printed skull based on PEEK material according to claim 1, characterized in that: The blank body is configured as a plate, the plate is made of a titanium alloy material, and the biomaterial layer is made of a KEEP material.

3. The 3D printed skull based on PEEK material according to claim 2, characterized in that: The outer side wall of the blank body needs to be frosted in an irregular manner, and the biomaterial layer is arranged on the outer side wall of the blank body by a combination of 3D printing and laser cladding.

4. The 3D printed skull based on PEEK material according to claim 3, characterized in that: The blank body is provided with a plurality of first through holes, and the plurality of first through holes are arranged in a plurality of shapes, including a circle and a polygon. The biomaterial layer is arranged on the outer wall of the blank body by 3D printing combined with laser cladding to arrange a plurality of corresponding second through holes.

5. The 3D printed skull based on PEEK material according to claim 1, characterized in that: A plurality of mounting grooves are provided at the edge of the biomaterial layer, and screw holes are provided on the plurality of mounting grooves. The screw holes penetrate through the blank body, and the edge of the biomaterial layer is rounded.

6. The PEEK-based 3D printed skull repair and reconstruction system according to any one of claims 1 to 5, characterized in that: The repair and reconstruction system comprises: A three-dimensional modeling system, including an image acquisition component and a three-dimensional modeling component; The manufacturing device body includes an operating table, on which is installed a device for processing the blank body, and the operating table is also installed with a device for arranging a biological material layer on the outer side wall of the blank body; Control systems, including 3D modeling software and CAM systems.

7. The PEEK-based 3D printed skull repair and reconstruction system according to claim 6, characterized in that: The image acquisition component uses a CT device or a three-dimensional scanner to scan the patient's skull, and the three-dimensional modeling component uses the images obtained by the image acquisition component to obtain a three-dimensional image of the patient's skull defect through modeling.

8. The PEEK-based 3D printed skull repair and reconstruction system according to claim 6, characterized in that: A partition plate is fixedly connected to the operating table, and the partition plate divides the operating table into a blank processing area on the left and a biomaterial production area on the right. The equipment for processing the blank body is installed in the blank processing area, and the equipment for setting the biomaterial layer on the outer side wall of the blank body is installed in the biomaterial production area. The equipment for processing the blank body includes a blank processing equipment, and the blank processing equipment is installed on the operating table. A first telescopic device is installed on the blank processing equipment, and a hole opening device is installed on the driving end of the first telescopic device. The equipment for setting the biomaterial layer on the outer side wall of the blank body includes a 3D printing and cladding integrated equipment. A second telescopic device is installed on the operating table, and the 3D printing and cladding integrated equipment is installed on the driving end of the second telescopic device.

9. The PEEK-based 3D printed skull repair and reconstruction system according to claim 8, characterized in that: The operating table is provided with a plurality of first waste discharge holes in the blank processing area, a first waste collection box is installed at the bottom of the operating table below the plurality of first waste discharge holes, the operating table is provided with a plurality of second waste discharge holes in the biomaterial production area, a second waste collection box is installed at the bottom of the operating table below the plurality of second waste discharge holes, and a robotic arm is installed on the operating table.

10. The PEEK-based 3D printed skull repair and reconstruction system according to claim 6, characterized in that: The 3D modeling software is connected by signals to the three-dimensional modeling system, the CAM system is connected by signals to the three-dimensional modeling system, and the CAM system is connected by signals to the manufacturing equipment body.

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