High-efficiency stain-removing and tooth-protecting toothpaste for tea stains and preparation method thereof

Abstract

The invention discloses an efficient stain-removing and tooth-protecting toothpaste for tea stains and a preparation method of the toothpaste, and relates to the technical field of toothpaste. The cleansing cream is prepared from the following components in parts by weight: 30-38 parts of a friction agent, 1-2 parts of a surfactant, 3.5-6 parts of a stain-removing active component, 0.4-1 part of an enzyme component, 4.31-5.55 parts of a protective component, 0.5-1 part of an antioxidant component, 0.5-1 part of a natural extract, 35-45 parts of a wetting agent and 0.2-0.5 part of a refreshing component. The stain-removing active ingredients are sodium pyrophosphate, sodium citrate and polyaspartic acid. Through the synergistic effect of the stain-removing active components and the enzyme components, efficient removal of tea stains is realized. Sodium pyrophosphate is chelated with metal ions in tea stains, sodium citrate provides a weak acid environment to assist pigment decomposition, and papain and esterase further decompose protein compounds covering the tea stains, so that deep pigments are easier to fall off. The problem that traditional toothpaste cannot thoroughly clean tea stains is solved through the combined action of multiple components, and the stain removal efficiency is remarkably improved.

Description

Technical Field

[0001] The invention relates to the technical field of oral care, in particular to a toothpaste for efficiently removing tea stains and protecting teeth and a preparation method thereof. Background Art

[0002] Tea culture has a profound historical background and wide influence around the world, and tea drinking has become an indispensable part of many people's daily lives. However, in the process of long-term tea drinking, specific ingredients in tea beverages can have potential adverse effects on dental health. Tea beverages are rich in polyphenols, such as catechins, tannins, and thearubigins. These ingredients, after combining with proteins in saliva and metal ions in the mouth (such as calcium, iron, etc.), easily form dark stains on the surface of teeth, namely tea stains. Tea stains not only affect the beauty of teeth, causing difficult-to-remove yellow-brown spots on the surface of teeth, but also significantly increase the roughness of the tooth surface, thereby creating conditions for the attachment of other pollutants and the growth of bacteria, aggravating oral health problems.

[0003] The formation of tea stains has certain particularities. The core mechanism is that tea polyphenols combine with salivary proteins to form stable complexes. At the same time, these complexes easily react with calcified components on the surface of teeth, making pigment deposition more solid. In addition, because these components in tea beverages have certain lipophilicity, they can penetrate into the micropores and cracks of tooth enamel, resulting in a wider range of pigment deposition. These characteristics determine the stubbornness of tea stains. Traditional physical cleaning methods alone cannot effectively remove deep tea stains. At the same time, they may also cause damage to tooth enamel, further worsening the health of teeth.

[0004] Most toothpaste products on the market today can only perform preliminary cleaning on the surface tea stains, but lack effective solutions for deep tea stains and their complex formation mechanisms. Traditional toothpastes usually use high-hardness abrasives (such as silica) for physical cleaning. This method may cause a certain degree of wear on the tooth enamel while removing the pigment on the surface of the tea stains. Long-term use may lead to problems such as tooth sensitivity. In addition, although some toothpaste products have introduced chemical cleaning ingredients, their effectiveness is limited and it is difficult to decompose stable tea stain complexes, especially in the removal of deep tea stains. At the same time, existing products generally lack the function of protecting tooth enamel and inhibiting the re-attachment of tea stains, which makes it difficult to completely solve the problem of tea stains among tea drinkers. Summary of the invention

[0005] In view of the above and / or existing problems in the existing toothpaste for efficiently removing tea stains and protecting teeth, the present invention is proposed.

[0006] Therefore, the problem to be solved by the present invention is how to provide a toothpaste for effectively removing tea stains and protecting teeth and a preparation method thereof.

[0007] In order to solve the above technical problems, the present invention provides the following technical solutions: a highly effective tea stain removal toothpaste, comprising, by weight, 30-38 parts of abrasives, 1-2 parts of surfactants, 3.5-6 parts of active stain removal ingredients, 0.4-1 parts of enzyme ingredients, 4.31-5.55 parts of protective ingredients, 0.5-1 parts of antioxidant ingredients, 0.5-1 parts of natural extracts, 35-45 parts of wetting agents, and 0.2-0.5 parts of fresh ingredients;

[0008] The active stain removing ingredients are sodium pyrophosphate, sodium citrate and polyaspartic acid.

[0009] As a preferred embodiment of the highly effective tea stain removing toothpaste of the present invention, the mass ratio of the sodium pyrophosphate, sodium citrate and polyaspartic acid is 2-3:1-2:0.5-1.

[0010] As a preferred embodiment of the highly effective tea stain removing toothpaste of the present invention, the enzyme components are papain and esterase, wherein the mass ratio of papain to esterase is 0.2-0.5:0.2-0.5.

[0011] As a preferred embodiment of the toothpaste for efficiently removing tea stains according to the present invention, the abrasive is microcrystalline silicon dioxide and aluminum hydroxide, wherein the mass ratio of microcrystalline silicon dioxide to aluminum hydroxide is 25-30:5-8.

[0012] As a preferred embodiment of the toothpaste for efficiently removing tea stains according to the present invention, the abrasive is microcrystalline silicon dioxide and aluminum hydroxide, wherein the mass ratio of microcrystalline silicon dioxide to aluminum hydroxide is 25-30:5-8.

[0013] As a preferred embodiment of the highly effective tea stain removing toothpaste of the present invention, the mass ratio of the sodium pyrophosphate, sodium citrate and polyaspartic acid is 2.5:1:0.8.

[0014] As a preferred embodiment of the toothpaste for efficiently removing tea stains described in the present invention, the protective ingredients are nano-hydroxyapatite, strontium chloride and graphene oxide, wherein the mass ratio of nano-hydroxyapatite, strontium chloride and graphene oxide is 4-5:0.3-0.5:0.01-0.05.

[0015] As a preferred embodiment of the highly effective tea stain removing toothpaste of the present invention, the antioxidant component is L-ascorbic acid, and the surfactant is sodium lauroyl glutamate.

[0016] As a preferred embodiment of the highly effective tea stain removing toothpaste of the present invention, the natural extract is citrus extract.

[0017] As a preferred embodiment of the highly effective tea stain removing toothpaste of the present invention, the wetting agent is glycerol and water, wherein the mass ratio of glycerol to water is 20-25:15-20.

[0018] Another object of the present invention is to provide a method for preparing a toothpaste that is efficient in removing tea stains and protecting teeth.

[0019] A method for preparing a highly effective tea stain removing toothpaste, comprising the following steps: Step 1: adding an appropriate amount of glycerin and deionized water into a stirred reactor, stirring evenly, maintaining the temperature at 30-40° C., dissolving the glycerin completely to form a transparent base liquid, then slowly adding sodium lauroyl glutamate, continuing to stir until it is completely dissolved to form a stable liquid phase system;

[0020] Step 2: Add polyaspartic acid, sodium pyrophosphate and sodium citrate to an appropriate amount of deionized water, stir until completely dissolved, then slowly add the base solution in turn, continue stirring for a certain period of time to form an efficient stain removal system, dissolve papain and esterase in a small amount of warm water, slowly add them to the reactor after dissolution, stir at a low speed until evenly distributed, disperse nanohydroxyapatite in deionized water, use an ultrasonic disperser to treat for a certain period of time, dissolve strontium chloride directly in a small amount of water, then gradually add the solution of nanohydroxyapatite and strontium chloride to the base solution, continue stirring evenly, treat graphene oxide with a high shear disperser, and slowly add the base solution to form an enamel protection system;

[0021] Step 3: gradually add microcrystalline silicon dioxide and aluminum hydroxide to the base liquid, use high-speed stirring equipment to stir for a certain period of time to form a stable suspension, then add antioxidant ingredients and natural extracts in turn, continue stirring to make them evenly dispersed, add freshener, and stir at a low speed to make them evenly dispersed;

[0022] Step 4: Place the mixed solution in a vacuum environment for degassing, and adjust the ratio of glycerin to water according to the viscosity requirements to control the viscosity of the mixed solution within the range of 20,000 to 30,000 cps;

[0023] Step 5: Cool the mixture to room temperature before filling and sealing.

[0024] The beneficial effects of the present invention are:

[0025] (1) The present invention achieves efficient removal of tea stains through the synergistic effect of stain removal active ingredients (sodium pyrophosphate, sodium citrate, polyaspartic acid) and enzyme ingredients (papain, esterase). Sodium pyrophosphate chelates metal ions in tea stains, sodium citrate provides a weakly acidic environment to assist in pigment decomposition, polyaspartic acid enhances chemical chelation, and papain and esterase further decompose the protein complex covering the tea stains, making deep pigments easier to fall off. The combined action of multiple ingredients solves the problem that traditional toothpastes do not thoroughly clean tea stains, and significantly improves the stain removal efficiency.

[0026] (2) The combination of three protective ingredients, nano-hydroxyapatite, strontium chloride and graphene oxide, can repair the micropores and cracks on the tooth surface, form a smooth protective layer, and reduce the re-attachment of tea stains. Nano-hydroxyapatite replenishes enamel minerals, strontium chloride relieves tooth sensitivity and enhances acid resistance, and graphene oxide forms an antibacterial protective film that effectively prevents tea stain pigment penetration, significantly improving the long-term protection effect of teeth.

[0027] (3) The present invention uses mild surfactants (such as sodium lauroyl glutamate) and low-hardness abrasives (microcrystalline silicon dioxide, aluminum hydroxide) to avoid irritation to tooth enamel and oral mucosa and ensure the safety of the cleaning process. In addition, antioxidant ingredients (L-ascorbic acid) and natural extracts (citrus extracts) enhance the cleaning effect, giving the toothpaste a long-lasting fresh taste, meeting users' high-quality demands for oral care products. DETAILED DESCRIPTION

[0028] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below.

[0029] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0030] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The term "in one embodiment" that appears in different places in this specification does not necessarily refer to the same embodiment, nor does it refer to a separate or selective embodiment that is mutually exclusive with other embodiments.

[0031] Example 1

[0032] A highly effective tea stain removal toothpaste comprises the following components by weight: 25 parts of microcrystalline silicon dioxide, 5 parts of aluminum hydroxide, 1 part of sodium lauroyl glutamate, 0.3 parts of papain, 0.3 parts of esterase, 4.5 parts of nano-hydroxyapatite, 0.4 parts of strontium chloride, 0.02 parts of graphene oxide, 0.7 parts of L-ascorbic acid, 0.7 parts of citrus extract, 22 parts of glycerol, 18 parts of water, 0.3 parts of peppermint oil, and sodium pyrophosphate, sodium citrate, and polyaspartic acid components are shown in Table 1:

[0033] Table 1 Test data table

[0034]

[0035]

[0036] This embodiment also provides a method for preparing a highly effective tea stain removing toothpaste, which comprises the following steps:

[0037] Step 1: In a stirred reactor, add glycerin and deionized water in the formula ratio, stir evenly at a speed of 300-500rpm, maintain the temperature at 30-40℃, and completely dissolve the glycerin to form a transparent base liquid. Then, slowly add sodium lauroyl glutamate and continue stirring until it is completely dissolved to form a stable liquid phase system, providing a uniform medium for the dispersion of subsequent ingredients.

[0038] Step 2: Add polyaspartic acid, sodium pyrophosphate and sodium citrate to an appropriate amount of deionized water, stir until completely dissolved, and then slowly add the base liquid in turn to ensure uniform distribution. Continue stirring for 5 to 10 minutes to form an efficient stain removal system. Dissolve papain and esterase in a small amount of warm water (<40°C) to avoid the enzyme activity being affected by heat. After dissolution, slowly add to the reactor and stir at a low speed until evenly distributed to ensure the stability of the active ingredients. Disperse nanohydroxyapatite in deionized water and treat with an ultrasonic disperser for 5 minutes to avoid particle agglomeration. Strontium chloride is directly dissolved in a small amount of water. Then gradually add the solution of nanohydroxyapatite and strontium chloride to the base liquid and continue to stir evenly. After graphene oxide is treated with a high shear disperser, it is slowly added to form an enamel protection system.

[0039] Step 3: Gradually add microcrystalline silicon dioxide and aluminum hydroxide to the base liquid, and stir for 15 minutes using a high-speed stirring device (800-1000 rpm) to ensure that the abrasive is evenly distributed and forms a stable suspension. Then add antioxidant ingredients (L-ascorbic acid) and natural extracts (citrus extract) in turn, and continue stirring for 10 minutes to make them evenly dispersed. Add peppermint oil as a freshener and stir at a low speed for 5 minutes to avoid volatilization.

[0040] Step 4: Place the mixture in a vacuum environment (-0.08 to -0.1 MPa) and degas for 10 minutes to remove bubbles generated during the mixing process to ensure uniform toothpaste texture. Adjust the ratio of glycerin and water according to viscosity requirements to control the viscosity of the mixture within the range of 20,000 to 30,000 cps, which meets the requirements for toothpaste use.

[0041] Step 5: Cool the mixture to room temperature (25-30°C) to ensure that the stability of all active ingredients is not affected by high temperature. After cooling, use a hose filling machine to fill the toothpaste into the hose and seal it with high-frequency heat sealing equipment to ensure the airtightness of the package. After filling, conduct finished product inspections of appearance, uniformity, viscosity and pH to ensure that the quality of the toothpaste meets the expected standards.

[0042] Comparative Example 1

[0043] The invention discloses an efficient tea stain removing toothpaste, comprising the following components by weight: 25 parts of microcrystalline silicon dioxide, 5 parts of aluminum hydroxide, 1 part of sodium lauroyl glutamate, 2 parts of sodium pyrophosphate, 1.5 parts of sodium citrate, 0.8 parts of polyaspartic acid, 4.5 parts of nano-hydroxyapatite, 0.4 parts of strontium chloride, 0.02 parts of graphene oxide, 0.7 parts of L-ascorbic acid, 0.7 parts of citrus extract, 22.3 parts of glycerol, 18.3 parts of water and 0.3 parts of peppermint oil.

[0044] In this example, papain and esterase were removed, and other components remained unchanged, to verify the contribution of enzyme components to tea stain removal. Papain and esterase were replaced by glycerol and water, and the test process was the same as in Example 1.

[0045] Comparative Example 2

[0046] A toothpaste for efficiently removing tea stains and protecting teeth comprises the following components in parts by weight: 25 parts of microcrystalline silicon dioxide, 5 parts of aluminum hydroxide, 1 part of sodium lauroyl glutamate, 2 parts of sodium pyrophosphate, 2.3 parts of sodium citrate, 0.3 parts of papain, 0.3 parts of esterase, 4.5 parts of nano-hydroxyapatite, 0.4 parts of strontium chloride, 0.02 parts of graphene oxide, 0.7 parts of L-ascorbic acid, 0.7 parts of citrus extract, 22 parts of glycerol, 18 parts of water, and 0.3 parts of peppermint oil.

[0047] In this example, polyaspartic acid was removed and replaced with an equal amount of sodium citrate to verify the effect of polyaspartic acid in chelating metal ions and improving stain removal efficiency. The test process was the same as that in Example 1.

[0048] Comparative Example 3

[0049] Comparative Example 3, which is an efficient tea stain removal and tooth protection toothpaste, comprises the following components by weight: 25 parts of microcrystalline silicon dioxide, 5 parts of aluminum hydroxide, 1 part of sodium lauroyl glutamate, 22 parts of glycerol, and 18 parts of water.

[0050] In this example, only the abrasive, surfactant and wetting agent are retained to simulate the traditional toothpaste for comparison with the overall performance of the present invention. The test process is the same as that of Example 1.

[0051] Example 2

[0052] The toothpastes prepared in Example 1 and Comparative Examples 1 to 3 were subjected to enamel color measurement, and the measurement process was as follows:

[0053] (1) Preparation of in vitro tooth specimens: Fresh calf anterior teeth were selected, the root tissue was removed, and after ultrasonic cleaning, the tooth specimens were stored in 0.1 M phosphate buffer (PBS, pH 7.4). Teeth with no cracks, caries, or stains on the crown surface were selected as subsequent experimental models.

[0054] (2) Staining of in vitro tooth specimens:

[0055] Pretreatment: Immerse the prepared bovine tooth specimen in 1% hydrochloric acid, stir for 60 seconds, take it out and rinse it with clean water. Then immerse it in saturated sodium carbonate solution, stir for 60 seconds, take it out and rinse it with clean water. Finally, immerse it in 1% phytic acid solution, stir for 60 seconds, take it out and rinse it with clean water.

[0056] Prepare dye solution: Add black tea to hot water and stir evenly, then cool. Add FeCl3 solution maintained at 4°C before use. The final concentration of each component is 4.0g / L black tea and 0.05g / L FeCl3.

[0057] Staining: Immerse the pre-treated bovine tooth specimen in the staining solution and place it at 4°C for 7 days. After soaking, take out the bovine tooth and rinse it with water for 1-2 minutes.

[0058] (3) Colorimeter to measure L* value before and after brushing

[0059] After brushing teeth, a sample of the brushing solution was taken and the Fe content in the solution was detected by ICP-MS. 3+ 、Al 3+The concentration was measured, and the color of the enamel was measured with a colorimeter (L* before brushing). The specimens were randomly assigned to the sample group and the control group, with 3 pieces in each group. There was no significant difference between the groups (P>0.05). The specimens were brushed with the test substance and the control substance respectively. The sample group used it twice a day and brushed for 3 minutes. During the treatment interval, the bovine tooth specimens were immersed in artificial saliva, and the environment was maintained at 37°C to simulate the oral environment. The total test cycle was 7 days. After the brushing cycle, the color of the enamel was measured again with a colorimeter (L* after brushing), and the difference in L* values ​​before and after brushing was calculated, ΔL*=L*(after brushing)-L*(before brushing).

[0060] (4) Results analysis

[0061] Perform t-test statistical analysis on the ΔL* value. If the ΔL* value of the sample group is greater than that of the control group and there is a significant difference (P<0.05), the sample has a stain removal and whitening effect.

[0062] The measurement data are shown in Table 2.

[0063] Table 2 Measurement results

[0064] Experimental Group L* value of tooth enamel before brushing L* value of tooth enamel after brushing The difference of L* before and after brushing ΔL* Experimental Group 1 41.29 68.57 27.28 Experimental Group 2 42.1 66.83 24.73 Experimental Group 3 40.8 72.12 31.32 Experimental Group 4 41.5 67.8 26.3 Experimental Group 5 42.2 65.9 23.7 Experimental Group 6 40.9 66 25.1 Test Group 7 41 67.2 26.2 Experimental Group 8 41.6 62 20.4 Comparative Example 1 42.06 64.83 22.77 Comparative Example 2 40.66 62.36 21.7 Comparative Example 3 44.26 54.39 10.13

[0065] The metal ion removal rate of the toothpastes prepared in Example 1 and Comparative Examples 1 to 3 was measured, and the measurement process was as follows:

[0066] Step 1: Prepare metal ion standard solution.

[0067] Add 10 mg / L FeCl3 and 10 mg / L AlCl3 to 1000 mL of deionized water to simulate the metal ion environment commonly found in tea stains, and take 50 mL of the metal solution into different beakers.

[0068] Step 2: Add the test formula.

[0069] The toothpaste solutions of different test groups (test groups 1-8 and comparative examples 1-3) were added to the metal ion solution, respectively, according to the recommended dilution ratio of toothpaste (1 g toothpaste + 50 mL deionized water) to ensure that the formula ingredients work effectively.

[0070] Step 3: Stir the reaction.

[0071] Use a magnetic stirrer to stir for 30 minutes to simulate the mixing effect of toothpaste in the oral environment. During this period, the temperature is controlled at 37°C and the pH is 6.5-7.5 to ensure the simulation of the oral environment.

[0072] Step 4: Centrifugal separation.

[0073] The precipitate and solution were separated by centrifugation at 5000 rpm for 10 min, and the supernatant was used for subsequent detection.

[0074] Step 5: ICP-MS measurement of metal concentration.

[0075] Take the supernatant and add 1M HNO3 to acidify it to make Fe 3+ 、Al 3+ Stable in solution. Determination of Fe using ICP-MS or ICP-OES 3+ 、Al 3+ of the residual concentration.

[0076] Step 6: Calculate the removal rate

[0077] Removal rate calculation formula:

[0078]

[0079] Where C0 is the initial concentration of metal ions before treatment, C f is the residual concentration of metal ions after treatment.

[0080] The measured data are shown in Table 3:

[0081] Table 3 Metal ion removal rate data table

[0082]

[0083]

[0084] According to the data in Table 2 and Table 3, the following conclusions can be drawn:

[0085] 1. Experimental group 3 (sodium pyrophosphate: sodium citrate: polyaspartic acid = 2.5:1:0.8) is the optimal ratio, with the best metal chelation effect and the best tea stain removal effect. 3+ The removal rate is the highest (92%), Al 3+ The removal rate was the highest (88%), indicating that this ratio of sodium pyrophosphate and sodium citrate provided the best metal chelation and could effectively remove Fe from tea stains. 3+ and Al 3 + The addition of polyaspartic acid enhances the chelating ability and improves the overall stain removal effect.

[0086] The L* value of test group 3 changed the most, indicating that the active ingredients can more deeply decompose tea stain pigments and remove metal complexes attached to tooth enamel. Sodium pyrophosphate, sodium citrate, and polyaspartic acid have the strongest synergistic effect, enabling the toothpaste to simultaneously perform the functions of chemical dissolution, chelating metal ions, and preventing tea stains from redepositing.

[0087] 2. Too high or too low sodium pyrophosphate content will affect the chelation effect. Too little (<2.5%) will reduce the chelation ability and affect the stain removal effect. Too much (>3.0%) will lead to excessive chelation and affect the oral microenvironment.

[0088] 3. Sodium citrate helps assist chelation, but too little will reduce the acidic environment, and too much will affect the stability of the complex.

[0089] 4. Polyaspartic acid can enhance chelation and stain removal efficiency. After removing polyaspartic acid, Fe 3+ and Al 3+ The removal rate dropped by more than 20%, verifying its importance for metal ion complexation.

[0090] 5. The toothpaste of the present invention is far superior to the traditional toothpaste in terms of stain removal ability. The traditional toothpaste (Comparative Example 3) Fe 3+ The removal rate is only 40%, Al 3+ The removal rate is only 35%, and the stain removal ability is significantly lower than the formula of the present invention.

[0091] Therefore, the toothpaste of the present invention adopts a synergistic formula of sodium pyrophosphate, sodium citrate and polyaspartic acid to achieve optimal chelation and stain removal ability, which is far superior to traditional toothpaste and is suitable for effectively removing tea stains and improving oral health.

[0092] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the spirit and scope of the technical solutions of the present invention, which should all be included in the scope of the claims of the present invention.

Claims

1. A toothpaste for effectively removing tea stains, characterized in that: The composition comprises, by weight, 30-38 parts of abrasive, 1-2 parts of surfactant, 3.5-6 parts of active ingredients for stain removal, 0.4-1 parts of enzyme ingredients, 4.31-5.55 parts of protective ingredients, 0.5-1 parts of antioxidant ingredients, 0.5-1 parts of natural extracts, 35-45 parts of wetting agents, and 0.2-0.5 parts of fresh ingredients; The active stain removing ingredients are sodium pyrophosphate, sodium citrate and polyaspartic acid.

2. The highly effective tea stain removal toothpaste according to claim 1, characterized in that: The mass ratio of the sodium pyrophosphate, sodium citrate and polyaspartic acid is 2-3:1-2:0.5-1.

3. The highly effective tea stain removal toothpaste according to claim 1 or 2, characterized in that: The enzyme components are papain and esterase, wherein the mass ratio of papain to esterase is 0.2-0.5:0.2-0.

5.

4. The highly effective tea stain removal toothpaste according to claim 1 or 2, characterized in that: The friction agent is microcrystalline silicon dioxide and aluminum hydroxide, wherein the mass ratio of microcrystalline silicon dioxide to aluminum hydroxide is 25-30:5-8.

5. The highly effective tea stain removal toothpaste according to claim 2, characterized in that: The mass ratio of the sodium pyrophosphate, sodium citrate and polyaspartic acid is 2.5:1:0.

8.

6. The highly effective tea stain removal toothpaste according to claim 1 or 2, characterized in that: The protective components are nano hydroxyapatite, strontium chloride and graphene oxide, wherein the mass ratio of nano hydroxyapatite, strontium chloride and graphene oxide is 4-5: 0.3-0.5: 0.01-0.

05.

7. The highly effective tea stain removal toothpaste according to claim 1 or 2, characterized in that: The antioxidant component is L-ascorbic acid, and the surfactant is sodium lauroyl glutamate.

8. The highly effective tea stain removal toothpaste according to claim 1 or 2, characterized in that: The natural extract is citrus extract.

9. The highly effective tea stain removal toothpaste according to claim 1 or 2, characterized in that: The wetting agents are glycerol and water, wherein the mass ratio of glycerol to water is 20-25:15-20.

10. A method for preparing a highly effective tea stain removing toothpaste as claimed in any one of claims 1 to 9, characterized in that: include, Step 1: In a stirred reactor, add appropriate amount of glycerol and deionized water, stir evenly, maintain the temperature at 30-40°C, dissolve the glycerol completely to form a transparent base liquid, then slowly add sodium lauroyl glutamate, continue stirring until it is completely dissolved to form a stable liquid phase system; Step 2: Add polyaspartic acid, sodium pyrophosphate and sodium citrate to an appropriate amount of deionized water, stir until completely dissolved, then slowly add the base solution in turn, continue stirring for a certain period of time to form an efficient stain removal system, dissolve papain and esterase in a small amount of warm water, slowly add them to the reactor after dissolution, stir at a low speed until evenly distributed, disperse nanohydroxyapatite in deionized water, use an ultrasonic disperser to treat for a certain period of time, dissolve strontium chloride directly in a small amount of water, then gradually add the solution of nanohydroxyapatite and strontium chloride to the base solution, continue stirring evenly, treat graphene oxide with a high shear disperser, and slowly add the base solution to form an enamel protection system; Step 3: gradually add microcrystalline silicon dioxide and aluminum hydroxide to the base liquid, use high-speed stirring equipment to stir for a certain period of time to form a stable suspension, then add antioxidant ingredients and natural extracts in turn, continue stirring to make them evenly dispersed, add freshener, and stir at a low speed to make them evenly dispersed; Step 4: Place the mixed solution in a vacuum environment for degassing, and adjust the ratio of glycerin to water according to the viscosity requirements to control the viscosity of the mixed solution within the range of 20,000 to 30,000 cps; Step 5: Cool the mixture to room temperature before filling and sealing.

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