Traditional Chinese medicine skin lotion as well as preparation method and application thereof

Abstract

The invention discloses a traditional Chinese medicine skin lotion as well as a preparation method and application thereof. The traditional Chinese medicine skin lotion is prepared from the following raw materials in parts by weight: 35-45 parts of radix scutellariae, 35-45 parts of radix salviae miltiorrhizae, 15-25 parts of fructus gleditsiae, 15-25 parts of cacumen biotae and 2-10 parts of herba agrimoniae. According to the preparation method, the traditional Chinese medicine skin lotion is used as a raw material and is prepared by water extraction or water extraction after salicylic acid is added. The application refers to application of the traditional Chinese medicine skin lotion in preparation of medicines for treating seborrheic dermatitis. The traditional Chinese medicine skin lotion provided by the invention is simple in raw material components, active components can be effectively extracted in the preparation process, and the traditional Chinese medicine skin lotion can be effectively applied to treatment of head seborrheic dermatitis.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine skin lotion and a preparation method and application thereof. Background Art

[0002] Seborrheic dermatitis, also known as seborrheic eczema, is mainly caused by excessive sebum secretion and is a type of inflammatory skin disease. At present, the pathogenesis of the disease has not been clarified. Some studies have shown that it is mainly related to hereditary seborrhea, allergic reactions, etc. Western medicine treatment mainly uses antifungal drugs and adrenal cortical steroid hormones for symptomatic treatment, which can relieve symptoms, but cannot control recurrence. Therefore, taking traditional Chinese medicine treatment has become another optional approach.

[0003] According to the reference "Chinese Association of Traditional Chinese Medicine Dermatology Branch. Expert consensus on TCM treatment of seborrheic dermatitis [J]. Chinese Journal of Integrated Traditional Chinese and Western Medicine Dermatology and Venereology, 2020, 19(3): 283-284.", the current TCM treatment methods for seborrheic dermatitis mainly include internal treatment and external treatment. In the case of internal treatment, the main treatment is to dispel wind, heat and dampness in the acute phase, and to moisten dryness, dispel wind and relieve itching in the remission phase. Alternatively, Chinese patent medicines can be used, such as Runzao Zhiyang Capsule, Danggui Kushen Pill, Longdan Xiegan Capsule, Xiaofeng Zhiyang Granule, and Tripterygium wilfordii glycosides tablets. External treatment mainly involves Chinese medicine application and Chinese medicine bath. The Chinese medicines or Chinese patent medicines that can be used include Binghuangfule Ointment, Jianghuang Xiaocuo Liniment, Diandao Powder, Compound Phellodendron Solution Coating, and Seborrheic Washing Recipe. The existing known Chinese medicines for the treatment of seborrheic dermatitis are either complex in formulation or mainly based on conventional water extraction, which makes it difficult to effectively extract the effective active ingredients in the raw materials. Summary of the invention

[0004] The first object of the present invention is to provide a traditional Chinese medicine skin lotion with simple components.

[0005] Specifically, the raw materials for preparing the traditional Chinese medicine skin lotion include the following components in parts by weight: 35-45 parts of scutellaria baicalensis, 35-45 parts of salvia miltiorrhiza, 15-25 parts of sapodilla, 15-25 parts of orientalis leaves, and 2-10 parts of agrimony.

[0006] Preferably, the weight parts of the raw materials are: 38-42 parts of scutellaria, 38-42 parts of salvia, 19-22 parts of sapodilla, 19-22 parts of oriental arborvitae leaves, 3-6 parts of agrimony. More preferably, the weight parts of the raw materials are: 40 parts of scutellaria, 40 parts of salvia, 20 parts of sapodilla, 20 parts of oriental arborvitae leaves, 5 parts of agrimony.

[0007] The raw material components of this Chinese medicine skin lotion only include five Chinese medicinal materials, namely, scutellaria baicalensis, salvia miltiorrhiza, sapodilla, cypress leaves and agrimony. It has simple components and mild medicinal properties. The components are scientifically compatible and synergistic. It has the effects of clearing away heat and dampness, promoting blood circulation and dispelling wind, relieving itching and inflammation, and is suitable for the treatment of seborrheic dermatitis.

[0008] The second object of the present invention is to provide a method for preparing the above-mentioned Chinese medicine skin lotion.

[0009] Specifically, the preparation method is to use the above components as raw materials, decoct them in water and retain the decoction as the traditional Chinese medicine skin lotion.

[0010] Preferably, the water added for decoction is 3 to 20 times the weight of the raw material. More preferably, the water added for decoction is 8 times the weight of the raw material.

[0011] The preparation method is a conventional water decoction method, which has the advantages of being simple and easy to implement, and has good versatility and can be widely applied to existing mature equipment.

[0012] The third object of the present invention is to provide another method for preparing the above-mentioned Chinese medicine skin lotion.

[0013] Specifically, the preparation method uses the above components as raw materials, and the preparation method comprises the following steps:

[0014] 1) weighing the raw materials according to the weight of the components;

[0015] 2) adding water to the raw materials, boiling until boiling, adding salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.4-0.5:1:0.005-0.01, and keeping boiling for 10-60 minutes;

[0016] 3) adding water for dilution, wherein the weight of the water added for dilution is 3 to 5 times of the weight of the water added in step 2), filtering and collecting the filtrate to obtain the traditional Chinese medicine skin lotion.

[0017] Preferably, in step 2), the weight ratio of the raw material, water and salicylic acid is 0.5:1:0.01.

[0018] Preferably, in step 2), the boiling is maintained for 30 minutes.

[0019] Preferably, in step 3), the dilution multiple of adding water is 4 times.

[0020] The preparation method adds salicylic acid during the water extraction stage, which helps to extract the active ingredients in the raw material medicine and increase the content in the extract. In addition, salicylic acid itself has keratinization promoting, antipruritic and antibacterial effects, which can enhance the overall efficacy of the traditional Chinese medicine skin lotion by taking multiple approaches.

[0021] The fourth object of the present invention is to provide the application of the above-mentioned Chinese medicine skin lotion.

[0022] Specifically, the application is the application of the above-mentioned traditional Chinese medicine skin lotion or the traditional Chinese medicine skin lotion prepared by the above-mentioned preparation method in the preparation of a drug for treating seborrheic dermatitis.

[0023] The Chinese medicine skin lotion is suitable for treating seborrheic dermatitis on the head. When using the lotion, the patient's hair is first washed with clean water, and then 10 to 30 ml of the lotion is mixed with warm water. The mixed liquid is used to rinse the patient's scalp with or without clean water, twice a week, and a course of treatment is 4 weeks of continuous use. DETAILED DESCRIPTION

[0024] The raw materials of the Chinese medicine skin lotion of the present invention include the following components in parts by weight: 35-45 parts of scutellaria baicalensis, 35-45 parts of salvia miltiorrhiza, 15-25 parts of sapodilla, 15-25 parts of oriental arborvitae leaves, and 2-10 parts of agrimony. The following ratio is the most commonly used scheme: 40 parts of scutellaria baicalensis, 40 parts of salvia miltiorrhiza, 20 parts of sapodilla, 20 parts of oriental arborvitae leaves, and 5 parts of agrimony.

[0025] In the formula: Scutellaria baicalensis is the dried root of Scutellaria baicalensis Georgi, a plant of the Lamiaceae family; Salvia miltiorrhiza is the dried root and rhizome of Salvia miltiorrhiza Bunge., a plant of the Lamiaceae family; Gleditsia sinensis Lam. is the ripe fruit of Gleditsia sinensis Lam., a plant of the Leguminosae family; Platycladus orientalis leaves are the dried branches and leaves of Platycladus orientalis (L.) Franco, a plant of the Cupressaceae family; Agrimonia pilosa Ledeb. is the dried aerial part of Agrimonia pilosa Ledeb., a plant of the Rosaceae family.

[0026] The inventor of the present invention has summarized after combining clinical experience: the conventional treatment principle of Chinese medicine for seborrheic dermatitis is mainly based on dispelling wind, clearing heat and removing dampness, moistening dryness, dispelling wind and relieving itching, so most of the Chinese medicinal materials that clear heat and dry dampness, purge fire and detoxify, and kill insects and relieve itching are used as medicine. However, this type of Chinese medicine is limited to the appearance of seborrheic dermatitis and cannot accurately grasp the pathogenesis of the disease. The symptoms of seborrheic dermatitis are similar to the "white scaly wind" in traditional Chinese medicine. The occurrence of this disease is closely related to the lungs, mainly due to human weakness, which is easy to cause wind evil invasion, or excessive fatigue, Yang Qi leakage, causing skin malnutrition; so the medicinal materials that invigorate qi and promote blood circulation should also be added to replenish human weakness and improve skin condition. Specifically in the prescription of the present invention, Astragalus membranaceus, invigorates qi and consolidates the exterior, supports toxins and discharges pus; Salvia miltiorrhiza, removes blood stasis and relieves pain, promotes blood circulation and dredges the menstruation. Astragalus membranaceus and Salvia miltiorrhiza are a pair of medicines with the effects of invigorating qi and promoting blood circulation, and are the monarch medicines. Gleditsia sinensis can clear the orifices, remove phlegm, remove wind, and kill insects. It also has the effect of cleaning the excessive oil on the scalp; Platycladus orientalis leaves can cool the blood, stop bleeding, eliminate rheumatism, and disperse swelling and poison; Gleditsia sinensis and Platycladus orientalis leaves are both ministerial drugs, which play the role of antibacterial, heat-clearing and dampness-drying. Agrimony has the effects of astringent hemostasis and insecticide, which is used to make up for the anticoagulant effect of Salvia miltiorrhiza and the hemolytic effect of Gleditsia sinensis, reduce the stimulation to skin lesions and promote the recovery of skin lesions, and strengthen the antibacterial and antipruritic effects of Gleditsia sinensis and Platycladus orientalis, and is used as an adjuvant of the whole prescription.

[0027] The preparation method of the present invention can adopt a conventional water decoction method, but the following salicylic acid water extraction method is preferred. The salicylic acid water extraction method comprises the following steps: 1) weighing raw materials according to the weight of the above components; 2) adding water to the raw materials, boiling until boiling, adding salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.4-0.5:1:0.005-0.01, and keeping boiling for 10-60 minutes;

[0028] 3) adding water for dilution, wherein the weight of the water added for dilution is 3 to 5 times of the weight of the water added in step 2), filtering and collecting the filtrate to obtain the traditional Chinese medicine skin lotion.

[0029] The salicylic acid water extraction method of the present invention is to add the salicylic acid when the water is boiling, and its higher solubility in hot water can be used to increase its concentration during hydrolysis, which is beneficial to destroying the cell wall structure of the medicinal material and releasing more effective components. Moreover, the addition of salicylic acid can increase the compatibility, which is beneficial to extracting and increasing the content of active ingredients such as baicalin, tanshinone and terpenes in Platycladus orientalis leaves in the extract. After the boiling water extraction, in order to avoid excessive salicylic acid content in the water extract, thereby irritating the scalp, and in accordance with the characteristic of low solubility of salicylic acid at room temperature, water dilution is required. The low concentration of salicylic acid in the diluted extract can also play the effects of antibacterial, antipruritic, and keratinization promotion.

[0030] The present invention is described and explained below by means of several embodiments. It should be understood that the following embodiments are not intended to limit the present invention.

[0031] Example 1

[0032] 1) Weigh the following Chinese medicine raw materials: 40 parts of Scutellaria baicalensis, 40 parts of Salvia miltiorrhiza, 20 parts of Gleditsia sinensis, 20 parts of Platycladus orientalis, and 5 parts of Agrimoniae. 2) Add water to the raw materials, boil until boiling, add salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.5:1:0.01, keep boiling for 30 minutes. 3) Add water to dilute, the water added for dilution is 4 times the weight of the water added in step 2), filter and take the filtrate to prepare a Chinese medicine skin lotion.

[0033] Example 2

[0034] 1) Weigh the following Chinese medicine raw materials: 38 parts of Scutellaria baicalensis, 40 parts of Salvia miltiorrhiza, 22 parts of Gleditsia sinensis, 19 parts of Platycladus orientalis, and 5 parts of Agrimoniae. 2) Add water to the raw materials, boil until boiling, add salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.5:1:0.005, keep boiling for 20 minutes. 3) Add water to dilute, the water added for dilution is 5 times the weight of the water added in step 2), filter and take the filtrate to prepare a Chinese medicine skin lotion.

[0035] Example 3

[0036] 1) Weigh the following Chinese medicine raw materials: 39 parts of Scutellaria baicalensis, 42 parts of Salvia miltiorrhiza, 19 parts of Gleditsia sinensis, 21 parts of Platycladus orientalis, and 6 parts of Agrimoniae. 2) Add water to the raw materials, boil until boiling, add salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.4:1:0.008, keep boiling for 60 minutes. 3) Add water to dilute, the water added for dilution is 3 times the weight of the water added in step 2), filter and take the filtrate to prepare a Chinese medicine skin lotion.

[0037] Example 4

[0038] 1) Weigh the following Chinese medicine raw materials: 42 parts of Scutellaria baicalensis, 38 parts of Salvia miltiorrhiza, 20 parts of Gleditsia sinensis, 22 parts of Platycladus orientalis, and 3 parts of Agrimoniae. 2) Add water to the raw materials, boil until boiling, add salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.45:1:0.01, keep boiling for 10 minutes. 3) Add water to dilute, the water added for dilution is 4 times the weight of the water added in step 2), filter and take the filtrate to prepare a Chinese medicine skin lotion.

[0039] Example 5

[0040] 1) Weigh the following Chinese medicine raw materials: 40 parts of Scutellaria baicalensis, 45 parts of Salvia miltiorrhiza, 15 parts of Gleditsia sinensis, 21 parts of Platycladus orientalis, and 10 parts of Agrimoniae. 2) Add water to the raw materials, boil until boiling, add salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.4:1:0.009, keep boiling for 60 minutes. 3) Add water to dilute, the water added for dilution is 3 times the weight of the water added in step 2), filter and take the filtrate to prepare a Chinese medicine skin lotion.

[0041] Example 6

[0042] 1) Weigh the following Chinese medicine raw materials: 35 parts of Scutellaria baicalensis, 41 parts of Salvia miltiorrhiza, 25 parts of Gleditsia sinensis, 15 parts of Platycladus orientalis, and 7 parts of Agrimoniae. 2) Add water to the raw materials, boil until boiling, add salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.5:1:0.005, keep boiling for 40 minutes. 3) Add water to dilute, the water added for dilution is 5 times the weight of the water added in step 2), filter and take the filtrate to prepare a Chinese medicine skin lotion.

[0043] Example 7

[0044] 1) Weigh the following Chinese medicine raw materials: 45 parts of Scutellaria baicalensis, 35 parts of Salvia miltiorrhiza, 20 parts of Gleditsia sinensis, 25 parts of Platycladus orientalis, and 2 parts of Agrimoniae. 2) Add water to the raw materials, boil until boiling, add salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.45:1:0.01, keep boiling for 10 minutes. 3) Add water to dilute, the water added for dilution is 4.5 times the weight of the water added in step 2), filter and take the filtrate to prepare a Chinese medicine skin lotion.

[0045] Example 8

[0046] 1) Weigh the following Chinese medicine raw materials: 40 parts of Scutellaria baicalensis, 40 parts of Salvia miltiorrhiza, 20 parts of Gleditsia sinensis, 20 parts of Platycladus orientalis leaves, and 5 parts of Agrimoniae. 2) Use conventional decoction method to keep the decoction as Chinese medicine skin lotion, and the water added for decoction is 8 times the weight of the raw materials.

[0047] Comparative Example 1

[0048] 1) Weigh the following Chinese medicine raw materials: 40 parts of Scutellaria baicalensis, 40 parts of Sophora flavescens, 20 parts of Gleditsia sinensis, 20 parts of Platycladus orientalis leaves, and 5 parts of Agrimoniae. 2) Add water to the raw materials, boil until boiling, add salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.5:1:0.01, keep boiling for 30 minutes. 3) Add water to dilute, the water added for dilution is 4 times the weight of the water added in step 2), filter and take the filtrate to prepare a Chinese medicine skin lotion.

[0049] Comparative Example 2

[0050] 1) Weigh the following Chinese medicine raw materials: 40 parts of Scutellaria baicalensis, 40 parts of Salvia miltiorrhiza, 20 parts of Gleditsia sinensis, and 20 parts of Platycladus orientalis leaves. 2) Add water to the raw materials, boil until boiling, add salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.5:1:0.01, keep boiling for 30 minutes. 3) Add water to dilute, the water added for dilution is 4 times the weight of the water added in step 2), filter and take the filtrate to prepare a Chinese medicine skin lotion.

[0051] Comparative Example 3

[0052] 1) Weigh the following Chinese medicine raw materials: 40 parts of Scutellaria baicalensis, 40 parts of Salvia miltiorrhiza, 20 parts of Gleditsia sinensis, 20 parts of Platycladus orientalis leaves, and 5 parts of Agrimoniae. 2) Prepare by conventional decoction method, with the water added for decoction being 8 times the weight of the raw materials, retain the decoction and add 0.2wt% of salicylic acid as a Chinese medicine skin lotion.

[0053] Test Example 1: Clinical Observation

[0054] 1. General Information

[0055] A total of 240 patients with seborrheic dermatitis of the scalp who were admitted to the applicant's medical institution from January 2022 to December 2024 were selected as research subjects and randomly divided into 6 groups, with 40 cases in each group, aged 18 to 65 years old, with an average age of (30.6±7.4) years old.

[0056] 2. Treatment Methods

[0057] Group 1 is the control group, which uses 2.5% selenium disulfide lotion for external washing, twice a week, for 4 weeks. Groups 2 to 6 are experimental groups, which use the Chinese medicine skin lotions prepared in Example 1, Example 8, Comparative Example 1, Comparative Example 2 and Comparative Example 3, respectively. When using, 20 ml of the lotion is mixed with warm water and used to wash the patient's scalp, twice a week, for 4 weeks.

[0058] 3. Observation indicators

[0059] This study observed the recurrence and treatment effect after treatment. The patients were considered to have significant effect if their symptoms of macules, itching, scaling, greasiness and hair loss disappeared completely; the patients were considered to have effective effect if their symptoms of macules, itching, scaling, greasiness and hair loss improved significantly; the patients were considered to have no improvement if their symptoms of macules, itching, scaling, greasiness and hair loss did not improve at all.

[0060] All cases in each group were followed up for one month after one course of treatment (four weeks). The follow-up methods were as follows: ① The test cases were followed up once two weeks after the end of treatment, for a total of one month; ② The recurrence rate of the cured patients was observed to observe whether new lesions appeared in the cured skin lesions or whether the itching symptoms reappeared; ③ The follow-up was carried out in the form of re-examination, telephone or Internet, and the recurrence rate after one month was compared; Recurrence rate = number of relapse cases / number of cured cases × 100%.

[0061] 4. Statistical methods

[0062] SPSS 17.0 software was used to analyze the data. The measurement data were expressed as (mean ± standard deviation) and the t test was used; the enumeration data were expressed as (n, %) and the x test was used. 2 Test, P < 0.05 indicated that the difference was statistically significant.

[0063] 5. Results

[0064] 1) Comparison of treatment effects

[0065] Comparison before and after treatment showed that the control group had 15 markedly effective cases, 16 effective cases, and 9 ineffective cases; Example 1 had 28 markedly effective cases, 10 effective cases, and 2 ineffective cases; Example 8 had 13 markedly effective cases, 17 effective cases, and 10 ineffective cases; Comparative Example 1 had 16 markedly effective cases, 19 effective cases, and 5 ineffective cases; Comparative Example 2 had 12 markedly effective cases, 22 effective cases, and 6 ineffective cases; Comparative Example 3 had 15 markedly effective cases, 17 effective cases, and 8 ineffective cases. The differences were statistically significant, and the results are shown in Table 1 below:

[0066] Table 1. Comparison of treatment effects

[0067] Group n Significantly effective (n) Effective(n) Invalid(n) Total Effectiveness Control group 40 15 16 9 77.5％ Example 1 40 28 10 2 95.0％ Example 8 40 13 17 10 75.0％ Comparative Example 1 40 16 19 5 87.5％ Comparative Example 2 40 12 22 6 85.0％ Comparative Example 3 40 15 17 8 80.0％

[0068] 2) Comparison of recurrence

[0069] The markedly effective and effective patients were followed up: a total of 31 cases were followed up in the control group, 8 of which relapsed, with a relapse rate of 25.8%; a total of 37 cases were followed up in the embodiment 1 group (1 case was out of the test), 2 of which relapsed, with a relapse rate of 5.56%; a total of 30 cases were followed up in the embodiment 8 group, 6 of which relapsed, with a relapse rate of 20%; a total of 35 cases were followed up in the comparative example 1 group, 4 of which relapsed, with a relapse rate of 11.43%; a total of 34 cases were followed up in the comparative example 2 group, 3 of which relapsed, with a relapse rate of 8.82%; a total of 32 cases were followed up in the comparative example 3 group, 9 of which relapsed, with a relapse rate of 28.13%.

[0070] 3) Discussion of results

[0071] From the above table and the recurrence statistics, it can be seen that the Chinese medicine skin lotion provided by the present invention can achieve a therapeutic effect similar to that of the selenium disulfide lotion, and the salicylic acid extraction method of the present invention can achieve a better therapeutic effect and a lower recurrence rate. Specifically, it can be seen from the comparison of Example 1, Comparative Example 1 and Comparative Example 2 that the various formulations in the formula of the present invention cooperate with each other, and replacing or reducing some or a certain component thereof will affect the overall therapeutic effect of the Chinese medicine skin lotion; it can be seen from the comparison of Example 1, Example 8 and Comparative Example 3 that the addition of salicylic acid not only utilizes its own inhibitory effect on seborrheic dermatitis, but also affects the technical effect of the entire extraction process, thereby affecting the final therapeutic effect.

[0072] It should be understood that all the above embodiments are illustrative rather than restrictive, and various modifications and changes made by those skilled in the art to the specific embodiments described above under the conception of the present invention should be within the protection scope of the present invention.

Claims

1. A Chinese medicine skin lotion, characterized in that: The raw materials for preparing the traditional Chinese medicine skin lotion comprise the following components in parts by weight: 35-45 parts of scutellaria baicalensis, 35-45 parts of salvia miltiorrhiza, 15-25 parts of sapodilla, 15-25 parts of oriental arborvitae leaves and 2-10 parts of agrimony.

2. The Chinese medicine skin lotion according to claim 1, characterized in that The components of the raw materials are as follows: 38-42 parts of scutellaria baicalensis, 38-42 parts of salvia miltiorrhiza, 19-22 parts of sapodilla, 19-22 parts of oriental arborvitae leaves, and 3-6 parts of agrimony.

3. The Chinese medicine skin lotion according to claim 1, characterized in that The components of the raw materials are as follows: 40 parts of scutellaria baicalensis, 40 parts of salvia miltiorrhiza, 20 parts of gleditsia sinensis, 20 parts of arborvitae leaves, and 5 parts of agrimony.

4. A method for preparing a Chinese medicine skin lotion, characterized in that: The components described in any one of claims 1 to 3 are used as raw materials, and the decoction is retained after decocting in water as the traditional Chinese medicine skin lotion.

5. A method for preparing a Chinese medicine skin lotion, characterized in that: The preparation method is prepared by using the component according to any one of claims 1 to 3 as raw materials, and the preparation method comprises the following steps: 1) weighing the raw materials according to the weight of the components; 2) adding water to the raw materials, boiling until boiling, adding salicylic acid, the weight ratio of raw materials, water and salicylic acid is 0.4-0.5:1:0.005-0.01, and keeping boiling for 10-60 minutes; 3) adding water for dilution, wherein the weight of the water added for dilution is 3 to 5 times of the weight of the water added in step 2), filtering and collecting the filtrate to obtain the traditional Chinese medicine skin lotion.

6. The preparation method according to claim 5, characterized in that: In step 2), the weight ratio of the raw material, water and salicylic acid is 0.5:1:0.

01.

7. The preparation method according to claim 5, characterized in that: In step 2), the boiling is maintained for 30 minutes.

8. The preparation method according to claim 5, characterized in that: In step 3), the dilution multiple is 4 times.

9. Use of the traditional Chinese medicine skin lotion according to any one of claims 1 to 3 or the traditional Chinese medicine skin lotion prepared by the preparation method according to any one of claims 4 to 8 in the preparation of a medicament for treating seborrheic dermatitis.