Traditional Chinese medicine composition for treating diabetes and polycystic ovarian syndrome and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating diabetes and polycystic ovarian syndrome and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-30 parts of raw radix astragali, 10-30 parts of raw radix rehmanniae, 10-20 parts of rhizoma polygonati, 10-20 parts of raw cortex eucommiae, 10-20 parts of herba taxilli, 10-20 parts of rhizoma anemarrhenae, 10-30 parts of mulberry, 10-20 parts of rhizoma dioscoreae, 10-20 parts of semen raphani and 10-30 parts of radix salviae miltiorrhizae. The traditional Chinese medicine composition is prepared from, by weight, 10-20 parts of radix angelicae sinensis, 10-30 parts of radix cyathulae, 10-30 parts of plantain herb, 10-30 parts of raw coix seeds and 10-30 parts of lilies. The traditional Chinese medicine composition can improve insulin, promote insulin secretion, improve glucose tolerance and reduce blood sugar, the blood sugar can be kept normal after drug withdrawal, the existing therapy of lifelong drug taking of diabetics can be solved, complications of the diabetics are cut off, and meanwhile, the symptom of PCOS can be effectively relieved and fertility can be promoted by improving insulin resistance.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating diabetes and polycystic ovary syndrome and a preparation method thereof. Background Art

[0002] Diabetes is a global chronic metabolic disease, which is mainly manifested by high blood sugar. Long-term high blood sugar status will damage various organs of the body, especially the eyes, kidneys, heart, blood vessels and nervous system. With the change of lifestyle and the intensification of the aging trend of the population, the incidence of diabetes has increased year by year and has become one of the major diseases threatening human health. The current medical treatment methods are that diabetics take hypoglycemic drugs and inject insulin for life. The treatment method is only a temporary solution and not a permanent solution. The side effects of the drugs will gradually increase the burden on the body, and various complications caused by diabetes such as hypertension and heart disease will occur. Traditional Chinese medicine understands diabetes as a thirst disease and blames it on "yin deficiency and dryness". Its treatment is based on "nourishing yin and clearing heat".

[0003] Insulin resistance is a major accomplice in the pathogenesis of polycystic ovary syndrome (PCOS). Insulin resistance refers to the weakened response of the body's tissues to insulin, which causes the pancreatic beta cells to secrete more insulin to maintain normal blood sugar levels. Among PCOS patients, up to 40% to 70% of patients have insulin resistance, which increases their risk of type 2 diabetes and exacerbates the symptoms of PCOS.

[0004] Insulin resistance can lead to a series of metabolic disorders, such as abdominal obesity, acanthosis nigricans, irregular menstruation, acne, hirsutism and hair loss. These symptoms, in turn, affect the quality of life and fertility of PCOS patients. The treatment of PCOS with insulin resistance currently usually includes improving lifestyle such as increasing exercise, adjusting diet, and using medications, such as insulin sensitizers such as metformin. These treatments are aimed at improving insulin resistance and relieving the symptoms of PCOS, but they also add some side effects to the body and are not the most ideal therapeutic effects. Insulin resistance is a major accomplice of PCOS. By improving insulin resistance, the symptoms of PCOS can be effectively relieved, fertility can be promoted, and the quality of life of patients can be improved. Summary of the invention

[0005] In view of the deficiencies of the prior art, the present invention provides a Chinese medicine composition for treating diabetes and polycystic ovary syndrome and a preparation method thereof. The method regulates insulin, improves insulin cell function, promotes insulin secretion, improves glucose tolerance and lowers blood sugar, thereby treating diabetes and polycystic ovary syndrome. The technical scheme is as follows: A Chinese medicine composition for treating diabetes and polycystic ovary syndrome comprises the following raw materials in parts by weight: 10-30 parts of raw astragalus, 10-30 parts of raw rehmannia, 10-20 parts of polygonatum, 10-20 parts of raw eucommia, 10-20 parts of viburnum, 10-20 parts of anemarrhena, 10-30 parts of mulberry, 10-20 parts of yam, 10-20 parts of radish seeds, 10-30 parts of salvia miltiorrhiza, 10-20 parts of angelica, 10-30 parts of cyathula, 10-30 parts of plantain, 10-30 parts of raw coix seeds and 10-30 parts of lily.

[0006] Furthermore, the raw materials in parts by weight are preferably: 16 parts of raw astragalus, 20 parts of raw rehmannia, 12 parts of polygonatum, 13 parts of raw eucommia, 15 parts of mistletoe, 16 parts of anemarrhena, 21 parts of mulberries, 18 parts of yam, 13 parts of radish seeds, 22 parts of salvia miltiorrhiza, 17 parts of angelica, 19 parts of cyathula, 23 parts of plantain, 22 parts of raw coix seeds, and 20 parts of lily.

[0007] Raw Astragalus: Lowers blood sugar, replenishes Qi and blood, tastes sweet, is slightly warm, is non-toxic, enters the lung and spleen meridians, supports ulcerated sores internally, promotes tissue growth and heals wounds, strengthens the exterior and relieves night sweats, and fills the pores.

[0008] Shengdihuang: Lowers blood sugar, nourishes yin, tastes sweet and bitter, is cold and non-toxic, and enters the five meridians of heart, liver, spleen, lung, and kidney. It cools the irritability and heat of heart fire, relieves damp heat of spleen earth, stops epistaxis in the lung meridian, and removes blood heat of liver wood. Cold qi benefits the kidney, and when kidney qi is full, the opening and closing are like a pattern, blood is harmonious and evil is eliminated, and arthritis is cured. The kidney governs the bones, and when the qi is cold and benefits the kidney, the water is sufficient and the bone marrow is full.

[0009] Polygonatum: It lowers blood sugar, tastes sweet, is mild and non-toxic, and enters the spleen, lung, and kidney meridians. It replenishes the middle qi, eliminates rheumatism, and calms the five internal organs.

[0010] Raw Eucommia: Spicy and sweet, warm and non-toxic, enters the kidney meridian. It is used to treat dampness and itching under the genitals, residual urine, strengthen the will, strengthen the tendons and bones, nourish the kidneys and stop waist pain, and regulate the yin and yang in the kidneys.

[0011] Mulberry parasite: bitter, flat, non-toxic, enters the foot Shaoyin kidney and foot Jueyin liver meridians. Strengthens bones and tendons and regulates the yin and yang in the kidney.

[0012] Anemarrhena: Lowers blood sugar, nourishes yin and reduces fire, bitter in taste, cold in nature and non-toxic, enters the kidney meridian. It can relieve kidney fire without roots, treat bone steaming with sweat, stop the excess of yang in asthenia, and nourish the source of yin.

[0013] Mulberry: It lowers blood sugar, nourishes yin and tonifies the kidney, is sweet, has a flat qi, is non-toxic, and enters the foot-sun bladder and foot-jueyin liver meridians. It quenches thirst, produces body fluids, and reduces swelling and promotes diuresis.

[0014] Chinese Yam: It lowers blood sugar, tastes sweet, is warm and non-toxic, and enters the spleen, lung and kidney meridians. It replenishes yin deficiency, reduces swelling and hardness, strengthens spleen qi, grows muscles, and strengthens tendons and bones.

[0015] Radish seeds: spicy, sweet, neutral, non-toxic, enter the spleen, stomach, and lung meridians, help digestion and eliminate accumulation, descend qi and resolve phlegm, relieve qi and wheezing, resolve phlegm and break depression.

[0016] Danshen: bitter, slightly cold and non-toxic, enters the heart meridian. It nourishes the mind and calms the spirit, breaks up knots and eliminates symptoms, eliminates carbuncle and swelling, discharges pus and relieves pain, grows flesh, treats wind evil and heat, red eyes, madness, pain in joints, paralysis of limbs. It breaks up old blood and replenishes new blood.

[0017] Angelica: sweet and spicy, warm and non-toxic, enters the heart, liver, stomach, lungs, and large intestine. Angelica is a blood medicine. The heart governs blood, the liver stores blood, and the spleen wraps blood, so they all enter. It is divided into four uses, which is also the way to be close to the upper and the lower.

[0018] Sichuan Cyathula: Lowers blood sugar, bitter and sour, neutral, non-toxic, enters the kidney meridian. Replenishes essence and qi, benefits waist and knees, fills bone marrow, removes brain leakage, removes cold and dampness, breaks blood clots, and regulates menstruation.

[0019] Plantain: sweet, cold, non-toxic, enters the liver, kidney, lung, and small intestine meridians, clears blood heat, treats vomiting and epistaxis, promotes urination, relieves stranguria, and improves eyesight.

[0020] Raw coix seed: sweet, slightly cold and non-toxic, enters the lung, spleen, liver, stomach, large intestine and five meridians. It benefits the stomach, eliminates edema, removes rheumatism, treats beriberi, treats pulmonary tuberculosis, and strengthens the spleen and stomach.

[0021] Lily: sweet in taste, mild in nature and non-toxic, enters the heart, lungs, large and small intestines. It can cure ghosts and evil spirits, cough and spit blood due to heat, moisten the lungs and calm the mind, calm the nerves and improve the will, promote urination and defecation, and replenish the middle and benefit the qi.

[0022] The second purpose of the present invention is achieved by the following technical scheme: weigh the Chinese medicine components according to the formula, wash and dry them, then break the wall of the dried Chinese medicine, immediately put the broken Chinese medicine into a decoction bag under sterile and dust-free conditions, and then put the decoction bag into an automatic two-decoction decoction machine, add 350-500 ml of pure water and soak for 30-45 minutes, and boil it into 100-150 ml of Chinese medicine oral liquid.

[0023] Furthermore, a Chinese medicine composition for treating diabetes and polycystic ovary syndrome is used in the preparation of medicines for treating diabetes and polycystic ovary syndrome.

[0024] Compared with the prior art, the present invention has the following beneficial effects: The invention adopts raw astragalus, raw rehmannia and polygonatum as main drugs for invigorating qi, raw eucommia, villous plant, rhizoma anemarrhenae, mulberry and yam as assistant drugs for regulating yin and yang in the kidney, radish seeds, salvia miltiorrhiza, angelica and rhizoma cyrtonemae as adjuvant drugs for treating both phlegm and blood stasis and nourishing blood, activating blood circulation and removing blood stasis, and plantain, raw coix seed and lily as guiding drugs for penetrating dampness and facilitating defecation and urinating. The medicine is used strictly and can increase insulin and promote insulin secretion, improve glucose tolerance and lower blood sugar. Blood sugar can be kept normal after stopping the medicine. The existing treatment method of lifelong medication for diabetic patients can be solved, and the occurrence of complications of diabetic patients is cut off. At the same time, by improving insulin resistance, the symptoms of PCOS can be effectively alleviated and fertility can be promoted, so that the quality of life of patients can be improved and medical expenses can be greatly reduced. DETAILED DESCRIPTION

[0025] The technical solution of the present invention is clearly and completely described below in conjunction with specific embodiments. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention. Example

[0026] A traditional Chinese medicine composition for treating diabetes and polycystic ovary syndrome comprises the following raw materials: 10-30g of raw astragalus, 10-30g of raw rehmannia, 10-20g of polygonatum, 10-20g of raw eucommia, 10-20g of parasitic plant, 10-20g of anemarrhena, 10-30g of mulberry, 10-20g of yam, 10-20g of radish seed, 10-30g of salvia miltiorrhiza, 10-20g of angelica, 10-30g of cyathula, 10-30g of plantain, 10-30g of raw coix seed and 10-30g of lily.

[0027] Further, take the raw materials: 16g raw astragalus, 20g raw rehmannia, 12g polygonatum, 13g raw eucommia, 15g mistletoe, 16g anemarrhena, 21g mulberry, 18g yam, 13g radish seed, 22g salvia miltiorrhiza, 17g angelica, 19g cyathula, 23g plantain, 22g raw coix seed, and 20g lily.

[0028] The above raw materials are washed and air-dried, and then the wall of the air-dried traditional Chinese medicine is broken, and the broken traditional Chinese medicine is immediately put into a decoction bag under sterile and dust-free conditions, and then the decoction bag is put into an automatic two-decoction medicine decocting machine, and 350-500 ml of pure water is added and soaked for 30-45 minutes, and boiled into 100-150 ml of traditional Chinese medicine oral liquid to obtain a traditional Chinese medicine composition for treating diabetes and polycystic ovary syndrome.

[0029] The invention discloses an application of a Chinese medicine composition for treating diabetes and polycystic ovary syndrome in preparing medicines for treating diabetes and polycystic ovary syndrome.

[0030] Dosage: Have the patient drink 60 ml of Chinese medicine oral liquid three times a day, or take broken-wall Chinese medicine powder capsules or Chinese medicine pills with the same efficacy for 1-3 months.

[0031] Classic case: Case 1: Wu, male, 58 years old, with family hereditary diabetes, took 16 parts of raw astragalus, 20 parts of raw rehmannia, 12 parts of polygonatum, 13 parts of raw eucommia, 15 parts of mistletoe, 16 parts of anemarrhena, 21 parts of mulberry, 18 parts of yam, 13 parts of radish seeds, 22 parts of salvia miltiorrhiza, 17 parts of angelica, 19 parts of cyathula, 23 parts of plantain, 22 parts of raw coix seeds, 20 parts of lily, after taking the medicine for 30 days, his fasting blood sugar dropped from 12 to 7.5-8.0, and his blood pressure dropped from 190 / 145 to 140 / 90. He stopped taking the above prescription and used western medicine for one month, and his blood sugar remained at 7.5-8.0. He continued to take the above prescription for 20 days. His fasting blood sugar was 5.9 after stopping the medicine for 3 days.

[0032] Case 2: Rong, male, 47 years old, with a history of diabetes for 11 years, took 13 parts of raw astragalus, 21 parts of raw rehmannia, 15 parts of polygonatum, 12 parts of raw eucommia, 13 parts of villous herb, 16 parts of anemarrhena, 20 parts of mulberry, 19 parts of yam, 12 parts of radish seeds, 25 parts of salvia miltiorrhiza, 12 parts of angelica, 14 parts of cyathula, 21 parts of plantain, 20 parts of raw coix seeds, 22 parts of lily, took the medicine for 50 days, and his fasting blood sugar was 6.1 after 5 days of stopping the medicine.

[0033] The above descriptions are merely embodiments of the present invention. It should be pointed out that, for those skilled in the art, various changes, modifications, substitutions and variations can be made to these embodiments without departing from the technical principles of the present invention. These changes, modifications, substitutions and variations should also be regarded as the scope of protection of the present invention.

Claims

1. A Chinese medicine composition for treating diabetes and polycystic ovary syndrome, which regulates insulin, improves insulin cell function, promotes insulin secretion, improves glucose tolerance and lowers blood sugar, thereby treating diabetes and polycystic ovary syndrome, characterized in that: The raw materials in parts by weight include: 10-30 parts of raw astragalus, 10-30 parts of raw rehmannia, 10-20 parts of polygonatum, 10-20 parts of raw eucommia, 10-20 parts of mistletoe, 10-20 parts of anemarrhena, 10-30 parts of mulberries, 10-20 parts of yam, 10-20 parts of radish seeds, 10-30 parts of salvia miltiorrhiza, 10-20 parts of angelica, 10-30 parts of cyathula, 10-30 parts of plantain, 10-30 parts of raw coix seeds, and 10-30 parts of lily.

2. A Chinese medicine composition for treating diabetes and polycystic ovary syndrome according to claim 1, characterized in that: The raw materials in parts by weight are preferably: 16 parts of raw astragalus, 20 parts of raw rehmannia, 12 parts of polygonatum, 13 parts of raw eucommia, 15 parts of villous plant, 16 parts of anemarrhena, 21 parts of mulberries, 18 parts of yam, 13 parts of radish seeds, 22 parts of salvia miltiorrhiza, 17 parts of angelica, 19 parts of cyathula, 23 parts of plantain, 22 parts of raw coix seeds, and 20 parts of lily.

3. A method for preparing a Chinese medicine composition for treating diabetes and polycystic ovary syndrome according to claim 1 or 2, characterized in that: The following steps are involved: Weigh each component of the Chinese medicine according to the formula, wash and dry it in the sun, then break the wall of the dried Chinese medicine, put the broken Chinese medicine into a decoction bag immediately under sterile and dust-free conditions, then put the decoction bag into an automatic two-decoction medicine decocting machine, add 350-500 ml of pure water and soak for 30-45 minutes, and boil it into 100-150 ml of Chinese medicine oral liquid.

4. Use of the Chinese medicine composition for treating diabetes and polycystic ovary syndrome according to claim 1 or 2 in the preparation of medicines for treating diabetes and polycystic ovary syndrome.