A medicinal and edible health product containing papaya and its application

Abstract

The present invention discloses a health product that is both a medicine and a food. The raw materials include the following components in the following proportions by weight: 15-20 parts papaya extract, 8-10 parts chicory root extract, 5-6 parts composite fermentation extract, 5-7 parts cornus officinalis extract, 3-6 parts turmeric, and 2-3 parts plantain. The present invention aims to address the problems of poor efficacy and single ingredients in existing health products. The raw materials used are all natural plant extracts that are both medicine and food. This health product achieves comprehensive health benefits through multiple mechanisms (such as uric acid reduction, anti-inflammatory and analgesic effects, antioxidant effects, and metabolic and immune regulation).

Description

Technical Field

[0001] The present invention relates to the technical field of health care products, in particular to a health care product containing papaya and having medicinal and edible properties and application thereof. Background Art

[0002] "Medicine and food have the same origin" refers to the concept of certain foods possessing dual properties as both medicine and food, allowing them to be used as both daily ingredients and as medicinal materials for healthcare. This concept, originating from ancient Chinese medicine, emphasizes the use of natural foods to regulate bodily functions and prevent and treat disease. Common ingredients with this dual nature include Chinese yam, wolfberry, astragalus, and red dates. As innovative products that combine natural ingredients with traditional Chinese medicine theory, these health supplements demonstrate tremendous potential in the healthcare sector.

[0003] Food-based health supplements typically contain a variety of natural plant extracts or Chinese medicinal herbs, which are rich in nutritional and pharmacological activity. While these products offer numerous advantages, they also face technical challenges in practical application. For example, the complex composition of these ingredients, including a wide variety of active ingredients, makes extracting these ingredients a technical challenge, placing high demands on the selection of raw materials and the determination of preparation processes. Furthermore, the efficacy evaluation of existing health supplements primarily relies on traditional Chinese medicine theory and experience, lacking the support of modern scientific quantitative indicators and experimental data. For example, while the health benefits of certain ingredients may be theoretically valid, their actual efficacy still requires quantitative experimental verification.

[0004] In view of this, the present invention is proposed. Summary of the Invention

[0005] The purpose of the present invention is to provide a health-care product containing papaya as both a medicine and a food and its application, so as to solve the problems existing in the above-mentioned prior art.

[0006] To achieve the above object, the present invention provides the following solutions:

[0007] The present invention provides a health-care product having both medicinal and edible properties, the raw materials of which include the following components in proportions by weight:

[0008] 15-20 parts of papaya extract, 8-10 parts of chicory root extract, 5-6 parts of complex fermentation extract, 5-7 parts of cornus officinalis extract, 3-6 parts of turmeric and 2-3 parts of plantain.

[0009] Furthermore, the preparation method of the papaya extract comprises the following steps:

[0010] enzymatically hydrolyzing papaya with a composite enzyme, centrifuging the obtained enzymatic hydrolysis product, and removing the supernatant to obtain the papaya extract;

[0011] The complex enzyme is a compound mixture of cellulase and pectinase in a mass ratio of 1-2:1-3; the temperature of the enzymatic hydrolysis is 45-50° C., and the time is 2-3 hours.

[0012] Furthermore, the preparation method of the chicory root extract comprises the following steps:

[0013] The dried chicory root is subjected to ethanol reflux extraction, the extract is extracted with petroleum ether, the extract is concentrated and then extracted with ethyl acetate, the ethyl acetate phase is collected and concentrated to obtain the chicory root extract.

[0014] Furthermore, the preparation method of the composite fermentation extract comprises the following steps:

[0015] Pine pollen and galangal are mixed, beta-glucanase is added and fermented to obtain the composite fermentation extract.

[0016] Furthermore, the mass ratio of the pine pollen to the galangal is 1:2-3.

[0017] Furthermore, the fermentation temperature is 38±2° C., and the fermentation time is 3-5 days.

[0018] Furthermore, the preparation method of the Cornus officinalis extract comprises the following steps:

[0019] (1) crushing the dried cornus officinalis pulp, adding a biocomplex enzyme to carry out an enzymatic hydrolysis reaction, and after the enzymatic hydrolysis reaction is completed, inactivating the enzyme to obtain an enzymatic hydrolyzate;

[0020] (2) subjecting the enzymatic hydrolysate obtained in step (1) to ultrasonic-assisted supercritical carbon dioxide extraction to obtain the Cornus officinalis extract.

[0021] Furthermore, the biological composite enzyme is a mixture of cellulase, pectinase and hemicellulase in a mass ratio of 1-2:1-3:1-2.

[0022] Furthermore, the extraction pressure of the ultrasonic-assisted supercritical carbon dioxide extraction is 20-30 MPa, and the temperature is 40-50° C.; the ultrasonic frequency of the ultrasonic-assisted supercritical carbon dioxide extraction is 20-40 kHz; and the CO2 flow rate is 5-10 L / min.

[0023] The raw materials of the present invention all exert their unique pharmacological effects and efficacies and work synergistically to achieve the best health-care effect.

[0024] Papaya (scientific name: Carica papaya) is a tropical fruit rich in various nutrients, including vitamin C, vitamin A, potassium, dietary fiber, and various antioxidants. These ingredients make papaya not only rich in nutritional value but also possess significant health benefits. The present invention extracts active ingredients from papaya and, through rationally formulated ingredients, effectively alleviates joint inflammation and pain while promoting uric acid metabolism and reducing uric acid accumulation in the body. The enzymatic hydrolysis method of the present invention efficiently releases the active ingredients in papaya, ensuring efficient retention of the active ingredients in the extract, enhancing interactions between the components, and achieving health benefits.

[0025] Chicory root has the potential to lower serum uric acid levels, protect the liver, and has anti-inflammatory and antioxidant properties. The present invention uses a combination of ethanol reflux extraction, petroleum ether extraction, and ethyl acetate extraction to fully extract the active ingredients in chicory root, ensuring its anti-inflammatory, analgesic, and immunomodulatory effects.

[0026] The present invention adopts ultrasound-assisted supercritical carbon dioxide extraction combined with enzymatic hydrolysis reaction to extract the effective substances in Cornus officinalis, ensuring that the anti-inflammatory, analgesic and immunoregulatory effects of the active ingredients are best exerted.

[0027] By determining the raw material components and their reasonable proportions, and combining them with scientific preparation methods, the medicinal and edible health care products of the present invention can play an important role in the following aspects:

[0028] a. Lowering uric acid: The papaya extract, chicory root extract, composite fermentation product and plantain of the present invention can synergistically promote uric acid excretion, lower blood uric acid levels, and prevent gout attacks.

[0029] b. Anti-inflammatory and analgesic: The papaya extract, cornus officinalis extract and turmeric of the present invention act synergistically to significantly reduce joint inflammation and pain.

[0030] c. Antioxidant: The antioxidant properties of the various ingredients of the present invention work together to scavenge free radicals, protect cell health, and delay aging.

[0031] d. Regulate metabolism and immunity: Compound fermentation extract and Cornus officinalis extract can further enhance basal immunity and ensure body health by regulating intestinal flora and immune system.

[0032] The present invention also provides a method for preparing the above-mentioned medicine-food health-care product, comprising the following steps:

[0033] The raw materials are mixed according to a mass ratio, a binder is added to prepare a soft material, and then granulated and dried to obtain the medicine and food health product.

[0034] The present invention further provides the use of the above-mentioned medicine-food health-care product in preventing and treating gout, anti-inflammatory and analgesic, and improving immunity.

[0035] The present invention further provides a medicinal and edible composition for treating gout, wherein the raw materials include the following components in the following mass proportions:

[0036] 15-20 parts of papaya extract, 8-10 parts of chicory root extract, 5-6 parts of complex fermentation extract, 5-7 parts of cornus officinalis extract, 3-6 parts of turmeric and 2-3 parts of plantain.

[0037] The present invention discloses the following technical effects:

[0038] The present invention provides a edible and medicinal health product and its application, aiming to address the problems of poor efficacy and single ingredients in existing health products. The raw materials used in the present invention are all natural plant extracts that are both edible and medicinal. This edible and medicinal health product achieves comprehensive health benefits through multiple mechanisms (uric acid reduction, anti-inflammatory and analgesic effects, antioxidant effects, and metabolic and immune regulation). DETAILED DESCRIPTION

[0039] Various exemplary embodiments of the present invention will now be described in detail. This detailed description should not be considered as limiting the present invention, but rather as a more detailed description of certain aspects, features, and embodiments of the present invention.

[0040] It should be understood that the terms described herein are intended only to describe particular embodiments and are not intended to limit the present invention. In addition, for numerical ranges herein, it should be understood that each intermediate value between the upper and lower limits of the range is also specifically disclosed. The intermediate value within any stated value or stated range, and each smaller range between any other stated value or intermediate value within the stated range, is also encompassed within the present invention. The upper and lower limits of these smaller ranges may be independently included or excluded within the scope.

[0041] Unless otherwise indicated, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art. Although only preferred methods and materials are described herein, any methods and materials similar or equivalent to those described herein may also be used in the practice or testing of the present invention. All documents mentioned in this specification are incorporated by reference to disclose and describe the methods and / or materials associated with the documents. In the event of any conflict with any incorporated document, the contents of this specification shall prevail.

[0042] It will be apparent to those skilled in the art that various modifications and variations may be made to the specific embodiments described herein without departing from the scope or spirit of the invention. Other embodiments will be apparent to those skilled in the art from the description of the invention. The description and examples are intended to be illustrative only.

[0043] The words “include,” “including,” “have,” “contain,” etc. used in this document are open-ended terms, meaning including but not limited to.

[0044] Example 1

[0045] The medicinal and edible health product of this embodiment includes the following raw material components in the following proportions by weight:

[0046] 18 parts of papaya extract, 9 parts of chicory root extract, 5 parts of complex fermentation extract, 6 parts of cornus officinalis extract, 4 parts of turmeric and 3 parts of plantain.

[0047] The preparation method of the medicinal and edible health product of this embodiment comprises the following steps:

[0048] Step S1. Preparation of papaya extract:

[0049] (1) Mash the papaya and put it into an enzymolysis tank, then add 60 times the weight of water, heat to 50°C, and then add 0.3% of the weight of the papaya (a mixture of cellulase and pectinase in a mass ratio of 1:3); after adding the complex enzyme, enzymolysis is carried out at 50°C for 2 hours to obtain an enzymolysis product; after the enzymolysis is completed, heat to 90°C to terminate the enzyme activity and prevent excessive decomposition;

[0050] (2) centrifuging the enzymatic hydrolysis product at a centrifugal speed of 20,000 rpm, removing the supernatant after centrifugation, obtaining a centrifuged product, and drying to obtain a papaya extract.

[0051] Step S2. Preparation of chicory root extract:

[0052] (1) The chicory root was dried and crushed, and then subjected to ethanol reflux extraction. The extract was collected and extracted with petroleum ether three times. The petroleum ether phases were combined and concentrated;

[0053] (2) The concentrated solution of step (1) was extracted three times with ethyl acetate, the ethyl acetate extracts were combined, concentrated under vacuum to remove the solvent, and dried to obtain chicory root extract.

[0054] Step S3. Preparation of composite fermentation extract:

[0055] Pine pollen and galangal were compounded in a mass ratio of 1:2, and then β-glucanase was added and fermented at 38±2°C for 3 days to obtain a composite fermentation extract.

[0056] Step S4. Preparation of Cornus officinalis extract:

[0057] (1) Dried cornus officinalis pulp was crushed and a biocomplex enzyme (a mixture of cellulase, pectinase, and hemicellulase in a mass ratio of 2:3:2) was added at 0.3% of the cornus officinalis pulp mass. Enzymatic hydrolysis was carried out at 45°C for 2 h while stirring to ensure sufficient contact between the enzyme and the raw material. After the enzymatic hydrolysis was completed, the mixture was heated to 90°C to terminate the enzyme activity and prevent excessive decomposition.

[0058] (2) Concentrating and drying the enzymatic hydrolyzate;

[0059] (3) The enzymatic hydrolysis product obtained in step (2) is placed in a supercritical carbon dioxide extraction device and equipped with an ultrasonic generator for supercritical carbon dioxide extraction. The extraction pressure is set to 25 MPa, the temperature is 45° C., the CO2 flow rate is 8 L / min, and ultrasonic assistance (frequency 30 kHz) is turned on at the same time. The product is treated for 1.5 hours and freeze-dried to obtain the Cornus officinalis extract.

[0060] Step S5. Preparation of food-drug health-care products

[0061] (1) Place the above raw materials in a mixer according to the mass ratio and stir for 10 minutes to ensure that all ingredients are mixed evenly;

[0062] (2) adding dextrin as an adhesive to the mixed powder of step (1) to prepare a soft material;

[0063] (3) using an extrusion spheronization machine to form granules;

[0064] (4) Drying the granules in a drying oven at 50° C. until the moisture content reaches 5%, thereby obtaining a medicinal and edible health product.

[0065] Example 2

[0066] The medicinal and edible health product of this embodiment includes the following raw material components in the following proportions by weight:

[0067] 15 parts of papaya extract, 10 parts of chicory root extract, 5 parts of complex fermentation extract, 5 parts of cornus officinalis extract, 3 parts of turmeric and 3 parts of plantain.

[0068] The preparation method of the medicinal and edible health product of this embodiment comprises the following steps:

[0069] Step S1. Preparation of papaya extract:

[0070] (1) Mash the papaya and put it into an enzymolysis tank, then add 50 times the weight of water, heat to 45°C, and then add 0.3% of the weight of the papaya (a mixture of cellulase and pectinase in a mass ratio of 2:3); after adding the complex enzyme, enzymolysis is carried out at 45°C for 2 hours to obtain an enzymolysis product; after the enzymolysis is completed, heat to 90°C to terminate the enzyme activity and prevent excessive decomposition;

[0071] (2) centrifuging the enzymatic hydrolysis product at a centrifugal speed of 20,000 rpm, removing the supernatant after centrifugation, obtaining a centrifuged product, and drying to obtain a papaya extract.

[0072] Step S2. Preparation of chicory root extract:

[0073] (1) The chicory root was dried and crushed, and then subjected to ethanol reflux extraction. The extract was collected and extracted with petroleum ether three times. The petroleum ether phases were combined and concentrated;

[0074] (2) The concentrated solution of step (1) was extracted three times with ethyl acetate, the ethyl acetate extracts were combined, and the solvent was removed by vacuum concentration to obtain chicory root extract.

[0075] Step S3. Preparation of composite fermentation extract:

[0076] Pine pollen and galangal were compounded in a mass ratio of 1:2, and then β-glucanase was added and fermented at 38±2°C for 5 days to obtain a composite fermentation extract.

[0077] Step S4. Preparation of Cornus officinalis extract:

[0078] (1) Dried cornus officinalis pulp was crushed and a biocomplex enzyme (a mixture of cellulase, pectinase, and hemicellulase in a mass ratio of 2:1:1) was added at 0.2% of the cornus officinalis pulp mass. Enzymatic hydrolysis was carried out at 45°C for 2 h while stirring to ensure sufficient contact between the enzyme and the raw material. After the enzymatic hydrolysis was completed, the mixture was heated to 90°C to terminate the enzyme activity and prevent excessive decomposition.

[0079] (2) Concentrating and drying the enzymatic hydrolyzate;

[0080] (3) placing the enzymatic hydrolysis product obtained in step (2) in a supercritical carbon dioxide extraction device and equipping it with an ultrasonic generator for supercritical carbon dioxide extraction, setting the extraction pressure to 20 MPa, the temperature to 40° C., the CO2 flow rate to 10 L / min, and simultaneously turning on ultrasonic assistance (frequency 35 kHz), treating for 2 hours, and freeze-drying to obtain the Cornus officinalis extract.

[0081] Step S5. Preparation of food-drug health-care products

[0082] (1) Place the above raw materials in a mixer according to the mass ratio and stir for 15 minutes to ensure that all ingredients are mixed evenly;

[0083] (2) adding adhesive starch to the mixed powder of step (1) to prepare a soft material;

[0084] (3) using an extrusion spheronization machine to form granules;

[0085] (4) Drying the granules in a drying oven at 50° C. until the moisture content reaches 5%, thereby obtaining a medicinal and edible health product.

[0086] Example 3

[0087] The medicinal and edible health product of this embodiment includes the following raw material components in the following proportions by weight:

[0088] 15 parts of papaya extract, 8 parts of chicory root extract, 5 parts of complex fermentation extract, 7 parts of cornus officinalis extract, 4 parts of turmeric and 2 parts of plantain.

[0089] The preparation method of the medicinal and edible health product of this embodiment comprises the following steps:

[0090] Step S1. Preparation of papaya extract:

[0091] (1) Mash the papaya and put it into an enzymolysis tank, then add 50 times the weight of water, heat to 45°C, and then add 0.3% of the weight of the papaya (a mixture of cellulase and pectinase in a mass ratio of 1:1); after adding the complex enzyme, enzymolysis is carried out at 50°C for 2 hours to obtain an enzymolysis product; after the enzymolysis is completed, heat to 90°C to terminate the enzyme activity and prevent excessive decomposition;

[0092] (2) centrifuging the enzymatic hydrolysis product at a centrifugal speed of 20,000 rpm, removing the supernatant after centrifugation, obtaining a centrifuged product, and drying to obtain a papaya extract.

[0093] Step S2. Preparation of chicory root extract:

[0094] (1) The chicory root was dried and crushed, and then subjected to ethanol reflux extraction. The extract was collected and extracted with petroleum ether three times. The petroleum ether phases were combined and concentrated;

[0095] (2) The concentrated solution of step (1) was extracted three times with ethyl acetate, the ethyl acetate extracts were combined, and the solvent was removed by vacuum concentration to obtain chicory root extract.

[0096] Step S3. Preparation of composite fermentation extract:

[0097] Pine pollen and galangal were compounded in a mass ratio of 1:2, and then β-glucanase was added and fermented at 38±2°C for 5 days to obtain a composite fermentation extract.

[0098] Step S4. Preparation of Cornus officinalis extract:

[0099] (1) Dried cornus officinalis pulp was crushed and a biocomplex enzyme (a mixture of cellulase, pectinase, and hemicellulase in a mass ratio of 2:1:1) was added at 0.2% of the cornus officinalis pulp mass. Enzymatic hydrolysis was carried out at 45°C for 2 h while stirring to ensure sufficient contact between the enzyme and the raw material. After the enzymatic hydrolysis was completed, the mixture was heated to 90°C to terminate the enzyme activity and prevent excessive decomposition.

[0100] (2) Concentrating and drying the enzymatic hydrolyzate;

[0101] (3) placing the enzymatic hydrolysis product obtained in step (2) in a supercritical carbon dioxide extraction device and equipping it with an ultrasonic generator for supercritical carbon dioxide extraction, setting the extraction pressure to 25 MPa, the temperature to 45° C., the CO2 flow rate to 8 L / min, and simultaneously turning on ultrasonic assistance (frequency 35 kHz), treating for 2 hours, and freeze-drying to obtain the Cornus officinalis extract.

[0102] Step S5. Preparation of food-drug health-care products

[0103] (1) Place the above raw materials in a mixer according to the mass ratio and stir for 15 minutes to ensure that all ingredients are mixed evenly;

[0104] (2) adding a binder such as dextrin to the mixed powder of step (1) to prepare a soft material;

[0105] (3) using an extrusion spheronization machine to form granules;

[0106] (4) Drying the granules in a drying oven at 50° C. until the moisture content is 5%, thereby obtaining a medicinal and edible health product.

[0107] Comparative Example 1

[0108] The only difference from Example 1 is that the papaya extract is replaced by an equal mass of dry papaya powder.

[0109] Comparative Example 2

[0110] The only difference from Example 1 is that step S4 is used to extract the chicory root extract.

[0111] Comparative Example 3

[0112] The only difference from Example 1 is that the chicory root extract is replaced by an equal mass of dried chicory root.

[0113] Comparative Example 4

[0114] The only difference from Example 1 is that the mass parts of the papaya extract were adjusted to 25 parts.

[0115] Effect Verification Example 1

[0116] 1. Experimental Subjects

[0117] Sample selection: 240 patients with mild to moderate gout, aged 45-65 years, were selected.

[0118] Experimental grouping: The patients were randomly divided into 8 groups, 30 people in each group. There was no significant difference in the condition and age of the groups, and they were respectively designated as experimental groups 1-7 and control groups; among them, the patients in experimental groups 1-3 took the medicinal and edible health products of Examples 1-3, respectively, and the patients in experimental groups 4-7 took the medicinal and edible health products of Comparative Examples 1-4, respectively.

[0119] The patients in experimental groups 1-7 took 2 tablets of the food-medicine-sustainable health product (0.5 g / tablet, the raw materials of the food-medicine-sustainable health product accounted for 50%), 3 times a day.

[0120] Control group: Take the same dose of placebo (same appearance as the experimental group but without active ingredients) daily, 2 tablets each time, 3 times a day.

[0121] 2. Experimental cycle

[0122] Observation period: 12 weeks, with follow-up records conducted weekly.

[0123] 3. Evaluation Metrics

[0124] a. Pain score: The visual analogue scale (VAS) was used to assess joint pain severity, ranging from 0 to 10 (0 = no pain, 10 = the most painful). The mean pain scores for each group after 12 weeks are shown in Table 1.

[0125] Table 1

[0126]

[0127]

[0128] The joint pain of the patients in experimental groups 1-3 who took the medicinal and edible health products of Examples 1-3 of the present invention was significantly alleviated, and the pain scores dropped significantly.

[0129] b. Joint function: The Health Assessment Questionnaire (HAQ) was used to assess patients' ability to perform daily activities. The mean joint function scores for each group after 12 weeks are shown in Table 2.

[0130] Table 2

[0131] 0d(minutes) 12 weeks later (minutes) Experimental Group 1 1.8 0.8 Experimental Group 2 1.7 0.8 Experimental Group 3 1.8 0.7 Experimental Group 4 1.7 1.2 Experimental Group 5 1.8 1.4 Experimental Group 6 1.8 1.2 Experimental Group 7 1.7 1.3 control group 1.7 1.5

[0132] The HAQ scores of the patients in experimental groups 1-3 who took the medicinal and edible health products of Examples 1-3 of the present invention decreased significantly, indicating that joint function was significantly improved; the health products of the present invention not only relieved pain, but also promoted the recovery of joint function.

[0133] c. Inflammatory markers: Serum C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were measured as inflammatory markers. The average values ​​of the measurement results after 12 weeks are shown in Table 3.

[0134] Table 3

[0135]

[0136]

[0137] The CRP levels and ESR of the experimental groups 1-3 taking the medicinal and edible health products of Examples 1-3 of the present invention decreased significantly, indicating that the inflammatory indicators were significantly improved.

[0138] d. Quality of Life: The SF-36 quality of life questionnaire was used to assess patients' quality of life. The mean quality of life scores for each group after 12 weeks are shown in Table 4.

[0139] Table 4

[0140] 0d(minutes) 12 weeks later (minutes) Experimental Group 1 44 72 Experimental Group 2 43 71 Experimental Group 3 45 72 Experimental Group 4 43 61 Experimental Group 5 44 56 Experimental Group 6 44 57 Experimental Group 7 45 57 control group 43 48

[0141] As can be seen in Table 4, after the patients’ pain was relieved and joint function improved, their overall quality of life and mental health also improved.

[0142] e. Serum uric acid concentration: The mean serum uric acid concentration of each group of patients was monitored. The mean serum uric acid concentration of each group of patients after 12 weeks is shown in Table 5.

[0143] Table 5

[0144]

[0145]

[0146] Effect Verification Example 2

[0147] Experimental subjects: Healthy adult mice were selected as experimental subjects and divided into an experimental group (taking the medicinal and edible health care product of Example 1) and a control group (not taking the health care product), with 20 mice in each group.

[0148] Administration: The experimental group mice were given the above-mentioned medicinal and edible health products by gavage for 30 consecutive days. The dosage was converted to 50 mg / kg body weight per day based on the human equivalent dose.

[0149] After the experiment, the immunoglobulin levels of mice in different groups were measured as shown in Table 1:

[0150] Table 6

[0151]

[0152] The results showed that the IgG, IgA and IgM levels in the serum of the experimental group of mice were significantly higher than those in the control group.

[0153] The above data show that the immunoglobulin levels of the mice in the experimental group taking the food-drug health product of the present invention were significantly improved, indicating that the health product can promote the production of immunoglobulins and enhance the body's immune function.

[0154] The embodiments described above are merely descriptions of preferred embodiments of the present invention and are not intended to limit the scope of the present invention. Without departing from the spirit of the present invention, various modifications and improvements made to the technical solutions of the present invention by persons skilled in the art should fall within the scope of protection defined by the claims of the present invention.

Claims

1. A health-care product that is both a medicine and a food, characterized in that: The raw materials include the following components in the following mass proportions: 15-20 parts of papaya extract, 8-10 parts of chicory root extract, 5-6 parts of complex fermentation extract, 5-7 parts of cornus officinalis extract, 3-6 parts of turmeric, and 2-3 parts of plantain; The preparation method of the papaya extract comprises the following steps: enzymatically hydrolyzing papaya with a composite enzyme, centrifuging the obtained enzymatic hydrolysis product, removing the supernatant, and drying to obtain the papaya extract; The complex enzyme is a mixture of cellulase and pectinase in a mass ratio of 1-2:1-3; the enzymatic hydrolysis temperature is 45-50°C and the time is 2-3h; The preparation method of the chicory root extract comprises the following steps: The dried chicory root is subjected to ethanol reflux extraction, the extract is extracted with petroleum ether, the extract is concentrated and then extracted with ethyl acetate, the ethyl acetate phase is collected, concentrated, and dried to obtain the chicory root extract; The preparation method of the composite fermentation extract comprises the following steps: Mixing pine pollen and galangal, adding β-glucanase and fermenting to obtain the composite fermentation extract; The mass ratio of pine pollen to galangal is 1:2-3; the fermentation temperature is 38±2° C., and the fermentation time is 3-5 days; The preparation method of the Cornus officinalis extract comprises the following steps: (1) crushing the dried cornus officinalis pulp, adding a biocomplex enzyme to carry out an enzymatic hydrolysis reaction, and after the enzymatic hydrolysis reaction is completed, inactivating the enzyme to obtain an enzymatic hydrolyzate; (2) subjecting the enzymatic hydrolyzate obtained in step (1) to ultrasonic-assisted supercritical carbon dioxide extraction, and freeze-drying to obtain the Cornus officinalis extract; The biological composite enzyme is a mixture of cellulase, pectinase and hemicellulase in a mass ratio of 1-2:1-3:1-2.

2. The medicine-food health product according to claim 1, characterized in that: The extraction pressure of the ultrasonic-assisted supercritical carbon dioxide extraction is 20-30 MPa, and the temperature is 40-50° C.; the ultrasonic frequency of the ultrasonic-assisted supercritical carbon dioxide extraction is 20-40 kHz.

3. The method for preparing the edible and medicinal health product according to any one of claims 1 to 2, characterized in that: The following steps are involved: The raw materials are mixed according to a mass ratio, a binder is added to prepare a soft material, and then granulated and dried to obtain the medicine and food health product.

Images