Bacteriostatic itching-relieving mosquito-repelling essence and preparation method thereof

Abstract

The invention provides antibacterial, itching-relieving and mosquito-repelling essence and a preparation method thereof, and belongs to the technical field of mosquito-repelling compositions. The antibacterial, itching-relieving and mosquito-repelling essence is prepared from the following components in percentage by weight: 0.1 to 0.5 percent of allantoin, 25 to 36 percent of alcohol solvent, 0.05 to 0.3 percent of menthol, 0.05 to 0.3 percent of borneol, 0.05 to 0.3 percent of menthol, 1 to 3 percent of ethyl butylacetamidopropionate, 0.05 to 1.5 percent of plant extract, 0.5 to 2 percent of surfactant, 0.5 to 1.5 percent of preservative and the balance of water. In the implementation process, it is found that by controlling the mass ratio of the surfactant to the ethyl butylacetaminopropionate to the plant extract, the durability of the mosquito-repelling effect can be effectively improved, the action time of the mosquito-repelling essence is prolonged, the antibacterial performance of the essence can be improved, and the antibacterial and itching-relieving effects are obviously improved.

Description

Technical Field

[0001] The invention belongs to the technical field of mosquito repellent compositions, and in particular relates to an antibacterial and antipruritic mosquito repellent essence and a preparation method thereof. Background Art

[0002] The harm of mosquitoes is well known. After being bitten by mosquitoes, it is not only painful and itchy, but more seriously, mosquitoes can spread diseases such as malaria, filariasis, epidemic encephalitis B and dengue fever. Therefore, a good anti-mosquito and insect repellent product is particularly important. Because mosquitoes mainly target human odor, such as exhaled carbon dioxide or volatile substances on the body surface, and mosquito repellent sprays a barrier on the body. This barrier interferes with the chemical sensors of mosquito antennae to sense volatile substances on the human body surface, thereby preventing people from being bitten by mosquitoes.

[0003] There are four common mosquito repellents: DEET, oil of lemon eucalyptus, icaridin and immonim. DEET is a widely used insecticide that is sprayed on the skin or clothes to prevent mosquito bites by blocking the 1-octen-3-ol of the insect olfactory receptors. However, because it is highly irritating to the skin, DEET cannot be used directly in contact with the skin. Oil of lemon eucalyptus is an extract of the Australian eucalyptus tree. Research results show that the maximum protection time of lemon eucalyptus oil against mosquitoes is shorter than that of DEET. Children under 3 years old are usually prohibited from using mosquito repellents containing lemon eucalyptus oil. Icaridin, also known as hydroxyphenoxylate, its single or compound preparations will not cause damage to common home decoration materials, including plastics, coatings, metal decorative foils and paints, and its effectiveness is better than DEET. Immonim, also known as chlorpyrifos, is a broad-spectrum, highly effective insect repellent that has a good repellent effect on mosquitoes, flies, lice, etc., has a long repellent effect, and can be used under different climatic conditions. Using certain plants that emit special smells to repel mosquitoes has a long history, which is recorded in documents such as "The Book of Songs". The significant advantage of plant mosquito repellents is that they are green, safe and harmless to the human body. However, the existing plant mosquito repellents have a short effective duration.

[0004] For example, Chinese patent CN109511688A discloses a woody anti-mosquito and insect repellent compound essential oil, the raw materials include plant compound extracts and solvents, the plant compound extracts are a mixture of wormwood leaf extracts, grapefruit flower extracts, orange flower extracts, mosquito repellent grass extracts, mint extracts, jasmine extracts, geranium extracts, lavender extracts, carnivorous grass extracts, pitcher plant extracts and walnut leaf extracts, and the extracts are a mixture of petroleum ether extracts and ethanol extracts at a mass ratio of 1:0.5. The woody anti-mosquito and insect repellent compound essential oil of the invention does not contain chemical insecticide components and preservatives, and the components are all plant raw materials, which are environmentally friendly and pollution-free, have significant mosquito repellent effects, can also remove odors, leave a fresh fragrance, can be carried out for use, can also be placed for use, and are not restricted in use. At the same time, the smell is fragrant, and the environmental air quality can be improved while repelling mosquitoes. However, the antibacterial and antipruritic effects of the woody anti-mosquito and insect repellent compound essential oil are not ideal.

[0005] Therefore, there is an urgent need to develop a mosquito repellent essence with good mosquito repellent effect, long duration, and good antipruritic and antibacterial effects and a preparation method thereof. Summary of the invention

[0006] In order to achieve the above purpose, the present invention adopts the following technical solutions:

[0007] In one aspect, the present invention provides an antibacterial, antipruritic and mosquito repellent essence, which comprises the following components by weight percentage:

[0008] Allantoin 0.1-0.5%, alcohol solvent 25-36%, menthol 0.05-0.3%, borneol 0.05-0.3%, menthyl glycol 0.05-0.3%, ethyl butyl acetylaminopropionate 1-3%, plant extract 0.05-1.5%, surfactant 0.5-2%, preservative 0.5-1.5% and water as the balance.

[0009] Preferably, the antibacterial, antipruritic and mosquito repellent essence comprises the following components by weight percentage:

[0010] Allantoin 0.2-0.4%, alcohol solvent 28-32%, menthol 0.1-0.2%, borneol 0.1-0.2%, menthyl glycol 0.1-0.2%, ethyl butyl acetylaminopropionate 1.5-2.5%, plant extract 0.5-1.2%, surfactant 1-2%, preservative 0.8-1.2% and water as the balance.

[0011] in,

[0012] The alcohol solvent is a mixture of propylene glycol and ethanol, and the mass ratio of the two is 1:1-3; preferably 1:2.

[0013] The plant extract is a mixture of geranium oil, peony extract and wormwood extract; the mass ratio of the three is 1-3:1:1-2; preferably 3:1:2.

[0014] During the implementation of the present invention, it is found that the use of plant extracts mixed with ethyl butyl acetylaminopropionate and menthyl glycol can effectively repel mosquitoes, significantly improve the mosquito repellent effect of the product, and have good antipruritic and antibacterial effects.

[0015] The surfactant is a mixture of PEG-40 hydrogenated castor oil and polyoxyethylene alkylphenol ether, and the mass ratio of the two is 3-5:1.

[0016] The present invention adds a surfactant to the components and unexpectedly finds that by controlling the mass ratio of the surfactant, ethyl butyl acetylaminopropionate and the plant extract, not only the durability of the mosquito repellent effect can be effectively improved and the action time of the mosquito repellent essence can be extended, but also the antibacterial performance of the essence can be improved, so that the antibacterial and antipruritic effects are significantly improved.

[0017] As some preferred implementation schemes, the mass ratio of the surfactant, ethyl butyl acetylaminopropionate and the plant extract is 1-2:1.5-2.5:0.5-1.2; preferably 1.5:2:1.

[0018] The preservative is a composite preservative of ethylhexylglycerin, caprylhydroxamic acid, 1,3-propylene glycol and 1,2-hexanediol, purchased from Guangzhou Northern Lights Biotechnology Co., Ltd., model: LC1840.

[0019] The present invention also provides a method for preparing the antibacterial, antipruritic and mosquito repellent essence, comprising the following steps:

[0020] (1) Heat water to 85° C., add allantoin and propylene glycol, and stir until uniform to obtain a mixture A, which is set aside;

[0021] (2) mixing borneol, menthol, ethyl butyl acetylaminopropionate and ethanol, stirring until uniform, then adding to mixture A, and continuing to stir until uniform while keeping warm, to obtain mixture B;

[0022] (3) mixing menthyl glycol, plant extract and surfactant evenly and adding them to mixture B, cooling to 65° C., maintaining the temperature and stirring evenly to obtain mixture C;

[0023] (4) Add the preservative to the mixture C and stir evenly, then cool to room temperature to obtain the antibacterial, antipruritic and mosquito repellent essence.

[0024] Compared with the prior art, the present invention has the following beneficial effects:

[0025] (1) Plant extracts are natural ingredients with high safety. The present invention uses a mixture of geranium oil, peony extract and wormwood extract as one of the effective ingredients of the mosquito repellent essence, which not only has a mosquito repellent effect, but also has a good antibacterial and antipruritic effect. Among them, geranium oil has an insecticidal effect, and peony extract has an inhibitory effect on a variety of bacteria and fungi, which can help prevent and treat skin infections; wormwood extract has an inhibitory effect on nuclear factor receptor activation and has a good antibacterial effect. During the implementation of the present invention, a mixture of geranium oil, peony extract and wormwood extract is used as a plant extract, and the mass ratio of the three is controlled to be 1-3:1:1-2. The three ingredients complement each other, which can not only improve the mosquito repellent effect of the essence, but also have an antibacterial and antipruritic effect.

[0026] (2) The present invention adds a surfactant to the components. It is unexpectedly found that by controlling the mass ratio of the surfactant, ethyl butyl acetylaminopropionate and the plant extract to be 1-2:1.5-2.5:0.5-1.2, not only the durability of the mosquito repellent effect can be effectively improved and the action time of the mosquito repellent essence can be extended, but also the antibacterial performance of the essence can be improved, so that the antibacterial and antipruritic effects are significantly improved. DETAILED DESCRIPTION

[0027] The following will be combined with the tables in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0028] Hereinafter, examples and comparative examples of the present invention will be shown to explain the composition of the present invention in more detail, but the present invention is not limited thereto.

[0029] The present invention does not limit the sources of the raw materials used. Unless otherwise specified, the raw materials used in the present invention are all common commercial products in the technical field, and the plant extracts used are all purchased from Xi'an Beijinuo Biotechnology Co., Ltd.

[0030] Example 1: An antibacterial, antipruritic and mosquito repellent essence and its preparation method

[0031] The composition includes the following components by weight percentage:

[0032] Allantoin 0.1%, alcohol solvent 25%, menthol 0.05%, borneol 0.05%, menthyl glycol 0.05%, ethyl butyl acetylaminopropionate 1%, plant extract 0.05%, surfactant 0.5%, preservative 0.5% and water as the balance.

[0033] The alcohol solvent is a mixture of propylene glycol and ethanol, and the mass ratio of the two is 1:1;

[0034] The plant extract is a mixture of geranium oil, peony extract and wormwood extract; the mass ratio of the three is 1:1:1;

[0035] The surfactant is a mixture of PEG-40 hydrogenated castor oil and polyoxyethylene alkylphenol ether, and the mass ratio of the two is 3:1.

[0036] The preservative is a composite preservative of ethylhexylglycerin, caprylhydroxamic acid, 1,3-propylene glycol and 1,2-hexanediol, and the model is LC1840.

[0037] The preparation method comprises the following steps:

[0038] (1) Heat water to 85° C., add allantoin and propylene glycol, and stir until uniform to obtain a mixture A, which is set aside;

[0039] (2) mixing borneol, menthol, ethyl butyl acetylaminopropionate and ethanol, stirring until uniform, then adding to mixture A, and continuing to stir until uniform while keeping warm, to obtain mixture B;

[0040] (3) mixing menthyl glycol, plant extract and surfactant evenly and adding them to mixture B, cooling to 65° C., maintaining the temperature and stirring evenly to obtain mixture C;

[0041] (4) Add the preservative to the mixture C and stir evenly, then cool to room temperature to obtain the antibacterial, antipruritic and mosquito repellent essence.

[0042] Example 2: An antibacterial, antipruritic and mosquito repellent essence and its preparation method

[0043] The composition includes the following components by weight percentage:

[0044] Allantoin 0.5%, alcohol solvent 36%, menthol 0.3%, borneol 0.3%, menthyl glycol 0.3%, ethyl butyl acetylaminopropionate 3%, plant extract 1.5%, surfactant 1.8%, preservative 1.5% and water as the balance.

[0045] The alcohol solvent is a mixture of propylene glycol and ethanol, and the mass ratio of the two is 1:3;

[0046] The plant extract is a mixture of geranium oil, peony extract and wormwood extract; the mass ratio of the three is 3:1:1;

[0047] The surfactant is a mixture of PEG-40 hydrogenated castor oil and polyoxyethylene alkylphenol ether, and the mass ratio of the two is 5:1.

[0048] The preservative is a compound preservative of ethylhexylglycerin, caprylhydroxamic acid, 1,3-propylene glycol and 1,2-hexanediol, and the preservative model is: LC1840.

[0049] The preparation method comprises the following steps:

[0050] (1) Heat water to 85° C., add allantoin and propylene glycol, and stir until uniform to obtain a mixture A, which is set aside;

[0051] (2) mixing borneol, menthol, ethyl butyl acetylaminopropionate and ethanol, stirring until uniform, then adding to mixture A, and continuing to stir until uniform while keeping warm, to obtain mixture B;

[0052] (3) mixing menthyl glycol, plant extract and surfactant evenly and adding them to mixture B, cooling to 65° C., maintaining the temperature and stirring evenly to obtain mixture C;

[0053] (4) Add the preservative to the mixture C and stir evenly, then cool to room temperature to obtain the antibacterial, antipruritic and mosquito repellent essence.

[0054] Example 3: An antibacterial, antipruritic and mosquito repellent essence and its preparation method

[0055] The composition includes the following components by weight percentage:

[0056] Allantoin 0.2%, alcohol solvent 32%, menthol 0.2%, borneol 0.1%, menthyl glycol 0.1%, ethyl butyl acetylaminopropionate 2.5%, plant extract 0.5%, surfactant 2%, preservative 0.8% and water as the balance.

[0057] The alcohol solvent is a mixture of propylene glycol and ethanol, and the mass ratio of the two is 1:1.5;

[0058] The plant extract is a mixture of geranium oil, peony extract and wormwood extract; the mass ratio of the three is 2:1:2;

[0059] The surfactant is a mixture of PEG-40 hydrogenated castor oil and polyoxyethylene alkylphenol ether, and the mass ratio of the two is 4:1.

[0060] The preservative is a compound preservative of ethylhexylglycerin, caprylhydroxamic acid, 1,3-propylene glycol and 1,2-hexanediol, and the preservative model is: LC1840.

[0061] The preparation method comprises the following steps:

[0062] (1) Heat water to 85° C., add allantoin and propylene glycol, and stir until uniform to obtain a mixture A, which is set aside;

[0063] (2) mixing borneol, menthol, ethyl butyl acetylaminopropionate and ethanol, stirring until uniform, then adding to mixture A, and continuing to stir until uniform while keeping warm, to obtain mixture B;

[0064] (3) mixing menthyl glycol, plant extract and surfactant evenly and adding them to mixture B, cooling to 65° C., maintaining the temperature and stirring evenly to obtain mixture C;

[0065] (4) Add the preservative to the mixture C and stir evenly, then cool to room temperature to obtain the antibacterial, antipruritic and mosquito repellent essence.

[0066] Example 4: An antibacterial, antipruritic and mosquito repellent essence and its preparation method

[0067] The composition includes the following components by weight percentage:

[0068] Allantoin 0.3%, alcohol solvent 30%, menthol 0.15%, borneol 0.15%, menthyl glycol 0.15%, ethyl butyl acetylaminopropionate 2.0%, plant extract 1.0%, surfactant 1.5%, preservative 1.0% and water as the balance.

[0069] The alcohol solvent is a mixture of propylene glycol and ethanol, and the mass ratio of the two is 1:2;

[0070] The plant extract is a mixture of geranium oil, peony extract and wormwood extract; the mass ratio of the three is 3:1:2;

[0071] The surfactant is a mixture of PEG-40 hydrogenated castor oil and polyoxyethylene alkylphenol ether, with a mass ratio of 4:1;

[0072] The preservative is a composite preservative of ethylhexylglycerin, caprylhydroxamic acid, 1,3-propylene glycol and 1,2-hexanediol, and the model is LC1840.

[0073] The preparation method comprises the following steps:

[0074] (1) Heat water to 85° C., add allantoin and propylene glycol, and stir until uniform to obtain a mixture A, which is set aside;

[0075] (2) mixing borneol, menthol, ethyl butyl acetylaminopropionate and ethanol, stirring until uniform, then adding to mixture A, and continuing to stir until uniform while keeping warm, to obtain mixture B;

[0076] (3) mixing menthyl glycol, plant extract and surfactant evenly and adding them to mixture B, cooling to 65° C., maintaining the temperature and stirring evenly to obtain mixture C;

[0077] (4) Add the preservative to the mixture C and stir evenly, then cool to room temperature to obtain the antibacterial, antipruritic and mosquito repellent essence.

[0078] Comparative Example 1

[0079] Compared with Example 4, the only difference is that only geranium oil is added as the plant extract. The other parts are the same as Example 4.

[0080] Comparative Example 2

[0081] Compared with Example 4, the only difference is that the peony extract is replaced by the lavender extract. The rest is the same as Example 4.

[0082] Comparative Example 3

[0083] Compared with Example 4, the only difference is that the mass ratio of surfactant, ethyl butyl acetylaminopropionate and plant extract is 1.5:0.5:2, that is, 1.5% surfactant, 0.5% ethyl butyl acetylaminopropionate and 2% plant extract. The rest is the same as Example 4.

[0084] Comparative Example 4

[0085] Compared with Example 4, the only difference is that the mass ratio of surfactant, ethyl butyl acetylaminopropionate and plant extract is 0.4:3.5:0.6, that is, 0.4% surfactant, 3.5% ethyl butyl acetylaminopropionate and 0.6% plant extract. Others are the same as Example 4.

[0086] Comparative Example 5

[0087] Compared with Example 4, the only difference is that the surfactant is only PEG-40 hydrogenated castor oil. Others are the same as Example 4.

[0088] Effect experiment:

[0089] 1. Mosquito repellent durability test

[0090] The test was conducted in accordance with the scheme in Part 9: Repellents, National Standard GB / T13917.9-2009 Indoor Efficacy Test and Evaluation of Public Health Insecticides for Pesticide Registration.

[0091] 45 people with qualified attack power were selected and randomly divided into 9 groups. A 50 mm × 50 mm skin area was drawn on the back of each person's hands. One hand was used as a blank control, and the other hand was smeared with the essence prepared in Examples 1-4 and Comparative Examples 1-5 at a dosage of 1.5 μl / cm 2, expose 40mm×40mm of the skin and cover the rest. 3 hours after applying the mosquito repellent, put your hand into the mosquito cage for 2 minutes to observe whether there are mosquitoes coming to suck blood. Test it once every hour and record the landing of mosquitoes. As long as one mosquito comes to suck blood, the essence is judged to be ineffective. Record the effective protection time of the essence, and take the average value of the effective protection time. The test results are shown in Table 1 below.

[0092] Table 1

[0093]

[0094]

[0095] According to the test results in Table 1 above, the antibacterial and antipruritic mosquito repellent essences prepared in Examples 1-4 of the present invention have good mosquito repellent effects, and the effective protection time of mosquito repellent is more than 8 hours, while changing the type of plant extract in Comparative Examples 1-2 has little effect on the mosquito repellent durability of the essence; while changing the mass ratio of surfactant, ethyl butyl acetylaminopropionate and plant extract or changing the type of surfactant in Comparative Examples 3-5 will significantly affect the mosquito repellent durability of the mosquito repellent essence, and significantly reduce the effective protection time.

[0096] 2. Antibacterial effect detection

[0097] The antibacterial properties of the essences prepared in Examples 1-4 and Comparative Examples 1-5 were investigated.

[0098] The specific evaluation methods are:

[0099] (1) Use PBS buffer to prepare a 10 4 CFU / mL suspensions of Escherichia coli (ATCC25922) and Staphylococcus aureus (ATCC6538);

[0100] (2) Add 100 μL of the Escherichia coli and Staphylococcus aureus suspensions in (1) to the center of the LB solid plate and the Baird-Parker solid plate, respectively, and spread evenly;

[0101] (3) In a sterile environment, use tweezers to spread a 6 mm diameter filter paper on a solid plate, and respectively absorb 10 μL of the essence prepared in Examples 1-4 and Comparative Examples 1-5 and drop it onto the 6 mm filter paper. Each Example or Comparative Example corresponds to one plate, and three positions are set on one plate, and each position corresponds to one filter paper.

[0102] (4) Place the bacteria-containing plate with the filter paper upside down in a 37°C constant temperature incubator and culture for 24 hours;

[0103] (5) After taking out, the diameter of the antibacterial zone of the filter paper was measured using a vernier caliper, the average value was calculated, and the difference in antibacterial performance was calculated, the difference in antibacterial performance = the diameter of the antibacterial zone of each embodiment or comparative example / the diameter of the antibacterial zone of Example 4. The antibacterial performance of each embodiment and the comparative example was compared using the difference in antibacterial performance.

[0104] The calculation results are shown in Table 2 below.

[0105] Table 2

[0106]

[0107]

[0108] According to the test results in Table 2 above, the antibacterial, antipruritic and mosquito repellent essences prepared in Examples 1-4 of the present invention have good antibacterial effects, and the antibacterial effects can reach more than 90%. In Comparative Examples 1-2, changing the type of plant extract has a significant effect on the antibacterial properties of the essence; and in Comparative Examples 3-5, changing the mass ratio of surfactant, ethyl butylacetylaminopropionate and plant extract or changing the type of surfactant significantly affects the antibacterial properties of the mosquito repellent essence, indicating that the mass ratio of surfactant, ethyl butylacetylaminopropionate and plant extract can not only effectively improve the durability of the mosquito repellent effect, prolong the action time of the mosquito repellent essence, but also improve the antibacterial performance of the essence, so that the antibacterial and antipruritic effects are significantly improved.

[0109] Finally, it should be noted that the above content is only used to illustrate the technical solution of the present invention, rather than to limit the scope of protection of the present invention. Simple modifications or equivalent substitutions of the technical solution of the present invention by ordinary technicians in this field do not deviate from the essence and scope of the technical solution of the present invention.

Claims

1. An antibacterial, antipruritic and mosquito repellent essence, characterized in that: The composition includes the following components by weight percentage: Allantoin 0.1-0.5%, alcohol solvent 25-36%, menthol 0.05-0.3%, borneol 0.05-0.3%, menthyl glycol 0.05-0.3%, ethyl butyl acetylaminopropionate 1-3%, plant extract 0.05-1.5%, surfactant 0.5-2%, preservative 0.5-1.5% and water as the balance; The plant extract is a mixture of geranium oil, peony extract and wormwood extract; The surfactant is selected from a mixture of PEG-40 hydrogenated castor oil and polyoxyethylene alkylphenol ether.

2. The antibacterial, antipruritic and mosquito repellent essence according to claim 1, characterized in that: The composition includes the following components by weight percentage: Allantoin 0.2-0.4%, alcohol solvent 28-32%, menthol 0.1-0.2%, borneol 0.1-0.2%, menthyl glycol 0.1-0.2%, ethyl butyl acetylaminopropionate 1.5-2.5%, plant extract 0.5-1.2%, surfactant 1-2%, preservative 0.8-1.2% and water as the balance.

3. The antibacterial, antipruritic and mosquito repellent essence according to claim 1, characterized in that: The alcohol solvent is a mixture of propylene glycol and ethanol, and the mass ratio of the two is 1:1-3.

4. The antibacterial, antipruritic and mosquito repellent essence according to claim 1, characterized in that: The mass ratio of the geranium oil, the peony extract and the wormwood extract is 1-3:1:1-2.

5. The antibacterial, antipruritic and mosquito repellent essence according to claim 4, characterized in that: The mass ratio of the geranium oil, the peony extract and the wormwood extract is 3:1:

2.

6. The antibacterial, antipruritic and mosquito repellent essence according to claim 1, characterized in that: The mass ratio of the PEG-40 hydrogenated castor oil to the polyoxyethylene alkylphenol ether is 3-5:

1.

7. The antibacterial, antipruritic and mosquito repellent essence according to claim 1, characterized in that: The mass ratio of the surfactant, ethyl butyl acetylaminopropionate and the plant extract is 1-2:1.5-2.5:0.5-1.

2.

8. The antibacterial, antipruritic and mosquito repellent essence according to claim 7, characterized in that: The mass ratio of the surfactant, ethyl butyl acetylaminopropionate and the plant extract is 1.5:2:

1.

9. The antibacterial, antipruritic and mosquito repellent essence according to claim 1, characterized in that: The preservative is a composite preservative of ethylhexylglycerin, caprylhydroxamic acid, 1,3-propylene glycol and 1,2-hexanediol.

10. The method for preparing the antibacterial, antipruritic and mosquito repellent essence according to any one of claims 1 to 9, characterized in that: The steps include: (1) After heating water to 85° C., add allantoin and propylene glycol and stir until uniform to obtain a mixture A, which is set aside; (2) mixing borneol, menthol, ethyl butyl acetylaminopropionate and ethanol, stirring until uniform, then adding to mixture A, and continuing to stir until uniform while keeping warm, to obtain mixture B; (3) mixing menthyl glycol, plant extract and surfactant evenly and adding the mixture to mixture B, cooling to 65° C., maintaining the temperature and stirring evenly to obtain mixture C; (4) Add the preservative to the mixture C and stir evenly, then cool to room temperature to obtain the antibacterial, antipruritic and mosquito repellent essence.

Images