Traditional Chinese medicine composition with effects of strengthening spleen and stomach and clearing heat and dispersing blood stasis as well as preparation method and application of traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition with double effects of strengthening spleen and stomach and clearing heat and dispersing blood stasis as well as a preparation method and application of the traditional Chinese medicine composition. The composition is prepared from radix codonopsis, rhizoma atractylodis macrocephalae, poria cocos, liquorice, radix scutellariae, radix salviae miltiorrhizae, radix paeoniae rubra, pericarpium citri reticulatae, fructus crataegi and semen coicis according to a specific proportion through compatibility, and the dual effects of strengthening the spleen and stomach and clearing away heat and dispersing blood stasis are achieved through the synergistic effect. The preparation method comprises the steps of raw material cleaning, soaking, decocting, filtering, concentrating and preparation forming (such as pills, capsules, granules or oral liquid). The process is simple and suitable for large-scale production. The composition is suitable for symptoms such as weakness of the spleen and the stomach, dyspepsia, in-vivo stagnant heat, blood stasis and dysmenorrhea, and clinical experiments show that the composition can significantly improve the symptoms of more than 90% of patients with weakness of the spleen and the stomach and more than 85% of patients with stagnant heat. The traditional Chinese medicine composition solves the problem of single efficacy of the existing traditional Chinese medicine, has the advantages of synergistic interaction, various dosage forms, wide application and the like, and has a good market prospect.

Description

[0001] The present invention relates to the technical field of traditional Chinese medicine, and in particular to a traditional Chinese medicine composition having the effects of strengthening the spleen and stomach, clearing away heat and removing blood stasis, and a preparation method and application thereof. The composition can effectively improve symptoms such as spleen and stomach weakness, indigestion, and blood stasis in the body through scientific compatibility, and has broad application prospects. Background Art

[0002] In modern life, due to factors such as irregular diet, high stress, and environmental pollution, spleen and stomach dysfunction and internal heat problems are becoming increasingly common. The spleen and stomach are the foundation of acquired constitution and the source of qi and blood biochemical transformation. Weak spleen and stomach can lead to symptoms such as indigestion, loss of appetite, and fatigue; while internal heat may cause inflammation, pain, blood stasis and other problems. Although existing Chinese medicines have the effects of strengthening the spleen and stomach or clearing away heat and removing blood stasis, they often have a single effect and it is difficult to take both into account at the same time. Therefore, it is of great significance to develop a Chinese medicine composition that can both strengthen the spleen and stomach and clear away heat and remove blood stasis. Summary of the invention

[0003] The invention aims to provide a Chinese medicine composition with the dual effects of strengthening spleen and stomach, clearing away heat and removing blood stasis, and discloses its preparation method and application. The composition can synergize and enhance the effect through scientific compatibility, and is suitable for symptoms such as spleen and stomach weakness, indigestion, and blood stasis in the body. Technical Solution

[0004] 1. Composition of Chinese medicine composition The Chinese medicine composition of the present invention is composed of the following raw materials in parts by weight: Codonopsis: 10-20g Efficacy: Nourish the middle and replenish qi, strengthen the spleen and benefit the lungs.

[0005] Atractylodes macrocephala: 10-15 g Efficacy: Strengthens the spleen and replenishes Qi, dries dampness and promotes diuresis.

[0006] Poria: 10-15 g Efficacy: Diuretic and dampness-eliminating, spleen-strengthening and mind-calming.

[0007] Licorice: 5-10 grams Efficacy: Nourishes the spleen and replenishes Qi, clears away heat and detoxifies, and harmonizes various medicines.

[0008] Scutellaria baicalensis: 10-15 g Efficacy: Clears away heat and dampness, purges fire and detoxifies.

[0009] Salvia miltiorrhiza: 10-15 grams Efficacy: Promote blood circulation, remove blood stasis, clear the heart and relieve restlessness.

[0010] Red peony root: 10-15g Efficacy: Clears heat and cools blood, disperses blood stasis and relieves pain.

[0011] Tangerine peel: 5-10 g Efficacy: Regulates Qi and strengthens the spleen, dries dampness and resolves phlegm.

[0012] Hawthorn: 10-15 grams Efficacy: Helps digestion, eliminates stagnation, promotes qi and relieves blood stasis.

[0013] Job's tears: 10-15g Efficacy: Strengthen the spleen and eliminate dampness, clear away heat and discharge pus.

[0014] 2. Preparation method The Chinese medicine composition of the present invention can be prepared by the following steps: Step 1: Prepare the ingredients Weigh each medicinal material according to the above ratio to ensure that the quality of the medicinal materials meets the standards of the "Chinese Pharmacopoeia".

[0015] Step 2: Cleaning Rinse the herbs with clean water to remove sand and impurities.

[0016] Step 3: Soak Put the cleaned medicinal materials into a container, add clean water 5-10 times the total weight of the medicinal materials, and soak for 30-60 minutes to allow the medicinal materials to fully absorb water.

[0017] Step 4: Cooking Heat the soaked herbs until boiling, then simmer over low heat for 30-40 minutes. Stir appropriately during the decocting process to ensure that the active ingredients are fully dissolved.

[0018] Step 5: Filter After decoction is completed, filter the medicine liquid with gauze or filter to remove the residue.

[0019] Step 6: Concentrate Continue to heat and concentrate the filtered medicinal solution until the volume of the medicinal solution is reduced to 1 / 3-1 / 2 of the original volume.

[0020] Step 7: Preparation According to actual needs, the concentrate is made into the following dosage forms: Pills: Add appropriate amount of honey or starch to make pills.

[0021] Capsules: The concentrate is dried to make powder and filled into capsules.

[0022] Granules: Add appropriate amount of dextrin or sucrose to make granules.

[0023] Oral solution: Directly package the concentrate into oral solution.

[0024] 3. Application The Chinese medicine composition of the present invention has the following applications: Strengthen the spleen and stomach: suitable for symptoms such as weak spleen and stomach, indigestion, loss of appetite, abdominal distension and loose stools.

[0025] Clearing away heat and removing blood stasis: Suitable for symptoms such as internal heat, blood stasis, dysmenorrhea, inflammation, skin sores, etc.

[0026] Comprehensive conditioning: It is suitable for patients with weak spleen and stomach and internal heat stasis, and has a comprehensive conditioning effect. DETAILED DESCRIPTION

[0027] Example 1: Preparation of pills Weigh 15 grams of Codonopsis pilosula, 12 grams of Atractylodes macrocephala, 12 grams of Poria cocos, 8 grams of Licorice, 12 grams of Scutellaria baicalensis, 12 grams of Salvia miltiorrhiza, 12 grams of Red Peony Root, 8 grams of Tangerine Peel, 12 grams of Hawthorn, and 12 grams of Coix Seed according to the proportion.

[0028] After washing the herbs, add 800 ml of water and soak for 40 minutes.

[0029] Decoction for 30 minutes and filter the liquid.

[0030] Concentrate the medicinal liquid to 200 ml, add appropriate amount of honey and make it into pills.

[0031] Example 2: Preparation of capsules Weigh 20 grams of Codonopsis pilosula, 15 grams of Atractylodes macrocephala, 15 grams of Poria cocos, 10 grams of Licorice, 15 grams of Scutellaria baicalensis, 15 grams of Salvia miltiorrhiza, 15 grams of Red Peony Root, 10 grams of Tangerine Peel, 15 grams of Hawthorn, and 15 grams of Coix Seed according to the proportion.

[0032] After washing the herbs, add 1000 ml of water and soak for 60 minutes.

[0033] Decoction for 40 minutes and filter the liquid.

[0034] The liquid medicine is concentrated to 300 ml, dried and made into powder, and filled into capsules.

[0035] Example 3: Preparation of oral solution Weigh 10 grams of Codonopsis pilosula, 10 grams of Atractylodes macrocephala, 10 grams of Poria cocos, 5 grams of Licorice, 10 grams of Scutellaria baicalensis, 10 grams of Salvia miltiorrhiza, 10 grams of Red Peony Root, 5 grams of Tangerine Peel, 10 grams of Hawthorn, and 10 grams of Coix Seed according to the proportion.

[0036] After washing the herbs, add 500 ml of water and soak for 30 minutes.

[0037] Decoction for 30 minutes and filter the liquid.

[0038] Concentrate the liquid medicine to 150 ml and package it into oral solution.

[0039] advantage Dual effects: It has the effects of strengthening the spleen and stomach, clearing away heat and removing blood stasis, and has a wide range of applications.

[0040] Synergistic effect: The medicinal materials are scientifically matched and work together to enhance the efficacy.

[0041] Easy preparation: The preparation method is simple and easy to scale up.

[0042] Various dosage forms: It can be made into pills, capsules, granules or oral liquids as needed, which is convenient for patients to use.

[0043] Experimental data To verify the efficacy of the present invention, the following experiments were performed: Spleen-strengthening and stomach-regulating experiment: 100 patients with spleen and stomach deficiency were selected. After taking the composition of the present invention for 4 weeks, the symptoms of more than 90% of the patients were significantly improved.

[0044] Heat-clearing and blood-stasis-removing experiment: 80 patients with heat stasis in the body were selected. After taking the composition of the present invention for 4 weeks, the symptoms of more than 85% of the patients were significantly relieved.

[0045] in conclusion The Chinese medicine composition provided by the present invention, as well as its preparation method and application, has significant effects of strengthening the spleen and stomach, clearing away heat and removing blood stasis, is applicable to a variety of related symptoms, and has good market prospects and application value.

Claims

1. A Chinese medicine composition having the effects of strengthening the spleen and stomach, clearing away heat and removing blood stasis, characterized in that: It is composed of the following raw materials in parts by weight: Codonopsis pilosula 10-20 grams, Atractylodes macrocephala 10-15g, Poria 10-15g, 5-10 grams of licorice, 10-15g of Scutellaria baicalensis, 10-15g of Salvia miltiorrhiza, 10-15g red peony root, 5-10 grams of dried tangerine peel, Hawthorn 10-15 grams, 10-15 grams of coix seed.

2. The Chinese medicine composition according to claim 1, characterized in that: The preferred weight portions of each raw material are: Codonopsis pilosula 15g, Atractylodes macrocephala 12g, Poria 12g, 8 grams of licorice, Scutellaria baicalensis 12g, Salvia miltiorrhiza 12g, 12g red peony root, 8 grams of dried tangerine peel, Hawthorn 12g, 12 grams of coix seed.

3. The Chinese medicine composition according to claim 1 or 2, characterized in that: The dosage form of the composition is pills, capsules, granules or oral liquid.

4. A method for preparing the Chinese medicine composition according to any one of claims 1 to 3, characterized in that: The following steps are involved: a. Raw material preparation: weigh each medicinal material according to the proportion; b. Cleaning: Rinse the herbs with clean water to remove impurities; c. Soaking: Soak the herbs in 5-10 times their weight of water for 30-60 minutes; d. Decoction: Heat to boiling and simmer for 30-40 minutes; e. Filtration: remove the drug residue and collect the filtrate; f. Concentration: Concentrate the filtrate to 1 / 3-1 / 2 of the original volume; g. Preparation molding: Make the concentrated liquid into pills, capsules, granules or oral liquid.

5. The preparation method according to claim 4, characterized in that: The specific method of forming the preparation is: Pills: Add honey or starch to make pills; Capsules: The concentrate is dried into powder and then filled into capsules; Granules: Add dextrin or sucrose to make granules; Oral solution: Directly dispense the concentrate.

6. Use of the Chinese medicine composition according to any one of claims 1 to 3 in the preparation of medicines for treating the following diseases: Weak spleen and stomach, indigestion, loss of appetite, abdominal distension and loose stools; Heat in the body, blood stasis, dysmenorrhea, inflammation or skin sores.

7. The use according to claim 6, characterized in that: The medicine is used for comprehensive conditioning to simultaneously improve spleen and stomach dysfunction and symptoms of stasis and heat in the body.