Giant salamander polypeptide powder composition formula for tumor rehabilitation

Abstract

The invention belongs to the field of biological pharmacy, and particularly relates to a giant salamander polypeptide powder composition formula for tumor rehabilitation, which is prepared from the following components in parts by weight: giant salamander polypeptide, sea cucumber polypeptide, soybean polypeptide, whey protein powder, L-arginine, L-glutamine, rhizoma polygonati powder, Chinese yam powder, poria cocos powder, Chinese wolfberry fruit powder, yeast-beta-glucan and medium-chain grease. According to the andrias davidianus polypeptide composition, the andrias davidianus polypeptide and various high-quality proteins are used for assisting tissue repair, and the andrias davidianus polypeptide and the like are used for assisting tissue repair. L-arginine and the like are used for enhancing immunoregulation. Rhizoma polygonati powder and the like are combined to regulate spleen and stomach and promote digestion and absorption. Chinese wolfberry powder and the like play multiple effects, and a good rehabilitation internal environment is created. And stevioside as a natural sweetening agent has no extra burden. The raw materials are natural and safe and are scientifically proportioned, so that a product which is rich in nutrition, safe, reliable and remarkable in effect is provided for tumor rehabilitation people, and comprehensive rehabilitation is assisted.

Description

Technical Field

[0001] The invention belongs to the field of biopharmaceuticals, and specifically is a formula of a giant salamander polypeptide powder composition for tumor rehabilitation. Background Art

[0002] Tumors are major diseases that seriously threaten human health, and their pathogenesis is complex. When the body is under the continuous action of various tumorigenic factors, local tissue cells will proliferate abnormally and then form new organisms. Tumor tissues differ from the normal tissues from which they originate in terms of cell morphology and tissue structure to varying degrees. This difference is called atypia. It is an intuitive presentation of abnormal differentiation of tumors in morphology. By judging the size of atypia, it has become a key histological basis for diagnosing tumors and determining whether they are benign or malignant. Specifically, the atypia of benign tumor cells is usually not significant, and they are generally similar to the source tissues in morphology and structure; while malignant tumors often have obvious atypia, and the cell morphology and tissue structure are very different from normal tissues.

[0003] Once people are unfortunately diagnosed with a malignant tumor, surgery is usually the first treatment. However, surgery is only the first step in treatment, and the postoperative recovery process is also crucial. At this stage, patients need to take medication and other methods to assist recovery.

[0004] However, there are many problems that need to be solved in the current tumor rehabilitation methods:

[0005] On the one hand, the existing tumor rehabilitation drugs are poorly absorbed by the human body. This means that even if patients take the drugs on time and in the right amount, the drugs are difficult to fully play their due role and cannot efficiently participate in the body's repair and recovery process, which greatly affects the recovery process.

[0006] On the other hand, surgery causes great trauma to the patient's body, resulting in a sharp decrease in the patient's immunity after surgery. At this time, the patient's body's ability to resist external pathogens is greatly weakened, and the wound is very susceptible to infection. Once the wound is infected, it will not only prolong the recovery period, but may also cause a series of complications, which may even threaten life and health in severe cases, making tumor recovery more difficult.

[0007] To this end, the present invention provides a formula of a giant salamander polypeptide powder composition for tumor rehabilitation. Summary of the invention

[0008] In order to make up for the deficiencies of the prior art, at least one technical problem raised in the background technology is solved.

[0009] The technical solution adopted by the present invention to solve the technical problem is: the formula of the giant salamander polypeptide powder composition for tumor rehabilitation described in the present invention is characterized in that the formula is composed of the following components in parts by weight:

[0010] 3-9 parts of giant salamander polypeptide;

[0011] 10-18 portions of sea cucumber polypeptide, wherein the concentration of the sea cucumber polypeptide is 50%;

[0012] 30-70 parts of soybean peptides;

[0013] 15-45 servings of whey protein powder;

[0014] 5-35 parts of L-arginine;

[0015] 5-35 parts of L-glutamine;

[0016] 15-45 parts of Polygonatum sibiricum powder;

[0017] 15-45 parts of yam powder;

[0018] 15-45 parts of Poria powder;

[0019] 5-35 parts of wolfberry powder, wherein the wolfberry powder contains 40% polysaccharide;

[0020] 0.5-3.5 parts of yeast-β-glucan, wherein the concentration of the yeast-β-glucan is 90%;

[0021] 180-220 parts of medium chain fats;

[0022] Linseed oil 50% microcapsule powder 40-80 parts;

[0023] Sodium caseinate 5-20 parts;

[0024] 1-7 parts of monoglyceride;

[0025] 3-9 parts of oligofructose;

[0026] Stevioside 0.5-3.5 parts.

[0027] A preparation process of a giant salamander polypeptide powder composition formula for tumor rehabilitation, characterized in that it is used to prepare the giant salamander polypeptide powder composition formula for tumor rehabilitation according to claim 1, and the preparation process comprises the following steps:

[0028] S1. Preprocessing:

[0029] Remove mucus: Scrape off the mucus from the stewed giant salamander;

[0030] Bleeding: Cut the neck of the giant salamander with a knife, collect the blood and freeze it for later use;

[0031] Freeze the head, tail and limbs for later use;

[0032] S2, putting the pre-treated giant salamander meat into a universal grinder and crushing it;

[0033] S3, enzymolysis: adding clean water to the crushed giant salamander meat to prepare a feed liquid, wherein the ratio of clean water to giant salamander meat in the feed liquid is 1:4, adding complex enzyme to the feed liquid, wherein the amount of complex enzyme added is 1.2-10‰, the enzymolysis temperature is 45-60°C, and the enzymolysis time is 2-8h to prepare an enzymolysis solution;

[0034] S4, centrifugation: the enzymatic hydrolysate is placed in a centrifuge for centrifugation at a speed of 4000-20000 r / min for 3-10 minutes;

[0035] S5, concentration: the supernatant after centrifugation is concentrated at a temperature of 50-55°C and a pressure of -0.1Mpa, and after concentration, condensation is performed at a temperature of 10-11°C to prepare a giant salamander polypeptide powder material;

[0036] S6, spray drying: putting the giant salamander polypeptide powder material into a spray dryer for spray drying, the amount of the giant salamander polypeptide powder material is 5-20%, the inlet temperature of the spray dryer is 100-170° C., and the outlet temperature of the spray dryer is controlled at 70-95° C. to prepare the giant salamander polypeptide powder;

[0037] S7, mixing: firstly, pre-mix the giant salamander polypeptide, sea cucumber polypeptide, soybean polypeptide, whey protein powder, L-arginine and L-glutamine at room temperature at a stirring speed of 100-200 r / min for 10-15 minutes to form a basic mixed powder; then add polygonatum powder, yam powder, poria powder and wolfberry powder and continue to stir and mix for 15-20 minutes, and increase the stirring speed to 200-300 r / min; then slowly add yeast-β-glucan, sodium caseinate, monoglyceride, oligofructose and stevioside in sequence, while maintaining a stirring speed of 300-400 r / min and mixing for 20-30 minutes; finally, slowly add medium-chain fats and linseed oil 50% microcapsule powder under continuous stirring, stir evenly, and let stand at 30-40°C for 1-2 hours to fully blend the ingredients.

[0038] Preferably, in step S7, after the mixing is completed, granulation is performed so that the particle size distribution of the finished product of the composition is between 100-300 meshes.

[0039] Preferably, the particles are processed and subjected to moisture control treatment to reduce the moisture content of the finished product to less than 5%.

[0040] Preferably, after the moisture control treatment is completed, the finished product is packaged, and the shelf life of the packaged finished product in a room temperature and light-proof environment is not less than 24 months.

[0041] The beneficial effects of the present invention are as follows:

[0042] 1. The giant salamander polypeptide powder composition formula for tumor rehabilitation described in the present invention has an amino acid composition that is highly compatible with the human body and has a very high absorption rate, providing basic and critical nutritional support for tumor rehabilitation patients. Combined with sea cucumber polypeptides, soybean polypeptides and whey protein powder, a variety of high-quality proteins work synergistically to fully meet the body's high demand for protein during the rehabilitation stage, help the rapid repair and regeneration of damaged tissues, and enhance the body's resistance. For example, in the case of postoperative physical weakness and massive protein loss, these polypeptides and protein powders can quickly replenish nitrogen sources, promote muscle synthesis, and improve the patient's physical condition. .

[0043] 2. The formula of a giant salamander polypeptide powder composition for tumor rehabilitation described in the present invention, the L-arginine, L-glutamine and yeast-β-glucan in the formula play an important role in immunoregulation. L-arginine can stimulate the proliferation and activity of key cells of the immune system, such as lymphocytes, effectively enhance the body's immune response ability, and reduce the risk of postoperative infection. L-glutamine provides energy for immune cells, maintains the integrity of the intestinal mucosal barrier, prevents the invasion of bacteria and viruses, and enhances overall immunity from the level of the intestinal immune defense line. Yeast-β-glucan can activate immune cells such as macrophages and natural killer cells, enhance their ability to recognize and kill pathogens, and build a solid immune defense line for tumor rehabilitation patients.

[0044] 3. The giant salamander polypeptide powder composition formula for tumor rehabilitation described in the present invention, the combination of polygonatum powder, yam powder and poria powder, has a good conditioning effect on spleen and stomach function. Polygonatum replenishes qi and nourishes yin, which helps to improve the state of spleen and stomach weakness; yam is rich in amylase and other substances, which can promote the digestion and decomposition of food; poria is diuretic and insulated, which can regulate the water metabolism of the gastrointestinal tract and improve the digestive environment. The synergistic effect of these three can enhance the digestive function of tumor rehabilitation patients, enable patients to better absorb other nutrients, such as polypeptides, vitamins and minerals, etc., improve the utilization rate of nutrients, and provide sufficient energy and material basis for physical rehabilitation.

[0045] 4. The giant salamander polypeptide powder composition formula for tumor rehabilitation described in the present invention, wolfberry powder is rich in polysaccharides, vitamins and minerals, has multiple functions such as anti-oxidation and immune regulation, can reduce the body's oxidative stress response during tumor rehabilitation, protect cells from free radical damage, and further enhance immunity. Medium-chain oils are quickly digested and absorbed, and can quickly provide energy to the body to meet the high energy consumption needs of tumor patients during the rehabilitation stage. Flaxseed oil 50% microcapsule powder is rich in unsaturated fatty acids, which helps regulate blood lipids, improve cardiovascular function, and create a good internal environment for the overall recovery of the body. Sodium caseinate not only increases the nutritional value of the product, but also stabilizes the product system and improves the taste; monoglycerides ensure that the oil is evenly dispersed and improve product stability; oligofructose, as a prebiotic, promotes the growth of beneficial intestinal bacteria, optimizes the intestinal microecology, and indirectly improves the health level of the body.

[0046] 5. The giant salamander polypeptide powder composition formula for tumor rehabilitation described in the present invention uses stevioside as a natural sweetener, which adds a suitable sweetness to the product while generating almost no heat, thus avoiding an additional burden on the body of tumor rehabilitation patients. It is especially suitable for patients who need to control blood sugar and calorie intake. The raw materials selected for the entire formula are all natural and safe substances. Through scientific and reasonable proportions, it provides a nutritious, effective, safe and reliable product for tumor rehabilitation people, which helps to improve the quality of life of patients and promote comprehensive physical recovery. DETAILED DESCRIPTION

[0047] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific implementation methods.

[0048] A formula of a giant salamander polypeptide powder composition for tumor rehabilitation according to an embodiment of the present invention is characterized in that the formula is composed of the following components in parts by weight:

[0049] 3-9 parts of giant salamander polypeptide;

[0050] 10-18 portions of sea cucumber polypeptide, wherein the concentration of the sea cucumber polypeptide is 50%;

[0051] 30-70 parts of soybean peptides;

[0052] 15-45 servings of whey protein powder;

[0053] 5-35 parts of L-arginine;

[0054] 5-35 parts of L-glutamine;

[0055] 15-45 parts of Polygonatum sibiricum powder;

[0056] 15-45 parts of yam powder;

[0057] 15-45 parts of Poria powder;

[0058] 5-35 parts of wolfberry powder, wherein the wolfberry powder contains 40% polysaccharide;

[0059] 0.5-3.5 parts of yeast-β-glucan, wherein the concentration of the yeast-β-glucan is 90%;

[0060] 180-220 parts of medium chain fats;

[0061] Linseed oil 50% microcapsule powder 40-80 parts;

[0062] Sodium caseinate 5-20 parts;

[0063] 1-7 parts of monoglyceride;

[0064] 3-9 parts of oligofructose;

[0065] Stevioside 0.5-3.5 parts.

[0066] A preparation process of a giant salamander polypeptide powder composition formula for tumor rehabilitation, characterized in that it is used to prepare the giant salamander polypeptide powder composition formula for tumor rehabilitation according to claim 1, and the preparation process comprises the following steps:

[0067] S1. Preprocessing:

[0068] Remove mucus: Scrape off the mucus from the stewed giant salamander;

[0069] Bleeding: Cut the neck of the giant salamander with a knife, collect the blood and freeze it for later use;

[0070] Freeze the head, tail and limbs for later use;

[0071] S2, putting the pre-treated giant salamander meat into a universal grinder and crushing it;

[0072] S3, enzymolysis: adding clean water to the crushed giant salamander meat to prepare a feed liquid, wherein the ratio of clean water to giant salamander meat in the feed liquid is 1:4, adding complex enzyme to the feed liquid, wherein the amount of complex enzyme added is 1.2-10‰, the enzymolysis temperature is 45-60°C, and the enzymolysis time is 2-8h to prepare an enzymolysis solution;

[0073] S4, centrifugation: the enzymatic hydrolysate is placed in a centrifuge for centrifugation at a speed of 4000-20000 r / min for 3-10 minutes;

[0074] S5, concentration: the supernatant after centrifugation is concentrated at a temperature of 50-55°C and a pressure of -0.1Mpa, and after concentration, condensation is performed at a temperature of 10-11°C to prepare a giant salamander polypeptide powder material;

[0075] S6, spray drying: putting the giant salamander polypeptide powder material into a spray dryer for spray drying, the amount of the giant salamander polypeptide powder material is 5-20%, the inlet temperature of the spray dryer is 100-170° C., and the outlet temperature of the spray dryer is controlled at 70-95° C. to prepare the giant salamander polypeptide powder;

[0076] S7, mixing: firstly, pre-mix the giant salamander polypeptide, sea cucumber polypeptide, soybean polypeptide, whey protein powder, L-arginine and L-glutamine at room temperature at a stirring speed of 100-200 r / min for 10-15 minutes to form a basic mixed powder; then add polygonatum powder, yam powder, poria powder and wolfberry powder and continue to stir and mix for 15-20 minutes, and increase the stirring speed to 200-300 r / min; then slowly add yeast-β-glucan, sodium caseinate, monoglyceride, oligofructose and stevioside in sequence, while maintaining a stirring speed of 300-400 r / min and mixing for 20-30 minutes; finally, slowly add medium-chain fats and linseed oil 50% microcapsule powder under continuous stirring, stir evenly, and let stand at 30-40°C for 1-2 hours to fully blend the ingredients.

[0077] In step S7, after the mixing is completed, granulation is performed so that the particle size distribution of the finished product of the composition is between 100-300 meshes.

[0078] After pellet processing, moisture control treatment is carried out to reduce the moisture content of the finished product to less than 5%.

[0079] After completing the moisture control treatment, the finished product is packaged. The shelf life of the packaged finished product in a room temperature and light-proof environment is not less than 24 months.

[0080] Embodiment 1

[0081] Composition formula:

[0082] Giant salamander polypeptide: 3 parts. As a precious biological resource, the polypeptide components of giant salamander have unique biological activity. The composition ratio of giant salamander protein and amino acids is basically the same as that of humans, which makes the absorption and utilization rate of giant salamander polypeptide in the human body extremely high.

[0083] Sea cucumber peptide: 10 parts, and its concentration percentage is 50%. Sea cucumber peptide is rich in a variety of biologically active substances, which has a positive effect on improving the body's immunity and promoting cell repair. In the tumor recovery stage, it can assist in the recovery of body functions.

[0084] Soybean peptide: 30 servings. Soybean peptide has a wide range of sources and contains a variety of essential amino acids for the human body. It can provide a stable nitrogen source for tumor recovery patients and help repair and rebuild body tissues.

[0085] Whey protein powder: 15 servings. Whey protein is a high-quality complete protein that contains all the essential amino acids needed by the human body. The ratio is reasonable and close to the human body's demand ratio. It is easily absorbed and utilized by the human body, and it can supplement the necessary protein nutrition for cancer survivors.

[0086] L-arginine: 5 servings. During the tumor recovery process, L-arginine can participate in the body's immune regulation, enhance the patient's immune function, and help reduce the incidence of complications such as postoperative infection.

[0087] L-glutamine: 5 servings. It is the most abundant free amino acid in the human body. After cancer surgery, it can provide energy for intestinal mucosal cells, maintain intestinal barrier function, and promote intestinal absorption of nutrients.

[0088] Polygonatum odoratum powder: 15 parts. Polygonatum odoratum has the effects of replenishing qi and nourishing yin, strengthening the spleen and moistening the lungs. Its rich polysaccharides, steroidal saponins and other ingredients can improve the body's immunity to a certain extent and help cancer rehabilitation patients improve their weak physical condition.

[0089] Yam powder: 15 servings. Yam contains a variety of nutrients, such as amylase, polyphenol oxidase and other substances, which are beneficial to the recovery of spleen and stomach digestion and absorption function, and provide a good digestive foundation for tumor recovery people.

[0090] Poria powder: 15 parts. Poria has the effects of promoting water and removing dampness, strengthening the spleen and calming the mind. In the composition of giant salamander polypeptide powder, it can help regulate the body's water metabolism and improve the patient's possible discomfort symptoms such as edema.

[0091] Lycium barbarum powder: 5 servings, its sugar content is 40% polysaccharide. Lycium barbarum is rich in various vitamins, minerals and biologically active ingredients such as Lycium barbarum polysaccharide, which can enhance the body's immunity and anti-oxidation, and has a positive significance for the physical recovery of tumor survivors.

[0092] Yeast-β-glucan: 0.5 parts, with a concentration of 90%. Yeast-β-glucan can activate immune cells, enhance the body's immune response, and provide strong support for the human immune system during tumor recovery.

[0093] Medium-chain fats: 180 servings. Medium-chain fats have the characteristics of fast digestion and absorption and rapid energy supply. They can quickly replenish energy for cancer recovery patients and meet the body's high demand for energy during the recovery stage.

[0094] Flaxseed oil 50% microencapsulated powder: 40 servings. Flaxseed oil is rich in unsaturated fatty acids, such as α-linolenic acid. After microencapsulation, its stability is enhanced and it can be better absorbed by the human body. It helps regulate blood lipids, fight inflammation, etc. It is beneficial to the cardiovascular health of cancer recovery patients.

[0095] Sodium caseinate: 5 parts. As a high-quality protein, sodium caseinate plays a role in stabilizing the system and increasing the nutritional value of the product.

[0096] Monoglyceride: 1 part. Monoglyceride has good emulsifying properties, which can evenly disperse the oil components in the composition and ensure the stability and taste of the product.

[0097] Oligofructose: 3 servings. As a prebiotic, oligofructose can promote the growth and reproduction of beneficial intestinal bacteria, improve the intestinal microecological environment, and help improve the digestive function and immunity of cancer recovery patients.

[0098] Stevioside: 0.5 parts. Stevioside is a natural sweetener with high sweetness and low calories. It provides the product with appropriate sweetness without causing excessive burden on the body of cancer recovery patients.

[0099] Preparation process of giant salamander polypeptide powder:

[0100] Step 1: Preprocessing

[0101] a. Remove mucus: Carefully place the fresh giant salamander in a suitable container and remove the mucus on its body surface by scraping. This operation requires extreme caution, ensuring that the mucus is completely removed without causing damage to the skin of the giant salamander, as skin damage may affect the quality of the subsequent giant salamander meat.

[0102] b. Bloodletting: Use a sharp and sterilized knife to precisely cut the neck of the giant salamander and let the blood flow out naturally. Collect the blood and quickly put it into a freezer for future use. The blood may contain some components with potential medicinal value.

[0103] c. Freeze the head, tail and limbs for future use: The processed head, tail and limbs of the giant salamander are properly packaged and placed in a freezer. These parts may be used for other research or product development later, and cryopreservation can preserve their biological activity to the greatest extent.

[0104] Step 2: Grinding: Put the pre-treated giant salamander meat into a high-performance universal grinder for grinding. The grinding process requires strict control of the grinding time and speed to ensure that the giant salamander meat is ground to a suitable particle size, providing a good foundation for the subsequent enzymatic hydrolysis step.

[0105] Step 3, enzymolysis: Add an appropriate amount of clean water to the crushed giant salamander meat to make a liquid feed, and the ratio of clean water to giant salamander meat in the liquid feed is precisely controlled to be 1:4. Then, add carefully selected complex enzymes to the liquid feed, and the amount of complex enzymes added is strictly controlled at 7‰. The liquid feed is placed in an environment with a temperature of 50°C for enzymolysis reaction, and the duration is 5 hours. During the enzymolysis process, the liquid feed needs to be constantly stirred to ensure that the enzyme is in full contact with the giant salamander meat, so that the enzymolysis reaction proceeds evenly, thereby producing a high-quality enzymolysis solution.

[0106] Step 4: Centrifugation: Carefully transfer the enzymatic hydrolysate to a centrifuge for centrifugation. The speed of the centrifuge is set to 12000r / min, and the centrifugation time is controlled to 6 minutes. Through the centrifugation operation, the solid residue in the enzymatic hydrolysate is effectively separated from the liquid part, providing a relatively pure supernatant for the subsequent concentration step.

[0107] Step 5, concentration: concentrate the supernatant after centrifugation. Place the supernatant in a specific device, control the concentration temperature to 50°C, and the concentration pressure to -0.1Mpa. During the concentration process, the water gradually evaporates and the solution concentration continues to increase. After the concentration is completed, condensation treatment is performed to quickly reduce the temperature to 10°C to produce giant salamander polypeptide powder material.

[0108] Step 6, spray drying: Place the giant salamander polypeptide powder material into a professional spray dryer for spray drying. The amount of giant salamander polypeptide powder material is controlled at 10%, the inlet temperature of the spray dryer is set to 150°C, and the outlet temperature is precisely controlled at 85°C. During the spray drying process, the material is sprayed into a mist, fully in contact with the hot air, and the water evaporates rapidly, and finally a dry giant salamander polypeptide powder is produced.

[0109] Embodiment 2

[0110] Composition formula:

[0111] A giant salamander polypeptide powder composition for tumor rehabilitation, the weight proportions of each component are as follows:

[0112] Giant salamander polypeptide: 6 parts. In this ratio, the content of giant salamander polypeptide increases, which can further enhance the role of human nutrient absorption and function regulation.

[0113] Sea cucumber peptides: 14 parts, the concentration remains at 50%. More sea cucumber peptides can provide the body with richer bioactive substances, helping to accelerate the body's recovery process.

[0114] Soybean peptide: 50 servings. A relatively large amount of soybean peptide can provide more sufficient nitrogen sources for tumor recovery patients and meet the body's large demand for protein during the repair process.

[0115] Whey protein powder: 30 servings. Adequate whey protein powder can provide patients with high-quality protein, helping to quickly repair body tissues and strengthen the immune system.

[0116] L-arginine: 20 parts. A higher content of L-arginine can significantly enhance the patient's immune function and effectively reduce the risk of postoperative infection.

[0117] L-Glutamine: 20 servings. It helps maintain the integrity of the intestinal mucosa, promotes efficient absorption of various nutrients by the intestine, and provides a solid guarantee for physical recovery.

[0118] Polygonatum sibiricum powder: 30 parts. The increase in the content of Polygonatum sibiricum powder can better play its role in replenishing qi and nourishing yin, strengthening the spleen and moistening the lungs, and improving the patient's weak physical condition.

[0119] Yam powder: 30 servings. Further promote the recovery of the spleen and stomach digestion and absorption function, and create good conditions for the body to absorb and utilize other nutrients.

[0120] Poria powder: 30 parts. It can more effectively regulate the body's water metabolism and relieve the patient's possible edema and other discomfort symptoms.

[0121] Wolfberry powder: 20 servings. Rich wolfberry powder can provide the body with more antioxidants and nutrients, enhance immunity and promote body recovery.

[0122] Yeast-β-glucan: 2 portions. Yeast-β-glucan with a concentration of 90% can more effectively activate immune cells and enhance the body's immune response level.

[0123] Medium chain lipids: 201 parts. Provide patients with continuous and efficient energy supply to meet the body's high energy demand during the recovery stage.

[0124] Flaxseed oil 50% microcapsule powder: 60 servings. Helps maintain cardiovascular health, regulate blood lipids, and provide a good internal environment for overall recovery of the body.

[0125] Sodium caseinate: 12 parts. It plays multiple roles in stabilizing the product system, increasing the nutritional value of the product and improving the taste.

[0126] Monoglyceride: 4 parts. Ensure that the oil components are evenly dispersed in the composition and improve product stability.

[0127] Oligofructose: 6 servings. It can better promote the growth of beneficial intestinal bacteria, optimize the intestinal microecological environment, and enhance digestive function and immunity.

[0128] Stevioside: 1.4 parts. Provides the product with appropriate natural sweetness without adding too much calorie burden.

[0129] Preparation process description:

[0130] The preparation process of the giant salamander polypeptide powder in this embodiment is basically the same as that in Example 1, and the steps of pre-treatment of mucus removal, bleeding, freezing for standby use, crushing, enzymatic hydrolysis, centrifugation, concentration and spray drying strictly follow the operating specifications and parameter settings of Example 1. However, in the actual production process, the specific operation of each step needs to be fine-tuned according to the characteristics of different batches of giant salamander meat and the operating status of the equipment to ensure the stability and consistency of product quality.

[0131] Embodiment 3

[0132] Composition formula:

[0133] A giant salamander polypeptide powder composition for tumor rehabilitation comprises the following components in parts by weight:

[0134] Giant salamander polypeptide: 9 portions. In this formula, the content of giant salamander polypeptide reaches a relatively high level, and its nutritional supplement and physiological regulation effects on the human body are more prominent.

[0135] Sea cucumber peptides: 18 portions, 50% concentration ensures the effectiveness of its bioactive ingredients. It can provide a rich variety of bioactive substances for tumor recovery patients and help the body recover comprehensively.

[0136] Soybean peptides: 70 servings. A large amount of soybean peptides provides patients with sufficient nitrogen sources, meeting the body's large demand for protein during the recovery stage and promoting tissue repair and regeneration.

[0137] Whey protein powder: 45 servings. Rich whey protein powder provides the body with high-quality protein, which helps to enhance immunity and speed up the body's recovery.

[0138] L-arginine: 35 parts. It significantly enhances the patient's immune function and plays an important role in preventing postoperative infection.

[0139] L-glutamine: 35 servings. It has a more significant effect on the maintenance of intestinal mucosa and the promotion of nutrient absorption, providing a solid nutritional foundation for physical recovery.

[0140] Polygonatum odoratum powder: 45 parts. Give full play to its effects of replenishing qi and nourishing yin, strengthening the spleen and moistening the lungs, and effectively improve the weak condition of the patient's body.

[0141] Yam powder: 45 servings. Greatly promotes the recovery of the spleen and stomach digestion and absorption function, ensuring that the body can fully absorb other nutrients.

[0142] Poria powder: 45 parts. More effectively regulate the body's water metabolism and relieve the patient's possible edema and other discomfort symptoms.

[0143] Wolfberry powder: 35 servings. Provides the body with rich antioxidants and nutrients, further enhancing immunity and promoting the body's recovery process.

[0144] Yeast-β-glucan: 3.5 parts, the high concentration of 90% makes it more capable of activating immune cells and enhancing the body's immune response.

[0145] Medium chain lipids: 220 parts. Provides patients with strong and sustained energy support to meet the body's high energy consumption needs during the recovery phase.

[0146] Flaxseed oil 50% microcapsule powder: 80 parts. It plays an important role in maintaining cardiovascular health, regulating blood lipids, and creating a good internal environment for physical recovery.

[0147] Sodium caseinate: 20 parts. It plays a key role in stabilizing the product system, increasing the nutritional value of the product and optimizing the taste.

[0148] Monoglyceride: 7 parts. Ensure that the oil components are evenly and stably dispersed in the composition, improving the overall quality of the product.

[0149] Oligofructose: 9 servings. Greatly promotes the growth of beneficial intestinal bacteria, comprehensively optimizes the intestinal microecological environment, and enhances digestive function and immunity.

[0150] Stevioside: 3.5 parts. It gives the product a suitable natural sweetness without bringing too much calorie burden to the patient's body.

[0151] Preparation process points:

[0152] The preparation process of the giant salamander polypeptide powder of the present embodiment is strictly controlled for each step on the basis of following the basic process of Example 1. For example, in the enzymolysis step, the activity and stability of the complex enzyme are more deeply detected and screened to ensure the efficiency and consistency of the enzymolysis reaction. During the centrifugation process, the operating state of the centrifuge is monitored in real time to ensure the stability of the centrifugal effect. In the concentration and spray drying steps, parameters such as temperature and pressure are more accurately regulated to ensure that the quality and performance of the giant salamander polypeptide powder reach the best state. At the same time, throughout the preparation process, the hygiene standards and quality control system are strictly followed to ensure the safety and reliability of the product.

[0153] In summary, through the formulas and preparation processes of different embodiments, the giant salamander polypeptide powder composition for tumor rehabilitation fully exerts the synergistic effect of each component, utilizes a variety of high-quality raw materials such as giant salamander polypeptides and sea cucumber polypeptides, and combines scientific preparation processes to provide comprehensive and efficient nutritional supplements for people after tumor surgery, which helps to enhance immune function and promote rapid physical recovery.

[0154] The above shows and describes the basic principles, main features and advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A formula of a giant salamander polypeptide powder composition for tumor rehabilitation, characterized in that: The formula consists of the following ingredients in parts by weight: 3-9 parts of giant salamander polypeptide; 10-18 portions of sea cucumber polypeptide, wherein the concentration of the sea cucumber polypeptide is 50%; 30-70 parts of soybean peptides; 15-45 servings of whey protein powder; 5-35 parts of L-arginine; 5-35 parts of L-glutamine; 15-45 parts of Polygonatum sibiricum powder; 15-45 parts of yam powder; 15-45 parts of Poria powder; 5-35 parts of wolfberry powder, wherein the wolfberry powder contains 40% polysaccharide; 0.5-3.5 parts of yeast-β-glucan, wherein the concentration of the yeast-β-glucan is 90%; 180-220 parts of medium chain fats; Linseed oil 50% microcapsule powder 40-80 parts; Sodium caseinate 5-20 parts; 1-7 parts of monoglyceride; 3-9 parts of oligofructose; Stevioside 0.5-3.5 parts.

2. A preparation process of a composition of giant salamander polypeptide powder for tumor rehabilitation, characterized in that: It is used to prepare the giant salamander polypeptide powder composition formula for tumor rehabilitation as described in claim 1, and the preparation process comprises the following steps: S1. Preprocessing: Remove mucus: Scrape off the mucus from the stewed giant salamander; Bleeding: Cut the neck of the giant salamander with a knife, collect the blood and freeze it for later use; Freeze the head, tail and limbs for later use; S2, putting the pre-treated giant salamander meat into a universal grinder and crushing it; S3, enzymolysis: adding clean water to the crushed giant salamander meat to prepare a feed liquid, wherein the ratio of clean water to giant salamander meat in the feed liquid is 1:4, adding complex enzyme to the feed liquid, wherein the amount of complex enzyme added is 1.2-10‰, the enzymolysis temperature is 45-60°C, and the enzymolysis time is 2-8h to prepare an enzymolysis solution; S4, centrifugation: the enzymatic hydrolysate is placed in a centrifuge for centrifugation at a speed of 4000-20000 r / min for 3-10 minutes; S5, concentration: the supernatant after centrifugation is concentrated at a temperature of 50-55°C and a pressure of -0.1Mpa, and after concentration, condensation is performed at a temperature of 10-11°C to prepare a giant salamander polypeptide powder material; S6, spray drying: putting the giant salamander polypeptide powder material into a spray dryer for spray drying, the amount of the giant salamander polypeptide powder material is 5-20%, the inlet temperature of the spray dryer is 100-170° C., and the outlet temperature of the spray dryer is controlled at 70-95° C. to prepare the giant salamander polypeptide powder; S7, mixing: firstly, pre-mix the giant salamander polypeptide, sea cucumber polypeptide, soybean polypeptide, whey protein powder, L-arginine and L-glutamine at room temperature at a stirring speed of 100-200 r / min for 10-15 minutes to form a basic mixed powder; then add polygonatum powder, yam powder, poria powder and wolfberry powder and continue to stir and mix for 15-20 minutes, and increase the stirring speed to 200-300 r / min; then slowly add yeast-β-glucan, sodium caseinate, monoglyceride, oligofructose and stevioside in sequence, while maintaining a stirring speed of 300-400 r / min and mixing for 20-30 minutes; finally, slowly add medium-chain fats and linseed oil 50% microcapsule powder under continuous stirring, stir evenly, and let stand at 30-40°C for 1-2 hours to fully blend the ingredients.

3. The preparation process of a composition formula of giant salamander polypeptide powder for tumor rehabilitation according to claim 2, characterized in that: In step S7, after the mixing is completed, granulation is performed so that the particle size distribution of the finished product of the composition is between 100-300 meshes.

4. The preparation process of a composition formula of giant salamander polypeptide powder for tumor rehabilitation according to claim 3, characterized in that: After pellet processing, moisture control treatment is carried out to reduce the moisture content of the finished product to less than 5%.

5. The preparation process of the composition formula of giant salamander polypeptide powder for tumor rehabilitation according to claim 4, characterized in that: After completing the moisture control treatment, the finished product is packaged. The shelf life of the packaged finished product in a room temperature and light-proof environment is not less than 24 months.