conduit

Abstract

The application discloses a catheter, which comprises a pipe body, a blocking piece and an adjusting piece, the side wall of the pipe body is provided with a spray hole, the blocking piece is connected with the adjusting piece, the adjusting piece is arranged in the pipe body, and the adjusting piece is used for driving the blocking piece to move in the pipe body. The adjusting piece is used for driving the blocking piece to slide in the pipe body, the position of the blocking piece in the pipe body can be controlled by the adjusting piece, the effective liquid spraying length of the catheter can be controlled, and the blood vessel damage caused by spraying the liquid medicine on the non-disease part due to the too long effective liquid spraying length can be avoided.

Description

Technical Field

[0001] This application relates to the field of interventional medical device technology, specifically to a catheter. Background Technology

[0002] This section provides only background information relevant to this disclosure and is not necessarily prior art.

[0003] Deep vein thrombosis (DVT) of the lower extremities is a common and frequently occurring clinical condition. DVT can cause swelling and functional impairment in the affected limb, and in some cases, it can lead to serious complications such as pulmonary embolism, which has a high mortality rate. Currently, the main treatment for DVT is to administer thrombolytic drugs such as urokinase via a catheter. However, existing thrombolytic catheters have distal openings, which can cause leakage of the thrombolytic solution, affecting the treatment's effectiveness.

[0004] In addition, the lengths of thrombi encountered during local thrombolysis are often not uniform, while the drug spray length of existing thrombolytic catheters is fixed, which makes it impossible to spray drugs specifically on thrombi, resulting in drug waste and drug irritation damage to non-thrombus-affected blood vessels. At the same time, excessive drugs can increase the probability of bleeding complications. Summary of the Invention

[0005] Therefore, it is necessary to provide a conduit, including a tube body, a plugging component, and an adjusting component. The side wall of the tube body is provided with a spray hole. The plugging component is connected to the adjusting component. The adjusting component is inserted into the tube body and is used to drive the plugging component to move within the tube body.

[0006] Optionally, the sealing element includes an elastomer, the sidewall of which is at least partially in contact with the inner wall of the tube, and the elastomer is connected to an adjusting element.

[0007] Optionally, the elastomer has a semi-closed structure with an opening at its proximal end that communicates with the lumen of the tube. The elastomer is adapted to expand radially outward under pressure. Optionally, the elastomer includes a first state and a second state. When the elastomer is in the first state, at least a portion of the circumferential sidewall at the point of maximum diameter of the elastomer is spaced apart from the inner wall of the tube. When the elastomer is in the second state, at least a portion of the sidewall of the elastomer abuts against the inner wall of the tube in the circumferential direction to achieve sealing.

[0008] Optionally, the elastomer includes a skeleton and a flow-blocking membrane, the skeleton being connected to an adjustment element, the flow-blocking membrane covering the sidewalls of the skeleton, and the flow-blocking membrane and / or the skeleton being adapted to expand radially to both sides under pressure.

[0009] Optionally, the skeleton includes a first braided wire and a second braided wire, which intersect to form a mesh structure, and the first braided wire and the second braided wire intersect and are movably connected.

[0010] Optionally, the frame includes multiple rod-shaped members arranged in a circumferential array along the adjusting member, with the rod-shaped members inclined relative to the axis of the adjusting member.

[0011] Optionally, the flow-blocking membrane is located radially outside the skeleton, and the flow-blocking membrane is spaced apart from the skeleton at least when the sealing element is in the second state.

[0012] Optionally, the elastomer includes a conical segment and a straight segment, the distal end of the conical segment is connected to an adjusting member, the other end of the conical segment is connected to the straight segment, and the straight segment is provided with at least one annular protrusion structure.

[0013] Optionally, the elastomer includes a plurality of flow-blocking units arranged around the adjusting member, the flow-blocking units being inclined relative to the axis of the adjusting member, two adjacent flow-blocking units overlapping at least partially in the circumferential direction, and two adjacent flow-blocking units intersecting in the radial direction.

[0014] Compared with the prior art, the beneficial effects of the catheter described in this application are:

[0015] This application uses an adjusting component to drive the sealing component to slide within the tube, allowing the adjusting component to control the position of the sealing component within the tube, thereby controlling the effective spray length of the catheter and preventing excessive spray length from spraying medication onto non-lesion sites and causing vascular damage. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the catheter structure in Embodiment 1 of this application;

[0018] Figure 2 This is a schematic diagram of the nozzle structure in Embodiment 1 of this application;

[0019] Figure 3 This is a schematic diagram of another implementation of the nozzle in Embodiment 1 of this application;

[0020] Figure 4 For the purposes of this application Figure 1 Enlarged schematic diagram of the structure at point A in the diagram;

[0021] Figure 5 This is a schematic diagram of the mating structure of the plugging component and the conduit in Embodiment 1 of this application;

[0022] Figure 6 This is a schematic diagram of the mating structure of the plugging component and the conduit in Embodiment 2 of this application;

[0023] Figure 7 This is a schematic diagram of the connection structure between the sealing component and the adjusting component in Embodiment 2 of this application;

[0024] Figure 8 This is a schematic diagram of the structure in Embodiment 2 of this application, showing the spacing between the sealing element and the pipe body;

[0025] Figure 9 This is a schematic diagram of the structure in Embodiment 2 of this application, showing the sealing element fitting into the pipe body.

[0026] Figure 10 This is a schematic diagram of the connection structure between the skeleton and the membrane in Embodiment 2 of this application;

[0027] Figure 11 This is a schematic diagram of the connection structure between the first braided wire and the second braided wire in Embodiment 2 of this application;

[0028] Figure 12 This is a schematic diagram of another connection structure between the first braided wire and the second braided wire in Embodiment 2 of this application;

[0029] Figure 13 This is a schematic diagram of the skeleton structure in Embodiment 2 of this application;

[0030] Figure 14 This is a schematic diagram of another connection structure between the skeleton and the membrane in Embodiment 2 of this application;

[0031] Figure 15 This is a schematic diagram of the structure after the film has expanded in Embodiment 2 of this application;

[0032] Figure 16 This is a schematic diagram of another connection structure between the skeleton and the membrane in Embodiment 2 of this application;

[0033] Figure 17 This is a schematic diagram of the protruding structure in Embodiment 2 of this application on the sealing component;

[0034] Figure 18 This is a schematic diagram of the sealing component in Embodiment 3 of this application;

[0035] Figure 19 This is a structural schematic diagram of the sealing component in Embodiment 3 of this application from another perspective;

[0036] Figure 20 This is a schematic diagram of the axial cross-sectional structure of the sealing component in Embodiment 3 of this application;

[0037] Figure 21This is a schematic diagram of the radial cross-sectional structure of the sealing component in Embodiment 3 of this application.

[0038] The labels in the attached diagram are as follows:

[0039] 100 / 200 / 300, conduit; 110 / 210 / 310, tube body; 111, nozzle; 112, developing structure; 1121, first developing structure; 1122, second developing structure; 113, closing structure;

[0040] 120, sealing element; 121 / 220 / 320, elastomer; 122, connector; 221, opening; 224, connector; 222, skeleton; 2221, first braided filament; 2222, second braided filament; 2224, rod-shaped element;

[0041] 223. Flow-blocking membrane; 2231. First end; 2232. Second end; 2233. Main body; 2234. Linear structure; 225. Conical section; 226. Straight section; 227. Annular protrusion structure;

[0042] 321, Flow choking unit; 3211, First flow choking unit; 3212, Second flow choking unit;

[0043] 130 / / 230 / 330, Adjustment component; 131, First position; 132, Second position. Detailed Implementation

[0044] To make the above-mentioned objectives, features, and advantages of this application more apparent and understandable, the specific embodiments of this application are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of this application. However, this application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this application. Therefore, this application is not limited to the specific embodiments disclosed below.

[0045] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.

[0046] In the field of interventional medical devices, "distal" is usually defined as the end furthest from the operator during surgery, while "proximal" is defined as the end closest to the operator during surgery.

[0047] Example 1

[0048] This embodiment provides a catheter 100, which is used to intervene in the lumen of the human body to provide a delivery channel for implantable devices or drugs. Figure 1As shown, the catheter 100 includes a tube body 110, which has a lumen structure. The tube body 110 includes a proximal opening located at the axial proximal end and a distal opening located at the axial distal end, and the proximal opening and the distal opening are connected.

[0049] One or more nozzles 111 are provided on the sidewall of the pipe body 110. The nozzles 111 are located at the distal end of the pipe body 110 and are arranged radially outward from the pipe body 110. In one embodiment, such as Figure 2 As shown, the sidewall of the tube 110 has multiple nozzles 111, which are arranged along the axial direction of the tube 110, and all nozzles 111 communicate with the proximal opening of the tube 110. In another embodiment, as... Figure 3 As shown, a nozzle 111 is provided on the side wall of the tube 110. The nozzle 111 is arranged along the axial direction of the tube 110 and can be strip-shaped or elliptical. The proximal end of the tube 110 is used to connect to an injector, which is used to inject a fluid drug into the tube 110. The fluid drug flows from the proximal end to the distal end of the tube 110, passing through the inside of the tube 110 and then flowing out through the nozzle 111. The fluid drug includes any one of urokinase, reteplase (rPA), tenecteplase (TNK-rPA), recombinant streptokinase, batroxobin, etc.

[0050] like Figure 2 , Figure 3 As shown, the tube body 110 includes two spaced-apart developing structures 112, with the nozzle 111 located between the two developing structures 112.

[0051] The imaging structure 112 includes a first imaging structure 1121 and a second imaging structure 1122, which are spaced apart and located at the distal end of the tube body 110. The first imaging structure 1121 is located at one end of the distal end, and the second imaging structure 1122 is located at the other end. An orifice 111 is located between the first imaging structure 1121 and the second imaging structure 1122. The imaging structure 112 is made of a radiopaque material, such as tantalum, platinum, or a combination of iridium. The imaging structure 112 has a ring-shaped structure. The tube body 110 includes an inner membrane and an outer membrane arranged coaxially, with the imaging structure 112 located between them. During the use of the catheter 100, by positioning the orifice 111 between the two imaging structures 112, the physician can identify the location of the orifice 111 through the two imaging structures 112, thus facilitating the positioning of the orifice 111 at the lesion site.

[0052] like Figure 4As shown, the conduit 100 also includes a plugging member 120 and an adjusting member 130. The plugging member 120 is connected to the adjusting member 130. The adjusting member 130 is inserted into the tube body 110. The adjusting member 130 is used to drive the plugging member 120 to move within the tube body 110. The adjusting member 130 is used to drive the elastic body to move within the tube body 110.

[0053] The plugging element 120 is made of an elastic material, such as nickel-titanium alloy or polyurethane. When subjected to external pressure, the plugging element 120 can expand radially outward or contract radially inward. When pressure is applied towards the center of the plugging element 120, it is compressed. When pressure is applied radially outward, it expands radially outward. The plugging element 120 is located inside the pipe body 110. The plugging element 120 adheres to the inner wall of the pipe body 110 and possesses a certain elastic force. This adhesion forms a seal, preventing the fluid within the pipe body 110 from flowing towards the distal opening of the pipe body 110.

[0054] The sealing element 120 is connected to the adjusting element 130, which is inserted into the tube body 110. The adjusting element 130 is axially positioned within the tube body 110, with one axial end extending from the proximal end of the tube body 110. The adjusting element 130 can slide axially within the tube body 110. The adjusting element 130 drives the sealing element 120 to slide within the tube body to adjust its position, thereby controlling the effective length of the tube body 110 for fluid delivery to the outside. Specifically, adjusting the position of the sealing element 120 controls the number of nozzles 111 communicating with the proximal opening of the tube body 110, or the communication area between the nozzles 111 and the proximal opening. It can be understood that the more nozzles 111 communicating axially with the proximal opening of the tube body 110, or the larger the communication area between the nozzles 111 and the proximal opening, the longer the effective fluid delivery length of the tube body 110.

[0055] like Figure 4 As shown, the sealing member 120 includes an elastic body 121 and a connecting body 122. The elastic body 121 is connected to and surrounds the connecting body 122. The sidewall of the elastic body 121 is at least partially attached to the inner wall of the tube 110. The connecting body 122 is connected to the adjusting member 130.

[0056] The elastomer 121 is made of an elastic material, such as rubber, polyurethane (TPU, PCU, etc.), or thermoplastic polyolefin elastomer (TPE). The elastomer 121 is welded, bonded, or threaded to the connector 122. The elastomer 121 surrounds the connector 122, with at least a portion located radially outside the connector 122, and its outer diameter is larger than that of the connector 122. The elastomer 121 fits against the inner wall of the tube 110. The connector 122 is made of a rigid material, such as stainless steel or nickel-titanium alloy. An annular positioning groove is formed on the connector 122, and the elastomer 121 is located within this groove, fitting against the inner wall of the groove to achieve a seal.

[0057] Furthermore, the connector 122 is threaded, welded, or bonded to the adjusting member 130. For example, in one embodiment, the connector 122 has a threaded hole, and the adjusting member 130 has an external thread. The adjusting member 130 is inserted into the threaded hole and threadedly connected to the connector 122. The adjusting member 130 drives the elastic body 121 to move within the tube 110 via the connector 122. Thus, during the bending process of the tube 110, the connection between the elastic body 121 and the connector 122, made of a rigid material, allows the connector 122 to support the elastic body 121, preventing the elastic body from deforming under the bending pressure of the tube 110 and causing the adjusting member 130 to bend. This reduces the difficulty of pushing the elastic body 121 within the tube in a bent state.

[0058] For example, in one implementation, such as Figure 5As shown, the plugging member 120 includes an axial first position 131 and an axial second position 132 within the pipe body 110. Both the axial first position 131 and the axial second position 132 are located between the first imaging structure 1121 and the second imaging structure 1122. The axial first position 131 is located on the distal side of the axial second position 132. The distance between the axial first position 131 and the first imaging structure 1121 is x1, and the distance between the axial second position 132 and the first imaging structure 1121 is x2, where x2 > x1. When the plugging member 120 is located at the axial first position 131, the effective liquid spraying length of the pipe body is x1. At this time, the plugging member 120 plugs the spray holes 111 located on the distal side of the plugging member 120. The spray holes 111 located on the distal side of the plugging member 120 are not connected to the proximal opening, and the spray holes 111 located on the proximal side of the plugging member 120 are connected to the proximal opening. The number of spray holes 111 connected to the proximal opening is smaller (i.e., compared with the number of spray holes 111 connected to the proximal opening when the plugging member 120 is in the second position 132) or the area of the spray holes 111 connected to the proximal opening is smaller (i.e., compared with the area of the spray holes 111 connected to the proximal opening when the plugging member 120 is in the second position 132). When the plugging member 120 is located at the axial second position 132, the effective liquid spraying length of the pipe body 110 is x2, where x2 < x1. At this time, the number of spray holes 111 connected to the proximal opening of the pipe body 110 or the area of the spray holes connected to the proximal opening of the pipe body 110 is smaller than the number or the connected area when the plugging member 120 is in the first position 131.

[0059] In this way, the adjusting member 130 drives the plugging member 120 to slide within the pipe body 110, enabling the adjusting member 130 to control the position of the plugging member 120 within the pipe body 110, thereby controlling the effective liquid spraying length of the catheter 100 and avoiding blood vessel damage caused by excessive effective liquid spraying length when spraying liquid medicine on non-lesion sites.

[0060] As Figure 5 shown, the distal end of the pipe body 110 has a necking structure 113. Specifically, the necking structure 113 means that the distal end of the pipe body 110 has a certain taper, that is, the distal end of the pipe body 110 has a conical structure, and the diameter of the conical structure decreases from the side close to the proximal end to the side close to the distal end. The maximum diameter of the necking structure 113 is smaller than the diameter of the plugging member 120. After the sealing member 120 moves towards the distal end to the necking structure 113, the necking structure 113 forms a stop for the plugging member 120 to prevent the plugging member 120 from passing through the distal end of the pipe body 110.

[0061] Embodiment 2

[0062] The difference between this embodiment and Embodiment 1 is that, as Figure 6 、 Figure 7As shown, in the conduit 200, the elastomer 220 has a cavity structure, and the proximal end of the elastomer 220 has an opening 221 that communicates with the cavity structure. The elastomer 220 is adapted to expand radially outward under the pressure of the fluid.

[0063] The elastomer 220 is sleeved on the adjusting member 230. One end of the elastomer 220 is connected to the adjusting member 230, and the other end of the elastomer 220 is positioned towards the proximal end of the adjusting member 230. The distal end of the elastomer 220 is sealed, and the proximal end of the elastomer 220 has an opening 221, which is positioned towards the proximal end. The sidewall and distal end of the elastomer 220 enclose each other to form a semi-closed structure.

[0064] It should be noted that the semi-closed structure refers to a cavity structure with a single-sided opening 221. The sidewall of the elastic body 220 has a certain elasticity. When the sidewall of the elastic body 220 is subjected to pressure toward the center of the tube 210, the sidewall of the elastic body 220 contracts toward the direction closer to the adjusting member 230. When the sidewall of the elastic body 220 is subjected to pressure toward the radially outer side of the tube 210, the sidewall of the elastic body 220 moves away from the adjusting member 230.

[0065] It is understood that in this embodiment, the elastomer 220 can be directly connected to the adjusting member 230, or it can be connected to the adjusting member 230 through the connector 224. For example, in one embodiment, the connector 224 has a ring-shaped structure, the connector 224 is sleeved on the adjusting member 230 and fixedly connected to the adjusting member 230, and the distal end of the elastomer 220 is connected to the connector 224.

[0066] The elastomer 220 includes a first state and a second state, such as Figure 8 As shown, when the elastic body 220 is in the first state, the circumferential sidewall of the radial section at the point of maximum diameter of the elastic body 220 is at least partially spaced from the inner wall of the tube 210, such as... Figure 9 As shown, when the elastomer 220 is in the second state, the circumferential sidewall of the radial section at the maximum diameter of the elastomer 220 is completely fitted with the inner wall of the tube 210 to achieve fluid blockage. When no liquid is injected into the tube 210, the elastomer 220 is in the first state. After the liquid is injected into the tube 210, the liquid enters the cavity structure of the elastomer 220, and the liquid exerts an expansion force on the sidewall of the elastomer 220, causing the sidewall of the elastomer 220 to expand and fit against the inner wall of the tube 210.

[0067] Before the liquid medicine is injected into the tube 210, the elastic body 220 is in its first state. At this time, the part of the elastic body 220 with the largest diameter is at least partially spaced from the inner wall of the tube 210, and the elastic force between the elastic body 220 and the tube 210 is small, which facilitates the movement of the elastic body 220 within the tube 210 by the adjusting member 230. After the adjusting member 230 moves the elastic body 220 to the target position, the liquid medicine is injected into the tube 210. The liquid medicine enters the cavity structure of the elastic body 220 through the tube 210. Under the pressure of the liquid medicine, the elastic body 220 expands radially to both sides until the sidewall of the elastic body 220 with the largest diameter is completely attached to the sidewall of the tube 210, thereby sealing the liquid medicine with the elastic body 220 and adjusting the effective spray length of the tube 210.

[0068] Thus, by employing a cavity-like structure for the elastomer 220, with its sidewalls made of elastic material, during the injection of the drug solution, fluid accumulates within the cavity, creating radially outward pressure on the sidewalls of the elastomer 220. Under this pressure, the elastomer 220 expands radially outward. On one hand, the elastomer 220 adaptively forms a seal under the fluid pressure of the drug solution; on the other hand, the greater the fluid pressure on the elastomer 220, the stronger the elastic force between the elastomer 220 and the inner wall of the tube 210, thereby increasing the stability of the elastomer 220 on the inner wall of the tube 210. When the tube 210 is not filled with drug solution, there is a certain distance between the maximum diameter of the elastomer 220 and the tube 210, facilitating position adjustment of the tube 210 or the retraction of the elastomer 220.

[0069] like Figure 10 As shown, the elastomer 220 includes a skeleton 222 and a flow-blocking membrane 223. One end of the skeleton 222 is connected to the adjusting member 230, and the other end of the skeleton 222 is disposed towards the proximal end of the tube 210. The circumferential sidewall of the skeleton 222 is inclined relative to the center of the tube 210 (e.g., Figure 9 The proximal diameter of the skeleton 222 is larger than the distal diameter. It is understood that in other embodiments, the diameter of the skeleton 222 increases from the direction near the proximal end towards the direction near the distal end. A flow-blocking membrane 223 covers the sidewall of the skeleton 222, forming a semi-closed structure with the skeleton 222. The flow-blocking membrane 223 forms a seal on the sidewall of the skeleton 222. After the fluid enters the inside of the skeleton 222, it is hindered by the flow-blocking membrane 223 and has difficulty passing through the elastomer 220, thus creating a radially outward expanding force on the skeleton 222 and the flow-blocking membrane 223.

[0070] like Figure 11As shown, the skeleton 222 includes a mesh structure, which can be formed by weaving braided wires or by heat-setting a nickel-titanium metal tube after laser cutting. A flow-blocking membrane 223 covers the sidewalls of the skeleton 222. The mesh structure is made of an elastic material, such as a nickel-titanium alloy, medical-grade stainless steel wire, or other similar material.

[0071] In one implementation, such as Figure 11 As shown, the first braided wire 2221 and the second braided wire 2222 only intersect but are not fixed. The first braided wire 2221 and the second braided wire 2222 are movably connected. The first braided wire 2221 and the second braided wire 2222 can move relative to each other under the action of external force, so that the skeleton 222 can expand radially outward under the action of pressure towards the radially outward. In another embodiment, as... Figure 12 As shown, the mesh structure includes a first braided wire 2221 and a second braided wire 2222. The first braided wire 2221 and the second braided wire 2222 intersect to form a mesh structure, and the intersection point 2223 of the first braided wire 2221 and the second braided wire 2222 is fixedly connected.

[0072] In another implementation, such as Figure 13 As shown, the skeleton 222 includes a frame structure, which includes multiple rod-shaped members 2224. One end of each rod-shaped member 2224 is connected to a connector 224, and the other end of each rod-shaped member 2224 faces the proximal end of the pipe. The connector 224 is connected to an adjusting member 230. The multiple rod-shaped members 2224 are arranged circumferentially along the connector 224, and the rod-shaped members 2224 are inclined relative to the axial direction of the pipe 210. The connector 224 and all the rod-shaped members 2224 together form a conical cylindrical structure. A flow-blocking membrane 223 covers the sidewalls of the rod-shaped members 2224, and the flow-blocking membrane 223, the rod-shaped members 2224, and the connector 224 enclose a semi-closed structure. It is understood that the rod-shaped member 2224 can be hinged to the connector 224, or fixedly connected to the connector 224 and the rod-shaped member 2224 is made of an elastic material, or other connection methods that can enable the rod-shaped member 2224 to expand radially outward under the fluid pressure of the flow-blocking membrane 223.

[0073] In this way, by covering the sidewall of the skeleton 222 with the flow-blocking membrane 223, the flow-blocking membrane 223 can form a blockage on the inside of the tube 210. Then, one end of the skeleton 222 is connected to the adjusting member 230, and the other end of the skeleton 222 faces the proximal end of the tube 210. The sidewall of the skeleton 222 is inclined relative to the axial center of the tube 210, so that the skeleton 222 and the flow-blocking membrane 223 form a semi-closed structure. Thus, after the fluid enters the skeleton 222, the fluid exerts an expansion force on the skeleton 222 and the flow-blocking membrane 223 in a radially outward direction.

[0074] like Figure 14As shown, the flow-blocking membrane 223 is located outside the skeleton 222. The flow-blocking membrane 223 is used to form a blockage on the outside of the skeleton 222. The flow-blocking membrane 223 includes a first end 2231, a second end 2232, and a main body 2233. The first end 2231 is located at the distal end of the main body 2233, and the second end 2232 is located at the proximal end of the main body 2233. The first end 2231 is connected to the distal end of the skeleton 222, and the second end 2232 is connected to the proximal end of the skeleton 222. The main body 2233 is located between the first end 2231 and the second end 2232. There is no constraint between the main body 2233 and the skeleton 222, or the main body 2233 is free from constraint before expanding radially outward to a certain diameter.

[0075] In this embodiment, the main body 2233 is not directly connected to the frame 222. For example, in one implementation, such as Figure 14 As shown, one end of the flow-blocking membrane 223 is sewn to the distal end of the skeleton 222, and the second end 2232 of the flow-blocking membrane 223 is sewn to the proximal end of the skeleton 222. The main body 2233 is not directly connected to the skeleton 222, and there is no adhesive force or constraint between the main body 2233 and the skeleton 222. When the elastomer 220 is in the first state, the main body 2233 is in contact with the skeleton 222. When the elastomer 220 is in the second state, as shown... Figure 15 As shown, the main body 2233 expands radially outward, and is spaced apart from the frame 222. It can be understood that in other embodiments, the first end 2231 and the second end 2232 of the flow-blocking membrane 223 can also be adhered to the frame 222. During actual use of the catheter 200, after the elastomer 220 has adjusted the effective infusion length, medication is injected into the tube body 210. When the medication reaches the elastomer 220, it enters the inner side of the frame 222 and accumulates within the elastomer 220 to generate fluid pressure, causing the flow-blocking membrane 223 to expand and adhere to the sidewall of the tube body 210. When it is necessary to move the position of the elastomer 220 or to remove the elastomer 220, the injection of medication into the tube body 210 is stopped or the liquid in the tube body 210 is withdrawn. At this time, the flow-blocking membrane 223 loses fluid pressure and adheres to the frame 222, thereby facilitating the removal of the elastomer 220.

[0076] In another embodiment, such as Figure 16As shown, the main body 2233 and the skeleton 222 are connected by a thread 2234. The length of the thread 2234 is greater than or equal to the difference between the maximum diameter of the skeleton 222 in the second state and the maximum diameter in the first state. The main body 2233 is located outside the skeleton 222. One end of the thread 2234 is connected to the main body 2233, and the other end is connected to the skeleton 222. The thread 2234 is flexible and made of a polymer material, such as PTFE thread, PET thread, or surgical suture. When the skeleton 222 is in the second state, it is in an expanded state. In this state, the sidewalls of the skeleton 222 are in contact with the inner wall of the tube 210, and the maximum diameter of the skeleton 222 is d1. When the skeleton 222 is in the first state, it is in a contracted state. In this state, the maximum diameter of the skeleton 222 is at least partially spaced from the inner wall of the tube 210, and the maximum diameter of the skeleton 222 is d2. The length L of the linear element 2234 is greater than d1-d2. Thus, the main body 2233 and the skeleton 222 are connected by the linear element 2234. The length of the linear element 2234 is greater than the difference between the maximum diameter of the skeleton 222 in the second state and the maximum diameter in the first state. This allows the linear element 2234 to provide a certain margin for the radially outward movement of the main body 2233. When the main body 2233 is subjected to fluid pressure, it can expand radially outward within the length range of the linear element 2234, thereby achieving the sealing of the pipe 210.

[0077] In this way, the first end 2231 and the second end 2232 of the flow-blocking membrane 223 are connected to the skeleton 222, while the main body 2233 is not connected to the skeleton 222 or is connected by the wire 2234, so that the main body 2233 forms a free section on the skeleton 222, that is, without constraint or without constraint within a certain diameter range, so that the main body 2233 can be freely expanded under the action of fluid pressure, forming a blockage in the tube 210.

[0078] like Figure 17As shown, the elastomer 220 includes a conical section 225 and a straight section 226 connected to each other. One end (specifically the distal end) of the conical section 225 is connected to the adjusting member 230, and the other end of the conical section 225 is connected to the straight section 226. The diameter of the distal end of the conical section 225 is smaller than that of the proximal end, and the diameter of the conical section 225 increases from the proximal end to the distal end, with the largest diameter at the proximal end. The distal end of the conical section 225 is connected to the adjusting member 230, and the proximal end of the conical section 225 is connected to the straight section 226. The sidewall of the conical section 225 is inclined relative to the axis of the tube body 210, and the sidewall of the conical section 225 is inclined radially outward from the tube body 210. The straight section 226 is connected to the proximal end of the conical section 225 and is arranged along the axial direction of the tube body 210. When the elastomer 220 is in the first state, the proximal end of the conical segment 225 and the straight segment 226 are at least partially spaced from the inner wall of the tube 210 in the circumferential direction. When the elastomer 220 is in the second state, the straight segment 226 is at least partially in contact with the inner wall of the tube 210, and the conical segment 225 is at least partially in contact with the inner wall of the tube 210.

[0079] Thus, by including a conical section 225 and a straight section 226 in the elastomer 220, with the proximal end of the conical section 225 connected to the adjusting member 230 and the distal end of the conical section 225 connected to the straight section 226, the straight section 226 extends towards the proximal end of the conical section 225, thereby allowing the skeleton 222 to form a surface contact with the tube body 210 after the elastomer 220 is in the second state, thereby increasing the sealing stability of the elastomer 220.

[0080] like Figure 17 As shown, multiple annular protrusions 227 are provided on the straight section 226, and these annular protrusions 227 are arranged along the axial direction of the straight section 226. The annular protrusions 227 protrude radially outward from the tube body 210, with the convex surface of the annular protrusions 227 facing radially outward from the tube body 210. The annular protrusions 227 can be formed by heat-setting after the skeleton 222 protrudes radially outward, or by stacking the flow-blocking membrane 223 at the protrusion positions. It should be noted that stacking the flow-blocking membrane 223 refers to the flow-blocking membrane 223 being folded into multiple layers and then fixed by stitching or heat-melting bonding. In this way, by providing multiple annular protrusions 227 on the straight section 226, and by arranging the multiple annular protrusions 227 along the axial direction of the straight section 226, the annular protrusions 227 can increase the friction between the elastic body 220 and the inner wall of the tube 210 after the elastic body 220 expands, thereby increasing the positional stability of the elastic body 220 within the tube 210.

[0081] Example 3

[0082] The difference between this embodiment and Embodiment 1 is that, as Figure 18 , Figure 19As shown, in the conduit 300, the elastomer 320 includes a plurality of flow-blocking units 321. One end of the flow-blocking unit 321 is connected to the adjusting member 330. The flow-blocking unit 321 is inclined relative to the axis of the adjusting member 330. The plurality of flow-blocking units 321 are arranged around the adjusting member 330. Two adjacent flow-blocking units 321 overlap at least in the circumferential direction. All flow-blocking units 321 enclose a cavity structure. Two adjacent flow-blocking units 321 are offset in the radial direction.

[0083] The distal end of the flow-restricting unit 321 is connected to the regulating member 330. The proximal end of the flow-restricting unit 321 is a free end and extends towards the proximal end of the pipe body 310. The proximal end of the flow-restricting unit 321 and the regulating member 330 are spaced apart, and the flow-restricting unit 321 is inclined relative to the axis of the regulating member 330. In the axial section of the flow-restricting unit 321, the sidewall of the flow-restricting unit 321 has a straight or arc-shaped structure. When the sidewall of the flow-restricting unit 321 has a straight structure, the proximal and distal ends of the sidewall in the axial section of the flow-restricting unit 321 are located on the same straight line. Figure 20 As shown, when the sidewall of the flow-blocking unit 321 has an arc-shaped structure, the sidewall of the flow-blocking unit 321 protrudes radially outward toward the tube body 310, and the convex surface of the sidewall in the axial section of the flow-blocking unit 321 is arranged radially outward toward the tube body 310. It can be understood that in other embodiments, when the sidewall of the flow-blocking unit 321 has an arc-shaped structure, the sidewall of the flow-blocking unit 321 protrudes toward the center of the tube body 310, and in the axial section of the flow-blocking unit 321, the convex surface of the sidewall of the flow-blocking unit 321 is arranged toward the center of the tube body 310. The flow-blocking unit 321 is made of an elastic material. After being subjected to fluid pressure, the free end of the flow-blocking unit 321 moves radially outward toward the tube body 310 until the free end of the flow-blocking unit 321 is in contact with the sidewall of the tube body 310, and the elastic body 320 is in the second state. When the flow-blocking unit 321 is not subjected to fluid pressure, at least part of the free end of the flow-blocking unit 321 is spaced apart from the free end of the tube body 310. At this time, the elastic body 320 is in the first state.

[0084] Multiple flow-blocking units 321 are arranged around the regulating member 330 in a circumferential array. These units at least partially overlap in the circumferential direction, forming a semi-closed structure, i.e., a cavity structure. An opening is formed at the proximal end of the cavity structure, communicating with it, allowing the cavity structure to contain fluid. Adjacent flow-blocking units 321 are radially offset. This means that, on the radial cross-section of the elastic body 320, the distances between adjacent flow-blocking units 321 and the center of the elastic body 320 are different, allowing them to overlap radially and preventing interference in the circumferential movement of adjacent flow-blocking units 321.

[0085] For example, in one implementation, such as Figure 21 As shown, two adjacent flow-blocking units 321 include a first flow-blocking unit 3211 and a second flow-blocking unit 3212. The first flow-blocking unit 3211 is located radially outside the second flow-blocking unit 3212, and the first flow-blocking unit 3211 and the second flow-blocking unit 3212 overlap at least partially in the circumferential direction. The inner wall of the first flow-blocking unit 3211 is in contact with the outer wall of the second flow-blocking unit 3212. The distance between the inner wall of the first flow-blocking unit 3211 and the center of the elastic body 320 is x1, and the distance between the inner wall of the second flow-blocking unit 3212 and the center of the elastic body 320 is x2. x1 is greater than x2, and the wall thickness of the flow-blocking unit 321 is d = x1 - x2.

[0086] In actual use of the tube body 310, before the liquid medicine is injected into the tube body 310, the elastic body 320 is in the first state. At this time, at least some of the proximal ends of the flow-blocking units 321 are spaced apart from the inner wall of the tube body 310, and the force between the flow-blocking units 321 and the inner wall of the tube body 310 is small, which facilitates the movement of the elastic body 320 within the tube body 310. After the adjusting member 330 moves the elastic body 320 to the target position, the liquid medicine is injected into the tube body 310. The liquid medicine enters the cavity structure formed by multiple flow-blocking units 321 through the tube body 310. Under the pressure of the liquid medicine, the multiple flow-blocking units 321 expand radially to both sides until the proximal ends of the flow-blocking units 321 are in contact with the side walls of the tube body 310, thereby blocking the liquid medicine with the elastic body 320 and realizing the adjustment of the effective spray length of the tube body 310.

[0087] In this way, multiple flow-blocking units 321 are arranged around the circumference of the regulating member 330, and two adjacent flow-blocking units 321 overlap in the circumferential direction, so that all the flow-blocking units 321 enclose a cavity structure. By staggering two adjacent flow-blocking units 321 in the radial direction, the two adjacent flow-blocking units 321 will not interfere with each other during the expansion process, thereby facilitating the flow-blocking units 321 to open under the pressure of the fluid to achieve actual blocking.

[0088] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0089] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.

Claims

1. A catheter, characterized in that, The device includes a tube body, a plugging component, and an adjusting component. The tube body has spray holes on its sidewalls. The plugging component is connected to the adjusting component, which is inserted into the tube body and used to move the plugging component within the tube body. The plugging component includes an elastic body, the sidewall of which is at least partially abutted against the inner wall of the tube body. The elastic body is connected to the adjusting component. The elastic body has a semi-closed structure, with an opening at its proximal end communicating with the lumen of the tube body. The elastic body is adapted to expand radially outward under pressure.

2. The catheter according to claim 1, characterized in that, The elastomer includes a first state and a second state. When the elastomer is in the first state, at least a portion of the circumferential sidewall at the point of maximum diameter of the elastomer is spaced apart from the inner wall of the tube. When the elastomer is in the second state, at least a portion of the sidewall of the elastomer abuts against the inner wall of the tube in the circumferential direction to achieve sealing.

3. The catheter according to claim 1, characterized in that, The elastomer includes a skeleton and a flow-blocking membrane. The skeleton is connected to the adjusting member, and the flow-blocking membrane covers the sidewalls of the skeleton. The flow-blocking membrane and / or the skeleton are adapted to expand radially to both sides under pressure.

4. The catheter according to claim 3, characterized in that, The skeleton includes a first braided wire and a second braided wire, which intersect to form a mesh structure. The first braided wire and the second braided wire intersect and are movably connected.

5. The catheter according to claim 3, characterized in that, The frame includes multiple rod-shaped members, which are arranged in a circumferential array along the adjusting member, and the rod-shaped members are inclined relative to the axis of the adjusting member.

6. The catheter according to claim 3, characterized in that, The flow-blocking membrane is located radially outside the skeleton, and the flow-blocking membrane is spaced apart from the skeleton at least when the sealing member is in the second state.

7. The catheter according to claim 1, characterized in that, The elastomer includes a plurality of flow-blocking units, which are arranged around the adjusting member. The flow-blocking units are inclined relative to the axis of the adjusting member. Two adjacent flow-blocking units overlap at least partially in the circumferential direction and two adjacent flow-blocking units overlap in the radial direction.

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