Ginger-containing composition

Abstract

The present invention addresses the problem of providing a composition comprising ginger and lutein and / or crocetin, characterized in that denaturation of components in the composition due to time is suppressed, and also provides a method for suppressing denaturation of components in the composition, a method for producing the composition, and the like. The solution is a composition comprising: (A) one or more substances selected from the group consisting of Zinger Officinal Var.Rubra and an extract thereof, (B) one or more substances selected from the group consisting of the Zinger Officinal Var.Rubra and the extract thereof, and (C) one or more substances selected from the group consisting of the Zinger Officinal Var.Rubra and the extract thereof; and (B) one or more substances selected from the group consisting of lutein and crocetin.

Description

Technical Field

[0001] The present invention is a composition containing lutein and / or crocetin and containing red ginger. More specifically, the present invention relates to a composition containing lutein and / or crocetin, and red ginger (Zingiberofficinale var.Rubra) and / or an extract thereof. In addition, the present invention relates to a method for inhibiting discoloration of the composition components using the composition and a method for inhibiting the reduction of the amount of gingerol, and a method for producing the composition. Background Art

[0002] There are about 1,600 known species of plants in the Zingiberaceae family, and ginger (Zingiber officinale), ginger (Zingiber mioga), turmeric (Curcuma), etc. are used as spices and functional raw materials.

[0003] Ginger contains gingerol as a main component, and also contains shogaol, dehydrogingerdione, etc. Ginger is known to have various effects from these components, for example, it has been proposed to be used for improving indigestion, improving motion sickness, treating diabetes, analgesics, etc. (Patent Document 1).

[0004] On the other hand, lutein and crocetin are also known as functional raw materials for eyes and the like. Prior art literature Patent Literature

[0005] Patent Document 1: Japanese Patent Application Publication No. 2005-511641. Summary of the invention Problems to be solved by the invention

[0006] As a result of studying a composition comprising ginger, lutein and / or crocetin, the present inventors found that the components in the composition are denatured over time.

[0007] In this regard, the object of the present invention is to provide a composition comprising ginger, lutein and / or crocetin, wherein the time-dependent denaturation of the components in the composition is suppressed, and to provide a method for suppressing the denaturation of the components of the composition, a method for producing the composition, etc. Technical solutions to the problem

[0008] The present inventors have conducted intensive studies to solve the above problems and have found that a composition containing red ginger and / or an extract thereof and lutein and / or crocetin can suppress the time-dependent denaturation of the components in the composition, thereby completing the present invention.

[0009] That is, the present invention provides the following compositions and the like.

[0010] [1] A composition comprising: (A) one or more ingredients selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; and (B) one or more ingredients selected from the group consisting of lutein and crocetin.

[0011] [2] The composition according to [1], wherein the total content of the component (A) is 0.001% by mass to 50% by mass based on the total amount of the composition.

[0012] [3] The composition according to [1] or [2], wherein the content of the lutein is 0.001% by mass to 50% by mass relative to the total amount of the composition.

[0013] [4] The composition according to any one of [1] to [3], wherein the content of the crocetin is 0.001% by mass to 50% by mass relative to the total amount of the composition.

[0014] [5] The composition according to any one of [1] to [4], wherein the content of the lutein is 0.005 parts by mass to 200 parts by mass based on 1 part by mass of the total content of the component (A).

[0015] [6] The composition according to any one of [1] to [5], wherein the content of the crocetin is 0.005 to 50 parts by mass relative to 1 part by mass of the total content of the component (A).

[0016] [7] The composition according to any one of [1] to [6], which is in powder, granular or solid form.

[0017] [8] The composition according to any one of [1] to [6], which is in liquid or oily form.

[0018] [9] The composition according to any one of [1] to [8], which is a food composition.

[0019]

[10] The composition according to any one of [1] to [8], wherein discoloration of the composition is suppressed.

[0020]

[11] The composition according to any one of [1] to [8], wherein the reduction in the amount of gingerol in the composition is suppressed.

[0021] Furthermore, the present invention provides the following method for suppressing discoloration and the like.

[0022]

[12] A method for inhibiting discoloration of component (B), comprising the step of making component (A) contain component (B): component (A) is one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and its extracts; and component (B) is one or more selected from the group consisting of lutein and crocetin.

[0023] Furthermore, the present invention provides the following method for suppressing a decrease in the amount of gingerol, and the like.

[0024]

[13] A method for inhibiting the reduction of the amount of gingerol in component (A), comprising the step of making component (A) contain component (B): component (A) is one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; and component (B) is one or more selected from the group consisting of lutein and crocetin.

[0025] Furthermore, the present invention provides the following method for producing the composition and the like.

[0026]

[14] A method for producing a composition, wherein the composition is formed by inhibiting discoloration of component (B), the method comprising the step of making component (A) contain component (B): component (A) is one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; and component (B) is one or more selected from the group consisting of lutein and crocetin.

[0027]

[15] A method for producing a composition, wherein the composition is formed by inhibiting the reduction of the amount of gingerol in component (A), the method comprising the step of making component (A) contain component (B): component (A) is one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; and component (B) is one or more selected from the group consisting of lutein and crocetin. Advantageous Effects of the Invention

[0028] According to the composition of the present invention, it is possible to suppress a decrease in the amount of gingerol derived from red ginger and / or an extract thereof in the composition, and suppress discoloration of lutein and / or crocetin.

[0029] Furthermore, according to the method for inhibiting discoloration of the present invention, discoloration of lutein and / or crocetin in the composition can be inhibited.

[0030] Furthermore, according to the method for suppressing a decrease in the amount of gingerol of the present invention, a decrease in the amount of gingerol derived from red ginger and / or an extract thereof in the composition can be suppressed.

[0031] Furthermore, according to the method for producing the composition of the present invention, the composition can be easily obtained. DETAILED DESCRIPTION

[0032] [Composition] The composition of the present invention comprises: (A) one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; and (B) one or more selected from the group consisting of lutein and crocetin.

[0033] (Red ginger and / or its extract) The red ginger (red ginger) used in the present invention is a red ginger represented by a scientific name: Zingiber officinale var. Rubra, and includes, for example, red ginger.

[0034] Red ginger contains gingerol, shogaol, dehydrogingerdione, and the like as main components.

[0035] The part of red ginger involved is not particularly limited as long as the effects of the present invention are exerted, and examples thereof include: at least one selected from the group consisting of roots, stems, leaves, and flowers, preferably at least one selected from the group consisting of roots, stems, and leaves, more preferably at least one selected from the group consisting of roots and stems, and even more preferably rhizomes.

[0036] The extract of red ginger (red ginger extract) may be extracted by any method as long as the effects of the present invention are exhibited.

[0037] In the present specification, the extract of red ginger (red ginger extract) may be a crude extract extracted from the whole plant or essential parts (flowers, flower heads, flower buds, flower buds, flower spikes, leaves, branches, branches and leaves, rhizomes, root barks, roots, barks, fruits, pericarps, beans, seeds, etc.) of the plant, or may be a product that has been further refined, concentrated, synthesized, or a commercially available product. The method for obtaining the plant extract is not particularly limited, and a conventional extraction method, purification method, concentration method, synthesis method, drying and powdering method, etc. may be used.

[0038] As an example, the extract of red ginger is an extract obtained by immersing and extracting red ginger or a crushed product with water and / or an organic solvent and filtering the residue; a product obtained by removing the solvent from the extract; or these fine powders; or a product obtained by dissolving, dispersing, or diluting the extract or the product removed by using an appropriate solvent, etc., and commercial products can also be used. As an example of other extraction methods, the extract of red ginger can also be extracted after processing such as steaming the rhizome of red ginger. In addition, the periderm of the rhizome may be removed or used directly without removal.

[0039] In addition, as red ginger or an extract, for example, a mixture with cyclodextrin or the like can also be used as a formulation component.

[0040] In this specification, when using plant extracts (also known as plant extracts), in more detail, water (including hot water), methanol, ethanol, isopropanol, ethylene glycol, 1,3-butanediol, glycerol and other alcohols, esters such as ethyl acetate; ketones such as acetone, methyl ethyl ketone, nitriles such as acetonitrile; ethers such as diethyl ether and tetrahydrofuran; saturated hydrocarbons such as pentane, hexane, cyclopentane, cyclohexane, aromatic hydrocarbons such as toluene; halogenated hydrocarbons such as dichloromethane and chloroform; other organic solvents such as dimethylformamide and dimethyl sulfoxide (all of which can be water-containing) are used as extraction solvents, and can also be one or two arbitrary mixed solutions. Among these solvents, water, ethanol, 1,3-butanediol, or mixed solutions of these solvents are preferred. The extracts recorded in this specification can be obtained from various raw material companies, and these extracts are usually sold in the form of excipients in most cases, but there is no limitation. Hereinafter, the amount of the extract refers to the amount including the dry solid content and the excipient.

[0041] The extraction solvent of the red ginger extract is not limited as long as the effects of the present invention are exhibited, but water, ethanol, or hydrous ethanol is preferred, and hydrous ethanol is more preferred.

[0042] Examples of food ingredients containing red ginger or commercially available products of red ginger extracts include red fragrant ginger powder (Ryusendo), Hokka Hokka red ginger powder (MK Laboratories), red ginger extract P, red ginger extract-WSP, red ginger extract-PC, red ginger extract-WSPC, red ginger extract-LC (all from ORYZA Petrochemical Co., Ltd.), but are not limited to these commercially available products.

[0043] Although not limited, the content of [6]-gingerol and [6]-shogaol in the extract containing red ginger is preferably 3.0% by mass or more, and more preferably 6.0% by mass or more. Moreover, the content of tannin is preferably 0.5% by mass or more, and more preferably 1.5% by mass or more, in terms of proanthocyanidin B2. Moreover, although not limited, the content of cyclodextrin as an excipient is preferably 10% to 90%, more preferably 30% to 70% by mass, and further preferably 33% to 67% by mass.

[0044] The content of red ginger and / or its extract (the (A) component) is not particularly limited, but is preferably, for example, 0.01% by mass or more, 0.05% by mass or more, 0.1% by mass or more, 0.3% by mass or more, 0.5% by mass or more, 1% by mass or more, 3% by mass or more, 5% by mass or more, 10% by mass or more, or 20% by mass or more, and may be 90% by mass or less, 50% by mass or less, 25% by mass or less, 10% by mass or less, 5% by mass or less, 3% by mass or less, or 1% by mass or less, relative to the total amount of the composition.

[0045] In other embodiments, from the viewpoint of significantly exerting the effects of the present invention, when a red ginger extract is used, for example, the content of the red ginger extract can be 0.01% by mass or more, 0.05% by mass or more, 0.1% by mass or more, 0.3% by mass or more, 0.5% by mass or more, 1% by mass or more, 3% by mass or more, 5% by mass or more, 10% by mass or more, or 20% by mass or less, or 90% by mass or less, 50% by mass or less, 25% by mass or less, 10% by mass or less, 5% by mass or less, 3% by mass or less, or 1% by mass or less, relative to the total amount of the composition. The content of the red ginger extract may be, for example, 0.01 to 95% by mass, 0.01 to 70% by mass, 0.01 to 50% by mass, 0.01 to 30% by mass, 0.05 to 95% by mass, 0.05 to 70% by mass, 0.05 to 50% by mass, 0.05 to 30% by mass, 0.1 to 95% by mass, 0.1 to 70% by mass, 0.1 to 50% by mass, 0.1 to 30% by mass, 0.5 to 95% by mass, 0.5 to 70% by mass, 0.5 to 50% by mass, or 0.5 to 30% by mass.

[0046] In other embodiments, from the viewpoint of significantly exerting the effects of the present invention, when red ginger is used, for example, the content of red ginger can be 0.1% by mass or more, 0.5% by mass or more, 1% by mass or more, 3% by mass or more, 5% by mass or more, 10% by mass or more, 30% by mass or more, 50% by mass or more, or 99% by mass or less, 95% by mass or less, 90% by mass or less, 80% by mass or less, 70% by mass or less, or 60% by mass or less, relative to the total amount of the composition. The content of red ginger may be, for example, 0.1 to 99% by mass, 0.1 to 95% by mass, 0.1 to 90% by mass, 0.1 to 80% by mass, 0.5 to 99% by mass, 0.5 to 95% by mass, 0.5 to 90% by mass, 0.5 to 80% by mass, 1 to 99% by mass, 1 to 95% by mass, 1 to 90% by mass, 1 to 80% by mass, 3 to 99% by mass, 3 to 95% by mass, 3 to 90% by mass, or 3 to 80% by mass.

[0047] (Lutein and Crocetin) The lutein and crocetin (the component (B)) used in the present invention are not particularly limited, and known lutein and crocetin can be appropriately used.

[0048] For example, marigold extract or the like can be used as lutein.

[0049] Crocetin can be obtained, for example, by hydrolyzing crocin (digentiobiose ester of crocin), which is a yellow pigment of the carotenoid family. Crocin is contained in the fruit of gardenia, the dried product of the stigma of crocus, etc. In order to obtain the industrial raw material of crocin, it is preferable to use the fruit of gardenia.

[0050] Although the content of lutein is not particularly limited, relative to the total amount of the composition, for example, preferably more than 0.001 mass %, more than 0.005 mass %, more than 0.01 mass %, more than 0.02% mass %, more than 0.03 mass %, more than 0.05 mass %, more than 0.1 mass %, can also be less than 80 mass %, less than 70 mass %, less than 60 mass %, less than 50 mass %, less than 40 mass %, less than 30 mass %, less than 20 mass %. In addition, the content of lutein, for example, can also be more than 1 mass %, more than 5 mass %, 10 mass %. The content of lutein can also be 0.001 mass % to 80 mass %, 0.005 mass % to 70 mass %, 0.01 mass % to 60 mass %, 0.02 mass % to 50 mass %, 0.03 mass % to 40 mass %, 0.05 mass % to 30 mass %, 0.1 mass % to 20 mass %.

[0051] The content of lutein (oil raw material) relative to 1 part by mass of the total content of the component (A) may be, for example, 0.005 parts by mass or more, 0.05 parts by mass or more, 0.2 parts by mass or more, or 200 parts by mass or less, 40 parts by mass or less, or 10 parts by mass or less. In addition, the content of lutein (oil raw material) relative to 1 part by mass of the total content of the component (A) may be, for example, 0.005 to 200 parts by mass, 0.05 to 40 parts by mass, 0.2 to 10 parts by mass, etc. The content of lutein (oil raw material) may be, for example, 0.0005 to 200 parts by mass, 0.0005 to 100 parts by mass, 0.0005 to 40 parts by mass, 0.0005 to 10 parts by mass, 0.0005 to 2 parts by mass, 0.0005 to 1 part by mass, 0.001 to 200 parts by mass, 0.0005 to 100 parts by mass, 0.0005 to 2 ... 1 to 100 parts by mass, 0.001 to 40 parts by mass, 0.001 to 10 parts by mass, 0.001 to 2 parts by mass, 0.001 to 1 part by mass, 0.005 to 200 parts by mass, 0.005 to 100 parts by mass, 0.005 to 40 parts by mass, 0.005 to 10 parts by mass, 0.005 to 2 parts by mass, 0.005 to 100 parts by mass, 0.005 to 200 parts by mass, 0.005 to 100 parts by mass, 0.005 to 40 parts by mass, 0.005 to 100 parts by mass, 0.005 to 2 parts by mass, 0.005 to 100 parts by mass to 1 part by mass, 0.05 to 200 parts by mass, 0.05 to 100 parts by mass, 0.05 to 40 parts by mass, 0.05 to 10 parts by mass, 0.05 to 2 parts by mass, 0.05 to 1 part by mass, 0.2 to 200 parts by mass, 0.2 to 100 parts by mass, 0.2 to 40 parts by mass, 0.2 to 10 parts by mass, 0.2 to 2 parts by mass Part by mass, 0.2 to 1 part by mass, 1 to 200 parts by mass, 1 to 100 parts by mass, 1 to 40 parts by mass, 1 to 10 parts by mass, 1 to 2 parts by mass, 5 to 200 parts by mass, 5 to 100 parts by mass, 5 to 40 parts by mass, 5 to 10 parts by mass, 10 to 200 parts by mass, 10 to 100 parts by mass, 10 to 40 parts by mass, and the like.

[0052] The content of lutein (powdered raw material) relative to 1 part by mass of the total content of the component (A) may be, for example, 0.005 parts by mass or more, 0.05 parts by mass or more, 0.2 parts by mass or more, or 200 parts by mass or less, 40 parts by mass or less, or 10 parts by mass or less. In addition, the content of lutein (powdered raw material) relative to 1 part by mass of the total content of the component (A) may be, for example, 0.005 to 200 parts by mass, 0.05 to 40 parts by mass, 0.2 to 10 parts by mass, etc. The content of lutein (powdered raw material) may be, for example, 0.0005 to 200 parts by mass, 0.0005 to 100 parts by mass, 0.0005 to 40 parts by mass, 0.0005 to 10 parts by mass, 0.0005 to 2 parts by mass, 0.0005 to 1 part by mass, 0.001 to 200 parts by mass, 0.0005 to 100 parts by mass, 0.0005 ... 0.01 to 100 parts by mass, 0.001 to 40 parts by mass, 0.001 to 10 parts by mass, 0.001 to 2 parts by mass, 0.001 to 1 part by mass, 0.005 to 200 parts by mass, 0.005 to 100 parts by mass, 0.005 to 40 parts by mass, 0.005 to 10 parts by mass, 0.005 to 2 parts by mass, 0.005 to 100 parts by mass, 0.005 to 200 parts by mass, 0.005 to 100 parts by mass, 0.005 to 40 parts by mass, 0.005 to 100 parts by mass, 0.005 to 2 parts by mass, 0.005 to 100 parts by mass to 1 part by mass, 0.05 to 200 parts by mass, 0.05 to 100 parts by mass, 0.05 to 40 parts by mass, 0.05 to 10 parts by mass, 0.05 to 2 parts by mass, 0.05 to 1 part by mass, 0.2 to 200 parts by mass, 0.2 to 100 parts by mass, 0.2 to 40 parts by mass, 0.2 to 10 parts by mass, 0.2 to 2 parts by mass Part by mass, 0.2 to 1 part by mass, 1 to 200 parts by mass, 1 to 100 parts by mass, 1 to 40 parts by mass, 1 to 10 parts by mass, 1 to 2 parts by mass, 5 to 200 parts by mass, 5 to 100 parts by mass, 5 to 40 parts by mass, 5 to 10 parts by mass, 10 to 200 parts by mass, 10 to 100 parts by mass, 10 to 40 parts by mass, and the like.

[0053] The content of lutein as a component, relative to 1 part by mass of the total content of the component (A), may be, for example, 0.0005 parts by mass or more, 0.001 parts by mass or more, 0.005 parts by mass or more, 0.05 parts by mass or more, 0.2 parts by mass or more, or 1 part by mass or more, or may be 200 parts by mass or less, 100 parts by mass or less, 40 parts by mass or less, 10 parts by mass or less, 2 parts by mass or less, or 1 part by mass or less. In addition, the content of lutein as a component, relative to 1 part by mass of the total content of the component (A), may be, for example, 0.0005 to 200 parts by mass, 0.0005 to 100 parts by mass, 0.0005 to 40 parts by mass, 0.0005 to 10 parts by mass, 0.0005 to 2 parts by mass, 0.0005 to 1 part by mass, 0.001 to 200 parts by mass, 0.00 1 to 100 parts by mass, 0.001 to 40 parts by mass, 0.001 to 10 parts by mass, 0.001 to 2 parts by mass, 0.001 to 1 part by mass, 0.005 to 200 parts by mass, 0.005 to 100 parts by mass, 0.005 to 40 parts by mass, 0.005 to 10 parts by mass, 0.005 to 2 parts by mass, 0.005 to 1 part by mass, 0.05 to 200 parts by mass, 0.05 to 100 parts by mass, 0.05 to 40 parts by mass, 0.05 to 10 parts by mass, 0.05 to 2 parts by mass, 0.05 to 1 part by mass, 0.2 to 200 parts by mass, 0.2 to 100 parts by mass, 0.2 to 40 parts by mass, 0.2 to 10 parts by mass, 0.2 to 2 parts by mass , 0.2 to 1 part by mass, 1 to 200 parts by mass, 1 to 100 parts by mass, 1 to 40 parts by mass, 1 to 10 parts by mass, 1 to 2 parts by mass, 5 to 200 parts by mass, 5 to 100 parts by mass, 5 to 40 parts by mass, 5 to 10 parts by mass, 10 to 200 parts by mass, 10 to 100 parts by mass, 10 to 40 parts by mass, and the like.

[0054] The content of crocetin is not particularly limited, but it can be, for example, 0.05% by mass or more, 0.08% by mass or more, 0.1% by mass or more, 0.3% by mass or more, 0.5% by mass or more, 0.8% by mass or more, 1% by mass or more, or 100% by mass or less, 80% by mass or less, 50% by mass or less, 40% by mass or less, 30% by mass or less, 20% by mass or less, 15% by mass or less, or 10% by mass or less, relative to the total amount of the composition.

[0055] The content of crocetin relative to 1 part by mass of the content of the component (A) may be, for example, 0.005 parts by mass or more, 0.03 parts by mass or more, 0.1 parts by mass or more, or 50 parts by mass or less, 7 parts by mass or less, or 2 parts by mass or less. In addition, the content of crocetin relative to 1 part by mass of the content of the component (A) may be, for example, 0.005 to 50 parts by mass, 0.03 to 7 parts by mass, 0.1 to 2 parts by mass, etc. In addition, the content of crocetin relative to the content of the component (A) 1 mass part, for example, can also be 0.0005 mass part to 200 mass parts, 0.0005 mass part to 100 mass parts, 0.0005 mass part to 40 mass parts, 0.0005 mass part to 10 mass parts, 0.0005 mass part to 2 mass parts, 0.0005 mass part to 1 mass part, 0.001 mass part to 200 mass parts, 0.001 mass part to 100 mass parts, 0.0005 mass part to 200 mass parts, 0.001 mass part to 100 mass parts, 0.0005 mass part to 200 mass parts, 0.0005 mass part to 1 ... 0.001 to 100 parts by mass, 0.001 to 40 parts by mass, 0.001 to 10 parts by mass, 0.001 to 2 parts by mass, 0.001 to 1 part by mass, 0.005 to 200 parts by mass, 0.005 to 100 parts by mass, 0.005 to 40 parts by mass, 0.005 to 10 parts by mass, 0.005 to 2 parts by mass, 0.005 to 1 part by mass parts by mass, 0.05 parts by mass to 200 parts by mass, 0.05 parts by mass to 100 parts by mass, 0.05 parts by mass to 40 parts by mass, 0.05 parts by mass to 10 parts by mass, 0.05 parts by mass to 2 parts by mass, 0.05 parts by mass to 1 part by mass, 0.2 parts by mass to 200 parts by mass, 0.2 parts by mass to 100 parts by mass, 0.2 parts by mass to 40 parts by mass, 0.2 parts by mass to 10 parts by mass, 0.2 parts by mass to 2 parts by mass, 0.2 to 1 part by mass, 1 to 200 parts by mass, 1 to 100 parts by mass, 1 to 40 parts by mass, 1 to 10 parts by mass, 1 to 2 parts by mass, 5 to 200 parts by mass, 5 to 100 parts by mass, 5 to 40 parts by mass, 5 to 10 parts by mass, 10 to 200 parts by mass, 10 to 100 parts by mass, 10 to 40 parts by mass, and the like.

[0056] The daily oral intake or dosage of component (A) for an adult is, for example, preferably 0.5 mg / day or more, more preferably 1 mg / day or more, further preferably 3 mg / day or more, particularly preferably 5 mg / day or more, and most preferably 10 mg / day or more. The daily oral intake or dosage of ginger and / or its extract for an adult is, for example, preferably 500 mg / day or less, more preferably 200 mg / day or less, further preferably 100 mg / day or less, and particularly preferably 50 mg / day or less.

[0057] The daily intake or dosage of lutein for adults is preferably 1 mg / day or more, more preferably 5 mg / day or more, and particularly preferably 10 mg / day or more. The daily oral intake or dosage of lutein for adults is, for example, preferably 200 mg / day or less, more preferably 100 mg / day or less, and further preferably 50 mg / day or less.

[0058] The daily intake or dosage of crocetin for adults is preferably 1 mg / day or more, more preferably 3 mg / day or more, and particularly preferably 5 mg / day or more. The daily oral intake or dosage of crocetin for adults is, for example, preferably 50 mg / day or less, more preferably 20 mg / day or less, and particularly preferably 10 mg / day or less.

[0059] (Composition) The composition includes the component (A) and the component (B).

[0060] The component (A) may be one or more selected from the group consisting of red ginger and extracts thereof. For example, red ginger of a plurality of qualities and / or red ginger extracts of a plurality of qualities may be used in combination.

[0061] The component (B) may be at least one selected from the group consisting of lutein and crocetin. For example, lutein of a plurality of qualities and / or crocetin of a plurality of qualities may be used in combination.

[0062] The composition may be formulated with various components, for example, including zeaxanthin, astaxanthin, anthocyanidin, DHA, EPA, and the like.

[0063] When zeaxanthin, astaxanthin and anthocyanidins are formulated, their contents may be, for example, 0.0005 mass parts or more, 0.001 mass parts or more, 0.005 mass parts or more, 0.05 mass parts or more, 0.2 mass parts or more, or may be 200 mass parts or less, 100 mass parts or less, 40 mass parts or less, 10 mass parts or less, 2 mass parts or less, or 1 mass part or less, respectively, relative to 1 mass part of the total content of the component (A). In addition, when zeaxanthin, astaxanthin, and anthocyanidin are formulated, the content of these formulated components, relative to 1 part by mass of the total content of the component (A), can be, for example, 0.0005 to 200 parts by mass, 0.0005 to 100 parts by mass, 0.0005 to 40 parts by mass, 0.0005 to 10 parts by mass, 0.0005 to 2 parts by mass, 0.0005 to 1 part by mass, 0.001 to 100 parts by mass, 0.0005 to 2 parts by mass, 0.0005 to 1 part by mass, 0.001 to 100 parts by mass, 0.0005 to 20 parts by mass, 0.0005 to 10 ... 0.001 to 100 parts by mass, 0.001 to 40 parts by mass, 0.001 to 10 parts by mass, 0.001 to 2 parts by mass, 0.001 to 1 part by mass, 0.005 to 200 parts by mass, 0.005 to 100 parts by mass, 0.005 to 40 parts by mass, 0.005 to 10 parts by mass, 0.005 to 2 parts by mass, 0.005 to 1 part by mass, 0.05 to 200 parts by mass, 0.05 to 100 parts by mass, 0.05 to 40 parts by mass, 0.05 to 10 parts by mass, 0.05 to 2 parts by mass, 0.05 to 1 part by mass, 0.2 to 200 parts by mass, 0.2 to 100 parts by mass, 0.2 to 40 parts by mass, 0.2 to 10 parts by mass, 0.2 to 200 parts by mass, 0.2 to 100 parts by mass, 0.2 to 40 parts by mass, 0.2 to 10 parts by mass, 0.2 to 200 parts by mass 1 to 2 parts by mass, 0.2 to 1 part by mass, 1 to 200 parts by mass, 1 to 100 parts by mass, 1 to 40 parts by mass, 1 to 10 parts by mass, 1 to 2 parts by mass, 5 to 200 parts by mass, 5 to 100 parts by mass, 5 to 40 parts by mass, 5 to 10 parts by mass, 10 to 200 parts by mass, 10 to 100 parts by mass, 10 to 40 parts by mass, and the like.

[0064] Various additives may be formulated into the composition, for example. Examples of the additives include antioxidants, pigments, spices, seasonings, sweeteners, acidulants, pH adjusters, quality stabilizers, preservatives, etc. These additives may be used alone or in combination of two or more.

[0065] The composition may contain a known solvent, powder, etc. as necessary.

[0066] The solvent is not particularly limited, and examples thereof include water, alcohol, hydrous alcohol, fats and oils, etc. In addition, a known solvent used for food applications is preferred.

[0067] The fat (oil) is not particularly limited, and examples thereof include: safflower oil (safflower oil), grape seed oil, sunflower oil (sunflower oil), olive oil, corn oil, sesame oil, soybean oil, soybean germ oil, rapeseed oil, high oleic rapeseed oil, perilla oil, linseed oil, peanut oil, safflower oil, cottonseed oil, walnut oil, wheat germ oil, fish oil (EPA·DHA), palm oil, coconut oil, cocoa butter and other vegetable oils, beef tallow, lard, chicken fat, milk fat, algae oil and other animal oils, in addition to these, synthetic oils such as diglycerides and medium-chain fatty acid triglycerides, separated oils, transesterified oils, hydrogenated oils and the like can also be mentioned. Preferred oils and fats include vegetable oils, among which safflower oil (safflower oil), grape seed oil, sunflower oil (sunflower oil), olive oil, corn oil, sesame oil, soybean oil, rapeseed oil, and perilla oil are preferred, safflower oil (safflower oil), grape seed oil, sunflower oil (sunflower oil), olive oil, and corn oil are more preferred, and safflower oil (safflower oil) is particularly preferred.

[0068] The powder is not particularly limited, and examples thereof include sugars such as sucrose and lactose, etc. In addition, known powders used for food applications are preferred.

[0069] The shape of the composition is not particularly limited, and may be, for example, powder, granules, solid, liquid, or oily.

[0070] According to the composition of the present invention, discoloration of lutein and / or crocetin in the composition can be suppressed. Therefore, the composition can be used as a composition for suppressing discoloration of the composition.

[0071] In the present invention, the terms "inhibit discoloration" and "inhibit discoloration" include: preventing discoloration, reducing the degree of discoloration, and maintaining no discoloration.

[0072] Furthermore, according to the composition of the present invention, the amount of gingerol in the composition can be suppressed from decreasing. Therefore, the composition can be used as a composition in which the amount of gingerol in the composition is suppressed from decreasing.

[0073] In the present invention, "suppressing a decrease in gingerol amount" and "suppressing a decrease in gingerol amount" include preventing a decrease in gingerol amount, reducing the degree of a decrease in gingerol amount, maintaining a gingerol amount from decreasing, and the like.

[0074] (Food composition) The composition of the present invention can be suitably used as a food composition, for example, a health food, a functional food, a health supplement food, a nutritional functional food, a special purpose food, a food for specified insurance use, or a general food.

[0075] Examples of the form of the food composition include liquid forms such as juice, soft drinks, health drinks, and tea; solid forms such as biscuits, tablets, granules, powders, and capsules; and semi-fluid forms such as pastes, jellies, soups, seasonings, and salad dressings.

[0076] Specifically, examples include: rice; various breads including pizza, scones, pancakes, bagels, focaccia, and croissants; various noodles including soba, udon, vermicelli, Chinese noodles, instant noodles, and cup noodles; various pastas including spaghetti, macaroni, penne, and lasagna; beverages such as soft drinks, carbonated drinks, nutritional drinks, fruit juice drinks, lactic acid drinks, and sports drinks; curry cubes (curry roux), stews, and various soups; ice cream, sherbet, shaved ice and other ice products; desserts such as maltose, cookies, candy, chewing gum, chocolate, ingot candy, snack desserts, biscuits, jelly, jam, fresh cream, and other baked desserts; processed seafood / livestock foods such as fish cakes, half slices (Japanese fish paste processed products), ham, and sausages; dairy products such as processed milk and fermented milk; salad oil, frying oil, margarine, mayonnaise, shortening, whipped cream, salad dressing and other fats and fat-processed foods; seasonings such as sauces, salad dressings, miso, soy sauce, and sauces; soups, stews, salads, side dishes, rice seasonings, pickles; and various other forms of health / nutritional supplementary foods, etc.

[0077] Furthermore, the food composition of the present invention or the food that can be provided in a form containing the food composition thereof, for example, also includes: nutritional supplements (powders, granules, soft capsules, hard capsules, tablets, chewable tablets, rapidly disintegrating tablets, syrups, liquids, etc.).

[0078] Furthermore, feed for animals such as pets may contain the food composition of the present invention.

[0079] Additives may be added to the food composition or the food as necessary. Examples of such additives include glucose, fructose, sucrose, maltose, sorbitol, stevioside, rubusoside, corn syrup, lactose, mannitol, dextrin, citric acid, sodium citrate, tartaric acid, malic acid, succinic acid, lactic acid, L-ascorbic acid, dl-α-tocopherol, sodium isoascorbate, glycerol, propylene glycol, glycerol fatty acid esters, polyglycerol fatty acid esters, sucrose fatty acid esters, sorbitan fatty acid esters, gum arabic, carrageenan, casein, gelatin, pectin, agar, vitamin C, vitamin B, vitamin E, niacinamide, calcium pantothenate, amino acids, calcium salts, surfactants, pigments, flavors, preservatives, and the like.

[0080] [Discoloration suppression method] The method for inhibiting discoloration of the component (B) of the present invention comprises the step of causing the component (A) to contain the component (B): The component (A) is one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; and the component (B) is one or more selected from the group consisting of lutein and crocetin.

[0081] In the discoloration suppression method, the step of making the component (A) contain the component (B) is not particularly limited, as long as both the component (A) and the component (B) are contained. The step may be, for example, a method of adding the component (A) to the component (B); a method of adding the component (B) to the component (A); or a method of adding the component (A) and the component (B) together to other substances such as a solvent.

[0082] By including the above step, discoloration of lutein and / or crocetin in the above composition can be suppressed.

[0083] [Method for inhibiting the decrease in gingerol content] The method for inhibiting the reduction of the amount of gingerol in the component (A) of the present invention comprises the step of making the component (A) contain the component (B): the component (A) is one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and its extracts; the component (B) is one or more selected from the group consisting of lutein and crocetin.

[0084] In the method for inhibiting the reduction of the amount of gingerol, the step of making the component (A) contain the component (B) is not particularly limited, as long as both the component (A) and the component (B) are contained. The step may be, for example, a method of adding the component (A) to the component (B); a method of adding the component (B) to the component (A); or a method of adding the component (A) and the component (B) together to other substances such as a solvent.

[0085] By including the above step, the amount of gingerol derived from red ginger and / or its extract in the above composition can be suppressed from decreasing. The mechanism of action for the above effect is not clear, but it is presumed to be related to the following phenomenon: the direct influence of the external environment on the component (A) is reduced through the appropriate interaction between the component (A) and the component (B), but the scope of the present invention is not limited to the above mechanism.

[0086] [Method for producing composition] As a method for producing the composition of the present invention, for example, a method can be used that includes the step of making component (A) contain component (B): the component (A) is one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; the component (B) is one or more selected from the group consisting of lutein and crocetin.

[0087] In the method for preparing the composition, the step of making the component (A) contain the component (B) is not particularly limited, as long as both the component (A) and the component (B) are contained. The step may be, for example, a method of adding the component (A) to the component (B); a method of adding the component (B) to the component (A); or a method of adding the component (A) and the component (B) together to other substances such as a solvent.

[0088] In addition, as a method for producing a composition obtained by suppressing discoloration of the component (B), there is exemplified a method including a step of making the component (A) contain the component (B).

[0089] Furthermore, as a method for producing a composition obtained by suppressing a decrease in the amount of gingerol in the component (A), there can be mentioned a method including a step of making the component (A) contain the component (B). [Example]

[0090] Next, the present invention will be specifically described with reference to Examples, but the present invention is not limited to the following Examples. In the Examples, when no unit is particularly indicated, it indicates part by mass or mass %.

[0091] [Example 1 to Example 6, Comparative Example 1 to Comparative Example 10] Each composition was prepared according to the formulation described in each table. The numerical values ​​in Table 1 are the formulation amounts of the components in Table 1. In addition, safflower oil was used as the oil in the table. Red ginger: Red ginger extract-P, ORYZA Petrochemical Co., Ltd. (mixed with 50% red ginger extract and 50% cyclodextrin) Ginger extract: GINGER EXTRACT POWER15%, Bio Actives Japan Co., Ltd. Lutein (oil): FloraGLO (registered trademark) Lutein 20%, Zeaxanthin 4% SAF, DSM Co., Ltd. Lutein (powder): FloraGLO (registered trademark) Lutein 10%, Zeaxanthin 0.6% SG-VG granules, DSM Co., Ltd. Crocetin (powder): Crovit P, Riken Vitamin Co., Ltd.

[0092] Furthermore, the color change of each of the prepared compositions was performed in the following manner.

[0093] (Color change measurement method) The powder or oil raw materials shown in each table were weighed, mixed, placed in a bottle, and then covered to prepare each sample. After measuring the color difference with a spectrophotometer (CM-5: manufactured by Konica Minolta Co., Ltd.), aging was performed according to the following aging conditions, and then the color difference was measured again in the same manner. Aging conditions: 1 week at 60°C The color difference (ΔE*ab) was measured before and after aging to determine the color difference change suppression rate. The color difference change suppression rate is calculated by the following formula. Chromatic difference change inhibition rate (%) = 100 × [{(ΔE*ab of the comparative example in which only lutein or crocetin and oil were prepared) - (ΔE*ab of the example in which red ginger or ginger was added)} / (ΔE*ab of the comparative example in which only lutein or crocetin and oil were prepared)]

[0094] Tables 1 to 6 show the measurement results of the color changes of the above-mentioned compositions.

[0095] [Table 1] Table 1

[0096] [Table 2] Table 2

[0097] [Table 3] Table 3

[0098] [Table 4] Table 4

[0099] [Table 5] Table 5

[0100] [Table 6] Table 6

[0101] As shown in Tables 1 to 6, when the composition of the Example containing red ginger was used, the discoloration of the composition was suppressed. In addition, the ginger extract did not show the discoloration suppression effect like red ginger.

[0102] [Examples 7 to 9, Comparative Example 11] According to the formulation described in Table 7, each composition was prepared.

[0103] The gingerol content of each of the prepared compositions was measured in the following manner.

[0104] (Determination of gingerol content) Each sample was prepared by weighing and mixing the powder or oil raw materials shown in Table 7, placing them in a bottle and then capping it. Storage conditions: 60℃ constant temperature bath for 1 week The gingerol content was quantified before and after aging storage, and the gingerol reduction rate was calculated from the gingerol residual rate before and after aging (100×gingerol content after aging / gingerol content before aging [%]), and the gingerol reduction inhibition rate was further calculated. Gingerol reduction rate = 100 - gingerol residual rate [%] Gingerol reduction inhibition rate = 100 × (gingerol reduction rate of Comparative Example 11 - gingerol reduction rate of each test example) / gingerol reduction rate of Comparative Example 11 [%]

[0105] Table 7 shows the measurement results of the gingerol content of each composition.

[0106] [Table 7] Table 7

[0107] As shown in Table 7, when the composition of the examples containing lutein or crocetin was used, the stability of gingerol in the composition was improved.

[0108] [Manufacturing Examples 1 to 20] Compositions in various dosage forms can be prepared according to the formulations described in Tables 8 and 9.

[0109] [Table 8] (mg / day)

[0110] [Table 9] (mg / day)

Claims

1. A ginger-containing composition comprising: (A) one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; and (B) one or more selected from the group consisting of lutein and crocetin.

2. The composition according to claim 1, characterized in that The total content of the component (A) is 0.001% by mass to 50% by mass based on the total amount of the composition.

3. The composition according to claim 1, characterized in that The content of the lutein is 0.001% by mass to 50% by mass relative to the total amount of the composition.

4. The composition according to claim 1, characterized in that The content of the crocetin is 0.001% by mass to 50% by mass relative to the total amount of the composition.

5. The composition according to claim 1, characterized in that The content of the lutein is 0.005 to 200 parts by mass based on 1 part by mass of the total content of the component (A).

6. The composition according to claim 1, characterized in that The content of the crocetin is 0.005 to 50 parts by mass based on 1 part by mass of the total content of the component (A).

7. The composition according to any one of claims 1 to 6, which is in powder, granular or solid form.

8. The composition according to any one of claims 1 to 6, which is in liquid or oily form.

9. The composition according to any one of claims 1 to 6, which is a food composition.

10. The composition according to any one of claims 1 to 6, which is a composition constituted by suppressing discoloration of the composition.

11. The composition according to any one of claims 1 to 6, which is a composition constituted by suppressing a decrease in the amount of gingerol in the composition.

12. A method for inhibiting discoloration of a component (B), comprising the step of causing a component (A) to contain the component (B): The component (A) is one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; The component (B) is at least one selected from the group consisting of lutein and crocetin.

13. A method for inhibiting the reduction of the amount of gingerol in component (A), comprising the step of causing component (B) to contain component (A): The component (A) is one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; The component (B) is at least one selected from the group consisting of lutein and crocetin.

14. A method for producing a composition, wherein the composition is a composition formed by suppressing discoloration of a component (B), the method comprising the step of causing a component (A) to contain the component (B): The component (A) is one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; The component (B) is at least one selected from the group consisting of lutein and crocetin.

15. A method for producing a composition, wherein the composition is a composition formed by suppressing the reduction of the amount of gingerol in component (A), the method comprising the step of causing component (B) to be contained in component (A): The component (A) is one or more selected from the group consisting of red ginger (Zingiber officinale var. Rubra) and extracts thereof; The component (B) is at least one selected from the group consisting of lutein and crocetin.

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