Gamma-aminobutyric acid beverage for improving sleep and preparation method thereof

Abstract

The invention discloses a gamma-aminobutyric acid beverage capable of improving sleep and a preparation method of the gamma-aminobutyric acid beverage. The gamma-aminobutyric acid beverage is prepared from the following raw materials in parts by weight: 2 to 6 parts of erythritol, 0.83 to 2.52 parts of resistant dextrin, 0.4 to 1 part of polydextrose, 1.8 to 2.2 parts of lemon juice, 0.15 to 0.28 part of L-theanine, 0.21 to 0.55 part of chamomile extract, 0.02 to 0.06 part of passion flower powder, 0.15 to 0.28 part of gamma-aminobutyric acid, 0.4 to 1 part of bone collagen peptide, 0.03 to 0.1 part of sodium hyaluronate, 0.12 to 0.43 part of pectin and 45 to 50 parts of water. By adding the L-theanine, the gamma-aminobutyric acid, the chamomile extract, the passion flower powder and the bone collagen peptide and supplementing with nutrient substances such as the lemon juice, the sodium hyaluronate, the pectin and the erythritol, the effects of calming and sleeping, relieving anxiety, relieving physical fatigue and enhancing the immunity of the organism can be achieved, and through the combined action of all the raw materials, the health-care food has a good health-care effect. The prepared gamma-aminobutyric acid beverage capable of improving sleep has an excellent function of improving sleep, and is good and quick in effect.

Description

Technical Field

[0001] The invention relates to the technical field of food processing, and in particular to a gamma-aminobutyric acid drink for improving sleep and a preparation method thereof. Background Art

[0002] Long-term insomnia will have a serious negative impact on normal life and work, and may even lead to serious accidents. Insomnia can usually lead to anxiety, depression, and irritability. Patients may be prone to listlessness, sadness, lack of interest in life, more pessimistic than usual, or want to cry, or even feel that life is meaningless, or even want to commit suicide; sleep may be more prone to anxiety, or nervousness, restlessness, and even panic attacks, that is, sudden strong discomfort or panic, dizziness, suffocation and difficulty breathing. Insomnia may also cause patients to have reduced work and study ability, memory loss, inability to concentrate, and decreased brain function. Insomnia can be divided into many types according to clinical manifestations and causes, such as difficulty falling asleep, difficulty maintaining sleep, early awakening, and mixed types. The causes of its onset are complex and diverse, including psychological factors, physiological factors, environmental factors, and lifestyle habits. High-risk groups mainly include the elderly, women (especially menopausal women), those with a history of mental illness or family history, and those who have been under high-pressure work for a long time. Although insomnia itself does not directly cause death, long-term insomnia can significantly increase the risk of chronic diseases such as cardiovascular disease and diabetes, and indirectly affect the quality of life and life expectancy.

[0003] The clinical symptoms of insomnia are mainly difficulty falling asleep, frequent awakenings at night, early awakening and difficulty falling asleep again, and feeling tired and inattentive after waking up. Long-term insomnia may also cause complications such as memory loss, mood swings, and decreased immunity.

[0004] Long-term insomnia is indeed a problem that bothers ordinary people, because it may have a serious impact on their life and work.

[0005] First, the impact of insomnia on emotions. Patients with long-term insomnia may experience changes in emotions, such as anxiety, irritability, depression and other related emotional symptoms, so it is very harmful to the human body.

[0006] Second, insomnia can lead to endocrine disorders. Endocrine disorders will cause some symptoms, including high blood sugar, high blood pressure, high blood lipids or acne, obesity, dyslipidemia, etc., so long-term insomnia has a very serious impact on endocrine.

[0007] Third, patients with long-term insomnia will also suffer from some nervous system diseases. For example, patients will often experience dizziness, headaches, and even nausea, vomiting and some other neurological systemic diseases. Therefore, through the above analysis, insomnia has many harmful effects on the human body.

[0008] Currently, there are many drinks on the market that can improve sleep, but most of the existing products have poor improvement effects, contain preservatives, sucrose, melatonin and other substances that have side effects on the human body, are prone to recurrence and dependence.

[0009] In view of this, the present invention is proposed. Summary of the invention

[0010] The object of the present invention is to provide a γ-aminobutyric acid beverage for improving sleep and a preparation method thereof. The γ-aminobutyric acid beverage for improving sleep has excellent sleep-improving function through the selection of various raw materials, and the effect is good and the effect is fast.

[0011] In order to achieve the above-mentioned purpose of the present invention, the following technical solutions are particularly adopted:

[0012] The first aspect of the present invention provides a γ-aminobutyric acid beverage for improving sleep, wherein the γ-aminobutyric acid beverage for improving sleep comprises the following raw materials in parts by weight:

[0013] 2-6 parts of erythritol, 0.83-2.52 parts of resistant dextrin, 0.4-1 parts of polydextrose, 1.8-2.2 parts of lemon juice, 0.15-0.28 parts of L-theanine, 0.21-0.55 parts of chamomile extract, 0.02-0.06 parts of passionflower powder, 0.15-0.28 parts of gamma-aminobutyric acid, 0.4-1 parts of collagen peptide, 0.03-0.1 parts of sodium hyaluronate, 0.12-0.43 parts of pectin and 45-50 parts of water.

[0014] In the present invention, gamma-aminobutyric acid (GABA) is a natural active ingredient widely distributed in animals and plants. Plants such as leguminous plants, ginseng plants, Chinese herbal medicines, etc. contain gamma-aminobutyric acid in their seeds, rhizomes and tissue fluids. In animals, gamma-aminobutyric acid is almost exclusively found in nerve tissue. Effects of gamma-aminobutyric acid: Mental state: anti-anxiety, anti-depression, stress relief, mood regulation, relaxation of tense spirit, relief of tension, and mental stability. Improve sleep: promote the brain to fall asleep as soon as possible, and enter a deep sleep state as soon as possible, significantly improve sleep quality, especially for insomniacs with wild thoughts and an excited brain; Brain vitality: improve blood flow to the brain, increase oxygen supply to the brain, and restore brain cell function; Lower blood pressure: promote vasodilation and have a blood pressure lowering effect.

[0015] Theanine is an important component that makes tea fresh. Theanine has the effects of clearing away heat, calming and soothing the mood. The effects of theanine in tea: It affects the changes in neurotransmitters in the brain and enhances memory. Theanine has a sedative effect and may prevent neurological disorders, insomnia, premenstrual syndrome, etc. Theanine can protect nerve cells and may be used to prevent and treat diseases such as cerebral embolism, cerebral hemorrhage, cerebral stroke, cerebral ischemia and Alzheimer's disease. Theanine can also improve immunity.

[0016] Passion fruit is rich in protein, fat, reducing sugar, multiple vitamins and up to 165 compounds such as phosphorus, calcium, iron, potassium, and 17 essential amino acids for the human body. It has high nutritional value. The vitamin content is 1345 (1 U / 100G), which is an effective anti-cancer ingredient. The niacin content is 1.7 mg / 100G, which plays a positive role in preventing cardiovascular diseases. The roots, stems and leaves of passion fruit can be used as medicine, which has the effects of anti-inflammatory, analgesic, blood circulation, strengthening the body, lowering lipids and blood pressure.

[0017] Resistant dextrin: Resistant dextrin is a white to light yellow powder. It is a water-soluble dietary fiber made from corn starch through a certain degree of hydrolysis, polymerization, separation and other steps. It has low calories. Resistant dextrin has the characteristics of resisting the action of digestive enzymes. Since it will not be digested and absorbed in the digestive tract, it can directly enter the large intestine. Therefore, it plays various physiological roles of dietary fiber. Because of its high digestion tolerance, low glycemic index, low insulin index, low calories, easy solubility and other characteristics, it can play the role of lowering blood sugar, lowering blood lipids and maintaining the intestines.

[0018] Polydextrose: Polydextrose is a water-soluble dietary fiber. It is white or off-white solid particles, easily soluble in water, and has no special smell. It is a food component with health functions and can supplement the water-soluble dietary fiber required by the human body. Polydextrose can absorb water in the intestines, increase stool volume, promote defecation, and prevent constipation. It can also promote the production of lactobacillus or bifidobacteria in the intestines, which is beneficial for regulating intestinal flora. It can also reduce the sensitivity of tissue terminals to insulin and effectively lower blood sugar. This substance can also promote the absorption of minerals by the intestines.

[0019] Sodium hyaluronate: replenishes moisture, keeps skin muscle cells active, accelerates facial skin metabolism, increases skin elasticity, and prevents skin cracking and wrinkles. It can promote the supply of nutrients to the skin, promote the excretion of waste, and prevent skin aging. It can repair skin damage caused by ultraviolet rays.

[0020] Collagen peptide: Collagen peptide powder is helpful to improve anxiety and neurasthenia. It can improve sleep and sleep quality. It can also promote bone development, nourish the skin, and resist aging. It can improve immunity and promote physical health.

[0021] Erythritol: Almost no calories: Calories can be said to be a very important indicator of weight gain. If you want to lose weight, you should reduce your calorie intake. Erythritol has very low calories. It does not affect blood sugar: It will not increase the level of glucose or insulin in the body. Anti-oxidation: The antioxidant effect of erythritol is quite good, because antioxidants can remove harmful free radicals in the body, and can also prevent diseases such as vascular damage caused by high blood sugar. After taking it, it can make the skin better. It will not cause tooth decay: Too much sugar intake will cause tooth decay, so taking erythritol can reduce the occurrence of tooth decay, because erythritol has been shown through certain experimental studies to be a lower sugar content ingredient and will not cause tooth decay.

[0022] Preferably, the γ-aminobutyric acid beverage for improving sleep comprises the following raw materials in parts by weight:

[0023] 4 parts of erythritol, 1.2 parts of resistant dextrin, 0.8 parts of polydextrose, 2 parts of lemon juice, 0.2 parts of L-theanine, 0.4 parts of chamomile extract, 0.04 parts of passion fruit powder, 0.2 parts of gamma-aminobutyric acid, 0.8 parts of collagen peptide, 0.06 parts of sodium hyaluronate, 0.3 parts of pectin and 50 parts of water.

[0024] The second aspect of the present invention provides a method for preparing the above-mentioned γ-aminobutyric acid beverage for improving sleep, the preparation method comprising the following steps:

[0025] (a) weighing each raw material according to weight;

[0026] (b) mixing the raw materials, heating them, and dispersing them at high speed to obtain a mixed solution;

[0027] (c) filtering and sterilizing the mixed solution to obtain the γ-aminobutyric acid beverage for improving sleep.

[0028] Preferably, the heating temperature is 50-60°C.

[0029] Preferably, the filter mesh number used for the filtration is 100-150 meshes.

[0030] Preferably, the sterilization method is high temperature sterilization.

[0031] Preferably, the high temperature sterilization temperature is 110-120° C. and the time is 10-20 min.

[0032] Compared with the prior art, the beneficial effects of the present invention include at least:

[0033] The γ-aminobutyric acid beverage for improving sleep of the present invention can calm sleep, relieve anxiety, relieve physical fatigue and enhance body immunity through the selection of various raw materials, the addition of L-theanine, γ-aminobutyric acid, chamomile extract, passion fruit powder, and collagen peptide, and supplemented with nutrients such as lemon juice, sodium hyaluronate, pectin, and erythritol. The prepared γ-aminobutyric acid beverage for improving sleep has excellent sleep improvement function, good effect and quick effect through the joint action of various raw materials.

[0034] The γ-aminobutyric acid beverage for improving sleep of the present invention has 0 added sucrose, 0 fat and 0 preservatives, and is safe, healthy and effective for consumers to drink. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following is a brief introduction to the drawings required for the specific embodiments or the prior art description. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, the elements or parts are not necessarily drawn according to the actual scale.

[0036] Figure 1 This is a moving trajectory diagram of the zebrafish in the experimental example of the present invention. DETAILED DESCRIPTION

[0037] The following embodiments of the technical solution of the present invention are described in detail in conjunction with the embodiments. The following embodiments are only used to more clearly illustrate the technical solution of the present invention, and are therefore only used as examples, and cannot be used to limit the protection scope of the present invention.

[0038] It should be noted that, unless otherwise specified, the technical terms or scientific terms used in this application should have the common meanings understood by those skilled in the art to which the present invention belongs.

[0039] The embodiment of the present invention provides a γ-aminobutyric acid beverage for improving sleep, and the γ-aminobutyric acid beverage for improving sleep includes the following raw materials in parts by weight:

[0040] 2-6 parts of erythritol, 0.83-2.52 parts of resistant dextrin, 0.4-1 parts of polydextrose, 1.8-2.2 parts of lemon juice, 0.15-0.28 parts of L-theanine, 0.21-0.55 parts of chamomile extract, 0.02-0.06 parts of passionflower powder, 0.15-0.28 parts of gamma-aminobutyric acid, 0.4-1 parts of collagen peptide, 0.03-0.1 parts of sodium hyaluronate, 0.12-0.43 parts of pectin and 45-50 parts of water.

[0041] The γ-aminobutyric acid beverage for improving sleep of the present invention can achieve the effects of calming sleep, relieving anxiety, relieving physical fatigue and enhancing body immunity through the selection of various raw materials, the addition of L-theanine, γ-aminobutyric acid, chamomile extract, passionflower powder and collagen peptide, and the supplementation of nutrients such as lemon juice, sodium hyaluronate, pectin and erythritol. Through the combined action of various raw materials, the prepared γ-aminobutyric acid beverage for improving sleep has excellent sleep improvement function, and the effect is good and the effect is fast.

[0042] In one embodiment, the γ-aminobutyric acid beverage for improving sleep comprises the following raw materials in parts by weight:

[0043] 4 parts of erythritol, 1.2 parts of resistant dextrin, 0.8 parts of polydextrose, 2 parts of lemon juice, 0.2 parts of L-theanine, 0.4 parts of chamomile extract, 0.04 parts of passion fruit powder, 0.2 parts of gamma-aminobutyric acid, 0.8 parts of collagen peptide, 0.06 parts of sodium hyaluronate, 0.3 parts of pectin and 50 parts of water.

[0044] Another embodiment of the present invention provides a method for preparing the above-mentioned γ-aminobutyric acid beverage for improving sleep, the preparation method comprising the following steps:

[0045] (a) weighing each raw material according to weight;

[0046] (b) mixing the raw materials, heating them, and dispersing them at high speed to obtain a mixed solution;

[0047] (c) filtering and sterilizing the mixed solution to obtain the γ-aminobutyric acid beverage for improving sleep.

[0048] In some embodiments, the heating temperature is 50-60°C.

[0049] In some embodiments, the filtration uses a filter with a mesh size of 100 to 150.

[0050] In some embodiments, the sterilization method is high temperature sterilization.

[0051] In some embodiments, the high temperature sterilization temperature is 110-120° C. and the time is 10-20 min.

[0052] The technical solution of the present invention is further described in detail below through specific embodiments.

[0053] Example 1

[0054] This embodiment is a γ-aminobutyric acid beverage for improving sleep, and the γ-aminobutyric acid beverage for improving sleep includes the following raw materials in parts by weight:

[0055] 6 parts of erythritol, 0.83 parts of resistant dextrin, 1 part of polydextrose, 1.8 parts of lemon juice, 0.28 parts of L-theanine, 0.55 parts of chamomile extract, 0.02 parts of passion fruit powder, 0.28 parts of gamma-aminobutyric acid, 1 part of collagen peptide, 0.03 parts of sodium hyaluronate, 0.43 parts of pectin and 50 parts of water.

[0056] The preparation method of the above-mentioned γ-aminobutyric acid beverage for improving sleep comprises the following steps:

[0057] (a) weighing each raw material according to weight;

[0058] (b) mixing the raw materials, heating them to 50° C., and dispersing them at high speed to obtain a mixed solution;

[0059] (c) The mixed solution is filtered through a 150-mesh filter and then sterilized at 120° C. for 10 min to obtain the γ-aminobutyric acid beverage for improving sleep.

[0060] Example 2

[0061] This embodiment is a γ-aminobutyric acid beverage for improving sleep, and the γ-aminobutyric acid beverage for improving sleep includes the following raw materials in parts by weight:

[0062] 2 parts of erythritol, 2.52 parts of resistant dextrin, 0.4 parts of polydextrose, 2.2 parts of lemon juice, 0.15 parts of L-theanine, 0.21 parts of chamomile extract, 0.06 parts of passion fruit powder, 0.15 parts of gamma-aminobutyric acid, 0.4 parts of collagen peptide, 0.1 parts of sodium hyaluronate, 0.12 parts of pectin and 45 parts of water.

[0063] The preparation method of the above-mentioned γ-aminobutyric acid beverage for improving sleep comprises the following steps:

[0064] (a) weighing each raw material according to weight;

[0065] (b) mixing the raw materials, heating them to 60° C., and dispersing them at high speed to obtain a mixed solution;

[0066] (c) The mixed solution is filtered through a 100-mesh filter and then sterilized at 110° C. for 20 min to obtain the γ-aminobutyric acid beverage for improving sleep.

[0067] Example 3

[0068] This embodiment is a γ-aminobutyric acid beverage for improving sleep, and the γ-aminobutyric acid beverage for improving sleep includes the following raw materials in parts by weight:

[0069] 4 parts of erythritol, 1.2 parts of resistant dextrin, 0.8 parts of polydextrose, 2 parts of lemon juice, 0.2 parts of L-theanine, 0.4 parts of chamomile extract, 0.04 parts of passion fruit powder, 0.2 parts of gamma-aminobutyric acid, 0.8 parts of collagen peptide, 0.06 parts of sodium hyaluronate, 0.3 parts of pectin and 50 parts of water.

[0070] The preparation method of the above-mentioned γ-aminobutyric acid beverage for improving sleep comprises the following steps:

[0071] (a) weighing each raw material according to weight;

[0072] (b) mixing the raw materials, heating them to 55° C., and dispersing them at high speed to obtain a mixed solution;

[0073] (c) The mixed solution is filtered through a 120-mesh filter and then sterilized at 120° C. for 15 minutes to obtain the γ-aminobutyric acid beverage for improving sleep.

[0074] Comparative Example 1

[0075] This comparative example is a γ-aminobutyric acid beverage for improving sleep, and the γ-aminobutyric acid beverage for improving sleep includes the following raw materials in parts by weight:

[0076] 4 parts of erythritol, 1.2 parts of resistant dextrin, 0.8 parts of polydextrose, 2 parts of lemon juice, 0.1 parts of L-theanine, 0.33 parts of chamomile extract, 0.01 parts of passion fruit powder, 0.4 parts of gamma-aminobutyric acid, 0.8 parts of collagen peptide, 0.06 parts of sodium hyaluronate, 0.3 parts of pectin and 50 parts of water.

[0077] The preparation method of the above-mentioned γ-aminobutyric acid beverage for improving sleep comprises the following steps:

[0078] (a) weighing each raw material according to weight;

[0079] (b) mixing the raw materials, heating them to 55° C., and dispersing them at high speed to obtain a mixed solution;

[0080] (c) The mixed solution is filtered through a 120-mesh filter and then sterilized at 120° C. for 15 minutes to obtain the γ-aminobutyric acid beverage for improving sleep.

[0081] Experimental example

[0082] This experiment is a zebrafish sleep experiment:

[0083] Experimental principle:

[0084] Zebrafish have a similar nervous system to mammals. Most of the molecules and cell groups (monoaminergic, cholinergic, hypothalaminergic) that play a role in sleep regulation in mammals are conserved in zebrafish. GABA is a naturally occurring non-protein amino acid and an important inhibitory neurotransmitter in the central nervous system of mammals. Pentylenetetrazol (PTZ) is a GABA inhibitor. Low doses of PTZ can induce bipolar disorder with both mania and depression, causing insomnia. Zebrafish with insomnia will show abnormal behavior, which is manifested by a significant increase in total movement distance, which can be observed with a behavioral analyzer. The positive drug is oxazepam.

[0085] Zebrafish behavior trajectory tracking system (DanioVision) (BOM-ZDAN-OBS, Beijing Rhodas Information Technology Co., Ltd.), pentylenetetrazol (CAS: 54-95-5), oxadiazine (CAS: 604-75--1);

[0086] Experimental system: wild AB strain zebrafish; zebrafish age: 5 days after fertilization; experimental sample size per group: 30 per well, 1 well per group.

[0087] The zebrafish were divided into groups, specifically including a normal control group, a model control group, a beverage group of Example 3, a beverage group of Control Example 1, and a positive control group, wherein the normal control group was not treated in any way, and the other groups were all modeled with pentylenetetrazol, and the model control group was the zebrafish after modeling; the beverage group of Example 3 was injected with 5 μL of the beverage of Example 3 into the abdomen of the zebrafish after modeling; the beverage group of Control Example 1 was injected with 5 μL of the beverage of Control Example 1 into the abdomen of the zebrafish after modeling; and the positive control group was injected with 5 μL of 2 mg / ml oxazepam solution into the abdomen of the zebrafish after modeling;

[0088] The movement trajectories of different groups of spotted fish are shown in Figure 2. Figure 1 As shown, Figure 1 In the figure, from top to bottom are the normal control group, the model control group, the beverage group of Example 3, the beverage group of Control Example 1 and the positive control group;

[0089] Figure 1 The average moving distances of the zebrafish in each group are shown in Table 1:

[0090] Table 1

[0091]

[0092]

[0093] Depend on Figure 1 From Table 1, we can see that:

[0094] The γ-aminobutyric acid beverage for improving sleep prepared by the technical solution of the present application has a more excellent effect of improving sleep.

[0095] The first method of GB5009.28-2016 was used to detect the content of sorbic acid and its potassium salt in the γ-aminobutyric acid beverage for improving sleep of Example 3. The test results are shown in Table 2;

[0096] The sucrose content in the γ-aminobutyric acid beverage for improving sleep of Example 3 was detected by the first method of GB5009.8-2016. The detection results are shown in Table 2.

[0097] Table 2

[0098]

[0099] From Table 2, we can see that:

[0100] The γ-aminobutyric acid beverage for improving sleep prepared in the present application does not contain sucrose and potassium sorbate and its potassium salt preservatives.

[0101] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents. These modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present invention, and they should all be included in the scope of the claims and specification of the present invention.

Claims

1. A γ-aminobutyric acid beverage for improving sleep, characterized in that: The γ-aminobutyric acid beverage for improving sleep includes the following raw materials in parts by weight: 2-6 parts of erythritol, 0.83-2.52 parts of resistant dextrin, 0.4-1 parts of polydextrose, 1.8-2.2 parts of lemon juice, 0.15-0.28 parts of L-theanine, 0.21-0.55 parts of chamomile extract, 0.02-0.06 parts of passionflower powder, 0.15-0.28 parts of gamma-aminobutyric acid, 0.4-1 parts of collagen peptide, 0.03-0.1 parts of sodium hyaluronate, 0.12-0.43 parts of pectin and 45-50 parts of water.

2. The γ-aminobutyric acid beverage for improving sleep according to claim 1, characterized in that: The γ-aminobutyric acid beverage for improving sleep includes the following raw materials in parts by weight: 4 parts of erythritol, 1.2 parts of resistant dextrin, 0.8 parts of polydextrose, 2 parts of lemon juice, 0.2 parts of L-theanine, 0.4 parts of chamomile extract, 0.04 parts of passion fruit powder, 0.2 parts of gamma-aminobutyric acid, 0.8 parts of collagen peptide, 0.06 parts of sodium hyaluronate, 0.3 parts of pectin and 50 parts of water.

3. The method for preparing the γ-aminobutyric acid beverage for improving sleep according to claim 1 or 2, characterized in that: The preparation method comprises the following steps: (a) weighing each raw material according to weight; (b) mixing the raw materials, heating them, and dispersing them at high speed to obtain a mixed solution; (c) filtering and sterilizing the mixed solution to obtain the γ-aminobutyric acid beverage for improving sleep.

4. The preparation method according to claim 3, characterized in that: The heating temperature is 50-60°C.

5. The preparation method according to claim 3, characterized in that: The mesh number of the filter used in the filtration is 100 to 150 meshes.

6. The preparation method according to claim 3, characterized in that: The sterilization method is high temperature sterilization.

7. The preparation method according to claim 6, characterized in that: The high temperature sterilization temperature is 110-120° C. and the time is 10-20 minutes.

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