Concentrated Liuwei Dihuang pill and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a concentrated Liuwei Dihuang pill and a preparation method thereof.The concentrated Liuwei Dihuang pill is prepared from, by weight, 80-150 parts of prepared rehmannia roots, 50-80 parts of wine-prepared fructus corni, 40-50 parts of moutan bark, 50-60 parts of Chinese yam, 40-50 parts of poria cocos, 40-50 parts of rhizoma alismatis, 20-30 parts of a nourishing agent, 10-20 parts of a nourishing agent and 5-10 parts of a supplement. On the basis of traditional six-ingredient rehmannia pills, a nourishing agent, a nourishing agent and a supplement are specially added, effective components in the nourishing agent can achieve the effects of nourishing yin and moistening lung, tonifying kidney and securing essence, and tonifying spleen and replenishing qi, are beneficial to male health maintenance, can tonify kidney and protect liver, and strengthen yang and secure essence, and are beneficial to sexual neurasthenia patients with impotence, premature ejaculation, spermatorrhea and the like; meanwhile, the nourishing agent can effectively nourish the body and reduce damage caused by tobacco and wine to the human body, and the oyster essence powder is added and is rich in taurine, glycogen, physiological activators peculiar to marine organisms, amino acids essential to the human body and a large number of microelements beneficial to the human body, so that a good nourishing effect on the human body is achieved.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a concentrated Liuwei Dihuang pill and a preparation method thereof. Background Art

[0002] Liuwei Dihuang Pills is a traditional Chinese medicine prescription developed according to TCM theory, mainly used to nourish yin and tonify the kidney. Nowadays, people are in a sub-healthy state due to stressful life, staying up late, overwork, etc., and show symptoms of kidney yin deficiency. As people age, their body functions gradually decline. Elderly people may have symptoms of kidney yin deficiency, and Liuwei Dihuang Pills can be used for conditioning. However, the current ingredients and efficacy of Liuwei Dihuang Pills are relatively simple, and most of the people who take Liuwei Dihuang Pills are middle-aged men. These people usually have a gradual decline in physical function, often feel tired, physically weak, have low immunity, sexual dysfunction, etc., and may also be accompanied by damage to the body caused by smoking and drinking. Taking traditional Liuwei Dihuang Pills alone cannot achieve good results, and improvements are needed. Summary of the invention

[0003] The object of the present invention is to provide a concentrated Liuwei Dihuang Pill and a preparation method thereof, so as to solve the problems raised in the above-mentioned background technology.

[0004] To achieve the above-mentioned purpose, the present invention provides the following technical scheme: a concentrated Liuwei Dihuang Pill, which comprises the following raw materials by weight: 80-150 parts of Rehmannia root, 50-80 parts of Cornus officinalis wine, 40-50 parts of Paeonia suffruticosa, 50-60 parts of Dioscorea opposita, 40-50 parts of Poria cocos, 40-50 parts of Alisma orientalis, 20-30 parts of tonic, 10-20 parts of nourishing agent, and 5-10 parts of supplement.

[0005] Preferably, the tonic includes maca, sea ginseng, red dates, wolfberry, and mulberry seeds, and the percentage of these components in the tonic is: maca 20-40%, sea ginseng 3-5%, red dates 20-40%, wolfberry 20-40%, mulberry seeds 20-40%. These ingredients have the effects of nourishing yin and moistening the lungs, benefiting the kidneys and consolidating essence, and nourishing the spleen and replenishing qi. They help to improve soreness of the waist and knees, improve sleep quality, replenish energy, and improve kidney deficiency. For sexual dysfunction caused by mild kidney deficiency, drinking it for two months may show improvement. For more serious kidney deficiency, it may take longer to drink it and cooperate with drug treatment. It is also helpful for men to maintain health, can nourish the kidneys and protect the liver, strengthen yang and consolidate essence, and is beneficial for people with sexual neurasthenia such as impotence, premature ejaculation, and spermatorrhea.

[0006] Preferably, the nourishing agent includes a first nourishing agent and a second nourishing agent, and the added nourishing agent is one of the first nourishing agent and the second nourishing agent or a mixture of the first nourishing agent and the second nourishing agent.

[0007] Preferably, the components and their percentages in the first nourishing agent are: Platycodon 30-40%, lily 30-40%, and Momordica grosvenori 30-40%. Platycodon is an expectorant, which has the effects of invigorating the lung qi, removing phlegm and discharging pus, and is suitable for symptoms such as cough, excessive sputum, sore throat, and hoarseness. Lily has the effects of moistening the lungs and relieving cough, clearing the heart and calming the nerves, and is suitable for cough and hemoptysis caused by lung heat, as well as dry cough and no sputum caused by insufficient fluid in the lungs and dry cough. Momordica grosvenori is called the lung fruit, and is a strong one that clears, moistens, and nourishes the lungs, and helps to strengthen the spleen and stomach, increase appetite, and nourish qi and blood.

[0008] Preferably, the components and their percentages in the second nourishing agent are: 30-40% Pueraria root, 30-40% Schisandra chinensis, and 30-40% Coptis chinensis. Pueraria root has a certain protective effect on alcohol-induced liver damage, and can reduce the activity of fatty acid synthase in the liver and reduce the deposition of fat in the liver. Pueraria root has a regulatory effect on nervous system dysfunction caused by long-term excessive drinking, and can promote the metabolism and repair of the central nervous system. Coptis chinensis is suitable for gastrointestinal discomfort caused by long-term drinking, such as stomach burning pain, nausea and vomiting, etc., but it should be noted that Coptis chinensis is bitter and cold, and should not be used by people with weak spleen and stomach.

[0009] Preferably, the supplement is oyster powder, which is a marine biological product extracted and refined using oyster meat as the main raw material using special equipment. It is rich in taurine, glycogen and physiologically active substances unique to marine organisms, essential amino acids for the human body, and rich and appropriate proportions of zinc, iron, copper, iodine, selenium and other trace elements beneficial to the human body. It can nourish and strengthen the body, moisten the lungs and kidneys, calm the mind, improve intelligence and brain health, benefit the stomach and produce fluid, strengthen tendons and bones, and refine the skin and beautify the face.

[0010] A method for preparing concentrated Liuwei Dihuang Pills comprises the following steps:

[0011] S1: Pretreatment of medicinal materials: wash the medicinal materials to be processed, remove impurities, and dry the washed medicinal materials. Drying equipment is usually used to control the temperature between 60-80°C until the moisture content of the medicinal materials drops below 5%;

[0012] S2: Grinding the medicinal materials, first coarsely grinding the dried medicinal materials to facilitate extraction, and then finely grinding the coarsely ground medicinal materials, passing through an 80-mesh sieve to obtain fine powder;

[0013] S3: Concentrated extraction, first decocting the fine powder obtained in the previous step, mixing the fine powder according to the content component ratio, adding 8-10 times the amount of water, decocting, usually decocting 2-3 times, each time for 1-2 hours, after the decoction is completed, filtering the medicinal liquid, collecting the filtrate, putting the filtrate into a concentration tank, heating and concentrating under reduced pressure conditions, and controlling the temperature at 60-80°C until it is concentrated to 1 / 4-1 / 5 of the original volume to obtain a concentrated medicinal liquid. During the decoction process, attention should be paid to controlling the heat and time to avoid the destruction of the effective ingredients;

[0014] S4: making pills. Before making pills, a small amount of auxiliary materials may be added to improve the taste, or not. The concentrated liquid medicine is mixed with an appropriate amount of auxiliary materials (such as honey, rice flour, etc.), and the proportion of honey is usually 10-20% of the liquid medicine. Then, a pill making machine or a manual method is used to make the mixture into small pills with a diameter of about 3-5 mm, and then the prepared pills are placed in a drying chamber;

[0015] S5: Packaging. The dried balls need to undergo quality inspection, including weight difference, content determination, microbial limit, etc. Balls that pass the inspection are packaged, usually in small bags, each bag containing a certain number of balls.

[0016] Preferably, during the concentrated extraction, stirring should be continued to prevent the liquid medicine from burning.

[0017] Preferably, the diameter and weight of the pills prepared in S4 should be uniform to ensure that the dosage of the medicine is accurate each time.

[0018] Preferably, the temperature of the drying chamber in S4 should not be too high to avoid damaging the efficacy of the medicine. The temperature is controlled at 40-60° C. and the drying is performed until the moisture content is less than 9%.

[0019] Compared with the prior art, the present invention has the following beneficial effects:

[0020] The invention provides a concentrated Liuwei Dihuang Pill and a preparation method thereof. On the basis of the traditional Liuwei Dihuang Pill, a nourishing agent, a nourishing agent and a supplement are specially added. The effective ingredients in the nourishing agent can nourish yin and moisten the lungs, invigorate the kidneys and consolidate the essence, invigorate the spleen and invigorate qi, are helpful for male health preservation, can invigorate the kidneys and protect the liver, strengthen yang and consolidate the essence, and are beneficial to those with sexual neurasthenia such as impotence, premature ejaculation, and spermatorrhea. At the same time, the nourishing agent can effectively nourish the body and reduce the damage caused by tobacco and alcohol to the human body. The addition of oyster essence powder is rich in taurine, glycogen and physiologically active substances unique to marine organisms, essential amino acids for the human body and a large number of trace elements beneficial to the human body, and has a good nourishing effect on the human body. DETAILED DESCRIPTION

[0021] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0022] The invention provides a technical solution: a concentrated Liuwei Dihuang Pill, which comprises the following raw materials by weight: 80-150 parts of cooked rehmannia root, 50-80 parts of wine-boiled cornus fruit, 40-50 parts of peony bark, 50-60 parts of yam, 40-50 parts of poria, 40-50 parts of oriental rhizome, 20-30 parts of tonic, 10-20 parts of nourishing agent and 5-10 parts of supplement.

[0023] The tonic includes maca, sea ginseng, red dates, wolfberry, and mulberry seeds. The percentage of these components in the tonic is: maca 20-40%, sea ginseng 3-5%, red dates 20-40%, wolfberry 20-40%, mulberry seeds 20-40%. These ingredients have the effects of nourishing yin and moistening the lungs, benefiting the kidneys and consolidating essence, nourishing the spleen and replenishing qi, which can help improve soreness of the waist and knees, improve sleep quality, replenish energy, and improve kidney deficiency. For sexual dysfunction caused by mild kidney deficiency, there may be improvement if you drink it for two months. For more serious kidney deficiency, you may need to drink it for a longer time and cooperate with drug treatment. It also helps men to maintain health, can nourish the kidneys and protect the liver, strengthen yang and consolidate essence. It is beneficial for people with sexual neurasthenia such as impotence, premature ejaculation, and spermatorrhea.

[0024] The nourishing agent includes a first nourishing agent and a second nourishing agent, and the added nourishing agent is one of the first nourishing agent and the second nourishing agent or a mixture of the first nourishing agent and the second nourishing agent. The components and their percentages in the first nourishing agent are: 30-40% of Platycodon grandiflorum, 30-40% of Lilium bupleuri, and 30-40% of Momordica grosvenori. Platycodon grandiflorum is an expectorant, which has the effects of opening up the lung qi, removing phlegm and discharging pus, and is suitable for symptoms such as cough, phlegm, sore throat, and hoarseness. Lilium bupleuri has the effects of moistening the lungs and relieving cough, clearing the heart and calming the mind, and is suitable for cough and hemoptysis caused by lung heat, as well as symptoms such as dry cough and no phlegm caused by insufficient body fluid in the lungs and dry cough. Momordica grosvenori is called a lung fruit, which is a strong one for clearing, moistening, and nourishing the lungs, and helps to strengthen the spleen and stomach, increase appetite, and nourish qi and blood. The first nourishing agent can effectively nourish the lungs and reduce the damage caused by smoking to the human body. The components and their percentages in the second nourishing agent are: 30-40% Pueraria root, 30-40% Schisandra chinensis, and 30-40% Coptis chinensis. Pueraria root has a certain protective effect on alcohol-induced liver damage, and can reduce the activity of fatty acid synthase in the liver and reduce the deposition of fat in the liver. Pueraria root has a regulating effect on nervous system dysfunction caused by long-term excessive drinking, and can promote the metabolism and repair of the central nervous system. Coptis chinensis is suitable for gastrointestinal discomfort caused by long-term drinking, such as burning stomach, nausea and vomiting, etc., but it should be noted that Coptis chinensis is bitter and cold, and it is not suitable for people with spleen and stomach deficiency. The second nourishing agent can effectively alleviate the damage caused by long-term drinking to the human body and play a nourishing effect.

[0025] The supplement is oyster powder. Oyster powder is made from oyster meat as the main raw material and is extracted and refined using special equipment. It is a marine biological product that is rich in taurine, glycogen and physiologically active substances unique to marine organisms, essential amino acids for the human body, and rich and appropriate proportions of zinc, iron, copper, iodine, selenium and other trace elements that are beneficial to the human body. It can nourish and strengthen the body, moisten the lungs and kidneys, calm the mind, improve intelligence and brain health, benefit the stomach and produce fluid, strengthen the tendons and bones, and refine the skin and beautify the face.

[0026] On the basis of traditional Liuwei Dihuang Pills, tonics, nourishing agents and supplements are specially added. The effective ingredients in the tonics can nourish yin and moisten the lungs, benefit the kidneys and consolidate essence, nourish the spleen and replenish qi, which is helpful for men's health, can nourish the kidneys and protect the liver, strengthen yang and consolidate essence, and is beneficial for those with sexual neurasthenia such as impotence, premature ejaculation, and spermatorrhea. At the same time, the nourishing agents can effectively nourish the body and reduce the damage caused by tobacco and alcohol to the human body. The addition of oyster essence powder, which is rich in taurine, glycogen and physiologically active substances unique to marine organisms, essential amino acids for the human body and a large number of trace elements beneficial to the human body, has a good nourishing effect on the human body.

[0027] A method for preparing concentrated Liuwei Dihuang Pills comprises the following steps:

[0028] S1: Pretreatment of medicinal materials: wash the medicinal materials to be processed, remove impurities, and dry the washed medicinal materials. Drying equipment is usually used to control the temperature between 60-80°C until the moisture content of the medicinal materials drops below 5%;

[0029] S2: Grinding the medicinal materials, first coarsely grinding the dried medicinal materials to facilitate extraction, and then finely grinding the coarsely ground medicinal materials, passing through an 80-mesh sieve to obtain fine powder;

[0030] S3: Concentrated extraction, firstly, the fine powder obtained in the previous step is decocted, and during the concentrated extraction, it should be stirred continuously to prevent the medicinal liquid from burning. The fine powder is mixed according to the content component ratio, and 8-10 times the amount of water is added for decocting. Usually, the decocting is performed 2-3 times, each time for 1-2 hours. After the decocting is completed, the medicinal liquid is filtered, and the filtrate is collected. The filtrate is placed in a concentration tank, and heated and concentrated under reduced pressure conditions, and the temperature is controlled at 60-80°C until it is concentrated to 1 / 4-1 / 5 of the original volume to obtain a concentrated medicinal liquid. During the decocting process, attention should be paid to controlling the heat and time to avoid the destruction of the effective ingredients;

[0031] S4: pill making. Before pill making, a small amount of auxiliary materials can be added to improve the taste, or not. The concentrated liquid medicine is mixed with an appropriate amount of auxiliary materials (such as honey, rice flour, etc.). The proportion of honey is usually 10-20% of the liquid medicine. Then, a pill making machine or manual method is used. The diameter and weight of the pills in S4 should be uniform to ensure the accurate dosage of each dose. The mixture is made into small pills with a diameter of about 3-5 mm. Then, the prepared pills are placed in a drying room. The temperature in the drying room should not be too high to avoid destroying the efficacy of the medicine. The temperature is controlled at 40-60°C and dried until the moisture content is less than 9%;

[0032] S5: Packaging. The dried balls need to undergo quality inspection, including weight difference, content determination, microbial limit, etc. Balls that pass the inspection are packaged, usually in small bags, each bag containing a certain number of balls.

[0033] Specific embodiment 1: A concentrated Liuwei Dihuang Pill, which includes the following weight components: 80 parts of Rehmannia glutinosa, 55 parts of cornus officinalis, 40 parts of peony bark, 60 parts of yam, 45 parts of Poria cocos, 45 parts of Alisma orientalis, 20 parts of tonic, 10 parts of nourishing agent, and 6 parts of supplement. The percentage of components in the nourishing agent is: 25% of maca, 5% of sea ginseng, 25% of red dates, 25% of wolfberry, and 20% of mulberry. The components and their percentages in the first nourishing agent are: 35% of Platycodon grandiflorum, 35% of lily, and 30% of monk fruit. The components and their percentages in the second nourishing agent are: 35% of Pueraria root, 35% of Schisandra chinensis, and 30% of Coptis chinensis.

[0034] Specific embodiment 2: A concentrated Liuwei Dihuang Pill, which includes the following weight components: 100 parts of Rehmannia glutinosa, 60 parts of cornus officinalis, 60 parts of peony bark, 55 parts of yam, 40 parts of Poria cocos, 40 parts of Alisma orientalis, 25 parts of tonic, 15 parts of nourishing agent, and 8 parts of supplement. The percentage of components in the tonic is: 20% maca, 3% sea ginseng, 30% red dates, 25% wolfberry, and 22% mulberry. The components and their percentages in the first nourishing agent are: 30% platycodon, 30% lily, and 40% monk fruit. The components and their percentages in the second nourishing agent are: 40% kudzu root, 30% schisandra chinensis, and 30% coptis root.

[0035] Specific embodiment 3: A concentrated Liuwei Dihuang Pill, which includes the following weight components: 120 parts of Rehmannia glutinosa, 65 parts of cornus officinalis, 45 parts of peony bark, 50 parts of yam, 50 parts of Poria cocos, 50 parts of Alisma orientalis, 25 parts of tonic, 20 parts of nourishing agent, and 10 parts of supplement. The percentage of components in the tonic is: 28% of maca, 4% of sea ginseng, 22% of red dates, 23% of wolfberry, and 23% of mulberry. The components and their percentages in the first nourishing agent are: 35% of Platycodon grandiflorum, 30% of lily, and 35% of monk fruit. The components and their percentages in the second nourishing agent are: 30% of Pueraria root, 35% of Schisandra chinensis, and 35% of Coptis chinensis.

[0036] Specific embodiment 4: A concentrated Liuwei Dihuang Pill, which includes the following weight components: 140 parts of Rehmannia glutinosa, 60 parts of cornus officinalis, 50 parts of peony bark, 50 parts of yam, 40 parts of Poria cocos, 45 parts of Alisma orientalis, 30 parts of tonic, 20 parts of nourishing agent, and 8 parts of supplement. The percentage of components in the tonic is: 28% of maca, 4% of sea ginseng, 22% of red dates, 25% of wolfberry, and 25% of mulberry. The components and their percentages in the first nourishing agent are: 30% of Platycodon grandiflorum, 30% of lily, and 40% of monk fruit. The components and their percentages in the second nourishing agent are: 32% of Pueraria root, 38% of Schisandra chinensis, and 30% of Coptis chinensis.

[0037] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A concentrated Liuwei Dihuang Pill, characterized by: The concentrated Liuwei Dihuang Pill comprises the following raw materials by weight: 80-150 parts of cooked rehmannia root, 50-80 parts of cornus officinalis, 40-50 parts of peony bark, 50-60 parts of yam, 40-50 parts of tuckahoe, 40-50 parts of oriental rhizome, 20-30 parts of tonic, 10-20 parts of nourishing agent and 5-10 parts of supplement.

2. The concentrated Liuwei Dihuang Pill according to claim 1, characterized in that: The tonic includes maca, sea ginseng, red dates, wolfberry, and mulberry seeds, and the percentages of these components in the tonic are: maca 20-40%, sea ginseng 3-5%, red dates 20-40%, wolfberry 20-40%, and mulberry seeds 20-40%.

3. The concentrated Liuwei Dihuang Pill according to claim 1, characterized in that: The nourishing agent includes a first nourishing agent and a second nourishing agent, and the added nourishing agent is one of the first nourishing agent and the second nourishing agent or a mixture of the first nourishing agent and the second nourishing agent.

4. The concentrated Liuwei Dihuang Pill according to claim 3, characterized in that: The components and their percentages in the first nourishing agent are: 30-40% Platycodon grandiflorum, 30-40% Lilium serrata, and 30-40% Momordica grosvenori.

5. The concentrated Liuwei Dihuang Pill according to claim 4, characterized in that: The components and their percentages in the second nourishing agent are: 30-40% of Pueraria root, 30-40% of Schisandra chinensis, and 30-40% of Coptis chinensis.

6. The concentrated Liuwei Dihuang Pill according to claim 1, characterized in that: The supplement is oyster extract powder.

7. A method for preparing the concentrated Liuwei Dihuang Pills according to any one of claims 1 to 6, characterized in that: The following steps are included: S1: Pretreatment of medicinal materials: wash the medicinal materials to be processed, remove impurities, and dry the washed medicinal materials, usually using drying equipment, until the moisture content of the medicinal materials drops below 5%; S2: Grinding the medicinal materials, first coarsely grinding the dried medicinal materials to facilitate extraction, and then finely grinding the coarsely ground medicinal materials, passing through an 80-mesh sieve to obtain fine powder; S3: Concentration extraction, first decocting the fine powder obtained in the previous step, mixing the fine powder according to the content component ratio, adding 8-10 times the amount of water, decocting, after the decoction is completed, filtering the medicinal liquid, collecting the filtrate, placing the filtrate in a concentration tank, and heating and concentrating under reduced pressure conditions; S4: pelleting The mixture is formed into small pellets with a diameter of about 3-5 mm using a pelleting machine or by manual method, and the prepared pellets are then placed in a drying chamber; S5: Packaging. The dried balls need to undergo quality inspection, including weight difference, content determination, microbial limit, etc. Balls that pass the inspection are packaged, usually in small bags, each bag containing a certain number of balls.

8. A method for preparing concentrated Liuwei Dihuang Pills according to claim 7, characterized in that: During concentrated extraction, the solution should be stirred constantly to prevent it from burning.

9. A method for preparing concentrated Liuwei Dihuang Pills according to claim 7, characterized in that: The diameter and weight of the pills prepared in S4 should be uniform to ensure that the dosage is accurate each time.

10. A method for preparing concentrated Liuwei Dihuang Pills according to claim 7, characterized in that: The temperature of the drying chamber in S4 should not be too high to avoid damaging the efficacy of the medicine. The temperature is controlled at 40-60° C. and the drying is performed until the moisture content is less than 9%.