Functional medicine residue feed for preventing proventriculitis of poultry and preparation method of functional medicine residue feed
By combining traditional Chinese medicine residue with conventional feed raw materials and fermentation agents, functional drug residue feed is prepared, which solves the problems of preventing poultry gland gastritis and using traditional Chinese medicine residue resources, and achieves the effect of improving poultry health level and reducing environmental pollution.
Patent Information
- Application Number
- CN202510006818.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-03
- Publication Date
- 2025-05-23
AI Technical Summary
Poultry gland gastritis affects poultry health and economic benefits of the breeding industry. The existing prevention methods rely on antibiotics, resulting in drug resistance problems and drug residues, and the resources of traditional Chinese medicine residues have not been effectively utilized.
By combining traditional Chinese medicine residue, conventional feed raw materials and fermentation agents, a functional medicine residue is prepared. The traditional Chinese medicine residue includes wild horse chasing, platycodon, Pinellia ternata, licorice, and conventional feed raw materials include corn, fish meal, bran, etc., and the fermentation agent includes cellulase, Lactobacillus acidophilus or Lactobacillus casei.
This feed can effectively prevent poultry gland gastritis, improve poultry immunity and health level, reduce environmental pollution, and achieve high-value utilization of traditional Chinese medicine residues and reduce the use of antibiotics.
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Abstract
Description
Technical Field
[0001] The invention relates to a functional medicinal residue feed for preventing poultry glandular gastritis and a preparation method thereof, belonging to the technical field of poultry feed. Background Art
[0002] With the rapid development of poultry farming, poultry proventriculitis has become one of the important diseases that affect the health of poultry and the economic benefits of the farming industry. Poultry proventriculitis mainly affects the digestive system of poultry, leading to indigestion, growth retardation, reduced feed conversion rate, and even death in severe cases. At present, the prevention and treatment of poultry proventriculitis mainly rely on antibiotics and chemical drugs, but the long-term and large-scale use of these drugs may lead to drug resistance and drug residues, posing a threat to food safety and public health.
[0003] At the same time, the rapid development of the traditional Chinese medicine industry has led to the generation of a large amount of traditional Chinese medicine residues. These residues contain incompletely extracted medicinal ingredients and rich nutrients, such as organic matter, sugars, crude protein, etc., and have high resource utilization value. However, the current treatment methods for traditional Chinese medicine residues are mostly stacking, landfilling or incineration, which not only waste resources, but also may pollute the environment.
[0004] Relevant technicians have been looking for a method that can effectively prevent poultry glandular gastritis and realize the resource utilization of traditional Chinese medicine residues. The ideal solution should be able to reduce dependence on antibiotics, reduce the risk of drug residues, while improving the nutritional value of feed and animal immunity and reducing environmental pollution.
[0005] In this context, the present invention aims to provide a functional feed prepared using traditional Chinese medicine residues and a preparation method thereof, which can effectively prevent poultry glandular gastritis, improve the health level and production performance of poultry, and at the same time achieve high-value utilization of traditional Chinese medicine residues and reduce environmental pollution, and has important social, economic and ecological significance. Summary of the invention
[0006] Purpose of the invention: The first purpose of the present invention is to provide a functional medicinal residue feed for preventing glandular gastritis in poultry. The second purpose of the present invention is to provide a method for preparing the functional medicinal residue feed for preventing glandular gastritis in poultry.
[0007] Technical solution: The functional medicinal residue feed for preventing glandular gastritis in poultry described in the present invention is made of the following materials: Chinese medicinal residue, conventional feed raw materials and fermentation agent, wherein the weight ratio of Chinese medicinal residue to conventional feed raw materials is 100:(50-100), the weight of the fermentation agent is 0.1-1.0% of the total weight of the Chinese medicinal residue and conventional feed raw materials, the Chinese medicinal residue includes wild horsetail, platycodon, pinellia, and liquorice; the conventional feed raw materials include corn, fish meal, bran, stone powder, bone meal, salt, baking soda, and straw.
[0008] Furthermore, the fermentation agent includes one or more of cellulase, Lactobacillus acidophilus or Lactobacillus casei.
[0009] Furthermore, the Chinese medicinal residues include 300-500 parts of Herba Cynomorii, 200-300 parts of Platycodon grandiflorum, 150-250 parts of Pinellia ternata, and 100-200 parts of Licorice.
[0010] Furthermore, conventional feed raw materials include 300-400 parts of corn, 20-25 parts of fish meal, 50-100 parts of bran, 10-15 parts of stone powder, 10-15 parts of bone meal, 8-12 parts of salt, 10-15 parts of baking soda, and 50-90 parts of straw.
[0011] The method for preparing the functional medicinal residue feed for preventing proventriculus of poultry according to the present invention comprises the following steps:
[0012] (1) Pretreatment of drug residues: drying and crushing the drug residues;
[0013] (2) Mixed fermentation: Mix the pretreated Chinese medicine residues with conventional feed raw materials and add a fermentation agent for fermentation;
[0014] (3) Drying and packaging: After fermentation is completed, the fermented materials can be dried.
[0015] Furthermore, in step (1), the drying temperature is 55-65° C., and the drying is performed until the moisture content is below 10%.
[0016] Furthermore, in step (1), the particles are crushed to a diameter of less than 1 mm.
[0017] Furthermore, in step (2), the fermentation temperature is 35 to 40° C., and the fermentation time is 24 to 72 hours;
[0018] Further, in step (2), when the fermentation agent is Lactobacillus acidophilus, the viable count of Lactobacillus acidophilus is greater than 10 8 CFU / above.
[0019] Further, in step (2), when the fermentation agent is Lactobacillus casei, the viable count of Lactobacillus casei is 10 9 CFU / g and above.
[0020] Furthermore, in step (2), when the fermentation agent is cellulase, the activity of the cellulase is above 1000 U / g.
[0021] Furthermore, in step (3), the drying temperature is 55-65° C., and the drying is performed until the moisture content is below 12%.
[0022] The present invention utilizes the effective ingredients in the Chinese medicine residues and combines modern feed processing technology to develop a new type of feed that can not only improve the immunity of poultry and prevent proventriculus gastritis, but also realize the resource utilization of Chinese medicine residues, thereby reducing environmental pollution and providing a green, environmentally friendly and efficient feed solution for the animal breeding industry, which is helpful to improve the health level and production efficiency of poultry.
[0023] Beneficial effects: Compared with the prior art, the present invention has the following significant advantages:
[0024] (1) Prevention of proventriculus gastritis: The functional medicinal residue feed of the present invention enhances the immunity of poultry and prevents the occurrence of proventriculus gastritis through the effective ingredients in the traditional Chinese medicine residue.
[0025] (2) Improving the nutritional value of feed: The action of microorganisms during the fermentation process of the method of the present invention improves the nutritional value and digestibility of feed.
[0026] (3) Resource utilization: The present invention realizes the resource utilization of traditional Chinese medicine residues and reduces environmental pollution.
[0027] (4) Reduced use of antibiotics: The present invention reduces the use of antibiotics in poultry feed, reduces drug resistance problems and drug residues. DETAILED DESCRIPTION
[0028] The technical solution of the present invention is further described below in conjunction with embodiments.
[0029] Cellulase: CAS 9012-54-8 (C1184), purchased from Sigma.
[0030] Lactobacillus casei (ATCC 393) was purchased from China Microbiological Strain Query Network.
[0031] Lactobacillus acidophilus (ATCC 4356) was purchased from China Microbiological Strain Query Network.
[0032] Example 1
[0033] (1) Pretreatment of drug residues: Chinese herbal drug residues were collected according to the following weights, including 450 parts of Ye Ma Zhui, 250 parts of Platycodon grandiflorum, 200 parts of Pinellia ternata, and 150 parts of Licorice. The drug residues were dried at 60° C. until the moisture content was less than 10%, and then crushed using a crusher until the particle diameter was less than 1 mm.
[0034] (2) Mixed fermentation: prepare conventional feed raw materials according to the following weights: 350 parts of corn, 22 parts of fish meal, 75 parts of bran, 12 parts of stone powder, 12 parts of bone meal, 10 parts of salt, 12 parts of baking soda, and 70 parts of straw.
[0035] (3) The pretreated Chinese medicine residues were mixed evenly with conventional feed raw materials, and cellulase (activity of 1200 U / g, added in an amount of 0.5% of the total weight of the mixture of Chinese medicine residues and conventional feed raw materials) and Lactobacillus acidophilus (viable count of 10 8 CFU / g, the added amount is 0.3% of the total weight of the mixture of traditional Chinese medicine residues and conventional feed raw materials). The mixture is fermented at 37°C for 48 hours.
[0036] (4) Drying and packaging: After fermentation, the fermented material is dried at 60°C until the moisture content is less than 12%, and then packaged and stored.
[0037] Example 2
[0038] (1) Pretreatment of drug residues: Chinese herbal drug residues were collected according to the following weights, including 350 parts of Ye Ma Zhui, 300 parts of Platycodon grandiflorum, 200 parts of Pinellia ternata, and 100 parts of Licorice. The drug residues were dried at 60° C. until the moisture content was less than 10%, and then crushed to a particle diameter of less than 1 mm.
[0039] (2) Mixed fermentation: prepare conventional feed raw materials according to the following weights: 400 parts of corn, 20 parts of fish meal, 100 parts of bran, 10 parts of stone powder, 15 parts of bone meal, 9 parts of salt, 15 parts of baking soda, and 80 parts of straw.
[0040] (3) The pretreated Chinese medicine residues were mixed with conventional feed raw materials, and cellulase (activity of 1000 U / g, added in an amount of 0.8% of the total weight of the mixture of Chinese medicine residues and conventional feed raw materials) and Lactobacillus casei (viable count of 10 9 CFU / g, the added amount is 0.5% of the total weight of the mixture of Chinese medicine residues and conventional feed raw materials). The mixture was fermented at 37°C for 72 hours.
[0041] (4) Drying and packaging: After fermentation, the fermented material is dried at 60°C until the moisture content is less than 12%, and then packaged and stored.
[0042] Example 3
[0043] (1) Pretreatment of drug residues: Chinese herbal drug residues were collected according to the following weights, including 450 parts of Ye Ma Zhui, 250 parts of Platycodon grandiflorum, 180 parts of Pinellia ternata, and 200 parts of Licorice. The drug residues were dried at 60° C. to a moisture content of less than 10%, and then crushed to a particle diameter of less than 1 mm.
[0044] (2) Mixed fermentation: prepare conventional feed raw materials according to the following weights: 325 parts of corn, 23 parts of fish meal, 85 parts of bran, 13 parts of stone powder, 12 parts of bone meal, 11 parts of salt, 10 parts of baking soda, and 65 parts of straw.
[0045] (3) The pretreated Chinese medicine residues were mixed with conventional feed raw materials, and cellulase (activity of 1100 U / g, added in an amount of 0.6% of the total weight of the mixture of Chinese medicine residues and conventional feed raw materials) and a mixed bacterial agent of Lactobacillus acidophilus and Lactobacillus casei (the number of viable Lactobacillus acidophilus was 10 8 CFU / g, the number of viable Lactobacillus casei is 10 9 CFU / g, the addition amount was 0.4% and 0.4% of the total weight of the mixture of traditional Chinese medicine residue and conventional feed raw materials respectively). The mixture was fermented at 37°C for 48 hours.
[0046] (4) Drying and packaging: After fermentation, the fermented material is dried at 60°C until the moisture content is less than 12%, and then packaged and stored.
[0047] Example 4
[0048] The preparation process is the same as that in Example 3, except that the weight ratio of the Chinese medicinal residue to the conventional feed raw materials is 100:100, the weight of the fermentation agent is 0.1% of the total weight of the Chinese medicinal residue and the conventional feed raw materials, and the rest is the same as in Example 3 to obtain a functional medicinal residue feed.
[0049] Example 5
[0050] The preparation process is the same as that in Example 3, except that the weight ratio of the Chinese medicinal residue to the conventional feed raw materials is 100:200, the weight of the fermentation agent is 0.05% of the total weight of the Chinese medicinal residue and the conventional feed raw materials, and the rest is the same as in Example 3 to obtain a functional medicinal residue feed.
[0051] Comparative Example 1
[0052] The preparation process is the same as that in Example 3, except that the Chinese medicinal residue does not contain Herba Cibotii. The rest is the same as in Example 3, and a functional medicinal residue feed is obtained.
[0053] Example 6
[0054] The dominant bacteria were isolated from the glandular stomach of the sick chicken, stored at 4°C, and identified as Escherichia coli. The Escherichia coli was inoculated into the nutrient broth medium and cultured in a 37°C constant temperature incubator for 12-16 hours to allow the Escherichia coli to recover and grow. The Escherichia coli suspension was diluted with sterile saline to a certain concentration (e.g., 10 6 -10 8CFU / mL), and take 1mL of bacterial suspension in a sterile test tube for later use. The functional medicinal residue feed prepared in Examples 1-5 and Comparative Example 1 was crushed and passed through a 60-mesh sieve; 1g of feed sample was accurately weighed and prepared into a 10% feed suspension with sterile saline. 1mL of Escherichia coli suspension was mixed with 1mL of feed suspension and shaken well as the experimental group; 1mL of Escherichia coli suspension was mixed with 1mL of sterile saline and shaken well as the control group; the mixed suspension was evenly spread on the surface of the agar culture medium; cultured in a constant temperature incubator at 37°C for 24 hours, and the antibacterial rate was calculated. The results are shown in Table 1.
[0055] Example 7
[0056] Embodiment 30-40 day old glandular gastritis chickens were used, and after 5 days of feeding, they were randomly divided into blank control group (compound feed for laying hens during brooding period, Zhengda feed), experimental group 1 (medicine residue feed in embodiment 1), experimental group 2 (medicine residue feed in embodiment 2), experimental group 3 (medicine residue feed in embodiment 3), experimental group 4 (medicine residue feed in embodiment 4), experimental group 5 (medicine residue feed in embodiment 5) and comparison group (medicine residue feed in comparative example 1). They were fed freely for 7 consecutive days, and the feed intake and feces and other related indicators were observed. The results are shown in Table 1.
[0057] Table 1 Component contents of functional medicinal residue feed prepared in Examples 1-5 and Comparative Example 1
[0058]
[0059]
[0060] According to the results in Table 1 above, compared with the functional dregs feed prepared in Comparative Example 1, Examples 1-4 all showed good nutritional ingredients and disease-resistant functional ingredient content, as well as efficient inhibition of pathogens related to proventriculitis, compared with Comparative Example 1. However, in Example 5, when the weight ratio of Chinese medicinal dregs to conventional feed raw materials was 100:200 and the weight of the fermentation agent was 0.05% of the total weight of the Chinese medicinal dregs and conventional feed raw materials, the antibacterial effect on Escherichia coli was not as good as that of Comparative Example 1 without wild horse chase. It can be seen that the amount of Chinese medicinal dregs and conventional feed raw materials and the amount of fermentation agent have a significant restrictive effect on the antibacterial effect of Escherichia coli. These results verify that the functional dregs feed of the present invention (the weight ratio of Chinese medicinal dregs to conventional feed raw materials is 100: (50-100), and the weight of the fermentation agent is 0.1-1.0% of the total weight of the Chinese medicinal dregs and conventional feed raw materials) can effectively prevent poultry proventriculitis and improve the immunity and health level of poultry.
Claims
1. A functional medicinal residue feed for preventing glandular gastritis in poultry, characterized in that: The invention comprises the following materials: Chinese medicinal residues, conventional feed raw materials and fermentation agent, wherein the weight ratio of the Chinese medicinal residues to the conventional feed raw materials is 100:(50-100), the weight of the fermentation agent is 0.1-1.0% of the total weight of the Chinese medicinal residues and the conventional feed raw materials, the Chinese medicinal residues comprise wild horsetail herb, platycodon grandiflorum, pinellia tuber and liquorice; the conventional feed raw materials comprise corn, fish meal, bran, stone powder, bone meal, salt, baking soda and straw.
2. The functional medicinal residue feed for preventing glandular gastritis in poultry according to claim 1, characterized in that: The fermentation agent includes one or more of cellulase, Lactobacillus acidophilus or Lactobacillus casei.
3. The functional medicinal residue feed for preventing proventriculus of poultry according to claim 3, characterized in that: The Chinese medicinal residues include 300-500 parts of Herba Cynomorii, 200-300 parts of Platycodon grandiflorum, 150-250 parts of Pinellia ternata, and 100-200 parts of Licorice.
4. The functional medicinal residue feed for preventing proventriculus of poultry according to claim 3, characterized in that: Conventional feed raw materials include 300-400 parts of corn, 20-25 parts of fish meal, 50-100 parts of bran, 10-15 parts of stone powder, 10-15 parts of bone meal, 8-12 parts of salt, 10-15 parts of baking soda, and 50-90 parts of straw.
5. The method for preparing the functional medicinal residue feed for preventing proventriculus of poultry according to any one of claims 1 to 4, characterized in that: The following steps are involved: (1) Pretreatment of drug residues: drying and crushing the drug residues; (2) Mixed fermentation: Mix the pretreated Chinese medicine residues with conventional feed raw materials and add a fermentation agent for fermentation; (3) Drying and packaging: After fermentation is completed, the fermented materials can be dried.
6. The preparation method according to claim 5, characterized in that: In step (1), the drying temperature is 55-65° C., and the drying is performed until the moisture content is below 10%.
7. The preparation method according to claim 5, characterized in that: In step (1), the particles are crushed to a diameter of less than 1 mm.
8. The preparation method according to claim 6, characterized in that: In step (2), the fermentation temperature is 35 to 40° C. and the fermentation time is 24 to 72 hours.
9. The preparation method according to claim 6, characterized in that: In step (2), when the fermentation agent is Lactobacillus acidophilus, the viable count of Lactobacillus acidophilus is greater than 10 8 CFU / , when the fermentation agent is Lactobacillus casei, the number of viable Lactobacillus casei is 10 9 CFU / g or more, and when the fermentation agent is cellulase, the activity of the cellulase is or more than 1000U / g.
10. The preparation method according to claim 6, characterized in that: In step (3), the drying temperature is 55-65° C., and the drying is performed until the moisture content is below 12%.