Semen ziziphi spinosae composite beverage capable of assisting in improving sleep

Abstract

The invention provides a preparation method of a spina date seed composite beverage for assisting in improving sleep, and belongs to the field of large health food and health food. The solid beverage is prepared from the following components in percentage by weight: 0.2 to 4.5 percent of semen ziziphi spinosae, 3.8 to 10.7 percent of fructus ziziphi spinosae, 1.5 to 11.5 percent of fructus mori, 0.2 to 6.5 percent of radix salviae miltiorrhizae, 0.15 to 5.5 percent of bulbus lilii, 0.3 to 10.3 percent of poria cocos and 1.5 to 9.5 percent of sweetening agents (honey and brown sugar). 0.001 to 0.005 percent of a nutrition enhancer gamma-aminobutyric acid; the beverage is prepared from the following components in percentage by weight: 0.08 to 0.35 percent of organic acid (citric acid, tartaric acid, malic acid and sodium citrate), 0.007 to 0.02 percent of antioxidant (Vc), 0.1 to 0.2 percent of stabilizer, 0.008 to 0.03 percent of table salt and the balance of water. The invention is characterized in that raw materials with homology of medicine and food are used on the premise of not adding hormone, a scientific proportion is obtained through research, a nerve soothing formula for enhancing spina date seeds and mulberries is formed, and meanwhile, the characteristics of quality, flavor, taste, color, fragrance and the like of food are ensured.

Description

Technical Field

[0001] The invention belongs to the field of health foods and health products, and relates to a method for preparing a Chinese date seed composite drink for assisting in improving sleep. Background Art

[0002] Ziziphi Spinosae Semen is a Chinese herbal medicine. It is the seed of the plant Ziziphi Spinosae, which belongs to the Rhamnaceae family. It is mild in nature and sweet in taste. It contains a variety of alkaloids, fatty oils, proteins, flutol, and trace amounts of irritating volatile oils. Functions and indications: nourishing the heart and liver, calming the mind, and astringing sweat and promoting body fluid. It is clinically used to treat insomnia, restlessness, neurasthenia, night sweats, and other symptoms.

[0003] The sour jujube (Ziziphus jujuba var.spinosa (Bunge) Hu ex HF Chow.), the fruit of the jujube tree of the Rhamnaceae family, is reddish brown when ripe and sour in taste, hence the name sour jujube. It is recorded that sour jujube is flat in nature, sweet and sour in taste, and regular consumption can invigorate the spleen and stimulate the appetite, nourish the heart and calm the mind, and restrain sweat. It is mainly used to treat symptoms such as insomnia due to deficiency, excessive sweating due to physical weakness, and thirst due to lack of body fluid.

[0004] Mulberry is the fruit cluster of the mulberry plant of the genus Morus alba L. of the Moraceae family. The ripe fruit clusters are collected and dried in the sun or slightly steamed and then dried in the sun for later use. Mulberry is cold in nature, sweet and sour in taste. Functions and indications: nourishing yin and blood, promoting body fluid and moistening dryness. Indications: symptoms such as liver and kidney yin deficiency, palpitations and insomnia, dry intestines and constipation. Black mulberries are rich in mulberry anthocyanins, which have strong free radical scavenging and antioxidant activities, and have multiple physiological functions such as hypoglycemic, anti-oxidation, anti-allergy, anti-aging, and anti-tumor. They are widely used in food, medicine, cosmetics, and other fields. Mulberry anthocyanins can increase the glucose consumption and uptake of liver cells and the glycogen content, inhibit the expression of gluconeogenesis-related proteins, and promote the expression of glycogen synthesis-related proteins. It is the most important bioactive substance in mulberries, and has multiple physiological activities such as anti-tumor, anti-oxidation, antibacterial, hypoglycemic, hypolipidemic, and immune regulation.

[0005] Salviae miltiorrhizae Radix Et Rhizoma is the root and rhizome of the perennial upright herb of the genus Salvia of the family Lamiaceae. It tastes slightly bitter and slightly cold in nature. It has the effects of promoting blood circulation and removing blood stasis, regulating menstruation and relieving pain, nourishing blood and calming the mind. As a traditional Chinese medicine for promoting blood circulation and removing blood stasis, Salvia miltiorrhiza has the effect of promoting qi and blood circulation, and can promote the circulation of qi and blood by removing blood stasis. It has a good effect in treating depression. It is mainly used in the clinic to treat cardiovascular and cerebrovascular diseases, such as neurasthenia, coronary heart disease, insomnia, depression and palpitations.

[0006] Lily (Lilium brownii var.viridulum Baker), white lily, also known as garlic brain potato, is the dried fleshy scale leaf of Lilium lancifolium Thund.) or Liliumpumilum DC. of the Liliaceae family. The medicinal property is sweet, slightly bitter, and slightly cold. It has the effects of nourishing yin and moistening the lungs, clearing the heart and calming the mind. It is often used to treat yin deficiency with heat, yin deficiency and chronic cough, restlessness caused by virtual heat, insomnia, dreaminess, and trance. Nutritional value: Lily is white in color, tender in flesh, and sweet in taste. It is rich in protein, fat, reducing sugar, calcium, phosphorus, iron, vitamin B, vitamin C and other nutrients, and also contains some special nutrients, such as colchicine and other alkaloids. It has good nutritional and nourishing effects on the human body and is very beneficial for making food. Lily is a plant with medicinal and edible properties, and can be eaten fresh or dried.

[0007] Poria cocos is the dried sclerotium of the fungus Poria cocos (Schw.) Wolf of the Polyporaceae family. It is mild in nature and sweet in taste. It has the effects of promoting diuresis and dispelling dampness, strengthening the spleen and harmonizing the middle, and calming the mind. Because Poria cocos has the effect of calming the mind, it can relieve anxiety and restlessness, regulate the mental state, help people fall asleep better, and improve sleep quality. It is often decocted for consumption, or boiled in water, cooked into porridge or soup, and is also a raw material of medicinal and edible origin.

[0008] The nutritional enhancer γ-aminobutyric acid is a four-carbon non-protein amino acid, referred to as GABA, which is widely present in nature. It can be widely used in food, medical, health care products and other industries. GABA is listed as a new resource food, and its intake is stipulated not to exceed 500mg / d. γ-aminobutyric acid has high physiological activity, participates in a variety of physiological and metabolic activities in the human body, and is also an important substance that inhibits the transmission of human nerve messages. When the human body lacks γ-aminobutyric acid, it will produce symptoms such as anxiety, restlessness, fatigue, and insomnia. Generally, people who are in a high-pressure competitive environment for a long time are prone to lack of γ-aminobutyric acid and need to be supplemented in time to relieve stress.

[0009] Nutritional enhancer Ascorbic acid (Vc) Vitamin C participates in a variety of complex physiological processes in the human body, such as the synthesis of collagen in the body, the formation of antigens, detoxification, and the prevention and treatment of scurvy and other diseases such as local skin inflammation, loss of appetite, dyspnea and general fatigue. It is also effective for symptoms such as ruptured bleeding of capillaries in subcutaneous tissue, bone ends or gums.

[0010] Honey is made by the Chinese honey bees or the Italian honey bees, which are insects of the family Apidae. Traditional Chinese medicine believes that honey is mild in nature, sweet in taste, and can nourish the middle. It is used for diseases such as spleen and stomach weakness, abdominal pain, intestinal moisturizing and laxative, gastritis, and duodenal ulcers.

[0011] Brown sugar is a kind of cane sugar that has not been highly refined and has been formed with honey. It is a red crystal made from the stems of the herbaceous plant sugarcane by squeezing the juice. It is rich in sugar, minerals and glycolic acid. It has the effects of strengthening the spleen and warming the stomach, supplementing nutrition, promoting blood circulation and dispelling cold. 1. Strengthen the spleen and warm the stomach: Brown sugar is warm in nature and sweet in taste. It has the effects of nourishing the middle and replenishing qi, slowing down digestion, strengthening the spleen and warming the stomach. It can be used to treat spleen and stomach deficiency and cold, loss of appetite, indigestion and other symptoms. 2. Nutritional supplement: Brown sugar contains vitamin B, as well as various trace elements such as iron, calcium, sodium, potassium, manganese, and copper. It is rich in nutritional value and can provide the human body with a variety of nutrients needed by the body. 3. Activating blood circulation and dispelling cold: Brown sugar has the effect of activating blood circulation and dispelling cold. Drinking thick brown sugar water before and after menstruation can help menstrual blood to be discharged smoothly, and can relieve discomfort such as menstrual irregularities and lower abdominal distension and pain. Brown sugar contains a lot of iron, which can also replenish the loss of women during menstruation.

[0012] Organic acids participate in many physiological functions in the human body and also have antioxidant effects. In order to maintain the quality of beverages during food processing, they are often used as protective agents, acidulants, absorption regulators, etc. According to the main organic acids naturally present in mulberries and their proportions, the proportions of malic acid, citric acid and tartaric acid in mulberry beverages are appropriately adjusted to make the taste more natural and delicious. Summary of the invention

[0013] The invention aims to provide a method for preparing a Chinese date seed composite beverage for assisting in improving sleep. A method for preparing a Chinese date seed compound beverage for assisting in improving sleep, the technical solution is:

[0014] The invention provides a method for preparing a Chinese jujube seed composite beverage for assisting in improving sleep. The components of the beverage include the following components in percentage by mass: 0.2-4.5% of Chinese jujube seed, 3.8-10.7% of Chinese jujube, 1.5-11.5% of mulberry, 0.2-6.5% of salvia miltiorrhiza, 0.15-5.5% of lily, 0.3-10.3% of poria, 1.5-9.5% of sweetener (honey, brown sugar); 0.001-0.005% of γ-aminobutyric acid as a nutritional enhancer, 0.008-0.03% of salt; 0.08-0.35% of organic acid (citric acid, tartaric acid, malic acid and sodium citrate), 0.007-0.02% of antioxidant (Vc), 0.1-0.2% of stabilizer, and the remainder of purified water.

[0015] A method for preparing a Chinese date seed composite beverage for assisting in improving sleep, the process of which is as follows:

[0016] A method for preparing a Chinese jujube seed compound beverage for assisting in improving sleep, wherein the raw material of the Chinese jujube seed is provided by a supplier of Chinese medicine raw materials;

[0017] A method for preparing a Chinese jujube seed compound beverage for assisting in improving sleep, wherein the raw material, Chinese jujube, is provided by a supplier of Chinese medicine raw materials;

[0018] A method for preparing a Chinese jujube seed compound beverage for assisting in improving sleep, comprising the preparation of raw materials of dried black and white mulberries - the mulberries are dried naturally in the high temperature conditions of the Flaming Mountain in Turpan in summer, and then stored in a cool place after drying.

[0019] A method for preparing a Chinese jujube seed composite drink for assisting in improving sleep comprises mixing components by mass percentage as follows: 0.2-4.5% Chinese jujube seed, 3.8-10.7% Chinese jujube, 1.5-11.5% mulberry, 0.2-6.5% salvia miltiorrhiza, 0.15-5.5% lily and 0.3-10.3% poria, and grinding them into coarse powder as the mixed raw material for the drink.

[0020] A method for preparing a Chinese jujube seed compound beverage for assisting in improving sleep comprises the steps of: mixing raw materials and soaking them in water.

[0021] A method for preparing a Chinese jujube seed compound beverage for assisting in improving sleep, wherein a color protecting agent is added to prevent oxidation of effective ingredients such as anthocyanins.

[0022] The invention discloses a method for preparing a Chinese date seed compound beverage for assisting in improving sleep. The color protecting agents used are vitamin C (0.005%-0.011%) and iodine-free edible salt (0.005%-0.25%).

[0023] A method for preparing a Chinese jujube seed compound beverage for assisting in improving sleep comprises the steps of: soaking mixed raw materials in 60-80°C warm water for 30-120 minutes to prepare a decoction.

[0024] A method for preparing a Chinese jujube seed compound beverage for assisting in improving sleep comprises the following steps: first, boiling, wherein the mass ratio of the boiling material to water is 1:(8-10), boiling for 0.5-1h, and filtering to a specific mesh size of 100-110 meshes.

[0025] A method for preparing a Chinese jujube seed composite beverage for assisting in improving sleep, wherein the second step is decoction, wherein the mass ratio of the cooking material to water is 1:(8-10), the decoction is performed for 0.5-1h, and the specific requirement for filtering is that the filter mesh is filtered to 100-110 meshes.

[0026] A method for preparing a Chinese jujube seed composite beverage for assisting in improving sleep comprises combining a first decoction filtrate and a second decoction filtrate and stirring them evenly.

[0027] A method for preparing a jujube seed compound beverage for assisting in improving sleep, wherein auxiliary materials are added for preparation. The auxiliary materials added are honey, sugar, sweetener, organic acid, and the remaining components are drinking water, which are added to a predetermined scale, ultrafiltered, filled, and sterilized at high temperature and high pressure to obtain a mulberry juice compound beverage.

[0028] A method for preparing a Chinese jujube seed compound beverage for assisting in improving sleep, wherein auxiliary materials added are honey, sugar, sweetener, and organic acid, which are stirred until fully dissolved to form a mixed solution.

[0029] A method for preparing a Chinese jujube seed compound beverage for assisting in improving sleep, comprising concentrating the beverage to a predetermined volume and fixing the volume.

[0030] A method for preparing a Chinese jujube seed compound beverage for assisting in improving sleep, comprising performing ultrafine filtration to obtain an ultrafiltrate.

[0031] A method for preparing a Chinese date seed compound beverage for assisting in improving sleep, comprising homogenizing ultrafine filtered liquid.

[0032] A method for preparing a Chinese date seed compound beverage for assisting in improving sleep, comprising packaging and sealing an ultrafine filtered liquid.

[0033] A method for preparing a Chinese jujube seed compound beverage for assisting in improving sleep, and high temperature and high pressure sterilization. Instruction manual attached:

[0034] Figure 1 The distance that mice move in the open field test (mm / s) Preparation method of a jujube seed compound beverage for assisting in improving sleep, animal experiment and data statistical analysis

[0035] A method for preparing a Chinese date seed compound beverage for assisting in improving sleep, and an animal experiment. (1) Modeling and drug administration Experimental animals: 40 KM mice (Kunming mice) were randomly divided into a blank group, a model group, a mixed formula group and a positive drug group, with 10 mice in each group. They were adaptively fed for 7 days in a laboratory with indoor temperature and natural humidity, 12 / 12h light and dark alternation, free diet and water intake. Among the 40 KM mice, 30 were in the model group and the remaining 10 were in the normal group. The mice in the model group were gavaged with PCPA at a dose of 350 mg / kg every morning for 3 consecutive days. The orbital blood was taken and centrifuged to obtain serum samples. The 5-HT levels in the serum of the mice in the normal control group and the model group were determined. The 5-HT level in the serum of the mice was significantly lower than that of the mice in the normal control group (P<0.01), indicating that the mouse model was successfully established. After modeling, 10 mice in the positive drug group were gavaged with diazepam at a dose of 2.5 mg / kg, and 10 mice in the mixed formula group were gavaged with a compound drink of Ziziphus jujuba seed at a dose of 10 ml / kg·d. The blank group and the model group were gavaged with an equal amount of distilled water. Modeling and drug administration were carried out every morning for 4 consecutive weeks. Observation indicators: (2) Open field experiment mouse movement The mouse was placed in the center of an open box and allowed to adapt for 30 seconds before recording. The mouse's activities in the next unit time were observed. Figure 1 The moving distance of mice in the open field experiment (mm / s) was significantly increased in the model group compared with the blank group (P < 0.05). Compared with the model group, the moving distances of the compound group and the positive control group were shortened, and there were significant statistical differences. There was no statistical significance between the compound group and the positive control group. (3) Sleep latency and sleep duration of mice Compared with the blank group, there was no significant change in the sleep latency of mice in the model group, that is, there was no statistical significance; compared with the model group, the sleep latency of mice in the compound group and the positive control group was shortened, but there was a significant difference in the sleep latency between the model group and the compound group (P < 0.05), while there was no statistical significance between the model group and the positive control group; the sleep time of mice in the compound group and the positive control group was prolonged, and there was a significant difference between the compound group and the model group (P < 0.05), while the sleep time of the positive control group was prolonged compared with the model group, but there was no statistical significance. (Table 1) Comparison of neurotransmitters in hypothalamic tissue of mice in each group ( n=10) (4) Neurotransmitter levels in mouse hypothalamic tissue The neurotransmitter levels in the hypothalamus of mice in each group showed that compared with the blank group, the TPH (tryptophan hydroxylase) concentration in the model group was significantly decreased (P < 0.01), and the TPH concentration in the compound group was significantly increased compared with the model group (P < 0.01). The TPH concentration in the positive control (diazepam) group was increased compared with the model group, but there was no statistical significance ( Figure 1 ); Compared with the blank group, the 5-HT (5-hydroxytryptamine) concentration in the model group was significantly decreased (P<0.01), and compared with the model group, the 5-HT concentration in the compound group and the positive group was significantly increased (P<0.01). Table 2 Comparison of neurotransmitter factors in hypothalamus tissue of mice in each group ( n=10)

[0036] A method for preparing a jujube seed compound beverage for assisting in improving sleep, data statistical analysis, using SPSS26.0 statistical software for statistical analysis. The obtained data are quantitative data, using mean ± standard deviation The mean of multiple samples was tested by One-way ANOVA test, and the pairwise comparison was performed by LSD method. The difference was considered statistically significant when P < 0.05.

Claims

1. A method for preparing a Chinese date seed compound beverage for assisting in improving sleep, characterized in that: The invention comprises the following raw materials in parts by weight: 0.2-4.5% of sour jujube kernel, 3.8-10.7% of sour jujube, 1.5-11.5% of mulberry, 0.2-6.5% of salvia miltiorrhiza, 0.15-5.5% of lily, 0.3-10.3% of poria, 1.5-9.5% of sweetener (honey, brown sugar); 0.001-0.005% of γ-aminobutyric acid as a nutritional enhancer, 0.008-0.03% of salt; 0.08-0.35% of organic acid (citric acid, tartaric acid, malic acid and sodium citrate), 0.007-0.02% of antioxidant (Vc), 0.1-0.2% of stabilizer, and the remaining components are water.

2. The method for preparing a Chinese date seed composite beverage for assisting in improving sleep according to claim 1, characterized in that: The components such as wild jujube seeds, wild jujube, mulberry, salvia miltiorrhiza, lily, poria cocos and honey are all raw materials with medicinal and edible properties.

3. The method for preparing a Chinese date seed composite beverage for assisting in improving sleep according to claim 1, characterized in that: The wild jujube, wild jujube seeds, mulberry, salvia miltiorrhiza, lily and poria are mixed in a certain proportion and then powdered and extracted with pure water.

4. The method for preparing a Chinese date seed composite beverage for assisting in improving sleep according to claim 1, characterized in that: The wild jujube, wild jujube seeds, mulberry, salvia miltiorrhiza, lily and poria are mixed in a certain proportion and then powdered, and the raw material: water ratio is 1:6-10 times and extracted twice.

5. The method for preparing a Chinese date seed composite beverage for assisting in improving sleep according to claim 1, characterized in that: The method comprises extracting the raw material with water at a ratio of 1:6-10 for two times, soaking in pure hot water for 1-2 hours, decocting for 1-2 hours, combining the two water extracts, and concentrating them into a water extract for later use.

6. The method for preparing a Chinese date seed composite beverage for assisting in improving sleep according to claim 1, characterized in that: The sweetener components are honey and brown sugar.

7. The method for preparing a Chinese date seed composite beverage for assisting in improving sleep according to claim 1, characterized in that: The honey is made by the Chinese honey or the Italian honey of the Apidae family.

8. The method for preparing a Chinese date seed composite beverage for assisting in improving sleep according to claim 1, characterized in that The nutritional enhancer is gamma-aminobutyric acid and 0.008-0.03% salt.

9. The method for preparing a Chinese date seed composite beverage for assisting in improving sleep according to claim 1, characterized in that The acidulant-organic acid is citric acid, tartaric acid, malic acid and sodium citrate.

10. The method for preparing a Chinese date seed composite beverage for assisting in improving sleep according to claim 1, characterized in that: The antioxidant is vitamin C or sodium D-isoascorbate.

11. The method for preparing a Chinese date seed composite beverage for assisting in improving sleep according to claim 1, characterized in that The stabilizer is beta-cyclodextrin or sodium carboxymethyl cellulose.

12. A method for preparing a Chinese jujube seed composite beverage for assisting in improving sleep according to any one of claims 1 to 10, wherein the beverage is used for improving sleep.

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